Search Results
Results 401 - 450 of 1922
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Matsunaga Takuya - - 2013
In this paper, we propose a new computational method for efficient evaluation of the fluid mixing behaviour in a T-shaped micromixer with a rectangular cross section at high Schmidt number under steady state conditions. Our approach enables a low-cost high-quality simulation based on tracking of fluid particles for convective fluid ...
Gabryelska Marta Magdalena - - 2013
Hammerhead ribozyme is a versatile tool for down-regulation of gene expression in vivo. Due to its small size and high activity, it is used as a model for RNA structure-function relationship studies. Here we describe a new extended hammerhead ribozyme HH-2 with a tertiary stabilizing motif constructed on the basis ...
Avitabile C - - 2013
Cysteine-containing antimicrobial peptides of diverse phylogeny share a common structural signature, the γ core, characterized by a strong polarization of charges in two antiparallel β sheets. In this work, we analyzed peptides derived from the tomato defensin SolyC07g007760 corresponding to the protein γ core and demonstrated that cyclization of the ...
Race C P - - 2013
By simulating the passage of heavy ions along open channels in a model crystalline metal using semi-classical Ehrenfest dynamics we directly investigate the nature of non-adiabatic electronic effects. Our time-dependent tight-binding approach incorporates both an explicit quantum mechanical electronic system and an explicit representation of a set of classical ions. ...
Kano Osamu - - 2013
Whiteley et al.(1) reported that higher level of circulating markers of the acute inflammatory response in acute stroke were associated with higher temperatures in normal brain. They found no association between blood markers of inflammation and brain temperature in different regions of brain. The authors measured 3 markers of inflammation: ...
Ito Hisatoshi - - 2013
Although the quest for Earth's oldest rock is of great importance, identifying the youngest exposed pluton on Earth is also of interest. A pluton is a body of intrusive igneous rock that crystallized from slowly cooling magma at depths of several kilometers beneath the surface of the Earth. Therefore, the ...
Schmidt Barbara - - 2013
Theories of an optimal level of arousal suggest that underaroused humans seek stimulation to enhance their arousal. One way to increase arousal is risky behavior during gambling. In the current study, we show that the lower the participants' resting arousal, measured via resting heart rate, the riskier they acted in ...
Tanner-Smith Emily E - - 2013
This study reports findings from a systematic review and meta-analysis of literature examining the effects of school dropout prevention and intervention programs on students' school absenteeism outcomes. The meta-analysis synthesized 74 effect sizes measuring posttest differences in school absenteeism outcomes for youth enrolled in dropout prevention programs relative to a ...
Schaeffer David J - - 2013
Cognitive control is required for correct antisaccade performance. High antisaccade error rates characterize certain psychiatric disorders, but can be highly variable, even among healthy groups. Antisaccade data were acquired from a large sample of healthy undergraduates, and error rate was quantified. Participants who reliably made few errors (good, n = 13) or ...
Lin He - - 2013
Trinitromethyl-substituted aminotetrazoles with -NH(2), -NO(2), -N(3), and -NHC(NO(2))(3) groups were investigated at the B3LYP/6-31G(d) level of density functional theory. Their sublimation enthalpies, thermodynamic properties, and heats of formation were calculated. The thermodynamic properties of these compounds increase with temperature as well as with the number of nitro groups attached to ...
Chi Yingkai - - 2013
Although some evidence has been documented on EGFR/PI3K mediation of Akt activation in breast cancers, ILK and DNA-PK have not been investigated so far. The aim of this study was to analyze the expression of phosphorylated Akt (pAkt) in breast cancer, with respect to its upstream regulators. The immunostaining of ...
Helvik Anne-Sofie - - 2013
ABSTRACT: BACKGROUND: The risk factors for mortality after hospitalization in older persons are not fully understood. The aim of the present study was to examine the three-year (1,096 days) mortality in previously hospitalized older patients from rural areas, and to explore how objectively and self-reported health indicators at baseline were ...
Rianthavorn Pornpimol - - 2013
BACKGROUND: Vitamin D insufficiency is related to erythropoietin resistance in chronic kidney disease (CKD). This study was conducted to evaluate the effect of ergocalciferol on the dose of erythrocyte-stimulating agent (ESA) administered to children with CKD stage 5 and vitamin D insufficiency. METHODS: Twenty patients aged <18 years with CKD stages ...
Kato Tsugiko - - 2013
The Japanese medical device industry's stagnation over the years can be attributed to the uncertainty related to device development. The purpose of this study is to identify the major factors that impact development. We studied the ventricular assist device EVAHEART through interviews with the persons involved and created a development ...
Zhou Jue - - 2013
In the last decades, cases of poisoning due to herbal medicines have occurred in many countries; Chinese herbal medicines (CHMs) are occasionally involved. The experience gained from traditional use is efficient to detect immediate or near-immediate relationship between administration and toxic effects but is quite unlikely to detect medium- to ...
Mazur Mykola - - 2013
The synthesis of multifunctional magnetic nanoparticles (MF-MPs) is one of the most active research areas in advanced materials as their multifunctional surfaces allow conjugation of biological and chemical molecules, thus making it possible to achieve target-specific diagnostic in parallel to therapeutics. We report here a simple strategy to integrate in ...
Ogawa Haruhiko - - 2013
The cough-related laryngeal sensation of mucus in the throat (SMIT) is usually overlooked because it is not reflected by physiological examinations or cough-specific questionnaires. Our results suggested that SMIT can predict the presence of fungal colonization in chronic cough patients. We propose that, next to "cough" or "sputum," SMIT may ...
Gamella M - - 2013
The preparation, characterization and performance evaluation of an amperometric affinity disposable magnetosensor, based on the use of a recombinant penicillin-binding protein (PBP) and screen-printed carbon electrodes (SPCEs), for the specific detection and quantification of β-lactam antibiotic residues in milk are reported. The PBP was immobilized onto His-Tag-Isolation-modified magnetic beads (His-Tag-Isolation-MBs), ...
Jubault Mélanie - - 2013
To date, studies of the molecular basis of disease resistance mainly focused on qualitative resistance. However, deciphering mechanisms underlying quantitative resistance could lead to insights into the relationship between qualitative and quantitative resistance and guide the utilization of these two types of resistance to produce durably resistant cultivars. A functional ...
Haridas Anjana A Ophthalmology Department, Hinchingbrooke Healthcare NHS Trust, Huntingdon, UK. - - 2013
The association between intraoperative floppy iris syndrome (IFIS) and tamsulosin has been well-described. The rate of IFIS in association with other α-1 antagonists needs further clarification. The objective of this study was to determine the incidence of IFIS and associated cataract surgery complications in patients taking tamsulosin or doxazosin. Patients ...
Garg Scot - - 2013
Drug-eluting stents (DES) have revolutionized the practice of interventional cardiology over the past decade. Although their efficacy has never been called into question, concerns have been raised regarding their safety, particularly with respect to very late stent thrombosis. These valid concerns have prompted extensive research into improving stent safety, with ...
Cheng Yan - - 2013
Autophagy, a cellular process of "self-eating" by which intracellular components are degraded within the lysosome, is an evolutionarily conserved response to various stresses. Autophagy is associated with numerous patho-physiological conditions, and dysregulation of autophagy contributes to the pathogenesis of a variety of human diseases including cancer. Depending on context, activation ...
Zhao Jun - - 2013
Porous anatase TiO(2) microspheres composed of {010}-faceted nanobelts were synthesized through simple thermal treatment of a titanium glycerolate precursor. The as-prepared TiO(2) nanomaterial was shown to serve as an efficient photocatalyst for H(2) evolution, and its activity was more than twice that of the benchmark P25 TiO(2).
Yamamoto Keiko K Department of Health and Psychosocial Medicine, School of Medicine, Aichi Medical University, 1-1 Yazako Karimata, Nagakute, Aichi, 480-1195, - - 2013
The multiple sleep latency test (MSLT) has been employed extensively in clinical and research settings as a gold standard for objectively measuring sleepiness. In a general population or in a variety of work settings, however, a more convenient, rapidly administered measuring method is preferable. We examined the potential utility of ...
Rodriguez David - - 2013
Pneumopericardium is a rare clinical finding with various etiologies. Pneumopericardium ranges from an asymptomatic to life-threatening condition, e.g., in cases of cardiac tamponade. The underlying etiology should be sought so that treatment can be expedited. Pneumopericardium may result from traumatic and nontraumatic etiologies. Although the mortality associated with pneumopericardium is ...
Llucià-Valldeperas A - - 2013
A major challenge of cardiac tissue engineering is directing cells to establish the physiological structure and function of the myocardium being replaced. Our aim was to examine the effect of electrical stimulation on the cardiodifferentiation potential of cardiac adipose tissue-derived progenitor cells (cardiac ATDPCs). Three different electrical stimulation protocols were ...
O'Hare Fm - - 2013
Toll-Like Receptors are vital transmembrane receptors which initiate the innate immune response to many micro-organisms. The discovery of these receptors has improved our understanding of host-pathogen interactions and are important in the pathogenesis of multiple neonatal conditions such as sepsis and brain injury. TLRs, especially TLR 2 & 4 are ...
Robinson William H WH VA Palo Alto Health Care System, 3801 Miranda Ave, Palo Alto, CA 94304, USA. - - 2013
The use of biomarkers is becoming increasingly intrinsic to the practice of medicine and holds great promise for transforming the practice of rheumatology. Biomarkers have the potential to aid clinical diagnosis when symptoms are present or to provide a means of detecting early signs of disease when they are not. ...
Ruiz-Salinas Inna - - 2013
We have recently reported that quinpirole (a D(2)-like receptor agonist) inhibits the vasopressor sympathetic outflow in pithed rats via sympatho-inhibitory D(2)-like receptors. Since D(2)-like receptors consist of D(2), D(3) and D(4) receptor subtypes, this study investigated whether these subtypes are involved in the above quinpirole-induced sympatho-inhibition by using antagonists of ...
Frey Simon - - 2013
We use longitudinal patient-level data from a German sickness fund with 7.26 million insured in a Markov-simulation model to assess the cost-effectiveness of long-acting injectable risperidone (LAI-RIS) compared with long-acting injectable flupentixol (LAI-FLX) in the long-term management of schizophrenia. We simulate treatment costs from the payer's perspective, hospitalization, the probability to ...
Zhang Xiuyun - - 2013
The edge of two dimensional (2D) graphene, as the surface of a three dimensional (3D) crystal, plays a crucial role in the determination of its physical, electronic and chemical properties and thus has been extensively studied recently. In this review, we summarize the recent advances in the study of graphene ...
Pankuweit Sabine - - 2013
The aetiology of pericardial effusion has been generally assessed by clinical work-up only, which leaves a large cohort of patients with "idiopathic" effusions virtually undiagnosed. In accordance with the ESC guidelines, this contribution intends to change this attitude. After therapeutic or diagnostic pericardiocentesis of 259 patients with large to moderate ...
Park Soo-An SA Department of Orthopedic Surgery, Uijeongbu St. Mary's Hospital, The Catholic University of Korea College of Medicine, 271, Cheonbo-ro, Ujeongbu-si, Gyeonggi-do 480-717, South Korea. - - 2013
To develop a clinically relevant anterior cervical approach (ACA) to the C2-3 level. Frequently encountered nerves [hypoglossal (HyN), internal (ISLN) and external superior laryngeal nerves (ESLN)] and vessels [lingual (LiA), superior laryngeal (SLA) and superior thyroid arteries (STA)] in the field of high ACA and the anatomic spatial markers [submandibular ...
Zhao Yin - - 2013
PROBLEM: The purpose of this study was to evaluate the impact of mechanical stretch caused by uterine contraction and progesterone (P(4) ) on decidual cells (DC), neutrophil chemokines, and MMP-1 expression. METHOD OF STUDY: DC were cultured, and cyclic stretch was applied using a computer-operated cell stretch system. Interleukin (IL)-8, ...
Marwan Mohamed - - 2013
Cardiac computed tomography (CT) allows accurate and detailed analysis of the anatomy of the aortic root and valve, including quantification of calcium. We evaluated the correlation between different CT parameters and the degree of post-procedural aortic regurgitation (AR) after transcatheter aortic valve implantation (TAVI) using the balloon-expandable Edwards Sapien prosthesis. ...
Jaser Sarah S - - 2013
The purpose of this study was to describe coping in mothers of adolescents with type 1 diabetes and to examine the association among mothers' diabetes-related stress and coping strategies and maternal psychological distress (e.g., symptoms of anxiety and depression), adolescent adjustment (e.g., symptoms of depression, quality of life), diabetes-related family ...
Pössel Patrick - - 2013
Significant associations of private prayer with mental health have been found, while mechanisms underlying these associations are largely unknown. This cross-sectional online study (N = 325, age 35.74, SD 18.50, 77.5 % females) used path modeling to test if trust-based beliefs (whether, when, and how prayers are answered) mediated the associations of prayer ...
Navarese Eliano P - - 2013
The optimal timing of coronary intervention in patients with non-ST-segment elevation acute coronary syndromes (NSTE-ACSs) is a matter of debate. Conflicting results among published studies partly relate to different risk profiles of the studied populations. To do the most comprehensive meta-analysis of current evidence on early versus delayed invasive treatment ...
Koyama Sumihiro - - 2013
We developed an electrical modulation method for attachment and detachment of microorganisms. Living microorganisms suspended in non-nutritive media such as PBS(-) and artificial seawater were attracted by and selectively attached to indium tin oxide (ITO)/glass electrode regions to which a negative potential was applied. The microorganisms suspended in LB medium ...
Chen Shu-Huey - - 2013
Allogeneic hematopoietic stem cell transplantation is now an important treatment for numerous diseases. Donation of hematopoietic stem cells, either through bone marrow (BM) harvesting or peripheral blood stem cell (PBSC) collection, is a well-established and generally accepted procedure. The BM is aspirated from the posterior iliac crest under spinal or ...
Bassotti Gabrio - - 2013
Chronic constipation is a commonly encountered symptom in everyday clinical practice, and numerous drugs are available for its medical treatment. However, there are several misconceptions that still often limit an effective approach, as well as the fact that it is older but effective treatments are sometimes neglected in favor of ...
Ito Katsura - - 2013
In Tetranychus spider mites (Acari: Tetranychidae), diapausing females have a conspicuous orange body colour, which is used as an indicator of diapause induction in many laboratory studies. However, to which extent body colour reflects reproductive activity is scarcely investigated. In this study, we investigated the relationship between body colour, reproductive ...
Franzin Alberto - - 2013
BACKGROUND: The reported AVMs obliteration rate after Gamma Knife radiosurgery (GKS) ranges from 70 to 94 %. The objective of the present study was to assess prognostic factors predictive for cerebral AVMs obliteration in 127 patients who underwent GKS. METHODS: The AVMs were classified according to the Spetzler-Martin classification. Twenty-one cases ...
Aubé William - - 2013
Music is a powerful tool for communicating emotions which can elicit memories through associative mechanisms. However, it is currently unknown whether emotion can modulate memory for music without reference to a context or personal event. We conducted three experiments to investigate the effect of basic emotions (fear, happiness, and sadness) ...
Madhok Brijesh M - - 2013
Debridement is a crucial component of wound management. Traditionally, several types of wound debridement techniques have been used in clinical practice such as autolytic, enzymatic, biodebridement, mechanical, conservative sharp and surgical. Various factors determine the method of choice for debridement for a particular wound such as suitability to the patient, ...
Peng Yongbo - - 2013
In this study, the partial filling technique on both polycationic polymer hexadimethrine bromide modified capillary and eCAP neutral capillary were systematically compared in order to enhance the enantioseparation ability of bromobalhimycin as CE additive. The separation conditions, such as pH, the plug length and the concentration of bromobalhimycin, etc., were ...
Billè Andrea - - 2013
OBJECTIVE: To describe the long-term results, quality of life and chronic pain after chest wall fixation for traumatic rib fracture using a quality of life (QOL) score and a numeric pain score. METHODS: Retrospective analysis of 10 consecutive patients who underwent surgery for rib fractures after trauma and reconstruction between ...
Perez Edith A - - 2013
A comprehensive, blinded, pathology evaluation of HER2 testing in HER2-positive/negative breast cancers was performed among three central laboratories. Immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) analyses were performed on 389 tumor blocks from three large adjuvant trials: N9831, BCIRG-006, and BCIRG-005. In 123 cases, multiple blocks were examined. HER2 ...
Wu Yi-Jen - - 2013
A 48-year-old man presented with episodic paraplegia and stiffness of hands, face, and tongue, along with eyelid myotonia when exposed to cold temperature, which he had since childhood. Eyelid myotonia was evoked either by exposure to cold weather (video on the Neurology® Web site at www.neurology.org and figure 1) or ...
Hwang Seung Jun - - 2013
Core@shell electrocatalysts for fuel cells have the advantages of a high utilization of Pt and the modification of its electronic structures toward enhancement of the activities. In this study, we suggest both a theoretical background for the design of highly active and stable core@shell/C and a novel facile synthetic strategy ...
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