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Ribeiro Marcos A - - 2013
Bi-stable molecular systems presenting valence tautomerism are associated with the development of new functional materials, which can be used for applications in organic electric conductors, optoelectronic and molecular magnetic devices. The properties of these materials can be adjusted with slight chemical changes and can be induced by external stimuli. Typical ...
Lin Miao - - 2013
We recently showed that Toll-like receptor (TLR) TLR4 was overexpressed in the human diabetic kidney, which could promote tubular inflammation. Here we explored whether the TLR4 antagonist, CRX-526, has therapeutic potential to attenuate renal injuries and slow the progression of advanced diabetic nephropathy in wild-type and endothelial nitric oxide synthase ...
Réus Gislaine Z - - 2013
Studies have shown a relationship between energy metabolism and methylphenidate (MPH); however, there are no studies evaluating the effects of MPH in Krebs cycle. So, we investigated if MPH treatment could alter the activity of citrate synthase (CS), malate dehydrogenase (MD), and isocitrate dehydrogenase (ID) in the brain of young ...
Jazini Mohammadhadi - - 2013
Escherichia coli is widely used host for the intracellular expression of many proteins. However, in some cases also secretion of protein from periplasm was observed. Improvement of both intracellular and extracellular production of recombinant protein in E. coli is an attractive goal in order to reduce production cost and increase ...
Moya Mireya - - 2013
During spring of 2009, a new influenza virus AH1N1 spread in the world causing acute respiratory illness and death, resulting in the first influenza pandemic since 1968. Blood levels of potentially-toxic and essential elements of 40 pneumonia and confirmed AH1N1 were evaluated against two different groups of controls, both not ...
Salmeri M - - 2013
The key aspect of neonatal meningitis is related to the ability of pathogens to invade the blood-brain barrier (BBB) and to penetrate the central nervous system. In the present study we show that, in an in vitro model of BBB, on the basis of co-culturing primary bovine brain endothelial cells ...
Furuya Takefumi - - 2013
To determine the prevalence of vitamin D deficiency and associations with clinical characteristics in Japanese patients with rheumatoid arthritis (RA), serum 25(OH)D levels, laboratory data, and clinical data were obtained from 4,793 patients with RA (4,075 women, 718 men, mean age 59.7 years) who participated in the Institute of Rheumatology Rheumatoid ...
Marcellin Fabienne - - 2013
AIMS: Studying alcohol abuse impact, as measured by physicians' perceptions and patients' self-reports, on HIV virological rebound among patients chronically co-infected with HIV and hepatitis C virus (HCV). DESIGN: Cohort study. SETTING: Seventeen French hospitals. PARTICIPANTS: 512 patients receiving antiretroviral therapy (ART) with an undetectable initial HIV viral load and ...
Banerjee Arnab - - 2013
A visible light excitable rhodamine based probe operates as a SCN(-) selective fluorescent "turn-on" sensor for living cell imaging with a detection limit of 0.01 μM, which is much lower than the normal SCN(-) level in the human body. A "lock" and "key" model has been proposed to explain the ...
Stergiou-Kita Mary - - 2013
Purpose A systematic literature review was undertaken to gather evidence to develop a guideline for vocational evaluation following burn injuries (BI). This review aimed to identify the key processes evaluators should follow and the key factors they should consider when completing such evaluations. Methods Steps outlined in Cochrane Handbook of ...
Sawa Yoshiki - - 2013
Although legislation regarding organ transplantation from brain-dead donors in Japan was approved in 1997, no heart-lung transplantation procedures were performed for some time. Herein, we report the first case of successful heart-lung transplantation in Japan. The recipient was a 35-year-old man with Eisenmenger syndrome, caused by a double outlet right ...
Christison-Lagay Emily - - 2013
BACKGROUND: Thymectomy is a well-established treatment for generalized myasthenia gravis in adults, but predictors of long-term efficacy and the optimum timing for intervention in juvenile myasthenia remain controversial. PURPOSE: To review the preoperative presentation, surgical experience, and long-term neuromuscular follow-up in patients undergoing thoracoscopic thymectomy in a single institution. METHODS: ...
Ozturk Ferhat - - 2013
ABSTRACT: BACKGROUND: In humans, cleft palate (CP) accounts for one of the largest number of birth defects with a complex genetic and environmental etiology. TGFbeta3 has been established as an important regulator of palatal fusion in mice and it has been shown that TGFbeta3-null mice exhibit CP without any other ...
Videlock E J - - 2013
BACKGROUND: Dyssynergic defecation (DD) results from inadequate relaxation of the pelvic floor on attempted defecation. The prevalence of DD in patients with chronic constipation (CC) is not certain. Aims of this study are to estimate the prevalence of abnormal findings associated with DD across testing modalities in patients referred for ...
Sekeroglu Mehmet Ali - - 2013
Various ocular conditions which leadto vision loss in different degrees such as cataract, ischemic optic neuropathy and retinopathy are closely related to diabetes mellitus. (1-3) Diabetic patients may also suffer from transient or permanent changes in refraction. (4-5) We describe here an extreme case of transient hyperopia in a newly ...
Montgomery M K - - 2013
AIMS/HYPOTHESIS: Metabolic disorders are commonly investigated using knockout and transgenic mouse models. A variety of mouse strains have been used for this purpose. However, mouse strains can differ in their inherent propensities to develop metabolic disease, which may affect the experimental outcomes of metabolic studies. We have investigated strain-dependent differences ...
Li Qiang - - 2013
The ratio between FABP5 and CRABPII determines cellular response to physiological level of retinoic acid; tumor cells undergo proliferation with high level of FABP5 and apoptosis with high level of CRABPII. We intended to study FABP5 and CRABPII expression in craniopharyngiomas, to establish craniopharyngioma cell model using explants method, and ...
Shaheen Shagufta - - 2013
Mucosa-associated lymphoid tissue (MALT)-type lymphomas most commonly occur in the stomach and have been associated with Helicobacter pylori infection. However, MALT-type lymphoma of the colon is a rare entity. It commonly manifests with symptoms of weight loss, low-grade fever, constipation, melena, and hematochezia. Unlike gastric lymphoma, it is difficult to ...
Fahy Michael - - 2013
BACKGROUND: Increasing birth rates have raised questions for policy makers and hospital management about the economic costs of childbirth. OBJECTIVE: The purpose of this article is to identify and review all existing scientific studies in relation to the economic costs of alternative modes of childbirth delivery and highlight deficiencies in ...
Roth Christian - - 2013
The actinobacterium Rhodococcus opacus 1CP possesses a so far unique variant of the modified 3-oxoadipate pathway for 3-chlorocatechol degradation. One important feature is the novel dehalogenase ClcF, which converts (4R,5S) 5-chloromuconolactone to E-dienelactone. ClcF is related to muconolactone isomerase (MLI, EC 5.3.3.4). The enzyme has a ferredoxin-type fold and forms ...
Rodríguez-Vivas R I - - 2013
Rhipicephalus microplus is the most economically important cattle tick in the Mexican tropics. Wild ungulate species, including red deer (Cervus elaphus), are gaining popularity in diversified livestock ranching operations in Mexico. However, there is no information available on the susceptibility of red deer to infestation with the cattle tick, R. ...
Li Ya-Jun - - 2013
The Glasgow Prognostic Score (GPS), an inflammation-based prognostic score including C-reactive protein and albumin, shows significant prognostic value in several types of solid tumors. The prognostic value of GPS in lymphoma remains unclear. We performed this study to evaluate the prognostic significance of GPS in extranodal natural killer (NK)/T-cell lymphoma ...
Guan S - - 2013
BACKGROUND: The present study was undertaken to develop an in-house enzyme-linked immunosorbent assay (ELISA) using human leukocyte antigen class II restricted epitopes to test circulating autoantibodies to CD25 as a biomarker for esophageal cancer. METHODS: A total of 97 patients with esophageal squamous cell carcinoma (ESCC) and 226 healthy subjects ...
Chang Yu-Cheng - - 2013
The effects of the 4-tert-butylpyridine (TBP) additive in the electrolyte on photovoltaic performance of two push-pull porphyrin sensitizers (YD12 and YD12CN) were examined. Addition of TBP significantly increased the open-circuit voltage (V(OC)) for YD12 (from 550 to 729 mV) but it was to a lesser extent for YD12CN (from 544 ...
Quevedo Ivan R - - 2013
A clear understanding of the factors controlling the deposition behavior of engineered nanoparticles (ENPs), such as quantum dots (QDs), is necessary for predicting their transport and fate in natural subsurface environments and in water filtration processes. A quartz crystal microbalance with dissipation monitoring (QCM-D) was used to study the effect ...
Fitzgerald J E F - - 2013
BACKGROUND: Fellowship posts are increasingly common and offer targeted opportunities for training and personal development. Despite international demand, there is little objective information quantifying this effect or the motivations behind undertaking such a post. The present study investigated surgical trainees' fellowship aims and intentions. METHODS: An electronic, 38-item, self-administered questionnaire ...
Kumar Monisha A - - 2013
BACKGROUND AND PURPOSE: Red blood cell transfusion (RBCT) may increase the risk of thrombotic events (TE) in patients with subarachnoid hemorrhage (SAH) through changes induced by storage coupled with SAH-related hypercoagulability. We sought to investigate the association between RBCT and the risk of TE in patients with SAH. METHODS: 205 ...
Dong Hao - - 2013
With abundant energy levels of 4f electron configurations, trivalent lanthanide ions (Ln(3+)) are endowed with unique and fascinating luminescent properties. Inheriting the native transition behaviour of the lanthanide ions, Ln(3+) based nanomaterials have aroused great interest for a wide range of applications, including lighting and displays, optical fibers and amplifiers, ...
Dheda Shehreen S - - 2013
Ti alloys, such as Ti6Al4V, are currently used in biomedical and dental implant applications. Ti alloys are used because they are stronger than commercially pure (CP) Ti due to the presence of alloying elements. However, toxicity of alloying elements during long-term use of implants is of concern. Another means of ...
Chen Lichin - - 2013
Disease management is a program which attempts to overcome the fragmentation of healthcare system and improve the quality of care. Many studies have proven the effectiveness of disease management. However, the case managers were spending the majority of time in documentation, coordinating the members of the care team. They need ...
Biancardi Alessandro - - 2013
The fluorescent probe 4',6-diamidino-2-phenylindole (DAPI) is a dye known to interact with polynucleotides in a non-univocal manner, both intercalation and minor groove binding modes being possible, and to specifically change its photophysical properties according to the different environments. To investigate this behavior, quantum-mechanical calculations using time-dependent density functional theory (TDDFT), ...
Liu Jin - - 2013
Isochrysis is a genus of marine unicellular microalgae that produces docosahexaenoic acid (DHA, C22:6), a very long chain polyunsaturated fatty acid (PUFA) of significant health and nutritional value. Mass cultivation of Isochrysis for DHA production for human consumption has not been established due to disappointing low DHA productivity obtained from ...
Starkewolf Zane B - - 2013
Enhanced cellular toxicity was observed using X-ray irradiated nanoparticle drug carriers (NDC) consisting of doxorubicin (DOX) conjugated to DNA strands attached to the surface of gold nanoparticles. Kinetic studies showed that X-rays, acting as a triggering modality, generated reactive oxygen species to break DNA strands and release DOX.
Kalikka J - - 2013
Thin films of gallium/antimony alloys are promising candidates for phase change memories requiring rapid crystallization at high crystallization temperatures. Prominent examples are the stoichiometric form GaSb and alloys near the eutectic composition GaSb(7), but little is known about their amorphous structures or the differences between the 'as-deposited' (AD) and 'melt-quenched' ...
Artyushkova K - - 2013
Our results validate the use of independent DFT predicted BE shifts for defect identification and constraining ambient pressure XPS observations for Me-N(x) moieties in pyrolyzed carbon based ORR electrocatalysts. This supports the understanding of such catalysts as vacancy-and-substitution defects in a graphene-like matrix.
Gmidène A - - 2013
8p21.3 deletion was recently characterized in B cell lymphoma suggesting that TRAIL-R1 and TRAIL-R2 may be the target of the deletion and act as dosage-dependent tumor suppressor genes. As multiple myeloma is a plasma cell malignancy originating from B-lineage clonogenic cells, the idea was why do not evaluate this deletion ...
Sabrina Siamer - - 2013
The bacterium Erwinia amylovora causes fire blight, an invasive disease that threatens apple trees, pear trees and other plants of the Rosaceae family. E. amylovora pathogenicity relies on a type III secretion system and on a single effector DspA/E. This effector belongs to the widespread AvrE family of effectors whose ...
Javid Gul - - 2013
BACKGROUND: The purpose of the present study was to determine the etiology, management, and outcome of acute pancreatitis (AP) in children in an endemic area of hepatobiliary ascariasis (HBA). METHODS: This was a prospective, hospital-based study over a 9-year period that included 156 children younger than 12 years of age who ...
Burcharth J - - 2013
BACKGROUND: Groin hernia has been proposed to be hereditary; however, a clear hereditary pattern has not been established yet. The purpose of this review was to analyze studies evaluating family history and inheritance patterns and to investigate the possible heredity of groin hernias. METHODS: A literature search in the MEDLINE ...
Oberley Matthew J - - 2013
Cobalamin (vitamin B12) deficiency is a common cause of megaloblastic anemia in Western populations. Laboratory evaluation of megaloblastic anemia frequently includes assessment of patient cobalamin and folate status. Current total serum cobalamin measurements are performed in the clinical laboratory with competitive binding luminescence assays, whose results may not always accurately ...
McTeer Jennifer - - 2013
Abstract This study assessed the bioavailability, toxicity and transfer of silver nanoparticles (AgNPs) in comparison with AgNO3 in two model food chain organisms; the alga Chlamydomonas reinhardtii and the grazing crustacean Daphnia magna. The effects of phosphate, a potential Ag+ binding ligand and a determinant of phytoplankton productivity, were evaluated. ...
Yousif Uqba N - - 2013
An association has been demonstrated between haemorrhoids and joint hypermobility. Reasons for this are discussed. Many performing artists are hypermobile and the extra-articular features of joint hypermobility should not be forgotten or underestimated as a potential constraint upon performance.
Vähäkangas Jarkko - - 2013
Nuclear magnetic resonance (NMR) data for graphenes are mainly lacking in the literature. We provide quantitative first-principles quantum-chemical calculations of NMR chemical shifts and shielding anisotropies as well as spin-spin couplings and anisotropies for increasingly large, hexagon-like fragments of graphene, hydrogenated graphene (graphane) and fluorinated graphene (fluorographene). Due to the ...
Cernusak Lucas A - - 2013
Leaf water becomes enriched in the heavy isotope (18) O through the process of transpiration. The leaf water (18) O signal is recorded in plant organic material (Barbour 2007), in atmospheric CO(2) via the activity of carbonic anhydrase (Farquhar et al. 1993), and in atmospheric O(2) through photosynthetic O(2) evolution ...
Schutting Susanne - - 2013
New indicators for optical CO2 sensors are synthesized in two steps from the commercially available diketo-pyrrolo-pyrrole (DPP) pigments Irgazin Ruby and Irgazin Scarlet. After introduction of bis(2-ethylhexyl) sulfonamide groups via a simple two-step synthesis the pigments are rendered highly soluble in organic solvents and in polymers and show pH-dependent absorption ...
Varni James W - - 2013
OBJECTIVES: In order to compare multidimensional fatigue research findings across age and gender subpopulations, it is important to demonstrate measurement invariance, that is, that the items from an instrument have equivalent meaning across the groups studied. This study examined the factorial invariance of the 18-item PedsQL™ Multidimensional Fatigue Scale items ...
Nassiri Farshad - - 2013
The pituitary is the master endocrine gland of the body. It undergoes many changes after birth, and these changes may be mediated by the differentiation of pituitary stem cells. Stem cells in any tissue source must display (1) pluripotent capacity, (2) capacity for indefinite self-renewal, and (3) a lack of ...
Grüebler Martin U - - 2013
The microclimate of potential roost-sites is likely to be a crucial determinant in the optimal roost-site selection of endotherms, in particular during the winter season of temperate zones. Available roost-sites for birds and mammals in European high trunk orchards are mainly tree cavities, wood stacks and artificial nest boxes. However, ...
Xu Kehua - - 2013
A highly selective and sensitive near-infrared (NIR) fluorescence probe (Cy-NO(2)) for imaging nitroreductase was developed and was successfully applied to investigating the relationship between epithelial-mesenchymal transitions (EMTs) in tumour progression and intracellular hypoxic level.
Basu Dipannita - - 2013
The human dopamine D2L receptor has significant implications in neurological and neuropsychiatric disorders such as Parkinson's disease and schizophrenia. Detailed structural knowledge of this receptor is limited due to its highly hydrophobic nature, which leads to protein aggregation and host toxicity when expressed in cellular systems. The newly emerging field ...
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