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Rudy Yoram Y Cardiac Bioelectricity and Arrhythmia Center, Washington University, One Brookings Dr, St Louis, MO 63130-4899, USA. - - 2013
Cardiac excitation is determined by interactions between the source of electric activation (membrane depolarization) and the load that cardiac tissue presents. This relationship is altered in pathology by remodeling processes that often create a substrate favoring the development of cardiac arrhythmias. Most studies of arrhythmia mechanisms and arrhythmogenic substrates have ...
Chen Ying-Lien - - 2013
The pathogenic yeast , which is causing an outbreak in the Pacific Northwest region of North America, causes life-threatening pulmonary infections and meningoencephalitis in healthy individuals, unlike , which commonly infects immunocompromised patients. In addition to a greater predilection for to infect healthy hosts, the genome sequence project revealed extensive ...
Chao Hui-Lin - - 2013
To evaluate the effectiveness of ST-36 (Zusanli) acupressure on recovery of postoperative gastrointestinal function in patients with colorectal cancer. A longitudinal, randomized, controlled trial design. An urban medical center in Taiwan. 60 patients with colorectal cancer who had undergone abdominal surgery. Patients were randomly assigned to two groups, the ST-36 ...
Machida Mayumi - - 2013
Controllable stress, modeled by escapable shock (ES), can produce significant alterations in post-stress sleep, including increased rapid eye movement (REM) sleep. Recent work has demonstrated that post-stress sleep may be influenced by stressor predictability, modeled by predictive auditory cues. In this study, we trained mice with ES, either signaled (SES) ...
Robinson Susan J SJ Centers for Disease Control and Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Atlanta, GA 30333, USA. - - 2013
Recognizing the need to work with all partners who have an interest in addressing sexual health issues, we explored values held by diverse stakeholders in the United States. Based on these findings, we developed a framework for use in communicating about sexual health issues and potential solutions. Our methods included ...
Xu Yanqing - - 2013
The self-assembly procedure of a Dawson-type polyoxotungstate with pyridine-2,6-dicarboxylate (H2pdc) and copperII ions produces an exquisite supramolecular aggregation. In the structure, a neutral cucurbit[n]uril-like metal-organic macrocycle is formed of six copper centers and six pdc2- ligands, while a pair of Dawson-type polyoxotungstates are linked to the bottom and top portals ...
van Oterendorp Christian - - 2013
Retinal ganglion cells (RGC) are a relatively small cell population in the retina. This leads to an unfavorable signal-to-noise ratio when analyzing RGC proteins in whole retina lysate. We present a novel technique to obtain RGC-enriched rat retinal lysate by removing the outer retinal layers with an excimer laser before ...
Bondici V F - - 2013
AIMS: To describe the diversity and metabolic potential of microbial communities in uranium mine tailings characterized by high pH, high metal concentration and low permeability. METHODS AND RESULTS: To assess microbial diversity and their potential to influence the geochemistry of uranium mine tailings using aerobic and anaerobic culture-based methods, in ...
Zhang Lei - - 2013
A simple and efficient Ru-catalyzed conjugate addition reaction of arylboronic acids to alpha,beta-unsaturated ketones under neutral conditions without any additional ligands has been developed. This Ru(II)-catalytic system fulfilled both the inhibition of the beta-hydride elimination in the catalytic cycle, and minimized the protonolysis of arylboronic acids.
Tingen Martha S MS Child Health Discovery Institute, Georgia Prevention Institute, Medical College of Georgia, Georgia Health Sciences University, Augusta, GA 30912, USA. - - 2013
This study evaluated similarities and differences of enrollment rates using two different recruitment strategies for a tobacco control trial in rural and urban African-American (AA) elementary school families. A comparative study, nested within a larger randomized controlled trial, was used to test the effectiveness of two recruitment approaches on enrollment ...
Ranney Richard R - - 2013
Dr. Ranney provides a commentary about two 1924 articles published in The Journal of the American Dental Association by Dr. William John Gies that highlight his many contributions to dental education.
Verble Margaret - - 2013
Context-The request process for eye and tissue donation is different from the process that families of organ donors experience, but the research into eye/tissue-only decision making has been sparse.Objective-To determine the concerns of families approached over the phone for eye/tissue donations and to study the impact of the donor registry ...
Wallingford John B - - 2013
Human birth defects are a major public health burden: The Center for Disease Control estimates that 1 of every 33 United States newborns presents with a birth defect, and worldwide the estimate approaches 6% of all births. Among the most common and debilitating of human birth defects are those affecting ...
Qiu Penghe P Department of Chemistry and Biochemistry, Stephenson Life Sciences Research Center, University of Oklahoma, Norman, OK 73019, - - 2013
A novel scaffold composed of loosely branched hollow silica microfibers that has been proven to be highly biocompatible is proposed for the 3D culture of cancer cells. The MCF-7 cancer cells can grow and proliferate freely inside the scaffold in the form of multicellular spheroids. MCF-7 cancer cells cultured on ...
Dai Zhi - - 2013
The chromatographic chiral resolution of 4-aryl-1,4-dihydropyridines (1-32), 4-aryl-2-thioxo-1,2,3,4-tetrahydropyrimidines (33-38), and 4-aryl-2-oxo-1,2,3,4-tetrahydropyrimidines (39-41) was studied on a tetraproline-immobilized chiral column synthesized in our lab. This tetraproline chiral stationary phase can resolve most of these compounds. The 4-aryl-2-thioxo-1,2,3,4-tetrahydropyrimidines (33-38) and 4-aryl-2-oxo-1,2,3,4-tetrahydropyrimidines (39-41) were more efficiently resolved than the racemic 4-aryl-1,4-dihydropyridines on the ...
Wang Miao - - 2013
Mechanically excellent native cellulose nanofibers that are cleaved from plant cell walls have been modified by functionalized few-walled carbon nanotubes for hybrid nanofiber/nanotube aerogels. They show elastic mechanical behavior in combination with reversible electrical response under compression allowing responsive conductivity and pressure sensing. The concept combines wide availability of nanocellulosics ...
Janjua Halima S - - 2013
Objective-As kidney transplant is the preferred mode of management of advanced kidney disease and economic trends for kidney transplant procedures are not well known, data were analyzed to assess these trends.Data Source-Annual data for 1998 to 2008 from the Nationwide Inpatient Sample, Healthcare Cost and Utilization Project, Agency for Healthcare ...
Karatas Hulya - - 2013
The initial phase in the development of a migraine is still poorly understood. Here, we describe a previously unknown signaling pathway between stressed neurons and trigeminal afferents during cortical spreading depression (CSD), the putative cause of migraine aura and headache. CSD caused neuronal Pannexin1 (Panx1) megachannel opening and caspase-1 activation ...
Song Sukhyun - - 2013
Cells are inherently exposed to a number of different biophysical stimuli such as electric fields, shear stress, and tensile or compressive stress from the extracellular environment in vivo. Each of these biophysical cues can work simultaneously or independently to regulate cellular functions and tissue integrity in both physiological and pathological ...
Vyhlidal Carrie A - - 2013
BACKGROUND: Differences in mRNA expression for inflammatory markers have been observed between subjects with asthma vs. controls and in relation to corticosteroid response. However, these studies utilized methods (e.g., bronchoscopy) that are too invasive to be used routinely in children and in the clinic. The primary purpose of this study ...
Nishimura Hiroaki - - 2013
Peripheral arterial disease (PAD) is very common in dialysis patients, who tend to have diffuse calcification and severe peripheral arterial stenosis that make it difficult to treat limbs using only surgical or endovascular interventions. Better ways to treat this condition are therefore required and also follow-up studies to evaluate the ...
Metcalfe A J - - 2013
The aim of this study was to examine the loading of the other joints of the lower limb in patients with unilateral osteoarthritis (OA) of the knee. We recruited 20 patients with no other symptoms or deformity in the lower limbs from a consecutive cohort of patients awaiting knee replacement. ...
Bandi Venugopal - - 2013
A novel broad-band capturing and emitting supramolecular triad useful for solar energy harvesting and building optoelectronic devices is reported.
Sim Dawn A - - 2013
To investigate the impact of diabetic macular ischemia (DMI) on visual acuity (VA), through the analysis of novel fluorescein angiography (FA) parameters. Data were retrospectively collected over a 6-month period. DMI severity was graded using Early Treatment Diabetic Retinopathy Study (ETDRS) protocols. Custom software was used to quantify areas of ...
Liu Xiaoran - - 2013
Background: Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in patients with moderate-to-severe chronic obstructive pulmonary disease (COPD), with > 44% of these patients presenting with generalized atherosclerosis at autopsy. It is accepted that endothelial progenitor cells (EPCs) participate in the repair of dysfunctional endothelium, thereby, protecting ...
Tojo Shinjiro - - 2013
STUDY DESIGN.: A retrospective, consecutive case series. OBJECTIVE.: To analyze the relationship between retro-odontoid soft-tissue thickness and patients' age, sex, and degenerative changes of cervical spine and to investigate the effect these factors have on retro-odontoid soft-tissue thickness. SUMMARY OF BACKGROUND DATA.: Thickening of the soft tissue posterior to the ...
Hannedouche Jérôme - - 2013
Asymmetric hydroamination allows the direct and selective formation of a new CN bond as a simple procedure towards valuable scalemic synthons. Huge efforts have recently been made to overcome the challenges associated with this transformation. This non-comprehensive Concept article aims at pointing out the most recent and original progresses, offering ...
Schönwald Liane I - - 2013
In our previous studies on competition for attentional processing resources in early visual cortex between a foreground task and distracting emotional background images we found that emotional background images withdraw attentional resources from the foreground task after about 400 ms. Costs in behavioral data and a significant reduction of the ...
Lu M-Y - - 2013
BACKGROUND: The aims of our study were to evaluate (i) the relationship between cardiac T2* values and cardiac complications in Asian β-thalassaemia major (TM) patients, and (ii) the association between cardiac T2* values and other parameters currently used to predict cardiac complications as a result of transfusion iron overload. METHODS: ...
Petrović Andjeljko - - 2013
We report the occurrence of Lysiphlebus orientalis in Serbia, an aphid parasitoid from the Far East that is new to Europe and has the potential to become invasive. Our finding based on morphological characters is confirmed by analyses of mitochondrial cytochrome oxidase subunit I sequences. An increase in number and ...
Beryozkin Avigail - - 2013
We evaluated the role of Crumbs homolog 1 (CRB1) in autosomal recessive (AR) retinal diseases in the Israeli and Palestinian populations using homozygosity mapping. Clinical analysis included family history, ocular examination, full-field electroretinography (ERG), and funduscopy. Molecular analysis included homozygosity mapping using whole genome single nucleotide polymorphism (SNP) arrays and ...
Carlsson Annelie - - 2013
This 26-wk observational study in children and adolescents with type 1 diabetes (T1D) in Sweden investigated the safety and efficacy of insulin detemir (IDet) in newly diagnosed (ND) patients and those with established diabetes (ED) switching to IDet. A total of 159 patients initiated IDet as part of basal-bolus therapy, ...
Martín-Peláez Sandra - - 2013
The Mediterranean diet and consumption of olive oil have been connected in several studies with longevity and a reduced risk of morbidity and mortality. Lifestyle, such as regular physical activity, a healthy diet, and the existing social cohesion in Southern European countries have been recognised as candidate protective factors that ...
Inami Yoshihiro - - 2013
Effects of chlorogenic acid on surfactant-induced itching were studied in mice. Topical application of sodium laurate increased hind-paw scratching, an itch-related response, 2 h after application, which was inhibited by topical post-treatment with chlorogenic acid. Sodium laurate increased the histamine content and 53-kDa l-histidine decarboxylase in the epidermis, which were ...
Gauster Martin - - 2013
Besides microfilaments and microtubules, intermediate filaments are major components of the cytoskeleton. In epithelial cells intermediate filaments are formed by heterodimers of specific keratins, whose expression pattern highly depends on the type of epithelium and differentiation degree of the cell. During the process of blastocyst implantation and subsequent development of ...
Ribbans W J - - 2013
The incidence of acute and chronic conditions of the tendo Achillis appear to be increasing. Causation is multifactorial but the role of inherited genetic elements and the influence of environmental factors altering gene expression are increasingly being recognised. Certain individuals' tendons carry specific variations of genetic sequence that may make ...
McMillin Douglas W - - 2013
The role of stromal cells and the tumour microenvironment in general in modulating tumour sensitivity is increasingly becoming a key consideration for the development of active anticancer therapeutics. Here, we discuss how these tumour-stromal interactions affect tumour cell signalling, survival, proliferation and drug sensitivity. Particular emphasis is placed on the ...
Grathwohl Stefan A - - 2013
Read the full article 'Activity-dependent secretion of alpha-synuclein by enteric neurons' on doi: 10.1111/jnc.12131.
Gharbiya M M Department of Ophthalmology, Sapienza University, Umberto I Hospital, Rome, Italy. - - 2013
To determine macular thickness changes after uncomplicated cataract surgery using spectral domain optical coherence tomography (OCT). This was a prospective non-randomized, clinical study. Data were analysed for 40 healthy patients undergoing uneventful phacoemulsification. OCT measurements were performed before surgery and postoperatively at day 1, week 1 and 2, and month ...
Horacek Tanya M - - 2013
Abstract Purpose. This study evaluated the food stores on and near postsecondary campuses varying in institutional size. Design. The design of the study is an environmental audit survey. Setting. Fifteen U.S. postsecondary education institutions participated in this study between 2009-2011. Subjects. Eighty-one stores (44% grocery, 17% campus, and 39% convenience/drug) ...
Torres-Quinones Maritza - - 2013
Context-Aging, higher prevalence of diabetes, worsening obesity, and hyperglycemia among potential donors increase the likelihood that pancreata will be declined by transplant centers. Hemoglobin A1c testing, also known as glycated hemoglobin testing, identifies a donor's average blood glucose concentration for the preceding 2 to 3 months and is the standard ...
Giovanoli Sandra S Physiology and Behavior Laboratory, Swiss Federal Institute of Technology (ETH) Zurich, 8603 Schwerzenbach, - - 2013
Prenatal infection and exposure to traumatizing experiences during peripuberty have each been associated with increased risk for neuropsychiatric disorders. Evidence is lacking for the cumulative impact of such prenatal and postnatal environmental challenges on brain functions and vulnerability to psychiatric disease. Here, we show in a translational mouse model that ...
Ta Michelle H T - - 2013
Interstitial infiltrates, consisting of macrophages and other inflammatory cells, have been consistently reported in human and animal models of polycystic kidney diseases (PKD). However, the mechanisms underlying this inflammation are not well defined. Evidence suggests that interstitial inflammation in PKD is driven by pro-inflammatory chemoattractants such as monocyte chemoattractant protein-1 ...
Nystrom Robert J RJ Oregon Public Health Division, Adolescent, Genetic and Reproductive Health Section, Portland, OR 97232, USA. - - 2013
Oregon's work on teen pregnancy prevention during the previous 20 years has shifted from a risk-focused paradigm to a youth development model that places young people at the center of their sexual health and well-being. During 2005, the Oregon Governor's Office requested that an ad hoc committee of state agency ...
Fulker David - - 2013
The vascular access used in hemodialysis can suffer from numerous complications, which may lead to failure of the access, patient morbidity, and significant costs. The flow field in the region of the venous needle may be a source of damaging hemodynamics and hence adverse effects on the fistula. In this ...
Rancière Fanny - - 2013
BACKGROUND: Early detection of children at risk for developing allergy is an important challenge. Our first analyses in infants from the Pollution and Asthma Risk: an Infant Study (PARIS) birth cohort suggested that dry night cough was associated with parental-reported allergic disorders. The aim of the present study was to ...
Verstraete Esther - - 2013
Amyotrophic lateral sclerosis (ALS) is a severe neurodegenerative disease, which primarily targets the motor system. The structural integrity of the motor network and the way it is embedded in the overall brain network is essential for motor functioning. We studied the longitudinal effects of ALS on the brain network using ...
Ganaiem Hammam - - 2013
BACKGROUND: Veno-occlusive disease with immunodeficiency (VODI) is an autosomal recessive disorder of combined immunodeficiency (CID) and hepatic injury. Hematopoietic stem cell transplantation (HSCT) - the only definitive treatment for CID - appeared to have a high rate of complications in a previous report. In this study, we describe a new ...
Mari Jean Martial - - 2013
We improved the visibility of the lamina cribrosa (LC), including its posterior boundary, in optical coherence tomography (OCT) images of the human optic nerve head (ONH). An adaptive compensation algorithm was developed to overcome a limitation of our standard compensation algorithm, that is the overamplification of noise at high depth. ...
Wei Zhen - - 2013
The site-specific labeling of proteins with paramagnetic lanthanides offers unique opportunities for NMR spectroscopic analysis in structural biology. Herein, we report an interesting way of obtaining paramagnetic structural restraints by employing noncovalent interaction between a lanthanide metal complex, [Ln(L)3 ]n- (L=derivative of dipicolinic acid, DPA), and a protein. These complexes ...
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