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Results 451 - 500 of 3210
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Cai Gang - - 2013
BACKGROUND: T cell antiviral function is impaired during chronic hepatitis B (CHB). Programmed death-1 (PD-1) impairs antiviral T cell responses, but dysfunction is not always reversed by blockade of PD-1 pathway. Whether distinct T cell populations expressing different sets of inhibitory molecules exist has not been determined. METHODS: We studied ...
Zamani F - - 2013
Since spinal cord injury is a complicated problem, neural tissue repair and regeneration strategies have received a great deal of attention. In this study, a 3D nanofibrous core-sheath scaffold with nanorough sheath and aligned core were fabricated by a combined electrospinning method with water vortex and two-nozzle system. In-vitro and ...
Alencar Allan K N - - 2013
BACKGROUND AND PURPOSE: Pulmonary hypertension is characterized by enhanced pulmonary vascular resistance, right ventricular hypertrophy, and increased right ventricular systolic pressure. Here, we investigated the effects of a N-acylhydrazone derivative, 3,4-dimethoxyphenyl-N-methyl-benzoilidrazide (LASSBio-1359), on the therapeutic treatment of monocrotaline induced pulmonary hypertension in rats. EXPERIMENTAL APPROACH: Male Wistar rats were divided ...
Song Xiaolu - - 2013
Deprotonation of functional salicylaldimines with NaH invariably results in cubane or double-cubane Na(i) aggregates which transmetallate with Ni(ii) under different stoichiometric conditions to give Ni(ii) complexes that are catalytically active towards ethylene oligomerisation.
Demir Tuğçe - - 2013
Total of 171 alkaliphilic actinomycetes were evaluated for extracellular RNase production and Streptomyces sp. M49-1 was selected for further experiments. Fermentation optimization for RNase production was implemented in two steps using response surface methodology with central composite design. In the first step, the effect of independent fermentation variables including temperature, ...
Matias Ambrocio Melvin A - - 2013
Integration of genetic connectivity information in effective marine reserve (MR) design is important in sustaining marine biodiversity. Here, genetic connectivity based on mitochondrial DNA (mtDNA) of three reef fish species, namely Epinephelus merra (n = 67; 32 from Bolinao, 14 from Alaminos, and 21 from Masinloc), Parupeneus multifasciatus (n = 23; 12 from Bolinao ...
Shellaiah Muthaiah - - 2013
Simple pyridyl-salicylimine derivatives (, and ) are reported for the first time as fluorescence "turn-on" sensors for distinct detections of Zn(2+), Al(3+) and OH(-) ions in mixed-aqueous media CH3CN/H2O with volume ratios of 6/4 and 3/7 (at pH = 7 and 25 °C) via internal charge transfer (ICT), chelation enhanced ...
Upshaw Jenica - - 2013
The aging population and an epidemic of heart failure have led to an increasing volume of noncardiac surgical procedures being performed in patients with heart failure. Knowledge pertaining to perioperative risk stratification and management among this diverse and complex cohort of patients has therefore become increasingly important. Most available data ...
Moiseyenko Vladimir M - - 2013
Sensitivity of gastric cancer (GC) to conventional cytotoxic therapy may be at least in part attributed to molecular features of the tumor cells. We analyzed all patients with metastatic GC treated in the N.N. Petrov Institute of Oncology (St. Petersburg) within years 1999-2010 and identified 65 cases with evaluable treatment ...
Oelgiesser Dan - - 2013
Objective: To report a multidisciplinary treatment of gemination/fusion of the left maxillary first incisor. Case Report: An 11-year-old boy presented to our clinic with the chief complaint of an unpleasant appearance of his anterior teeth. Clinical and radiographic evaluation revealed gemination/fusion of the left maxillary first incisor combined with an ...
Gerhardt Andrea - - 2013
The risk of premature manifestation of cardiovascular disease is higher in women after a maternal placental syndrome, especially with a history of fetal IUGR. Aim of the study was to assess hereditary risk factors for arterial thrombosis as risk factors for IUGR. 183 women with fetal IUGR birth weight below ...
Ren Fuzeng - - 2013
A combined experimental and computational approach was employed to investigate the feasibility and effectiveness of characterizing carbonated apatite (CAp) by infrared (IR) spectroscopy. First, an experimental comparative study was conducted to identify characteristic IR vibrational bands of carbonate substitution in the apatite lattice. The IR spectra of pure hydroxyapatite (HA), ...
Filiberti Rosa - - 2013
CYFRA 21-1 and CEA have been applied for the differential diagnosis of malignant pleural mesothelioma (MPM). The soluble mesothelin-related peptide (SMRP) has been proposed as a specific marker for distinguishing MPM from benign diseases and other malignancies in pleural effusions (PEs). In this study, we evaluated the usefulness of SMRP ...
Müggler Simon A - - 2013
We admitted a 42 year old woman with clinical signs of shock, coma, and ecg changes consistent with a ST elevation myocardial infarction to percutaneous coronary intervention. Normal coronary arteries were found. Due to the comatose state a cranial computed tomography scan was performed, where a subarachnoid hemorrhage was detected. ...
Wang Yanping - - 2013
Various factors can affect the functions of dental pulp stem cells (DPSCs). However, little knowledge is available about the effects of estrogen deficiency on the differentiation of DPSCs. In this study, an estrogen-deficient rat model was constructed and multi-colony-derived DPSCs were obtained from the incisors of ovariectomized (OVX) or sham-operated ...
Steffan Jean - - 2013
BACKGROUND: Little information is available on the ciclosporin dose-tapering regimen and clinical response in the treatment of feline hypersensitivity dermatitis. HYPOTHESIS/OBJECTIVES: To test a dose-tapering regimen and assess efficacy and clinical safety for up to 18 weeks. ANIMALS: Eighty-eight client-owned cats with feline hypersensitivity dermatitis. METHODS: Cats that received either a ...
Flessa Fabienne - - 2013
Restriction fragment length polymorphism tools is an R application which supports a complete workflow of polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP), dealing with the problems which accompany analysis when PCR-RFLP is used in diversity studies. Large numbers of different RFLP samples obtained from multiple electrophoresis runs might lead to ...
Stoloff Kevin - - 2013
Men who have sex with men (MSM) have a higher prevalence of common mental disorders (CMD), as compared with heterosexual men. HIV infection is independently associated with higher rates of CMD. Given this context, and the high background community prevalence of HIV in South Africa, MSM are at even greater ...
Pitchers W R - - 2013
Phenotypic integration and plasticity are central to our understanding of how complex phenotypic traits evolve. Evolutionary change in complex quantitative traits can be predicted using the multivariate breeders' equation, but such predictions are only accurate if the matrices involved are stable over evolutionary time. Recent study, however, suggests that these ...
Pan Min - - 2013
Uniparental disomy (UPD) is an uncommon chromosome condition, but UPD involving chromosome 21 is rarely reported. We reported here a case who had first trimester screening test for Down syndrome, chorionic villus sampling for fetal karyotyping, quantitative fluorescence polymerase chain reaction (QF-PCR), as well as non-invasive prenatal testing (NIPT) by ...
Muggia Lucia - - 2013
Development of characteristic thallus structures in lichen-forming fungi requires the association with suitable photoautotrophic partners. Previous work suggests that fungi have a specific range of compatible photobionts and that selected algal strains also correlate with the habitat conditions. We selected the rock-inhabiting crust lichen Protoparmeliopsis muralis, which exhibits high flexibility ...
Cheng Liang-Chien - - 2013
With the advancements in nanotechnology, studies on the synthesis, modification, application, and toxicology evaluation of nanomaterials are gaining increased attention. In particular, the applications of nanomaterials in biological systems are attracting considerable interest because of their unique, tunable, and versatile physicochemical properties. Artificially engineered nanomaterials can be well controlled for ...
Zhang Liangliang - - 2013
Based on the inhibition of double strand DNA (dsDNA) templated fluorescent copper nanoparticles (CuNPs) by pyrophosphate (PPi), a novel label-free turn-on fluorescent strategy to detect alkaline phosphatase (ALP) under physiological conditions has been developed. This method relies on the strong interaction between PPi and Cu2+, which would hamper the effective ...
Feng Shien-Ping - - 2013
A cost-effective and reliable Ni-Au contact on nanostructured Bi2Te3-based alloys for a solar thermoelectric generator (STEG) is reported. The use of MPS SAMs creates a strong covalent binding and more nucleation sites with even distribution for electroplating contact electrodes on nanostructured thermoelectric materials. A reliable high-performance flat-panel STEG can be ...
Hu Liang - - 2013
The paper reports robust ferromagnetic Cu-doped ZnO micron-scale polycrystalline films via spin-coating using high-quality doped nanocrystals. A reliable magnetic response is observed in the 900 °C vacuum annealed film without any ferromagnetic contribution from other sources. Post-annealing treatment in terms of atmosphere and temperature can control the proportion of oxygen ...
van der Pol Peggy - - 2013
AIMS: To compare the prevalence of mental disorders between frequent cannabis users with and without dependence and the general population. DESIGN: Cross-sectional comparison of interview data. SETTING: Enriched community sample of frequent cannabis users and a representative sample of non-users and non-frequent users from the general population. PARTICIPANTS: 521 young ...
Liu Feng - - 2013
In conventional photostimulable storage phosphors, the optical information written by x-ray or ultraviolet irradiation is usually read out as a visible photostimulated luminescence (PSL) signal under the stimulation of a low-energy light with appropriate wavelength. Unlike the transient PSL, here we report a new optical read-out form, photostimulated persistent luminescence ...
Carotenuto Marco - - 2013
Neurofibromatosis type 1 (NF1) is one of the most common autosomal dominant disorders with a prevalence of one in 4,000 people worldwide, associated with many neurological comorbidities, such as headache. Despite the high prevalence of headache in this population, little data exist regarding the classification of headaches experienced by patients ...
de Hoyos Adalberto - - 2013
INTRODUCTION: Cardiology is characterized by its state-of-the-art biomedical technology and the predominance of Evidence-Based Medicine. This predominance makes it difficult for healthcare professionals to deal with the ethical dilemmas that emerge in this subspecialty. This paper is a first endeavor to empirically investigate the axiological foundations of the healthcare professionals ...
Roullier C - - 2013
New Guinea is considered the most important secondary centre of diversity for sweet potato (Ipomoea batatas). We analysed nuclear and chloroplast genetic diversity of 417 New Guinea sweet potato landraces, representing agro-morphological diversity collected throughout the island, and compared this diversity with that in tropical America. The molecular data reveal ...
Cui Yimin - - 2013
Simple oxide heterostructures have been fabricated by depositing TbMnO3 thin films on Nb:SrTiO3 substrates at different temperatures. Remarkable switching with an on/off resistance ratio of ∼5000 is found in the sample grown at 720 °C, while only tiny resistive hysteresis can be observed in the sample grown at 650 °C. ...
Schmitt Christian - - 2013
In this systematic review, we aimed to compare conical versus non-conical implant-abutment connection systems in terms of their in vitro and in vivo performances. An electronic search was performed using PubMed, Embase, and Medline databases with the logical operators: "dental implant" AND "dental abutment" AND ("conical" OR "taper" OR "cone"). ...
Wright T J - - 2013
Early-stage cutaneous squamous cell carcinoma (cSCC) has a favourable prognosis. Metastatic disease is probably associated with chemoresistance mediated through the activation of pro-survival phosphatidylinositol 3-kinase/AKT signalling. Inhibition of activated AKT partially increases chemosensitivity but induces autophagy, the principal lysosomal mechanism for the bulk degradation and recycling of proteins and damaged ...
Wilson Aubrey M - - 2013
Development of an effective cytoplasmic delivery technique has remained an elusive goal for decades despite the success of pronuclear microinjection. Cytoplasmic injections are faster and easier than pronuclear injection and do not require the pronuclei to be visible; yet previous attempts to develop cytoplasmic injection have met with limited success. ...
Salimbene Ivano - - 2013
Since its original description in 1956 the association between interstitial lung disease and polymyositis (PM) and dermatomyositis (DM) has become well established. Interstitial lung disease (ILD) can be a significant complication in rheumatic diseases (RDs). Although most patients with RD do not develop clinically evident ILD, these systemic autoimmune disorders ...
Bonnì Sonia - - 2013
Recent studies showed that non-invasive brain stimulation methods, such as repetitive transcranial magnetic stimulation (rTMS) can improve the symptoms of neglect in stroke patients. Here, we adopted this approach to improve visuo-spatial deficit in a patient with traumatic brain injury (TBI) that showed important symptoms of visuo-spatial neglect. We found ...
Jesenska Sona - - 2013
Species sensitivity distribution (SSD) is commonly used in prospective risk assessment to derive predicted no-effect concentrations, toxicity exposure ratios, and environmental quality standards for individual chemicals such as pesticides. The application of SSD in the retrospective risk assessment of chemical mixtures at the river basin scale (i.e., the estimation of ...
Butler D P - - 2013
Background.  The rate of skin cancer in the UK continues to rise. Aim.  To identify the current knowledge and awareness of and attitudes towards the avoidance of skin cancer among a variety of patient groups to aid the design of future UK sun-awareness campaigns. Methods.  Patients aged ≥ 16 years presenting to ...
Negishi Yoichi - - 2013
Targeted gene delivery to neovascular vessels in tumors is considered a promising strategy for cancer therapy. We previously reported that "Bubble liposomes" (BL), which are ultrasound (US) imaging gas-encapsulating liposomes, were suitable for US imaging and gene delivery. When BLs are exposed to US, the bubble is destroyed, creating a ...
Wright Bernice - - 2013
The long-standing debate that polyphenol secondary metabolites from dietary plants are important nutritional components continues due to compelling evidence for their abilities to ameliorate degenerative conditions including, cancer, neurological disorders, and cardiovascular disease. The clinical use of polyphenols is not, however, main-stream as issues regarding poor selectivity, dosage, toxicity and ...
Zhou Jie - - 2013
BACKGROUND: Techniques that enable high levels of transgene expression in plants are attractive for the commercial production of plant-made recombinant pharmaceutical proteins or other gene transfer related strategies. The conventional way to increase the yield of desired transgenic products is to use strong promoters to control the expression of the ...
Sasagawa Tadashi - - 2013
Layered adipose-derived stem cell (ADSC) sheet transplantation is attracting attention as a new stem cell therapeutic strategy for damaged hearts. To prolong the function of thick tissue-engineered constructs after transplantation, a rapid and sufficient vascularization of engrafted tissue is essential. The in vitro formation of network structures derived from endothelial ...
Alizad Azra - - 2013
BACKGROUND: The purpose of this study was to evaluate the utility of a noninvasive ultrasound-based method, vibro-acoustography (VA), for thyroid imaging and determine the feasibility and challenges of VA in detecting nodules in thyroid. METHODS: Our study included two parts. First, in an in vitro study, experiments were conducted on ...
Bessho Marie - - 2013
The purpose of this study is to examine the molecular mechanism underlying the toxicity of arsenic trioxide (ATO) in cardiac cells. H9c2 rat cardiomyoblastoma cells undergo apoptosis during exposure to the concentrations of ATO > 10 μM for 24 h. The process is accompanied by the activation of caspases and is suppressed by ...
Chen Ying-Gang - - 2013
Currently, there is no universally accepted system to classify the stage IV colorectal cancer. Here, we analyze the prognostic impact of radical resection for colorectal liver metastases and propose a new staging system for stage IV colorectal cancer. A retrospective review was undertaken of 126 consecutive patients who underwent surgical ...
Fernández-Ros Nerea - - 2013
BACKGROUND: Post-treatment contralateral hemiliver hypertrophy has created an interest in lobar liver radioembolization (RE) as a pre-surgery tool. METHODS: Liver and spleen volumes and function were studied in 83 patients submitted to partial liver volume RE at 4-8 weeks (T1), 10-26 weeks (T2), and >26 weeks (T3) after RE. RESULTS: ...
Matthews Jonathan C F - - 2013
Quantum mechanics defines two classes of particles-bosons and fermions-whose exchange statistics fundamentally dictate quantum dynamics. Here we develop a scheme that uses entanglement to directly observe the correlated detection statistics of any number of fermions in any physical process. This approach relies on sending each of the entangled particles through ...
Luo Chunyan - - 2013
The proline-rich transmembrane protein 2 (PRRT2) gene has been recently identified as a causative gene of paroxysmal kinesigenic dyskinesia (PKD), with an insertion mutation c.649_650insC (p.P217fsX7) reported as the most common mutation. However, the pathogenic mechanism of the mutation of PRRT2 remains largely unknown. Resting-state functional magnetic resonance imaging is ...
Vermeirssen Etiënne L M - - 2013
The Chemcatcher passive sampler, which uses Empore™ disks as sampling phase, is frequently used to monitor polar organic chemicals in river water and effluents. Uptake kinetics need to be quantified to calculate time-weighted average concentrations from Chemcatcher field deployments. Information on release kinetics is needed if performance reference compounds (PRCs) ...
Oerlemans Anoek M - - 2013
Cognitive research proposes that social cognition (SC), executive functions (EF) and local processing style (weak CC) may be fruitful areas for research into the familial-genetic underpinnings of Autism Spectrum Disorders (ASD). The performance of 140 children with ASD, 172 siblings and 127 controls on tasks measuring SC (face recognition, affective ...
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