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Results 201 - 250 of 3210
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Ujszaszi Akos - - 2013
Red cell distribution width (RDW), a measure of heterogeneity in the size of circulating erythrocytes, reportedly predicts mortality. Similarly to RDW, impaired renal function is also associated with inflammation and protein-energy wasting. This study assessed if renal function is associated with RDW independent of relevant confounders in stable kidney transplant ...
Ast Tslil - - 2013
Abstract Translocation into the endoplasmic reticulum (ER) is the first biogenesis step for hundreds of eukaryotic secretome proteins. Over the past 30 years, groundbreaking biochemical, structural and genetic studies have delineated one conserved pathway that enables ER translocation- the signal recognition particle (SRP) pathway. However, it is clear that this ...
Kim Sae-Mi - - 2013
Magnesium and its alloys are candidate materials for biodegradable implants; however, excessively rapid corrosion behavior restricts their practical uses in biological systems. For such applications, surface modification is essential, and the use of anticorrosion coatings is considered as a promising avenue. In this study, we coated Mg with hydroxyapatite (HA) ...
Sweetlove Lee J - - 2013
Respiration is a major contributor to net exchange of CO2 between plants and the atmosphere and thus an important aspect of the vegetation component of global climate change models. However, a mechanistic model of respiration is lacking and so here we explore the potential for flux balance analysis (FBA) to ...
Ze Yuguan - - 2013
Titanium dioxide nanoparticules (TiO2 NPs) are widely used in toothpastes, sunscreens and products for cosmetic purpose that the human employ daily. While the neurotoxicity induced by TiO2 NPs has been demonstrated, very little is known about the molecular mechanisms underlying the brain cognition and behavioral injury. In this study, mice ...
Telzer Eva H - - 2013
Adolescent substance use is one of today's most important social concerns, with Latino youth exhibiting the highest overall rates of substance use. Recognizing the particular importance of family connection and support for families from Mexican backgrounds, the current study seeks to examine how family obligation values and family assistance behaviors ...
Li Shan - - 2013
To investigate the role of miR-215 in the relapse following radical surgery of colorectal cancer patients. The clinical data and surgical frozen tumor tissues were retrospectively collected from 125 stage II/III colorectal cancer patients, which contained 60 patients who relapsed and 65 patients who did not relapse within 3 years after ...
Deneo-Pellegrini Hugo - - 2013
OBJECTIVE: The aim of this study was to investigate the association between nutrient-based dietary patterns and squamous cell cancers of the head and neck. METHODS: We used a case-control study which included 548 cases and 548 controls. From these participants, we derived 23 nutrients and they were then submitted to ...
Salgado-Maldonado Guillermo - - 2013
A redescription of Neoechinorhynchus (Neoechinorhynchus) golvani Salgado-Maldonado (An Inst Biol Univ Nal Autón Méx, Ser Zool 49:35-47, 1978) is presented, based on adult specimens collected from the type host Paraneetroplus fenestratus from the type location, the Lago de Catemaco lake, Veracruz state, Mexico, and its presence is recorded in other ...
Yang Miao - - 2013
A new chiral copper borophosphate, LiCu2[BP2O8(OH)2] (), was crystallized from achiral inorganic raw materials in boric acid flux reaction. The structure features a 9-ring channel enclosed by triple right-handed helices. The bulk sample exhibits optical activity confirmed by circular dichroism (CD) spectra, indicating an interesting spontaneous resolution phenomenon.
Huppelschoten Aleida G - - 2013
OBJECTIVE: To study the effect of subcutaneous tissue closing and the effect of two different skin closure methods at cesarean section on long-term cosmetic results. DESIGN: Randomized controlled trial. SETTING: A large teaching hospital in the Netherlands. POPULATION: Women undergoing a cesarean section. METHODS: Women undergoing a cesarean section were ...
Abdolahpur Monikh Fazel - - 2013
The concentration of heavy metals was determined in tissues of sole (Euryglossa orientalis), mullet (Liza abu) and croacker fish (Johnius belangerii) from Musa estuary. Generally, the highest concentration of the studied metals in the three species was found in the liver tissue. The levels of Cd and Cu in fish ...
Sohal Davendra P S - - 2013
PURPOSE: Platinum compounds or bevacizumab, in combination with gemcitabine, achieved good response rates in early studies in advanced pancreatic cancer. This prompted an evaluation of an aggressive approach to allow better local control and resectability in locally advanced disease. METHODS: We piloted a combination of gemcitabine/oxaliplatin/bevacizumab Q2w for four cycles, ...
Baeva Larissa F - - 2013
This study examined the effect of HA molecular weight on immune response. HA with molecular weights ranging from the unitary disaccharide unit (400 Dalton) up to 1.7x10(6) Dalton and with very low endotoxin contamination level (less than 0.03 EU/mg) was used. Primary human monocyte/macrophage cultures were assayed for IL-1β production ...
Reulbach Udo - - 2013
AIM: To explore the association between weight and bullying; considering victims and perpetrators as two aspects of bullying, and subjective perception and objective measurement as two aspects of weight. METHODS: This study is based on the first wave of data collection from Growing Up in Ireland - the National Longitudinal ...
Arjona-Sanchez Alvaro - - 2013
BACKGROUND: Pseudomyxoma peritonei (PMP) is a rare disease with an incidence rate of approximately 1 per million a year. During the past few years, there has been a survival benefit for these patients treated by complete cytoreduction and perioperative chemotherapy. Better survival rates were found in the adenomucinosis group than ...
Mohr Zarah - - 2013
Background: Only the exact pretherapeutical, histopathological diagnosis of non-distinctive soft tissue tumours leads to adequate therapy. Next to the standardized incisional biopsy, current needle biopsy techniques are limited by the small size of the tissue samples and error rate. This study was performed to explore whether the ultrasound-guidance can support ...
Qualls Whitney A - - 2013
The international trade of lucky bamboo (Dracaena sanderiana [Asparagaceae]) is responsible for certain introductions of the exotic species Aedes albopictus (Skuse) in California and the Netherlands. Understanding the association of this species with lucky bamboo and other ornamental plants is important from a public health standpoint. The aim of this ...
Harsch Michael J - - 2013
Two volatile thiols, 3-mercaptohexan-1-ol (3MH) and 3-mercaptohexyl-acetate (3MHA), are key aroma impact compounds in many young white wines, especially of the variety Sauvignon Blanc. Although great effort has been invested to identify their precursors in recent years, the origin of the majority of 3MH and 3MHA generated during wine fermentation ...
Snyder Claire F - - 2013
PURPOSE: Patient-reported outcomes (PROs) are used increasingly for individual patient management. Identifying which PRO scores require a clinician's attention is an ongoing challenge. Previous research used a needs assessment to identify EORTC-QLQ-C30 cutoff scores representing unmet needs. This analysis attempted to replicate the previous findings in a new and larger ...
Virta Jyri J - - 2013
Cardiovascular risk factors increase the risk of dementia in later life. The aims of the current study were to assess the effect of multiple midlife cardiovascular risk factors on the risk of cognitive impairment in later life, and to assess the validity of the previously suggested CAIDE Study risk score ...
Parker Jennifer - - 2013
Genetic and microarray analyses have provided useful information in the area of plant and pathogen interactions. Pseudomonas syringae pv. tomato DC3000 (Pst) causes bacterial speck disease in tomato. Previous studies have shown that changes in response to pathogen infection at transcript level are variable at different time points. This study ...
Valdes-Sánchez Teresa - - 2013
Spinal cord injury (SCI) is a cause of paralysis. Although some strategies have been proposed to palliate the severity of this condition, so far no effective therapies have been found to reverse it. Recently, we have shown that acute transplantation of ependymal stem/progenitor cells (epSPCs), which are spinal cord-derived neural ...
Diaz-Ledezma Claudio - - 2013
BACKGROUND: Currently, three surgical approaches are available for the treatment of cam femoroacetabular impingement (FAI), namely surgical hip dislocation (SHD), hip arthroscopy (HA), and the miniopen anterior approach of the hip (MO). Although previous systematic reviews have compared these different approaches, an overall assessment of their performance is not available. ...
Khatun Mahfuza - - 2013
BACKGROUND: Research on natural products has gained a wide popularity due to the potential of discovering active compounds. The antioxidant properties contained in plants have been proposed as one of the mechanisms for the observed beneficial effect. Therefore, the present study investigated the antioxidant activity and total phenolic contents of ...
Patterson Julie V - - 2013
Patterson JV, Sandman CA, Jin Y, Kemp AS, Potkin SG, Bunney WE Jr. Gating of a novel brain potential is associated with perceptual anomalies in bipolar disorder. Bipolar Disord 2013: 00: 000-000. © 2013 John Wiley & Sons A/S.Published by Blackwell Publishing Ltd. Objectives:  Our laboratory recently identified the P85 ...
Morente-Sánchez Jaime - - 2013
Doping in sport is a well-known phenomenon that has been studied mainly from a biomedical point of view, even though psychosocial approaches are also key factors in the fight against doping. This phenomenon has evolved greatly in recent years, and greater understanding of it is essential for developing efficient prevention ...
Fukudo Masahide - - 2013
BACKGROUND: Erlotinib shows large inter-patient pharmacokinetic variability, but the impact of early drug exposure and genetic variations on the clinical outcomes of erlotinib remains fully investigated. The primary objective of this study was to clarify the population pharmacokinetics/pharmacodynamics of erlotinib in Japanese patients with non-small cell lung cancer (NSCLC). The ...
Altenburg Josje - - 2013
Macrolide antibiotics have been shown beneficial in cystic fibrosis (CF) and diffuse panbronchiolitis, and earlier findings also suggest a benefit in non-CF bronchiectasis. To determine the efficacy of macrolide maintenance treatment for adults with non-CF bronchiectasis. The BAT (Bronchiectasis and Long-term Azithromycin Treatment) study, a randomized, double-blind, placebo-controlled trial conducted ...
McGee Richard G - - 2013
AIM: Systematic reviews have the potential to map those areas where children are under-represented in surgical research. We aimed to describe and evaluate the quantity, coverage and the quality of conduct and reporting of systematic reviews of surgical procedures in children. METHODS: We searched four biomedical databases, a systematic review ...
Arampatzis Spyridon - - 2013
BACKGROUND: Diuretics are among the most commonly prescribed medications and, due to their mechanisms of action, electrolyte disorders are common side effects of their use. In the present work we investigated the associations between diuretics being taken and the prevalence of electrolyte disorders on admission as well as the impact ...
Xin Bingjing - - 2013
A copper(i) halide-based compound with a formula of [Cu4I3(DABCO)2]I3 (DABCO = N,N'-dimethyl-1,4-diazabicyclo[2.2.2]octane) has been prepared by solvothermal reactions. This compound has been characterized by single-crystal X-ray diffraction, elemental analysis, IR, TG, XPS and powder X-ray diffractions. Structure analyses reveal that this compound is constructed by unprecedented cationic cluster [Cu8I6](2+) and ...
de Rooij J D E - - 2013
Cytogenetic abnormalities and early response to treatment are the main prognostic factors in acute myeloid leukemia (AML). Recently, NUP98/NSD1, a cytogenetically cryptic fusion, was described as recurrent event in AML, characterized by dismal prognosis and HOXA/B-gene overexpression. Using split-signal FISH, other NUP98-rearranged pediatric AML cases were identified, including several acute ...
Zacharaki Dimitra - - 2013
Extensive experimental studies indicate that autologous bone marrow mesenchymal stem cells (BMSCs) are able to ameliorate experimental autoimmune encephalomyelitis (EAE) and potentially multiple sclerosis. However, the impact that the inflammatory environment present in EAE may have on the biological properties of BMSCs expanded in vitro for transplantation is yet to ...
Mourouzis Iordanis - - 2013
Thyroid hormone receptor α1 (TRα1) is shown to be critical for the maturation of cardiomyocytes and for the cellular response to stress. TRα1 is altered during post ischemic cardiac remodeling but the physiological significance of this response is not fully understood. Thus, the present study explored the potential consequences of ...
Yang Yang - - 2013
We report a scaffold-free approach in which four- and six-helix DNA bundle units, assembled from a small number of single stranded DNA oligonucleotides precisely arranged in networks of contiguous and semi-crossover strands, are connected into DNA nano rings. Nearly uniform structures with well-defined diameters of 53 ± 7 nm, 81 ...
Gee Michelle L - - 2013
Antimicrobial peptides hold promise as broad-spectrum alternatives to conventional antibiotics. The mechanism of action of this class of peptide is a topical area of research focused predominantly on their interaction with artificial membranes. Here we compare the interaction mechanism of a model antimicrobial peptide with single artificial membranes and live ...
Daniels V - - 2013
BACKGROUND AND PURPOSE: Synaptic vesicle protein 2A (SV2A) is the specific binding site of the anti-epileptic drug levetiracetam (LEV) and its higher affinity analogue UCB30889. Moreover, the protein has been well validated as a target for anticonvulsant therapy. Here, we report the identification of UCB1244283 acting as a SV2A positive ...
Aguirre-Sierra Arantxa - - 2013
Laboratory experiments were performed to examine the toxic effects of fluoride (F(-)) on the survival and behavior of white-clawed crayfish (Austropotamobius pallipes). Body fluoride contents (bioaccumulation) of test crayfish were also examined. No significant differences between male and female crayfish regarding mortality, escape (tail-flip) response, and fluoride bioaccumulation were detected. ...
Govey Peter M - - 2013
Bone adaptation to its mechanical environment, from embryonic through adult life, is thought to be the product of increased osteoblastic differentiation from mesenchymal stem cells. In parallel with tissue-scale loading, these heterogeneous populations of multipotent stem cells are subject to a variety of biophysical cues within their native microenvironments. Bone ...
Dumas Jerald E - - 2013
Cysteine cathepsins are a family of proteases identified in cancer, atherosclerosis, osteoporosis, arthritis, and a number of other diseases. As this number continues to rise, so does the need for low cost, broad use quantitative assays to detect their activity and can be translated to the clinic in the hospital ...
Leavy B - - 2013
We investigated the effects of socio-demographic and health factors on timing and location of hip fracture among 484 subjects. Time of fracture varied between community dwellers and residential care facility dwellers, and in relation to subjects' psychotropic drug status. Indoor hip fracture incidence increased on snow-covered days. INTRODUCTION: This paper ...
Qi Xiao-Ni - - 2013
Composite porous scaffolds have attracted extensive attention in the biomedical materials field. The aim of this research was to prepare a novel tri-component composite porous scaffold and to evaluate its relevant properties. The porous scaffold was composed of chitosan (CS), silk fibroin (SF) and nanohydroxyapatite particles (nHA), which we named ...
Pacetti Deborah - - 2013
The total fatty acid composition, especially the furan fatty acid (F-acids) profile, from edible muscle (fillet) and organ tissues (brain, eye, ovaries and testes) of spawning and non-spawning sardine and anchovy were examined. The spawning season had no effect on F-acids profiles of the fillet and all organ tissues, for ...
Li Qinghua - - 2013
S-adenosylhomocysteine hydrolase (SAHH) is an enzyme, which catalyzes the hydrolysis of S-adenosylhomocysteine (SAH) which is formed after the donation of the methyl group of S-adenosylmethionine (SAM) to a methyl acceptor in methylation reaction. As a potent regulator of methylation, SAHH plays a critical role in methylation reaction in the cells. ...
Thomaidis Thomas - - 2013
BACKGROUND: The impact of erythropoiesis-stimulating agents in chemotherapy-induced anemia has been a constant topic of debate over recent years. We prospectively assessed the efficacy of epoetin beta (Epo-b) in improving hemoglobin (Hb) levels and outcome in patients within an open label, randomized clinical phase II trial with advanced or metastatic ...
Kocher Agnes - - 2013
BACKGROUND: Skin and mucosal manifestations such as skin thickening, pruritus, reduced microvascular circulation, digital lesions, appearance-related changes, and dryness of the eyes and mucosa are common in systemic sclerosis (SSc). A specific skin and mucosa care education programme for patients and their family caregivers should increase their self-efficacy and improve ...
Tahmasebi Farnaz C - - 2013
Brain metastasis from papillary thyroid carcinoma (PTC) is extremely rare and carries a poor prognosis. We report nine cases (five females and four males) of brain metastasis of PTC. The age of patients ranged from 46 to 87 years old. The patients presented with nonspecific symptoms such as headaches. Brain metastasis ...
Webb Kimberly M - - 2013
Ionizing radiation (IR) is of particular interest in biology because its exposure results in severe oxidative stress to the cell's macromolecules. Our recent work with extremophiles supports the idea that IR resistance is most likely achieved by a metabolic route, effected by manganese (Mn) antioxidants. Biochemical analysis of "super-IR resistant" ...
Xia Bing - - 2013
Non-target screening of veterinary drugs using tandem mass spectrometric data was performed on the SmartMass platform. This newly developed software uses the characteristic fragmentation patterns (CFP) to identify chemicals, especially those containing particular substructures. A mixture of 17 sulfonamides was separated by ultra performance liquid chromatography (UPLC), and SmartMass was ...
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