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Results 401 - 450 of 4303
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Marina Michel - - 2013
Abstract The objective of this study was to confirm whether gymnastics practice from a young age can induce greater vertical jump reliability. Fifty young female gymnasts (8.84 ± 0.62 years) and 42 females in the control group (8.58 ± 0.92 years) performed the following jump tests on a contact mat: squat jump, countermovement jump, ...
Qualls Kathlene K - - 2013
ABSTRACT The purpose of this case report was to describe the use of the Nintendo® Wii Fit Plus as an alternative exercise for an 11-year-old child with primary Raynaud's disease (PRD) and obesity who was not involved in organized sports and had limited outdoor physical activity and exercise. The Wii ...
Laakso Sanna - - 2013
Sepsis is associated with high morbidity and mortality rates worldwide. Rapid and reliable diagnostic methods are needed for efficient and evidence-based treatment of septic patients. Recently, new molecular tools have emerged to complement the conventional culture-based diagnostic methods. In this study, we used spiked whole blood samples to evaluate together ...
Chan Sunney I - - 2013
TONs of copper fun: There is considerable interest in developing catalysts to harness the abundant natural supply of methane for various industrial applications. Two tricopper complexes capable of mediating efficient oxidation of methane to methanol under ambient conditions were tested: a biomimetic tricopper complex and a tricopper-peptide species derived from ...
Bastakoti Bishnu Prasad - - 2013
We have developed core-shell-corona-type polymeric micelles that can integrate multiple functions in one system, including the capability of accommodating hydrophobic dyes into core and hydrophilic drug into the shell, as well as pH-triggered drug-release. The neutral and hydrophilic corona sterically stabilizes the multifunctional polymeric micelles in aqueous solution. The mineralization ...
Seitz Miriam - - 2013
Promiscuous enzymes: The substrate promiscuity of squalene-hopene cyclases has been explored and applied in the enzyme-catalyzed synthesis of heterocyclic terpenoids. Features of this work include cyclization reactions without pyrophosphate activation, and stereospecific ring closure of substrates of varying chain length and terminal nucleophile. This provides a biocatalytic alternative to traditional ...
Schéle Erik - - 2013
Interleukin-1 (IL-1) and interleukin-6 (IL-6) are immune modulating cytokines that also affect metabolic functions, as both IL-1 receptor I deficient (IL1RI -/-) and IL-6 deficient (IL-6 -/-) mice develop late-onset obesity and leptin resistance. Both IL-1 and IL-6 appear to target the central nervous system (CNS) to increase energy expenditure. ...
Zupan Jure - - 2013
At high cell density or under low nutrient conditions, yeast collectively adapt their metabolism by secreting aromatic alcohols in what is known as quorum sensing. However, the mechanisms and role of quorum sensing in yeast are poorly understood, and the methodology behind this process is not well established. Here, we ...
Valdés Alberto - - 2013
Nowadays, new solutions focused on the replacement of reagents hazardous to human health are highly demanded in laboratories and Green Chemistry. In the present work, GelGreen, a new non-hazardous DNA staining reagent, has been assayed for the first time to analyze double-stranded DNA by capillary gel electrophoresis (CGE) with laser ...
Cao Xuefei - - 2013
Traditionally, long reaction time was required in the synthesis of cellulose esters (CEs). In this work, DMSO/aqueous NaOH or KOH was introduced as an efficient reaction system for rapidly synthesizing CEs by transesterification. Interesingly, cellulose could rapidly reacted with vinyl acetate, vinyl propionate, and vinyl butyrate and synthesized cellulose acetate, ...
Vallar Giuseppe - - 2013
OBJECTIVE.: To assess the role of the superior longitudinal fascicle, the inferior fronto-occipital fascicle, and the posterior parietal lobe in visuospatial attention in humans during awake brain surgery. EXPERIMENTAL DESIGN.: Seven patients with hemispheric gliomas (six in the right hemisphere) entered the study. During surgery in asleep/awake anesthesia, guided by ...
Brinkhaus Linda - - 2013
In contrast to pristine zinc phthalocyanine (1), zinc phthalocyanine based oPPV-oligomers (2-4) of different chain lengths interact tightly and reversibly with graphite, affording stable and finely dispersed suspensions of mono- to few-layer graphene-nanographene (NG)-that are photoactive. The p-type character of the oPPV backbones and the increasing length of the oPPV ...
Misago Noriyuki - - 2013
The terminology and classification of keratoacanthoma (KA) and other types of squamous cell carcinoma (SCC) with crateriform architecture have not been clarified. The study evaluated the clinicopathological features of 41 nodular (exo-endophytic) SCC lesions with a central keratin-filled crater, including KA (well-developed stage). The lesions were histopathologically classified into six ...
Dawson A J - - 2013
Biological variation refers to the natural fluctuations found when repeated measurements are made in a biological system. Generally, biological variation remains within narrow boundaries in health, but may differ in pathological states, with implications for the diagnosis and monitoring of disease processes. In disease, biological variation may alter such that ...
Duvoux Christophe - - 2013
Recurrence of hepatitis C virus infection following liver transplantation (LT) for hepatitis C is universal. After LT, hepatitis C is associated with accelerated fibrosis progression and reduced graft and patient survival. Furthermore, responses to antiviral therapy in patients with recurrent hepatitis C virus post-transplant are consistently sub-optimal. Calcineurin inhibitors (CNIs) ...
Levinson Rebecca T - - 2013
Light chain (AL) amyloidosis is characterized by the misfolding of immunoglobulin light chains, accumulating as amyloid fibrils in vital organs. Multiple reports have indicated that amyloidogenic light chains internalize into a variety of cell types, but these studies used urine-derived proteins without indicating any protein sequence information. As a result, ...
Yang Tao - - 2013
The mitotic kinesin superfamily protein KIF14 is essential for cytokinesis and chromosome segregation and increased KIF14 expression is related to a variety of human cancers. In this study, we investigate KIF14 expression in association with clinical variables and the role of KIF14 during tumorigenesis. We found that KIF14 is overexpressed ...
Wen Yu-Guan - - 2013
OBJECTIVE: The aim of the study was to better understand blonanserin population pharmacokinetic (PK) characteristics in Chinese healthy subjects. METHODS: Data from two studies with 50 subjects were analyzed to investigate the population PK characteristics of blonanserin at single dose (4, 8, and 12 mg) under fasting, multidose (4 mg bid or ...
Wong G W K - - 2013
BACKGROUND: We conducted Phase 2 of the Asthma Insights and Reality in the Asia-Pacific (AIRIAP 2) survey in 2006 to determine the level of asthma control in this region and the validity of the Asthma Control Test™ (ACT) and childhood ACT (C-ACT) in relation to asthma control. METHODS: Pediatric participants ...
Chávez J - - 2013
BACKGROUND: Nucleotides released to the extracellular space stimulate purinergic receptors, and their effects are modulated by ectonucleotidases. The role of ATP in the allergic bronchospasm has been scantly studied. METHODS: We used several techniques (plethysmography, organ baths, confocal microscopy, RT-PCR, ATP measurement) to explore the role of nucleotides and ectonucleotidases ...
Jayapalan Jaime Jacqueline - - 2013
The present study was aimed at the identification of proteins that are differentially expressed in the urine of patients with prostate cancer (PCa), those with benign prostatic hyperplasia (BPH) and age-matched healthy male control subjects. Using a combination of two-dimensional gel electrophoresis and tandem mass spectrometry, significantly lower expression of ...
Scazzina Francesca - - 2013
As bread is the most relevant source of available carbohydrates in the diet and as lowering dietary glycaemic index (GI) is considered favourable to health, many studies have been carried out in order to decrease the GI of bread. The most relevant strategy that has been applied so far is ...
Hou Shuangxing - - 2013
ABSTRACT: BACKGROUND: Lead is a heavy metal and important environmental toxicant and nerve poison that can destruction many functions of the nervous system. Lead poisoning is a medical condition caused by increased levels of lead in the body. Lead interferes with a variety of body processes and is toxic to ...
Aizawa J - - 2013
Morphological studies of the gastrointestinal tract of blue-and-yellow macaws (Ara ararauna) are scarce. In view of the paucity of information regarding the digestive tract of macaws, this study aims to describe the gross anatomical features (oesophagus to cloaca) as part of a broad study of the gastrointestinal tract (GIT) of ...
Gan Qiaoqiang - - 2013
Recent advances in molecular organic photovoltaics (OPVs) have shown 10% power conversion efficiency (PCE) for single-junction cells, which put them in direct competition with PVs based on amorphous silicon. Incorporation of plasmonic nanostructures for light trapping in these thin-film devices offers an attractive solution to realize higher-efficiency OPVs with PCE≫10%. ...
Kennedy David C - - 2013
Carbohydrates on cell surfaces are critical components of the extracellular landscape and contribute to cell signalling, motility, adhesion and recognition. Multivalent effects are essential to these interactions that are inherently weak. Carbohydrate-functionalised surfaces meet an important need for studying the multivalent interactions between carbohydrates and other biomolecules. Innovations in nanomaterials ...
Qin Hui - - 2013
We have developed a synergic micro-extraction procedure based on ionic liquid for the preconcentration and determination of glucocorticoids in water samples. Using non-ionic surfactant Triton X-100 (TX-100) as synergic reagent, 1-butyl-3-methylimidazolium hexafluorophosphate ([BMIM]PF(6) ) accomplished extraction rapidly without heating in water bath. One key property of ionic liquids that highlights ...
Wang Hui-Ping - - 2013
Anticholinesterase pesticides have been widely used in agricultural and domestic settings and can be detected in the environment after long-term use. Although the acute toxic effects of chlorpyrifos and carbaryl have been well described, little is known about the chronic toxicity of the pesticides mixture. To investigate their chronic neurotoxicity, ...
Jin Zhengzhong - - 2013
Soil microbes in forest land are crucial to soil development in extreme areas. In this study, methods of conventional culture, PLFA and PCR-DGGE were utilized to analyze soil microbial quantity, fatty acids and microbial DNA segments of soils subjected to different site conditions in the Tarim Desert Highway forest land. ...
Amador Fernando J - - 2013
Ryanodine Receptors (RyRs) are the largest known ion channels. They are Ca(2+) -release channels found primarily on the sarcoplasmic reticulum (SR) of myocytes. Several hundred mutations in RyRs are associated with skeletal or cardiomyocyte disease in humans. Many of these mutations can now be mapped onto the high-resolution structures of ...
Cao Shan - - 2013
Diatom settlement and cell division is important in two major aspects. Firstly, biofouling is a costly problem in the shipping industry that necessitates the effective inhibition of diatom settlement and proliferation. Secondly, biological coatings on the basis of ordered and densely packed cell lawns of diatom are useful for nano- ...
Grzybowski Andrzej - - 2013
In an era of scientific method, precision of nomenclature and an electronically accessible publication record, the early history of keratoconus still remains, in parts, as complex and perplexing as the disease itself. Historically, the disease has been somewhat confusingly referred to by several different terms, including hyperkeratosis, ochlodes, conical formed ...
Sun Jintang - - 2013
Osteopontin (OPN), a multifunctional glycoprotein, has three transcripts that have distinct roles in tumors in vitro. Whether OPN transcripts have different functions in tumor processes in vivo is unclear. It has been reported that immune cell-derived OPN can promote tumor formation. We propose a hypothesis that tumor-derived OPN may facilitate ...
Buncke Gregory - - 2013
PURPOSE: Ultrasound (US) has been used in the management of carpal tunnel syndrome since the 1980s. The first report of US-guided carpal tunnel release (CTR) was published in 1997, with cadaver and clinical reports confirming the safe navigation of surgical tools with US for division of the transverse carpal ligament. ...
Diederich François - - 2013
This Review investigates the development of Angewandte Chemie since the founding of the journal in 1887 and analyzes how its content reflects the changes in chemical research over these 125 years. Although Angewandte Chemie was originally founded as a journal for applied ("angewandte")-technical and analytical-chemistry, numerous review articles and abstracts ...
Yao Jiaqi - - 2013
PURPOSE: A number of studies have shown that the levels of some proteins in the aqueous humor (AH) are altered and correlate with the mechanisms or prognosis of many eye diseases. To identify the possible mechanisms that lead to the development of wet age-related macular degeneration (AMD), a proteomic analysis ...
Sripa Pattrawan - - 2013
An ONIOM-XS MD simulation has been performed to characterize the "structure-making" ability of Na(+) in dilute aqueous solution. The region of most interest, i.e., a sphere that includes Na(+) and its surrounding water molecules, was treated at the HF level of accuracy using LANL2DZ and DZP basis sets for the ...
Sessolo Michele - - 2013
A simple and versatile fabrication process is used to define conducting polymer microelectrode arrays (MEAs), patterning at the same time the recording electrodes as well as the insulating layer. Thanks to the low impedance of poly(3,4-ethylenedioxythiophene)-poly(styrenesulfonate) (PEDOT:PSS) electrodes, these MEAs allow in vitro recording of action potentials from rat hippocampus ...
Schneebeli Severin T - - 2013
We announce the establishment of a new family of macrocycles-the asararenes, which are based on para-methylene linked "asarol methyl ether" (1,2,4,5-tetramethoxybenzene) units. Macrocycles with 6-12 aromatic units have been synthesized and isolated in a single step from asarol methyl ether and paraformaldehyde. Even larger rings, with up to 15 asarol ...
Qiao Yu Qi - - 2013
METHODS: Tumor necrosis factor receptor associated factor-1 (TRAF-1) and TRAF-2 are involved in TNF-α/TNF-R signaling pathways. This study aimed to investigate the expression of TRAF-1 and TRAF-2 in inflammatory bowel disease (IBD) patients. OBJECTIVE: Immunostaining, Western blot and Real-time polymerase chain reaction (PCR) were used to detect the expression of ...
Duša Filip - - 2013
The paper presents a new concept of preparative solution isoelectric focusing (sIEF) where time requirements and efficiency are similar to gel based IEF whereas simple fraction handling as well as quick and complete protein recovery typical for solution based IEF methods are maintained. The presented method is based on the ...
Park Moo Yong - - 2013
BACKGROUND: Acute kidney injury (AKI) is a frequent complication in critically ill patients and is associated with a high mortality. Clinicians have limited tools to predict the course of AKI at the time of serum creatinine increase. We evaluated the diagnostic and prognostic utility of urinary cystatin C (uCysC) in ...
Walczynski J - - 2013
Transcription factors ATF2 (activating transcription factor 2) and ATF7 (activating transcription factor 7) are highly homologous members of the activator protein 1 (AP-1) family. Their activities are growth factor and stress stimulated and they strictly require phosphorylation by mitogen-activated protein (MAP) kinases for their transcriptional functions. In samples of human ...
Freeman Richard B - - 2013
As the pressure for providing liver transplantation to more and more candidates increases, transplant programs have begun to consider deceased donor characteristics that were previously considered unacceptable. With this trend, attention has focused on better defining those donor factors that can impact the outcome of liver transplantation. This review examines ...
Drewe J A - - 2013
Animal health surveillance programmes may change in response to altering requirements or perceived weaknesses but are seldom subjected to any formal evaluation to ensure that they provide valuable information in an efficient manner. The literature on the evaluation of animal health surveillance systems is sparse, and those that are published ...
Tay Louis - - 2013
In light of recent interest in societal subjective well-being, policies that seek to improve the economy and labor markets need to address the question of whether economic factors matter for worker well-being, specifically job satisfaction. In a worldwide representative poll of 136 nations, economic factors are associated with job satisfaction ...
Yeo Samuel Chao Ming - - 2013
SCOPE: Pterostilbene (trans-3,5-dimethoxy-4'-hydroxystilbene, PTS) possesses various health-promoting effects. This study aimed to investigate the impacts of aqueous solubility, fasting, dose escalation, and dosing route on its bioavailability in Sprague-Dawley rats. METHODS AND RESULTS: Upon intravenous administration (2.5 mg/kg), PTS had rapid clearance (Cl = 68.2 ± 9.8 mL/min/kg) and moderate ...
Mishra Arabinda - - 2013
The overall goal of this work is to demonstrate how resting state functional magnetic resonance imaging (fMRI) signals may be used to objectively parcellate functionally heterogeneous subregions of the human amygdala into structures characterized by similar patterns of functional connectivity. We hypothesize that similarity of functional connectivity of subregions with ...
Lin Huandong - - 2013
OBJECTIVE: To evaluate the new DXA VAT method on an Asian Chinese population by comparing to a reference method, computed tomography (CT). DESIGN AND METHODS: In total, 145 adult men and women volunteers, representing a wide range of ages (19 to 83 years) and BMI values (18.5 to 39.3 kg/m(2) ...
Na Kyoung-Sae - - 2013
OBJECTIVE: This study assessed whether the subjective experience of patients with schizophrenia improved after switching from an oral antipsychotic to flexibly-dosed paliperidone extended-release. METHODS: We conducted a 24-week, multicenter, non-comparative, open-label trial. A total of 387 patients with schizophrenia participated the study. The primary study outcome was the change in ...
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