Search Results
Results 451 - 500 of 2362
< 5 6 7 8 9 10 11 12 13 14 15 >
Maggioni Aldo P - - 2013
AIMS: To assess in a community setting how patients discharged alive after an acute coronary syndrome (ACS) are treated with statins. Specifically, the rate of prescription, the dosages, and 1-year adherence have been evaluated. METHODS AND RESULTS: From the ARNO Observatory, we carried out a record linkage analysis of discharge ...
Leitner Gabriel - - 2013
Real-time analysis of milk coagulation properties as performed by the AfiLab™ milk spectrometer introduces new opportunities for the dairy industry. The study evaluated the performance of the AfiLab™ in a milking parlor of a commercial farm to provide real-time analysis of milk-clotting parameters -Afi-CF for cheese manufacture and determine its ...
Maddux Franklin W - - 2013
Under the Patient Protection and Affordable Care Act of 2010, accountable care organizations (ACOs) will be the primary mechanism for achieving the dual goals of high-quality patient care at managed per capita costs. To achieve these goals in the newly emerging health care environment, the nephrology community must plan for ...
Fresa Raffaella - - 2013
Abstract Objectives: An optimized metabolic control during delivery is mandatory to prevent maternal-neonatal complications. The primary aim of this study was to evaluate the efficacy and safety of continuous subcutaneous insulin infusion (CSII) during delivery in pregnant women with type 1 diabetes. The secondary aim was to assess the impact ...
Rohner Deborah J - - 2013
ABSTRACT BACKGROUND: Uncertainty exists surrounding a "safe" dose limit to minimize radiation-induced cancer. Maximum occupational exposure is 20mSv/year averaged over five years with no more than 50mSv in any single year. Radiation exposure to the general population is less, but average dose in the United States has doubled in the ...
Kaur Matinder - - 2013
A new tellurophene-based π-conjugated polymer, PDTDPPTe, was synthesized. PDTDPPTe exhibits a smaller optical band gap (Eg(opt) = 1.25 eV) than thiophene-based PDTDPPT (Eg(opt) = 1.30 eV). Thin-film transistors comprising PDTDPPTe displayed outstanding performance (μmax = 1.78 cm(2) V(-1) s(-1), Ion/Ioff = 10(5-6)).
Randviir Edward P - - 2013
Screen printed carbon nanotube electrodes (SPEs) are explored as electroanalytical sensing platforms for the detection of capsaicin in both synthetic capsaicin solutions and capsaicin extracted from chillies and chilli sauces utilising both cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). It is found that the technique which is most applicable ...
Jung Dae Soo - - 2013
Nanostructured silicon electrodes have shown great potential as lithium ion battery (LIB) anodes because they can address capacity fading mechanisms originating from large volume changes of silicon alloys while delivering extraordinarily large gravimetric capacities. Nonetheless, synthesis of well-defined silicon nanostructures in an industrially adaptable scale still remains as a challenge. ...
Qin Zhihai - - 2013
Stromal restraints to cancer are critical determinants of disease but they remain incompletely understood. Here we report a novel mechanism for host surveillance against cancer contributed by S100A4+ (FSP1+) fibroblasts. Mechanistic studies of fibrosarcoma formation caused by subcutaneous injection of the carcinogen methylcholanthrene (MCA) had suggested that interferon-gamma receptor signaling ...
Inokuma Yasuhide - - 2013
X-ray single-crystal diffraction (SCD) analysis has the intrinsic limitation that the target molecules must be obtained as single crystals. Here we report a protocol for SCD analysis that does not require the crystallization of the sample. In our method, tiny crystals of porous complexes are soaked in a solution of ...
Gentle Madeleine E ME Division of Nephrology, Department of Medicine, Mount Sinai School of Medicine, One Gustave Levy Place, New York, NY 10029, - - 2013
TGFβ signaling plays a central role in the development of acute and chronic kidney diseases. Previous in vivo studies involved systemic alteration of TGFβ signaling, however, limiting conclusions about the direct role of TGFβ in tubular cell injury. Here, we generated a double transgenic mouse that inducibly expresses a ligand-independent ...
De Vita E E Lysholm Department of - - 2013
Inherited prion diseases represent over 15% of human prion cases and are a frequent cause of early onset dementia. The purpose of this study was to define the distribution of changes in cerebral volumetric and microstructural parenchymal tissues in a specific inherited human prion disease mutation combining VBM with VBA ...
Joo Min J - - 2013
Abstract Guidelines that recommend spirometry to confirm airflow obstruction among patients with suspected COPD are not routinely followed. We conducted a qualitative study to identify attitudes and barriers of primary care physicians to performing spirometry for patients with possible COPD. We conducted four focus groups, each with three primary care ...
Pagnamenta Alberto - - 2013
The time constant of the pulmonary circulation, or product of pulmonary vascular resistance (PVR) and compliance (Ca), called the RC-time, has been reported to remain constant over a wide range of pressures, etiologies of pulmonary hypertension, and treatments. We wondered whether increased wave reflection on proximal pulmonary vascular obstruction, like ...
Moorlock Greg - - 2013
Altruism has long been taken to be the guiding principle of ethical organ donation in the UK, and has been used as justification for rejecting or allowing certain types of donation. We argue that, despite this prominent role, altruism has been poorly defined in policy and position documents, and used ...
Pagni Marco - - 2013
MOTIVATION: Analysis of millions of pyro-sequences is currently playing a crucial role in the advance of environmental microbiology. Taxonomy independent, i.e. unsupervised clustering of these sequences is essential for the definition of Operational Taxonomic Units. For this application, reproducibility and robustness should be the most sought after qualities, but have ...
Al-Qahtani Saeed - - 2013
Objective: We present our experience in the minimal invasive management of post-operative complications associated with urinary diversions using ureteral access sheath (UAS) in antegrade approach. Patients and Methods: From 2005 to 2011, 21 antegrade flexible ureteroscopy (F-URS) were performed in 17 patients with a urinary diversion. Urinary diversions in this ...
Roberts James R - - 2013
Background. Control of environmental triggers (ETs) greatly improves asthma outcomes in children. Disseminating these findings to general pediatricians has not been well established. Methods. After delivering a structured and standardized presentation on ET identification and control to pediatricians, we surveyed them about knowledge and practices of ET assessment and management. ...
Coletta Adriana - - 2013
BACKGROUND: It is recommended that endurance athletes consume carbohydrate (CHO) supplements, providing 6-8% CHO concentration, during exercise > 60 minutes to improve athletic performance. Recently research has compared carbohydrate-protein (CHO-P) supplementation to the traditionally used CHO supplementation during endurance exercise, following these supplementation recommendations, in controlled settings, but not under ...
Clarke Luka A - - 2013
BACKGROUND: Microarray studies related to cystic fibrosis (CF) airway gene expression have gone some way in clarifying the complex molecular background of CF lung diseases, but have made little progress in defining a robust "molecular signature" associated with mutant CFTR expression. Disparate methodological and statistical analyses complicate comparisons between independent ...
Park Tai Hwan - - 2013
BACKGROUND AND PURPOSE: Several stroke risk scores for prediction of functional outcome have been developed, but rarely validated in Asian populations. We assessed the validity of the iScore, recently developed from Canadian stroke population, in an Asian stroke population from Korea. METHODS: We applied the iScore to 4061 eligible participants ...
Koçak Aslıhan Yonca - - 2013
Abstract Methotrexate (MTX) is an effective but potentially toxic treatment for psoriasis. We describe a patient who administered 20 mg daily of MTX for 5 d and presented with ulcerated and necrotic lesions on the psoriatic plaques, mouth erosions and hair loss. However, his psoriatic plaques and ulcerations totally healed rapidly within ...
Campos Catarina - - 2013
Myogenin (myog) encodes a highly conserved myogenic regulatory factor that is involved in terminal muscle differentiation. It has been shown in mammals that methylation of cytosines within the myog promoter plays a major role in regulating its transcription. In the present study, the Senegalese sole (Solea senegalensis) myog putative proximal ...
Cho Jae Hyung - - 2013
BACKGROUND: Ventricular septal rupture is a potentially fatal complication of acute myocardial infarction. Its incidence has declined with modern reperfusion therapy. In the era of percutaneous coronary interventions, it occurs a median of 18--24 hours after myocardial infarction and is most commonly associated with anterior myocardial infarction. We present a ...
Xu Chuan - - 2013
Cancer stem-like cells (CSLCs) are crucial in tumor initiation and progression, however, the underlying mechanism for the self-renewal of cancer cells remains undefined. In the study, immunohistochemical analysis of specimens freshly excised from patients with lung adenocarcinoma (LAC) showed that high expression of insulin-like growth factor 1 receptor (IGF-1R) in ...
Shrewsberry Adam Buddy - - 2013
Purpose: Correct length of ureteral stent is important in minimizing post-placement discomfort and stent migration. We describe and validate a method to accurately measure ureteral length. Materials and Methods: Ureteral length in 48 patients undergoing ureteral stent placement for urolithiasis was measured by CT (total thickness of axial slices between ...
Li Lin - - 2013
Abstract 1. In the present study, we investigated the impact of 1.0% ropivacaine on the ultrastructure and proteome of the rat spinal cord. 2. Rats received three injections (90-min intervals, 0.2 mL/kg) of 0.9% NaCl, 0.5% ropivacaine or 1.0% ropivacaine via an implanted intrathecal catheter. Transmission electron microscopy was performed to ...
Simmer Karen - - 2013
Parenteral nutrition (PN) has become an integral part of clinical management of very low birth weight premature neonates. Traditionally different components of PN are prescribed individually considering requirements of an individual neonate (IPN). More recently, standardised PN formulations (SPN) for preterm neonates have been assessed and may have advantages including ...
Vervliet Bram - - 2013
Exposure-based treatments for clinical anxiety generally are very effective, but relapse is not uncommon. Likewise, laboratory studies have shown that conditioned fears are easy to extinguish, but they recover easily. This analogy is striking, and numerous fear extinction studies have been published that highlight the processes responsible for the extinction ...
Myers Anna Cardiakidis - - 2013
Abstract Aim: To study the effects of intravitreally injected triamcinolone acetonide (TA) and/or its preservative benzyl alcohol (BA) in healthy rabbit retina. Methods: Forty-eight rabbits (aged 4 months, body weight ≈3 kg) were randomized into four groups (n = 12). They were examined with electroretinography (ERG) prior to drug exposure, and then injected ...
Wik Elisabeth - - 2013
PURPOSE: High Stathmin expression is recently associated with clinical progress of endometrial cancers. Stathmin protein activity is modulated by phosphorylation, and the Serine38 site is one of four Stathmin phospho-sites. The presence and significance of pStathmin(S38) is largely unknown in human cancers, and we here examined the associations between this ...
Lin Ruei-Lung RL Department of Physiology, University of Kentucky, Lexington, Kentucky 40536-0298, - - 2013
Inhalation of tumor necrosis factor-alpha (TNF-α), a proinflammatory cytokine, induces airway hyperresponsiveness, and the underlying mechanism is not fully understood. Hypersensitivity of vagal bronchopulmonary C-fiber afferents is known to contribute to the airway hyperresponsiveness during an airway inflammatory reaction. Because activation of these afferents can elicit pulmonary chemoreflexes, this study ...
K Sik-Szeloch Agata - - 2013
BACKGROUND: Members of the genus Klebsiella are among the leading microbial pathogens associated with nosocomial infection. The increased incidence of antimicrobial resistance in these species has propelled the need for alternate/combination therapeutic regimens to aid clinical treatment. Bacteriophage therapy forms one of these alternate strategies. METHODS: Electron microscopy, burst size, ...
Wilmot Roussel Hortense - - 2013
Context:The cortisol secretion of adrenocortical adenomas can be either subtle or overt. The mechanisms leading to the autonomous hypersecretion of cortisol are unknown.Objective:To identify the gene expression profile associated with the autonomous and excessive cortisol secretion of adrenocortical adenomas.Patients and Methods:The transcriptome of 22 unilateral adrenocortical adenomas (5 non-secreting, 6 ...
Marrodán Md - - 2013
OBJECTIVE: To analyse the association between waist-to-height ratio (WtHR) and body fat and to develop predictive adiposity equations that will simplify the diagnosis of obesity in the paediatric age group. DESIGN: Cross-sectional study conducted in Spain during 2007 and 2008. Anthropometric dimensions were taken according to the International Biology Program. ...
Karimi Amine - - 2013
BACKGROUND: Restenosis after percutaneous transluminal angioplasty (PTA) of the superficial femoral artery (SFA) may occur in 45% of patients at 2 years follow-up. Paclitaxel-coated balloons have been found to reduce neointimal hyperplasia, and thus reduce restenosis. Recently, the Legflow(R) paclitaxel-coated balloon (Cardionovum Sp.z.o.o., Warsaw, Poland) (LPEB) has been introduced. This ...
Campos-Parra Alma D - - 2013
OBJETIVE:: In patients with non-small cell lung cancer (NSCLC), knowledge of the epidermal growth factor receptor (EGFR) mutation status is fundamental for selecting the treatment involving EGFR-tyrosine kinase inhibitors (EGFR-TKIs). Little information is available regarding the response and progression-free survival (PFS) in platinum-based chemotherapy (CT) versus EGFR-TKIs in the presence ...
Hunter C J - - 2013
Members of the genus Cronobacter are an emerging group of opportunist Gram-negative pathogens. This genus was previously thought to be a single species, called Enterobacter sakazakii. Cronobacter spp. typically affect low-birth-weight neonates, causing life-threatening meningitis, sepsis and necrotizing enterocolitis. Outbreaks of disease have been associated with contaminated infant formula, although ...
Fraser Hunter B HB Department of Biology, Stanford University, Stanford, California 94305, USA. - - 2013
The molecular basis of adaptation--and, in particular, the relative roles of protein-coding versus gene expression changes--has long been the subject of speculation and debate. Recently, the genotyping of diverse human populations has led to the identification of many putative "local adaptations" that differ between populations. Here I show that these ...
Horsburgh C Robert - - 2013
BACKGROUND: Antibiotic resistance is a major barrier to the continued success of antibiotic treatment. Such resistance is often generated by overly long durations of antibiotic treatment. A barrier to identifying the shortest effective treatment duration is the cost of the sequence of clinical trials needed to determine shortest optimal treatment ...
He Huiling H Human Cancer Genetics Program and Department of Molecular Virology, Immunology, and Medical Genetics, Ohio State University Comprehensive Cancer Center, the Ohio State University, Columbus, Ohio 43210, - - 2013
Papillary thyroid carcinoma (PTC) shows high heritability, yet efforts to find predisposing genes have been largely negative. The objective of this study was to identify susceptibility genes for PTC. A genome-wide linkage analysis was performed in 38 families. Targeted association study and screening were performed in 2 large cohorts of ...
Lavi Ayal - - 2013
Alterations in the levels of synaptic proteins affect synaptic transmission and synaptic plasticity. However, the precise effects on neuronal network activity are still enigmatic. Here, we utilized microelectrode array (MEA) to elucidate how manipulation of the presynaptic release process affects the activity of neuronal networks. By combining pharmacological tools and ...
Suguna Narasimhulu Sukumar - - 2013
Objective. Our hypothesis is that specific proinflammatory and anti-inflammatory urinary cytokines are useful in the diagnostic evaluation of risk for sepsis in term neonates. We conducted a pilot, prospective hospital-based longitudinal observational study to test the urine of term neonates with a 13 biomarker panel of cytokines. Methods. Infants were ...
Bruschi Giuseppe G A De Gasperis Cardiology & Cardiac Surgery Department, Niguarda Ca' Granda Hospital, Milan, Italy. - - 2013
Transcatheter aortic valve implantation has emerged as a valuable option to treat patients with symptomatic severe aortic stenosis, who are not being considered for surgery because of significant comorbidities. Concerns exist over treating patients who have previously undergone mitral valve surgery for possible interference between the percutaneous aortic valve and ...
Li Hao - - 2013
ABSTRACT BACKGROUND: Endothelial progenitor cells (EPCs) are involved in endothelium repair of acute lung injury (ALI). Numerous studies have demonstrated that statins can promote EPCs function in vitro and in vivo; therefore, the purpose of this study was to determine whether simvastatin enhances the function of EPCs participating in the ...
Martín Ignacio - - 2013
βIII-Gal, a member of the chickpea β-galactosidase family, is the enzyme responsible for the cell wall autolytic process. This enzyme, whose activity increases during epicotyl growth, displays significant hydrolytic activity against cell wall pectins and its natural substrate has been determined as an arabinogalactan from the pectic fraction of the ...
Wilson C G CG Center for Craniofacial Regeneration, University of Michigan School of Dentistry, Ann Arbor, MI, - - 2013
Spatial and temporal patterns of bone morphogenetic protein (BMP) signaling are crucial to the assembly of appropriately positioned and shaped bones of the face and head. This review advances the hypothesis that reconstitution of such patterns with cutting-edge gene therapies will transform the clinical management of craniofacial bone defects attributed ...
Tawfick Sameh - - 2013
Elastocapillary self-assembly is emerging as a versatile technique to manufacture three-dimensional (3D) microstructures and complex surface textures from arrangements of micro- and nanoscale filaments. Understanding the mechanics of capillary self-assembly is essential to engineering of properties such as shape-directed actuation, anisotropic wetting and adhesion, and mechanical energy transfer and dissipation. ...
Grace Sherry L - - 2013
BACKGROUND: Patient and provider-related factors affecting access to cardiac rehabilitation (CR) have been extensively studied, but health-system administration factors have not. The objectives of this study were to investigate hospital administrators' (HA) awareness and knowledge of cardiac rehabilitation (CR), perceptions regarding resources for and benefit of CR, and attitudes toward ...
Harpur Brock A - - 2013
The genomes of eusocial insects have a reduced complement of immune genes - an unusual finding considering that sociality provides ideal conditions for disease transmission. Three hypotheses have been invoked to explain this finding: 1) social insects are attacked by fewer pathogens, 2) social insects have effective behavioral or 3) ...
< 5 6 7 8 9 10 11 12 13 14 15 >