Search Results
Results 351 - 400 of 1922
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Dinglin Xiao-Xiao - - 2013
Pemetrexed-based chemotherapy presented about 40 % response rate (RR) on brain lesions of non-small cell lung cancer (NSCLC). But whole brain radiotherapy (WBRT) is still the standard treatment when surgery or radio-surgery is not feasible. This trial evaluated the efficacy and safety and efficacy of pemetrexed-cisplatin plus concurrent WBRT in this ...
Klak Marie-Cécile - - 2013
The release of molecules entrapped within biogels is dictated by diffusion laws. Innovative biogel architectures are conceived and tested to control small molecule delivery from gelatin gels. The ionic interactions modulate the release of small molecules. Alginate is then added to gelatin gels and further hydrolyzed; the influence of viscosity ...
De Clippeleir Haydée - - 2013
Energy-positive sewage treatment can be achieved by implementation of oxygen-limited autotrophic nitrification/denitrification (OLAND) in the main water line, as the latter does not require organic carbon and therefore allows maximum energy recovery through anaerobic digestion of organics. To test the feasibility of mainstream OLAND, the effect of a gradual temperature ...
Patterson P - - 2013
PURPOSE: The current study sought to establish the psychometric properties of the revised Offspring Cancer Needs Instrument (OCNI) when completed by a large sample of young people impacted by parental cancer recruited from multiple settings. METHODS: The psychometric properties were evaluated with 256 young people aged between 12 and 24 ...
Zhang Yan-Jun - - 2013
The purposes of this study were to investigate the effects of B cell translocation gene 2 (BTG2) on the proliferation, apoptosis, and invasion of triple-negative breast cancer and to provide an experimental basis for the future treatment of human triple-negative breast cancer. A pcDNA3.1-BTG2 eukaryotic expression vector was constructed and ...
Berglund Sean P - - 2013
A new dispenser and scanner system is used to create and screen Bi-M-Cu oxide arrays for cathodic photoactivity, where M represents 1 of 22 different transition and post-transition metals. Over 3000 unique Bi : M : Cu atomic ratios are screened. Of the 22 metals tested, 10 show a M-Cu oxide with higher photoactivity ...
Goldenholz Daniel M - - 2013
Coccidioidal meningoencephalitis often carries a poor prognosis.(1) Brain imaging can reveal focal enhancement at the basal cisterns, infarction, and communicating hydrocephalus.(2) A 38-year-old HIV-negative Korean man with a history of CSF- and serum-confirmed coccidioidal meningitis, receiving chronic antifungal therapy, presented with a first generalized tonic-clonic seizure. CSF demonstrated pleomorphic leukocytosis, ...
Legramandi Mario A - - 2013
In an ideal elastic bounce of the body, the time during which mechanical energy is released during the push equals the time during which mechanical energy is absorbed during the brake, and the maximal upward velocity attained by the center of mass equals the maximal downward velocity. Deviations from this ...
Paredes Marco - - 2013
The in vitro and in vivo effect of prolactin (PRL) on kidney macrophages from Atlantic salmon (Salmo salar) was investigated under the assumption that PRL stimulates immune innate response in mammals. Kidney macrophages were treated two ways: first, cultured in RPMI 1640 medium containing 10, 25, 50 and 100 ng/mL of ...
Weiser Thomas G - - 2013
All surgeons want the best, safest care for their patients, but providing this requires the complex coordination of multiple disciplines to ensure that all elements of care are timely, appropriate, and well organized. Quality-improvement initiatives are beginning to lead to improvements in the quality of care and coordination amongst teams ...
Guan Xiangyu - - 2013
Pollution of groundwater with chlorinated aliphatic hydrocarbons (CAHs) is a serious environmental problem which is threatening human health. Microorganisms are the major participants in degrading these contaminants. Here, groundwater contaminated for a decade with CAHs was investigated. Numerical simulation and field measurements were used to track and forecast the migration ...
Ellis Mesha L - - 2013
The researchers longitudinally assessed parent and child levels of engagement in an evidence-based preventive intervention for children. The sample included 114 fifth graders with aggressive, disruptive behaviors and their parents who participated in the Coping Power Program. Findings indicate that levels of engagement differentially fluctuated for children and parents throughout ...
Kannieappan Lavern M - - 2013
ABSTRACT: BACKGROUND: It is estimated that between 34% and 50% of Australian women entering pregnancy are overweight and obese, which is associated with an increased risk in complications for both the woman and her infant. Current tools used in clinical and research practice for measuring body composition include body mass ...
Sharnin V A - - 2013
The formation constants of the nicotinamide H-complexes with protonic solvents such as water and ethanol in aqueous dimethyl sulfoxide and aqueous ethanol were determined using (13) C NMR data. Free Gibbs energy of nicotinamide donor center (nitrogen heteroatom) solvation was calculated. Gibbs energy of entire nicotinamide molecule solvation was shown ...
Norrie John - - 2013
OBJECTIVES: We investigated the treatment effects reported from a high-quality randomized controlled trial of cognitive behavioural therapy (CBT) for 106 people with borderline personality disorder attending community-based clinics in the UK National Health Service - the BOSCOT trial. Specifically, we examined whether the amount of therapy and therapist competence had ...
Cingel Vladimir - - 2013
Poland syndrome is a rare congenital anomaly described by Sir Alfred Poland over 170 years ago. Combination of unilateral aplasia of the sternocostal head of musculus pectoralis major, and an ipsilateral hypoplastic hand with simple syndactyly and short fingers is typical for this condition. It occurs more frequent among males, and ...
Taniguchi Chika - - 2013
The aim of this study was to develop new dipyridamole (DP) salts with pH-independent solubility for improving oral bioavailability under hypochlorhydria. Salt screening was carried out using nine counterions by the temperature gradient method. Six DP salts were obtained, and there was marked improvement in dissolution behavior for all DP ...
Munz Dominik - - 2013
A series of ortho-phenylene bridged palladium bis-NHC complexes has been synthesized. Complexes with imidazolium and benzimidazolium derived NHCs and methyl-/benzyl-wingtips are reported. Bis(benz)imidazoles with a doubly brominated ortho-phenylene bridge could be obtained by an electrophilic substitution reaction. The structure of the complexes could be confirmed by three solid-state structures. All ...
Deisenhammer Florian - - 2013
Editors' Note: In reference to Rudick and Miller's editorial, "Multiple sclerosis or multiple possibilities: The continuing problem of misdiagnosis," Dr. Deisenhammer calls attention to the importance of CSF oligoclonal band analysis in difficult diagnostic cases. The authors agree but point out reasons for caution. Drs. Kano et al. ask whether ...
Yanagida Satoshi - - 2013
Mammalian genomes encode numerous antisense non-coding RNAs, which are assumed to be involved in the regulation of the sense gene expression. However, the mechanisms of their action and involvement in the development of diseases have not been well elucidated. The ANA/BTG3 protein is an antiproliferative protein whose expression is downregulated ...
Maloney Alan - - 2013
The objective of this paper was to find and investigate the performance of the D optimal designs for three Poisson dose-response models. Phase II dose ranging studies are pivotal in the drug development program, being used to select dose(s) for phase III. Count data is encountered in a number of ...
Demirel Gamze - - 2013
Abstract Objective: To evaluate the efficacy of nasal intermittent mandatory ventilation (NIMV) in reducing the duration of respiratory distress compared with nasal continuous positive airway pressure (NCPAP) in transient tachypnea of the newborn (TTN). Patient and methods: Forty infants with a gestational age ≥37 weeks, and birth weight ≥2000 g ...
Kitahara Ken - - 2013
Electropharmacological effects of oseltamivir were studied in comparison with pilsicainide using halothane-anesthetized dogs (n = 4) and isolated left atrium of guinea pigs (n = 5). Oseltamivir (0.3, 3 and 30 mg/kg, i.v.) or pilsicainide (1 and 3 mg/kg, i.v.) was additionally administered to the dogs. The low dose of oseltamivir provided clinically relevant plasma concentrations ...
Durga Prasad Goli V M L - - 2013
We study here different regions in phase diagrams of the spin-1/2, spin-1 and spin-3/2 one-dimensional antiferromagnetic Heisenberg systems with frustration (next-nearest-neighbor interaction J(2)) and dimerization (δ). In particular, we analyze the behaviors of the bipartite entanglement entropy and fidelity at the gapless to gapped phase transitions and across the lines ...
Heegard Kelly D - - 2013
Adverse reactions during hemodialysis are extremely common and include a wide range of clinical presentations from mild to life threatening. We present a case of a 34 year old woman in the Burn Intensive Care Unit, who developed acute kidney injury requiring renal replacement therapy. She was placed on continuous ...
Onono Joshua Orungo - - 2013
This study analyzed the determinants for choice of animal health providers in a semiarid pastoral area with an aim of identifying specific attributes that could be targeted for intervention to enhance pastoralist access to quality veterinary services. The data were collected through administration of semi-structured questionnaires to 350 randomly selected ...
Burra Nicolas - - 2013
Attentional capture by salient distractors has been confirmed by the occurrence of an N2pc to the salient distractor. To clarify some failures to replicate this finding, we varied target predictability to induce different search modes. In the unpredictable target condition, the target shape varied randomly from trial to trial, favoring ...
Chiatti Carlos - - 2013
Objective: The aim of the analysis is to assess the impact of privately employed migrant care workers (MCWs) on the burden of Italian family members who care for a disabled older person. Methods: EUROFAMCARE is a one-year prospective survey carried out to provide evidence on the availability and use of ...
André Christelle Martine - - 2013
Three triterpene-caffeates have been isolated from skins of a russeted apple cultivar 'Merton Russet' and identified by LC-MS and NMR as betulinic acid-3-cis-caffeate, betulinic acid-3-trans-caffeate and oleanolic acid-3-trans-caffeate. Betulinic acid-3-trans-caffeate and oleanolic acid-3-trans-caffeate were also found in russeted pear skins. These compounds have not been previously reported in apples or ...
Jagminas Liudvikas - - 2013
QUESTION What are the relative efficacy and safety of procalcitonin (PCT)-guided initiation and discontinuation of antibiotic therapy compared with usual care in adults with acute respiratory infection (ARI)? REVIEW SCOPE Included studies compared PCT-based antibiotic therapy initiation or discontinuation strategies with a control group without knowledge of PCT level or ...
Xu Bing - - 2013
Sanitary sewage can create serious environmental problems if discharged directly into natural waters without appropriate treatment. This study showed that red light is the optimum light wavelength for growing microalgae Chlorella vulgaris in microalgae biological wastewater treatment systems, given a harvest time of 144 h. Only moderate light intensities (1,000, 1,500, ...
Vologni Valentina - - 2013
Microbial fuel cells (MFCs) have received attention as a promising renewable energy technology for waste treatment and energy recovery. We tested a submersible MFC with an innovative design capable of generating a stable voltage of 0.250 ± 0.008 V (with a fixed 470 Ω resistor) directly from primary sludge. In a polarization test, the ...
Colton Patricia A - - 2013
BACKGROUND: Depression and disturbed eating behavior (DEB) are more common in girls with type 1 diabetes (T1D) than in the general population, and may negatively affect metabolic control. OBJECTIVE: To examine the relationship among depression, DEB, and metabolic control in teenage girls with T1D. METHODS: Metabolic control, body mass index ...
Lee Soo Jung - - 2013
PURPOSE: The present study evaluated the predictive and prognostic impact of initial fluorine-18-fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) in patients with locally advanced rectal cancer treated with neoadjuvant concurrent chemoradiotherapy (CCRT). METHODS: Eighty-one consecutive patients with locally advanced rectal cancer (cT3-T4 N-/N+) treated with neoadjuvant CCRT were enrolled. The FDG-PET/CT parameters, including ...
Xu Peng - - 2013
This research was conducted to evaluate the design of hospital ultraviolet germicidal irradiation (UVGI) systems and to assess their effectiveness for inactivating airborne mycobacteria. A computational fluid dynamics (CFD) model was developed and tested by simulating previous experiments measuring the effectiveness of a lab-based UVGI system. Model testing showed reasonable ...
Bollero Daniele - - 2013
Wound dehiscence is a surgical complication caused by the application of opposing and distracting forces tending to pull apart the suture line. In recent years, a novel negative pressure surgical management system has been developed to prevent surgical wound complications. This system creates a closed environment that removes exudates and ...
Im Nam-Kyung - - 2013
6,4'-dihydroxy-7-methoxyflavanone (DMF) is a flavonoid isolated from Heartwood Dalbergia odorifera. It has been known that DMF has antioxidant, anti-inflammatory and neuroprotective effects. DMF, however, the efficacy of bone related diseases has not been reported. In this study, we determined DMF's efficacy on osteoclasts differentiation and function using in vitro bone ...
Taira Fumi - - 2013
Tumor lysis syndrome, a complication of anticancer chemotherapy, results from rapid lysis of malignant cells. We report tumor lysis syndrome in a patient treated with trastuzumab for metastatic breast carcinoma. A 69-year-old woman was diagnosed with multiple liver metastases 1 month after mastectomy. As her liver functions had deteriorated, chemotherapeutic agents ...
Oh Sun Min - - 2013
Dietary protein has a mixed effect on skeletal health and the effect may differ by amount or source of protein. The purpose of this study was to investigate dietary protein in relation to bone density and fat-free mass in rural Korean residents consuming relatively low protein diets. Between 2008 and ...
Chung Cheng-Shu - - 2013
Stem cell transplantation is one of the most promising yet enigmatic treatments for spinal cord injury (SCI), a common problem in dogs. As pre-differentiated mesenchymal stem cells (MSCs) can be expanded and differentiated into neurospheres in vitro, before being transplanted back, they may prove to be more beneficial for treating ...
Chin Jerome H - - 2013
There are an estimated 50 million people living with epilepsy (PLWE) worldwide.(1) In the United States and other high-income countries, PLWE are offered a wide range of advanced diagnostic and therapeutic services. In stark contrast, the vast majority of PLWE in poorer regions of the world receive no care and ...
Boland Michael V - - 2013
Glaucoma is an acquired degeneration of the optic nerve and a leading cause of blindness worldwide. Medical and surgical treatments that decrease intraocular pressure may prevent visual impairment and blindness. To compare the effectiveness of medical, laser, and surgical treatments in adults with open-angle glaucoma with regard to decreasing intraocular ...
Xu Haixia - - 2013
The 2-DE/MS-based proteomics approach was used to investigate the differences of porcine skeletal muscle, and ATP5B was identified as one differential expression protein. In the present study, ATP5B gene was further cloned by RT-PCR, the sequence was analyzed using the bioinformatics method, and the mRNA expression was detected by qRT-PCR. ...
Hafez Aly Mohamed - - 2013
Preparation of a nano porous gold surface by dealloying (etching) of 585 gold plate (58.5% Au, 30% Ag and 11.5% non nobel metals) was studied by applying acidic and thermal treatment of the gold pate. The gold plate surface was studied before and after the etching process using different analytical ...
Kaarme Johan - - 2013
AIM: The objective was to determine the prevalence of extended spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae in feces from healthy Swedish preschool children and to establish if transmission took place between children in preschools. METHODS: Diapers from children attending preschools in Uppsala city were collected during September to October 2010 and the ...
Simões Irina N - - 2013
Mesenchymal stem cells (MSC) have the potential to be applied in therapeutic settings due to their multilineage differentiation ability, immunomodulatory properties, as well as trophic activity. Umbilical cord matrix (UCM) represents a promising source of MSC for biomedical applications. The number of isolated cells per umbilical cord (UC) unit is ...
Anegawa Go - - 2013
PURPOSE: Perforated diverticulitis (PD) remains a serious acute abdominal condition. The aim of this study was to evaluate indications for emergency surgery in patients ≥80 years of age with PD. METHOD: Twenty patients ≥80 years of age and 28 younger patients who underwent emergency surgery for PD from January 2002 to December ...
McTrusty Alice D - - 2013
BACKGROUND: The purpose of this paper is to report a case of idiopathic isolated fovea plana showing asymmetry in the multifocal electroretinogram (mfERG). METHODS: We carried out optical coherence tomography (OCT) imaging, macular pigment density measurement, genetic testing and electrophysiological testing with visual evoked potentials and mfERGs on a young, ...
Zhang Zhi-Ming - - 2013
A polyoxometalate (POM)-based {Mn(IV)(2)Mn(III)(6)Mn(II)(4)} complex with single-molecule magnet (SMM) behaviour was prepared, exhibiting the largest known Mn nuclearity and the most Mn valence states in the POM-based SMM family.
Simsek Damla Gökşen - - 2013
Aim:Epidemiologic and clinical features of type 1 diabetes mellitus (T1DM) may show substantial differences among countries. The primary goal in the management of T1DM is to prevent micro- and macrovascular complications by achieving good glycemic control. The present study aimed to assess metabolic control, presence of concomitant autoimmune diseases, and ...
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