Search Results
Results 401 - 450 of 1922
< 4 5 6 7 8 9 10 11 12 13 14 >
Bernat James L - - 2013
Circulatory-respiratory or brain tests are widely accepted for definition and determination of death, but have several controversial issues. Both determinations have been stimulated by organ donation, but must be valid independently of this process. Current controversies in brain death include whether the definition is conceptually coherent, whether the whole-brain or ...
Dede K - - 2013
Patients with metastatic colorectal cancer receive chemotherapy prior liver resection more and more frequently. This preoperative treatment has many effects which have to be analysed, like the safety of liver resection, toxicity, tissue regeneration, radiological and pathological response and survival data. The aim of the study was to evaluate the ...
Rowland Kate - - 2013
QUESTION Does a clinical prediction rule based on data collected at hospital admission predict risk for death and severe disability after acute ischemic stroke? METHODS DESIGN Registry-based cohort study with individual patient linkage to administrative databases and separate derivation and validation cohorts. SETTING 11 regional stroke centers in Ontario, Canada. ...
Irvine Gail V - - 2013
Probability-based designs reduce bias and allow inference of results to the pool of sites from which they were chosen. We developed and tested probability-based designs for monitoring marine rocky intertidal assemblages at Glacier Bay National Park and Preserve (GLBA), Alaska. A multilevel design was used that varied in scale and ...
Rybi-SzumiƄska Agnieszka - - 2013
AIM: The objective of this study was to establish age-dependent urine NGAL (neutrophil gelatinase associated lipocalin) /creatinine ratio values in healthy children and adolescents. METHODS: The study was performed using a random sample of 172 healthy children and adolescents (M - 88, F - 84), aged median 9.75 (0.2 - ...
Berlowska Joanna - - 2013
The adhesion of cells to solid supports is described as surface-dependent, being largely determined by the properties of the surface. In this study, ceramic surfaces modified using different organosilanes were tested for proadhesive properties using industrial brewery yeast strains in different physiological states. Eight brewing strains were tested: bottom-fermenting Saccharomyces ...
Guo Zelei - - 2013
The maximum oscillation frequency (fmax) quantifies the practical upper bound for useful circuit operation. We report here an fmax of 70 GHz in transistors using epitaxial graphene grown on the C-face of SiC. This is a significant improvement over Si-face epitaxial graphene used in the prior high frequency transistor studies, ...
Pragasam Samuel Joshua - - 2013
OBJECTIVE: This study was conducted to evaluate the effect of p-Coumaric acid, a common dietary phenol, on monosodium urate crystal-induced inflammation in rats-an experimental model for acute gouty arthritis. METHODS: Paw edema, levels/activities of lysosomal enzymes, lipid peroxidation, enzymic antioxidants and a histopathological examination of ankle joints were evaluated in ...
Marques Carlos F C - - 2013
Aqueous biphasic systems (ABS) using ionic liquids (ILs) offer an alternative approach for the extraction, recovery and purification of biomolecules through their partitioning between two aqueous liquid phases. In this work, the ability of a wide range of ILs to form ABS with aqueous solutions of Na(2) CO(3) was evaluated. ...
Opletal George - - 2013
A structural study is presented of ab initio molecular dynamics simulations of Ge-As-Se chalcogenide glasses performed at the same mean coordination number but differing stoichiometry ranging between Se rich and Se poor glasses. Starting configurations are generated via Reverse Monte Carlo (RMC) simulations of Extended X-ray Absorption Fine Structure (EXAFS) ...
Seijo Susana - - 2013
OBJECTIVES:Idiopathic portal hypertension (IPH) is a rare cause of portal hypertension that lacks a specific diagnostic test. Requiring ruling-out other causes of portal hypertension it is frequently misdiagnosed. This study evaluates whether using high-throughput techniques there is a metabolomic profile allowing a noninvasive diagnosis of IPH.METHODS:Thirty-three IPH patients were included. ...
Han Tao - - 2013
Retinol-binding protein 4 (RBP4) is closely associated with a variety of abnormal glycolipid metabolism diseases such as insulin resistance, obesity, diabetes mellitus, and metabolic syndrome. Part 1 Twenty-four male C57/B6 mice were randomly divided into a normal control group (group C, n = 8), a gallstone group (group G, n = 8), and a ...
Al-Foheidi Meteb - - 2013
Breast cancer is the most common cancer in women worldwide. The disease remains a public health concern as recent evidence indicates that the breast cancer burden has increased mainly in developing and low-income countries (DLICs). Despite the demonstrated benefits, the debate about the real benefits and harms of breast cancer ...
Sato Yukie - - 2013
Closely related species often show adjacent geographic distributions, albeit with some overlap. This contiguity is thought to result from secondary contact between (spatially separated) diverging groups or from parapatric speciation. Fights between males of closely related species will affect their chance to mate with females of the other species, which ...
O'Leary Cm - - 2013
OBJECTIVES: To examine alcohol-use disorders in pregnant women and the extent of under-reporting. DESIGN: Population-based cohort study. SETTING: Western Australia. POPULATION: Women with a birth recorded on the Western Australian Midwives Notification System (1985-2006). METHODS: Mothers with an International Classification of Diseases 9/10 alcohol-related diagnosis, indicating heavy alcohol consumption, recorded ...
Yun Y E - - 2013
Abstract 1. Rationale: Tissue-to-plasma partition coefficients (K(p)) that characterize the tissue distribution of a drug are important input parameters in physiologically based pharmacokinetic (PBPK) models. The aim of this study was to develop an empirically derived K(p) prediction algorithm using input parameters that are available early in the investigation of ...
Yoshimoto Akihiro - - 2013
OBJECTIVE: We perform bilateral pulmonary artery banding (BPAB) combined with postoperative percutaneous pulmonary artery balloon dilatation (PABD) as stage I palliation for severe congenital heart diseases. The objective of this study was to evaluate the efficacy of our management strategy for the treatment of severe congenital heart diseases. METHODS: From ...
Paolino Nathalie - - 2013
QUESTION Do nonpharmacologic interventions involving family caregivers of community-dwelling patients with dementia reduce neuropsychiatric symptoms and caregivers' adverse reactions to neuropsychiatric symptoms? REVIEW SCOPE Included studies compared nonpharmacologic interventions involving caregivers (live-in family member) of patients with dementia with control. Studies of respite care, drug therapy, or patients with schizophrenia ...
Lee Won-Heong - - 2013
Efficient regeneration of NADPH is one of the limiting factors that constrain the productivity of biotransformation processes. In order to increase the availability of NADPH for enhanced biotransformation by engineered Escherichia coli, modulation of the pentose phosphate pathway and amplification of the transhydrogenases system have been conventionally attempted as primary ...
Silva Lucelia C - - 2013
We propose that canine visceral leishmaniasis (CVL) is a systemic fibrotic disease, as evidenced by the wide distribution of fibrosis that we have found in the dogs suffering from chronic condition. The inflammatory cells apparently direct fibrosis formation. Twenty-four cases (symptomatic dogs) were identified from a total of one hundred ...
Zalla Tiziana - - 2013
In the present study, we investigated the ability to parse familiar sequences of action into meaningful events in young individuals with autism spectrum disorders (ASDs), as compared to young individuals with typical development (TD) and young individuals with moderate mental retardation or learning disabilities (MLDs). While viewing two videotaped movies, ...
Zhao Jinggeng - - 2013
The phase transition, amorphization, and crystallization behaviors of the topological insulator bismuth selenide (Bi(2)Se(3)) were discovered by performing in situ high-pressure angle-dispersive x-ray diffraction experiments during an increasing, decreasing, and recycling pressure process. In the compression process, Bi(2)Se(3) transforms from the original rhombohedral structure (phase I(A)) to a monoclinic structure (phase II) ...
Das Prithwiraj - - 2013
The endoparasitic wasps (Hymenoptera: Braconidae), Microplitis croceipes (specialist) and Cotesia marginiventris (generalist), are parasitoids of lepidopteran larvae and differ in their degree of host specificity. Recent studies have reported key differences between the two species in the abundance of antennal olfactory sensilla and their response to host-related volatiles. Here, we ...
Ren Hui Jun - - 2013
Although it has been known for many years that Trichinella spiralis initiates infection by penetrating the columnar epithelium of the small intestine, the mechanisms by which T. spiralis infective larvae recognize and invade the intestinal epithelial cells (IECs) are unknown. It is speculated that the molecular interactions between the parasite ...
Buda Roberto - - 2013
Osteochondral lesions of the knee (OLK) are a common cause of knee pain and associated diseases. A new bone-marrow-derived mesenchymal stem cells technique has been developed for the treatment of OLK. 30 patients with OLK underwent arthroscopic one-step procedure. The bone marrow was harvested from the patients' posterior iliac crest ...
Manresa Carolina - - 2013
AIM: To establish an image analysis procedure for measuring the bone-to-implant contact (BIC) by a systematic non-subjective approach based on backscattered scanning electron microscopy (BS-SEM) images. MATERIAL AND METHODS: A total of 36 dental implants (9 mm length, Ø 4.0 mm with a SBM surface) were implanted in six beagle dog mandibles. ...
Mamedov Ibrahim Garib - - 2013
Molecular dynamics of benzoxazepin, oxime, pyrazole, and thiosemicarbazone derivatives of some flavanones have been investigated in a solution using NMR. The results confirm the formation of different O-H···O, O-H···N, N···H-N type intramolecular hydrogen bonds in the pyrazole and oxime molecules. The rotational barrier energy and energy of intramolecular hydrogen bonds ...
Yamamoto Keiko - - 2013
OBJECTIVES: The multiple sleep latency test (MSLT) has been employed extensively in clinical and research settings as a gold standard for objectively measuring sleepiness. In a general population or in a variety of work settings, however, a more convenient, rapidly administered measuring method is preferable. We examined the potential utility ...
Rodriguez David - - 2013
Pneumopericardium is a rare clinical finding with various etiologies. Pneumopericardium ranges from an asymptomatic to life-threatening condition, e.g., in cases of cardiac tamponade. The underlying etiology should be sought so that treatment can be expedited. Pneumopericardium may result from traumatic and nontraumatic etiologies. Although the mortality associated with pneumopericardium is ...
Llucià-Valldeperas A - - 2013
A major challenge of cardiac tissue engineering is directing cells to establish the physiological structure and function of the myocardium being replaced. Our aim was to examine the effect of electrical stimulation on the cardiodifferentiation potential of cardiac adipose tissue-derived progenitor cells (cardiac ATDPCs). Three different electrical stimulation protocols were ...
O'Hare Fm - - 2013
Toll-Like Receptors are vital transmembrane receptors which initiate the innate immune response to many micro-organisms. The discovery of these receptors has improved our understanding of host-pathogen interactions and are important in the pathogenesis of multiple neonatal conditions such as sepsis and brain injury. TLRs, especially TLR 2 & 4 are ...
Robinson William H - - 2013
The use of biomarkers is becoming increasingly intrinsic to the practice of medicine and holds great promise for transforming the practice of rheumatology. Biomarkers have the potential to aid clinical diagnosis when symptoms are present or to provide a means of detecting early signs of disease when they are not. ...
Ruiz-Salinas Inna - - 2013
We have recently reported that quinpirole (a D(2)-like receptor agonist) inhibits the vasopressor sympathetic outflow in pithed rats via sympatho-inhibitory D(2)-like receptors. Since D(2)-like receptors consist of D(2), D(3) and D(4) receptor subtypes, this study investigated whether these subtypes are involved in the above quinpirole-induced sympatho-inhibition by using antagonists of ...
Frey Simon - - 2013
We use longitudinal patient-level data from a German sickness fund with 7.26 million insured in a Markov-simulation model to assess the cost-effectiveness of long-acting injectable risperidone (LAI-RIS) compared with long-acting injectable flupentixol (LAI-FLX) in the long-term management of schizophrenia. We simulate treatment costs from the payer's perspective, hospitalization, the probability to ...
Zhang Xiuyun - - 2013
The edge of two dimensional (2D) graphene, as the surface of a three dimensional (3D) crystal, plays a crucial role in the determination of its physical, electronic and chemical properties and thus has been extensively studied recently. In this review, we summarize the recent advances in the study of graphene ...
Pankuweit Sabine - - 2013
The aetiology of pericardial effusion has been generally assessed by clinical work-up only, which leaves a large cohort of patients with "idiopathic" effusions virtually undiagnosed. In accordance with the ESC guidelines, this contribution intends to change this attitude. After therapeutic or diagnostic pericardiocentesis of 259 patients with large to moderate ...
Zhao Yin - - 2013
PROBLEM: The purpose of this study was to evaluate the impact of mechanical stretch caused by uterine contraction and progesterone (P(4) ) on decidual cells (DC), neutrophil chemokines, and MMP-1 expression. METHOD OF STUDY: DC were cultured, and cyclic stretch was applied using a computer-operated cell stretch system. Interleukin (IL)-8, ...
Marwan Mohamed - - 2013
Cardiac computed tomography (CT) allows accurate and detailed analysis of the anatomy of the aortic root and valve, including quantification of calcium. We evaluated the correlation between different CT parameters and the degree of post-procedural aortic regurgitation (AR) after transcatheter aortic valve implantation (TAVI) using the balloon-expandable Edwards Sapien prosthesis. ...
Jaser Sarah S - - 2013
The purpose of this study was to describe coping in mothers of adolescents with type 1 diabetes and to examine the association among mothers' diabetes-related stress and coping strategies and maternal psychological distress (e.g., symptoms of anxiety and depression), adolescent adjustment (e.g., symptoms of depression, quality of life), diabetes-related family ...
Pössel Patrick - - 2013
Significant associations of private prayer with mental health have been found, while mechanisms underlying these associations are largely unknown. This cross-sectional online study (N = 325, age 35.74, SD 18.50, 77.5 % females) used path modeling to test if trust-based beliefs (whether, when, and how prayers are answered) mediated the associations of prayer ...
Benarroch Eduardo E - - 2013
Maintenance of intracellular chloride (Cl(-)) concentration ([Cl(-)]i) is critical for volume regulation and determines the effects of γ-aminobutyric acid (GABA) and glycine-mediated neurotransmission. Cation-chloride cotransporters (CCC) transport Cl(-) together with sodium (Na(+)), potassium (K(+)), or both, across plasma membranes and have an important role in maintenance [Cl(-)]i. The CCC in ...
Debast Sylvia B - - 2013
OBJECTIVES: In November 2008, a study was performed with support from the European Centre for Disease Prevention and Control (ECDC) to obtain an overview of Clostridium difficile infections (CDIs) in European hospitals. A collection of 398 C. difficile isolates obtained from this hospital-based survey was utilized to identify antimicrobial susceptibility ...
Callaghan Connor M - - 2013
OBJECTIVES: To study the effects of partial bladder outlet obstruction on the cell's anti-oxidant defense mechanisms, superoxide dismutase and catalase, in order to elucidate how the bladder responds to oxidative stress. METHODS: Four groups of eight rabbits were subjected to partial bladder outlet obstruction for 4, 8 and 12 weeks. Eight ...
Forster Anne - - 2013
RATIONALE: Despite recognition of the importance of the longer-term consequences of stroke, services addressing these needs remain poorly developed. There are persuasive arguments that a community-based orientation to poststroke care, to assess, support, and coordinate relevant services, might be more helpful in minimizing longer-term stroke morbidity. To address this, an ...
Lo Vasco V R - - 2013
The signaling system of phosphoinositides (PI) is involved in a variety of cell and tissue functions, including membrane trafficking, ion channel activity, cell cycle, apoptosis, differentiation, and cell and tissue polarity. Recently, PI and related molecules, such as the phosphoinositide-specific phospholipases C (PI-PLCs), main players in PI signaling were supposed ...
Di Meo Florent - - 2013
This work rationalizes the glucuronidation process (one of the reactions of the phase II metabolism) for drugs having a carboxylic acid moiety. At this stage, acylglucuronides (AG) metabolites are produced, that have largely been reported in the literature for various drugs (e.g., mycophenolic acid (MPA), diclofenac, ibuprofen, phenylacetic acids). The ...
Velino Biagio - - 2013
The rotational signatures of methyl pyruvate as an impurity have been accidentally found and its rotational spectrum was assigned while recording the microwave spectrum of a 98% Sigma-Aldrich sample of methyl (S)-(-)-lactate with the pulsed jet Fourier transform microwave technique.
Ostergaard Kristine H - - 2013
The giraffe heart has a relative mass similar to other mammals, but generates twice the blood pressure to overcome the gravitational challenge of perfusing the cerebral circulation. To provide insight as to how the giraffe left ventricle (LV) is structurally adapted to tackle such a high afterload, we performed a ...
Rozenberg Serge - - 2013
Postmenopausal hormone therapy (PMHT) is used for the relief of menopausal symptoms, but the dosage has varied greatly throughout its existence. By the end of the 1990s, PMHT was mainly used to prevent chronic diseases such as osteoporosis, coronary heart disease and dementia, and large prevention trials were undertaken in ...
Kranenburg H C - - 2013
Both spondylosis and diffuse idiopathic skeletal hyperostosis (DISH) are prevalent in humans and are considered distinct entities. Nowadays, the term spondylosis is in the biomedical literature mostly used when also degenerative disc disease is present. In companion animals, many reports on spondylosis, often without intervertebral disc degeneration, are described. The ...
< 4 5 6 7 8 9 10 11 12 13 14 >