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Results 501 - 550 of 3060
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Zhang Deng-Feng - - 2013
The complement system plays multiple roles in host defense against infection and is supposed to confer genetic susceptibility to leprosy. We aimed to examine whether genetic variants of the Ficolin-2 (FCN2), Mannose-binding lectin (MBL2) and Complement factor H (CFH) genes, which are involved in activation and regulation of the complement ...
Fernie A R - - 2013
Metabolic fluxes and the capacity to modulate them are a crucial component of the ability of the plant cell to react to environmental perturbations. Our ability to quantify them and to attain information concerning the regulatory mechanisms which control them is therefore essential to understand and influence metabolic networks. For ...
Böttcher Svenja - - 2013
The aim of this research was to investigate the influence of a social-evaluative context on simple cognitive tasks. While another person present in the room evaluated photographs of beautiful women or landscapes by beauty/attractiveness, female participants had to perform a combination of digit-categorization and spatial-compatibility task. There, before every trial, ...
Agarwal Praveen Kumar - - 2013
Pyruvate decarboxylases (PDCs) are a class of enzymes which carry out the non-oxidative decarboxylation of pyruvate to acetaldehyde. These enzymes are also capable of carboligation reactions and can generate chiral intermediates of substantial pharmaceutical interest. Typically, the decarboxylation and carboligation processes are carried out using whole cell systems. However, fermentative ...
Avivi Irit - - 2013
Predictive value (PV) of surveillance fluorodeoxyglucose positron emission tomography (FDG-PET) in patients with diffuse large B-cell lymphoma (DLBCL) treated with chemotherapy-rituximab (R) versus chemotherapy only, remains unclear. The aim of the current study was to compare the performance of surveillance PET in DLBCL patients receiving CHOP (cyclophosphamide, hydroxydaunorubicin hydrochloride, vincristine ...
Bugey Aurélie - - 2013
Photoinitiators are used to promote the polymerization process during the curing of varnishes or inks on cartonboard packaging. Depending on storage conditions and shelf life, these substances are able to migrate through the packaging layer into the foodstuff. This type of contamination phenomenon is therefore becoming a critical issue in ...
Jentzsch Thorsten T Department of Orthopaedics, Balgrist University Hospital, Zurich, - - 2013
Reconstruction of the extensor mechanism after resection of the proximal tibia is challenging, and several methods are available. A medial gastrocnemius flap commonly is used, although it may be associated with an extensor lag. This problem also is encountered, although perhaps to a lesser extent, with other techniques for reconstruction ...
Tong Mingjie M Department of Otology and Laryngology, Harvard Medical School, Boston, MA 02115, - - 2013
Regeneration of synaptic connections between hair cells and spiral ganglion neurons would be required to restore hearing after neural loss. Here we demonstrate by immunohistochemistry the appearance of afferent-like cochlear synapses in vitro after co-culture of de-afferented organ of Corti with spiral ganglion neurons from newborn mice. The glutamatergic synaptic ...
Zeng L L Department of Oral Biology, College of Dentistry, University of Florida, Gainesville, FL 32610, - - 2013
Three genes predicted to encode the A, B and C domains of a sugar : phosphotransferase system (PTS) permease specific for galactose\(EII(Gal) ) were identified in the genomes of 35 of 57 recently sequenced isolates of Streptococcus mutans, the primary etiological agent of human dental caries. Mutants defective in the EII(Gal) complex ...
Igic Boris - - 2013
1 I. 1 II. 3 III. 5 IV. 8 V. 9 10 References 10 SUMMARY: A compound hypothesis positing that self-fertilization is an evolutionary dead end conflates two distinct claims: the transition from outcrossing to selfing is unidirectional; and the diversification rate, or the balance of the speciation and extinction ...
Kitazawa Soichiro - - 2013
It is becoming increasingly clear that proteins transiently populate high-energy excited states as a necessary requirement for function. Here, we demonstrate that rational mutation based on the characteristics of the structure and dynamics of proteins obtained from pressure experiments is a new strategy for amplifying particular fluctuations in proteins. We ...
Van Den Eeden Stephen K - - 2013
ABSTRACT: BACKGROUND: Studies of the impact of type 2 diabetes on the prevalence and incidence of lower urinary tract symptoms (LUTS) among men have provided divergent results. We sought to examine this issue using two large and diverse cohorts. METHODS: This study used questionnaire and clinical data from two large ...
Schnelldorfer Thomas - - 2013
BACKGROUND: Gallbladder wall calcifications, otherwise known as porcelain gallbladder, have received considerable attention due to its perceived association with gallbladder carcinoma. While the perception of a strong correlation persists, more recent reports raise conceivable doubts. STUDY DESIGN: A systematic literature search was conducted of human studies describing gallbladder wall calcification ...
Kuri Thomas - - 2013
Secondary infections with Streptococcus pneumoniae (SP) are frequently observed following influenza A virus (IAV) infection and have a substantial impact on global health. Despite this, the basis for the disease progression is incompletely understood. To investigate the effect of co-infection on human monocyte-derived dendritic cells (MDDCs) we analyzed the expression ...
Karussis Dimitrios - - 2013
It is widely accepted that the main common pathogenetic pathway in multiple sclerosis (MS) involves an immune-mediated cascade initiated in the peripheral immune system and targeting CNS myelin. Logically, therefore, the therapeutic approaches to the disease include modalities aiming at downregulation of the various immune elements that are involved in ...
Wang Connie J - - 2013
Although water is essential for life, its use for medicinal purposes is not universally accepted. We performed a comprehensive review of the literature to determine where the evolving state of knowledge lies regarding the benefits of water as a therapy for renal diseases. In the past two decades, water has ...
Liu Yang - - 2013
The objective of the current study was to investigate the expression pattern and clinicopathological significance of differentiated embryo-chondrocyte-expressed gene 1 (DEC1) in patients with non-small-cell lung cancer (NSCLC). In 118 archived NSCLC tissues, the positive rate of DEC1 was reduced in human lung cancer samples (36/118, 30.5 %) compared with adjacent ...
Opik Maarja - - 2013
We aimed to enhance understanding of the molecular diversity of arbuscular mycorrhizal fungi (AMF) by building a new global dataset targeting previously unstudied geographical areas. In total, we sampled 96 plant species from 25 sites that encompassed all continents except Antarctica. AMF in plant roots were detected by sequencing the ...
Torun Emel - - 2013
Abstract Aim: To evaluate the clinical and biochemical findings of the children and adolescents with vitamin D deficiency and insufficiency in order to determine the clinical and biochemical presentation differences between age groups. Methods: This retrospective study included a review of medical reports of 543 patients (aged between 1-17 years) ...
Marco Helena - - 2013
The survival after renal transplantation of patients with antineutrophil cytoplasmic antibody (ANCA)-associated to systemic vasculitis is as good as in other diseases, although most of the reports are based on small numbers of patients. Furthermore, it is not known whether comorbidities (cardiovascular [CV] disease and cancer) are more frequent than ...
Liu Xun - - 2013
Reducing sugar (RS) accumulation in cold-stored potato tubers, known as cold-induced sweetening (CIS), is a crucial factor causing unacceptable colour changes and acrylamide formation of fried products. The activity of vacuolar invertase (StvacINV1) is proved important for the CIS process, and invertase inhibitors are speculated to play roles in the ...
Malwal Satish R - - 2013
In order to understand precise biological roles of sulfur dioxide (SO(2)), reliable SO(2) donors, compounds that produce SO(2) under physiological conditions, are necessary. The design and development of 1-phenyl-benzosultine as an efficient SO(2) donor is reported. This compound undergoes cycloreversion to generate SO(2) upon dissolution in aqueous buffer at 37 ...
Byberg R - - 2013
The photocatalytic degradation of a series of six acid dyes (Direct Red 80, Direct Red 81, Direct Red 23, Direct Violet 51, Direct Yellow 27, and Direct Yellow 50) has been tested compared in terms of color removal, mineralization, and toxicity (Lactuca sativa L. test) after photocatalysis on immobilized titanium ...
Meyer Markus - - 2013
We sought to evaluate the safety and efficacy of N-acetylcysteine (NAC) on ischemia and reperfusion in a pig model focusing on cardio-renal protection. High doses of NAC may provide protection from contrast induced nephropathy (CIN). NAC has also been demonstrated to reduce myocardial infarction size and improve left ventricular function ...
Micale Rosanna T - - 2013
Birth and early life stages are critical periods characterized by severe alterations of the redox balance and by "physiological" genomic changes in lung cells, which may be responsible for cancer and other diseases in adulthood. Oxidative stress is a major mechanism accounting for the carcinogenicity of cigarette smoke (CS), which ...
Liu Yen-Liang - - 2013
Based on specific chemical reactions carried out at ambient temperature, an ultrasensitive and chemoselective measurement of both acyclic and cyclic ketone gases, such as acetone (a disease biomarker) and cyclohexanone (a signature chemical emanating from C-4 plastic explosives), in real time was efficiently achieved on QCM chips thin-coated with sensing ...
Samaranayake N R - - 2013
Background The primary goal of reducing medication errors is to eliminate those that reach the patient. Objective We aimed to study the pattern of interceptions to tackle medication errors along the medication use processes. Setting Tertiary care hospital in Hong Kong. Method The 'Swiss Cheese Model' was used to explain ...
Dhital Raghu Nath - - 2013
The strong inhibitor effect of aryl iodides on the quasi-homogenous gold-catalyzed oxidation reaction was described. Aryl iodides were adsorbed on the exposed surface of Au clusters, which affected the accessibility of the nanoclusters to the reacting species and acted as strong inhibitors in catalysis.
Dante Angelo - - 2013
Empirical studies and conceptual frameworks presented in the extant literature offer a static imagining of academic failure. Time-to-event analysis, which captures the dynamism of individual factors, as when they determine the failure to properly tailor timely strategies, impose longitudinal studies which are still lacking within the field. The aims of ...
Zanderigo Francesca F Department of Psychiatry and Behavioral Science, Stony Brook University, New York, New York 11794-8101, USA. - - 2013
Reference region (RR) approaches (RRAs) for positron emission tomography (PET) brain studies aim to obtain full quantification without arterial input function (IF) sampling, an invasive and costly procedure. Although they need a reliable RR and are only able to estimate the nondisplaceable binding potential (BPND), RRAs are widely used. If ...
Knights J J Department of Pharmaceutical Sciences, State University of New York, Buffalo, NY, - - 2013
We develop an information-theoretic method for gene-gene (GGI) and gene-environmental interactions (GEI) analysis of syndromes, defined as a phenotype vector comprising multiple quantitative traits (QTs). The K-way interaction information (KWII), an information-theoretic metric, was derived for multivariate normal distributed phenotype vectors. The utility of the method was challenged with three ...
Fukuda Izumi - - 2013
Untreated acromegaly is associated with a twofold to fourfold increased mortality risk compared to the population. Recently, new therapeutic modalities have been developed and may contribute to an improvement in treatment outcomes in patients with acromegaly. In the current study we determined the clinical features and recent therapeutic outcomes in ...
Zarychanski Ryan R University of Manitoba, Department of Internal Medicine, Section of Critical Care, University of Manitoba, ON2056-675 McDermot Ave, Winnipeg, Manitoba R3E 0V9, Canada. - - 2013
Hydroxyethyl starch is commonly used for volume resuscitation yet has been associated with serious adverse events, including acute kidney injury and death. Clinical trials of hydroxyethyl starch are conflicting. Moreover, multiple trials from one investigator have been retracted because of scientific misconduct. To evaluate the association of hydroxyethyl starch use ...
Cernusak Lucas A - - 2013
Leaf water becomes enriched in the heavy isotope (18) O through the process of transpiration. The leaf water (18) O signal is recorded in plant organic material (Barbour 2007), in atmospheric CO(2) via the activity of carbonic anhydrase (Farquhar et al. 1993), and in atmospheric O(2) through photosynthetic O(2) evolution ...
Schutting Susanne - - 2013
New indicators for optical CO2 sensors are synthesized in two steps from the commercially available diketo-pyrrolo-pyrrole (DPP) pigments Irgazin Ruby and Irgazin Scarlet. After introduction of bis(2-ethylhexyl) sulfonamide groups via a simple two-step synthesis the pigments are rendered highly soluble in organic solvents and in polymers and show pH-dependent absorption ...
Varni James W - - 2013
OBJECTIVES: In order to compare multidimensional fatigue research findings across age and gender subpopulations, it is important to demonstrate measurement invariance, that is, that the items from an instrument have equivalent meaning across the groups studied. This study examined the factorial invariance of the 18-item PedsQL™ Multidimensional Fatigue Scale items ...
Langdon Kristopher D KD Division of BioMedical Sciences, Memorial University, St. John's, Newfoundland and Labrador, - - 2013
Dementia is a major cause of morbidity in the western society. Pharmacological therapies to delay the progression of cognitive impairments are modestly successful. Consequently, new therapies are urgently required to improve cognitive deficits associated with dementia. We evaluated the effects of physical and cognitive activity on learning and memory in ...
Gattepaille L M LM Department of Evolutionary Biology, Evolutionary Biology Centre, Uppsala University, Uppsala, - - 2013
Reconstructing historical variation of population size from sequence and single-nucleotide polymorphism (SNP) data is valuable for understanding the evolutionary history of species. Changes in the population size of humans have been thoroughly investigated, and we review different methodologies of demographic reconstruction, specifically focusing on human bottlenecks. In addition to the ...
Nassiri Farshad - - 2013
The pituitary is the master endocrine gland of the body. It undergoes many changes after birth, and these changes may be mediated by the differentiation of pituitary stem cells. Stem cells in any tissue source must display (1) pluripotent capacity, (2) capacity for indefinite self-renewal, and (3) a lack of ...
Grüebler Martin U - - 2013
The microclimate of potential roost-sites is likely to be a crucial determinant in the optimal roost-site selection of endotherms, in particular during the winter season of temperate zones. Available roost-sites for birds and mammals in European high trunk orchards are mainly tree cavities, wood stacks and artificial nest boxes. However, ...
Cohen Sheldon S Department of Psychology, Carnegie Mellon University, 5000 Forbes Ave, Pittsburgh, PA 15213, USA. - - 2013
Although leukocyte telomere length is associated with mortality and many chronic diseases thought to be manifestations of age-related functional decline, it is not known whether it relates to acute disease in younger healthy populations. To determine whether shorter telomeres in leukocytes, especially CD8CD28- T cells, are associated with decreased resistance ...
Berg R M G - - 2013
It is a central principle in medical ethics that vulnerable patients are entitled to a degree of protection that reflects their vulnerability. In critical care research, this protection is often established by means of so-called proxy consent. Proxy consent for research participation constitutes a substituted judgement by a close relative ...
Zhao Li-Li - - 2013
The first investigation into two C[double bond, length as m-dash]O bonds of CO(2) reacting in one reaction through dual 1,3-dipolar cycloaddition of CO(2) with isocyanides and dialkyl acetylenedicarboxylates has been reported. The reaction proceeded efficiently at 80 °C at a pressure of 1 atm of CO(2), affording symmetric 1,6-dioxospiro[4,4]nonane-3,8-diene derivatives ...
Akel Burcu Semin - - 2013
PURPOSE: We aimed to determine the health-related quality of life (HRQL) of children with obstetrical brachial plexus palsy (OBPP) and examine its association with gender, age, injury level, injured side, and functional status. METHODS: We conducted a controlled, cross-sectional study including 70 children with OBPP. Fifty-two age-matched children without any ...
Derevensky Jeffrey L - - 2013
Despite legislative prohibitions, there is empirical evidence that youth gamble on both regulated and unregulated activities. The current survey was designed to assess teachers' awareness and attitudes regarding adolescent gambling and other high-risk behaviours. Three-hundred and ninety teachers from Ontario and Quebec, with experience teaching students aged 12-18, completed an ...
He Yizheng - - 2013
INTRODUCTION: In patients with programmable CSF shunt valves, the risk of unintentional valve adjustment associated with the environmental magnetic influence is ever present. We tested whether the iPad 3 with Smart Cover is capable of changing the setting of individual programmable valves ex vivo using direct fluoroscopic visualization. METHODS: The ...
Prakash Shiva S Department of Orthopaedics, Postgraduate Institute of Medical Education and Research, Chandigarh, - - 2013
A few animal studies have shown that IL-6 can serve as an early marker of fat embolism syndrome. The degree to which this is true in human trauma victims is unknown. In this clinical study, we sought to determine (1) whether elevated serum IL-6 levels at 6, 12, and 24 ...
Xiong G - - 2013
To assess the beneficial and adverse effects of orally therapies of Chinese herb formulae (CHF) for erectile dysfunction (ED), four electronic databases were searched until 23 June 2012. Randomised clinical trials testing CHF or combined with Western medicine therapy (WMT) against placebo, another different CHF and WMT were included. Study ...
Chen Chao - - 2013
We report the complementary resistive switching (CRS) behaviors in aluminum nitride (AlN)-based memory devices as the promising new material system for large-scale integration of passive crossbar arrays. By utilizing different electrodes (Cu, Pt, and TiN), CRS characteristics are demonstrated in both TiN/AlN/Cu/AlN/TiN electrochemical metallization cells and Pt/AlN/TiN/AlN/Pt ionic resistive switching ...
O'Ferrall Erin K - - 2013
Introduction: Hypertrophy of the nerve roots of the cauda equina may occur with both acquired and inherited neuropathies. Although selective nerve root involvement of the sensory roots has been described and termed chronic inflammatory sensory polyradiculoneuropathy (CISP), selective involvement of the proximal motor roots has not been described. Methods: Clinical, ...
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