Search Results
Results 351 - 400 of 3226
< 3 4 5 6 7 8 9 10 11 12 13 >
Chen Feng F Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, - - 2013
Blood-brain barrier (BBB) dysfunction in acute liver failure (ALF) results in increased BBB permeability that often precludes the patients from obtaining a life-saving liver transplantation. It remains controversial whether matrix metalloproteinase-9 (MMP-9) from the injured liver contributes to the deregulation of BBB function in ALF. We selectively upregulated a physiologic ...
Anouti Mérièm - - 2013
This study describes the use of the pyrrolidinium nitrate ([Pyrr][NO3]) protic ionic liquid (PIL) in a mixture with gamma butyrolactone (γ-BL) as an electrolyte for carbon-based supercapacitors with an operating voltage of 2.0 V and at very low temperature. Thermal and transport properties of this electrolyte were firstly evaluated from ...
Patnaik M M - - 2013
We evaluated the prognostic relevance of several clinical and laboratory parameters in 226 Mayo Clinic patients with chronic myelomonocytic leukemia (CMML): 152 (67%) males and median age 71 years. At a median follow-up of 15 months, 166 (73%) deaths and 33 (14.5%) leukemic transformations were documented. In univariate analysis, significant ...
Cho Jung Sang - - 2013
The effect of chloride-substitution on bioactivity and osteoconductivity of hydroxyapatite (OHAp) was newly investigated. Chloride-substituted hydroxyapatites (ClAp) with low and high chloride concentrations were synthesized by reacting Ca(OH)2 and H3 PO4 with NH4 Cl of low and high concentrations, with subsequent sintering. As a control, pure OHAp was prepared under ...
Reith Maarten E A ME Department of Psychiatry, and Biochemistry and Molecular Pharmacology, Alexandria Center for Life Sciences, New York University School of Medicine, 450 E 29th Street, New York, NY 10016, USA. - - 2013
The study reported by Wenge and Bönisch in this issue provides critical structural information regarding extracellular loop 2 (EL2) of the human norepinephrine transporter (NET). A systematic search among all 10 cysteine and 13 histidine residues in NET led to His222 in EL2 as the target for N-ethylmaleimide: its alkylation ...
Compson Zacchaeus G - - 2013
Reciprocal subsidies between rivers and terrestrial habitats are common where terrestrial leaf litter provides energy to aquatic invertebrates while emerging aquatic insects provide energy to terrestrial predators (e.g., birds, lizards, spiders). We examined how aquatic insect emergence changed seasonally with litter from two foundation riparian trees, whose litter often dominates ...
Li Shan - - 2013
To investigate the role of miR-215 in the relapse following radical surgery of colorectal cancer patients. The clinical data and surgical frozen tumor tissues were retrospectively collected from 125 stage II/III colorectal cancer patients, which contained 60 patients who relapsed and 65 patients who did not relapse within 3 years after ...
Deneo-Pellegrini Hugo - - 2013
OBJECTIVE: The aim of this study was to investigate the association between nutrient-based dietary patterns and squamous cell cancers of the head and neck. METHODS: We used a case-control study which included 548 cases and 548 controls. From these participants, we derived 23 nutrients and they were then submitted to ...
Salgado-Maldonado Guillermo - - 2013
A redescription of Neoechinorhynchus (Neoechinorhynchus) golvani Salgado-Maldonado (An Inst Biol Univ Nal Autón Méx, Ser Zool 49:35-47, 1978) is presented, based on adult specimens collected from the type host Paraneetroplus fenestratus from the type location, the Lago de Catemaco lake, Veracruz state, Mexico, and its presence is recorded in other ...
Yang Miao - - 2013
A new chiral copper borophosphate, LiCu2[BP2O8(OH)2] (), was crystallized from achiral inorganic raw materials in boric acid flux reaction. The structure features a 9-ring channel enclosed by triple right-handed helices. The bulk sample exhibits optical activity confirmed by circular dichroism (CD) spectra, indicating an interesting spontaneous resolution phenomenon.
Huppelschoten Aleida G - - 2013
OBJECTIVE: To study the effect of subcutaneous tissue closing and the effect of two different skin closure methods at cesarean section on long-term cosmetic results. DESIGN: Randomized controlled trial. SETTING: A large teaching hospital in the Netherlands. POPULATION: Women undergoing a cesarean section. METHODS: Women undergoing a cesarean section were ...
Abdolahpur Monikh Fazel - - 2013
The concentration of heavy metals was determined in tissues of sole (Euryglossa orientalis), mullet (Liza abu) and croacker fish (Johnius belangerii) from Musa estuary. Generally, the highest concentration of the studied metals in the three species was found in the liver tissue. The levels of Cd and Cu in fish ...
Sohal Davendra P S - - 2013
PURPOSE: Platinum compounds or bevacizumab, in combination with gemcitabine, achieved good response rates in early studies in advanced pancreatic cancer. This prompted an evaluation of an aggressive approach to allow better local control and resectability in locally advanced disease. METHODS: We piloted a combination of gemcitabine/oxaliplatin/bevacizumab Q2w for four cycles, ...
Baeva Larissa F - - 2013
This study examined the effect of HA molecular weight on immune response. HA with molecular weights ranging from the unitary disaccharide unit (400 Dalton) up to 1.7x10(6) Dalton and with very low endotoxin contamination level (less than 0.03 EU/mg) was used. Primary human monocyte/macrophage cultures were assayed for IL-1β production ...
Bowne-Anderson Hugo - - 2013
A key question in understanding microtubule dynamics is how GTP hydrolysis leads to catastrophe, the switch from slow growth to rapid shrinkage. We first provide a review of the experimental and modeling literature, and then present a new model of microtubule dynamics. We demonstrate that vectorial, random, and coupled hydrolysis ...
Reulbach Udo - - 2013
AIM: To explore the association between weight and bullying; considering victims and perpetrators as two aspects of bullying, and subjective perception and objective measurement as two aspects of weight. METHODS: This study is based on the first wave of data collection from Growing Up in Ireland - the National Longitudinal ...
Arjona-Sanchez Alvaro - - 2013
BACKGROUND: Pseudomyxoma peritonei (PMP) is a rare disease with an incidence rate of approximately 1 per million a year. During the past few years, there has been a survival benefit for these patients treated by complete cytoreduction and perioperative chemotherapy. Better survival rates were found in the adenomucinosis group than ...
Pereira Morais Marta P - - 2013
Glycated proteins are important biomarkers for age-related disorders, however their analysis is challenging because of the complexity of the protein-carbohydrate adducts. Here we report a method that enables the detection and identification of individual glycated proteins in complex samples using fluorescent boronic acids in gel electrophoresis. Using this method we ...
Rahu Kaja K Department of Epidemiology and Biostatistics, National Institute for Health Development, Tallinn, Estonia. - - 2013
This study examined cancer incidence (1986-2008) and mortality (1986-2011) among the Estonian Chernobyl cleanup workers in comparison with the Estonian male population. The cohort of 4810 men was followed through nationwide population, mortality and cancer registries. Cancer and death risks were measured by standardised incidence ratio (SIR) and standardised mortality ...
Komori Takashi - - 2013
Dysembryoplastic neuroepithelial tumor (DNT) is a benign glioneuronal tumor, occurring in children and adolescents, typically associated with drug-resistant partial seizures. Pathologically, DNT is characterized by a specific glioneuronal element that is comprised of oligodendroglia-like cells (OLC) and floating neurons. The definition of DNT is currently controversial and the incidence of ...
Vlahou Antonia - - 2013
Clinical Proteomics has traveled long way pinpointing potential biomarkers for a variety of diseases. However, the absence of clinical implementation of proteomics findings has led to a frank evaluation and re-consideration of applied practices in biomarker discovery, recruitment of technological tools for biomarker verification and generation of new guidelines for ...
Maxey Dawn M - - 2013
Because most medications for pediatric pulmonary hypertension (PH) are used off label and based on adult trials, little information is available on pediatric-specific adverse events (AEs). Although drug manufacturers are required to submit postmarket AE reports to the Food and Drug Administration (FDA), this information is rarely transmitted to practitioners. ...
Bogacki Paul - - 2013
BACKGROUND: Medicago truncatula Gaertn. (barrel medic) is cultivated as a pasture legume for its high protein content and ability to improve soils through nitrogen fixation. Toxic concentrations of the micronutrient Boron (B) in agricultural soils hamper the production of cereal and leguminous crops. In cereals, the genetic analysis of B ...
Borzomati Domenico - - 2013
Bevacizumab is largely used in colorectal cancer patients. Postsurgical healing complications have been described for patients following treatment with Bevacizumab. We report three cases of spontaneous intestinal perforation following infusion of Bevacizumab. From January 2002 through October 2010, Bevacizumab was delivered in 143 patients. Spontaneous intestinal perforation occurred in 3 ...
Yamada Yasuhide - - 2013
BACKGROUND: Sorafenib inhibits several receptor tyrosine kinases involved in tumor progression and angiogenesis. S-1, an oral fluorouracil antitumor drug, plus cisplatin (CDDP) is the standard regimen for advanced gastric adenocarcinoma (AGC) in Japan. The purpose of this phase I study was to evaluate the safety, pharmacokinetics, and preliminary efficacy of ...
Dao Mo - - 2013
BACKGROUND: Angiogenesis is a critical part of the endogenous repair process in brain injury and disease, and requires at least two sequential steps. First, angiogenic sprouting of endothelial cells occurs, which entails the initial proliferation of endothelial cells and remodeling of the surrounding extracellular matrix. Second, vessel stabilization is necessary ...
Wu Junbiao - - 2013
A new open-framework zinc phosphate with 12-ring channels has been solvothermally synthesized by using the in situ generated methylviologen as the template, which exhibits multi-photoactive properties such as photochromism, photoelectricity and fluorescence.
Islam Nilufar - - 2013
The optimization of chlorine dosage and the number of booster locations is an important aspect of water quality management in distribution networks. Booster chlorination helps to maintain uniformity and adequacy of free residual chlorine concentration, essential for safeguarding against microbiological contamination. Higher chlorine dosages increase free residual chlorine concentration but ...
Mishra Shashank - - 2013
During the past few years, the production of natural value-added compounds from microbial sources has gained tremendous importance. Due to an increase in consumer demand for natural products, various food and pharmaceutical industries are continuously in search of novel metabolites obtained from microbial biotransformation. The exploitation of microbial biosynthetic pathways ...
Tocheva Elitza I EI Division of Biology, California Institute of Technology, 1200 E California Blvd, Pasadena, CA 91125, - - 2013
While vegetative Bacillus subtilis cells and mature spores are both surrounded by a thick layer of peptidoglycan (PG, a polymer of glycan strands cross-linked by peptide bridges), it has remained unclear whether PG surrounds prespores during engulfment. To clarify this issue, we generated a slender ΔponA mutant that enabled high-resolution ...
Yoo Hye Jin - - 2013
Omentin-1 is an adipokine implicated in diabetes, inflammation, and cardiovascular disease. However, no prospective studies have examined the impact of circulating omentin-1 levels on arterial stiffening in patients with type 2 diabetes mellitus. For the purpose of this study, we recruited 120 patients with type 2 diabetes mellitus and measured ...
Jakubek Delphine - - 2013
Members of the pathogenic Legionella genus encounter suitable growth conditions in nuclear power plant cooling circuits. To limit its proliferation and ensure that levels remain below regulatory thresholds, chemical treatment with monochloramine can be used in continuous or sequential conditions. The aim of this study was to determine the impact ...
Phillipson Lyn - - 2013
The use of respite services by carers has been shown to extend the length of time people with dementia can remain living in the community with family support. However, the use of respite services by informal carers of people with dementia is often low and does not appear to match ...
Panneerselvam Manivel - - 2013
Members of the synuclein family (α, β and γ synucleins) are intrinsically disordered in nature and play a crucial role in the progression of various neurodegenerative disorders and cancers. The association of γSyn with both BubR1 as well as microtubule subunits renders resistance against various anti-cancer drugs. However, the structural ...
Negahban Hossein - - 2013
Abstract Purpose: The aim was to culturally translate and validate the Persian lower extremity functional scale (LEFS) in a heterogeneous sample of outpatients with lower extremity musculoskeletal disorders (n = 304). Method: This is a prospective methodological study. After a standard forward-backward translation, psychometric properties were assessed in terms of test-retest reliability, ...
Zomer Ella - - 2013
BACKGROUND: Individuals with metabolic syndrome (MetS) are at increased risk of cardiovascular disease (CVD), often requiring combination drug therapy for control of risk factors and subsequent risk reduction. This study aims to compare the long-term effectiveness and cost effectiveness of the polypill (a multi-component tablet), and its components (alone or ...
Musilova P - - 2013
Equidae is a small family which comprises horses, African and Asiatic asses, and zebras. Despite equids having diverged quite recently, their karyotypes underwent rapid evolution which resulted in extensive differences among chromosome complements in respective species. Comparative mapping using whole-chromosome painting probes delineated genome-wide chromosome homologies among extant equids, enabling ...
Kang Chaeryon C Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, - - 2013
The bootstrap method for estimating the standard error of the kappa statistic in the presence of clustered data is evaluated. Such data arise, for example, in assessing agreement between physicians and their patients regarding their understanding of the physician-patient interaction and discussions. We propose a computationally efficient procedure for generating ...
Farag N - - 2013
The response to treatment of severe methicillin-resistant Staphylococcus aureus (MRSA) infections with the traditional antibiotics is sometimes unsatisfactory and multiple antibiotic resistance is common. Adjuvant therapy such as intravenous immunoglobulin G (IVIG) could possibly be helpful in the treatment of such infections. The effect of IVIG on the capacity of ...
Spitz Gershon - - 2013
Traumatic brain injury (TBI) frequently results in impairments of memory, speed of information processing, and executive functions that may persist over many years. Diffuse axonal injury is one of the key pathologies following TBI, causing cognitive impairments due to the disruption of cortical white matter pathways. The current study examined ...
Yoneoka Yuichiro - - 2013
BACKGROUND: High-definition imaging in endoscopic transsphenoidal pituitary surgery accounts for significantly better identification of anatomic structures. This report presents the clinical images of the adenohypophysis and neurohypophysis under high-definition endoscopic observation, and provides some clues for pituitary-sparing surgery. METHODS: Ten demonstrative cases of pituitary lesions, including three cases of gonadotropin-producing ...
Katju Vaishali - - 2013
BACKGROUND: Gene duplicates often exhibit asymmetric rates of molecular evolution in their early evolutionary existence. This asymmetry in rates is thought to signify the maintenance of the ancestral function by one copy and the removal of functional constraint on the other copy, enabling it to embark on a novel evolutionary ...
Mazzeo Mina - - 2013
The potential of the phenoxy-thioether moieties as ancillary ligands in the coordination chemistry of group 3 metals was explored. The amine elimination reactions between yttrium and scandium amido precursors {M [N(SiHMe2)2]3 (THF)n} with the proligands {4,6-tBu2-OC6H2-2-CH2S(2-R-C6H4)}H [R = H (), CH3 (), Br (), CF3 ()], bearing different substituents at ...
Redon Josep - - 2013
The accuracy of clinic blood pressure (BP) measurements is limited due to the presence of 24-hour BP variability and white-coat or masked hypertension. In contrast, 24-hour ambulatory BP monitoring (ABPM) has evolved into an accurate and reproducible tool for the assessment and management of hypertension. Various out-of-office measurements can be ...
Offman Elliot - - 2013
BACKGROUND: The fixed-dose combination of aspirin (acetylsalicylic acid) 25 mg plus extended-release dipyridamole 200 mg (ASA + ER-DP) is used for long-term secondary stroke prevention in patients who have experienced non-cardioembolic stroke or transient ischemic attack. Although the theoretical risk is low that the antiplatelet activity of ASA + ER-DP will be affected by concomitant use ...
Houvenaeghel Gilles - - 2013
Micrometastases or sub-micrometastases can be detected by standard histopathological method sometimes associated with immunohistochemistry in lymph nodes, bone marrow and blood. The consequence of these small size involvement may be prognostic and therapeutic. Two factors are necessary to assess this kind of involvement: the rate of involvement of non-sentinel lymph ...
Malmstrom Theodore K - - 2013
Recent efforts to provide a consensus definition propose that sarcopenia be considered a clinical syndrome associated with the loss of both skeletal muscle mass and muscle function that occurs with aging. Validation of sarcopenia definitions that include both low muscle mass and poor muscle function is needed. In the population-based ...
Chesney Dana L - - 2013
Prior knowledge in the domain of mathematics can sometimes interfere with learning and performance in that domain. One of the best examples of this phenomenon is in students' difficulties solving equations with operations on both sides of the equal sign. Elementary school children in the U.S. typically acquire incorrect, operational ...
Bonnì Sonia - - 2013
Recent studies showed that non-invasive brain stimulation methods, such as repetitive transcranial magnetic stimulation (rTMS) can improve the symptoms of neglect in stroke patients. Here, we adopted this approach to improve visuo-spatial deficit in a patient with traumatic brain injury (TBI) that showed important symptoms of visuo-spatial neglect. We found ...
Jesenska Sona - - 2013
Species sensitivity distribution (SSD) is commonly used in prospective risk assessment to derive predicted no-effect concentrations, toxicity exposure ratios, and environmental quality standards for individual chemicals such as pesticides. The application of SSD in the retrospective risk assessment of chemical mixtures at the river basin scale (i.e., the estimation of ...
< 3 4 5 6 7 8 9 10 11 12 13 >