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Wright Louise B - - 2013
Harnessing the properties of biomolecules, such as peptides, adsorbed on inorganic surfaces is of interest to many cross-disciplinary areas of science, ranging from biomineralisation to nanomedicine. Key to advancing research in this area is determination of the peptide conformation(s) in its adsorbed state, at the aqueous interface. Molecular simulation is ...
Swenson-Fields Katherine I KI Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, Kansas 66160, - - 2013
Renal M2-like macrophages have critical roles in tissue repair, stimulating tubule cell proliferation and, if they remain, fibrosis. M2-like macrophages have also been implicated in promoting cyst expansion in mouse models of autosomal dominant polycystic kidney disease (ADPKD). While renal macrophages have been documented in human ADPKD, there are no ...
Mecca Tommaso - - 2013
Water soluble amphiphilic calix[8]arenes have been found to form pH-responsive and reversible supramolecular hydrogels at sub-millimolar concentration. Depending on their upper rim functionalization, pH variations trigger hydrogelation under basic or acidic conditions. Studies on self-organization processes by atomic force microscopy (AFM) measurements on differently charged surfaces are reported.
Scheid Taína - - 2013
Neuropathic pain is a very common dysfunction caused by several types of nerve injury. This condition leads to a variety of pathological changes in central nervous system regions related to pain transmission. It has been demonstrated that nociception is modulated by reactive oxidative species and treatments with antioxidant compounds produce ...
Xu Kehua - - 2013
A highly selective and sensitive near-infrared (NIR) fluorescence probe (Cy-NO(2)) for imaging nitroreductase was developed and was successfully applied to investigating the relationship between epithelial-mesenchymal transitions (EMTs) in tumour progression and intracellular hypoxic level.
Basu Dipannita - - 2013
The human dopamine D2L receptor has significant implications in neurological and neuropsychiatric disorders such as Parkinson's disease and schizophrenia. Detailed structural knowledge of this receptor is limited due to its highly hydrophobic nature, which leads to protein aggregation and host toxicity when expressed in cellular systems. The newly emerging field ...
Tabart Jeremy - - 2013
Rearing pests or parasites of very small size in the absence of their living host is a challenge for behavioural, physiological and pathological studies. For feeding Varroa destructor, an ectoparasitic mite of Apis mellifera, a confinement space with a membrane separating the nutritive solution and the space was designed. The ...
Keene Tony D - - 2013
Dynamically porous metal-organic frameworks (MOFs) with a chiral quartz-based structure have been synthesized from the multidentate ligand 2,2'-dihydroxybiphenyl-4,4'-dicarboxylate (H(2)diol). Compounds [Ni(ii)(H(2)diol)(S)(2)]·xS (where S = DMF or DEF) show marked changes in 77 K N(2) uptake between partially desolvated [Ni(ii)(H(2)diol)(S)(2)] (only the pore solvent is removed) and fully desolvated [Ni(ii)(H(2)diol)] forms. ...
Delgado-Plasencia Luciano - - 2013
PURPOSES: Methylenetetrahydrofolate reductase (MTHFR) plays a key role in folate metabolism, and folate is implicated in carcinogenesis by its role in DNA methylation, repair, and synthesis. We analyzed the impact of MTHFR C677T polymorphism in colorectal cancer in a region of the Tenerife Island whose population has a history of ...
Pillay Janesh - - 2013
Neutrophils are essential effector cells in the host defense against invading pathogens. Recently, novel neutrophil functions have emerged in addition to their classical anti-microbial role. One of these functions is the suppression of T cell responses. In this respect, neutrophils share similarities with granulocytic myeloid-derived suppressor cells (G-MDSCs). In this ...
Frauenfelder F - - 2013
ACCESSIBLE SUMMARY: The use of a standardized nursing language enhances nursing quality. The Nursing Interventions Classification (NIC) considers any treatment by nurses that improve patient outcomes. The present study identifies nursing interventions in journal articles on adult psychiatric inpatient nursing care. These interventions are compared with the NIC entries to ...
Lu Lingli - - 2013
Sedum alfredii is one of a few species known to hyperaccumulate zinc (Zn) and cadmium (Cd). Xylem transport and phloem remobilization of Zn in hyperaccumulating (HP) and nonhyperaccumulating (NHP) populations of S. alfredii were compared. Micro-X-ray fluorescence (μ-XRF) images of Zn in the roots of the two S. alfredii populations suggested an ...
Tsao Sean W - - 2013
Age-related macular degeneration (AMD) is a leading cause of blindness worldwide for which preventative therapies are few. Evidence suggesting shared common risk factors and mirrored pathophysiology between cardiovascular disease and AMD led to the hypothesis that hydroxymethylglutaryl-CoA reductase inhibitors (statins) could be helpful in preventing AMD. For over a decade, ...
Terashima Yoshitaka - - 2013
Boron-modified pyrrole-based anion receptors (catechol-boron and diphenylboron dipyrrolyldiketone derivatives) formed planar receptor-anion complexes, leading to charge-by-charge assemblies with planar cations, as in the corresponding difluoroboron derivative.
Neophytou Andreas M - - 2013
Ambient particulate matter (PM) has been shown to have short- and long-term effects on cardiorespiratory mortality and morbidity. Most of the risk is associated with fine PM (PM(2.5)); however, recent evidence suggests that desert dust outbreaks are major contributors to coarse PM (PM(10-2.5)) and may be associated with adverse health ...
Serres Sébastien S Department of Oncology, CR-UK/MRC Gray Institute for Radiation Oncology and Biology, University of Oxford, Oxford, - - 2013
Interferon-β (IFN-β) drugs are considered to derive their beneficial effects on multiple sclerosis (MS) progression via their antiinflammatory properties, but the precise mechanism of action remains unclear. Here, we sought to discover how IFN-β impacts on inflammation-associated aggravation of MS-like lesions in rat. Animals with dormant focal experimental allergic encephalomyelitis ...
Gómez-Orte Eva - - 2013
LTR retrotransposons are major components of plant genomes playing important roles in the evolution of their host genomes, for example, generating new genes or providing new promoters to existing genes. The Grande family of retrotransposons is present in Zea species and is characterized by an unusually long internal region due ...
Hou Wai Kai - - 2013
This study examined prospective reciprocity between psychological distress and subjective well-being and the role of change in psychosocial resources in the reciprocity in the year following cancer diagnosis. Psychological distress (Hospital Anxiety and Depression Scale), subjective well-being (Chinese Affect Scale and Satisfaction with Life Scale), and psychosocial resources of 180 ...
Wang Min - - 2013
Enantioselective cyclization of α-isocyano esters with azodicarboxylates catalyzed by Fe(II)-N,N'-dioxide complexes has been developed. Under mild conditions, a variety of 1,2,4-triazoline derivatives was obtained in high yields and enantioselectivities.
Fortress Ashley M AM Department of Psychology, University of Wisconsin-Milwaukee, Milwaukee, WI 53211, - - 2013
The mammalian target of rapamycin (mTOR) signaling pathway is an important regulator of protein synthesis and is essential for various forms of hippocampal memory. Here, we asked whether the enhancement of object recognition memory consolidation produced by dorsal hippocampal infusion of 17β-estradiol (E(2)) is dependent on mTOR signaling in the ...
Lopez Carlos F - - 2013
Mathematical equations are fundamental to modeling biological networks, but as networks get large and revisions frequent, it becomes difficult to manage equations directly or to combine previously developed models. Multiple simultaneous efforts to create graphical standards, rule-based languages, and integrated software workbenches aim to simplify biological modeling but none fully ...
Hou Weijian - - 2013
Abstract Conclusions: The most frequently affected sites of cranial complications of endoscopic sinus surgery (ESS) are the boundary between the anterior and posterior ethmoid roof, the frontal recess, and the cribriform plate. Being aware of cranial complications in time and provision of appropriate treatment may minimize the serious consequences. Objectives: ...
Xu Chao - - 2013
Complexation of UO(2)(2+) with dipicolinic acid (DPA) has been investigated in 0.1 M NaClO(4). The stability constants (log β(1) and log β(2)) for two successive complexes, UO(2)L and UO(2)L(2)(2-) where L(2-) stands for the deprotonated dipicolinate anion, were determined to be 10.7 ± 0.1 and 16.3 ± 0.1 by spectrophotometry. ...
Buettner Manuela - - 2013
The repeated application of antigens results in the induction of tolerance. Lymph nodes are responsible for this reaction by producing suppressor cells. Using an in vivo transplantation model we showed recently that stromal cells from different lymph nodes induce different cell populations for suppression, which all produce a tolerogenic phenotype. ...
Kobayashi Hirokazu - - 2013
The molecular orientation and dynamics of di-t-butylnitroxide (DTBN) and 4-oxo-2,2,6,6-tetramethyl-1-piperidinyl-1-oxyl (TEMPONE) radicals in the organic 1-D nanochannels of tris(o-phenylenedioxy)cyclotriphosphazene (TPP) were investigated by examining inclusion compounds (ICs) diluted by the co-inclusion of non-radicals using electron spin resonance (ESR). Spectral simulation showed that the axial rotation of DTBN or TEMPONE molecules ...
Conzuelo Felipe - - 2013
A novel strategy for the construction of disposable amperometric affinity biosensors is described in this work. The approach uses a recombinant bacterial Penicillin Binding Protein (PBP) tagged by an N-terminal hexahistidine tail which was immobilized onto Co2+-tetradentate nitrilotriacetic acid (NTA) modified screen-printed carbon electrodes (SPCEs). The biosensor was employed for ...
Forge Andrew A Centre for Auditory Research, UCL Ear Institute, London WC1X 8EE, UK. - - 2013
A role for connexin (Cx)30 in epithelial repair following injury was examined in the organ of Corti, the sensory epithelium of the cochlea. In this tissue, lesions caused by loss of the sensory hair cells are closed by the supporting cells that surround each one. Gap junctions in which Cx30 ...
Couturier Marc Roger - - 2013
BACKGROUND: Respiratory pathogens are a leading cause of hospital admission and traditional detection methods are time consuming and insensitive. Multiplex molecular detection methods have recently been investigated in hope of replacing these traditional techniques with rapid panel-based testing. OBJECTIVES: This study evaluated the FilmArray® Respiratory Panel ([FARP], Idaho Technology Inc., ...
Niyonkuru Christian - - 2013
Over the last decade, biomarker research has identified potential biomarkers for the diagnosis, prognosis, and management of traumatic brain injury (TBI). Several cerebrospinal fluid (CSF) and serum biomarkers have shown promise in predicting long-term outcome after severe TBI. Despite this increased focus on identifying biomarkers for outcome prognostication following a ...
Luu H N HN Dan L Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030, - - 2013
Although the independent effects of smoking status and HAART are reported as lower risks against KS, their combined effects have not been explored. We examined whether there is an interaction between smoking status and HAART use on the risk of KS development in an on-going US cohort of HIV-infected men. ...
Lee Grace M GM Division of Hematology, Duke University Medical Center, Durham, NC 27710, - - 2013
Protamine is routinely used to reverse heparin anticoagulation during cardiopulmonary bypass (CPB). Heparin interacts with protamine to form ultralarge complexes that are immunogenic in mice. We hypothesized that patients exposed to protamine and heparin during CPB will develop antibodies (Abs) to protamine/heparin (PRT/H) complexes that are capable of platelet activation. ...
Cancela Jose M - - 2013
The aim of this study was to revise and organize according to recall time based criteria, questionnaires created and validated to assess the level of physical activity in children and adolescents, with the intention of enabling their proper understanding and subsequent use by nurses and health care professionals. In order ...
Hall Bradford - - 2013
ABSTRACT: BACKGROUND: The sixth leading class of cancer worldwide is head and neck cancer, which typically arise within the squamous epithelium of the oral mucosa. Human head and neck squamous cell carcinoma (HNSCC) is known to be difficult to treat and has only a 50% five-year survival rate. With HNSCC, ...
Spiegel David - - 2013
In this review, the role of hypnosis and related psychotherapeutic techniques are discussed in relation to the anxiety disorders. In particular, anxiety is addressed as a special form of mind/body problem involving reverberating interaction between mental and physical distress. The history of hypnosis as a therapeutic discipline is reviewed, after ...
Bakhireva Ludmila N LN Department of Pharmacy Practice and Administrative Sciences, University of New Mexico Health Sciences Center, Albuquerque, NM, USA. - - 2013
Accurate confirmation of prenatal alcohol exposure (PAE) is required as a diagnostic criterion for the majority of children adversely affected by PAE who do not manifest the physical features associated with fetal alcohol syndrome. A number of ethanol biomarkers have been used to assess PAE, often with suboptimal results. The ...
Göriş Songül - - 2013
Abstract Objectives: This experimental study was conducted to determine the effects of training on inhaler technique and quality of life in patients with chronic obstructive pulmonary disease (COPD). Methods: Among the patients who applied at the outpatient clinic of chest diseases between March 2009 and May 2010, a total of ...
Godderis Rebecca - - 2013
The concept of evidence has become central in Western healthcare systems; however, few investigations have studied how the shift toward specific definitions of evidence actually occurred in practice. This paper examines a historical case in psychiatry where the debate about how to define evidence was of central importance to nosological ...
Holm Lars L Institute of Sports Medicine, Department of Orthopedic Surgery M81, Bispebjerg Hospital, and Center for Healthy Aging, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. - - 2013
A method to determine the rate of protein breakdown in individual proteins was developed and tested in rats and confirmed in humans, using administration of deuterium oxide and incorporation of the deuterium into alanine that was subsequently incorporated into body proteins. Measurement of the fractional breakdown rate of proteins was ...
Assali Mohyeddin - - 2013
Herein, we describe the first report on a new class of disk-shaped and quite monodisperse water soluble nanomaterials that we named glyconanosomes (GNS). GNSs were obtained by sliding out the cylindrical structures formed upon self-organization and photo-polymerization of glycolipid 1 on single wall carbon nanotubes (SWCNTs) sidewalls. GNSs present a ...
Overstall Antony M - - 2013
Summary Bayesian inference is considered for statistical models that depend on the evaluation of a computationally expensive computer code or simulator. For such situations, the number of evaluations of the likelihood function, and hence of the unnormalized posterior probability density function, is determined by the available computational resource and may ...
Lietzau Markus - - 2013
Abstract Objective: This retrospective clinical investigation intends to examine the effectiveness of an Er:YAG laser used in conjunction with a dental operation microscope for apicoectomy, in comparison with the traditional surgical procedure. Background data: The Er-YAG laser has shown great potential in application to periapical surgery; however, clinical data are ...
Mendes Cristiani Cortez CC Unidade de Pesquisa em Genética e Biologia Molecular, Faculdade de Medicina de São José do Rio Preto (FAMERP), São José do Rio Preto, São Paulo, - - 2013
Down syndrome (DS) results from the presence and expression of three copies of the genes located on chromosome 21. Studies have shown that, in addition to overexpression of the Cystathionine β-synthase (CBS) gene, polymorphisms in genes involved in folate/homocysteine (Hcy) metabolism may also influence the concentrations of metabolites of this ...
Xu He - - 2013
Biofilms are complex communities of microorganisms living together at an interface. Because biofilms are often associated with contamination and infection, it is critical to understand how bacterial cells adhere to surfaces in the early stages of biofilm formation. Even harmless commensal Escherichia coli naturally forms biofilms in the human digestive ...
Lee Sangmoon - - 2013
Objectives. Pituitary adenomas often cause deficits in visual acuity (VA) and visual field (VF) due to compression of the optic chiasm. This study is to identify factors most likely to predict the prognosis of VA and VF after transsphenoidal pituitary adenectomy. Materials and methods. Clinical records of patients who underwent ...
Jaworski Deborah C - - 2013
Abstract Animal models for Ehrlichia chaffeensis have been unsuccessful in recapitulating the natural disease cycle. We have developed an animal model for tick feeding and transmission using white-tailed deer (Odocoileus virgianus), the intracellular bacterium (Ehrlichia chaffeensis), and the lone star tick vector (Amblyomma americanum). Here, we report the acquisition and ...
Yan Shuling - - 2013
During Drosophila embryogenesis the first epithelium with defined cortical compartments is established during cellularization. Actin polymerization is required for the separation of lateral and basal domains as well as suppression of tubular extensions in the basal domain. The actin nucleator mediating this function is unknown. We found that the formin ...
Vlak Monique H M - - 2013
BACKGROUND AND PURPOSE: Three percent of the population has an unruptured intracranial aneurysm (UIA). We aimed to identify independent risk factors from lifestyle and medical history for the presence of UIAs and to investigate the combined effect of well-established risk factors. METHODS: We studied 206 patients with an UIA who ...
Khan Sadaf S School of Chemistry and Biochemistry, The University of Western Australia, Crawley, Western Australia, - - 2013
Breast milk composition can be affected by several factors, and it can exhibit short-term (weekly) variations. Investigating variations in breast milk composition is important to accurately estimate nutrient requirements of the infant. To investigate short-term changes in breast milk composition between left and right breasts, over a 3-week period within ...
Lin Sheng - - 2013
BACKGROUND: There is a high prevalence of Hepatitis B virus (HBV) infection in China. The aim of this article is to reveal the HBV prevalence and its outcome in southern China by analyzing the HBV serum markers and their relationship to HBV genotype. METHODS: HBV serum markers, HBV-DNA and Alanine ...
van Oostrom Hugo - - 2013
OBJECTIVE: To compare airway management using the v-gel supraglottic airway device (v-gel SGAD) to that using an endotracheal tube (ETT), with respect to practicability, leakage of volatile anaesthetics and upper airway discomfort in cats. STUDY DESIGN: Prospective, randomized clinical trial. ANIMALS: Twenty European Shorthair cats (9 males, 11 females), weighing ...
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