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Selig H F - - 2013
BACKGROUND: Few data exist on the epidemiological characteristics of thermal injuries in prehospital emergency care, especially in the context of air rescue. Therefore, this study aimed to analyze the epidemiology of pediatric and adult thermal injuries in the helicopter emergency medical service (HEMS) run by the Austrian automobile motorcycle touring ...
Veits L - - 2013
Lymphocytic esophagitis is a rare, ill-defined inflammatory disease of the esophagus and is characterized by an increased number of intraepithelial lymphocytes. Up to now no distinct clinical symptom or endoscopic finding could be linked to histopathological changes. Hence lymphocytic esophagitis remains a diagnosis by exclusion after ruling out other possible ...
Aaron Shawn D - - 2013
QUESTION In adults with chronic obstructive pulmonary disease (COPD), how effective are combined inhaled corticosteroid (ICS) plus long-acting β2-agonist (LABA) preparations compared with LABAs alone? REVIEW SCOPE Included studies compared combined ICS plus LABA (ICS/LABA) inhalers (fluticasone and salmeterol [FPS] or budesonide and formoterol [BDF]) with the same LABA alone ...
Yan Hanfei - - 2013
For scanning x-ray microscopy, many attempts have been made to image the phase contrast based on a concept of the beam being deflected by a specimen, the so-called differential phase contrast imaging (DPC). Despite the successful demonstration in a number of representative cases at moderate spatial resolutions, these methods suffer ...
Liu Wu - - 2013
In this work, sub-microlitre droplets were generated by gravity and electrostatic attraction using a capillary tube. The parameters affecting the sizes and frequency of the droplets were investigated. The volume of droplets could be controlled in the range from 0.7 μL to 2.4 μL and the time interval from 15 ...
Marinho M A T - - 2013
The internal transcribed spacer 2 (ITS2) of the eukaryotic ribosomal DNA (rDNA) cluster plays an essential role in processing of the ribosomal RNA, which is primarily accomplished by the secondary structures acquired by the molecule after transcription. Two possible structural conformation models have been proposed for the ITS2 region, the ...
Westberg Marianne - - 2013
Prosthetic joint infection (PJI) remains a devastating complication of arthroplasty. Today, most displaced femoral neck fractures in the elderly are treated with arthroplasty. We estimated the incidence of and risk factors for PJI in primary arthroplasty after femoral neck fracture. Patients admitted for a femoral neck fracture in 2008 and ...
Li Xiufeng - - 2013
Measurements of blood flow in the human hippocampus are complicated by its relatively small size, unusual anatomy and patterns of blood supply. Only a handful of arterial spin labeling (ASL) MRI articles have reported regional cerebral blood flow (rCBF) values for the human hippocampus. Numerous reports have found heterogeneity in ...
Kim Jinseog - - 2013
ABSTRACT: BACKGROUND: A popular objective of many high-throughput genome projects is to discover variousgenomic markers associated with traits and develop statistical models to predict traits offuture patients based on marker values. RESULTS: In this paper, we present a prediction method for time-to-event traits using genome-widesingle-nucleotide polymorphisms (SNPs). We also propose ...
Gijsbers Linda - - 2013
Since beneficial effects related to tomato consumption partially overlap with those related to PPARγ activation, our aim was to test extracts of tomato fruits and tomato components, including polyphenols and isoprenoids, for their capacity to activate PPARγ using the PPARγ2 CALUX reporter cell line. Thirty tomato compounds were tested; seven ...
Kostek John - - 2013
Previous research has shown mixed results regarding the effects of cognitively draining tasks, sometimes reporting that the depletion of cognitive resources increases risk taking and other times reporting that depletion leads to increases in risk aversion. Additionally, evidence has been provided demonstrating that both winning and losing can increase future ...
Conaglen Paul J - - 2013
INTRODUCTION: Various techniques have been described to try and reduce the rate of anastomotic leak following pancreaticoduodenectomy, which remains a challenge for pancreatic surgeons worldwide. We outline a technique to reinforce the pancreatic anastomosis with a double layer of fibrin glue between suture lines. METHODS: Our technique for pancreatic anastomosis ...
Niranjan Rituraj - - 2013
Significant bodies of evidences have shown different mechanisms known to be the etiological cause of Alzheimer's disease (AD) involving amyloid-beta protein accumulation, chronic inflammatory reactions, oxidative stress, proteasome inhibition, and high-cholesterol level, but the presize etiology of AD still remains enigmatic. Recent studies indicate that these mechanisms seem to be ...
Chang Le - - 2013
Accurate computational estimate of the protein-ligand binding affinity is of central importance in rational drug design. To improve accuracy of the molecular mechanics (MM) force field (FF) for protein-ligand simulations, we use a protein-specific FF derived by the fragment molecular orbital (FMO) method and by the restrained electrostatic potential (RESP) ...
Zenclussen Ana Claudia - - 2013
It has long been believed that there is no immune interaction between mother and conceptus during pregnancy. This concept changed after evidence was provided that the maternal immune system is aware of the semiallogeneic conceptus and develops strategies to tolerate it. Since then, finely regulated mechanisms of active tolerance toward ...
Rastogi Madhup - - 2013
Radiotherapy plays a major role in the treatment of cervical cancer. A successful radiotherapy program integrates both external beam and brachytherapy components. The principles of radiotherapy are strongly based on the anatomy of the organ and patterns of local and nodal spread. However, in patients with distorted anatomy, several practical ...
Molineris Ivan - - 2013
Polymorphisms in regulatory DNA regions are believed to play an important role in determining phenotype, including disease, and in providing raw material for evolution. We devised a new pipeline for the systematic identification of functional variation in human regulatory sequences. The algorithm is based on the identification of SNPs leading ...
Ferro Mark A - - 2013
The objective of this study was to examine the factor structure and longitudinal measurement invariance of the Center for Epidemiological Studies Depression Scale (CES-D). The population-based sample included 347 adult women who had children participating in the Health-related Quality of Life in Children with Epilepsy Study. Longitudinal confirmatory factor analysis ...
Al-Foheidi Meteb - - 2013
Breast cancer is the most common cancer in women worldwide. The disease remains a public health concern as recent evidence indicates that the breast cancer burden has increased mainly in developing and low-income countries (DLICs). Despite the demonstrated benefits, the debate about the real benefits and harms of breast cancer ...
Sato Yukie - - 2013
Closely related species often show adjacent geographic distributions, albeit with some overlap. This contiguity is thought to result from secondary contact between (spatially separated) diverging groups or from parapatric speciation. Fights between males of closely related species will affect their chance to mate with females of the other species, which ...
O'Leary C M CM Centre for Population Health Research, Curtin University, Perth, WA, Australia. - - 2013
To examine alcohol-use disorders in pregnant women and the extent of under-reporting. Population-based cohort study. Western Australia. Women with a birth recorded on the Western Australian Midwives Notification System (1985-2006). Mothers with an International Classification of Diseases 9/10 alcohol-related diagnosis, indicating heavy alcohol consumption, recorded on population-based health datasets (non-Aboriginal ...
Yun Y E - - 2013
Abstract 1. Rationale: Tissue-to-plasma partition coefficients (K(p)) that characterize the tissue distribution of a drug are important input parameters in physiologically based pharmacokinetic (PBPK) models. The aim of this study was to develop an empirically derived K(p) prediction algorithm using input parameters that are available early in the investigation of ...
Yoshimoto Akihiro - - 2013
OBJECTIVE: We perform bilateral pulmonary artery banding (BPAB) combined with postoperative percutaneous pulmonary artery balloon dilatation (PABD) as stage I palliation for severe congenital heart diseases. The objective of this study was to evaluate the efficacy of our management strategy for the treatment of severe congenital heart diseases. METHODS: From ...
Chin Jerome H - - 2013
There are an estimated 50 million people living with epilepsy (PLWE) worldwide.(1) In the United States and other high-income countries, PLWE are offered a wide range of advanced diagnostic and therapeutic services. In stark contrast, the vast majority of PLWE in poorer regions of the world receive no care and ...
Boland Michael V - - 2013
Glaucoma is an acquired degeneration of the optic nerve and a leading cause of blindness worldwide. Medical and surgical treatments that decrease intraocular pressure may prevent visual impairment and blindness. To compare the effectiveness of medical, laser, and surgical treatments in adults with open-angle glaucoma with regard to decreasing intraocular ...
Black S - - 2013
Expert witness opinion based on the comparison of images has been accepted by UK courts as admissible evidence in relation to issues of identity. Within images of the hand are a multiplicity of anatomical features of different aetiology, incidence and distribution patterns and this includes melanocytic nevi, referred to more ...
Xu Haixia - - 2013
The 2-DE/MS-based proteomics approach was used to investigate the differences of porcine skeletal muscle, and ATP5B was identified as one differential expression protein. In the present study, ATP5B gene was further cloned by RT-PCR, the sequence was analyzed using the bioinformatics method, and the mRNA expression was detected by qRT-PCR. ...
Hafez Aly Mohamed - - 2013
Preparation of a nano porous gold surface by dealloying (etching) of 585 gold plate (58.5% Au, 30% Ag and 11.5% non nobel metals) was studied by applying acidic and thermal treatment of the gold pate. The gold plate surface was studied before and after the etching process using different analytical ...
Kaarme Johan - - 2013
AIM: The objective was to determine the prevalence of extended spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae in feces from healthy Swedish preschool children and to establish if transmission took place between children in preschools. METHODS: Diapers from children attending preschools in Uppsala city were collected during September to October 2010 and the ...
Simões Irina N - - 2013
Mesenchymal stem cells (MSC) have the potential to be applied in therapeutic settings due to their multilineage differentiation ability, immunomodulatory properties, as well as trophic activity. Umbilical cord matrix (UCM) represents a promising source of MSC for biomedical applications. The number of isolated cells per umbilical cord (UC) unit is ...
Anegawa Go - - 2013
PURPOSE: Perforated diverticulitis (PD) remains a serious acute abdominal condition. The aim of this study was to evaluate indications for emergency surgery in patients ≥80 years of age with PD. METHOD: Twenty patients ≥80 years of age and 28 younger patients who underwent emergency surgery for PD from January 2002 to December ...
McTrusty Alice D - - 2013
BACKGROUND: The purpose of this paper is to report a case of idiopathic isolated fovea plana showing asymmetry in the multifocal electroretinogram (mfERG). METHODS: We carried out optical coherence tomography (OCT) imaging, macular pigment density measurement, genetic testing and electrophysiological testing with visual evoked potentials and mfERGs on a young, ...
Zhang Zhi-Ming - - 2013
A polyoxometalate (POM)-based {Mn(IV)(2)Mn(III)(6)Mn(II)(4)} complex with single-molecule magnet (SMM) behaviour was prepared, exhibiting the largest known Mn nuclearity and the most Mn valence states in the POM-based SMM family.
Simsek Damla Gökşen - - 2013
Aim:Epidemiologic and clinical features of type 1 diabetes mellitus (T1DM) may show substantial differences among countries. The primary goal in the management of T1DM is to prevent micro- and macrovascular complications by achieving good glycemic control. The present study aimed to assess metabolic control, presence of concomitant autoimmune diseases, and ...
Bernat James L - - 2013
Circulatory-respiratory or brain tests are widely accepted for definition and determination of death, but have several controversial issues. Both determinations have been stimulated by organ donation, but must be valid independently of this process. Current controversies in brain death include whether the definition is conceptually coherent, whether the whole-brain or ...
Dede K - - 2013
Patients with metastatic colorectal cancer receive chemotherapy prior liver resection more and more frequently. This preoperative treatment has many effects which have to be analysed, like the safety of liver resection, toxicity, tissue regeneration, radiological and pathological response and survival data. The aim of the study was to evaluate the ...
Yang Chunzhang - - 2013
Astrocytic activation is a cellular response to disturbances of the central nervous system (CNS). Recent advances in cellular and molecular biology have demonstrated the remarkable changes in molecular signaling, morphology, and metabolism that occur during astrocyte activation. Based on these studies, it has become clear that the astrocyte activation process ...
Abbasi Fahim - - 2013
Insulin-mediated glucose disposal varies severalfold in apparently healthy individuals, and approximately one-third of the most insulin resistant of these individuals is at increased risk to develop various adverse clinical syndromes. Since direct measurements of insulin sensitivity are not practical in a clinical setting, several surrogate estimates of insulin action have ...
Lavalleur Heather J - - 2013
Geological carbon sequestration in basalts is a promising solution to mitigate carbon emissions into the Earth's atmosphere. The Wallula pilot well in eastern Washington State, USA provides an opportunity to investigate how native microbial communities in basalts are affected by the injection of supercritical carbon dioxide into deep, alkaline formation ...
Hamada Tsuyoshi - - 2013
BACKGROUND: Early identification of severe cases of acute pancreatitis is necessary to reduce mortality. The Japanese severity score, which consists of nine prognostic factors, is reported to be useful for assessment of acute pancreatitis severity, but has not been validated by large-scale data. METHODS: Data on adult patients with acute ...
Deng Yating - - 2013
Gentiopicroside (GE), a naturally occurring iridoid glycoside, has been developed into a Novel Traditional Chinese Drug named Gentiopicroside injection, and it was approved for the treatment of acute jaundice and chronic active hepatitis by SFDA. However, the inhibitory and inducible effects of GE on the activity of cytochrome P450 (CYP450) ...
Rowland Kate - - 2013
QUESTION Does a clinical prediction rule based on data collected at hospital admission predict risk for death and severe disability after acute ischemic stroke? METHODS DESIGN Registry-based cohort study with individual patient linkage to administrative databases and separate derivation and validation cohorts. SETTING 11 regional stroke centers in Ontario, Canada. ...
Irvine Gail V - - 2013
Probability-based designs reduce bias and allow inference of results to the pool of sites from which they were chosen. We developed and tested probability-based designs for monitoring marine rocky intertidal assemblages at Glacier Bay National Park and Preserve (GLBA), Alaska. A multilevel design was used that varied in scale and ...
Rybi-Szumińska Agnieszka - - 2013
AIM: The objective of this study was to establish age-dependent urine NGAL (neutrophil gelatinase associated lipocalin) /creatinine ratio values in healthy children and adolescents. METHODS: The study was performed using a random sample of 172 healthy children and adolescents (M - 88, F - 84), aged median 9.75 (0.2 - ...
Berlowska Joanna - - 2013
The adhesion of cells to solid supports is described as surface-dependent, being largely determined by the properties of the surface. In this study, ceramic surfaces modified using different organosilanes were tested for proadhesive properties using industrial brewery yeast strains in different physiological states. Eight brewing strains were tested: bottom-fermenting Saccharomyces ...
Guo Zelei - - 2013
The maximum oscillation frequency (fmax) quantifies the practical upper bound for useful circuit operation. We report here an fmax of 70 GHz in transistors using epitaxial graphene grown on the C-face of SiC. This is a significant improvement over Si-face epitaxial graphene used in the prior high frequency transistor studies, ...
Pragasam Samuel Joshua - - 2013
OBJECTIVE: This study was conducted to evaluate the effect of p-Coumaric acid, a common dietary phenol, on monosodium urate crystal-induced inflammation in rats-an experimental model for acute gouty arthritis. METHODS: Paw edema, levels/activities of lysosomal enzymes, lipid peroxidation, enzymic antioxidants and a histopathological examination of ankle joints were evaluated in ...
Marques Carlos F C - - 2013
Aqueous biphasic systems (ABS) using ionic liquids (ILs) offer an alternative approach for the extraction, recovery and purification of biomolecules through their partitioning between two aqueous liquid phases. In this work, the ability of a wide range of ILs to form ABS with aqueous solutions of Na(2) CO(3) was evaluated. ...
Opletal George - - 2013
A structural study is presented of ab initio molecular dynamics simulations of Ge-As-Se chalcogenide glasses performed at the same mean coordination number but differing stoichiometry ranging between Se rich and Se poor glasses. Starting configurations are generated via Reverse Monte Carlo (RMC) simulations of Extended X-ray Absorption Fine Structure (EXAFS) ...
Seijo Susana - - 2013
OBJECTIVES:Idiopathic portal hypertension (IPH) is a rare cause of portal hypertension that lacks a specific diagnostic test. Requiring ruling-out other causes of portal hypertension it is frequently misdiagnosed. This study evaluates whether using high-throughput techniques there is a metabolomic profile allowing a noninvasive diagnosis of IPH.METHODS:Thirty-three IPH patients were included. ...
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