Search Results
Results 451 - 500 of 1922
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Herbers Claudia R - - 2013
A detailed understanding of the adsorption of small molecules or macromolecules to a materials surface is of importance, for example, in the context of material and biomaterial research. Classical atomistic simulations in principle provide microscopic insight in the complex entropic and enthalpic interplay at the interface. However, an application of ...
Liu Da-Yong - - 2013
We investigate the electronic and magnetic properties of K(x)Fe(2-y)Se(2) materials at different band fillings utilizing the multi-orbital Kotliar-Ruckenstein slave boson mean-field approach. We find that the ground state of KFe(2)Se(2) is a paramagnetic (PM) bad metal with intermediate correlation, in contrast with the previous antiferromagnetic (AFM) results obtained by the ...
Moser Gabriele - - 2013
OBJECTIVES:Gut-directed hypnotherapy (GHT) in individual sessions is highly effective in the treatment of irritable bowel syndrome (IBS). This study aimed to assess the long-term effect of GHT in group sessions for refractory IBS.METHODS:A total of 164 patients with IBS (Rome-III-criteria) were screened, and 100 refractory to usual treatment were randomized ...
Ringe Emilie - - 2013
Interest in nanotechnology is driven by the unique and novel properties of nanoscale materials such as the strong interaction of metal particles with light, caused by localized surface plasmon resonances (LSPRs). In this perspective article we review and discuss prominent advantages and advances in single particle studies of plasmonic nanostructures. ...
Yang Chunzhang - - 2013
Astrocytic activation is a cellular response to disturbances of the central nervous system (CNS). Recent advances in cellular and molecular biology have demonstrated the remarkable changes in molecular signaling, morphology, and metabolism that occur during astrocyte activation. Based on these studies, it has become clear that the astrocyte activation process ...
Abbasi Fahim - - 2013
Insulin-mediated glucose disposal varies severalfold in apparently healthy individuals, and approximately one-third of the most insulin resistant of these individuals is at increased risk to develop various adverse clinical syndromes. Since direct measurements of insulin sensitivity are not practical in a clinical setting, several surrogate estimates of insulin action have ...
Lavalleur Heather J - - 2013
Geological carbon sequestration in basalts is a promising solution to mitigate carbon emissions into the Earth's atmosphere. The Wallula pilot well in eastern Washington State, USA provides an opportunity to investigate how native microbial communities in basalts are affected by the injection of supercritical carbon dioxide into deep, alkaline formation ...
Hamada Tsuyoshi - - 2013
BACKGROUND: Early identification of severe cases of acute pancreatitis is necessary to reduce mortality. The Japanese severity score, which consists of nine prognostic factors, is reported to be useful for assessment of acute pancreatitis severity, but has not been validated by large-scale data. METHODS: Data on adult patients with acute ...
Deng Yating - - 2013
Gentiopicroside (GE), a naturally occurring iridoid glycoside, has been developed into a Novel Traditional Chinese Drug named Gentiopicroside injection, and it was approved for the treatment of acute jaundice and chronic active hepatitis by SFDA. However, the inhibitory and inducible effects of GE on the activity of cytochrome P450 (CYP450) ...
Walraven Carl van - - 2013
QUESTION Do health care provider audit and feedback improve compliance with desired practice and patient outcomes? REVIEW SCOPE Included studies assessed the effect of audit and feedback for health care providers responsible for patient care, including those in postgraduate training. Feedback could be recommendations for clinical actions and could be ...
Zhao Chuan - - 2013
Theory suggests that predators of soil-improving, plant-facilitating detritivores (e.g. earthworms) should suppress plant growth via a negative tri-trophic cascade, but the empirical evidence is still largely lacking. We tested this prediction in an alpine meadow on the Tibetan Plateau by manipulating predatory beetles (presence/absence) and quantifying (i) direct effects on ...
Relić Dubravka - - 2013
In this paper, the main objective was fractionation of Cd, Cu, Ni, Pb, Zn, Ca, Fe, and K in certificate material and sediment samples gathered from and around the Petrochemical Industry using the conventional, microwave and ultrasonic sequential extraction. Microwave oven and ultrasound bath were used as an energy source ...
Stuhr-Hansen Nicolai - - 2013
The Fukuyama-Mitsunobu alkylation procedure is widely used to introduce alkyl substituents to amino groups in general and N-alkylation of peptides in particular. Here we have investigated the procedure in detail for N-alkylation of peptides with N-terminal glycine residues, based on the observation that standard conditions lead to substantial bis-nosylation of ...
Chiellini Carolina - - 2013
A pilot-scale membrane bioreactor (MBR) and a conventional activated sludge system (CAS) were in parallel operated to investigate the impact of the separation technology on the structure and functionality of the selected microbial community. Microbial communities as well as nitrogen removal efficiency of the biomass were characterized. Kinetics and microbial ...
Mizoguchi Tadashi - - 2013
The compositions of glycolipids in the following seven strains of green photosynthetic bacteria were investigated at the molecular level using LC-MS coupled with an evaporative light scattering detector: Chlorobium (Chl.) limicola strains Larsen (30 °C as the optimal cultivation temperature) and DSM245 (30 °C), Chlorobaculum (Cba.) tepidum strain ATCC49652 (45 °C), Cba. parvum ...
Kolli Viswa Kalyan - - 2013
PURPOSE: One of the major toxic side effects of methotrexate (MTX) is enterocolitis. To date, there is no efficient standard treatment for this side effect. Nitrosative stress is reported to play a critical role in MTX-induced mucositis. The purpose of this study is to investigate whether pretreatment with melatonin, an ...
Mizukami Amanda - - 2013
The need for efficient and reliable technologies for clinical-scale expansion of mesenchymal stromal cells (MSC) has led to the use of disposable bioreactors and culture systems. Here, we evaluate the expansion of cord blood-derived MSC in a disposable fixed bed culture system. Starting from an initial cell density of 6.0x10(7) ...
Ilhan-Mutlu Aysegül - - 2013
Glioblastoma is the most frequent primary brain tumour in adults. Recent therapeutic advances increased patient's survival, but tumour recurrence inevitably occurs. The pathobiological mechanisms involved in glioblastoma recurrence are still unclear. MicroRNAs are small RNAs proposed o have important roles for cancer including proliferation, aggressiveness and metastases development. There exist ...
Kobayashi Masaaki - - 2013
BACKGROUND: Even after successful Helicobacter pylori eradication, primary or metachronous gastric cancers are sometimes discovered. The endoscopic features of these cancers may be modified by controlling inflammation. Characteristic findings for such lesions in terms of narrow-band imaging with magnifying endoscopy (NBI-ME) and histopathology need to be clarified to allow accurate ...
Bahrs Christian - - 2013
BACKGROUND: Studies that investigated possible associations between the complexity of proximal humeral fractures and patient characteristics are rare. We hypothesized that the grade of fracture complexity may correlate with age and gender of hospitalized, adult patients. METHODS: Based on the Neer classification, we defined four radiological grades of fracture complexity. ...
Aaron Shawn D - - 2013
QUESTION In adults with chronic obstructive pulmonary disease (COPD), how effective are combined inhaled corticosteroid (ICS) plus long-acting β2-agonist (LABA) preparations compared with LABAs alone? REVIEW SCOPE Included studies compared combined ICS plus LABA (ICS/LABA) inhalers (fluticasone and salmeterol [FPS] or budesonide and formoterol [BDF]) with the same LABA alone ...
Kaila Ville R I - - 2013
Understanding the mechanism of spectral tuning of biological chromophores is a major challenge in photobiology. We show here using large-scale full quantum chemical calculations of the green fluorescent protein that state-of-the-art coupled-cluster calculations provide accurate excitation energies and detailed insight about specific environmental effects. We obtain vertical excitation energies of ...
Rüdiger Hannes A - - 2013
BACKGROUND: The literature suggests that intraoperative fractures of the greater trochanter and the metaphysis are increased with uncemented stems and the direct anterior approach. This study aims to determine the incidence and assess the functional and radiological outcome after such fractures. METHODS: 484 consecutive total hip replacements (THR) (64 ± 12 years) were ...
Michelson Daniel - - 2013
Evidence-based interventions are often unavailable in everyday clinical settings. This may partly reflect practitioners' assumptions that research evidence does not reflect "real-world" conditions. To examine this further, we systematically assessed the clinical effectiveness of parent management training (PMT) for the treatment of child disruptive behavior across different real-world practice contexts. ...
Rothschild Bruce M - - 2013
Perspectives are in the eye of the beholder and are expanded with increased scrutiny (e.g., magnification). The term "porosity' for macroscopically or radiologically identifiable discontinuity in bone is so variably applied as to be incomprehensible in its meanings. A closer examination of surface discontinuity seems appropriate. Histological and atomic level ...
Khalil Hanan - - 2013
To describe the steps needed for a successful implementation of an e-health programme (the Mobile Wound Care system) in rural Victoria, Australia and to provide recommendations for future e-health initiatives. Wound care is a major burden on the health care system. Optimal wound care was found to be impeded by ...
Roumeliotis Theodoros I - - 2013
A naturally occurring benzofuran derivative, Ebenfuran III (Eb III) was investigated for its antiproliferative effects using the DU-145 prostate cell line. Eb III was isolated from Onobrychis ebenoides of the Leguminosae family, a plant endemic in Central and Southern Greece. We have previously reported that Eb III exerts significant cytotoxic ...
Oh Sun Min - - 2013
Currently, dual-energy X-ray absorptiometry (DXA) is the gold standard for detecting osteoporosis, but is not recommended for general population screening. Therefore, this study aims to develop an osteoporosis risk-assessment model to identify high-risk individuals among Korean postmenopausal women. Data from 1,209 and 1,046 postmenopausal women who participated in the 2009 ...
Hoffmann Kathryn - - 2013
OBJECTIVE: The aim of this study was to analyse the frequency of C-reactive protein (CRP) rapid test use by general practitioners (GPs), the role of the test in the antibiotic treatment decisions and the efficacy of the test in a primary care setting, with special emphasis on the redemption rate ...
Bomba Monica - - 2013
ABSTRACT: BACKGROUND: Anorexia nervosa commonly arises during adolescence and is associated with more than one medical morbidity. Abnormalities in brain structure (defined as "pseudoatrophy") are common in adolescents with anorexia nervosa; however, their correlations with endocrinological profiles and clinical parameters are still unclear. In particular, no study has described the ...
Banin Luciana Burgugi - - 2013
The present study aims to understand the relation between religious beliefs, physicians' behavior and patients' opinions regarding "Spirituality, religiosity and health (S/R)" issues, and what makes a patient more prone to accept a physician to address his/her spiritual issues. A cross-sectional study was carried out in outpatients from a tertiary ...
Swords Darden C - - 2013
Renal cell carcinoma (RCC) is more common in renal transplant and dialysis patients than the general population. However, RCC in transplanted kidneys is rare, and treatment has previously consisted of nephrectomy with a return to dialysis. There has been recent interest in nephron-sparing procedures as a treatment option for RCC ...
Cabbolet Marcoen J T F - - 2013
Scientific misconduct is usually assumed to be self-serving. This paper, however, proposes to distinguish between two types of scientific misconduct: 'type one scientific misconduct' is self-serving and leads to falsely positive conclusions about one's own work, while 'type two scientific misconduct' is other-harming and leads to falsely negative conclusions about ...
Singh Virendra - - 2013
OBJECTIVES:Splanchnic arterial vasodilatation and subsequent activation of anti-natriuretic and vasoconstrictive mechanisms have an important role in cirrhotic ascites. The aim of this study was to evaluate the effects of midodrine, clonidine, and their combination on systemic hemodynamics, renal function, and control of ascites in patients with cirrhosis and refractory or ...
Dabbouseh Noura M - - 2013
Therapy for hepatitis C has been fairly stagnant for the past decade, but the past few years have seen major progress and evolution, beginning with the approval of two HCV protease inhibitors in 2011. In spite of considerable improvements in response rates with these agents, a need for additional agents ...
Wittink Marsha N - - 2013
BACKGROUND: While 'personalized medicine' commonly refers to genetic markers or profiles associated with pharmacological treatment response, tailoring treatments to patient preferences and values is equally important. OBJECTIVE: To describe and demonstrate a method to develop 'values markers,' or profiles based on the relative importance of attributes of depression treatment. STUDY ...
Beers Erna - - 2013
BACKGROUND: Historically, older patients have been frequently excluded from clinical trials. This has a knock-on effect on the availability of relevant information from trials for health-care professionals prescribing medicines to older individuals in daily clinical practice. OBJECTIVE: To investigate the availability of information relevant to appropriate prescribing for older people ...
Shiraishi Takeshi - - 2013
PURPOSE: Chemoradiation therapy (CRT) is recommended as standard care for stage III non-small cell lung cancer (NSCLC), but some patients experience local recurrence after the treatment. Surgical resection after CRT involves high surgical risk, but is expected to increase the curability. This study was performed to investigate the impact of ...
Billè Andrea - - 2013
We present a case of a 60-year-old woman with a positive fluorodeoxyglucose integrated positron emission tomography and computed tomography (PET/TC) mammary chain lymphadenopathy and carcinoid tumor of the left lower lobe who had a previous bilateral mastectomy and breast reconstruction for breast cancer. She underwent a right muscle sparing mini-thoracotomy ...
Zhou T - - 2013
(75)As nuclear magnetic resonance (NMR) measurements carried out on underdoped, non-superconducting Ca(10)(Pt(3)As(8))(Fe(2)As(2))(5) reveal physical properties that are similar but not identical to 122 superconductor parent compounds such as BaFe(2)As(2). Results from the single crystal study indicate a phase transition to an antiferromagnetic (AF) state on cooling through T ∼ 100 K, albeit nonuniformly. Specifically, the ...
Kim Jeong-Min - - 2013
Moyamoya disease (MMD) is an idiopathic progressive narrowing of distal internal carotid arteries and secondary development of small collaterals.(1) The distinction between MMD and intracranial atherosclerosis is not easy when a patient has concomitant vascular risk factors. We attempted to differentiate the 2 disease conditions by applying high-resolution plaque MRI ...
Wang Y - - 2013
OBJECTIVES: To evaluate the accuracy of volumetric measurement of simulated root resorption cavities based on cone beam computed tomography (CBCT), in comparison with that of Micro-computed tomography (Micro-CT) which served as the reference. SETTING AND SAMPLE POPULATION: The State Key Laboratory of Oral Diseases at Sichuan University. MATERIAL AND METHODS: ...
Stuurman Frederik E - - 2013
The use of oral anticancer drugs has increased during the last decade, because of patient preference, lower costs, proven efficacy, lack of infusion-related inconveniences, and the opportunity to develop chronic treatment regimens. Oral administration of anticancer drugs is, however, often hampered by limited bioavailability of the drug, which is associated ...
Billstedt E - - 2013
OBJECTIVE: Personality traits are presumed to endure over time, but the literature regarding older age is sparse. Furthermore, interpretation may be hampered by the presence of dementia-related personality changes. The aim was to study stability in neuroticism and extraversion in a population sample of women who were followed from mid-life ...
Di Pietro Fabio - - 2013
Protein Y (PY) is an Escherichia coli cold-shock protein which has been proposed to be responsible for the repression of bulk protein synthesis during cold adaptation. Here, we present in vivo and in vitro data which clarify the role of PY and its mechanism of action. Deletion of yfiA, the ...
Anand Richa - - 2013
We inoculated lodgepole pine (Pinus contorta var. latifolia (Dougl.) Engelm.) with Paenibacillus polymyxa P2b-2R, a diazotrophic bacterium previously isolated from internal stem tissue of a naturally regenerating pine seedling to evaluate biological nitrogen fixation and seedling growth promotion by this microorganism. Seedlings generated from pine seed inoculated with strain P2b-2R ...
Hung Lien-Yu - - 2013
Seasonal and novel influenza infections have the potential to cause worldwide pandemics. In order to properly treat infected patients and to limit its spread, a rapid, accurate and automatic influenza diagnostic tool needs to be developed. This study therefore presents a new integrated microfluidic system for the rapid detection of ...
Whitney Heather M - - 2013
Patterns of pigmentation overlying the petal vasculature are common in flowering plants and have been postulated to play a role in pollinator attraction. Previous studies report that such venation patterning is significantly more attractive to bee foragers in the field than ivory or white flowers without veins. To dissect the ...
Wang Shasha - - 2013
A novel label-free colorimetric strategy was reported for sensitive detection of copper ions (Cu(2+)) by using the decelerating etching of gold nanorods (GNRs). H(2)O(2) was employed as the oxidant for corrosion of GNRs, leading to the decrease of the aspect ratio of GNRs. In the absence of Cu(2+), the redox ...
Depta Jeremiah P - - 2013
Objectives: To assess the long-term clinical outcomes associated with treatment of non-left main coronary bifurcation lesions using a modified provisional jailed-balloon technique (JBT). Background: Percutaneous coronary intervention (PCI) of bifurcation lesions is associated with a higher risk of adverse events, including the risk of side branch (SB) loss during main ...
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