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Results 101 - 150 of 1922
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Hynes Denise M - - 2013
: The Department of Veterans Affairs (VA) Quality Enhancement Research Initiative (QUERI) has demonstrated how implementation science can enhance the quality of health care. During this time an increasing number of implementation research projects have developed or utilized health information technology (HIT) innovations to leverage the VA's electronic health record ...
Rahe-Meyer Niels - - 2013
We assessed whether fibrinogen concentrate as targeted first-line hemostatic therapy was more effective than placebo or a standardized transfusion algorithm in controlling coagulopathic bleeding in patients undergoing major aortic surgery. In this single-center, prospective, double-blind study, adults undergoing elective thoracic or thoracoabdominal aortic replacement surgery involving cardiopulmonary bypass were randomized ...
Nguyen Dang Khoa - - 2013
Purpose: To evaluate the prevalence of nonlesional focal epilepsy in an adult epilepsy clinic and its refractoriness to antiepileptic drug therapy. Background: Focal epilepsy is frequently, but not always, associated with structural epileptogenic lesions identifiable on magnetic resonance imaging (MRI). Methods: We analyzed the data from all patients evaluated at ...
Schapiro Naomi A - - 2013
There are increasing numbers of mothers as well as fathers who engage in long-term migration to support their children and other family members in their home countries. In this article, the current state of the literature about children and adolescents left at home in these transnational families is surveyed and ...
Hagl Christian - - 2013
Aneurysmal diseases are often silent but can cause potentially life-threatening complications in cases of dissection or rupture. Surgical strategies depend on the involved part of the aorta and frequently require extracorporeal circulation and circulatory arrest. From data available from the Centers for Disease Control and Prevention, aneurysm disease is the ...
Salman Michael S - - 2013
Introduction: Infantile-onset saccade initiation delay (ISID), also known as congenital ocular motor apraxia, is characterized by the inability to initiate volitional horizontal saccades. Other abnormalities including developmental delay and ataxia have been reported. The frequency of these abnormalities is unknown. We performed a detailed review of the medical literature to ...
Sanmaneechai Oranee O Saul R. Korey Department of Neurology, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, New York, USA. - - 2013
We report the case of an adolescent girl with anti-N-methyl-D-aspartate-receptor (NMDAR) encephalitis who presented with focal seizures and hemichorea, followed by agitation, speech disturbance, mutism, and autonomic dysfunction. The institution of immunotherapy and removal of an ovarian cystadenofibroma led to full resolution of her symptoms with disappearance of serum NMDAR ...
Donohoe Charles D - - 2013
The most critical element in headache evaluation is the history. The targeted history differentiates primary from secondary headaches and provides a realistic list of conditions associated with secondary headache. Several of these conditions present with specific physical findings, such as papilledema, Horner's syndrome, or a cranial nerve palsy. The targeted ...
Dawson Anton A Department of Pharmacology and Toxicology, Virginia Commonwealth University, MCV Campus, Box 980613, Richmond, VA 23298-0613, USA. - - 2013
The high co-morbidity between alcohol (ethanol) and nicotine abuse suggests that nicotinic acetylcholine receptors (nAChRs), thought to underlie nicotine dependence, may also be involved in alcohol dependence. The β2* nAChR subtype serves as a potential interface for these interactions since they are the principle mediators of nicotine dependence and have ...
- - 2013
MODERATOR: Joseph E. Bavaria, MD, Philadelphia, Pa. PANELISTS: Randall B. Griepp, MD, Mount Sinai School of Medicine, New York, NY; David Spielvogel, MD, Westchester Medical Center, Valhalla, NY; Yukata Okita, MD, Kobe University, Kobe, Japan; Hitoshi Ogino, MD, PhD, Department of Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Suita, Japan; ...
Pulickal Anoop S - - 2013
We report a 14-month old child with multiple episodes of febrile status epilepticus, followed by chorea and developmental regression, caused by human herpes virus-6 encephalitis. Chorea has been described as a complication of relapsing herpes simplex virus I infection, but not as a manifestation of human herpes virus-6 infection. It ...
Del Campo Marta L - - 2013
Plant phenolics are generally thought to play significant roles in plant defense against herbivores and pathogens. Many plant taxa, including Solanaceae, are rich in phenolic compounds and some insect herbivores have been shown to acquire phenolics from their hosts to use them as protection against their natural enemies. Here we ...
Lange Rüdiger - - 2013
The European transcatheter aortic valve implantation experience began in 2002, and ever since, numerous centers have started a program, resulting in a "transcatheter aortic valve implantation pandemic." Considerable experience has been gained with various access routes for implantation and with valve-in-surgical bioprosthetic valve procedures. Reimbursement differs among the European countries ...
Menon Bijoy K - - 2013
Objective/Background: We describe the internal cerebral vein (ICV) sign, which is a hypo-opacification of the ICV on computed tomogram angiography (CTA) as a new marker of increased cerebral blood transit-time in ipsilateral internal carotid artery occlusions (ICAO). Methods: A retrospective analysis of 153 patients with acute unilateral M1 middle cerebral ...
Ulbricht Catherine - - 2013
ABSTRACT An evidence-based systematic review of tongkat ali (Eurycoma longifolia) by the Natural Standard Research Collaboration consolidates the safety and efficacy data available in the scientific literature using a validated, reproducible grading rationale. This article includes written and statistical analysis of clinical trials, plus a compilation of expert opinion, folkloric ...
Krist Mark R MR Department of Rehabilitation, Nursing Science & Sports, University Medical Centre, Utrecht, The Netherlands. - - 2013
Is an injury prevention program consisting of 10 exercises designed to improve stability, muscle strength, co-ordination, and flexibility of the trunk, hip and leg muscles (known as The11) cost effective in adult male amateur soccer players? Cost-effectiveness analysis of a cluster-randomised controlled trial. 479 adult male amateur soccer players aged ...
Shen Guofeng G Laboratory of Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing, 100871, - - 2013
Air pollutants from residential solid fuel combustion are attracting growing public concern. Field measured emission factors (EFs) of various air pollutants for solid fuels are close to the reality and urgently needed for better emission estimations. In this study, emission factors of particulate matter (PM), organic carbon (OC), elemental carbon ...
Yang Feng-Hua - - 2013
Mild head trauma can cause cerebral infarction in children younger than 18 months of age, yet the pathogenesis, clinical characteristics, and risk factors are not fully understood. Data of 16 cases between August 2008 and September 2011, including clinical manifestations and imaging and laboratory findings were collected and analyzed. All ...
Forbes Ashley - - 2013
Ethanol has well described acute effects on motor function, and chronic alcoholism can damage the cerebellum, which is associated with motor coordination, as well as motor learning. Binge drinking is common among preadolescents and adolescents, and this type of ethanol exposure may lead to long-term nervous system damage. In the ...
Blachier Martin - - 2013
To survey the burden of liver disease in Europe and its causes 260 epidemiological studies published in the last five years were reviewed. The incidence and prevalence of cirrhosis and primary liver cancer are key to understand the burden of liver disease. They represent the end-stage of liver pathology and ...
Wickerson Lisa - - 2013
In patients immediately following lung transplant, does three months of supervised exercise training confer changes in physical activity during daily life, functional exercise capacity, muscle force, health-related quality of life (HRQL), or forced expiratory volume in one second (FEV(1))? Randomised, controlled trial with concealed allocation in which investigators responsible for ...
Horn Morten A - - 2013
To investigate X-linked adrenoleukodystrophy in an unselected population, we performed a population based, cross-sectional prevalence study, supplemented by a retrospective study of deceased subjects. Sixty-three subjects (34 males, 29 females) belonging to 22 kindreds were included. Thirty-nine subjects (13 males, 26 females) were alive, and 24 (21 males, 3 females) ...
Gray J - - 2013
It has been more than 40 years since a major position paper on clinical pharmacology was published by the World Health Organization (WHO). A recent publication, Clinical Pharmacology in Health Care, Teaching, and Research, provides a current vision of the discipline suitable for the twenty-first century.
- - 2013
MODERATOR: Steven L. Lansman, MD, PhD, Westchester Medical Center, Valhalla, NY. PANELISTS: Wilson Y. Szeto, MD, Hospital of the University of Pennsylvania, Philadelphia, Pa; Giampiero Esposito, MD, Department of Cardiovascular Disease, Cliniche Humanitas, Gavazzeni, Bergamo, Italy; Niels Rahe-Meyer, MD, Clinic for Anesthesiology and Intensive Care Medicine, Franziskus Hospital Bielefeld, Germany; ...
Kremenchutzky Marcelo - - 2013
Objective: To compare neurologist and patient perceptions of multiple sclerosis (MS)-related health status. Methods: MS patients (n=99) were recruited from six sites in Canada. Following a consultation with their neurologist, patients estimated their relapse frequency, rated their general health and quality of life (QoL), reviewed descriptions of eight health domains ...
Szeto Wilson Y - - 2013
Thoracic endovascular aortic repair has emerged as an effective therapy for a variety of thoracic aortic pathologic entities. However, endograft failure remains a concern, and its treatment is often challenging. We examined our experience with endograft failure and its treatment by endovascular and open repair. From January 2000 to January ...
Lecavalier-Barsoum Magali M Radiation Oncology Department, McGill University Health Center, Canada. - - 2013
Stereotactic radiosurgery (SRS) is known to safely result in a high obliteration rate for small and medium sized arteriovenous malformations (AVM). To evaluate the long-term outcome of patients treated with SRS, with special emphasis given to obliteration and toxicity rates. We performed a review of 43 cerebral AVM patients, treated ...
- - 2013
MODERATOR: Nicholas T. Kouchoukos, MD, St. Louis, Mo. PANELIST: Dianna M. Milewicz, MD, University of Texas Medical School at Houston, Houston, Texas; Alan C. Braverman, MD, Washington University School of Medicine, St. Louis, Mo; Michael Mack, MD, Baylor Health Care System, Plano, Texas; Lars G. Svensson, MD, Cleveland Clinic, Cleveland, ...
Zeiler Frederick A - - 2013
Background: Ultrasonic assessment of optic nerve sheath diameter (ONSD) as a non-invasive measure of intracranial pressure (ICP) has been evaluated in the literature as a potential valid technique for rapid ICP estimation in the absence of invasive intracranial monitoring. The technique can be challenging to perform and little literature exists ...
Dhamija Radhika - - 2013
About one third of patients with epilepsy are pharmacoresistent. For a subgroup of this population, the ketogenic diet can be highly efficacious and should be considered early. This review discusses the different types of ketogenic diet, proposed mechanism of actions and its evidence for use in children and adults with ...
Svensson Lars G - - 2013
Percutaneous transcatheter aortic valve replacement was introduced in 2002, but its effectiveness remained to be assessed. A prospective, randomized trial (the Placement of Aortic Transcatheter Valves, or PARTNER) was designed with 2 arms: PARTNER A (n = 699) for high-risk surgical patients (Society of Thoracic Surgeons score >10%, surgeon assessed risk of mortality >15%) ...
Villafañe Jorge H - - 2013
In people with thumb carpometacarpal osteoarthritis, does radial nerve mobilisation to the affected hand reduce pressure pain sensitivity in the contralateral hand? Secondary analysis of data from a randomised trial with concealed allocation, assessor blinding, and intention-to-treat analysis. Sixty people with thumb CMC osteoarthritis in the dominant hand aged 70-90 ...
Peiris Casey L - - 2013
Are ambulant patients who are admitted for inpatient rehabilitation for a lower limb orthopaedic condition active enough to meet current physical activity guidelines? Prospective observational study. Adults admitted for inpatient rehabilitation for a lower limb orthopaedic condition who were cognitively alert and able to walk independently or with assistance. Participants ...
Upjohn M M - - 2013
The relative merits and potential complementarity of participatory methods and classical epidemiological techniques in veterinary-related research is a current topic of discussion. Few reported studies have applied both methodologies within the same research framework to enable direct comparison. The aim of this study was to compare issues identified by a ...
Abraham Cherrie Z - - 2013
To present an initial experience with a new modular transfemoral multibranched stent-graft for treating aortic arch aneurysms. Six patients, considered high risk for open surgery, were treated with a custom-made branched stent-graft. Two patients had aortic arch aneurysms, three had descending thoracic aortic aneurysms involving the distal arch, and one ...
Etz Christian D - - 2013
To determine the effect of different etiologies on the outcome and mortality after mechanical composite aortic root/ascending replacement. From February 1998 to June 2011, 448 consecutive patients (358 men, age, 52.8 ± 12.3 years) underwent composite mechanical aortic root replacement. Of these 448 patients, 362 (80.8%) were treated for degenerative/atherosclerotic root/ascending aortic ...
- - 2013
The Australian Institute of Health and Welfare (AIHW) is a major national agency established by the Australian government to provide reliable, regular and relevant information and statistics on Australia's health and welfare. The AIHW publishes updated information on survival and prevalence of cancer in Australia on a regular basis. The ...
Hassan Ali - - 2013
Background: Electromyography (EMG) for suspected cervical or lumbosacral root compression is often negative, producing expense and physical discomfort that could have been avoided. To improve patient selection for testing, we sought to identify clinical features that would accurately predict presence of radiculopathy on EMG. Methods: Adult patients consecutively evaluated for ...
Gabrys Charles M CM Department of Chemistry, Michigan State University , East Lansing, Michigan 48824, United - - 2013
Fusion of the human immunodeficiency virus (HIV) membrane and the host cell membrane is an initial step of infection of the host cell. Fusion is catalyzed by gp41, which is an integral membrane protein of HIV. The fusion peptide (FP) is the ∼25 N-terminal residues of gp41 and is a ...
Mosberg Henry I HI Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States. - - 2013
We have previously described opioid peptidomimetic, 1, employing a tetrahydroquinoline scaffold and modeled on a series of cyclic tetrapeptide opioid agonists. We have recently described modifications to these peptides that confer a μ opioid receptor (MOR) agonist, δ opioid receptor (DOR) antagonist profile, which has been shown to reduce the ...
Platzman Ilia - - 2013
Activation, ex vivo expansion of T cells, differentiation into a regulatory subset, and its phenotype-specific high-throughput selection represent major challenges in immunobiology. In part, this is due to the lack of technical means to synthesize suitable 3D extracellular systems to imitate ex vivo the cellular interactions between T cells and ...
Szepes Attila A Bács-Kiskun Megyei Kórház, a Szegedi Tudományegyetem Általános Orvostudományi Kar Oktató Kórháza Belgyógyászati Osztály. - - 2013
Sphincter of Oddi dysfunction usually occurs after cholecystectomy, but it can sometimes be detected in patients with intact gallbladder too. The diagnostic value of the non-invasive functional tests is not established in this group of patients and the effects of sphincterotomy on transpapillary bile outflow and gallbladder motility are unknown. ...
Buzás György Miklós - - 2013
After a short overview of the history of probiotics, the author presents the development of human intestinal microflora based on the newest genetic data and the microbiological features of main probiotics. The indications of probiotic administration have been defined and extended in recent years. The author reviews significant results of ...
Feldman Karolina - - 2013
Glucocorticoids play an important role in the regulation of carbohydrate and amino acid metabolism, they modulate the function of the immune system, and contribute to stress response. Increased and decreased production of glucocorticoids causes specific diseases. In addition to systemic hypo- or hypercortisolism, alteration of local synthesis and metabolism of ...
Lerman Gilad M - - 2013
Great hopes rest on surface plasmon polaritons' (SPPs) potential to bring new functionalities and applications into various branches of optics. In this paper, we demonstrate a pin cushion structure capable of coupling light from free space into SPPs, split them based on the polarization content of the illuminating beam of ...
Terheggen G - - 2013
Cholangioscopy is an important component of the management of a selected group of patients with biliary diseases. Due to the advantage of direct visualization cholangioscopy provides targeted diagnostic and therapeutic procedures under endoscopic control. Thus cholangioscopy improves the differentiation of benign and malignant intraductal lesions, targeted biopsies and precise delineation ...
Takubo K - - 2013
The definition of early carcinoma of the esophagus has changed with time on the basis of new data. As from 2007 an early carcinoma is defined as an intramucosal carcinoma with or without metastasis. In the subclassification based on invasion depth, m1 and m2 squamous cell carcinomas have no metastasis ...
Inoue T - - 2013
PURPOSE: The aim of this retrospective study was to evaluate the feasibility, safety, and effectiveness of stereotactic body radiotherapy (SBRT) for pulmonary metastases. PATIENTS AND METHODS: Between April 2007 and March 2011, 87 patients underwent SBRT for pulmonary metastases using the in-house Air-Bag System(TM) to obtain the four-dimensional image for treatment ...
Zaganas Ioannis - - 2013
Glutamate dehydrogenase (GDH) uses ammonia to reversibly convert α-ketoglutarate to glutamate using NADP(H) and NAD(H) as cofactors. While GDH in most mammals is encoded by a single GLUD1 gene, humans and other primates have acquired a GLUD2 gene with distinct tissue expression profile. The two human isoenzymes (hGDH1 and hGDH2), ...
Wang P-M - - 2013
PURPOSE: The aim of this article is to report the dosimetric and clinical findings in the treatment of primary hepatocellular carcinoma (HCC) with volumetric modulated arc therapy (VMAT, RapidArc). METHODS AND MATERIALS: A total of 138 patients were investigated. Dose prescription ranged from 45-66 Gy. Most patients (88.4 %) presented AJCC stage III ...
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