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Results 401 - 450 of 2685
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Dobbe J G G - - 2013
After a fracture of the distal radius, the bone segments may heal in a suboptimal position. This condition may lead to a reduced hand function, pain and finally osteoarthritis, sometimes requiring corrective surgery. Recent studies report computer-assisted 3-D planning techniques in which the mirrored contralateral unaffected radius serves as reference ...
de Bot Cindy Ma - - 2013
BACKGROUND: Polysensitisation is a frequent phenomenon in patients with allergic rhinitis. However, few studies have investigated the characteristics of polysensitised children, especially in primary care. OBJECTIVES: This analysis describes the patterns of sensitisation to common allergens and the association with age, gender, and clinical symptoms in children in primary care ...
Alvarez-Paggi Damián - - 2013
We have employed a combination of protein film voltammetry, time-resolved vibrational spectroelectrochemistry and molecular dynamics simulations to evaluate the electron transfer reorganization free energy (λ) of cytochrome c (Cyt) in electrostatic complexes that mimic some basic features of protein-protein interactions. The results reveal the existence of two native-like conformations of ...
Gelfer Polina - - 2013
BACKGROUND AND OBJECTIVES:The American Academy of Pediatrics stresses that NICUs should endorse and model the sudden infant deaths syndrome risk-reduction recommendations significantly before anticipated discharge of the infant. Medical personnel are critical role models for parents, and the way they position infants in the hospital strongly influences parental practices at ...
McKelvey Kim - - 2013
Scanning electrochemical cell microscopy (SECCM) is demonstrated as a new approach for the construction of extended multi-dimensional conducting polymer (polyaniline) nanostructures, making use of a mobile dual-channel theta pipette cell to control and monitor the location, rate and extent of electropolymerisation.
Sasaki Yasuyoshi - - 2013
[Co(bpy)3]3+/2+ and [Co(phen)3]3+/2+ redox couples were revealed to play as electron mediators for Z-scheme photocatalyst systems composed of Ru/SrTiO3:Rh and BiVO4 powders for overall water splitting under visible light irradiation. These electron mediators were effective for only the combination of SrTiO3:Rh with BiVO4. They did not work, when non-doped SrTiO3 ...
de Los Reyes Carolina - - 2013
A chemical study of the alga Cystoseira usneoides has led to the isolation of six new meroterpenoids, cystodiones A-F (1-6), together with six known related compounds (7-12). The structures of the new metabolites have been established by spectroscopic techniques. In antioxidant assays all of the tested meroterpenes, and in particular ...
Grensemann Joern - - 2013
BACKGROUND:Patients with lung failure who undergo prone positioning often receive extended hemodynamic monitoring. We investigated the influence of modified prone positioning (135°) on the accuracy of pulse contour-derived calibrated cardiac index (CIPC) and uncalibrated cardiac index (CIVIG) in this patient population with transpulmonary thermodilution (TPTD) as reference technique.METHODS:We studied 16 ...
Okamatsu Ayaka - - 2013
A large number of antitumor drug delivery carriers based on passive targeting and/or active targeting have been developed. However, encapsulation of antitumor drugs into these drug carriers is often complicated, and antitumor activities of these targeting systems are not satisfactory. In the present study, we first prepared heptakis-6-folic acid (FA)-appended ...
Sherman S Murray - - 2013
Metabotropic glutamate receptors (mGluRs) are found throughout thalamus and cortex and are clearly important to circuit behavior in both structures, and so considering only participation of ionotropic glutamate receptors (e.g., [R,S]-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid [AMPA] and N-methyl-d-aspartate receptors [NMDA] receptors) in glutamatergic processing would be an unfortunate oversimplification. These mGluRs are found ...
Rossi Andrés Hugo - - 2013
Polymorphisms occurring at the p6<sub><i>gag</i></sub> protein of HIV-1 have been previously found to have an impact on viral fitness and ARV resistance, mainly on subtype B genomes. We compared p6<sub><i>gag</i></sub> variability in large group of 165 subtype F <i>gag-pol</i> sequences, with 36 subtype B sequences from the same study source, ...
Crispi Stefania - - 2013
Endometriosis is a common benign pathology, characterised by the presence of endometrial tissue outside the endometrial cavity with a prevalence of 10-15% in reproductive-aged women. The pathogenesis is not completely understood, and several theories have been proposed to explain the etiology. Our group has recently described the presence of ectopic ...
Gennari-Moser Carine C Department of Nephrology, Hypertension and Clinical Pharmacology, University Hospital Bern, Berne, - - 2013
Aldosterone levels are markedly elevated during normal pregnancy but fall even though volume contracts when preeclampsia occurs. The level of aldosterone in either condition cannot be explained solely by the activity of the renin-angiotensin II system. In normal gestation, vascular endothelial growth factor (VEGF) is thought to maintain vascular health, ...
Iwai Tomohiro - - 2013
Semihollow triethynylphosphanes were synthesized and employed as ligands in the gold-catalyzed 8-exo-dig cyclization of acetylene-tethered silyl enol ethers to obtain eight-membered-ring carbocycles. The gold-phosphane catalysts promoted either the annulation toward bicyclic structures or the cyclization of acyclic molecules to form nonfused carbocycles.
Klein Susanne - - 2013
In recent years, several papers reported an enhanced dielectric anisotropy when ferroelectric particles were suspended in a liquid crystal. These results seem to be sensitive to the liquid crystal used and the preparation method of the ferroelectric particles. In this paper, we compare different preparation methods of suspended barium titanate ...
Hennenberg Martin - - 2013
BACKGROUND: Binding of clathrins or caveolin to G protein-coupled receptors may induce post-translational modifications of receptor function. Receptor regulation by clathrin requires cofactors ADP-ribosylation factor 6 (ARF6) and adaptin, while dynamin is required for clathrin- and caveolin-dependent mechanisms. OBJECTIVE: To investigate the expression and α1-adrenoceptor binding of clathrins, caveolin, and ...
Sangwan Manuvesh - - 2013
Reaction of methyl radicals with hydroperoxy radicals, CH3 + HO2  products (1) was studied using pulsed laser photolysis coupled to transient UV-Vis absorption spectroscopy at 295 K and 1 bar (He). Photolysis of N2O/H2O2/CH4/H2O/He mixtures at 193.3 nm (ArF excimer laser) was used to simultaneously produce methyl radicals and ...
Plumb Ellen - - 2013
Global health education and health promotion have the potential to engage students, scholars, and practitioners in ways that go beyond the classroom teaching routine. This engagement in global communities, can range from reflection on continuing deep-seated questions about human rights and civic responsibility to the use of health education and ...
Musumeci Matias A MA Alberta Glycomics Centre, Department of Biological Sciences, University of Alberta, Edmonton, Alberta T6G 2E9, - - 2013
Oligosaccharyltransferases (OTases) are enzymes that catalyze the transfer of an oligosaccharide from a lipid carrier to an acceptor molecule, commonly a protein. OTases are classified as N-OTases and O-OTases, depending on the nature of the glycosylation reaction. The N-OTases catalyze the glycan transfer to amide groups in asparagines in a ...
Wang Weiyang - - 2013
Bimetallic highly branched Pt-Ni nanocrystals were obtained by a one-pot strategy. The dendritic alloyed structure of the as-prepared nanoparticles was fully characterized and their formation mechanism was investigated. Nitrobenzene hydrogenation reactions indicated that these obtained Pt-Ni nanodendrites exhibited enhanced catalytic activities compared with Pt-Ni nanoparticles.
Pelkonen Tuula - - 2013
The human herpesviruses (HHVs), DNA viruses that include herpes simplex virus (HSV) 1 and 2, varicella zoster virus (VZV), Epstein-Barr virus (EBV), cytomegalovirus (CMV), and human herpesvirus (HHV) 6A, 6B, and 7, and Kaposi's sarcoma-associated herpesvirus (KSHV), can cause encephalitis or meningitis in children, and result in residual neurologic sequelae ...
Ceruti Julieta M - - 2013
ING proteins are tumor suppressors involved in the regulation of gene transcription, cell cycle arrest, apoptosis, and senescence. Here, we show that ING1b expression is upregulated by several DNA-damaging agents, in a p53-independent manner. ING1b stimulates DNA repair of a variety of DNA lesions requiring activation of multiple DNA repair ...
Kim Mean-Hwan MH Oregon Health Sciences University, Vollum Institute L-474, 3181 SW Sam Jackson Park Rd, Portland, OR 97239-3098, - - 2013
Hair cell synapses in the ear and photoreceptor synapses in the eye are the first synapses in the auditory and visual system. These specialized synapses transmit a large amount of sensory information in a fast and efficient manner. Moreover, both small and large signals with widely variable kinetics must be ...
Ferrar Kyle John - - 2013
Unconventional natural gas development in Pennsylania has created a new wastewater stream. On May 19, 2011 the Pennsylvania Department of Environmental Protection, in an effort to stop the discharge of Marcellus Shale unconventional gas development wastewaters to surface waters, requested drilling companies stop disposing their wastewater through facilities that discharge ...
Gutiérrez-Redomero Esperanza - - 2013
Variability in ridge density in a sub-Saharan population sample was studied by counting ridges in three fingerprint areas (two distal regions, radial and ulnar, and one proximal region) on the epidermal surface of the distal phalanx. Study material was obtained from the fingerprint impressions of 100 male sub-Saharan subjects aged ...
Jaeger Heather M - - 2013
Third-generation photovolatics require demanding cost and power conversion efficiency standards, which may be achieved through efficient exciton multiplication. Therefore, generating more than one electron-hole pair from the absorption of a single photon has vast ramifications on solar power conversion technology. Unlike their bulk counterparts, irradiated semiconductor quantum dots exhibit efficient ...
Ventura Francesco - - 2013
The finding of a mummified body raises many problems, also because of the limits of the medico-legal investigations in case of mummification. Psychological autopsy and behavioral analysis have demonstrated a significant impact in case of equivocal death. The mummified corpse of a woman was found sealed in a wardrobe during ...
Mosele Marco - - 2013
PURPOSE: The association between serum 25-hydroxyvitamin D values and cortical/trabecular bone parameters in older adults has been incompletely explored. This study was designed to investigate the relationship between serum 25-hydroxyvitamin D levels and bone parameters for the tibia and radius using peripheral quantitative computed tomography in free-living healthy older adults. ...
Sun Victor Z - - 2013
An arginine-leucine block copolypeptide (R60 L20 ) is synthesized, which is capable of forming vesicles with controllable sizes, able to transport hydrophilic cargo across the cell membrane, and exhibit relatively low cytotoxicity. The R60 L20 vesicles also possess the ability to deliver DNA into mammalian cells for transfection. Although the ...
Fenstermacher Kimberly K Department of Nursing, York College of Pennsylvania, York, PA, - - 2013
To report an analysis of the concept of perinatal bereavement. The concept of perinatal bereavement emerged in the scientific literature during the 1970s. Perinatal bereavement is a practice-based concept, although it is not well-defined in the scientific literature and is often intermingled with the concepts of mourning and grief. Concept ...
Sanders Jennifer L - - 2013
Optical tweezers are exciting tools with which to explore liquid crystal (LC) systems; the motion of particles held in laser traps through LCs is perhaps the only approach that allows a low Ericksen number regime to be accessed. This offers a new method of studying the microrheology associated with micrometre-sized ...
Marsigliante Santo - - 2013
The communication between the tumour cells and the surrounding cells helps drive the process of tumour progression. Since the microenvironment of breast cancer includes CCL20 chemokine, the purpose of this study was to determine whether CCL20 modulates the physiology of healthy breast epithelial cells in areas adjacent to the tumour. ...
Vogel David L - - 2013
Researchers have found that the stigma associated with seeking therapy-particularly self-stigma-can inhibit the use of psychological services. Yet, most of the research on self-stigma has been conducted in the United States. This is a considerable limitation, as the role of self-stigma in the help-seeking process may vary across cultural groups. ...
Aerts Isabelle - - 2013
PURPOSEThe objective of this prospective study was to assess overall survival and event-free survival in patients with intraocular unilateral retinoblastoma (Reese-Ellsworth group V) treated by primary enucleation with or without adjuvant therapy depending on histopathologic risk factors. PATIENTS AND METHODSPatients (n = 123) were divided into three groups on the ...
Campbell Karen J - - 2013
OBJECTIVE:To assess the effectiveness of a parent-focused intervention on infants' obesity-risk behaviors and BMI.METHODS:This cluster randomized controlled trial recruited 542 parents and their infants (mean age 3.8 months at baseline) from 62 first-time parent groups. Parents were offered six 2-hour dietitian-delivered sessions over 15 months focusing on parental knowledge, skills, ...
Nunn Samuel - - 2013
A project by a metropolitan police agency in 2008-2009 had police use touch DNA kits to collect cell samples from seized firearms. To assess outcomes, results of touch DNA swabbing of firearms were compared to fingerprinting firearm evidence. The rationale was that fingerprinting, as the older technology, was the baseline ...
Hawker Gillian A - - 2013
OBJECTIVE: To evaluate patient predictors of 'good outcome' following total joint arthroplasty (TJA). METHODS: A population cohort with hip/knee arthritis (osteoarthritis, OA; inflammatory arthritis, IA) aged 55+ years was recruited (1996-98; baseline) and assessed annually (demographics, troublesome joints, health status and overall hip/knee arthritis severity [WOMAC]). Survey data were linked ...
Bruins Benjamin B Department of Pediatrics, Washington University in St. Louis School of Medicine, Campus Box 8028, 5th Floor MPRB, 660 S. Euclid Ave., St. Louis, MO 63110. - - 2013
The effect of various sedatives and anesthetics on vasopressor modulation of cerebral blood flow (CBF) in children is unclear. In adults, isoflurane has been described to decrease CBF to a lesser extent than fentanyl and midazolam. Most large-animal models of neurocritical care use inhaled anesthetics for anesthesia. Investigations involving modulations ...
Frank Kristi L - - 2013
Enterococcus faecalis is part of the human intestinal microbiome and is a prominent cause of health care-associated infections. The pathogenesis of many E. faecalis infections, including endocarditis and catheter-associated urinary tract infection (CAUTI), is related to the ability of clinical isolates to form biofilms. To identify chromosomal genetic determinants responsible ...
Viviano K R - - 2013
BACKGROUND: Antioxidant depletion and lipid peroxidation have been correlated with disease severity and associated with poor outcomes. HYPOTHESIS/OBJECTIVES: Supplementing dogs with N-acetylcysteine (NAC) during the first 48 hours of hospitalization will increase cysteine, normalize glutathione concentrations, and decrease the degree of lipid peroxidation associated with illness. ANIMALS: Sixty systemically ill hospitalized ...
Pan Shu-Yuan - - 2013
Both basic oxygen furnace (BOF) slag and cold-rolling wastewater (CRW) exhibiting highly alkaline characteristics require stabilization and neutralization prior to utilization and/or final disposal. Using CO2 from flue gases as the stabilizing and neutralizing agents could also diminish CO2 emissions. In this investigation, ex-situ hot stove gas containing 30 vol% ...
Brilhante Raimunda Sâmia Nogueira - - 2013
Coccidioidomycosis is a systemic mycosis caused by the dimorphic fungi Coccidioides spp. The treatment for chronic and/or disseminated coccidioidomycosis can be prolonged and complicated. Therefore, the search for new drugs is necessary. Farnesol is a precursor in the sterol biosynthesis pathway that has been shown to present antifungal activity. Thus, ...
Bonfiglio Andrea - - 2013
Intravitreal drug delivery is a commonly used treatment for several retinal diseases. The objective of this research is to characterize and quantify the role of the vitreous humor motion, induced by saccadic movements, on drug transport processes in the vitreous chamber. A Perspex model of the human vitreous chamber was ...
Teehan Paul - - 2013
Information and communications technology (ICT) contributes substantially to global greenhouse gas (GHG) pollutant emissions, but it is time consuming to estimate the environmental impacts caused by the production of ICT devices, and the literature lacks coverage for newer products. Using a process-sum life cycle assessment (LCA) approach, we estimate and ...
Wander Katherine K Department of Anthropology, University of Washington, Seattle, WA 98195, USA. - - 2013
We evaluated sex, age, nutritional status, and infectious disease (ID) as predictors of two biomarkers of cell-mediated immunity (CMI), delayed-type hypersensitivity to Candida albicans (DTH-Candida), and anti-Epstein-Barr virus antibody (EBV Ab), among 200 children in Kilimanjaro, Tanzania. DTH-Candida, which decreases with compromised CMI, was positively associated with age (OR: 1.27; ...
Grossman Sara - - 2013
Health care practitioners have increasingly used the Internet to obtain health and medication information. The vast number of Internet Web sites providing such information and concerns with their reliability makes it essential for users to carefully select and evaluate Web sites prior to use. To this end, this article reviews ...
Tourville Timothy W - - 2013
BACKGROUND:Progression of primary knee osteoarthritis (OA) is often quantified by measuring structural alterations of the joint such as those in tibiofemoral joint space width (JSW) over time. Limited information is available regarding changes that occur during the onset and progression of posttraumatic OA (PTOA) that are often associated with anterior ...
Turco Eleonora - - 2013
The MUTYH DNA-glycosylase is indirectly engaged in the repair of the miscoding 7,8-dihydro-8-oxo-2'-deoxyguanine (8-oxodG) lesion by removing adenine erroneously incorporated opposite the oxidized purine. Inherited biallelic mutations in the MUTYH gene are responsible for a recessive syndrome, the MUTYH-associated polyposis (MAP), which confers an increased risk of colorectal cancer. In ...
Greasty Robert J - - 2013
The response of anisotropic pigment particle suspensions to externally applied electric fields has been explored for possible application in reflective display technologies. Three different types of pigment particle were suspended in dodecane, using a polymeric stabilizer, and showed Schlieren textures between crossed polarizers at high concentrations (greater than 25-30 wt%), indicating ...
Li Ling - - 2013
Zipper examined: High-quality boron nitride nanoribbons (BNNRs) can be produced directly during nanotube synthesis without post-treatment. These BNNRs are typically several micrometers long and tens of nanometers wide. Near-edge X-ray absorption fine structure investigations indicated that the BNNRs are of high chemical purity and crystallinity.
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