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Basu Dipannita - - 2013
The human dopamine D2L receptor has significant implications in neurological and neuropsychiatric disorders such as Parkinson's disease and schizophrenia. Detailed structural knowledge of this receptor is limited due to its highly hydrophobic nature, which leads to protein aggregation and host toxicity when expressed in cellular systems. The newly emerging field ...
Tabart Jeremy - - 2013
Rearing pests or parasites of very small size in the absence of their living host is a challenge for behavioural, physiological and pathological studies. For feeding Varroa destructor, an ectoparasitic mite of Apis mellifera, a confinement space with a membrane separating the nutritive solution and the space was designed. The ...
Keene Tony D - - 2013
Dynamically porous metal-organic frameworks (MOFs) with a chiral quartz-based structure have been synthesized from the multidentate ligand 2,2'-dihydroxybiphenyl-4,4'-dicarboxylate (H(2)diol). Compounds [Ni(ii)(H(2)diol)(S)(2)]·xS (where S = DMF or DEF) show marked changes in 77 K N(2) uptake between partially desolvated [Ni(ii)(H(2)diol)(S)(2)] (only the pore solvent is removed) and fully desolvated [Ni(ii)(H(2)diol)] forms. ...
Delgado-Plasencia Luciano - - 2013
PURPOSES: Methylenetetrahydrofolate reductase (MTHFR) plays a key role in folate metabolism, and folate is implicated in carcinogenesis by its role in DNA methylation, repair, and synthesis. We analyzed the impact of MTHFR C677T polymorphism in colorectal cancer in a region of the Tenerife Island whose population has a history of ...
Holme Inger Baeksted - - 2013
One of the major concerns of the general public about transgenic crops relates to the mixing of genetic materials between species that cannot hybridize by natural means. To meet this concern, the two transformation concepts cisgenesis and intragenesis were developed as alternatives to transgenesis. Both concepts imply that plants must ...
Chordia P - - 2013
BACKGROUND: Placement of ureteral stents at the time of renal transplantation is thought to decrease the incidence of postoperative complications, such as anastomotic leakage and stenosis. However, stents may also predispose to post-transplantation urinary tract infection, which can lead to increased risks of graft dysfunction, sepsis, and death. The aim ...
Van Wonderen Jessica H - - 2013
Bacterial nitric oxide reductase (NOR) is a major source of the powerful greenhouse gas N2O. NorBC from Paracoccus denitrificans is a heterodimeric multi-heme transmembrane complex. The active site, in NorB, comprises high-spin heme b3 in close proximity to non-heme iron, FeB. In oxidised NorBC, the active-site is EPR-silent due to ...
Millen Aletta M E - - 2013
To determine whether exercise training-induced decreases in blood pressure (BP) can be explained by decreases in aortic systolic pressure augmentation in overweight or obese individuals. Thirty-five sedentary or recreationally active men and women (30-57 years) who were either overweight (40 %) or obese (60 %) completed 6 weeks of exercise training (≥3 days/week; stationary bike ...
Oluboyede Yemi - - 2013
AIM: The aim of this study is to explore the dimensionality of the CASP-19-a quality-of-life measure for early old age-and to assess the stability of the item locations over time and changes in person measures. METHODS: The Rasch partial credit model was applied to the CASP-19 data obtained from Waves ...
Yürekli Vedat Ali - - 2013
Dural arteriovenous fistulas (DAVFs) are rare lesions. The most common locations of DAVFs are cavernous, sigmoid and transverse sinuses. Anterior cranial fossa is one of the less frequent placement for DAVFs and the risk of hemorrhage in this region is increased. Reported hemorrhage risks have been ranged from 62 to ...
Chen Huanchen - - 2013
This paper presents the behaviors of a liquid bridge when being compressed and stretched in a quasi-static fashion between two solid surfaces that have contact angle hysteresis (CAH). A theoretical model is developed to obtain the profiles of the liquid bridge given a specific separation between the surfaces. Different from ...
Atta Ananta Kumar - - 2013
The Hg(II)-specific intramolecular cyclization reaction of ethynyl phenols was carried out for the first time in semiaqueous media at ambient temperature. The reaction unit (ethynyl phenol) was coupled with a malononitrile derivative (signal unit), which afforded the chromogenic Hg(II) indicator 7. The reaction of the chromogenic Hg(II) indicator 7 was ...
Sattler E C - - 2013
we thank Lacey et al. for their interesting and very welcome thoughts concerning our article on the usefulness of confocal laser scanning microscopy (CLSM) in the quantification of demodex mites and for their excellent pictures of Demodex mites seen under the light microscope after extraction using the standardized skin surface ...
- - 2013
Objective: The goal of this prospective and double-blind study was to compare the efficacy of amitriptyline and topiramate for the prevention of pediatric chronic daily headache (CDH). Research design and methods: Fifty-seven children (aged 9-16 years) diagnosed with CDH were randomly assigned to two groups: Group A (n = 29 patients) ...
Park Ji Hoon - - 2013
The stabilities of a blending type organic thin-film transistor with phase-separated TIPS-pentacene channel layer were characterized under the conditions of negative-bias-stress (NBS) and positive-bias-stress (PBS). During NBS, threshold voltage (V(th)) shifts noticeably. NBS-imposed devices revealed interfacial trap density-of-states (DOS) at 1.56 and 1.66 eV while initial device showed the DOS ...
Beuselinck Benoit - - 2013
Background. There are no validated markers that predict outcome in metastatic renal cell cancer (mRCC) patients treated with sunitinib. Recently, single nucleotide polymorphism (SNP) rs9582036 in VEGFR1 has been proposed as a predictor of progression-free survival (PFS) and overall survival (OS) to bevacizumab in patients with pancreatic cancer and rs7993418 ...
Khan Tabrez Alam - - 2013
Arsenic contamination of groundwater is a major threat to human beings globally. Among various methods available for arsenic removal, adsorption is fast, inexpensive, selective, accurate, reproducible and eco-friendly in nature. The present paper describes removal of arsenate from water on zirconium oxide-coated sand (novel adsorbent). In the present work, zirconium ...
Zhang Hechen - - 2013
KEY MESSAGE : This paper is the first to directly link two types of ion channel regulation pathway into an emerging and complex CBL-CIPK signal system in wooden plant. In Arabidopsis thaliana, the calcineurin b-like (CBL) 1 gene has been shown to be necessary in response to abiotic stresses. In ...
Attakpa Eugène S - - 2013
Abstract Background: Bile acids are synthesized in the liver from cholesterol. Method: This study investigated the impact and expression of different carriers of bile acid in the liver and kidneys. Eight-week-old male mice were used, which were fed for 15 days and divided into two groups: 15 mice fed with ...
Cha Jae Myung - - 2013
BACKGROUND: Type 2 diabetes mellitus is associated with an increased risk of colorectal neoplasia. However, association between prediabetes and colorectal adenoma has not been reported. AIMS: The aim of this study was to evaluate the relationship between prediabetes and the presence of colorectal adenomas. METHODS: Consecutive prediabetic subjects who underwent ...
Zahm Daniel S - - 2013
Ambulatory locomotion in the rodent is robustly activated by unilateral infusions into the basal forebrain of type A gamma-aminobutyric acid receptor antagonists, such as bicuculline and picrotoxin. The present study was carried out to better localize the neuroanatomical substrate(s) underlying this effect. To accomplish this, differences in total locomotion accumulated ...
Tranquilli Andrea L - - 2013
Abstract OBJECTIVE: To assess the obstetric outcomes of pregnancy following intracytoplasmic sperm injection (ICSI) using donor oocytes. METHODS: Twenty-six deliveries from oocyte donor ICSI (d-ICSI) were compared to the next two consecutive deliveries from homologous ICSI (h-ICSI group) (n=52) and with the two consecutive deliveries from women older than 40 ...
Seguchi Osamu - - 2013
Infections associated with left ventricular assist devices (LVADs) constitute an important clinical issue because they are difficult to completely eradicate without removal of the LVAD itself and can sometimes be fatal. We encountered a case of extracorporeal LVAD-related candida infection in a patient who was successfully weaned from LVAD support. ...
Xu Jinling - - 2013
BACKGROUND: The objective of this study was to evaluate the retinal nerve fibre layer thickness (RNFLT) and retinal macular thickness (RMT) in esotropic amblyopic children. METHODS: Twenty-one children diagnosed with esotropic amblyopia at Strabismus and Amblyopia Department of Wenzhou Medical College Affiliated Eye Hospital, China, were enrolled in the study. ...
Kocabaş Abdullah - - 2013
Kawasaki Disease (KD) is a vasculitic disease and can affect any organ system in the body. The development of coronary artery aneurysms is the most common and life threatening complication of KD and makes this disease the leading cause of acquired heart disease in children in the developed world. Facial ...
Petracci Elisabetta - - 2013
PURPOSE: To evaluate the effect of excess weight, lifestyle factors, and body image on HRQoL in a sample of school-aged children. METHODS: Cross-sectional data of 4,338 thirteen-year-old children were collected in 2007 as part of the So.N.I.A project, a nutritional surveillance study in a northern Italian region. A two-stage sampling ...
Ormazábal-Toledo Rodrigo - - 2013
We herein report results obtained from an integrated experimental and theoretical study on aromatic nucleophilic substitution (S(N)Ar) reactions of a series of amines towards 1-fluoro-2,4-dinitrobenzene in water. Specific nucleophile-electrophile interactions in the title reactions have been kinetically evaluated. The whole series undergoes S(N)Ar reactions where the formation of the Meisenheimer ...
Ding Chunmei - - 2013
BiVO(4) and many other semiconductor materials are ideal visible light responsive semiconductors, but are insufficient for overall water splitting. Upon loading water oxidation cocatalyst, for example Co-borate (denoted as CoB(i)) used here, onto BiVO(4) photoanode, it is found that not only the onset potential is negatively shifted but also the ...
Ng I-Son - - 2013
Prior studies disclosed that Aeromonas hydrophila NIU01 was a biodecolorization and bioelectricity bacterium which was isolated from a cross-strait of Taiwan. However, enzymatic function, laccase, involved in this strain had never been reported. This first attempt is to explore its laccase activity, the molecular cloning and heterologous recombinant expression in ...
Chtchigrovsky Mélanie - - 2013
A series of bimetallic [(NHC)PtX(2)](2)(diamine) complexes have been prepared as a new chemotype for potential anticancer agents. These complexes display an uncommon set of structural features as far as they combine two bifunctional, trans-configured platinum centers. They display cytotoxic activities in the micromolar range on many cancerous cell lines and ...
Zhang Zhongling - - 2013
Cerebral ischemic stroke is one of the most prevalent diseases in senior individuals. Its therapeutical strategies include anticoagulation, thrombolysis and cell protection. Tissue-type plasminogen activator (t-PA) that interacts with thrombin for the lysis of thrombosis is widely used to treat stroke patients in early stage. The mechanism of action of ...
Nakamura Katsuyuki - - 2013
Introduction: The expression of secreted protein acidic and rich in cysteine (SPARC) in skeletal muscle decreases with age. Here, we examined the role of SPARC in skeletal muscle by reducing its expression. Methods: SPARC expression was suppressed by introducing short interfering RNA (siRNA) into mouse tibialis anterior muscle. Myofiber diameter, ...
Ito Fuminori - - 2013
I studied the myrmicine ant Myrmecina sp. A in West Java, Indonesia, which had the obligately myrmecophilous oribatid mite Aribates javensis in its nests. The oribatid mites cannot survive without ant attendance. The ants rarely eat living mites, but they feed on the mites in case of food shortage and ...
Chen Chih-Jung - - 2013
Sulfonyl-containing aromatic polymers , , , and consisting of a triphenylamine moiety were synthesized and the memory behavior was investigated. By choosing the suitable linkage between the electron donor and acceptor, tunable memory properties (from insulator to different retention time SRAM) could be achieved.
Vilaivan Chotima - - 2013
Hypoxanthine is an unnatural base that can potentially pair with all natural nucleobases. While hypoxanthine in DNA exhibits marginal preference for pairing with cytosine (C), little is known about its pairing behavior in other DNA analogues. In this study, we synthesized a hypoxanthine-containing monomer and incorporated it into pyrrolidinyl peptide ...
Haber Jessica S - - 2013
With steadily rising revenue and large numbers of clinical trials utilizing novel treatment strategies, the field of neuro-oncology is at the core of the growing cancer therapy industry. In June 2012, the Weill Cornell Brain and Tumor Center hosted the first Brain Tumor Biotech Summit as a forum for fostering ...
Sotthewes Kai - - 2013
The energetics and dynamics of the various phases of decanethiolate self-assembled monolayers on Au(111) surfaces was studied with scanning tunneling microscopy. We have observed five different phases of the decanethiolate monolayer on Au(111); four ordered phases (β, δ, χ* and φ) and one disordered phase (ε). We have determined the ...
Dertinger Jennifer J - - 2013
Room temperature ionic liquids (ILs) are effective matrices in secondary ion mass spectrometry (SIMS) and matrix assisted laser desorption ionization (MALDI). In this paper, we examine the role of proton transfer in the mechanism of secondary ion enhancement using IL matrices in SIMS. We employ hydrogenated and deuterated 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) ...
Masciovecchio Stefano - - 2013
he onset of a ureterovaginal fistula is a not frequent, though it represents a dreaded and disabling complication of the pelvic surgery. The literature suggests to perform ureteroneocystostomy associated, if necessary, with a bladder suspension technique to Psoas muscle, or endoscopic procedures of ureteral stenting as the "gold standard" to ...
Wang S-Y - - 2013
Objectives:The aim of this study was to investigate the effect of quercetin on P-glycoprotein (P-gp) transport ability in vivo.Subjects/Methods:Genotype data were available from a total of 165 health volunteers. An open, randomized, two-period crossover clinical trial was performed in eighteen subjects with different MDR1 3435 C/T genotypes. All subjects took ...
Lee Myunggu - - 2013
Enzymatic synthesis of biodiesel by the transesterification of canola oil and methanol in high pressure carbon dioxide [HPCO(2): near-critical and supercritical carbon dioxide (NcCO(2) and ScCO(2))] was optimized using response surface methodology (RSM). RSM based on 5-level-5-factor central composite rotatable design (CCRD) was used to evaluate the effects of temperature, ...
Gerrish Kate - - 2013
AIM: To explore experiences of the diagnosis and management of tuberculosis from the perspective of Somali patients and healthcare professionals involved in their care. BACKGROUND: The Somali population has the third highest incidence of tuberculosis occurring in persons born outside the UK. Tuberculosis is a disease with sociocultural as well ...
Sun Raphael C - - 2013
BACKGROUND: Specific data are needed regarding the impact of transfusion on operative complications in pancreatectomy. The objectives of this study were to determine risk factors for transfusion and to evaluate the potential association between transfusion and operative complications in elective pancreatectomy procedures. STUDY DESIGN: We reviewed our institution's pancreatectomy and ...
Lin Daizong - - 2013
The asymmetric synthesis of 3-indolylglycine derivatives was achieved by an oxidative heterocoupling reaction. This method for the selective C-3 functionalization of unprotected indoles with the chiral equivalent of a nucleophilic glycine nickel(ii) complex afforded adducts with high diastereoselectivities. The decomposition of adducts readily afforded 3-indolylglycine derivatives in high yields.
Morimoto Yuma - - 2013
Evidence of an autocatalytic radical chain pathway has been reported in formation of a non-heme iron(iv)-oxo complex by oxidation of an iron(ii) complex with dioxygen and isopropanol in acetonitrile at 298 K. The radical chain reaction is initiated by hydrogen abstraction from isopropanol by the iron(iv)-oxo complex.
Hoang Cam Thuy - - 2013
A method for probing the strength of B-N dative bonds is reported. The activation parameters for nitrogen inversion in a series of azetidines tethered to boronate esters have been quantified by VT-NMR and the measured barriers correlated with data obtained by (11)B NMR, X-ray crystallography and MP2 calculations.
Li Jie - - 2013
Apurinic/apyrimidinic (AP) sites are common DNA lesions arising from spontaneous hydrolysis of the N-glycosidic bond and base-excision repair mechanisms of the modified bases. Due to the strong association of AP site formation with physically/chemically induced DNA damage, quantifying AP sites provides important information for risk assessment of exposure to genotoxins ...
Hernigou Philippe - - 2013
BACKGROUND: It is unclear whether late THA dislocations are related to mechanical impingement or to a biological mechanism that decreases the stability provided by the capsule (eg, inflammation secondary to osteolysis). It is also unknown if alumina-on-alumina bearing couples decrease the risk of late dislocation as a result of the ...
Xing-Mao Zhang - - 2013
Laparoscopic colorectal resection has been extensively accepted for treatment of colorectal cancer. There are several reports about surgeon's age as a factor to have influence on learning laparoscopic approach, and there is no consensus on this point. This study was designed to evaluate the outcomes of laparoscopic colorectal resection in ...
López-Olmeda J F - - 2013
The endocrine axis controlling the stress response displays daily rhythms in many factors such as adrenal sensitivity and cortisol secretion. These rhythms have mostly been described in mammals, whereas they are poorly understood in teleost fish, so that their impact on fish welfare in aquaculture remains unexplored. In the present ...
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