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Results 201 - 250 of 2925
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Torigoe Tsukasa - - 2013
This is the first report of a coronary artery with an anomalous origin from the proper sinus resulting in ischemic events in a child. Transthoracic echocardiogram, computed tomogram, and coronary angiogram revealed that, although the left main coronary trunk originated from the left sinus, its ostium was displaced horizontally and ...
MacDonald Michael R Bob MR Navy and Marine Corps Public Health Center, Sexual Health and Responsibility Program, Portsmouth, VA 23708, USA. - - 2013
In 1999, the Navy and Marine Corps Public Health Center converted an HIV train-the-trainer program into a broader effort of preventing not just HIV, but also other sexually transmitted infections (STIs) and unplanned pregnancies. The premise for this broader approach was that a more comprehensive sexual health promotion message of ...
Roy Lise - - 2013
Pesticide applications have a strong impact on biodiversity in agroecosystems. The present study aimed to assess the impact of pest control strategies on the arthropodofauna of Parus major nests built within nestboxes installed in orchards. Unlike many studied groups, these arthropod communities are not in direct contact with pesticide sprays ...
Okitsu Takashi - - 2013
Halogen bond: The choice of the iodonium complex of pyridines, either IPy2 PF6 or I(coll)2 PF6 (Py=pyridine; coll=2,4,6-trimethylpyridine), was crucial for controlling the iodocyclization/oxidation sequence of α-propargylic glycine derivatives. This reagent-controlled system enabled switchable access to 2,3-dihydropyrroles and pyrroles.
Du Zhi-Yan - - 2013
A family of six genes encoding acyl-CoA-binding proteins (ACBPs), ACBP1-ACBP6, has been characterized in Arabidopsis thaliana. In this study, we demonstrate that ACBP1 promotes abscisic acid (ABA) signaling during germination and seedling development. ACBP1 was induced by ABA, and transgenic Arabidopsis ACBP1-over-expressors showed increased sensitivity to ABA during germination and ...
Garber A J - - 2013
Most physicians are comfortable with initiating basal insulin replacement therapy in their patients with type 2 diabetes who are no longer meeting treatment goals with oral antidiabetic agents. What is more challenging is what to do when treatment goals are no longer being met despite adequate titration of basal insulin. ...
Crowell Elizabeth Faris - - 2013
When a cell divides, it produces two daughter cells initially connected by a cytokinesis bridge, which is eventually cut through abscission. One of the two daughter cells inherits a bridge "remnant", which has been proposed to be degraded by autophagy. The fate and function of remnants is attracting increasing attention, ...
Bohgaki M M Ontario Cancer Institute, University Health Network and Department of Medical Biophysics, University of Toronto, 610 University Avenue, Toronto, Ontario, - - 2013
The serine threonine kinase checkpoint kinase 2 (CHK2) is a DNA damage checkpoint protein important for the ATM-p53 signaling pathway. In addition to its phosphorylation, CHK2 is also ubiquitylated, and both post-translational modifications are important for its function. However, although the mechanisms that regulate CHK2 phosphorylation are well established, those ...
Farrell Christopher-John L - - 2013
Abstract Folate deficiency has been linked to diverse clinical manifestations and despite the importance of accurate assessment of folate status, the best test for routine use is uncertain. Both serum and red cell folate assays are widely available in clinical laboratories; however, red cell folate is the more time-consuming and ...
Chang Jennifer S JS Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, - - 2013
Spt10 is a putative acetyltransferase of Saccharomyces cerevisiae that directly activates the transcription of histone genes. Deletion of SPT10 causes a severe slow growth phenotype, showing that Spt10 is critical for normal cell division. To gain insight into the function of Spt10, we identified mutations that impair or improve the ...
Evans Daniel S DS California Pacific Medical Center Research Institute, San Francisco, CA 94107-1728, - - 2013
To determine the association between common genetic variation in the clock gene pathway and objectively measured acti-graphic sleep and activity rhythm traits. Genetic association study in two population-based cohorts of elderly participants: the Study of Osteoporotic Fractures (SOF) and the Osteoporotic Fractures in Men (MrOS) study. Population-based. SOF participants (n ...
Murray Colleen Crittenden CC Emory University, Rollins School of Public Health, Atlanta, GA 30322, USA. - - 2013
We assessed young African American women's understanding of "dual protection" (DP) (i.e., strategies that simultaneously protect against unintended pregnancies and sexually transmitted diseases [STDs]) and how relationship factors influence their use of DP methods. We conducted 10 focus groups with African American women (n=51) aged 15-24 years in Atlanta, Georgia, ...
Fernandez Sthefanie - - 2013
The bullfrog (Lithobates catesbeianus) is an exotic animal that adapted perfectly to the climatic conditions of Brazil after introduction in the country. These climatic conditions favor the reproduction and fattening of bullfrogs. However, the development of the bullfrog is significantly reduced in colder regions because low temperatures affect the secretion ...
Jagut Marlène - - 2013
The first hours of Drosophila embryogenesis rely exclusively on maternal information stored within the egg during oogenesis. The formation of the egg chamber is thus a crucial step for the development of the future adult. It has emerged that many key developmental decisions are made during the very first stages ...
Staino Carmelina - - 2013
Context-United Network for Organ Sharing (UNOS) 2011 bylaws and Centers for Medicare and Medicaid Services (CMS) regulations require a transplant pharmacist to be an active participant in the care of transplant patients. Transplant centers must be members in good standing with UNOS in order to perform transplants and must be ...
Luo Chunliu - - 2013
We aimed to explore the incidence and persistence of insomnia, the associated risk factors, and the potential bidirectional association of insomnia with depression, anxiety, and sleepiness in rural Chinese adolescents. School-based prospective study. Five high schools in rural China. There were 2,787 adolescents studied. N/A. Insomnia was defined as having ...
Biello Katie Brooks KB The Fenway Institute, Fenway Health, Boston, MA 02215, USA. - - 2013
The age of adolescents at first sexual intercourse is an important risk factor for sexually transmitted diseases (STDs) and adolescent pregnancy. Black adolescents are at higher risk than white adolescents for first sexual intercourse at younger ages as well as STDs and pregnancy. Individual- and family-level factors do not fully ...
Ayabakan Canan - - 2013
OBJECTIVE: We evaluated left ventricular dimensions and aortic arch z-scores in infants who underwent balloon angioplasty (BAP) or surgery for coarctation of aorta (CoA). We searched for risk factors predicting recoarctation. PATIENTS: Between 2007-2011, 27 male and 17 female infants (mean age 2.93 ± 4.78 months, range 2 days-24 months) ...
Dworak Andrzej - - 2013
Well-defined thermosensitive poly[tri(ethylene glycol) monoethyl ether methacrylate] (P(TEGMA-EE)) brushes were synthesized on a solid substrate by the surface-initiated atom transfer radical polymerization of TEGMA-EE. The polymerization reaction was initiated by 2-bromo-2-methylpropionate groups immobilized on the surface of the wafers. The changes in the surface composition, morphology, philicity and thickness that ...
Lorenz Aaron J - - 2013
Allocating resources between population size and replication affects both genetic gain through phenotypic selection and quantitative trait loci detection power and effect estimation accuracy for marker-assisted selection (MAS). It is well known that because alleles are replicated across individuals in quantitative trait loci mapping and MAS, more resources should be ...
Conduit Paul T - - 2013
Centrosomes play an important role in Drosophila melanogaster stem cells, where the different size and activity of the two centrosomes help these cells divide asymmetrically. The molecular basis of the centrosome asymmetry has remained unclear, but new work highlights the centrosomal protein Centrobin as a key player in this process.
Pawl Jean D JD School of Nursing, Georgia State University, Atlanta, GA, USA. - - 2013
To describe the sleep characteristics of family caregivers of individuals with a primary malignant brain tumor (PMBT). Cross-sectional, correlational design using baseline data from a longitudinal study. Neuro-oncology and neurosurgery clinics at an urban tertiary medical center in the United States. 133 family caregivers recruited one to two months following ...
Smylie Lisa L Public Health Agency of Canada, Centre for Communicable Diseases and Infection Control, Ottawa, Ontario, Canada. - - 2013
We developed and validated a set of self-administered, multi-dimensional indicators of sexual health among Canadians aged 16-24 years. This study used a mixed-method qualitative and quantitative approach to develop and validate indicators of sexual health. We used the four-stage Dillman method to identify, focus-test, pilot-test, and validate key metrics to ...
Vaskinn Anja - - 2013
This naturalistic study investigated longitudinal and cross-sectional symptomatic and neurocognitive correlates of social cognition indexed by emotion perception. Participants were 31 persons admitted to a psychiatric emergency ward due to acute psychosis. Positive and negative (i.e., affective blunting and avolition) symptoms were assessed at baseline and 12-month follow-up using the ...
Hirasawa Tatsuya - - 2013
The evolutionary origin of the diaphragm remains unclear, due to the lack of a comparable structure in other extant taxa. However, recent researches into the developmental mechanism of this structure have yielded new insights into its origin. Here we summarize current understanding regarding the development of the diaphragm, and present ...
McCloskey Manabu - - 2013
Inhibiting VEGF improves adult retino/choroido-vascular diseases, but can lead to recurrent intravitreous neovascularization (IVNV), avascular retina (AVA), and retinal detachment in preterm infants with retinopathy of prematurity (ROP). We sought to understand causes of late-onset IVNV and AVA following anti-VEGF using an ROP model. In the Penn model of ROP, ...
Tigges Ulrich - - 2013
BACKGROUND: There is in ncreasing evidence to suggest that pericytes play a crucial role in regulating the remodeling state of blood vessels. As cerebral pericytes are embedded within the extracellular matrix (ECM) of the vascular basal lamina, it is important to understand how individual ECM components influence pericyte-remodeling behavior, and ...
Kugan R - - 2013
Achieving arthrodesis of the ankle can be difficult in the presence of infection, deformity, poor soft tissues and bone loss. We present a series of 48 patients with complex ankle pathology, treated with the Ilizarov technique. Infection was present in 30 patients and 30 had significant deformity before surgery. Outcome was ...
Levine Steven M - - 2013
Evaluation of: Al-Radaideh AM, Wharton SJ, Lim SY et al. Increased iron accumulation occurs in the earliest stages of demyelinating disease: an ultra-high field susceptibility mapping study in clinically isolated syndrome. Mult. Scler. doi:10.1177/1352458512465135 (2012) (Epub ahead of print). Iron has been shown to accumulate in deep gray matter structures ...
Zhong Jim - - 2013
Ampulla of Vater carcinomas are rare malignancies that have been traditionally treated with radical surgical resection. Given the mortality associated with pancreaticoduodenectomy, some patients may benefit from local resection. A single-institution outcomes analysis was performed to define the role of local resection. Patients undergoing local resection (ampullectomy) for ampullary carcinomas ...
Kim Eun Chul - - 2013
ABSTRACT Purpose: To report a case of complete occlusion of the capsulorhexis opening in a DM patient with high hemoglobin A1C level. Methods: A 77-year-old woman with non-insulin-dependent diabetes underwent uncomplicated phacoemulsification in both eyes. One year later, she presented again because of reduced vision (best-corrected visual acuity of 16/20 ...
Lewis Richard A - - 2013
Oxidation of [Li(THF)]2[Co(N[double bond, length as m-dash]CtBu2)4] with 1 equiv. of I2 generates Co(N[double bond, length as m-dash]CtBu2)4 in 85% yield. In the solid-state, this complex exhibits a squashed tetrahedral structure about the Co center. DFT calculations reveal this geometry arises, in part, to maximize ketimide-to-cobalt π-donation.
Gören Jessica L - - 2013
OBJECTIVE To ensure optimal care for patients with schizophrenia, antipsychotic medications must be appropriately prescribed and used. Therefore, the primary objectives of this study were to identify and describe pathways for antipsychotic prescribing, assess the consistency of observed pathways with treatment guidelines, and describe variability across facilities. METHODS Data from ...
Vitetta Luis - - 2013
Uremia is an illness that accompanies kidney failure and chronic kidney disease (CKD). Uremic illness is considered to be due largely to the accumulation of organic waste products that are normally cleared by the kidneys. However, uremic retention solutes are generated in part in the gastrointestinal tract (GIT), with the ...
Li Bin - - 2013
Induction of Endoplasmic Reticulum (ER) stress-mediated apoptosis in cancer cells represents an alternative approach for cancer therapy. Whether fibroblast growth factor 2 (FGF-2)-induced survival signals may interact with ER stress signalling in cancer cells remains elusive. In this work, we showed that pretreatment with FGF-2 decreased the inhibition of DNA ...
Scheiermann Patrick - - 2013
Multidrug-resistant Gram-negative induced sepsis poses an increasing threat to the vulnerable intensive care patient. The study by Toufekoula and colleagues reports the serum and tissue concentration of malondialdehyde (MDA), the toxic end product of lipid peroxidation, during the course of experimental and human Gram-negative sepsis. The complementary results from this ...
Chung Sook Hyun - - 2013
Müller cells, the principal glial cells in the mammalian retina, play an important role in the maintenance of retinal homeostasis. Recent reports suggest that Müller-cell dysfunction may contribute to the pathogenesis of retinal diseases such as idiopathic macular telangiectasia type 2. In the present study, we used microarray to compare ...
Zhang Chun - - 2013
Porous materials: Triptycene-based main-chain organometallic microporous polymers (MOMPs) bearing bis(NHC)-palladium species were synthesized and displayed excellent recoverable catalytic activity in catalyzing Suzuki-Miyaura coupling reactions.
Cole Martin G - - 2013
ABSTRACT Background: Detection of long-term care (LTC) residents at risk of delirium may lead to prevention of this disorder. The primary objective of this study was to determine if the presence of one or more Confusion Assessment Method (CAM) core symptoms of delirium at baseline assessment predicts incident delirium. Secondary ...
Spence John David - - 2013
Abstract Therapy to lower homocysteine with B vitamins does reduce the risk of stroke, if not myocardial infarction. The apparent lack of efficacy of vitamin therapy in most of the large clinical trials was probably determined by the failure to take account of the metabolic deficiency of vitamin B12, which ...
Foster Patricia L - - 2013
By sequencing the genomes of 34 mutation accumulation lines of a mismatch-repair defective strain of that had undergone a total of 12,750 generations, we identified 1625 spontaneous base-pair substitutions spread across the genome. These mutations are not distributed at random but, instead, fall into a wave-like spatial pattern that is ...
Haspeslagh Annelies - - 2013
Context-Self-management is important in ensuring good clinical results in kidney transplant recipients. It was unclear whether the current education program at a single kidney transplant center sufficiently prepares recent transplant recipients for the many complex self-management tasks required.Objective-To evaluate the completeness of and the satisfaction with the current inpatient kidney ...
Goudemand N - - 2013
Sun et al. (Reports, 19 October 2012, p. 366) reconstructed Permian to Middle Triassic equatorial seawater temperatures. After correct temporal positioning of their data points, their presumed trends of temperature changes, and hence their assumption of a one-to-one relationship between putative "lethally hot" seawater temperatures and a disputable equatorial "eclipse" ...
Curie Thomas - - 2013
Besides their well-established role in circadian rhythms, our findings that the forebrain expression of the clock-genes Per2 and Dbp increases and decreases, respectively, in relation to time spent awake suggest they also play a role in the homeostatic aspect of sleep regulation. Here, we determined whether time of day modulates ...
Butler Kathleen - - 2013
Abstract Background: Ticagrelor is a direct-acting, reversibly binding, oral P2Y12 platelet inhibitor that reduces thrombotic cardiovascular events in patients with acute coronary syndrome. Dyspnea is one of the most commonly reported adverse events associated with ticagrelor. Objective: To determine the effect of ticagrelor on pulmonary function in healthy elderly volunteers ...
Ye Meidan - - 2013
Hierarchical TiO2 nanotube arrays grown on Ti foil are yielded by subjecting electrochemically anodized, vertically oriented TiO2 nanotube arrays to hydrothermal processing. The resulting DSSCs exhibit a significantly enhanced power conversion efficiency of 7.24%, which is a direct consequence of the synergy of higher dye loading, superior light-scattering ability, and ...
Andreazza Ana C - - 2013
Bipolar disorder (BD) is a chronic psychiatric illness described by severe changes in mood. Extensive research has been carried out to understand the aetiology and pathophysiology of BD. Several hypotheses have been postulated, including alteration in genetic factors, protein expression, calcium signalling, neuropathological alteration, mitochondrial dysfunction and oxidative stress in ...
Boumhras M - - 2013
Mussels may concentrate pollutants, with possibly significant side effects on human health. Therefore, mussels (Mytilus galloprovincialis) from two sites of the Moroccan Atlantic coast (Jorf Lasfar [JL], an industrial site, and Oualidia [OL], a vegetable-growing area), were subjected to biochemical analyses to quantify the presence of heavy metals (Cd, Cr, ...
Yakovlev Vladislav V - - 2013
Optical sensors for ultrasound detection provide high sensitivity and bandwidth, essential for photoacoustic imaging in clinical diagnostics and biomedical research. Implementing plasmonic metamaterials in a non-resonant regime facilitates sub-nanosecond, highly sensitive detectors while eliminating cumbersome optical alignment necessary for resonant sensors.
Mimura Kana - - 2013
Diet therapy is an important treatment component available for obese cats. In this study, the impact of four commercially available prescription diet regimens [1 for general use and 3 aimed at treating obesity and diabetes mellitus (DM)] on short-term post-prandial serum glucose, insulin, triglyceride and non-esterified fatty acid (NEFA) concentrations ...
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