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Results 251 - 300 of 3209
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Reulbach Udo - - 2013
AIM: To explore the association between weight and bullying; considering victims and perpetrators as two aspects of bullying, and subjective perception and objective measurement as two aspects of weight. METHODS: This study is based on the first wave of data collection from Growing Up in Ireland - the National Longitudinal ...
Arjona-Sanchez Alvaro - - 2013
BACKGROUND: Pseudomyxoma peritonei (PMP) is a rare disease with an incidence rate of approximately 1 per million a year. During the past few years, there has been a survival benefit for these patients treated by complete cytoreduction and perioperative chemotherapy. Better survival rates were found in the adenomucinosis group than ...
Mohr Zarah - - 2013
Background: Only the exact pretherapeutical, histopathological diagnosis of non-distinctive soft tissue tumours leads to adequate therapy. Next to the standardized incisional biopsy, current needle biopsy techniques are limited by the small size of the tissue samples and error rate. This study was performed to explore whether the ultrasound-guidance can support ...
Qualls Whitney A - - 2013
The international trade of lucky bamboo (Dracaena sanderiana [Asparagaceae]) is responsible for certain introductions of the exotic species Aedes albopictus (Skuse) in California and the Netherlands. Understanding the association of this species with lucky bamboo and other ornamental plants is important from a public health standpoint. The aim of this ...
Harsch Michael J - - 2013
Two volatile thiols, 3-mercaptohexan-1-ol (3MH) and 3-mercaptohexyl-acetate (3MHA), are key aroma impact compounds in many young white wines, especially of the variety Sauvignon Blanc. Although great effort has been invested to identify their precursors in recent years, the origin of the majority of 3MH and 3MHA generated during wine fermentation ...
Snyder Claire F - - 2013
PURPOSE: Patient-reported outcomes (PROs) are used increasingly for individual patient management. Identifying which PRO scores require a clinician's attention is an ongoing challenge. Previous research used a needs assessment to identify EORTC-QLQ-C30 cutoff scores representing unmet needs. This analysis attempted to replicate the previous findings in a new and larger ...
Virta Jyri J - - 2013
Cardiovascular risk factors increase the risk of dementia in later life. The aims of the current study were to assess the effect of multiple midlife cardiovascular risk factors on the risk of cognitive impairment in later life, and to assess the validity of the previously suggested CAIDE Study risk score ...
Valdes-Sánchez Teresa - - 2013
Spinal cord injury (SCI) is a cause of paralysis. Although some strategies have been proposed to palliate the severity of this condition, so far no effective therapies have been found to reverse it. Recently, we have shown that acute transplantation of ependymal stem/progenitor cells (epSPCs), which are spinal cord-derived neural ...
Khatun Mahfuza - - 2013
BACKGROUND: Research on natural products has gained a wide popularity due to the potential of discovering active compounds. The antioxidant properties contained in plants have been proposed as one of the mechanisms for the observed beneficial effect. Therefore, the present study investigated the antioxidant activity and total phenolic contents of ...
Patterson Julie V - - 2013
Patterson JV, Sandman CA, Jin Y, Kemp AS, Potkin SG, Bunney WE Jr. Gating of a novel brain potential is associated with perceptual anomalies in bipolar disorder. Bipolar Disord 2013: 00: 000-000. © 2013 John Wiley & Sons A/S.Published by Blackwell Publishing Ltd. Objectives:  Our laboratory recently identified the P85 ...
Morente-Sánchez Jaime - - 2013
Doping in sport is a well-known phenomenon that has been studied mainly from a biomedical point of view, even though psychosocial approaches are also key factors in the fight against doping. This phenomenon has evolved greatly in recent years, and greater understanding of it is essential for developing efficient prevention ...
Fukudo Masahide - - 2013
BACKGROUND: Erlotinib shows large inter-patient pharmacokinetic variability, but the impact of early drug exposure and genetic variations on the clinical outcomes of erlotinib remains fully investigated. The primary objective of this study was to clarify the population pharmacokinetics/pharmacodynamics of erlotinib in Japanese patients with non-small cell lung cancer (NSCLC). The ...
McGee Richard G - - 2013
AIM: Systematic reviews have the potential to map those areas where children are under-represented in surgical research. We aimed to describe and evaluate the quantity, coverage and the quality of conduct and reporting of systematic reviews of surgical procedures in children. METHODS: We searched four biomedical databases, a systematic review ...
Arampatzis Spyridon - - 2013
BACKGROUND: Diuretics are among the most commonly prescribed medications and, due to their mechanisms of action, electrolyte disorders are common side effects of their use. In the present work we investigated the associations between diuretics being taken and the prevalence of electrolyte disorders on admission as well as the impact ...
Xin Bingjing - - 2013
A copper(i) halide-based compound with a formula of [Cu4I3(DABCO)2]I3 (DABCO = N,N'-dimethyl-1,4-diazabicyclo[2.2.2]octane) has been prepared by solvothermal reactions. This compound has been characterized by single-crystal X-ray diffraction, elemental analysis, IR, TG, XPS and powder X-ray diffractions. Structure analyses reveal that this compound is constructed by unprecedented cationic cluster [Cu8I6](2+) and ...
de Rooij J D E - - 2013
Cytogenetic abnormalities and early response to treatment are the main prognostic factors in acute myeloid leukemia (AML). Recently, NUP98/NSD1, a cytogenetically cryptic fusion, was described as recurrent event in AML, characterized by dismal prognosis and HOXA/B-gene overexpression. Using split-signal FISH, other NUP98-rearranged pediatric AML cases were identified, including several acute ...
Zacharaki Dimitra - - 2013
Extensive experimental studies indicate that autologous bone marrow mesenchymal stem cells (BMSCs) are able to ameliorate experimental autoimmune encephalomyelitis (EAE) and potentially multiple sclerosis. However, the impact that the inflammatory environment present in EAE may have on the biological properties of BMSCs expanded in vitro for transplantation is yet to ...
Mourouzis Iordanis - - 2013
Thyroid hormone receptor α1 (TRα1) is shown to be critical for the maturation of cardiomyocytes and for the cellular response to stress. TRα1 is altered during post ischemic cardiac remodeling but the physiological significance of this response is not fully understood. Thus, the present study explored the potential consequences of ...
Yang Yang - - 2013
We report a scaffold-free approach in which four- and six-helix DNA bundle units, assembled from a small number of single stranded DNA oligonucleotides precisely arranged in networks of contiguous and semi-crossover strands, are connected into DNA nano rings. Nearly uniform structures with well-defined diameters of 53 ± 7 nm, 81 ...
Gee Michelle L - - 2013
Antimicrobial peptides hold promise as broad-spectrum alternatives to conventional antibiotics. The mechanism of action of this class of peptide is a topical area of research focused predominantly on their interaction with artificial membranes. Here we compare the interaction mechanism of a model antimicrobial peptide with single artificial membranes and live ...
Daniels V - - 2013
BACKGROUND AND PURPOSE: Synaptic vesicle protein 2A (SV2A) is the specific binding site of the anti-epileptic drug levetiracetam (LEV) and its higher affinity analogue UCB30889. Moreover, the protein has been well validated as a target for anticonvulsant therapy. Here, we report the identification of UCB1244283 acting as a SV2A positive ...
Aguirre-Sierra Arantxa - - 2013
Laboratory experiments were performed to examine the toxic effects of fluoride (F(-)) on the survival and behavior of white-clawed crayfish (Austropotamobius pallipes). Body fluoride contents (bioaccumulation) of test crayfish were also examined. No significant differences between male and female crayfish regarding mortality, escape (tail-flip) response, and fluoride bioaccumulation were detected. ...
Govey Peter M - - 2013
Bone adaptation to its mechanical environment, from embryonic through adult life, is thought to be the product of increased osteoblastic differentiation from mesenchymal stem cells. In parallel with tissue-scale loading, these heterogeneous populations of multipotent stem cells are subject to a variety of biophysical cues within their native microenvironments. Bone ...
Leavy B - - 2013
We investigated the effects of socio-demographic and health factors on timing and location of hip fracture among 484 subjects. Time of fracture varied between community dwellers and residential care facility dwellers, and in relation to subjects' psychotropic drug status. Indoor hip fracture incidence increased on snow-covered days. INTRODUCTION: This paper ...
Qi Xiao-Ni - - 2013
Composite porous scaffolds have attracted extensive attention in the biomedical materials field. The aim of this research was to prepare a novel tri-component composite porous scaffold and to evaluate its relevant properties. The porous scaffold was composed of chitosan (CS), silk fibroin (SF) and nanohydroxyapatite particles (nHA), which we named ...
Pacetti Deborah - - 2013
The total fatty acid composition, especially the furan fatty acid (F-acids) profile, from edible muscle (fillet) and organ tissues (brain, eye, ovaries and testes) of spawning and non-spawning sardine and anchovy were examined. The spawning season had no effect on F-acids profiles of the fillet and all organ tissues, for ...
Li Qinghua - - 2013
S-adenosylhomocysteine hydrolase (SAHH) is an enzyme, which catalyzes the hydrolysis of S-adenosylhomocysteine (SAH) which is formed after the donation of the methyl group of S-adenosylmethionine (SAM) to a methyl acceptor in methylation reaction. As a potent regulator of methylation, SAHH plays a critical role in methylation reaction in the cells. ...
Thomaidis Thomas - - 2013
BACKGROUND: The impact of erythropoiesis-stimulating agents in chemotherapy-induced anemia has been a constant topic of debate over recent years. We prospectively assessed the efficacy of epoetin beta (Epo-b) in improving hemoglobin (Hb) levels and outcome in patients within an open label, randomized clinical phase II trial with advanced or metastatic ...
Kocher Agnes - - 2013
BACKGROUND: Skin and mucosal manifestations such as skin thickening, pruritus, reduced microvascular circulation, digital lesions, appearance-related changes, and dryness of the eyes and mucosa are common in systemic sclerosis (SSc). A specific skin and mucosa care education programme for patients and their family caregivers should increase their self-efficacy and improve ...
Tahmasebi Farnaz C - - 2013
Brain metastasis from papillary thyroid carcinoma (PTC) is extremely rare and carries a poor prognosis. We report nine cases (five females and four males) of brain metastasis of PTC. The age of patients ranged from 46 to 87 years old. The patients presented with nonspecific symptoms such as headaches. Brain metastasis ...
Webb Kimberly M - - 2013
Ionizing radiation (IR) is of particular interest in biology because its exposure results in severe oxidative stress to the cell's macromolecules. Our recent work with extremophiles supports the idea that IR resistance is most likely achieved by a metabolic route, effected by manganese (Mn) antioxidants. Biochemical analysis of "super-IR resistant" ...
Xia Bing - - 2013
Non-target screening of veterinary drugs using tandem mass spectrometric data was performed on the SmartMass platform. This newly developed software uses the characteristic fragmentation patterns (CFP) to identify chemicals, especially those containing particular substructures. A mixture of 17 sulfonamides was separated by ultra performance liquid chromatography (UPLC), and SmartMass was ...
Mühl Heiko - - 2013
Interleukin (IL)-22, a member of the IL-10 cytokine family, has recently gained significant attention as protective principle in murine models of diseases driven by epithelial injury. Alike its biochemical and functional sibling IL-10, IL-22 elicits cellular activation primarily by engaging the signal transducer and activator of transcription (STAT)-3 track of ...
Sakamoto Nobuo - - 2013
Tenascin-C, a large oligometric glycoprotein of the extracellular matrix, increases the expression of matrix metalloproteinases that lead to plaque instability and rupture, resulting in acute coronary syndrome (ACS). We hypothesized that a high serum tenascin-C level is associated with plaque rupture in patients with ACS. Fifty-two consecutive ACS patients who ...
Yamamoto Yasuhiro - - 2013
The purpose of this study was to examine the usefulness of cross-table view in the clinical diagnosis of cam-type femoroacetabular impingement (FAI). We measured the α angles on radiographs taken in cross-table lateral view in 39 hips with cam-type FAI and compared with those measured in 45 control hips. Alpha ...
Sheldon Roger A - - 2013
In this tutorial review, an overview of the why, what and how of enzyme immobilisation for use in biocatalysis is presented. The importance of biocatalysis in the context of green and sustainable chemicals manufacture is discussed and the necessity for immobilisation of enzymes as a key enabling technology for practical ...
Deenadayalan Anbarasu - - 2013
BACKGROUND: Tuberculosis remains the foremost cause of morbidity and mortality, more than any other single infectious disease in the world. Cell mediated immune response plays a crucial role in the control of tuberculosis. Therefore, measuring cell mediated immune response against the antigens is having a vital role in understanding the ...
Hsu P L - - 2013
BACKGROUND AND PURPOSE: Many organs suffer from ischemic injuries that reduce the ability to generate sufficient energy, which is required for functional maintenance and repair. Erythropoietin (EPO) has the potential to ameliorate ischemic tissue by pleiotropic effects. The aim of this study was to investigate a small molecule EH-201 (2,3,5,4'-tetrahydroxystilbene-2-o-beta-d-glucoside, ...
Drüsedau Marion - - 2013
Preimplantation Genetic Diagnosis (PGD) is a method of testing in vitro embryos as an alternative to prenatal diagnosis with possible termination of pregnancy in case of an affected child. Recently, PGD for hereditary breast and ovarian cancer caused by BRCA1 and BRCA2 mutations has found its way in specialized labs. ...
Akhtar M S - - 2013
A 30-day acclimation trial was conducted using Tor putitora to elucidate its thermal tolerance, oxygen consumption, haemato-biochemical variables and selected enzymatic activities at five acclimation temperatures (AT). Juveniles of T. putitora were randomly distributed among five treatment groups (20, 23, 26, 29 and 32 ± 0.5 °C). There was a significant curvilinear increase ...
Krautz C - - 2013
AIMS/HYPOTHESIS: Immunosuppressive drugs used in human islet transplantation interfere with the balance between beta cell renewal and death, and thus may contribute to progressive graft dysfunction. We analysed the influence of immunosuppressants on the proliferation of transplanted alpha and beta cells after syngeneic islet transplantation in streptozotocin-induced diabetic mice. METHODS: ...
Poritz Lisa S - - 2013
INTRODUCTION: Bacteria have been implicated in the development of pouchitis after ileal pouch anal anastomosis. The change in gastric pH with the use of proton pump inhibitors and H2 antagonists may lead to alteration of enteric bacteria. We hypothesized that chronic use of these medications would decrease the incidence of ...
Zbroch Edyta - - 2013
Background: hRenalase may degrade catecholamines and regulate sympathetic tone and blood pressure (BP). The aim of the study was to assess dopamine (DA), norepinephrine (NE), and renalase in 75 hemodialysis (HD) and 26 peritoneal dialysis (PD) patients and their correlations with heart rate (HR), BP, a type of hypotensive therapy, ...
Dethlefsen Christine - - 2013
Chronic low-grade inflammation plays an important role in the pathogenesis of several cancer forms including breast cancer. The pleiotropic cytokine IL-6 is a key player in systemic inflammation, regulating both the inflammatory response and tissue metabolism during acute stimulations. Here, we review the associations between IL-6 and breast cancer ranging ...
Anouti Mérièm - - 2013
This study describes the use of the pyrrolidinium nitrate ([Pyrr][NO3]) protic ionic liquid (PIL) in a mixture with gamma butyrolactone (γ-BL) as an electrolyte for carbon-based supercapacitors with an operating voltage of 2.0 V and at very low temperature. Thermal and transport properties of this electrolyte were firstly evaluated from ...
Cho Jung Sang - - 2013
The effect of chloride-substitution on bioactivity and osteoconductivity of hydroxyapatite (OHAp) was newly investigated. Chloride-substituted hydroxyapatites (ClAp) with low and high chloride concentrations were synthesized by reacting Ca(OH)2 and H3 PO4 with NH4 Cl of low and high concentrations, with subsequent sintering. As a control, pure OHAp was prepared under ...
Compson Zacchaeus G - - 2013
Reciprocal subsidies between rivers and terrestrial habitats are common where terrestrial leaf litter provides energy to aquatic invertebrates while emerging aquatic insects provide energy to terrestrial predators (e.g., birds, lizards, spiders). We examined how aquatic insect emergence changed seasonally with litter from two foundation riparian trees, whose litter often dominates ...
Xu Helen - - 2013
PURPOSE: To assess retrospectively the clinical accuracy of an magnetic resonance imaging-guided robotic prostate biopsy system that has been used in the US National Cancer Institute for over 6 years. METHODS: Series of 2D transverse volumetric MR image slices of the prostate both pre (high-resolution T2-weighted)- and post (low-resolution)- needle ...
Tengstam Sven - - 2013
It is often assumed that disability reduces the marginal utility of income. In this article, individuals' marginal utility of income in two states-(i) paralyzed in both legs from birth and (ii) not mobility impaired at all-is measured through hypothetical choices between imagined lotteries behind a so-called veil of ignorance. The ...
Mikesch Jan-Henrik - - 2013
High-dose chemotherapy (HDT) followed by autologous stem cell transplantation (ASCT) is considered standard in the treatment of patients with relapsed or refractory aggressive peripheral T cell lymphoma (PTCL). However, the optimal salvage regimen before ASCT has not yet been established. We retrospectively analyzed 31 patients with relapsed or refractory aggressive ...
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