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Konstantinidou Valentini - - 2013
The present review discusses and summarizes the up-to-date body of knowledge concerning human nutrigenomic studies with Mediterranean diet (MedDiet) and olive oil (OO) interventions, at real-life doses and conditions. A literature review was carried out until March 2012. Original articles assessing the nutrigenomic effect of the MedDiet and its main ...
Matsumoto Yuka - - 2013
Biologics such as tumor necrosis factor (TNF) inhibitors are highly effective for treating severe psoriasis, and an increasing number of patients benefit from them. However, subsidiary subjects have arisen in the course of treatment which may directly impact the continued use of these drugs in a given case. In this ...
Zhao Qian - - 2013
Organoclays are highly sorptive engineered materials that can be used as amendments in barrier systems or geosynthetic liners. The performance of confining and isolating the non-polar organic contaminants by those barrier/lining systems is essentially controlled by the process of organic contaminant mass transport in nano-pore of organoclays. In this paper, ...
Kim Hun Young - - 2013
Synthesizing the synthons: The development of α-acylvinyl anion synthons has been achieved using direct α-vinyl enolization of α,β-unsaturated ketones under mild reaction conditions. The synthetic utility of such synthons has been demonstrated in intermolecular aldol and aldol condensation reactions, which provide synthetically useful allenyl ketone and enyne derivatives.
Ceylan Cavit - - 2013
Objectives: To show renal parenchymal injury depending on extracorporeal shock wave lithotripsy (ESWL). Methods: The patients with one renal stone and in whom ESWL is planned among the patients in whom renal stone was determined. Their 24-h urine samples were collected just before and after the ESWL treatment. Cit (citrate), ...
Hu Zhi-peng ZP Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University, Shanghai 200433, - - 2013
ΦC31 integrase mediates site-specific recombination between two short sequences, attP and attB, in phage and bacterial genomes, which is a promising tool in gene regulation-based therapy since the zinc finger structure is probably the DNA recognizing domain that can further be engineered. The aim of this study was to screen ...
Chang Soeun - - 2013
Here we report a tracking X-ray microscopy (TrXM) as a novel methodology by using upper right lung apices alveoli in live intact mice. By enabling tracking of individual alveolar movements during respiration, TrXM identifies alveolar dynamics: individual alveoli in the upper lung apices show a small size increment as 4.9 ...
Hienzsch Antje - - 2013
We report an efficient synthesis of the hypermodified natural tRNA modifications wybutosine (yW) and hydroxywybutosine (OHyW). We also describe the preparation of isotopically labeled analogues for precise quantification of yW and OHyW in different tissues including plant materials. The synthesis involved the formation of the unusual tricyclic ring structure of ...
Gao Qianqian - - 2013
Free fatty acids are typically activated by thioesterification processes and catalyzed by the fatty acyl-CoA synthetase or fatty acyl-ACP synthetase. However, the routes for fatty acid activation in cyanobacteria are not well understood. In this investigation, the slr1609 gene, which encodes the fatty acid activation enzyme, was cloned from Synechocystis ...
Sun Kang - - 2013
To control interactions between cells and nanomaterials has been a great challenge because numerous nanomaterials have been intensively explored in the fields of biology and medicine. However, current surface modification of nanomaterials is mainly carried out in an empirical way. Herein, a general strategy to tune the surface chemistry of ...
Altschuler Eric Lewin - - 2013
The Homeric epics are among the greatest masterpieces of literature, but when they were produced is not known with certainty. Here we apply evolutionary-linguistic phylogenetic statistical methods to differences in Homeric, Modern Greek and ancient Hittite vocabulary items to estimate a date of approximately 710-760 BCE for these great works. ...
García-Resúa Carlos - - 2013
BACKGROUND: Non-contact Tonopachy NT-530P (Nidek Co., LTD) provides intraocular pressure (IOP) and central corneal thickness (CCT) measurements. This study assesses the reliability and repeatability of its IOP measurements in young healthy adult subjects. METHODS: IOP was determined in the right eye of 64 healthy patients using Tonopachy followed by the ...
Armshaw Patricia - - 2013
ICE R391, a prototype member of the SXT/R391 family of site-specific integrative conjugative elements (ICEs), frequently isolated from enterobacterial pathogens, exhibits an unusual, recA-dependent, UV-inducible, cell-sensitising function. This significantly decreases post-irradiation cell survival rates in Escherichia coli host cells, a trait that would at first appear to be counterproductive in ...
Fanin M - - 2013
AIMS: The peculiar clinical features and the pathogenic mechanism related to calpain-3 deficiency (impaired sarcomere remodelling), suggest that the ubiquitin-proteasome degradation pathway may have a crucial role in Limb-Girdle Muscular Dystrophy 2A (LGMD2A). We therefore investigated muscle atrophy and the role of the ubiquitin-proteasome and lysosomal-autophagic degradation pathways. METHODS: We ...
El Deeb Sami - - 2013
The review gives an update about the methodological and instrumental developments in micellar electrokinetic chromatography as a type of capillary electrophoresis analytical technique. Here, the last two years development of the technique are particularly presented. Recent approaches to improve sensitivity are discussed. Newly introduced concentration techniques and experimental methods for ...
Wang Mao - - 2013
Single and large-area aligned crystalline microribbons of 6,13-dichloropentacene (DCP) are prepared. The ribbons display excellent charge transport properties with a mobility of up to 9.0 cm(2) V(-1) s(-1) in ambient conditions, one of the highest values reported for organic semiconductors. The slipped π-π stacking with large intermolecular overlap is responsible ...
Takahashi Hidetoshi - - 2013
We compared the clinical efficacy of various psoriasis treatments among: (i) topical application of calcipotriol ointment twice daily (group I); (ii) topical application of calcipotriol ointment twice daily and narrowband ultraviolet B NB-UVB phototherapy once a week (group II); (iii) topical application of heparinoid ointment twice daily and NB-UVB phototherapy ...
Kwong L N - - 2013
The treatment of melanoma, the most aggressive form of skin cancer, is being revolutionized by the development of personalized targeted therapy approaches. Mutant-selective BRAF inhibitors and MEK inhibitors have demonstrated impressive clinical results in molecularly selected patients. However, emerging understanding of the molecular heterogeneity of this disease and the identification ...
Cai Yuqun - - 2013
There are two major classes of neurons in nervous systems: projection neurons and interneurons. During Drosophila nervous system development, a subpopulation of individual stem/progenitor cells gives rise to both motor neurons and interneurons. However, it remains unknown whether individual stem/progenitor cells in the mammalian brain also have the potential to ...
Hansen Anne A School of Chemistry, University of Edinburgh, Joseph Black Building, West Mains Road, Edinburgh EH93JJ, - - 2013
Primary human megakaryocytes, the precursor cells of platelets, are difficult to collect and cultivate. Polymers that enrich these cells without affecting their regulation or function are of interest for basic research as well as for cord blood transplantation purposes since co-transplantation of enriched megakaryocyte concentrates increase the success of stem ...
Jin Liji - - 2013
In this paper, the anti-depressant effects of Acanthopanax senticosus extract (ASE) were studied using animal models of depression including the forced swimming and tail suspension tests. The anti-depressive mechanism of ASE was explored by monitoring the levels of monoamine neurotransmitters including 5-hydroxytrylamine (5-HT), norepinephrine (NE), and dopamine (DA), as well ...
Shao Jingjin - - 2013
OBJECTIVE: With the dramatic changes in Chinese society and economy, the average depressive symptoms of Chinese older adults might have changed across their birth cohort. This study aims to examine the changes in the depressive symptoms of Chinese older adults by analyzing data from 1987 to 2010. METHODS: The study ...
Wittenberg James B - - 2013
Climbing the cucurbit ladder: Cucurbit[6]uril dimers (connected gray cylinders; see scheme) were prepared by condensation of glycoluril hexamer with the appropriate tetraaldehydes. The self-assembly process between these dimers and oligoviologen compounds (blue) in water leads to a supramolecular ladder with the dimensions and molecular weight typical of small proteins.
Wolford Matthew F - - 2013
A catalyst free approach for nitrogen oxides (NO(x)) removal has been developed at the United States Naval Research Laboratory. Our goals were to assess the ability of pulsed electron beam to enhance NO(x) removal at potential lower capital cost with greater efficiency than other large scale NO(x) removal methods. Removal ...
Yang Dongjiang D College of Chemistry, Chemical and Environmental Engineering, Laboratory of Fiber Materials and Modern Textile, Qingdao University, Qingdao 266071, P.R. China. - - 2013
Cerium ions (Ce(3+)) can be selectively doped into the TiO2(B) core of TiO2(B)/anatase core-shell nanofibers by means of a simple one-pot hydrothermal treatment of a starting material of hydrogen trititanate (H2Ti3O7) nanofibers. These Ce(3+) ions (≈0.202 nm) are located on the (110) lattice planes of the TiO2(B) core in tunnels ...
Chabaud Stéphane - - 2013
The time needed to produce engineered tissue is critical. A self-assembly approach provided excellent results regarding biological functions and cell differentiation because it closely respected the microenvironment of cells. Nevertheless, the technique was time consuming for producing tissue equivalents with enough extracellular matrix to allow manipulations. Unlike L-arginine supplementation that ...
Hitzbleck Martina - - 2013
Flock-based microfluidics are created by depositing hydrophilic microfibers on an adhesive-coated substrate using an electric field. This enables the fabrication of self-powered microfluidics from one or more different kinds of fibers that form 2D and 3D flowpaths, which can wick 40 microliters of liquid per square centimeter. With this approach, ...
Kole Goutam Kumar - - 2013
An attempt has been made to design double-stranded ladder-like coordination polymers (CPs) of hemidirected Pb(II) . Four CPs, [Pb(μ-bpe)(O(2) C-C(6) H(5) )(2) ]⋅2H(2) O (1), [Pb(2) (μ-bpe)(2) (μ-O(2) C-C(6) H(5) )(2) (O(2) C-C(6) H(5) )(2) ] (2), [Pb(2) (μ-bpe)(2) (μ-O(2) C-p-Tol)(2) (O(2) C-p-Tol)(2) ]⋅ 1.5 H(2) O (3) and [Pb(2) (μ-bpe)(2) ...
Zheng Cai-Jun - - 2013
The exact hosts for F-P hybrid WOLEDs have been first demonstrated following a new design strategy for blue fluorophors with small singlet-triplet splitting. Two novel compounds DPMC and DAPSF exhibit efficient blue fluorescence, high triplet energies and good conductivities. These merits allow us to use new simplified device designs to ...
Sacchetti Cristiano - - 2013
The investigation of nanoparticle protein corona, the shell of plasma proteins formed around nanoparticles immediately after they enter the bloodstream, is a benchmark in the study of the applications of nanoparticles in all fields of medicine, from pharmacology to toxicology. We report the first investigation of the protein corona adsorbed ...
Kucukgoz Gulec Umran - - 2013
Abstract Objective: To compare clinical and laboratory findings between the early-onset preeclampsia (EOP) and late-onset preeclampsia (LOP). Methods: This prospective longitudinal study was performed at a tertiary referral university clinic. All patients meeting the inclusion criteria were divided into two groups, the EOP group and the LOP group, according to ...
Tognetti Celia - - 2013
Xanthophyllomyces dendrorhous (Phaffia rhodozyma) yeasts are biotechnologically exploited as a natural source of astaxanthin for aquaculture. Based on results of recent studies, it has become clear that this species possesses a greater genetic variability generating the necessity to uncover it and assess its potential for the astaxanthin industry. However, difficulties ...
Lin Yi-Feng - - 2013
The use of a membrane contactor combined with a hydrophobic porous membrane and an amine absorbent has attracted considerable attention for the capture of CO(2) because of its extensive use, low operational costs, and low energy consumption. The hydrophobic porous membrane interface prevents the passage of the amine absorbent but ...
Varga Norbert - - 2013
Dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin (DC-SIGN) and Langerin are C-type lectins of dendritic cells (DCs) that share a specificity for mannose and are involved in pathogen recognition. HIV is known to use DC-SIGN on DCs to facilitate transinfection of T-cells. Langerin, on the contrary, contributes to virus elimination; therefore, ...
Zheng Zhong - - 2013
The spectrum of cognitive symptoms in Parkinson's disease (PD) can span various domains, including executive function, language, attention, memory, and visuospatial skills. These symptoms may be attributable to the degradation of projection fibers associated with the underlying neurodegenerative process. The primary purpose of this study is to find microstructural correlates ...
Júlíusson Pétur B - - 2013
Background: Previous growth references for Norwegian children were based on measurements from the 1970s and 1980s. New reference data, collected through the Bergen Growth Study and the Medical Birth Registry of Norway, are presented as LMS values. Materials and methods: A cross-sectional sample of children aged 0-19 years in stratified ...
Efficace F - - 2013
Health-related quality of life (HRQOL) is an important goal of therapy for chronic myeloid leukemia (CML) patients treated with current molecular-targeted therapies. The main objective of this study was to investigate factors associated with long-term HRQOL outcomes of CML patients receiving imatinib. Analysis was performed on 422 CML patients recruited ...
Tang J J Department of Biochemistry and Molecular Biology, Institute of Bioinformatics, University of Georgia, Athens, GA, - - 2014
Herein we report a proof-of-principle study illustrating a novel dog-human comparison strategy that addresses a central aim of cancer research, namely cancer driver-passenger distinction. We previously demonstrated that sporadic canine colorectal cancers (CRCs) share similar molecular pathogenesis mechanisms as their human counterparts. In this study, we compared the genome-wide copy ...
Mooijaart Simon P - - 2013
BACKGROUND: Inflammation is involved in the pathogenesis of cardiovascular disease and cognitive decline. Interleukin 6 (IL-6) has a role in cardiovascular disease but the association of IL-6 concentration and the functional IL6 -174 polymorphism with cognitive decline has not been demonstrated unequivocally. The objective of the present study was to ...
Buncke Gregory - - 2013
PURPOSE: Ultrasound (US) has been used in the management of carpal tunnel syndrome since the 1980s. The first report of US-guided carpal tunnel release (CTR) was published in 1997, with cadaver and clinical reports confirming the safe navigation of surgical tools with US for division of the transverse carpal ligament. ...
Diederich François - - 2013
This Review investigates the development of Angewandte Chemie since the founding of the journal in 1887 and analyzes how its content reflects the changes in chemical research over these 125 years. Although Angewandte Chemie was originally founded as a journal for applied ("angewandte")-technical and analytical-chemistry, numerous review articles and abstracts ...
Yao Jiaqi - - 2013
PURPOSE: A number of studies have shown that the levels of some proteins in the aqueous humor (AH) are altered and correlate with the mechanisms or prognosis of many eye diseases. To identify the possible mechanisms that lead to the development of wet age-related macular degeneration (AMD), a proteomic analysis ...
Sripa Pattrawan - - 2013
An ONIOM-XS MD simulation has been performed to characterize the "structure-making" ability of Na(+) in dilute aqueous solution. The region of most interest, i.e., a sphere that includes Na(+) and its surrounding water molecules, was treated at the HF level of accuracy using LANL2DZ and DZP basis sets for the ...
Zhao Lingguo - - 2013
Hydrophobically modified quaternized celluloses (HMQCs), containing the quaternary ammonium groups and hexadecyl groups, were homogeneously synthesized as novel dynamic coatings for capillary electrophoresis. Compared with quaternized cellulose coating, HMQC coating is able to generate stronger reversed electroosmotic flow (ca. 10% increase) and has better efficiency in suppressing protein adsorption. The ...
Husbands Winston - - 2013
In this study of Black gay and bisexual men in Toronto, sexually active survey participants reported on their sexual behaviours with male partners of different ethnoracial backgrounds, and interview participants reflected on how their sexual relationships emerged in the context of race and interracial desire. Most survey participants reported sexual ...
Botosoa Eliot Patrick - - 2013
In the present study, sponge cakes, produced at the pilot scale, were monitored during ageing (i.e., 1, 3, 6, 9, 16, and 20 days) by three different analytical techniques. For the texture analyser, the hardness and elasticity of crumb cakes were found to significantly increase and decrease, respectively throughout ageing. ...
Ren Dong Xue - - 2013
Two novel vanadium(iii) complexes: V(dipic)(Hbdc)(H(2)O)(2) () and [V(2)(dipic)(2)(H(2)btec)(H(2)O)(4)]·2H(2)O () (H(2)dipic = 2,6-pyridinedicarboxylic acid, H(2)bdc = 1,3-benzene-dicarboxylic acid, H(4)btec = 1,2,4,5-benzenetetracarboxylic acid) are synthesized by the reaction of V(2)(SO(4))(3), 2,6-pyridinedicarboxylic acid and 1,3-benzene-dicarboxylic acid (for ) or 1,2,4,5-benzenetetracarboxylic acid (for ) under hydrothermal condition at 120 °C for 3 days. They ...
Imafuku Shinichi - - 2013
Psoriasis is a chronic inflammatory skin disease associated with various complications such as arthritis, diabetes mellitus and hypertension. Hepatitis C is caused by chronic infection of hepatitis C virus (HCV), and eventually leads to liver cirrhosis and hepatocellular carcinoma. Although an association between psoriasis and HCV has been reported, there ...
Sharma Krishna Kant - - 2013
The variables influencing laccase production by white-rot fungus Ganoderma sp. rckk-02 were optimized employing response surface methodology. Malt extract (6.0% w/v), lignin (0.5% w/v) and pH (5.5) were found to be the most significant factors for enhanced laccase production by 7 fold (226.0 U/ml) as compared to unoptimized growth conditions (32.0 U/ml). ...
Soehnlein Oliver - - 2013
We used a novel approach of cytostatically induced leucocyte depletion and subsequent reconstitution with leucocytes deprived of classical (inflammatory/Gr1(hi) ) or non-classical (resident/Gr1(lo) ) monocytes to dissect their differential role in atheroprogression under high-fat diet (HFD). Apolipoprotein E-deficient (Apoe(-/-) ) mice lacking classical but not non-classical monocytes displayed reduced lesion ...
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