Search Results
Results 251 - 300 of 1922
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Bourjeily Ghada - - 2013
PURPOSE: Snoring is associated with adverse pregnancy outcomes including gestational hypertensive disorders, gestational diabetes, and Cesarean deliveries. The purpose of this study was to assess whether excessive daytime sleepiness (EDS) assessed by Epworth Sleepiness Scale (ESS) increases the risk of these complications further. METHODS: Following institutional review board approval and ...
Coote Paul - - 2013
We present a method for designing radio-frequency (RF) pulses for broadband or multi-band isotropic mixing at low power, suitable for protein NMR spectroscopy. These mixing pulses are designed analytically, rather than by numerical optimization, by repeatedly constructing new rotating frames of reference. We show how pulse parameters can be chosen ...
Braga Adelaide - - 2013
The main aim of this study was to compare different materials for Y. lipolytica immobilization that could be used in the production of γ-decalactone (a peach-like aroma) in order to prevent the toxic effect both of the substrate and the aroma upon the cells. Therefore, cells adsorption onto pieces of ...
Aydoğan Cemil - - 2013
Polymethacrylate based monolithic columns with weak cation exchange (WCX) properties were synthesized in fused silica capillary columns by capillary electrochromatography. Monolithic columns were prepared by in situ copolymerization of butyl methacrylate, ethylene dimethacrylate and N-methacryloyl-l-glutamic acid (MAGA) in a binary porogenic solvent composed of N,N-dimethyl formamide and phosphate buffer. The ...
Sande Ragnar K - - 2013
OBJECTIVE: To test the hypothesis that clinically relevant vessels can be visualized and interrogated with Doppler recording during the second half of pregnancy at an output energy below the currently advocated limits without loss of information. DESIGN: Observational cross-sectional study. SETTING: Tertiary fetal medicine center. SAMPLE: Based on a power ...
Spagnuolo Maria Stefania - - 2013
Apolipoprotein A-I (ApoA-I) is the main protein component of the high density lipoproteins and it plays an important role in the reverse cholesterol transport. In particular, it stimulates cholesterol efflux from peripheral cells toward liver and activates the enzyme lecithin-cholesterol acyltransferase (LCAT). Haptoglobin (Hpt), a plasma α(2) -glycoprotein belonging to ...
Pedro-Roig Laia - - 2013
In this work we report for the first time a post-translational modification of PII homologues from the Archaea Domain. Haloferax mediterranei is the first haloarchaea whose PII proteins have been studied, it possesses two of them (GlnK(1) and GlnK(2) ), both encoded adjacent to a gene for the ammonia transporter ...
Misawa Kiyoshi - - 2013
AIM: The aim of this study was to define TAC1 and TACR1 methylation profiles for head and neck squamous cell carcinoma (HNSCC) tumors at diagnosis and follow-up and to evaluate their prognostic significance and value as a biomarker of recurrence. MATERIALS AND METHODS: TAC1 and TACR1 expression was measured in ...
Hoffmann Kathryn - - 2013
OBJECTIVE: The aim of this study was to analyse the frequency of C-reactive protein (CRP) rapid test use by general practitioners (GPs), the role of the test in the antibiotic treatment decisions and the efficacy of the test in a primary care setting, with special emphasis on the redemption rate ...
Bomba Monica - - 2013
ABSTRACT: BACKGROUND: Anorexia nervosa commonly arises during adolescence and is associated with more than one medical morbidity. Abnormalities in brain structure (defined as "pseudoatrophy") are common in adolescents with anorexia nervosa; however, their correlations with endocrinological profiles and clinical parameters are still unclear. In particular, no study has described the ...
Banin Luciana Burgugi - - 2013
The present study aims to understand the relation between religious beliefs, physicians' behavior and patients' opinions regarding "Spirituality, religiosity and health (S/R)" issues, and what makes a patient more prone to accept a physician to address his/her spiritual issues. A cross-sectional study was carried out in outpatients from a tertiary ...
Wittink Marsha N - - 2013
BACKGROUND: While 'personalized medicine' commonly refers to genetic markers or profiles associated with pharmacological treatment response, tailoring treatments to patient preferences and values is equally important. OBJECTIVE: To describe and demonstrate a method to develop 'values markers,' or profiles based on the relative importance of attributes of depression treatment. STUDY ...
Beers Erna - - 2013
BACKGROUND: Historically, older patients have been frequently excluded from clinical trials. This has a knock-on effect on the availability of relevant information from trials for health-care professionals prescribing medicines to older individuals in daily clinical practice. OBJECTIVE: To investigate the availability of information relevant to appropriate prescribing for older people ...
Shiraishi Takeshi - - 2013
PURPOSE: Chemoradiation therapy (CRT) is recommended as standard care for stage III non-small cell lung cancer (NSCLC), but some patients experience local recurrence after the treatment. Surgical resection after CRT involves high surgical risk, but is expected to increase the curability. This study was performed to investigate the impact of ...
Billè Andrea - - 2013
We present a case of a 60-year-old woman with a positive fluorodeoxyglucose integrated positron emission tomography and computed tomography (PET/TC) mammary chain lymphadenopathy and carcinoid tumor of the left lower lobe who had a previous bilateral mastectomy and breast reconstruction for breast cancer. She underwent a right muscle sparing mini-thoracotomy ...
Zhou T - - 2013
(75)As nuclear magnetic resonance (NMR) measurements carried out on underdoped, non-superconducting Ca(10)(Pt(3)As(8))(Fe(2)As(2))(5) reveal physical properties that are similar but not identical to 122 superconductor parent compounds such as BaFe(2)As(2). Results from the single crystal study indicate a phase transition to an antiferromagnetic (AF) state on cooling through T ∼ 100 K, albeit nonuniformly. Specifically, the ...
Deisenhammer Florian - - 2013
Editors' Note: In reference to Rudick and Miller's editorial, "Multiple sclerosis or multiple possibilities: The continuing problem of misdiagnosis," Dr. Deisenhammer calls attention to the importance of CSF oligoclonal band analysis in difficult diagnostic cases. The authors agree but point out reasons for caution. Drs. Kano et al. ask whether ...
Yanagida Satoshi - - 2013
Mammalian genomes encode numerous antisense non-coding RNAs, which are assumed to be involved in the regulation of the sense gene expression. However, the mechanisms of their action and involvement in the development of diseases have not been well elucidated. The ANA/BTG3 protein is an antiproliferative protein whose expression is downregulated ...
Maloney Alan - - 2013
The objective of this paper was to find and investigate the performance of the D optimal designs for three Poisson dose-response models. Phase II dose ranging studies are pivotal in the drug development program, being used to select dose(s) for phase III. Count data is encountered in a number of ...
Demirel Gamze - - 2013
Abstract Objective: To evaluate the efficacy of nasal intermittent mandatory ventilation (NIMV) in reducing the duration of respiratory distress compared with nasal continuous positive airway pressure (NCPAP) in transient tachypnea of the newborn (TTN). Patient and methods: Forty infants with a gestational age ≥37 weeks, and birth weight ≥2000 g ...
Kitahara Ken - - 2013
Electropharmacological effects of oseltamivir were studied in comparison with pilsicainide using halothane-anesthetized dogs (n = 4) and isolated left atrium of guinea pigs (n = 5). Oseltamivir (0.3, 3 and 30 mg/kg, i.v.) or pilsicainide (1 and 3 mg/kg, i.v.) was additionally administered to the dogs. The low dose of oseltamivir provided clinically relevant plasma concentrations ...
Durga Prasad Goli V M L - - 2013
We study here different regions in phase diagrams of the spin-1/2, spin-1 and spin-3/2 one-dimensional antiferromagnetic Heisenberg systems with frustration (next-nearest-neighbor interaction J(2)) and dimerization (δ). In particular, we analyze the behaviors of the bipartite entanglement entropy and fidelity at the gapless to gapped phase transitions and across the lines ...
Heegard Kelly D - - 2013
Adverse reactions during hemodialysis are extremely common and include a wide range of clinical presentations from mild to life threatening. We present a case of a 34 year old woman in the Burn Intensive Care Unit, who developed acute kidney injury requiring renal replacement therapy. She was placed on continuous ...
Onono Joshua Orungo - - 2013
This study analyzed the determinants for choice of animal health providers in a semiarid pastoral area with an aim of identifying specific attributes that could be targeted for intervention to enhance pastoralist access to quality veterinary services. The data were collected through administration of semi-structured questionnaires to 350 randomly selected ...
Burra Nicolas - - 2013
Attentional capture by salient distractors has been confirmed by the occurrence of an N2pc to the salient distractor. To clarify some failures to replicate this finding, we varied target predictability to induce different search modes. In the unpredictable target condition, the target shape varied randomly from trial to trial, favoring ...
Chiatti Carlos - - 2013
Objective: The aim of the analysis is to assess the impact of privately employed migrant care workers (MCWs) on the burden of Italian family members who care for a disabled older person. Methods: EUROFAMCARE is a one-year prospective survey carried out to provide evidence on the availability and use of ...
André Christelle Martine - - 2013
Three triterpene-caffeates have been isolated from skins of a russeted apple cultivar 'Merton Russet' and identified by LC-MS and NMR as betulinic acid-3-cis-caffeate, betulinic acid-3-trans-caffeate and oleanolic acid-3-trans-caffeate. Betulinic acid-3-trans-caffeate and oleanolic acid-3-trans-caffeate were also found in russeted pear skins. These compounds have not been previously reported in apples or ...
De Brakeleer Sylvia - - 2013
Pathogenic Alu element insertions are rarely reported while their occurrence is expected to be much higher. Alu containing alleles are usually out-competed during the PCR process and consequently undetectable with the classical screening methods. However, with the introduction of the Next Generation Sequencing technology in the diagnostic field new opportunities ...
El-Houseini Motawa E - - 2013
Abstracts: Curcumin and Taurine are natural products that have been used in this purpose to evaluate their therapeutic effect on the myeloid leukemic cells propagated in vitro. Sixty myeloid leukemia patients and thirty healthy volunteers were enrolled in the study. All patients groups were admitted to the medical oncology department ...
Dirksen C - - 2013
Objective:To identify factors contributing to the variation in weight loss after Roux-en-Y gastric bypass (RYGB).Design:Cross-sectional study of patients with good (excess body mass index lost (EBL) >60%) and poor weight loss response (EBL <50%) >12 months after RYGB and a lean control group matched for age and gender.Materials and methods:Sixteen ...
Zheng Jiaxin - - 2013
Radio-frequency application of graphene transistors is attracting much recent attention due to the high carrier mobility of graphene. The measured intrinsic cut-off frequency (f(T)) of graphene transistor generally increases with the reduced gate length (L(gate)) till L(gate) = 40 nm, and the maximum measured f(T) has reached 300 GHz. Using ab initio ...
Wang Helen H HH Division of Gastroenterology and Hepatology, Department of Internal Medicine, Saint Louis University School of Medicine, St. Louis, MO 63104, - - 2013
Cholesterol cholelithiasis is a multifactorial disease influenced by a complex interaction of genetic and environmental factors and represents a failure of biliary cholesterol homoeostasis in which the physical-chemical balance of cholesterol solubility in bile is disturbed. The primary pathophysiologic event is persistent hepatic hypersecretion of biliary cholesterol, which has both ...
Ai Li-Sha - - 2013
Osteolytic bone diseases are a prominent feature of multiple myeloma (MM), resulting from aberrant osteoclastic bone resorption that is uncoupled from osteoblastic bone formation. Myeloma stimulates osteoclastogenesis, which is largely dependent on an increase in receptor activator of NF-κB ligand (RANKL) and a decrease in osteoprotegerin (OPG) within the bone ...
Roux Kyle J KJ Children's Health Research Center, Sanford Research/USD, North 60th St. East, Sioux Falls, SD, 57104, USA, - - 2013
Various methods have been established for the purpose of identifying and characterizing protein-protein interactions (PPIs). This diverse toolbox provides researchers with options to overcome challenges specific to the nature of the proteins under investigation. Among these techniques is a category based on proximity-dependent labeling of proteins in living cells. These ...
Korkmaz Hüseyin Anıl - - 2013
Turner syndrome (TS) is a genetic disorder that affects development in females and is characterized by the complete or partial absence of the second sex chromosome, or monosomy X. TS is associated with abnormalities in lymphatic and skeletal development, in growth, and in gonadal function. Cardiac and renal malformations and ...
Zeevi David A - - 2013
Long-range PCR is generally employed for the analysis of disease-causing mutations in genes with homologous pseudogene copies. However, long-range PCR is challenging when performed on single cells, as in PGD of monogenic disorders. PGD on single cells requires concurrent analysis of a mutation together with multiple linked polymorphic markers from ...
Miyazaki Nozomu - - 2013
The aim of the present study was to clarify the involvement of P-glycoprotein (P-gp) or organic anion transporting polypeptide (Oatp) 1a5 in the pharmacokinetics of nadolol (NDL), a non-metabolized hydrophilic β-adrenoceptor blocker, in rats. Pretreatment of itraconazole (ICZ, P-gp inhibitor, 50 mg/kg) for 30 min before oral administration of NDL ...
Arcelus Juan I - - 2013
QUESTION Does a risk stratification model predict venous thromboembolism (VTE) events requiring treatment after outpatient surgery? METHODS DESIGN Registry-based cohort study for derivation and validation of a risk prediction index. SETTING American College of Surgeons' National Surgical Quality Improvement Program Participant Use File (ACS-NSQIP) database. PATIENTS 259 231 patients who had ...
Bai Xiaojuan - - 2013
ABSTRACT: ZnO1-x/graphene hybrid photocatalyst was prepared via a facile in-situ reduction of graphene oxide and ZnO1-x surface defect oxide. The hybrid photocatlayst showed enhanced photocatalytic activity for the photodegradation of methylene blue. The photocorrosion of ZnO1-x was successfully inhibited by graphene hybridation. ZnO1-x/graphene hybrid photocatalyst with 1.2 wt% graphene showed ...
Bessho Fumio - - 2013
Lymphoblasts of acute lymphoblastic leukemia origin reappeared in a male patient 34 years after the initial diagnosis. Comparison of DNA profiles of the initial and reappeared lymphoblasts revealed a partially identical sequence, indicating the possibility that these lymphoblasts may have been present as preleukemic stem cells at the time of diagnosis ...
Wang Yuling - - 2013
SERS labels are a new class of nanotags for optical detection based on Raman scattering. Central advantages include their spectral multiplexing capacity due to the small line width of vibrational Raman bands, quantification based on spectral intensities, high photostability, minimization of autofluorescence from biological specimens via red to near-infrared (NIR) ...
Ishikawa Takeshi - - 2013
A core challenge in administering immune-based treatments for cancer is the establishment of easily accessible immunological assays that can predict patients' clinical responses to immunotherapy. In this study, our aim was to predict the therapeutic effects of adoptive T-cell therapy in patients with advanced pancreatic cancer. To do this, we ...
Mette C - - 2013
OBJECTIVE: To date, the impact of the neurotransmitter serotonin (5-HT) on different neuropsychological functions in adults with attention deficit hyperactivity disorder (ADHD) is underinvestigated. We aimed to examine the effects of acute tryptophan depletion (ATD) and the resulting reduction in central nervous 5-HT synthesis on target/non-target discrimination ability and sustained ...
Medraño-Fernandez Iria - - 2013
Phagocytosis mediated by the complement receptor CR3 (also known as integrin α(M)ß(2) or Mac-1) is regulated by the recruitment of talin to the cytoplasmic tail of the ß(2) integrin subunit. Talin recruitment to this integrin is dependent on Rap1 activation. However, the mechanism by which Rap1 regulates this event and ...
Launiainen Samuli - - 2013
The water footprint by the Water Footprint Network (WF) is an ambitious tool for measuring human appropriation and promoting sustainable use of fresh water. Using recent case studies and examples from water-abundant Fennoscandia, we consider whether it is an appropriate tool for evaluating the water use of forestry and forest-based ...
Zheng Li-Qiang - - 2013
Tuberous sclerosis is a genetic multisystem disorder characterized by widespread hamartomas in several organs. Clinically, more than 90% of affected patients have skin lesions including facial angiofibromas, periungual fibromas, hypomelanotic macule, etc. Periungual fibroma is one of the major diagnostic criteria of tuberous sclerosis and has the same pathology (angiofibroma) ...
Uchiyama Masanobu - - 2013
A practical high-performance liquid chromatography using a Cosmosil HILIC column and UV detection was developed for determining the concentrations of cytosine arabinoside (Ara-C) and uracil arabinoside (Ara-U), which is a major metabolite of Ara-C, in human plasma. This method was used to determine the plasma concentrations of Ara-C and Ara-U ...
García-Moya I - - 2013
The aim of this study was to examine the role of school variables and sense of coherence (SOC) in the explanation of health. For this purpose, data were collected from a representative sample of adolescents, aged 13 to 18 years, selected for the Health Behavior in School-aged Children survey in Spain. ...
Charlton Rebecca A RA Department of Psychiatry, University of Illinois at Chicago, Chicago, IL, - - 2013
Major depressive disorder (MDD) is prevalent across the lifespan, but relatively little is known about how age of illness onset impacts the cognitive and affective presentation of MDD. We explore depressive symptoms and cognition in 70 adults (30-89 years old) with MDD. Participants were divided into three groups on the ...
Neyzi Olcay - - 2013
A historical review of anthropometric studies conducted on Turkish children and adults is presented. In view of observed differences in growth status between children of different societies, the need for local reference standards and the methodology to be used for such studies have been stressed. The importance of local studies ...
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