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Results 451 - 500 of 1922
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Incerti Parenti S - - 2013
OBJECTIVES: To test the reliability of 4 different methods of measuring maxillary canine inclination (CI) on panoramic radiographs, and to determine whether examiner experience level influenced these measurements under ideal experimental conditions. SETTING AND SAMPLE POPULATION: The sample consisted of 20 high-quality panoramic radiographs obtained under standardized conditions using the ...
Hosen Naoki - - 2013
Multiple myeloma (MM) is characterized by the clonal expansion of malignant plasma cells. As in other cancers, MM plasma cells are thought to be derived from MM-initiating cells, although these remain unidentified. MM patients harbor phenotypic CD19(+) B cells expressing the immunoglobulin gene sequence and the idiotype unique to the ...
Meireles Catarina - - 2013
The adaptive flexibility of bacteria largely contributes to the emergence of antibiotic resistance, eventually leading to the predictable failure of current antimicrobial therapies. It is of utmost importance to improve current approaches and implement new ways to control bacterial growth and proliferation. A promising strategy lies in unraveling the antimicrobial ...
Perbal Bernard - - 2013
The CCN family of proteins includes six members presently known as CCN1, CCN2, CCN3, CCN4, CCN5 and CCN6. These proteins were originally designated CYR61, CTGF, NOV, and WISP-1, WISP-2, WISP-3. Although these proteins share a significant amount of structural features and a partial identity with other large families of regulatory ...
Oseguera Montiel David - - 2013
Brucellosis is a major constraint for small-scale goat farming systems in Mexico. This study estimated the prevalence of testing positive to brucellosis and identified and quantified risk factors in goats from small-scale farms of Michoacán that had participated in a brucellosis campaign (i.e. vaccination, serological testing, culling and awareness) and ...
Lee Je-Hwan - - 2013
Two DNA methyltransferase inhibitors, azacitidine and decitabine, are currently approved for the treatment of myelodysplastic syndrome (MDS). Choosing between these drugs is an important practical issue. In this retrospective study, patients receiving AZA-7d (azacitidine 75 mg/m(2) subcutaneously × 7 days, n = 75) or DEC-5d (decitabine 20 mg/m(2) intravenously × 5 days, n = 74) were compared. The rates of hematologic response ...
Severo Cecília Bittencourt - - 2013
Paracoccidioidomycosis (PCM) is an endemic disease restricted geographically to Latin America. Brazil accounts for about 80 % of the reported cases, and lungs are most frequently affected. A suggestive radiograph of PCM may only be seen late in the course of the disease. At the beginning, it mimics tuberculosis. On the ...
Ohashi Toshimitsu - - 2013
The activation of oncogenic signaling pathways induces the reprogramming of glucose metabolism in tumor cells and increases lactic acid secretion into the tumor microenvironment. This is a well-known characteristic of tumor cells, termed the Warburg effect, and is a candidate target for anti-tumor therapy. Previous reports show that lactic acid ...
Kaplan Celia P - - 2013
PURPOSE: Patient participation in cancer clinical trials is imperative to the advancement of medical science. Physicians play an important role in recruitment by discussing clinical trials with their cancer patients. Patient-physician discussion is influenced by many factors relating to the physician, the patient, and the healthcare system. METHODS: Physicians selected ...
Khazanie Prateeti - - 2013
QUESTION In patients with chronic heart failure, does a 10-year exercise program improve functional capacity and quality of life? METHODS DESIGN Randomized controlled trial. ALLOCATION {Concealed}*.† BLINDING Blinded† ({health care providers, data collectors}*, outcome assessors, data analysts, and {safety committee}*). FOLLOW-UP PERIOD 10 years. SETTING Coronary clubs (nonprofit associations of ...
Rietdijk Svend T - - 2013
Crohn's disease and ulcerative colitis are chronic inflammatory bowel diseases that have been treated with corticosteroids, 5-aminosalicates and thiopurines, but therapeutic options have been broadened with the arrival of anti- tumor necrosis factor (TNF) antibodies. In this article we review the current evidence based approach to inflammatory bowel disease (IBD), ...
Brown William R - - 2013
Microscopic colitis (MC) is characterized by a triad of watery diarrhea, usually normal colonoscopic findings and typical microscopic findings. Two distinct histological forms of MC have been defined: lymphocytic colitis and collagenous colitis, but overlapping features may be present. The incidence of MC appears to be rising, and in some ...
Baysal Ipek - - 2013
Alzheimer's disease (AD) is an irreversible and progressive neurodegenerative disease that is caused by the irreversible loss of neurons in the hippocampus and cortex regions of the brain. Although the molecular mechanism of the disease is still unclear, the deposition of the amyloid beta proteins (senile plaques) in the extracellular ...
Pawar Pravin - - 2013
Topical fluoroquinolones are used in ophthalmology to treat ocular infections. They are bactericidal and inhibit bacterial DNA replication by inhibiting DNA gyrase and topoisomerase. Fluoroquinolones possess two ionizable groups: a carboxylic group (pKa1 = 5.5 - 6.34) and a heterocyclic group (pKa2 = 7.6 - 9.3), in the nucleus, which ...
Rozman Ales - - 2013
BACKGROUND AND OBJECTIVE: Thoracoscopy with a semirigid instrument is a recent technique successfully used for diagnosing pleural diseases. However, there are concerns about the diagnostic adequacy of biopsy samples obtained by semirigid procedures when compared to rigid thoracoscopy. The purpose of this study was to compare the size, quality and ...
Cao Liping - - 2013
iASPP (inhibitory member of the ASPP family), the conserved key inhibitor of p53, is overexpressed and plays an important oncogenetic role in many human cancers. However, its function in cervical cancer remains unknown. The objective of this study was to investigate the expression and clinical relevance of iASPP in cervical ...
Xia Ling - - 2013
Flow counterbalanced capillary electrophoresis (FCCE) offers a powerful approach to realizing difficult charge based separations in compact microchip devices with application of relatively small electrical voltages. The need for dynamically controlling the pressure-gradient in the FCCE column however presents a significant challenge in implementing this technique on the microchip platform. ...
Kim Jeong-Min - - 2013
Moyamoya disease (MMD) is an idiopathic progressive narrowing of distal internal carotid arteries and secondary development of small collaterals.(1) The distinction between MMD and intracranial atherosclerosis is not easy when a patient has concomitant vascular risk factors. We attempted to differentiate the 2 disease conditions by applying high-resolution plaque MRI ...
Wang Y - - 2013
OBJECTIVES: To evaluate the accuracy of volumetric measurement of simulated root resorption cavities based on cone beam computed tomography (CBCT), in comparison with that of Micro-computed tomography (Micro-CT) which served as the reference. SETTING AND SAMPLE POPULATION: The State Key Laboratory of Oral Diseases at Sichuan University. MATERIAL AND METHODS: ...
Stuurman Frederik E - - 2013
The use of oral anticancer drugs has increased during the last decade, because of patient preference, lower costs, proven efficacy, lack of infusion-related inconveniences, and the opportunity to develop chronic treatment regimens. Oral administration of anticancer drugs is, however, often hampered by limited bioavailability of the drug, which is associated ...
Billstedt E - - 2013
OBJECTIVE: Personality traits are presumed to endure over time, but the literature regarding older age is sparse. Furthermore, interpretation may be hampered by the presence of dementia-related personality changes. The aim was to study stability in neuroticism and extraversion in a population sample of women who were followed from mid-life ...
Baggott Matthew J MJ University of Chicago, Chicago, IL, - - 2013
Theobromine, a methylxanthine related to caffeine and present in high levels in cocoa, may contribute to the appeal of chocolate. However, current evidence for this is limited. We conducted a within-subjects placebo-controlled study of a wide range of oral theobromine doses (250, 500, and 1,000 mg) using an active control ...
Di Pietro Fabio - - 2013
Protein Y (PY) is an Escherichia coli cold-shock protein which has been proposed to be responsible for the repression of bulk protein synthesis during cold adaptation. Here, we present in vivo and in vitro data which clarify the role of PY and its mechanism of action. Deletion of yfiA, the ...
Jiao Li L Houston VA Health Services Research and Development Center of Excellence, Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX, USA. - - 2013
Diet is a potentially modifiable risk factor for Barrett's esophagus (BE). We investigated the associations between intakes of fruits and vegetables and risk of BE. We identified study subjects from 1,859 participants who underwent the endoscopy in a single VA Medical Center in the US between 2008 and 2011. Dietary ...
De Clippeleir Haydée - - 2013
Energy-positive sewage treatment can be achieved by implementation of oxygen-limited autotrophic nitrification/denitrification (OLAND) in the main water line, as the latter does not require organic carbon and therefore allows maximum energy recovery through anaerobic digestion of organics. To test the feasibility of mainstream OLAND, the effect of a gradual temperature ...
Patterson P - - 2013
PURPOSE: The current study sought to establish the psychometric properties of the revised Offspring Cancer Needs Instrument (OCNI) when completed by a large sample of young people impacted by parental cancer recruited from multiple settings. METHODS: The psychometric properties were evaluated with 256 young people aged between 12 and 24 ...
Zhang Yan-Jun - - 2013
The purposes of this study were to investigate the effects of B cell translocation gene 2 (BTG2) on the proliferation, apoptosis, and invasion of triple-negative breast cancer and to provide an experimental basis for the future treatment of human triple-negative breast cancer. A pcDNA3.1-BTG2 eukaryotic expression vector was constructed and ...
Ou-Yang Fangqian F Department of Biological Sciences, Texas Tech University, Lubbock, TX 79409-3131, - - 2013
microRNAs (miRNAs) are a class of small RNAs (sRNAs) of ~21 nucleotides (nt) in length processed from foldback hairpins by dicer-like1 (DCL1) or DCL4. They regulate the expression of target mRNAs by base pairing through RNA-induced silencing complex (RISC). In the RISC, Argonaute1 (AGO1) is the key protein that cleaves ...
Berglund Sean P - - 2013
A new dispenser and scanner system is used to create and screen Bi-M-Cu oxide arrays for cathodic photoactivity, where M represents 1 of 22 different transition and post-transition metals. Over 3000 unique Bi : M : Cu atomic ratios are screened. Of the 22 metals tested, 10 show a M-Cu oxide with higher photoactivity ...
Kaila Ville R I - - 2013
Understanding the mechanism of spectral tuning of biological chromophores is a major challenge in photobiology. We show here using large-scale full quantum chemical calculations of the green fluorescent protein that state-of-the-art coupled-cluster calculations provide accurate excitation energies and detailed insight about specific environmental effects. We obtain vertical excitation energies of ...
Jung Sungwon - - 2013
ABSTRACT: BACKGROUND: Identifying similarities and differences in the molecular constitutions of various types of cancer is one of the key challenges in cancer research. The appearances of a cancer depend on complexmolecular interactions, including gene regulatory networks and gene-environment interactions. Thiscomplexity makes it challenging to decipher the molecular origin of ...
Rüdiger Hannes A - - 2013
BACKGROUND: The literature suggests that intraoperative fractures of the greater trochanter and the metaphysis are increased with uncemented stems and the direct anterior approach. This study aims to determine the incidence and assess the functional and radiological outcome after such fractures. METHODS: 484 consecutive total hip replacements (THR) (64 ± 12 years) were ...
Michelson Daniel - - 2013
Evidence-based interventions are often unavailable in everyday clinical settings. This may partly reflect practitioners' assumptions that research evidence does not reflect "real-world" conditions. To examine this further, we systematically assessed the clinical effectiveness of parent management training (PMT) for the treatment of child disruptive behavior across different real-world practice contexts. ...
Rothschild Bruce M - - 2013
Perspectives are in the eye of the beholder and are expanded with increased scrutiny (e.g., magnification). The term "porosity' for macroscopically or radiologically identifiable discontinuity in bone is so variably applied as to be incomprehensible in its meanings. A closer examination of surface discontinuity seems appropriate. Histological and atomic level ...
Khalil Hanan - - 2013
To describe the steps needed for a successful implementation of an e-health programme (the Mobile Wound Care system) in rural Victoria, Australia and to provide recommendations for future e-health initiatives. Wound care is a major burden on the health care system. Optimal wound care was found to be impeded by ...
Roumeliotis Theodoros I - - 2013
A naturally occurring benzofuran derivative, Ebenfuran III (Eb III) was investigated for its antiproliferative effects using the DU-145 prostate cell line. Eb III was isolated from Onobrychis ebenoides of the Leguminosae family, a plant endemic in Central and Southern Greece. We have previously reported that Eb III exerts significant cytotoxic ...
Oh Sun Min - - 2013
Currently, dual-energy X-ray absorptiometry (DXA) is the gold standard for detecting osteoporosis, but is not recommended for general population screening. Therefore, this study aims to develop an osteoporosis risk-assessment model to identify high-risk individuals among Korean postmenopausal women. Data from 1,209 and 1,046 postmenopausal women who participated in the 2009 ...
Palmer Adam C - - 2013
The evolution of antibiotic resistance can now be rapidly tracked with high-throughput technologies for bacterial genotyping and phenotyping. Combined with new approaches to evolve resistance in the laboratory and to characterize clinically evolved resistant pathogens, these methods are revealing the molecular basis and rate of evolution of antibiotic resistance under ...
Anand Richa - - 2013
We inoculated lodgepole pine (Pinus contorta var. latifolia (Dougl.) Engelm.) with Paenibacillus polymyxa P2b-2R, a diazotrophic bacterium previously isolated from internal stem tissue of a naturally regenerating pine seedling to evaluate biological nitrogen fixation and seedling growth promotion by this microorganism. Seedlings generated from pine seed inoculated with strain P2b-2R ...
Hung Lien-Yu - - 2013
Seasonal and novel influenza infections have the potential to cause worldwide pandemics. In order to properly treat infected patients and to limit its spread, a rapid, accurate and automatic influenza diagnostic tool needs to be developed. This study therefore presents a new integrated microfluidic system for the rapid detection of ...
Whitney Heather M - - 2013
Patterns of pigmentation overlying the petal vasculature are common in flowering plants and have been postulated to play a role in pollinator attraction. Previous studies report that such venation patterning is significantly more attractive to bee foragers in the field than ivory or white flowers without veins. To dissect the ...
Wang Shasha - - 2013
A novel label-free colorimetric strategy was reported for sensitive detection of copper ions (Cu(2+)) by using the decelerating etching of gold nanorods (GNRs). H(2)O(2) was employed as the oxidant for corrosion of GNRs, leading to the decrease of the aspect ratio of GNRs. In the absence of Cu(2+), the redox ...
Depta Jeremiah P - - 2013
Objectives: To assess the long-term clinical outcomes associated with treatment of non-left main coronary bifurcation lesions using a modified provisional jailed-balloon technique (JBT). Background: Percutaneous coronary intervention (PCI) of bifurcation lesions is associated with a higher risk of adverse events, including the risk of side branch (SB) loss during main ...
Lastra-Barreira Beatriz - - 2013
The reactivity of compounds [RuCl(2)(η(6)-C(6)H(5)OCH(2)CH(2)OH)(L)] (L = phosphine or phosphite) towards the chloride abstractor AgSbF(6) has been investigated. Thus, the treatment of the triphenylphosphite complex [RuCl(2)(η(6)-C(6)H(5)OCH(2)CH(2)OH){P(OPh)(3)}] with one equivalent of AgSbF(6) gave rise to the formation of the dinuclear dichloro-bridged species [{Ru(μ-Cl)(η(6)-C(6)H(5)OCH(2)CH(2)OH){P(OPh)(3)}}(2)](2+) as the hexafluoroantimonate salt. On the other hand, ...
Jarrin D C - - 2013
Objective:Short sleep duration is recognized as a significant risk factor in childhood obesity; however, the question as to how sleep contributes to the development of obesity remains largely unknown. The majority of pediatric studies have relied on sleep duration as the exclusive measure of sleep; this insular approach may be ...
Duggal Priya P Johns Hopkins University School of Medicine, Baltimore, MD, - - 2013
Chinese translation Hepatitis C virus (HCV) infections occur worldwide and either spontaneously resolve or persist and markedly increase the person's lifetime risk for cirrhosis and hepatocellular carcinoma. Although HCV persistence occurs more often in persons of African ancestry and persons with genetic variants near interleukin-28B (IL-28B), the genetic basis is ...
Halon Agnieszka - - 2013
PURPOSE: The aim of this study was to examine the expression of ERM (ezrin, moesin) and Rho (RhoA, RhoB and Cdc42) proteins in breast cancer (BC) patients and to investigate the relationship between the sub-cellular localisation of these proteins and clinicopathological characteristics and patient survival. METHODS: The expression and specific ...
Ali Mohammad Javed - - 2013
Abstract Aims: To study the efficacy of a new technique of single self-linking silicone stent exclusively in pediatric external dacryocystorhinostomy (DCR) and to report the new use and advantages of endoscopic guidance for the same. Material and methods: Prospective interventional case series, including 11 eyes of ten patients with nasolacrimal ...
Shmeliov Aleksey - - 2013
Structural characterization of 2D nanomaterials is an important step towards their future applications. In this work we carried out imaging and structural analysis of 2D h-BN produced by chemical-exfoliation, emphasizing the stacking order in few-layer sheets. Our analysis, for the first time has shown conclusively that non-bulk stacking can exist ...
Goldenholz Daniel M - - 2013
Coccidioidal meningoencephalitis often carries a poor prognosis.(1) Brain imaging can reveal focal enhancement at the basal cisterns, infarction, and communicating hydrocephalus.(2) A 38-year-old HIV-negative Korean man with a history of CSF- and serum-confirmed coccidioidal meningitis, receiving chronic antifungal therapy, presented with a first generalized tonic-clonic seizure. CSF demonstrated pleomorphic leukocytosis, ...
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