Search Results
Results 1 - 50 of 2429
1 2 3 4 5 6 7 8 9 10 >
Uebel Kerry E KE Department of Internal Medicine, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa. - - 2013
Integration of HIV care into primary care is a potential strategy to improve access to antiretroviral therapy (ART) in high-burden countries. This study was conducted to determine the effect of integration of HIV care on the survival of patients needing ART. A questionnaire was used to measure the integration of ...
Gordon Michael S MS Friends Research Institute, Inc., 1040 Park Avenue, Suite 103, Baltimore, MD 21201, USA. - - 2013
Many probationers and parolees do not receive HIV testing despite being at increased risk for obtaining and transmitting HIV. A two-group randomized controlled trial was conducted between April, 2011 and May, 2012 at probation/parole offices in Baltimore, Maryland and Providence/Pawtucket, Rhode Island. Male and female probationers/parolees were interviewed (n = ...
Soysa Radika R Department of Biochemistry and Molecular Biology, Oregon Health and Science University, Portland, Oregon 97239, - - 2013
The TcPOT1.1 gene from Trypanosoma cruzi encodes a high affinity putrescine-cadaverine transporter belonging to the APC (amino acid/polyamine/organocation) transporter superfamily. No experimental three-dimensional structure exists for any eukaryotic member of the APC family, and thus the structural determinants critical for function of these permeases are unknown. To elucidate the key ...
Chen Yin-Ting - - 2013
Stress fractures are a common type of overuse injury in athletes. Females have unique risk factors such as the female athlete triad that contribute to stress fracture injuries. We review the current literature on risk factors for stress fractures, including the role of sports participation and nutrition factors. Discussion of ...
Kimmel April D AD Department of Healthcare Policy and Research, Virginia Commonwealth University School of Medicine, Richmond, VA 23298-0430, USA. - - 2013
Guidelines recommend antiretroviral therapy (ART) initiation at CD4 <350 cells per microliter for HIV-infected individuals in resource-limited settings. However, funding for treatment expansion remains uncertain. We forecast the mortality impact of ART expansion alternatives in Haiti. We used data from Haiti to develop a country-specific model of HIV disease. The ...
Strbian Daniel D Department of Neurology, University of Helsinki, Helsinki, Finland. - - 2013
To evaluate the impact of extensive baseline ischemic changes on functional outcome after thrombolysis of basilar artery occlusion (BAO), and to study the effect of time to treatment in the absence of such findings. We prospectively evaluated 184 consecutive patients with angiography-proven BAO. The majority of patients received intravenous alteplase ...
Glei Dana A DA Center for Population and Health, Georgetown University, Washington, DC, USA. - - 2013
Allostatic load theory implies a relationship between exposure to psychological stress and multi-system physiological dysregulation. We used data from population-based samples of men and women in Russia (Moscow; n = 1800; age, mean 68.6 years), Taiwan (n = 1036; 65.6 years) and the United States (US; n = 1054; 58.0 years) -- which are likely to ...
Beck Jennifer J - - 2013
This article reports on two children with congenital unilateral tibial dysplasia with lateral bowing with no associated sagittal plane deformity. In both cases, it is associated with ipsilateral duplication of the hallux. Long-term follow-up of the patients showed spontaneous, almost complete resolution of the bowing without progressing into fracture or ...
Maniyar Farooq H - - 2013
Chronic migraine is a relatively common disorder in neurological terms that causes very significant disability at a high cost. The precise mechanisms behind the progression of episodic migraine to chronic migraine are not well understood. Functional neuro-imaging works on the basis that neuronal activations are associated with changes in regional ...
Klein Thomas - - 2013
Implantable cardioverter-defibrillators (ICDs) significantly reduce mortality in patients with depressed left ventricular ejection fraction (LVEF) and heart failure (HF). However, shortcomings of LVEF to accurately identify those at greatest risk of ventricular tachyarrhythmias have led to the pursuit of alternative means to refine qualification criteria for ICD implantation. It is ...
Doyle Timothy J TJ School of Molecular Biosciences, Washington State University, Pullman, WA 99164, - - 2013
Recent evidence has linked human phthalate exposure to abnormal reproductive and hormonal effects. Phthalates are plasticizers that confer flexibility and transparency to plastics, but they readily contaminate the body and the environment. In this study, timed pregnant CD1 outbred mice were treated with di-(2-ethylhexyl) phthalate (DEHP) from Embryonic Day 7 ...
McKenzie Erica R ER Department of Civil and Environmental Engineering, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA. - - 2013
A novel fractionation method, based on both particle size and settling characteristics, was employed to examine metal distributions among five fractions. In-stream and stormwater runoff samples were collected from four land use types: highway, urban, agricultural (storm event and irrigation), and natural. Highway samples contained the highest dissolved concentrations for ...
Cinciripini Paul M PM Department of Behavioral Science, The University of Texas MD Anderson Cancer Center, Houston, TX 77230-1439, USA. - - 2013
Given the actions of varenicline tartrate and bupropion hydrochloride sustained-release (SR) on neurobiological targets related to affect and reward, it is thought that the modulation of nicotine withdrawal symptoms may contribute to their effectiveness. To assess the relative efficacy of varenicline and bupropion SR plus intensive counseling on smoking cessation ...
Boivin Michael J MJ Department of Psychiatry and Neurology/Ophthalmology, Michigan State University, East Lansing, MI 48824 48824, USA. - - 2013
Mediational intervention for sensitizing caregivers (MISC) is a structured program enabling caregivers to enhance their child's cognitive and emotional development through daily interactions. The principal aim was to evaluate if a year-long MISC caregiver training program produced greater improvement in child cognitive and emotional development compared with a control program. ...
Belsky Daniel W DW Department of Health Policy and Management, Gillings School of Public Health, University of North Carolina–Chapel Hill, NC, - - 2013
Genome-wide hypothesis-free discovery methods have identified loci that are associated with heavy smoking in adulthood. Research is needed to understand developmental processes that link newly discovered genetic risks with adult heavy smoking. To test how genetic risks discovered in genome-wide association studies of adult smoking influence the developmental progression of ...
Farzan Shohreh F SF Department of Community and Family Medicine and The Norris Cotton Cancer Center, Section of Biostatistics and Epidemiology, Geisel School of Medicine at Dartmouth, One Medical Center Drive, Lebanon, NH 03756, - - 2013
Human papillomavirus (HPV) infection is common worldwide and, in immunodeficient populations, may contribute to the pathogenesis of keratinocyte cancers, particularly squamous cell carcinomas (SCC). However, their role in SCC in the general population is less clear. We conducted a comprehensive analysis to investigate the independent effects of seropositivity for cutaneous ...
Lie M L S ML Institute of Health and Society, Newcastle University, Newcastle upon Tyne, - - 2013
To explore factors influencing post-natal health behaviours following the experience of gestational diabetes, and to elicit women's views about the feasibility of lifestyle intervention to prevent diabetes during the first 2 years after childbirth. Qualitative study using semi-structured interviews with women who had gestational diabetes. In phase 1 (31 women), ...
Ceballos-Osuna Lina - - 2013
Intertidal zone organisms naturally experience daily fluctuations in pH, presently reaching values beyond what is predicted for open ocean surface waters from ocean acidification (OA) by the year 2100, and thus present an opportunity to study the pH sensitivity of organisms that are presumably adapted to an acidified environment. The ...
Carter Hayley A - - 2013
Absorption of elevated atmospheric CO2 is causing surface ocean pH to decline, a process known as ocean acidification (OA). To date, few studies have assessed the physiological impacts of OA on early life-history stages of intertidal organisms, which transition from habitats with fluctuating pH (intertidal zone) to relatively stable (pelagic ...
Wright Christian D - - 2013
Many xeric organisms maintain water balance by relying on dietary and metabolic water rather than free water, even when free water may be available. For such organisms, hydric state may influence foraging decisions, since meal consumption is meeting both energy and water demands. To understand foraging decisions it is vital ...
Flack Andrea - - 2013
In many species, group members obtain benefits from moving collectively, such as enhanced foraging efficiency or increased predator detection. In situations where the group's decision involves integrating individual preferences, group cohesion can lead to more accurate outcomes than solitary decisions. In homing pigeons, a classic model in avian orientation studies, ...
Love-Chezem Tiffany - - 2013
Antipredator defenses are ubiquitous and diverse. Ink secretion of sea hares (Aplysia) is an antipredator defense acting through the chemical senses of predators by different mechanisms. The most common mechanism is ink acting as an unpalatable repellent. Less common is ink secretion acting as a decoy (phagomimic) that misdirects predators' ...
Sundberg Eric J - - 2013
Asthma is a debilitating chronic inflammatory disease of the airways that results in shortness of breath, wheezing and coughing, often triggered by inhalation of common allergens. The prevalence and severity of asthma has increased dramatically over the last several decades to the point where several hundred million people worldwide are ...
Sauter Margret - - 2013
Both Met (methionine) and SAM (S-adenosylmethionine), the activated form of Met, participate in a number of essential metabolic pathways in plants. The subcellular compartmentalization of Met fluxes will be discussed in the present review with respect to regulation and communication with the sulfur assimilation pathway, the network of the aspartate-derived ...
Hindley Christopher - - 2013
PSCs (pluripotent stem cells) possess two key properties that have made them the focus of global research efforts in regenerative medicine: they have unlimited expansion potential under conditions which favour their preservation as PSCs and they have the ability to generate all somatic cell types upon differentiation (pluripotency). Conditions have ...
Ekemen Zeynep Z Department of Mechanical Engineering, University College London, Torrington Place, London WC1E 7JE, United - - 2013
Conventional fabrication techniques and structures employed in the design of silk fibroin (SF) based porous materials provide only limited control over pore size and require several processing stages. In this study, it is shown that, by utilizing electrohydrodynamic bubbling, not only can new hollow spherical structures of SF be formed ...
Anzini Maurizio - - 2013
A series of 3-substituted 1,5-diarylpyrroles bearing a nitrooxyalkyl side chain linked to different spacers were designed. New classes of pyrrole-derived nitrooxyalkyl inverse esters, carbonates, and ethers (7-10) as COX-2 selective inhibitors and NO donors were synthesized and are herein reported. By taking into account the metabolic conversion of nitrooxyalkyl ethers ...
Sharma Anurodh - - 2013
The caprine Insulin like Growth Factor1 (IGF1) gene was analyzed for identification of single nucleotide polymorphisms (SNPs) and genetic structuring of Indian goat breeds. A panel of 80 samples belonging to nine Indian goat breeds (Capra hircus) including three large sized breeds (Jamunapari, Beetal and Jakhrana); three medium sized breeds ...
Untiet Sarah - - 2013
At the beginning of the 20th Century, cervical cancer was the leading cause of death from cancer in women. A marked decline in cervical cancer has been observed since the 1960s, in parallel with the introduction of the Papanicolau (Pap) test as a cytological screening method. Today, Pap smear screening ...
Wong K F - - 2013
Dicentric assay is the international gold standard for cytogenetic biodosimetry after radiation exposure, despite being very labour-intensive, time-consuming, and highly expertise-dependent. It involves the identification of centromeres and structure of solid-stained chromosomes and the enumeration of dicentric chromosomes in a large number of first-division metaphases of cultured T lymphocytes. The ...
Voicu Victor - - 2013
Background: Extreme efforts are made for the structural diversification of oximes used as AChE reactivators. Co-administration of different oximes should also be considered as a solution in therapy. Consequently, development of selective assays of oximes in biological matrices is of major importance. Results: Three chromatographic separation mechanisms were evaluated: hydrophilic-interaction ...
Roca André - - 2013
The ability to anticipate and to make decisions is crucial to skilled performance in many sports. We examined the role of and interaction between the different perceptual-cognitive skills underlying anticipation and decision making. Skilled and less skilled players interacted as defenders with life-size film sequences of 11 versus 11 soccer ...
Pfeifer Gail M - - 2013
New state senate and house bills could eliminate that requirement.
Gómez Enrique - - 2013
Although allergic drug reactions have been considered to be immediate (IgE mediated) or delayed (T-cell effector mechanisms), accelerated reactions have also been defined; however, they have not been sufficiently studied. To study the mechanisms involved in accelerated reactions to amoxicillin. We monitored the response in 3 patients who had an ...
Wang Yan - - 2013
To investigate the in vitro effect of caffeic acid phenethyl ester (CAPE), a NF-κB inhibitor, on the apoptosis of osteoarthritic (OA) chondrocytes and on the regulation of the gelatinases matrix metalloproteinase 2 (MMP-2) and matrix metalloproteinase 9 (MMP-9). Annexin V-FITC/propidium iodide (PI) labeling and western blotting were used to observe ...
Martins Liline Maria Soares - - 2013
Aim: To identify immunoreactive proteins of Cryptococcus gattii genotype VGII and their B-cell epitopes. Materials & methods: We combined 2D gel electrophoresis, immunoblotting and mass spectrometry to identify immunoreactive proteins from four strains of C. gattii genotype VGII (CG01, CG02, CG03 and R265). Next, we screened the identified proteins to ...
Hazelton Briony - - 2013
Hendra virus, a member of the family Paramyxoviridae, was first recognized following a devastating outbreak in Queensland, Australia, in 1994. The naturally acquired symptomatic infection, characterized by a rapidly progressive illness involving the respiratory system and/or CNS, has so far only been recognized in horses and humans. However, there is ...
Probst-Hensch Nicole M - - 2013
The promises resulting from the decoding of the human genome have not been fulfilled to the extent as expected. At the same time it is fair to say that the results of recent genetic research have not been useless. In the area of ​​​​familial cancer the clinical benefit of genetic ...
Zhou Guang Bin - - 2013
Bovine oocytes are less likely to undergo successful cryopreservation than cleavage-stage embryos. Bovine oocytes characteristically contain high levels of lipids that represent one of the major obstacles limiting efficient cryopreservation. These droplets together with structures such as cumulus cells, zona pellucida, cytoplasm membrane, cortical granules, mitochondria, spindle, and cytoskeleton (microtubles ...
Egger Matthias - - 2013
Screening for malignant disease aims to reduce the population risk of impaired health due to the tumor in question. Screening does not only entail testing but covers all steps required to achieve the intended reduction in risk, from the appropriate information of the population to a suitable therapy. Screening tests ...
Pulcini Joyce - - 2013
Milestones and challenges in implementing the ACA.
Jellins Jessica - - 2013
As a clinical entity the Brugada syndrome has existed since 1992 and has been associated with a high risk of sudden cardiac death predominately in younger males. Patients can present with symptoms (ie syncope, palpitations, aborted sudden cardiac death) and asymptomatically. Its three characteristic electrocardiographic patterns can occur both spontaneously ...
Kan Raymond Wm - - 2013
OBJECTIVES. (1) To evaluate the safety and efficacy of supine percutaneous nephrostomy, nephrolithotomy, and combined percutaneous nephrolithotomy and ureteroscopic lithotripsy. (2) To describe the skill-acquiring process in supine procedures and share our initial experience. DESIGN. Three-staged case series with prospective data collection. SETTING. Two public hospitals in Hong Kong. PATIENTS ...
Meier-Augenstein Wolfram - - 2013
Measurement of the relative abundance of (2)H (expressed in δ (2)H values) in tissues of plants, wildlife and people has evolved into a powerful forensic tool. The approach is based on the strong linkage between spatial patterns of δ (2)H values in precipitation at local and continental scales, and the ...
Wong Edward Hc - - 2013
OBJECTIVES. To assess the outcome of acute ischaemic stroke patients who received intra-arterial therapy in our unit. DESIGN. Case series. SETTING. A tertiary hospital in Hong Kong. PATIENTS. Patients with ischaemic stroke due to large artery occlusion treated within 6 hours from symptom onset between January 2007 and May 2011. ...
Kottner Jan - - 2013
Comparative quality measurements and evaluations in nursing play significant roles. Quality measures are affected by systematic and random error. Statistical Process Control (SPC) offers a method to take random variation adequately into account. In this article, control charts are introduced. Those are graphical displays to show quality measures over time. ...
Luo Heng - - 2013
To study the effect of fleroxacin (FLRX) on biological properties of Bloom (BLM) helicase catalytic core (BLM642-1290 helicase) in vitro and the molecular mechanism of interaction between the two molecules. DNA-binding and unwinding activities of BLM642-1290 helicase were assayed by fluorescence polarization and gel retardation assay under conditions that the ...
Egan Timothy J - - 2013
Malaria remains a major international health challenge. Resistance to a number of existing drugs and evidence of the emergence of artemisinin resistance has emphasized the need for new antimalarials. A new approach has been the preparation of dual-function compounds that include a chloroquine-like antimalarial group and a group that resembles ...
Wallis Laura - - 2013
Face-to-face handoffs are still valuable; bedside handoffs, less so.
Ng Beverly Ck - - 2013
OBJECTIVE. To review clinical characteristics, imaging modalities, and treatment outcomes of patients referred to a multidisciplinary clinic for management of vascular malformations. DESIGN. Retrospective case series. SETTING. Multidisciplinary vascular malformation out-patient referral clinic in a teaching hospital in Hong Kong. PATIENTS. The 141 attendees of the clinic from August 2005 ...
1 2 3 4 5 6 7 8 9 10 >