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Pucci Bruna - - 2013
The research of the last decade highlighted the existence of a family of genes activated by cellular stresses that allow the cells to reactivate defense and repair activities regardless of age. The prolonged activation of these genes enhances the organism health and lifespan. Members of this gene family are called ...
Nowak Przemysław - - 2013
The present study explored the antinociceptive effects of H3 (R-alpha-methylhistamine) and GABAB (baclofen) receptor ligands in an orofacial model of pain in rats. Orofacial pain was induced by subcutaneous injection of formalin (50 μl, 5 %) in the upper lip region, and the number of jumps and time spent face rubbing was ...
Sim Jaesam - - 2013
We propose a gas sensor operable over a wide temperature range and using suspended GaN nanowires functionalized with Pt-Pd. The sensor is batch-fabricated by directly integrating the GaN nanowires onto batch-processed silicon microelectrodes in parallel. The high thermal stability of the sensor originates from a large band gap of GaN ...
Reid David W - - 2013
Cystic fibrosis (CF) is the most common lethal genetic disorder in Caucasians, affecting more than 3,600 people in Australia and New Zealand, and more than 70,000 globally. Most of the morbidity and mortality relates to chronic airway infection commencing in early infancy and death usually occurs from respiratory failure (1, ...
Goldsmith S M - - 2013
The focus of Luttrell et al.'s recent publication that reports a clinical sensitivity of melanoma identification of 91.2%, and a sensitivity of diagnosis with added dermoscopy of 94.0%, is the enhanced sensitivity of melanoma identification with laypersons' use of dermoscopy.1 The new diagnostic approach that may have resulted in the ...
Barry Mitchel - - 2013
Whole breast irradiation (WBI) over 5-7 weeks has long been considered standard adjuvant treatment after breast-conserving surgery. Recently the concept of irradiating the whole breast has been challenged by accelerated partial breast irradiation (APBI), which exclusively targets the lumpectomy site plus margin. We review the evidence supporting APBI from modern clinical ...
Park Hosik - - 2013
Electrospinning and galvanic displacement reaction were combined to synthesize ultra-long hollow tellurium (Te) nanofibers with controlled dimensions, morphology and crystallinity by simply tailoring the electrolyte concentration applied. Within different morphologies of nanofibers, the branched Te nanostructure shows the greatest sensing performance towards NO2 at room temperature.
Guy Shlomit - - 2013
Integration of the HIV cDNA into the host chromosome is a key event in the viral replication cycle. It is mediated by the viral integrase (IN) enzyme, which is an attractive anti-HIV drug target. Here we present the first AFM imaging of IN-mediated DNA integration products in a two-LTR system.
Harms H - - 2013
OBJECTIVES: Stroke-associated pneumonia (SAP) is a common complication with a known negative impact on neurological outcome. We developed a score to identify patients at highest risk of SAP in order to promote prophylactic measures. MATERIALS AND METHODS: We conducted a cohort study on a neurological intensive care unit in patients ...
Nordén Marcus - - 2013
In the eggs and developing chick livers in the two wild bird species, great cormorant and herring gull, the concentrations of a range of 15 perfluoroalkyl acids (PFAAs) were determined. Eggs of the two species were collected from Lake Vänern, Sweden, and analysed either as undeveloped egg (whole egg or ...
Chen Jingfei - - 2013
To examine the self-assembly of cationic-anionic (catanionic) surfactant mixtures, we performed molecular dynamical (MD) simulations at fixed surfactant numbers but different ratios of cationic cetyltrimethylammonium bromide (CTAB) and anionic sodium octyl sulfate (SOS) aqueous mixtures, which were investigated previously (J. Phys. Chem. 1996, 100, 5874-5879). The simulation results show that ...
Gao Jun - - 2013
Lyophilic but not sticky! A lyophilic yet nonwettable surface seems self-contradictory, however, a nanostructured super-lyorepellent surface is used to reveal that a lyophilic nonwettable state is theoretically feasible in an oil/water/air/solid four-phase system. This finding may throw light on multiphase interface behavior.
Chiu Hsien-Jane - - 2013
BACKGROUND: The relationship between psychiatric disorders and musculoskeletal injuries is interesting but has not been investigated in depth. STUDY DESIGN: A retrospective cohort study, based on a large-sample nationwide database, was performed during 2000-2005 in Taiwan. METHODS: All subjects matching the inclusion criteria of psychiatric-associated ICD9-CM diagnostic codes in 2000 ...
Hossain Mohammad Zakir - - 2013
Dieting is very important to maintain a healthy and peaceful life. Today, most of the health problems are related with dieting. Thus, the modern health science recommends a number of suggestions regarding dieting for better health such as learning the five basic food groups (grains, vegetables, fruits, dairy, and meat); ...
Shi Gengbei - - 2013
Bioartificial liver devices (BALs) are extracorporeal systems designed to temporarily bridge patients until a suitable donated liver is available for transplantation and also have value for pharmaceutical testing applications. Yet critical issues exist that limit the functional performance of their current designs. One of these concerns scale up issues connected ...
Dong Yongping - - 2013
Electrogenerated chemiluminescence (ECL) behavior of a bismuth sulfide nanorods modified glassy carbon electrode (NR-GCE) was investigated in alkaline aqueous solution for the first time. One weak ECL peak of the NR-GCE was observed around -1.70 V when the electrode potential was scanned from 0.0 V to -2.0 V. The intensity ...
Bhangu Aneel - - 2013
BACKGROUND: All surgeons make mistakes, and learning from critical incidents may help improve performance. The present study aimed to highlight lessons for surgeons from analysis of the final moments of Air France Flight 447. All of the authors work in teams and situations where safety, technical performance, and non-technical skills ...
Abattouy N - - 2013
Anisakis infection parameters were studied in horse mackerel (Trachurus trachurus) taken from two areas of northern Morocco (Tetouan and Tangier), which showed a mean prevalence of 54.9%. Identification of the ITS1-5.8S-ITS2 fragment by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) showed A. pegreffii to be the dominant species; no A. ...
Voicescu Mariana - - 2013
The photophysical properties of luminol in a silver nanoparticles complex have been studied by steady-state and time resolved fluorescence spectroscopy. The effect of the serum albumin on the luminol fluorescence in the silver nanoparticles has been also investigated. It was found that the fluorescence quantum yield value of luminol in ...
Brandi Jessica - - 2013
The pancreatic adenocarcinoma cell line Panc1 was treated with cannabinoid receptor ligands (ACPA or GW405833) in order to elucidate the molecular mechanism of their anticancer effect. A proteomic approach was used to analyse the protein and phosphoprotein profiles. Western blot and functional data mining were also employed in order to ...
Allgaier Antje-Kathrin - - 2013
OBJECTIVE: The aim of the study was to compare criterion validities of the WHO-Five Well-being Index (WHO-5) and the Geriatric Depression Scale 15-item version (GDS-15) and 4-item version (GDS-4) as screening instruments for depression in nursing home residents. METHODS: Data from 92 residents aged 65-97 years without severe cognitive impairment (Mini ...
Dennison Laura - - 2013
This qualitative study was nested within a trial of cognitive behaviour therapy (CBT) and supportive listening for patients with multiple sclerosis (MS). It aimed to enrich understanding of the changes made during therapy and to explore processes of change. In-depth interviews with 30 participants from the treatment trial were analysed ...
Moro Federico L - - 2013
This manuscript proposes a method to directly transfer the features of horse walking, trotting, and galloping to a quadruped robot, with the aim of creating a much more natural (horse-like) locomotion profile. A principal component analysis on horse joint trajectories shows that walk, trot, and gallop can be described by ...
Loprinzi Paul D - - 2013
Objectives: Few population-based studies examining the association between tinnitus and depression among older adults have been conducted. Therefore, the purpose of this study was to examine the association between tinnitus and depression among a nationally representative sample of US older adults. Methods: Data from the 2005-2006 National Health and Nutrition ...
Worede G M - - 2013
The international Brown Swiss cattle population pedigree was studied to measure genetic variations and to identify the most influential animals. Twenty-two countries provided pedigree information on 71 497 Brown Swiss bulls used for artificial insemination (AI). The total number of animals with the pedigree is 181 094. The mean inbreeding ...
Cui Hong - - 2013
BACKGROUND: With the improvement of perinatal care and neonatal intensive care technology in recent years, a preterm infant, especially with small gestational age and very low birth weight, survives more and more. At the same time, adverse neurodevelopmental prognosis caused by brain damage in preterm infant also increased significantly. Preterm ...
Zhou Xiaosi - - 2013
Si-C hybrid nanofibers with a core-shell structure of Si nanoparticles confined in porous carbon nanofibers are fabricated by a single-nozzle electrospinning technique. The as-obtained Si nanoparticles/porous carbon hybrid nanofibers exhibit excellent properties in terms of cycling performance and rate capabilities for application as anode materials for lithium-ion batteries.
Liu Wei - - 2013
Simple and cheap alcohols can promote the direct arylation of unactivated arenes with aryl iodides and bromides in the presence of potassium tert-butoxide. This transition-metal-free aromatic C-H transformation offers a cheap and easy practical way to synthesize biaryls under mild conditions.
Ratnaningsih Enny - - 2013
Staphylococcus sp. WL1 lipase (LipFWS) was investigated for methanolysis of crude palm oil (CPO) at moderate temperatures. Experiments were conducted in the following order: searching for the suitable bacterium for producing lipase from activated sludge, sequencing lipase gene, identifying lipase activity, then synthesising CPO biodiesel using the enzyme. From bacterial ...
Horisawa Shiro - - 2013
BACKGROUND: Musician's dystonia is a task-specific movement disorder that causes twisting or repetitive abnormal finger postures and movements, which tend to occur only while playing musical instruments. Such a movement disorder will probably lead to termination of the careers of affected professional musicians. Most of the currently available treatments have ...
Neoh Chin Fen - - 2013
BACKGROUND: Micafungin demonstrated non-inferiority to caspofungin as definitive therapy for candidaemia and invasive candidiasis (IC) in a major randomised clinical trial. The aim of this study was to investigate if micafungin is a cost-saving option compared to caspofungin for treating candidaemia and IC. METHODS: A decision analytical model was constructed ...
Zhou Binbin - - 2013
An aniline-GGAAKLVFF peptide (AFP) was prepared by solid-phase synthesis. The peptide can readily self-assemble into fibrils. Platinum nanoparticles (Pt NPs) were directly immobilized on the surface of the AFP fibrils via electrostatic interaction. Compared to other currently available techniques for the fabrication of metal-peptide fibrils, the noncovalent functionalization strategy is ...
Yang Ming-Kun - - 2013
Increasing evidence shows that protein phosphorylation on serine (Ser), threonine (Thr) and tyrosine (Tyr) residues is one of the major post-translational modifications in the bacteria, involved in regulating a myriad of physiological processes. Cyanobacteria are one of the largest groups of bacteria, and are the only prokaryotes capable of oxygenic ...
Liu Zhirui - - 2013
Although various techniques have been employed to analyze drug metabolites, the metabolism of multi-component herbal medicine has seldom been fully addressed. In contrast to chemical drugs, a number of compounds in herbal medicine could get into circulation and then be metabolized. Metabolism study on active constituents in herbal medicine is ...
Lee Kwahun - - 2013
Glutaraldehyde causes especially high autofluorescence. It reacted with proteins and peptides to generate visible to near-IR emitters. A model indicated that ethylenediamine and a secondary amine in the molecule were key components for the formation of emissive species. The mechanism enables us to control the generation and elimination of autofluorescence.
Xie Hongyan - - 2013
Schistosome infection could cause significant liver damage in animal; Th2 cells play an important role in the progress of this disease. In our study, C57BL/6 mice were infected by Schistosoma japonicum and lymphocytes were isolated from the liver to detect some characteristics of interleukin-5 (IL-5)-producing T cells by different methods. ...
Gefroh Eva - - 2013
(1→3)-β-D-glucans (beta-glucans) have been found in raw materials used in the manufacture of recombinant therapeutics. Because of their biological activity, beta-glucans are considered process contaminants and consequently their level in the product needs to be controlled. While beta-glucans introduced into the cell culture process can readily be removed by bind-and-elute ...
Nandal Preeti - - 2013
Laccase production by Coriolopsis caperata RCK2011 under solid state fermentation was optimized following Taguchi design of experiment. An orthogonal array layout of L (2 × 3) was constructed using Qualitek-4 software with eight most influensive factors on laccase production. At individual level pH contributed higher influence, whereas, corn steep liquor ...
Badali Hamid - - 2013
Inter- and intraspecific genomic variability of 18 isolates of Veronaea botryosa originating from clinical and environmental sources was studied using amplified fragment length polymorphism (AFLP). The species was originally described from the environment, but several severe cases of disseminated infection in apparently healthy individuals have been reported worldwide. All tested ...
Guy Heather Miranda - - 2013
ProSavin® is a lentiviral vector (LV) based gene therapy for Parkinson's disease. ProSavin® is currently in a Phase I/II clinical trial using material that was generated by transient transfection of adherent human embryonic kidney (HEK)293T cells. For future large scale productions of ProSavin® we have previously reported the development and ...
Scharkoi Olga - - 2013
With the help of theoretical calculations we explain the phenomenon of nonplanarity of crystalline alternariol. We find out that the different orientations of the hydroxyl groups of alternariol influence its planarity and aromaticity and lead to different twists of the structure. The presence of the intramolecular hydrogen bond stabilizes the ...
Kirmani Deeba - - 2013
Abstract The oxidative role(s) of p66Shc protein has been increasingly expanded over the last decade. However, its relation with the most potent antioxidant molecule, i.e. ascorbic acid has never been studied. We have previously shown that p66Shc mediates rac1 activation, reactive oxygen species (ROS) production and cell death. Here we ...
Zhang Lei - - 2013
Previous studies showed that capsaicinoid supplementation favorably modifies the plasma lipoprotein profile. The present study investigated the effect of capsaicinoids on plasma lipids and gene expressions of key receptors and enzymes involved in cholesterol metabolism in ovariectomized (OVX) rats. OVX rats were fed with a cholesterol-free diet and orally administered ...
Furukawa Kentaro - - 2013
All living cells respond to external stimuli and execute specific physiological responses through signal transduction pathways. Understanding the mechanisms controlling signalling pathways is important for diagnosing and treating diseases and for reprogramming cells with desired functions. Although many of the signalling components in the budding yeast Saccharomyces cerevisiae have been ...
Al-Nammari Shafic Said - - 2013
The media are pivotal in educating and informing the general public. The stories they cover and how they cover them has a powerful influence on public perceptions. There have been no previous reports of the portrayal of bone tumours in the press. LexisNexis™ Professional search engine used to retrieve articles ...
Sie Karen K Y - - 2013
SCOPE: Intrauterine and early-life exposure to folic acid has significantly increased in North America owing to folic acid fortification, widespread supplemental use, and periconceptional supplementation. We investigated the effect of maternal and postweaning folic acid supplementation on DNA methylation in the rat offspring. METHODS AND RESULTS: Female rats were placed ...
Sgarbossa Antonella - - 2013
Intrinsic fluorescence of peptides and proteins is extensively used to monitor their specific interactions with several natural and synthetic molecules known to have wide-ranging beneficial or detrimental effects on health. A consequence of these interactions would be a significant decrease of the fluorescence emission intensity of Tyrosine (Tyr) and/or Tryptophan ...
Yang Hua - - 2013
Microemulsion electrokinetic chromatography (MEEKC) is a capillary electrophoresis (CE) separation technique which utilizes buffered microemulsions as the separation media. In the past two decades, MEEKC has blossomed into a powerful separation technique for the analysis of a wide range of compounds. Pseudostationary phase composition is so critical to successful resolution ...
Dai Jessica - - 2013
Purpose: The Medispec E3000TM is a new generation electrohydraulic lithotripter with a wider focal width comparable to the Dornier HM3TM. Herein, we evaluate the efficacy of this machine for treatment of urinary stones at our institution by shockwave lithotripsy (SWL). Materials and Methods: 168 urinary calculi were treated using the ...
Park Mi-Ryung - - 2013
Busulfan and cyclophosphamide (B/C)-treated mice exhibited a marked increase in apoptosis and a concomitant decrease in the ovarian weight. Histological and RT-PCR analysis indicate that the period of germ cell depletion in the B/C-treated ovaries coincides with decreased expression of genes Figla, Lhx8, Nobox, c-kit, and Sox3. However, depletion of ...
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