Search Results
Results 201 - 250 of 1922
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Han Tao - - 2013
Retinol-binding protein 4 (RBP4) is closely associated with a variety of abnormal glycolipid metabolism diseases such as insulin resistance, obesity, diabetes mellitus, and metabolic syndrome. Part 1 Twenty-four male C57/B6 mice were randomly divided into a normal control group (group C, n = 8), a gallstone group (group G, n = 8), and a ...
Khalid Umair - - 2013
QUESTION In patients with systolic heart failure (HF), what are the effects of a restricted-sodium diet compared with a normal-sodium diet? REVIEW SCOPE Included studies compared dietary interventions that restricted salt intake or advised reduced salt intake with placebo or control diet or no intervention in patients ≥ 18 years of ...
Liu Haizhou - - 2013
A moderately halophilic actinomycetes strain, designated as WH26, was isolated from Weihai Solar Saltern in China. The identification of the strain WH26 was performed by its morphological characteristics, physiological and biochemical tests as well as phylogenetic analysis based on 16S rRNA sequence comparison. The results showed that the nucleotide sequence ...
Wikström Shemer E - - 2013
OBJECTIVE: To determine the risk for adverse pregnancy and fetal outcomes in intrahepatic cholestasis of pregnancy (ICP). DESIGN: Population-based cohort study. SETTING: Swedish Medical Birth Register (MBR) 1997-2009. POPULATION: A total of 1 213 668 singleton deliveries. METHODS: Linkage of Hospital Discharge Register for exposure (ICP; n = 5477) with MBR for covariates. MAIN ...
Kulkarni Hemant H Department of Genetics, Texas Biomedical Research Institute, San Antonio, TX 78227, USA. - - 2013
The role of v-ATPases in cancer biology is being increasingly recognized. Yeast studies indicate that the tyrosine kinase inhibitor imatinib may interact with the v-ATPase genes and alter the course of cancer progression. Data from humans in this regard are lacking. We constructed 55 lymphoblastoid cell lines from pedigreed, cancer-free ...
Gutiérrez-Kobeh Laila - - 2013
Macrophages (Mφ) and dendritic cells are the major target cell populations of the obligate intracellular parasite Leishmania. Inhibition of host cell apoptosis is a strategy employed by multiple pathogens to ensure their survival in the infected cell. Leishmania promastigotes have been shown to protect Mφ, neutrophils, and dendritic cells from ...
Nicholson George T - - 2013
A newborn infant with obstructed supracardiac total anomalous pulmonary venous return underwent emergent surgical correction on day of life 0. A surgically placed transthoracic pulmonary artery catheter was used to monitor pulmonary artery pressure and removed on post-operative day 3. Following acute deterioration in respiratory status requiring reintubation, echocardiographic assessment ...
Swahn Fredrik - - 2013
OBJECTIVES:The aim of this study was to investigate if intraoperative rendezvous cannulation reduces the risk of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) because there is no universal consensus on the optimal treatment of common bile duct stones.METHODS:We performed a nationwide case-control study, nested within the cohort of ERCP procedures reported ...
Rebonatto Marcelo Trindade - - 2013
The use of electromedical equipment (EME) throughout the years has brought benefits in the aid of diagnosis and therapies as well as in surgical interventions. However, the equipment may fail and can cause health hazards, for example, the passing of a small but dangerous electric current through the patient (microshock). ...
Haanstra Jasmijn F - - 2013
Lynch syndrome, or hereditary nonpolyposis colorectal cancer (HNPCC), is the most common hereditary condition predisposing for colorectal cancer. International guidelines recommend surveillance of the colorectum by colonoscopy every 1-2 years starting at the age of 20-25 years. This has been shown to reduce the incidence of, and mortality due to colorectal cancer. ...
Krilis Matthew - - 2013
Amyl nitrite 'poppers' are recreational drugs, which are a potent source of nitric oxide. The use of 'poppers' can cause psychoactive stimulation, reduced blood pressure, tachycardia and involuntary muscle relaxation. Their use is becoming increasingly common around the world, including approximately 60% of Australia's male homosexual community. We report the ...
Bueschel Philip - - 2013
BACKGROUND: Aneurysms of visceral arteries are rare, but in case of rupture, they are potentially life threatening. In addition, there is a broad spectrum of the anatomic variability for the arterial supply of the liver. METHODS: Based on a real but very rare clinical case, including its diagnostic management and ...
Stoehr Andrew M - - 2013
ABSTRACT: BACKGROUND: Little is currently known about wing pattern development in the butterfly family Pieridae, which consists mostly of black melanized elements on white or yellow/orange backgrounds. A single transcription factor, Spalt (Sal), has been previously associated with the development of some pattern elements in Pieris rapae, but it is ...
Stepankova Veronika - - 2013
Haloalkane dehalogenases are microbial enzymes with a wide range of biotechnological applications. The use of organic co-solvents to solubilize their hydrophobic substrates is often necessary. In order to choose the most compatible co-solvent, the effects of fourteen co-solvents on activity, stability and enantioselectivity of three model enzymes, DbjA, DhaA and ...
Liang Lu - - 2013
In the present study, the main natural estrogen-agonist/antagonist from Pigeonpea roots was studied by the estrogen receptor α-dependent signaling pathway in human prostate cancer cell. First, the natural products with estrogenic activity in Pigeonpea roots were screened by pER8-GFP transgenic Arabidopsis, and cajanol (5-hydroxy-3-(4-hydroxy-2-methoxyphenyl)-7-methoxychroman-4-one) was confirmed as the active compound. ...
Holm Henriette Veiby - - 2013
BACKGROUND: The relationship between urological and psychosocial variables, and generic quality of life in patients operated on for post-prostatectomy incontinence has hardly been studied, and our aim was to investigate this relationship. METHODS: Patients who had an artificial urinary sphincter AMS800 (n = 100) implanted between January 2002 and June 2010 were ...
Diana Donatella - - 2013
Angiogenesis is mainly regulated by the vascular endothelial growth factor (VEGF), a mitogen specific for endothelial cells, which binds two tyrosine kinase receptors, VEGFR1 and VEGFR2, on the surface of endothelial cells. Molecules targeting VEGF receptors are attractive to pharmacologically treat diseases associated with angiogenesis or to be used as ...
Stacker Steven A - - 2013
The vascular endothelial growth factor (VEGF) family of soluble protein growth factors consists of key mediators of angiogenesis and lymphangiogenesis in the context of tumor biology. The members of the family, VEGF-A (also known as VEGF), VEGF-B, VEGF-C, VEGF-D and placenta growth factor (PlGF), play important roles in vascular biology ...
Avalos Lyndsay A - - 2013
To evaluate the prevalence, trends, timing and duration of exposure to antiviral medications during pregnancy within a US cohort of pregnant women and to evaluate the proportion of deliveries with a viral infection diagnosis among women given antiviral medication during pregnancy. Live-born deliveries between 2001 and 2007, to women aged ...
Miyake Mototaka - - 2013
OBJECTIVE: To compare the efficacy of computer-aided detection (CAD) for computed tomographic colonography (CTC) when employed as either primary-reader or second-reader paradigms in a low-prevalence screening population. METHODS: Ninety screening patients underwent same-day CTC and colonoscopy. Four readers prospectively interpreted all CTC data sets using a second-reader paradigm (unassisted interpretation ...
Kranenburg H C - - 2013
Both spondylosis and diffuse idiopathic skeletal hyperostosis (DISH) are prevalent in humans and are considered distinct entities. Nowadays, the term spondylosis is in the biomedical literature mostly used when also degenerative disc disease is present. In companion animals, many reports on spondylosis, often without intervertebral disc degeneration, are described. The ...
Gilbert-López Bienvenida - - 2013
In this work, the combined use of desorption by a continuous wave near infrared diode laser and ionization by a dielectric barrier discharge-based probe (laser desorption dielectric barrier discharge ionization mass spectrometry (LD-DBDI-MS)) is presented as an ambient ionization method for the mass spectrometric detection of non-volatile chemicals on surfaces. ...
Barken Sidsel S - - 2013
OBJECTIVE: To measure adherence to annual follow-up among women treated for cervical intraepithelial neoplasia. DESIGN: Prospective, population-based, register study. SETTING: Denmark, 1996-2007. POPULATION: All women treated for cervical intraepithelial neoplasia with conization. METHODS: Treated women were routinely recommended to have follow-up with annual smears for at least five years. MAIN ...
Gonnerman Matthew C - - 2013
Methanosarcina barkeri is an Archaeon that produces methane anaerobically as the primary byproduct of its metabolism. M. barkeri can utilize several substrates for ATP and biomass production including methanol, acetate, methyl amines and a combination of hydrogen and carbon dioxide. In 2006, a metabolic reconstruction of M. barkeri, iAF692, was ...
Castiglione Morelli Maria Antonietta - - 2013
The interaction between cisplatin and an 18-residue CCHC zinc finger motif derived from a retroviral nucleocapsid protein (PyrZf18) has been studied using UV-visible, CD and (1) H NMR spectroscopies and ESI-MS spectrometry. Cisplatin irreversibly blocks the cysteine zinc binding groups in the free peptide and is able to slowly eject ...
Herbers Claudia R - - 2013
A detailed understanding of the adsorption of small molecules or macromolecules to a materials surface is of importance, for example, in the context of material and biomaterial research. Classical atomistic simulations in principle provide microscopic insight in the complex entropic and enthalpic interplay at the interface. However, an application of ...
Liu Da-Yong - - 2013
We investigate the electronic and magnetic properties of K(x)Fe(2-y)Se(2) materials at different band fillings utilizing the multi-orbital Kotliar-Ruckenstein slave boson mean-field approach. We find that the ground state of KFe(2)Se(2) is a paramagnetic (PM) bad metal with intermediate correlation, in contrast with the previous antiferromagnetic (AFM) results obtained by the ...
Moser Gabriele - - 2013
OBJECTIVES:Gut-directed hypnotherapy (GHT) in individual sessions is highly effective in the treatment of irritable bowel syndrome (IBS). This study aimed to assess the long-term effect of GHT in group sessions for refractory IBS.METHODS:A total of 164 patients with IBS (Rome-III-criteria) were screened, and 100 refractory to usual treatment were randomized ...
Ringe Emilie - - 2013
Interest in nanotechnology is driven by the unique and novel properties of nanoscale materials such as the strong interaction of metal particles with light, caused by localized surface plasmon resonances (LSPRs). In this perspective article we review and discuss prominent advantages and advances in single particle studies of plasmonic nanostructures. ...
Cheung Angela M - - 2013
QUESTION In recently postmenopausal women, what are the long-term effects of hormone replacement therapy (HRT) on cardiovascular (CV) outcomes? METHODS DESIGN Randomized controlled trial (RCT) (Danish Osteoporosis Prevention Study [DOPS]). ClinicalTrials.gov NCT00252408. ALLOCATION Unclear allocation concealment.* BLINDING Blinded* (outcome assessors). FOLLOW-UP PERIOD 10 years of therapy and 16 years follow-up ...
Lin Bai-Xue - - 2013
N-Acetyl-D-neuraminic acid (Neu5Ac) has attracted considerable interest due to its promising potential applications in medicine. Significant efforts have been made in whole-cell biocatalyst for Neu5Ac production, but the processes often result in suboptimal performance due to poor expression of enzymes, imbalances of pathway components, disturbance of competing pathways, and barriers ...
Fuss Ivan J - - 2013
PURPOSE: Patients with Common Variable Immunodeficiency (CVID) are subject to the development of a liver disease syndrome known as nodular regenerative hyperplasia (NRH). The purpose of this study was to define the characteristics and course of this complication of CVID. METHODS: CVID patients were evaluated by retrospective and prospective clinical ...
Ali Zarqa - - 2013
INTRODUCTION: The prevalence of bronchopulmonary dysplasia (BPD), one of the most frequently occurring complications following preterm birth, is increasing due to increased survival of preterm infants. METHODS: Systematic literature review. CONCLUSION: The etiology is multifactorial, with prematurity being a prerequisite for the development of BPD. Over time, there have been ...
Liu J - - 2013
A new immobilization strategy of catalases on natural fibers was reported in this paper. Catalase (CAT) from Bacillus subtilis was assembled into multiple layers together with poly(diallyldimethylammonium chloride) (PDDA) on wool fabrics via layer-by-layer (LBL) electrostatic self-assembly deposition. The mechanism and structural evaluation of LBL electrostatic self-assembly were studied in ...
Shimokawa Tetsuya - - 2013
Prosaposin (PSAP) is as a trophic factor and an activator protein for sphingolipid hydrolase in lysosomes. We generated a specific antibody to PSAP and examined the spatiotemporal distribution of PSAP-immunoreactive (PSAP-IR) cells in the lymphatic tissues of Wistar rats. Immunoblots of tissue homogenates separated electrophoretically showed a single band for ...
Nikolaidis Christos - - 2013
The 'Agios Philippos' lead-zinc mine in the Kirki region (NE Greece) is now closed, but its legacy of heavy metal contamination remains at the site. At present, management of the contaminated land is of major concern. The area is in a reclamation process and requires immediate remediation action, whereas human ...
Eloot Liesbeth - - 2013
OBJECTIVES: The purpose of this study was to assess patient-specific organ doses and cancer risk with 3D-rotational acquisitions versus the current standard of multiple single-plane coronary angiography. BACKGROUND: Catheter-based coronary angiography remains one of the most commonly performed diagnostic invasive procedures delivering a relatively high radiation dose to the patient. ...
Thoma Daniel S - - 2013
OBJECTIVE: To compare the clinical and radiographic outcomes of implants and implant-supported reconstructions using a 1-piece (STM) and a 2-piece (BRA) dental implant system. MATERIAL AND METHODS: Sixty patients were randomly assigned to receive STM or BRA implants. The implants restored with fixed or removable prostheses. Baseline measurements (day of ...
Kim Hak-Joon - - 2013
A novel positive-polarity electrostatic precipitator (ESP) was developed using an ionization stage (0.4 x 0.4 x 0.14 m(3) ) with 16 carbon fiber ionizers in each channel and a collection stage (0.4 x 0.4 x 0.21 m(3) ) with parallel metallic plates. The single-pass collection efficiency and clean air delivery ...
Aissat Abdel - - 2013
With the increased number of identified nucleotide sequence variations in genes, the current challenge is to classify them as disease-causing or neutral. These variants of unknown clinical significance can alter multiple processes, from gene transcription to RNA splicing or protein function. Using an approach combining several in silico tools, we ...
Ebata Shigeto - - 2013
BACKGROUND: Minimally invasive posterior spinal endoscopic surgery has increased in popularity. However, a steep learning curve may result in a high frequency of complications. Additionally, device failure may occur during routine use. We retrospectively investigated the incidence of such safety issues in a population of patients undergoing endoscopic spinal surgery ...
Shimizu Takao - - 2013
An increase of the Curie temperature, T(C), was demonstrated for BaTiO(3) (BTO) epitaxial thin films grown by a pulsed laser deposition technique on (001) and (110) SrTiO(3) (STO) substrates. The T(C) values for the BTO films on (001) and (110) STO were determined, from the temperature dependence of the lattice ...
Vather Ryash - - 2013
BACKGROUND: Prolonged post-operative ileus (PPOI) occurs in up to 25% of patients following major elective abdominal surgery. It is associated with a higher risk of developing post-operative complications, prolongs hospital stay and confers a significant financial load on health-care institutions. Literature outlining best-practice management strategies for PPOI is nebulous. The ...
D'Hulst Gommaar - - 2013
Hypoxia-induced muscle wasting has been observed in several environmental and pathological conditions. However, the molecular mechanisms behind this loss of muscle mass are far from being completely elucidated, certainly in vivo. When studying the regulation of muscle mass by environmental hypoxia, many confounding factors have to be taken into account, ...
Avilés-Nieto Jonathan N - - 2013
The objective of this experiment was to evaluate the effect of supplementing increasing levels of Gliricidia sepium hay (GS) with different levels of inclusion of Buffel grass (BG) hay on digestibility by hair sheep lambs (2.5 to 3.5 months of age). Eight male lambs were used in a replicated 4 × 4 Latin ...
Karaman Rafik - - 2013
DFT calculations for the acid-catalyzed hydrolysis of several maleamic acid amide derivatives revealed that the reaction rate-limiting step is determined on the nature of the amine leaving group. Further, it was established that when the amine leaving group was a secondary amine, acyclovir or cefuroxime moiety the tetrahedral intermediate formation ...
Tsukahara Satoshi - - 2013
The present study proposed a novel microscope method for the determination of the surface tension of liquids through measurements of the forced oscillation of the small surface, which was induced with a rod electrode by applying an alternating current (ac) voltage. The electrode bottom was placed 200 μm above the ...
Fairfield Kathleen M - - 2013
QUESTION Does long-term use of multivitamin supplements reduce risk for major cardiovascular (CV) events in men? METHODS DESIGN Randomized, placebo-controlled, factorial trial (Physicians' Health Study II). ClinicalTrials.gov NCT00270647. ALLOCATION {Concealed}*.† BLINDING Blinded† (participants, {data collectors}*, and endpoint committee). FOLLOW-UP PERIOD Median 11.2 years. SETTING USA. PARTICIPANTS 14 641 male physicians ≥ 50 ...
Ramani Pramila - - 2013
Angiogenin (ANG) is a potent angiogenic factor that is up-regulated by hypoxia. ANG expression is well documented in normal tissues and in common tumours, but its expression has not been reported in the normal human kidney or in Wilms' tumours (WT). We examined ANG expression in WTs, human fetal kidney ...
Chen Hung-Yuan - - 2013
BACKGROUND AND OBJECTIVES: Fetuin A, a predictor of mortality in dialysis patients, is associated with vascular calcification and atherosclerosis in haemodialysis (HD) patients. Whether it predicts stroke remains unknown. This study aimed to investigate the association between fetuin A and incident stoke in maintenance HD patients. DESIGN, SETTING, PARTICIPANTS AND ...
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