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Symens Nathalie - - 2013
In cationic carrier-mediated gene delivery, the disproportional relationship between the quantity of delivered DNA and the amount of encoded protein produced is a well-known phenomenon. The numerous intracellular barriers which need to be overcome by pDNA to reach the nucleoplasm play a major role in it. In contrast to what ...
Verma Priyanka - - 2013
A case-control study was conducted to estimate the association of cartilage oligomeric matrix protein (COMP) with knee osteoarthritis (OA) and to examine the potential utility of COMP as a diagnostic and prognostic biomarker in early knee OA. The COMP levels were estimated in the blood sera of 150 subjects belonging ...
Nakata Kouki - - 2013
On the basis of the Schwinger-Keldysh formalism, we have closely investigated the temperature dependence of quantum spin pumping generated using electron spin resonance. We have clarified that three-magnon splittings excite non-zero modes of magnons and characterize the temperature dependence of quantum spin pumping generated using electron spin resonance.
Kosinski M - - 2013
ObjectiveFatigue in systemic lupus erythematosus (SLE) is burdensome and must be assessed using validated scales. Although the psychometric properties of the Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-Fatigue) scale in SLE have been evaluated previously, its content validity in this disease remains to be evaluated. The study objective was, therefore, ...
Weng Zhe - - 2013
Maximized energy density: Controlled electrochemical charge injection (ECI) can be used for maximizing the energy density of supercapacitors (SCs). The electrode potential is tuned by the surface chemical structure of the electrode material to increase both the working voltage and the specific capacity of the SCs. As a result, the ...
Lan Cheng-Che E CC Department of Dermatology, Kaohsiung Medical University Hospital, Kaohsiung, - - 2013
Impaired wound healing frequently occurs in patients with diabetes. Interleukin (IL)-8 production by keratinocyte is responsible for recruiting neutrophils during healing. Intense inflammation is associated with diabetic wounds, while reduction of neutrophil infiltration is associated with enhanced healing. We hypothesized that increased neutrophil recruitment by keratinocytes may contribute to the ...
Handayani I P - - 2013
Time resolved optical spectroscopy is used to elucidate the dynamics of photodoped spin-aligned carriers in the presence of an underlying magnetic lattice in the multiferroic compound TbMnO(3). The transient responses while probing d-d intersite transitions show marked differences along different crystallographic directions, which are discussed in terms of the interplay ...
Rumm R - - 2013
This article analyses the impact of a potential deregulation Germany's pharmacy market by allowing foreign ownership of pharmacies and removing the limit of the number pharmacies that can be owned by a pharmacist. Based on a mathematical model and empirical values of foreign countries, scenarios for the German market are ...
Cheyne Andrew D - - 2013
The Institute of Medicine has warned of the harm of food marketing to children from television to new media channels such as the Internet. The authors identified and analyzed the techniques used to engage children on websites from cereal companies-the third largest food marketer to children. The authors found that ...
Li Baoxin B Department of Physiology and Pharmacology, Oregon Health & Science University, Portland, OR 97239, - - 2013
Although leptin is known to increase sympathetic nerve activity (SNA), we tested the hypothesis that leptin also enhances baroreflex control of SNA and heart rate (HR). Using α-chloralose anesthetized male rats, mean arterial pressure (MAP), HR, lumbar SNA (LSNA), splanchnic SNA (SSNA), and renal SNA (RSNA) were recorded before and ...
Meheretu Yonas - - 2013
Abstract More than 500 small mammals were trapped at 3 localities in northern Ethiopia to investigate Bartonella infection prevalence and the genetic diversity of the Bartonella spp. We extracted total DNA from liver samples and performed PCR using the primers 1400F and 2300R targeting 852 bp of the Bartonella RNA polymerase ...
Wu Wenjie - - 2013
A comprehensive understanding of the pathology of spinal cord injury (SCI) in non-human primates may facilitate greatly the development of new strategies to promote recovery in humans with SCI. However, relatively few studies have been conducted to systemically examine pathological changes in the monkey, a non-human primate, following SCI. Here ...
Egi Masahiro - - 2013
V for resolution: A new oxovanadium catalyst (V-MPS; see scheme) immobilized in the pores of mesoporous silica has been developed. The combined use of V-MPS and lipases achieved the dynamic kinetic resolution of a wide range of racemic alcohols (1 or 2) to produce optically active esters 3 in high ...
Bentayeb K - - 2013
Direct analysis in real time coupled to time-of-flight mass spectrometry (DART/TOF-MS) was used to detect the non-visible set-off of photoinitiators on the food contact surface of three different packages. The samples were intentionally under-cured to provoke set-off. Twelve commercially available photoinitiators were included in the ink formulations including α-amino-, morpholino, ...
Gráczer Eva - - 2013
To identify the rate limiting step(s) of 3-isopropylmalate dehydrogenase (IPMDH) catalysed reaction, time courses of NADH production were followed by stopped flow (SF) and quenched flow (QF). The steady state k(cat) and K(m) values did not vary between 0.1 and 20 µM enzyme concentrations. A burst phase of the NADH ...
Shang Ya Fang - - 2013
Three new chalcones, 3,2'-dihydroxy-4,3'-dimethoxychalcone-4'-glucoside (1), 4'-O-(2'''-O-caffeoyl)2',3',3,4-tetrahydroxychalcone (2), and 2',4',3-trihydroxy-3',4-dimethoxychalcone (3), along with five known phenolics, were isolated from Coreopsis lanceolata flowers. The structures of the new compounds were elucidated by extensive spectroscopic methods including NMR and MS. The three new chalcones showed a good in vitro HepG2 cell protecting effect ...
Altenhöner T - - 2013
Individual health behaviour counts as an important factor for health status. A healthier lifestyle substantially contributes to better health. People burdened with lower health and with lower socio-economic status could benefit notably. So far it is not known exhaustively to what extent education and social status contribute to changes in ...
Khan R A - - 2013
BACKGROUND: Cotton bollworm, Helicoverpa armigera hub. is a serious and cosmopolitan pest of many economic crops. Its control has not been adequate due to its resistance to many groups of insecticides. Toxicity of cantharidin on armyworm and diamondback moth has already been reported. However, its toxicity on H. armigera has ...
Chen Liang - - 2013
Highly porous hosting materials with conducting (favorable to electron transfer) and magnetic (favorable to product separation) bicontinuous networks should possess great potentials for immobilization of various enzymes in the field of biocatalytic engineering, but the synthesis of such materials is still a great challenge. Herein, bifunctional graphene/γ-Fe(2) O(3) hybrid aerogels ...
Yang Xu - - 2013
Although mechanical loading is known to influence trabecular bone adaptation, the role of specific loading parameters requires further investigation. Previous studies demonstrated that the number of loading cycles and loading duration modulate the adaptive response of trabecular bone in a rabbit model of applied loading. In the current study, we ...
Lo Regina Cheuk-Lam - - 2013
BACKGROUND AND AIMS: Complications after liver transplantation are major factors that determine the prognosis of patients. In this study, we aimed at investigating an important though less frequently occurring complication, post-transplant lymphoproliferative disorders (PTLD), in a single institution after liver transplantation. METHODS: 15 cases with a diagnosis of PTLD in ...
Calabrese Edward J - - 2013
This paper provides a detailed historical assessment of the origin and developmental progress of the concept of wound healing and its attempted acceleration from its start in the beginning of the 20th century to approximately 1960. Emphasis is placed on the development of cell culture in the assessment of wound ...
Gogoi Nayanmoni - - 2013
Heptacoordinated nickel(II) complexes characterized by substantial Ising-type single-ion anisotropy have been involved in the construction of two pentanuclear [Ni(3)W(2)] compounds by association with [W(CN)(8)](3-). For one of them, slow relaxation of magnetization was observed to occur concomitantly with antiferromagnetic ordering.
Gould Harley N HN National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, - - 2013
Turner Syndrome (TS) is due to X chromosome monosomy and affects ~1 per 2500 females at birth. The major features are short stature and primary ovarian failure. Short stature and monosomy for a maternal X chromosome have been implicated in impaired functionality in adult life; however, data on adult outcomes ...
Xu Boqun - - 2013
ABSTRACT: BACKGROUND: We found previously that the expression of SET gene was up-regulated in polycystic ovaries. Evidences suggested that SET protein was essential for regulating both the promoter activity of CYP17A1 and the biological activity of P450c17. In this study, we explored whether SET regulated androgen production in preantral follicles. ...
Vastani Nisha - - 2013
OBJECTIVES: The conformational state of voltage-gated sodium channels is an important determinant for the efficacy of both local anesthesia and electrical neuromodulation techniques. This study investigated the role of subthreshold preconditioning ramp currents on axonal nerve excitability parameters in the presence of sodium channel blockers in myelinated A and unmyelinated ...
Cook Carrie L - - 2013
Research about the attitudes and beliefs of correctional officers has historically been conducted in prison facilities while ignoring jail settings. This study contributes to our understanding of correctional officers by examining the perceptions of those who work in jails, specifically measuring professional orientations about counseling roles, punitiveness, corruption of authority ...
Zhao Xiao-Yun - - 2013
Melamine was employed as a pseudo template to prepare a molecularly imprinted polymer monolithic column which presents the ability of selective recognition to Triamterene, whose structure was similar to that of Melamine. Methacrylic acid and ethylene glycol dimethacrylate were applied as functional monomer and cross linker respectively during the in-situ ...
Goldstein Bradley J - - 2013
BACKGROUND: The olfactory epithelium is a self-renewing tissue, able to produce new neurons as needed from stem and progenitor cells in its basal layers. In addition, there exists a mesenchymal-like stem cell (MSC) located within the underlying lamina propria. Little is known about the function of this nasal MSC, or ...
Peng Jin-Bao - - 2013
A novel cascade reaction involving oxidative dearomatization/semipinacol rearrangement of indol-2-yl cyclobutanols is explored with N-sulfonyloxaziridine (Davis oxaziridines) as oxidant, generating various 2-spiroquaternary 3-oxindoles in modest to good yields. This method might be useful in the synthesis of indole-based alkaloids bearing 2-spiroquaternary carbon centers. PTS=p-toluenesulfonic acid monohydrate.
Granö Niklas - - 2013
Background: Little is known about how symptoms are changed in adolescents who receive treatment in an early detection and intervention service. Aims: The aims of the present research were to study change in depression, anxiety and hopelessness symptoms in a sample of help-seeking adolescents who participated in a community- and ...
Seth Akhil K - - 2013
Bacterial biofilms, a critical chronic wound mediator, remain difficult to treat. Energy-based devices may potentially improve healing, but with no evidence of efficacy against biofilms. This study evaluates noncontact, low-frequency ultrasound (NLFU) in the treatment of biofilm-infected wounds. Six-millimeter dermal punch wounds in rabbit ears were inoculated with 10(7) colony-forming ...
Sepsas Evangelos E Department of Thoracic Surgery, Sotiria General Hospital for Chest Diseases, Athens, - - 2013
Patients undergoing thoracotomy were studied to compare the effects of cryoanalgesia, combined with intravenous patient-controlled analgesia (IVPCA), against IVPCA alone during the four days following surgery. Fifty patients were randomized into two groups: an IVPCA group (n = 25) and an IVPCA-cryo group (n = 25). Subjective pain intensity was ...
Lewandowski Wiktor - - 2013
Hybrid structures made of metal nanoparticles with liquid crystalline coating attract considerable attention due to their conspicuous self-assembly and potential synergistic properties. Here we report on a new structural parameter that can be used to control the formation of hybrid gold nanoparticles superlattice. Series of Au nanoclusters covered with mixed ...
Rodriguez Jesse M JM Department of Computer Science, Stanford University, Stanford, California 94305, USA. - - 2013
Inferring the ancestral origin of chromosomal segments in admixed individuals is key for genetic applications, ranging from analyzing population demographics and history, to mapping disease genes. Previous methods addressed ancestry inference by using either weak models of linkage disequilibrium, or large models that make explicit use of ancestral haplotypes. In ...
Kaufman Sydney H - - 2013
In the present study, we investigate the spectroscopy and photochemical behavior of chromate ester cluster ions in vacuo in the visible and near UV. Chromate ester cluster ions Nan[CrO3(OCH3)]n+1- (n = 1, 2) are generated by electrospray ionization of sodium dichromate in water and methanol. Upon irradiation with photon energies ...
Wang Shanshan - - 2013
Enhancer of zeste homolog 2 (EZH2) is a mammalian histone methyltransferase (HMT) that contributes to the epigenetic silencing of target genes that regulates cancer cells growth and survival. EZH2 is overexpressed in hepatocellular carcinoma (HCC) with clinical significance that remains obscure. Sorafenib, a multikinase inhibitor, has been used as a ...
Heinen Jennifer - - 2013
The synthesis of a series of co-oligomer amphiphiles by RAFT and their self-assembly behaviour in water is described. These novel amphiphiles, comprised of styrene, butyl acrylate and alkyl hydrophobes together with ionizable acrylic acid and nonionic hydroxyethylacrylate hydrophilic moieties and with total degrees of polymerization from 5 to 17, are ...
Day K M - - 2013
AIMS: To evaluate two chromogenic media, Brilliance CRE and chromID CARBA, with stool samples referred to the Public Health Laboratories Division of the National Institute of Health in Islamabad, and assess the prevalence of carbapenemase-producing Enterobacteriaceae (CPE) in this population. METHODS AND RESULTS: One hundred and fifty two stool samples ...
Jacobs Elizabeth T ET University of Arizona Cancer Center, University of Arizona, Tucson, AZ, - - 2013
Vitamin D is a well-studied agent for cancer chemoprevention and treatment. Its chief circulating metabolite, 25-hydroxyvitamin D, is converted into the active hormone 1,25-dihydroxyvitamin D (1,25D) by the cytochrome P450 enzyme CYP27B1 in kidney and other tissues. 1,25D is then deactivated by CYP24A1 and ultimately catabolized. Colorectal carcinoma cells express ...
Head Stuart J - - 2013
OBJECTIVES: Risk prediction in adult patients undergoing cardiac surgery remains inaccurate and should be further improved. Therefore, we aimed to identify risk factors that are predictive of mortality, stroke, renal failure and/or length of stay after adult cardiac surgery in contemporary practice. METHODS: We searched the Medline database for English-language ...
Bredtmann Timm - - 2013
Pericyclic reactions with energies E well above the potential energy barrier B (case E>B) proceed with quantum nuclear flux densities 〈j〉 which are essentially proportional to the nuclear densities ρ in the femtosecond time domain. This corresponds to the definition of classical (cl) mechanics, j(cl) =υ(cl) ρ(cl) , with almost ...
Nambiar Prashant R - - 2013
A factor limiting widespread use of the transgenic rasH2 mouse model for carcinogenicity testing of pharmaceuticals is the paucity of published data on actual drug candidates in rasH2 mice. This report addresses this gap by highlighting rasH2 mouse study data for 10 pharmaceutical candidates. These results were compared with findings ...
Wang Luo-Yi - - 2013
(M)-Bicelaphanol A (1) and (P)-bicelaphanol A (2), two unprecedented dimeric trinorditerpenes existing as atropisomers, together with their monomer celaphanol A (3), were isolated from the root bark of Celastrus orbiculatus. The structures and absolute configurations of 1 and 2 were determined by spectroscopic and single-crystal X-ray diffraction analyses. Compound 1 ...
Liu Jinman - - 2013
In fungi and metazoans, extracellular signals are often perceived by G protein-coupled receptors (GPCRs) and transduced through heterotrimeric G protein complexes to downstream targets. Plant heterotrimeric G proteins are also involved in diverse biological processes, but little is known about their upstream receptors. Moreover, the presence of bona fide GPCRs ...
Saha Sumit - - 2013
The reaction of Ru(5)(CO)(15)(μ(5)-C) with Ni(COD)(2) in acetonitrile at 80 °C affords the bimetallic octahedral ruthenium-nickel cluster complex Ru(5)Ni(NCMe)(CO)(15)(μ(6)-C), 3. The acetonitrile ligand in 3 can be replaced by CO and NH(3) to yield Ru(5)Ni(CO)(16)(μ(6)-C), 4, and Ru(5)Ni(NH(3))(CO)(15)(μ(6)-C), 5, respectively. Photolysis of compound 3 in benzene and toluene solvent yielded ...
Tang Dai-Ming - - 2013
Mechanical properties and fracture behaviors of multiwalled WS2 nanotubes produced by large scale fluidized bed method were investigated under uniaxial tension using in situ transmission electron microscopy probing; these were directly correlated to the nanotube atomic structures. The tubes with the average outer diameter ~ 40 nm sustained tensile force ...
Fukuda Katsutoshi - - 2013
The metallization behavior of molecularly thin RuO(2) nanosheets obtained from complete delamination of layered ruthenates was studied. Interestingly, the RuO(2) nanosheets in a monolayer state topotactically transformed into a single layer of Ru atoms, i.e., ruthenium metal nanosheets, which can be regarded as a new family of nanosized metals.
Marabita Francesco - - 2013
The proper identification of differentially methylated CpGs is central in most epigenetic studies. The Illumina HumanMethylation450 BeadChip is widely used to quantify DNA methylation; nevertheless, the design of an appropriate analysis pipeline faces severe challenges due to the convolution of biological and technical variability and the presence of a signal ...
Cage Tene A - - 2013
Recurrent glioblastoma (GBM) can occur locally or at distant sites within the brain. Though MRI is the standard imaging modality for primary and recurrent GBM, the full extent of diffuse lesions may not be appreciated on MRI alone. Glioblastomas with ependymal and/or subependymal spread are examples of diffuse infiltrative tumors ...
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