Search Results
Results 251 - 300 of 3051
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Beuselinck Benoit - - 2013
Background. There are no validated markers that predict outcome in metastatic renal cell cancer (mRCC) patients treated with sunitinib. Recently, single nucleotide polymorphism (SNP) rs9582036 in VEGFR1 has been proposed as a predictor of progression-free survival (PFS) and overall survival (OS) to bevacizumab in patients with pancreatic cancer and rs7993418 ...
Khan Tabrez Alam - - 2013
Arsenic contamination of groundwater is a major threat to human beings globally. Among various methods available for arsenic removal, adsorption is fast, inexpensive, selective, accurate, reproducible and eco-friendly in nature. The present paper describes removal of arsenate from water on zirconium oxide-coated sand (novel adsorbent). In the present work, zirconium ...
Zhang Hechen - - 2013
KEY MESSAGE : This paper is the first to directly link two types of ion channel regulation pathway into an emerging and complex CBL-CIPK signal system in wooden plant. In Arabidopsis thaliana, the calcineurin b-like (CBL) 1 gene has been shown to be necessary in response to abiotic stresses. In ...
Attakpa Eugène S - - 2013
Abstract Background: Bile acids are synthesized in the liver from cholesterol. Method: This study investigated the impact and expression of different carriers of bile acid in the liver and kidneys. Eight-week-old male mice were used, which were fed for 15 days and divided into two groups: 15 mice fed with ...
Cha Jae Myung - - 2013
BACKGROUND: Type 2 diabetes mellitus is associated with an increased risk of colorectal neoplasia. However, association between prediabetes and colorectal adenoma has not been reported. AIMS: The aim of this study was to evaluate the relationship between prediabetes and the presence of colorectal adenomas. METHODS: Consecutive prediabetic subjects who underwent ...
Zahm Daniel S - - 2013
Ambulatory locomotion in the rodent is robustly activated by unilateral infusions into the basal forebrain of type A gamma-aminobutyric acid receptor antagonists, such as bicuculline and picrotoxin. The present study was carried out to better localize the neuroanatomical substrate(s) underlying this effect. To accomplish this, differences in total locomotion accumulated ...
Tranquilli Andrea L - - 2013
Abstract OBJECTIVE: To assess the obstetric outcomes of pregnancy following intracytoplasmic sperm injection (ICSI) using donor oocytes. METHODS: Twenty-six deliveries from oocyte donor ICSI (d-ICSI) were compared to the next two consecutive deliveries from homologous ICSI (h-ICSI group) (n=52) and with the two consecutive deliveries from women older than 40 ...
Seguchi Osamu - - 2013
Infections associated with left ventricular assist devices (LVADs) constitute an important clinical issue because they are difficult to completely eradicate without removal of the LVAD itself and can sometimes be fatal. We encountered a case of extracorporeal LVAD-related candida infection in a patient who was successfully weaned from LVAD support. ...
Xu Jinling - - 2013
BACKGROUND: The objective of this study was to evaluate the retinal nerve fibre layer thickness (RNFLT) and retinal macular thickness (RMT) in esotropic amblyopic children. METHODS: Twenty-one children diagnosed with esotropic amblyopia at Strabismus and Amblyopia Department of Wenzhou Medical College Affiliated Eye Hospital, China, were enrolled in the study. ...
Kocabaş Abdullah - - 2013
Kawasaki Disease (KD) is a vasculitic disease and can affect any organ system in the body. The development of coronary artery aneurysms is the most common and life threatening complication of KD and makes this disease the leading cause of acquired heart disease in children in the developed world. Facial ...
Petracci Elisabetta - - 2013
PURPOSE: To evaluate the effect of excess weight, lifestyle factors, and body image on HRQoL in a sample of school-aged children. METHODS: Cross-sectional data of 4,338 thirteen-year-old children were collected in 2007 as part of the So.N.I.A project, a nutritional surveillance study in a northern Italian region. A two-stage sampling ...
Ormazábal-Toledo Rodrigo - - 2013
We herein report results obtained from an integrated experimental and theoretical study on aromatic nucleophilic substitution (S(N)Ar) reactions of a series of amines towards 1-fluoro-2,4-dinitrobenzene in water. Specific nucleophile-electrophile interactions in the title reactions have been kinetically evaluated. The whole series undergoes S(N)Ar reactions where the formation of the Meisenheimer ...
Ding Chunmei - - 2013
BiVO(4) and many other semiconductor materials are ideal visible light responsive semiconductors, but are insufficient for overall water splitting. Upon loading water oxidation cocatalyst, for example Co-borate (denoted as CoB(i)) used here, onto BiVO(4) photoanode, it is found that not only the onset potential is negatively shifted but also the ...
Ng I-Son - - 2013
Prior studies disclosed that Aeromonas hydrophila NIU01 was a biodecolorization and bioelectricity bacterium which was isolated from a cross-strait of Taiwan. However, enzymatic function, laccase, involved in this strain had never been reported. This first attempt is to explore its laccase activity, the molecular cloning and heterologous recombinant expression in ...
Chtchigrovsky Mélanie - - 2013
A series of bimetallic [(NHC)PtX(2)](2)(diamine) complexes have been prepared as a new chemotype for potential anticancer agents. These complexes display an uncommon set of structural features as far as they combine two bifunctional, trans-configured platinum centers. They display cytotoxic activities in the micromolar range on many cancerous cell lines and ...
Zhang Zhongling - - 2013
Cerebral ischemic stroke is one of the most prevalent diseases in senior individuals. Its therapeutical strategies include anticoagulation, thrombolysis and cell protection. Tissue-type plasminogen activator (t-PA) that interacts with thrombin for the lysis of thrombosis is widely used to treat stroke patients in early stage. The mechanism of action of ...
Nakamura Katsuyuki - - 2013
Introduction: The expression of secreted protein acidic and rich in cysteine (SPARC) in skeletal muscle decreases with age. Here, we examined the role of SPARC in skeletal muscle by reducing its expression. Methods: SPARC expression was suppressed by introducing short interfering RNA (siRNA) into mouse tibialis anterior muscle. Myofiber diameter, ...
Ito Fuminori - - 2013
I studied the myrmicine ant Myrmecina sp. A in West Java, Indonesia, which had the obligately myrmecophilous oribatid mite Aribates javensis in its nests. The oribatid mites cannot survive without ant attendance. The ants rarely eat living mites, but they feed on the mites in case of food shortage and ...
Chen Chih-Jung - - 2013
Sulfonyl-containing aromatic polymers , , , and consisting of a triphenylamine moiety were synthesized and the memory behavior was investigated. By choosing the suitable linkage between the electron donor and acceptor, tunable memory properties (from insulator to different retention time SRAM) could be achieved.
Vilaivan Chotima - - 2013
Hypoxanthine is an unnatural base that can potentially pair with all natural nucleobases. While hypoxanthine in DNA exhibits marginal preference for pairing with cytosine (C), little is known about its pairing behavior in other DNA analogues. In this study, we synthesized a hypoxanthine-containing monomer and incorporated it into pyrrolidinyl peptide ...
Haber Jessica S - - 2013
With steadily rising revenue and large numbers of clinical trials utilizing novel treatment strategies, the field of neuro-oncology is at the core of the growing cancer therapy industry. In June 2012, the Weill Cornell Brain and Tumor Center hosted the first Brain Tumor Biotech Summit as a forum for fostering ...
Sotthewes Kai - - 2013
The energetics and dynamics of the various phases of decanethiolate self-assembled monolayers on Au(111) surfaces was studied with scanning tunneling microscopy. We have observed five different phases of the decanethiolate monolayer on Au(111); four ordered phases (β, δ, χ* and φ) and one disordered phase (ε). We have determined the ...
Dertinger Jennifer J - - 2013
Room temperature ionic liquids (ILs) are effective matrices in secondary ion mass spectrometry (SIMS) and matrix assisted laser desorption ionization (MALDI). In this paper, we examine the role of proton transfer in the mechanism of secondary ion enhancement using IL matrices in SIMS. We employ hydrogenated and deuterated 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) ...
Masciovecchio Stefano - - 2013
he onset of a ureterovaginal fistula is a not frequent, though it represents a dreaded and disabling complication of the pelvic surgery. The literature suggests to perform ureteroneocystostomy associated, if necessary, with a bladder suspension technique to Psoas muscle, or endoscopic procedures of ureteral stenting as the "gold standard" to ...
Wang S-Y - - 2013
Objectives:The aim of this study was to investigate the effect of quercetin on P-glycoprotein (P-gp) transport ability in vivo.Subjects/Methods:Genotype data were available from a total of 165 health volunteers. An open, randomized, two-period crossover clinical trial was performed in eighteen subjects with different MDR1 3435 C/T genotypes. All subjects took ...
Mehta Sapna - - 2013
BACKGROUND: Hospital-acquired infections caused by methicillin-resistant Staphylococcus aureus (MRSA) are a source of morbidity and mortality. S. aureus is the most common pathogen in prosthetic joint infections and the incidence of MRSA is increasing. QUESTIONS/PURPOSES: The purposes of this study were (1) to determine the MRSA prevalence density rate at ...
Lee Myunggu - - 2013
Enzymatic synthesis of biodiesel by the transesterification of canola oil and methanol in high pressure carbon dioxide [HPCO(2): near-critical and supercritical carbon dioxide (NcCO(2) and ScCO(2))] was optimized using response surface methodology (RSM). RSM based on 5-level-5-factor central composite rotatable design (CCRD) was used to evaluate the effects of temperature, ...
Gerrish Kate - - 2013
AIM: To explore experiences of the diagnosis and management of tuberculosis from the perspective of Somali patients and healthcare professionals involved in their care. BACKGROUND: The Somali population has the third highest incidence of tuberculosis occurring in persons born outside the UK. Tuberculosis is a disease with sociocultural as well ...
Sun Raphael C - - 2013
BACKGROUND: Specific data are needed regarding the impact of transfusion on operative complications in pancreatectomy. The objectives of this study were to determine risk factors for transfusion and to evaluate the potential association between transfusion and operative complications in elective pancreatectomy procedures. STUDY DESIGN: We reviewed our institution's pancreatectomy and ...
Lin Daizong - - 2013
The asymmetric synthesis of 3-indolylglycine derivatives was achieved by an oxidative heterocoupling reaction. This method for the selective C-3 functionalization of unprotected indoles with the chiral equivalent of a nucleophilic glycine nickel(ii) complex afforded adducts with high diastereoselectivities. The decomposition of adducts readily afforded 3-indolylglycine derivatives in high yields.
Morimoto Yuma - - 2013
Evidence of an autocatalytic radical chain pathway has been reported in formation of a non-heme iron(iv)-oxo complex by oxidation of an iron(ii) complex with dioxygen and isopropanol in acetonitrile at 298 K. The radical chain reaction is initiated by hydrogen abstraction from isopropanol by the iron(iv)-oxo complex.
Hoang Cam Thuy - - 2013
A method for probing the strength of B-N dative bonds is reported. The activation parameters for nitrogen inversion in a series of azetidines tethered to boronate esters have been quantified by VT-NMR and the measured barriers correlated with data obtained by (11)B NMR, X-ray crystallography and MP2 calculations.
Li Jie - - 2013
Apurinic/apyrimidinic (AP) sites are common DNA lesions arising from spontaneous hydrolysis of the N-glycosidic bond and base-excision repair mechanisms of the modified bases. Due to the strong association of AP site formation with physically/chemically induced DNA damage, quantifying AP sites provides important information for risk assessment of exposure to genotoxins ...
Hernigou Philippe - - 2013
BACKGROUND: It is unclear whether late THA dislocations are related to mechanical impingement or to a biological mechanism that decreases the stability provided by the capsule (eg, inflammation secondary to osteolysis). It is also unknown if alumina-on-alumina bearing couples decrease the risk of late dislocation as a result of the ...
Xing-Mao Zhang - - 2013
Laparoscopic colorectal resection has been extensively accepted for treatment of colorectal cancer. There are several reports about surgeon's age as a factor to have influence on learning laparoscopic approach, and there is no consensus on this point. This study was designed to evaluate the outcomes of laparoscopic colorectal resection in ...
López-Olmeda J F - - 2013
The endocrine axis controlling the stress response displays daily rhythms in many factors such as adrenal sensitivity and cortisol secretion. These rhythms have mostly been described in mammals, whereas they are poorly understood in teleost fish, so that their impact on fish welfare in aquaculture remains unexplored. In the present ...
Ney M - - 2013
BACKGROUND: Malnutrition is a common and clinically significant problem in patients with cirrhosis. The impact of nutritional therapy remains unclear. AIM: To provide an up-to-date systematic review and meta-analysis of RCTs of oral or enteral nutritional supplementation (ONS or ENS) on nutritional and clinical outcomes in adult patients with cirrhosis. ...
Plummer Ruth - - 2013
PURPOSE: poly(ADP ribose) polymerase inhibition has been shown to potentiate the cytotoxicity of DNA damaging agents. A phase I study of rucaparib and temozolomide showed that full-dose temozolomide could be given during PARP inhibition. We report the results of a phase II study of intravenous rucaparib 12 mg/m(2) and oral temozolomide ...
Li Ning - - 2013
The complete mitochondrial genome of the Pacific sand lance Ammodytes hexapterus was determined. The entire sequence is 16,527 bp in length assembling 22 tRNAs, 2 rRNAs and 13 protein-coding genes as well as the putative control region and O(L). The gene arrangement and component are identical to those of canonical vertebrate ...
de Castro Leonardo D - - 2013
The Philippine government officially responded to the Declaration of Istanbul on Organ Trafficking and the related WHO Guidelines on organ transplantation by prohibiting all transplants to foreigners using Filipino organs. However, local tourists have escaped the regulatory radar, leaving a very wide gap in efforts against human trafficking and transplant ...
Wang Y - - 2013
Catechol-O-methyltransferase (COMT) Val158Met (rs4680) polymorphism plays a crucial role in regulating brain dopamine level. Converging evidence from Caucasian samples showed that, compared with rs4680 Val allele, the Met allele was linked to lower COMT activity, which in turn was linked to better cognitive performance such as working memory (WM) and ...
Itoh Kyoto - - 2013
Lethal congenital contracture syndrome (LCCS) is an autosomal recessive disease, characterized by the fetal akinesia phenotype, with multiple contractures of joints and degeneration of motor neurons in the spinal cord as the main neuropathological findings [1, 2, 3, 4, 5]. Recent studies have shown that the defective gene underlying the ...
Miao Rong - - 2013
A novel, facile and effective method for modification of SiNWs or SiNW arrays has been developed. In this method, reaction between reductive Si-H bonds on the surface of SiNWs and the aldehyde group containing in organic molecules has been used for immobilization of organic molecules onto the surface of SiNW ...
Song Z - - 2013
OBJECTIVE: This retrospective analysis evaluates the clinical outcomes of extensive-stage small cell lung cancer (SCLC) patients who received second-line chemotherapy after platinum-based first-line chemotherapy, especially focusing on efficacy and toxicity between single-agent and combination chemotherapy. METHODS: We retrospectively reviewed 193 patients who received second-line chemotherapy for extensive-stage SCLC. Patients relapsing ...
Wagner Michael - - 2013
Interactions between the enteric nervous system and the immune system are suggested to play an important role in the pathophysiology of inflammatory bowel disease (IBD). This study aims to determine if chromogranin A (CgA), chromogranin B (CgB), and secretoneurin (SN) are detectable in feces (F) from patients with collagenous colitis ...
Frauenfelder F - - 2013
ACCESSIBLE SUMMARY: The use of a standardized nursing language enhances nursing quality. The Nursing Interventions Classification (NIC) considers any treatment by nurses that improve patient outcomes. The present study identifies nursing interventions in journal articles on adult psychiatric inpatient nursing care. These interventions are compared with the NIC entries to ...
Lu Lingli - - 2013
Sedum alfredii is one of a few species known to hyperaccumulate zinc (Zn) and cadmium (Cd). Xylem transport and phloem remobilization of Zn in hyperaccumulating (HP) and nonhyperaccumulating (NHP) populations of S. alfredii were compared. Micro-X-ray fluorescence (μ-XRF) images of Zn in the roots of the two S. alfredii populations suggested an ...
Tsao Sean W - - 2013
Age-related macular degeneration (AMD) is a leading cause of blindness worldwide for which preventative therapies are few. Evidence suggesting shared common risk factors and mirrored pathophysiology between cardiovascular disease and AMD led to the hypothesis that hydroxymethylglutaryl-CoA reductase inhibitors (statins) could be helpful in preventing AMD. For over a decade, ...
Terashima Yoshitaka - - 2013
Boron-modified pyrrole-based anion receptors (catechol-boron and diphenylboron dipyrrolyldiketone derivatives) formed planar receptor-anion complexes, leading to charge-by-charge assemblies with planar cations, as in the corresponding difluoroboron derivative.
Neophytou Andreas M - - 2013
Ambient particulate matter (PM) has been shown to have short- and long-term effects on cardiorespiratory mortality and morbidity. Most of the risk is associated with fine PM (PM(2.5)); however, recent evidence suggests that desert dust outbreaks are major contributors to coarse PM (PM(10-2.5)) and may be associated with adverse health ...
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