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Results 51 - 100 of 1922
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Tahir Mir - - 2013
The present investigation was designed to evaluate the efficacy of diosmin against ethanol-induced hepatotoxicity in rats by modulating various mechanisms including ethanol metabolizing enzymes, generation of free radicals, imbalance in oxidant-antioxidant status, oxidative damage to membrane lipids, activation of transcription factors and elevation in inflammatory markers involved in ethanol-induced hepatic ...
Yokoi Yoshihiko - - 2013
We evaluated the results of our previous study investigating a precurved fenestrated endograft treatment for thoracic aortic aneurysms and aortic dissection extended to the aortic arch. From February 2010 to December 2011 at 35 Japanese centers, 383 patients (mean age, 75.7 ± 9.4 years) who required stent-graft landing in the aortic arch ...
- - 2013
MODERATOR: Nicholas T. Kouchoukos, MD, St. Louis, Mo. PANELIST: Dianna M. Milewicz, MD, University of Texas Medical School at Houston, Houston, Texas; Alan C. Braverman, MD, Washington University School of Medicine, St. Louis, Mo; Michael Mack, MD, Baylor Health Care System, Plano, Texas; Lars G. Svensson, MD, Cleveland Clinic, Cleveland, ...
Zeiler Frederick A - - 2013
Background: Ultrasonic assessment of optic nerve sheath diameter (ONSD) as a non-invasive measure of intracranial pressure (ICP) has been evaluated in the literature as a potential valid technique for rapid ICP estimation in the absence of invasive intracranial monitoring. The technique can be challenging to perform and little literature exists ...
Sundt Thoralf M - - 2013
Endografting for treatment of thoracic aortic pathology continues to gain popularity; in some countries, endovascular aortic repair numbers now exceed open surgery cases. The skills and understanding of open surgical teams are not always translated into endovascular interventions, which may be led by a cardiologist or vascular surgeon with little ...
Turnacioglu Sinan - - 2013
Pediatric neurologists and developmental pediatricians may evaluate patients with primary or associated behavioral and academic concerns. A critical element of the evaluation involves determining that the child's condition is not better explained by underlying inherited metabolic disorders. In this review, psychiatric and behavioral presentations of inherited metabolic disorders are discussed ...
Yen Cheng-Fang - - 2013
Aims  This study provides a systematic review of existing research that has evaluated unique gambling experiences in Taiwan. Methods  A comprehensive review of electronic databases, including Scopus, PubMed, Chinese Electronic Periodical Services and the Index to Taiwan Periodical Literature System, was conducted to identify evaluations of gambling experiences in Taiwan. ...
Drenberg C D - - 2013
Tyrosine kinases have emerged as important tumor targets for the design of potent and selective inhibitors. Eighteen of these tyrosine kinase inhibitors (TKIs) have already been approved for the treatment of diseases that were previously essentially resistant to standard chemotherapy. Major efforts are ongoing that focus on the development of ...
Amoozegar Farnaz - - 2013
A literature search found no clinical trials or guidelines addressing the management of spontaneous intracranial hypotension (SIH). Based on the available literature and expert opinion, we have developed recommendations for the diagnosis and management of SIH. For typical cases, we recommend brain magnetic resonance (MR) imaging with gadolinium to confirm ...
Matsuo Muneaki - - 2013
Acute encephalopathy with biphasic seizures and late reduced diffusion was recently established clinicoradiologically as an encephalopathy syndrome. The outcome of this encephalopathy is characterized by a low mortality rate and high incidence of neurologic sequelae. Although the exact pathogenesis of this encephalopathy is uncertain, excitotoxic injury with delayed neuronal death ...
Mortenson Eric D - - 2013
Oncogenic signaling, such as HER2/neu signaling, has been shown to play major role for tumorigenesis in a subset of breast cancer patients. The use of anti-HER2/neu antibody has not only revealed the mechanisms for HER2/neu signaling but also shown a therapeutic advantage of its blockade. Indeed, the use of trastuzumab ...
Donohoe Charles D - - 2013
The most critical element in headache evaluation is the history. The targeted history differentiates primary from secondary headaches and provides a realistic list of conditions associated with secondary headache. Several of these conditions present with specific physical findings, such as papilledema, Horner's syndrome, or a cranial nerve palsy. The targeted ...
- - 2013
MODERATOR: Steven L. Lansman, MD, PhD, Westchester Medical Center, Valhalla, NY. PANELISTS: Wilson Y. Szeto, MD, Hospital of the University of Pennsylvania, Philadelphia, Pa; Giampiero Esposito, MD, Department of Cardiovascular Disease, Cliniche Humanitas, Gavazzeni, Bergamo, Italy; Niels Rahe-Meyer, MD, Clinic for Anesthesiology and Intensive Care Medicine, Franziskus Hospital Bielefeld, Germany; ...
Kremenchutzky Marcelo - - 2013
Objective: To compare neurologist and patient perceptions of multiple sclerosis (MS)-related health status. Methods: MS patients (n=99) were recruited from six sites in Canada. Following a consultation with their neurologist, patients estimated their relapse frequency, rated their general health and quality of life (QoL), reviewed descriptions of eight health domains ...
Waldman Steven D - - 2013
The targeted headache history is paramount in the diagnosis of headache and facial pain. Through placing symptoms in categories, a clear picture of the headache diagnosis will begin to emerge. The physical examination yields no positive findings in most patients with headache. Medication overuse headache is emerging as a common ...
Yang Feng-Hua - - 2013
Mild head trauma can cause cerebral infarction in children younger than 18 months of age, yet the pathogenesis, clinical characteristics, and risk factors are not fully understood. Data of 16 cases between August 2008 and September 2011, including clinical manifestations and imaging and laboratory findings were collected and analyzed. All ...
Griepp Randall B - - 2013
Hypothermic circulatory arrest has been used during aortic arch repairs with acceptable neurologic outcomes. Through the years, we have studied the effects of deep hypothermia on brain metabolism and perfusion both in a pig model and in surgical patients. Hypothermic circulatory arrest has also been used as a method of ...
Roberts-South Angela - - 2013
Background: Management of chronic diseases such as movement disorders can be challenging. Nurse-administered telephone follow-up programs have demonstrated clinical and cost efficacy in a variety of health care models. However, their efficacy in movement disorders has not been sufficiently addressed. This observational study fills a knowledge gap by reporting the ...
Etz Christian D - - 2013
To determine the effect of different etiologies on the outcome and mortality after mechanical composite aortic root/ascending replacement. From February 1998 to June 2011, 448 consecutive patients (358 men, age, 52.8 ± 12.3 years) underwent composite mechanical aortic root replacement. Of these 448 patients, 362 (80.8%) were treated for degenerative/atherosclerotic root/ascending aortic ...
- - 2013
The Australian Institute of Health and Welfare (AIHW) is a major national agency established by the Australian government to provide reliable, regular and relevant information and statistics on Australia's health and welfare. The AIHW publishes updated information on survival and prevalence of cancer in Australia on a regular basis. The ...
Hassan Ali - - 2013
Background: Electromyography (EMG) for suspected cervical or lumbosacral root compression is often negative, producing expense and physical discomfort that could have been avoided. To improve patient selection for testing, we sought to identify clinical features that would accurately predict presence of radiculopathy on EMG. Methods: Adult patients consecutively evaluated for ...
Goyal Monisha - - 2013
Although pyridoxine-dependent seizures have been reported for decades, pyridoxamine phosphate oxidase deficiency has only been recently described. Pyridoxamine phosphate oxidase (PNPO) is one of a series of enzymes involved in converting pyridoxine to pyridoxal 5'-phosphate, the biologically active form of pyridoxine. PNPO deficiency is associated with decreased levels of pyridoxal ...
Rahe-Meyer Niels - - 2013
We assessed whether fibrinogen concentrate as targeted first-line hemostatic therapy was more effective than placebo or a standardized transfusion algorithm in controlling coagulopathic bleeding in patients undergoing major aortic surgery. In this single-center, prospective, double-blind study, adults undergoing elective thoracic or thoracoabdominal aortic replacement surgery involving cardiopulmonary bypass were randomized ...
Nguyen Dang Khoa - - 2013
Purpose: To evaluate the prevalence of nonlesional focal epilepsy in an adult epilepsy clinic and its refractoriness to antiepileptic drug therapy. Background: Focal epilepsy is frequently, but not always, associated with structural epileptogenic lesions identifiable on magnetic resonance imaging (MRI). Methods: We analyzed the data from all patients evaluated at ...
Schapiro Naomi A - - 2013
There are increasing numbers of mothers as well as fathers who engage in long-term migration to support their children and other family members in their home countries. In this article, the current state of the literature about children and adolescents left at home in these transnational families is surveyed and ...
Spears Gwendolyn V - - 2013
: Falls are the leading cause of unintentional injury among US older adults. Guidelines recommend screening patients for fall risk, and providing exercise for patients with gait and balance problems. We redesigned an electronic clinical reminder to improve identification and management of Veterans at high risk for falls, and piloted ...
Rana Maunak V - - 2013
Cervicogenic headache (CGH) is a controversial topic in the treatment of patients with chronic cephalgia. This article reviews and summarizes the points of contention, historical significance, differential diagnosis, and treatments for CGH. This information will be of benefit to clinicians treating patients with this condition and assist providers in reviewing ...
Lange Rüdiger - - 2013
The European transcatheter aortic valve implantation experience began in 2002, and ever since, numerous centers have started a program, resulting in a "transcatheter aortic valve implantation pandemic." Considerable experience has been gained with various access routes for implantation and with valve-in-surgical bioprosthetic valve procedures. Reimbursement differs among the European countries ...
Menon Bijoy K - - 2013
Objective/Background: We describe the internal cerebral vein (ICV) sign, which is a hypo-opacification of the ICV on computed tomogram angiography (CTA) as a new marker of increased cerebral blood transit-time in ipsilateral internal carotid artery occlusions (ICAO). Methods: A retrospective analysis of 153 patients with acute unilateral M1 middle cerebral ...
Forbes Ashley - - 2013
Ethanol has well described acute effects on motor function, and chronic alcoholism can damage the cerebellum, which is associated with motor coordination, as well as motor learning. Binge drinking is common among preadolescents and adolescents, and this type of ethanol exposure may lead to long-term nervous system damage. In the ...
Abenhaim Halpern Lea - - 2013
Mild encephalopathy with reversible splenial lesions has mainly been associated with influenza A and B virus infection. Patients present with neurologic symptoms 1 to 3 days after a prodromal illness and recover completely within a few days. Magnetic resonance imaging typically shows reversible lesions with reduced diffusion in the corpus ...
Tsai Thomas T - - 2013
: Timely identification and reporting of medical device problems is critical to postmarket device surveillance programs to maximize patient safety. Cardiac catheterization laboratories are high-device utilization areas well suited for device surveillance. : To demonstrate the feasibility of the national VA Clinical Assessment, Reporting, and Tracking (CART) system, embedded in ...
Aksoy Ayse - - 2013
Acute disseminated encephalomyelitis is an acute demyelinating disorder of the central nervous system, which principally affects the brain and spinal cord. It usually follows a benign infection or vaccination in children. Although a number of infectious agents have been implicated in acute disseminated encephalomyelitis, Toxoplasma gondii infection has not been ...
Silberstein Stephen D - - 2013
Trigeminal autonomic cephalalgias are short-lasting primary headache disorders associated with autonomic symptoms. Paroxysmal hemicrania is a rare headache disorder similar to cluster headache. Short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) and short-lasting unilateral neuralgiform headache attacks with cranial autonomic symptoms (SUNA) are unusual headache syndromes typified ...
Hackl Sabine - - 2013
To date, little is known about the morphology of optic discs in premature infants. However, optic disc morphology and optic nerve development are two factors that potentially influence visual function in infants. Thus we analysed the morphology of the optic disc and its correlation with gestational age and birth weight. ...
Larovere Kerri L - - 2013
Pediatric neurocritical care is developing specialization within pediatric intensive care and pediatric neurology practice, and the evolving clinical expertise has relevance to training and education in both fields. We describe a model of service using a Neurology Consulting Team in the intensive care unit setting. Medical records were reviewed from ...
Gill Fenella J - - 2013
Aim: To explore critical care patients and families experiences and seek their input into nurses' postgraduate educational preparation and practice. Background: There is an inconsistency in the expected standard of practice to 'qualify' Australian critical care nurses. There has also been a lack of health consumer input in the development ...
Dhamija Radhika - - 2013
About one third of patients with epilepsy are pharmacoresistent. For a subgroup of this population, the ketogenic diet can be highly efficacious and should be considered early. This review discusses the different types of ketogenic diet, proposed mechanism of actions and its evidence for use in children and adults with ...
Hagl Christian - - 2013
Aneurysmal diseases are often silent but can cause potentially life-threatening complications in cases of dissection or rupture. Surgical strategies depend on the involved part of the aorta and frequently require extracorporeal circulation and circulatory arrest. From data available from the Centers for Disease Control and Prevention, aneurysm disease is the ...
Salman Michael S - - 2013
Introduction: Infantile-onset saccade initiation delay (ISID), also known as congenital ocular motor apraxia, is characterized by the inability to initiate volitional horizontal saccades. Other abnormalities including developmental delay and ataxia have been reported. The frequency of these abnormalities is unknown. We performed a detailed review of the medical literature to ...
Nzwalo Hipólito - - 2013
Moyamoya disease is an idiopathic progressive steno-occlusive disorder of the intracranial arteries located at the base of the brain. It is associated with the development of compensatory extensive network of fine collaterals. Moyamoya disease is considered syndromic when certain genetic or acquired disorders such as polycystic kidney disease, neurofibromatosis, or ...
Trafton Jodie A - - 2013
: To describe the design and deployment of health information technology to support implementation of mental health services policy requirements in the Veterans Health Administration (VHA). : Using administrative and self-report survey data, we developed and fielded metrics regarding implementation of the requirements delineated in the VHA Uniform Mental Health ...
Troisi Nicola - - 2013
Open surgical replacement of the whole aorta in mega aorta syndrome remains a surgical challenge. We report our experience in the treatment of patients with mega aorta syndrome using a 3-stage hybrid repair. From January 2006 to December 2011, 12 patients with mega aorta syndrome underwent total replacement of the ...
Mai Lauren M - - 2013
Background: Screening for cognitive impairment is recommended in patients with cerebrovascular disease. We sought to establish the incidence of cognitive impairment using the Montreal Cognitive Assessment (MoCA) in a cohort of consecutive patients attending our stroke prevention clinic (SPC), and to determine whether a subset of the MoCA could be ...
- - 2013
MODERATOR: Randall B. Griepp, MD, New York, NY. PANELISTS: Joseph S. Coselli, MD, Texas Heart Institute, Baylor College of Medicine, Houston, Tex; John Elefteriades, MD, Yale University School of Medicine, New Haven, Conn; Gabriele Di Luozzo, MD, Mount Sinai School of Medicine, New York, NY; Hazim J. Safi, MD, University ...
Lam Thach D - - 2013
Background: The risk of stroke in patients with asymptomatic carotid stenosis (ACS) is now so low that it is important to have methods to identify those patients most likely to benefit from intervention, or who may require special consideration in choice of medical therapy. We studied the prediction of stroke, ...
El-Gengaihi Souad E - - 2013
ABSTRACT This study was designed to investigate the potential of Physalis peruviana root as a functional food with hepato-renal protective effects against fibrosis. The chemical composition of the plant root suggested the presence of alkaloids, withanolides and flavonoids. Five compounds were isolated and their structures elucidated by different spectral analysis ...
Szeto Wilson Y - - 2013
Thoracic endovascular aortic repair has emerged as an effective therapy for a variety of thoracic aortic pathologic entities. However, endograft failure remains a concern, and its treatment is often challenging. We examined our experience with endograft failure and its treatment by endovascular and open repair. From January 2000 to January ...
Lecavalier-Barsoum Magali - - 2013
Background: Stereotactic radiosurgery (SRS) is known to safely result in a high obliteration rate for small and medium sized arteriovenous malformations (AVM). Objective: To evaluate the long-term outcome of patients treated with SRS, with special emphasis given to obliteration and toxicity rates. Methods: We performed a review of 43 cerebral ...
Behpour Amir M - - 2013
A systematic review was performed to assess whether cerebral blood flow with different imaging modalities could identify brain abnormalities in children with sickle cell disease where structural magnetic resonance imaging and transcranial Doppler velocity appeared normal. A total of 11 studies were identified which reported cerebral blood flow abnormalities alongside ...
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