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Results 301 - 350 of 4302
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Brini Marisa - - 2013
The Ca(2+) ATPases of the plasma membrane (PMCA pumps) export Ca(2+) from all eukaryotic cells. In mammals they are the products of 4 separate genes. PMCA1 and 4 are distributed ubiquitously, PMCA 2 and 3 are restricted to some tissues, the most important being the nervous system. Alternative splicing at ...
Fusar-Poli P - - 2013
BACKGROUND: The past two decades have seen exponential clinical and research interest in help-seeking individuals presenting with potentially prodromal symptoms for psychosis. However, the epidemiological validity of this paradigm has been neglected, limiting future advancements in the field. Method We undertook a critical review of core epidemiological issues underlying the ...
Kanto Hiromi - - 2013
We investigated the optimum application for evaluating skin irritation response by using samples of irritants commonly used as additives in cosmetics and other common household products. We studied 47 volunteers (16 men and 31 women). We selected three types of surfactant, one moisturizer, one anti-infective agent and one oil solution. ...
Cambot Marie - - 2013
Lentiviral modification combined with ex vivo erythroid differentiation was used to stably inhibit RhAG expression, a critical component of the Rh(rhesus) membrane complex defective in the Rh(null) syndrome. The cultured red cells generated recapitulate the major alterations of native Rh(null) cells regarding antigen expression, membrane deformability and gas transport function, ...
Cano Paola Gauffin - - 2013
OBJECTIVES.: To evaluate the effects of administration of Bifidobacterium pseudocatenulatum CECT 7765 on metabolic and immune alterations in obese mice. DESIGN AND METHODS.: Adult male wild-type C57BL-6 mice were fed a standard diet or high-fat diet (HFD), supplemented or not with B. pseudocatenulatum CECT 7765 for seven weeks. The assessments ...
Tian Jingqi - - 2013
Cobalt phosphate (CoPi) nanoplates can be integrated with graphene oxide (GO) by photochemical deposition from an aqueous solution under visible-light illumination using GO as a photocatalyst. The use of the CoPi/GO composites as an oxygen-evolving catalyst with high efficiency is demonstrated. Integrating CoPi with GO leads to reduction of the ...
Mebane David S - - 2013
A statistical methodology was applied to the simultaneous calibration and validation of thermodynamic models for the uptake of CO(2) in mesoporous silica-supported amines. The methodology is Bayesian, and follows the procedure introduced by Kennedy and O'Hagan. One key aspect of the application presented is the use of quantum chemical calculations ...
Lelimousin Mickaël - - 2013
Carbon nanotubes (CNTs) can penetrate the membranes of cells, offering prospects for nanomedicine but problems for nanotoxicity. Molecular simulations are used to provide a systematic analysis of the interactions of single-walled and multi-walled CNTs of different radii with a model lipid bilayer membrane. The simulations allow characterisation of the mechanism ...
Bose Pinaki - - 2013
The 20(th) century saw great advances in anatomy-based (surgery and radiotherapy) and chemotherapy approaches for treating head and neck squamous cell carcinoma (HNSCC) and improving quality of life (QoL). However, despite these advances, the survival rate in HNSCC remains at ~50%. Front-line treatments often cause severe toxicity and debilitating long-term ...
Zhang Xing - - 2013
TiO(2) nanotube arrays loaded with carbon quantum dots were used as a photoanode for efficient hydrogen generation under visible light.
Sharma Krishna Kant - - 2013
The variables influencing laccase production by white-rot fungus Ganoderma sp. rckk-02 were optimized employing response surface methodology. Malt extract (6.0% w/v), lignin (0.5% w/v) and pH (5.5) were found to be the most significant factors for enhanced laccase production by 7 fold (226.0 U/ml) as compared to unoptimized growth conditions (32.0 U/ml). ...
Soehnlein Oliver - - 2013
We used a novel approach of cytostatically induced leucocyte depletion and subsequent reconstitution with leucocytes deprived of classical (inflammatory/Gr1(hi) ) or non-classical (resident/Gr1(lo) ) monocytes to dissect their differential role in atheroprogression under high-fat diet (HFD). Apolipoprotein E-deficient (Apoe(-/-) ) mice lacking classical but not non-classical monocytes displayed reduced lesion ...
Travado Luzia - - 2013
OBJECTIVE: This study addresses the meanings women with breast cancer attach to their illness within a cognitive-developmental framework. The aim of the present study was twofold: (i) to identify the content of women's meanings in five domains of breast cancer representation (identity, causes, consequences, timeline and controllability), and (ii) to ...
Sun Haiyan - - 2013
All carbon aerogels (up to 1000 cm(3) ) with ultralow density (down to 0.16 mg cm(-3) ) and temperature-invariant (-190-900 °C) super-elasticity are fabricated by facile assembling of commercial carbon nanotubes (CNTs) and chemically-converted giant graphene sheets, on the basis of the synergistic effect between elastic CNTs ribs and giant ...
Komiya Naruyoshi - - 2013
The synthesis, structure, and solid-state emission of vaulted trans-bis(salicylaldiminato)platinum(II) complexes are described. A series of polymethylene (1: n=8; 2: n=9; 3: n=10; 4: n=11; 5: n=12; 6: n=13) and polyoxyethylene (7: m=2; 8: m=3; 9: m=4) vaulted complexes (R=H (a), 3-MeO (b), 4-MeO (c), 5-MeO (d), 6-MeO (e), 4-CF(3) O ...
Yang Shubin - - 2013
We demonstrate that graphene-based porous silica sheets can serve as an efficient carrier support for PEI via a simple nanocasting technology. The resulting materials possess thin nature, high PEI loading content and high thermal-conductivity. Such features are favorable for the efficient diffusion and adsorption of CO(2) as well as the ...
Lichtenbelt Klaske D - - 2013
OBJECTIVE: This study aims to analyze differences in characteristics between women who opted for invasive testing after first-trimester combined testing and those who did not. METHOD: Follow-up was performed in 20 215 combined tests conducted between 2007 and 2011 in the central region of the Netherlands. Multivariate logistic regression analysis compared ...
Pan Yu-Shan - - 2013
A multi-drug resistant Escherichia coli C21 was isolated from a chicken in China. It was shown to be positive for the presence of the bla(TEM-1) , bla(CTX-M-55) and rmtB genes by PCR. This strain was examined by phylogenetic grouping, conjugation experiments, plasmid analysis, PCR-based replicon typing and multi-locus sequence typed ...
Karam Adib R - - 2013
AIM: to compare the diagnostic quality of tissue cores obtained using cranial and caudal angulation of the renal biopsy needle. Comparison was made in terms of the number of glomeruli and proportion of renal cortex with medulla on pathological analysis. METHODS: a total of forty desk top, renal biopsies were ...
Karino Yasuhito - - 2013
Transfer energetics from pure water to a urea-water mixture is examined for a set of amino acid analog solutes by using molecular dynamics simulation and free-energy calculation. The free energy of transfer from pure-water solvent to 8 M urea-water mixed solvent is calculated for each solute, and the urea-water mixture ...
Nakamae Toshio - - 2013
INTRODUCTION: The number of cases of osteoporotic vertebral compression fracture (OVCF) with intravertebral cleft (IVC) with delayed neurologic deficit (DND) is increasing as the population ages. However, the cause of DND is poorly understood, and no definitive treatment of the disease has been established. The purpose of this study was ...
Patenaude Andrea F - - 2013
OBJECTIVE: The objectives of this study are to determine (i) what daughters, ages 18-24 years, of BRCA1/2 mutation carriers understand about their 50% chance of carrying a BRCA1/2 mutation and about risk reduction or management options for mutation carriers, (ii) the extent and nature of daughters' cancer-related distress, and (iii) the ...
Erhardt Sascha A - - 2013
(Acetoxymethyl)silanes 2, 7 a-c, and 10 a-c with at least one alkoxy group, of the general formula (AcOCH(2) )Si(OR)(3-n) (CH(3) )(n) (R: Me, Et, iPr; n=0, 1, 2), were synthesized from the corresponding (chloromethyl)silanes 1, 6 a-c, and 9 a-c by treatment with potassium acetate under phase-transfer-catalysis conditions. These compounds were found to provide ...
Guichelaar Mmj - - 2013
OBJECTIVE: Allelic variation (rs738409C→G) in adiponutrin (PNPLA3) has been associated with hepatic steatosis, and liver fibrosis. The physiologic impact of the PNPLA3 G allele may be exacerbated in patients with severe obesity. In this study, we investigated the interactions of PNPLA3 rs738409 with a broad panel of metabolic and histologic ...
Tiong Erica A - - 2013
Distant relative: The configuration of the quaternary stereocenter in puraquinonic acid is defined by groups far removed from the point of asymmetry. The use of a bicyclic thioglycolate lactam to set the quaternary stereocenter at an early stage cuts the length of the synthesis of the natural product by nearly ...
Olschewski Martin - - 2013
Back and forth: Femtosecond two-dimensional infrared exchange spectroscopy was used to study the dynamics of the reversal of an intramolecular hydrogen bond. The H-bond reversal resembles a flip-flop motion that is facilitated by two concerted disrotatory torsional isomerizations and that occurs on a time scale of about 2 ps.
van Gastel W A - - 2013
BACKGROUND: Cannabis use is associated with increased risk for psychotic-like experiences (PLEs) and psychotic disorders. It remains unclear whether this relationship is causal or due to confounding. Method A total of 1929 young adults aged 18-30 years participated in a nationwide internet-based survey in The Netherlands and gave information on ...
Yachida S - - 2013
Efficient metastasis is believed as the result of multiple genetic, epigenetic and/or post-translational events in the lifetime of a carcinoma. At the genetic level, these events may be categorized into those that occur during carcinogenesis, and those that occur during subclonal evolution. This review summarizes current knowledge of the genetics ...
Liu Jing-Min - - 2013
The simplicity of the green-synthesized routine and the availability of surface modification of diverse bioactive molecules make noble metal nanostructures highly suitable as multifunctional biomaterials for biological and biomedical application. Here we report the preparation of trypsin stabilized gold nanoclusters (try-AuNCs) with near-infrared fluorescence for biosensing heparin based on surface ...
Gomes Caio Perez - - 2013
PROBLEM: Gestational diabetes mellitus (GDM) is an inflammatory condition that involves unbalanced cytokine production. We carried out a systematic review on the relationship between GDM and maternal circulating levels of cytokines in the 2nd/3rd trimesters. METHOD OF STUDY: Three electronic databases (MEDLINE, EMBASE and LILACS), were searched. Duplicate study selection, ...
Pompa Marianna - - 2013
Gluten protein composition and expression level influence dough properties and are cultivar and environment dependent. In order to broaden the knowledge of durum wheat gluten proteome, three cultivars were compared in two different growing seasons by a proteomic approach. Cultivar specific and differentially expressed spots in the two years were ...
Lee Young-Chul - - 2013
In recent decades, harmful algal blooms (HABs) - commonly known as red tides - have increasingly impacted human health, caused significant economic losses to fisheries and damaged coastal environments and ecosystems. Here, we demonstrate a method to control and suppress HABs through selective algal lysis. The approach harnesses the algicidal ...
Maskrey Benjamin H - - 2013
The beneficial health properties of dietary omega-3 polyunsaturated fatty acids, particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have long been known and their metabolic dysfunction has been linked to a range of diseases including various inflammatory disorders, cardiovascular diseases, and cancer. However, the molecular mechanisms underlying their health benefits ...
Liu Tao - - 2013
We report a facile one-pot sonochemical approach to preparing highly water-soluble Ag nanoclusters (NCs) using bovine serum albumin as a stabilizing agent and reducing agent in aqueous solution. Intensive electrogenerated chemiluminescence (ECL) was observed from the as-prepared Ag (NCs) and successfully applied for the ECL detection of dopamine with high ...
Yin Lichen - - 2013
Supramolecular self-assembled nanocomplexes (SSANs) capable of mannose receptor-mediated endocytosis and permeable to cellular and endosomal membranes are developed via the assembly of multiple rationally designed, function-specific materials. As a unique non-viral gene delivery vector, SSANs outperform commercial transfection reagents, including LPF2000, PEI, and jetPEI, by up to 2 orders of ...
Yavas Hakan - - 2013
Background: Renal tubulointerstitial injury plays an important role in disease progression of IgAN. Neutrophil gelatinase-associated lipocalin (NGAL) is a stress protein released by tubular cells. NGAL is a promising biomarker of acute kidney injury. There is a growing literature suggesting that NGAL is also a marker of chronic kidney disease ...
Chandra Subani - - 2013
PURPOSE: Sympathetic activation induced by sleep-disordered breathing may contribute to cardiovascular morbidity. However, the apnea-hypopnea index (AHI) excludes respiratory effort-related arousals (RERAs) associated with inspiratory flow limitation without oxygen desaturation. We sought to determine whether RERAs are associated with sympathetic activation. METHODS: Twenty-five adults (12 males, 13 females) with AHI < 10/h ...
Wang Nengwen - - 2013
Geometrical diffuse reflection is a common optical phenomenon that occurs when a reflecting surface has roughness of order of hundreds of micrometres. Light rays thus reflect uniformly in all directions with each ray obeying Snell's law. Of interest is knowing what happens when light reflects off surfaces with roughness of ...
Zhang Lei - - 2013
Precious iron: A new PNN iron complex has been developed for use in an iron-catalyzed alkene hydroboration reaction under mild conditions. The environmentally friendly and earth-abundant iron catalyst system is superior to precious-metal systems in terms of efficiency and selectivity for α-olefin hydroborations with pinacolborane.
Zhu Cun - - 2013
This article describes an aqueous method for the synthesis of Pd seeds with a single-crystal structure and a uniform diameter of 3 nm and their use for the growth of Pd nanocrystals with a variety of shapes. We have also investigated the effects of a number of parameters, including the temperature, ...
Yu Bingran - - 2013
A π-conjugated AB(2) monomer 1 with a dibenzo[24]crown-8 (DB24C8) ring and two secondary amine centres has been synthesised. Treatment of a solution of 1 in dichloromethane with trifluoroacetic acid (TFA) leads to protonation of the amine groups, and then the DB24C8 rings are threaded by the dialkylammonium ion centres of ...
Asiimwe Benon B - - 2013
ABSTRACT: BACKGROUND: Smear microscopy, a mainstay of tuberculosis (TB) diagnosis in developing countries, cannot differentiate M. tuberculosis complex from NTM infection, while pulmonary TB shares clinical signs with NTM disease, causing clinical and diagnostic dilemmas. This study used molecular assays to identify species and assess genotypic diversity of non-tuberculous mycobacteria ...
Dragano Nathalia R V - - 2013
The peel of the native Brazilian fruit jaboticaba is rich in anthocyanins, which are known for their anti-obesity effects in animal models. The aim of the present study was to evaluate the effects of freeze-dried jaboticaba peel powder (FDJPP) on a number of metabolic parameters in a model of diet-induced ...
Li W - - 2013
Cervical cancer is the most common genital malignancy and the high-risk human papillomaviruses (HPV type 16, 18 and 31, and so on) are major agents for its cause. A key switch for the onset of cervical cancers by HPVs is the cellular degradation of the tumor-suppressor p53 that is mediated ...
Chaikittisilp Watcharop - - 2013
Make intergrowth, not war! Hierarchically organized MFI zeolites possessing micro-, meso-, and macroporosity in one structure were made by sequential intergrowth using a simple organic structure-directing agent (OSDA) without meso- or macroporogens. The use of an OSDA that imperfectly fit the zeolite framework generated very thin zeolite plates with 90° ...
Polsen Erik S - - 2013
The widespread potential application of vertically aligned carbon nanotube (CNT) forests have stimulated recent work on large-area chemical vapor deposition growth methods, but improved control of the catalyst particles is needed to overcome limitations to the monodispersity and packing density of the CNTs. In particular, traditional thin-film deposition methods are ...
Apostolakis Dimitrios - - 2013
OBJECTIVES: The superior alveolar canal with its contents is frequently reported as an anatomical point of consideration during lateral sinus floor elevation due to the danger of bleeding and of the subsequent impairment of vision of the surgical field. Malnutrition of the graft may also ensue. This radiographical study uses ...
Lee Jin-Gu - - 2013
Upon emerging from the ribosome exiting tunnel, polypeptide folding occurs immediately with the assistance of both ribosome-associated and free chaperones. While many chaperones known to date are dedicated folding catalysts, recent studies have revealed a novel chaperoning system that functions at the interface of protein biogenesis and quality control by ...
Sattler Elke - - 2013
Sentinel lymph node biopsy (SLNB) is commonly recommended for patients with primary Merkel cell carcinoma (MCC). However, it is critically discussed whether survival rates improve by SLNB in MCC patients in general or in subgroups of higher risk (e.g. with primary tumor size >1 cm). The present study correlates clinical data, ...
Reid Jennifer N S - - 2013
PROBLEM: Medical problems of most importance to reproductive health of women differ to some extent between the developed world and resource-disadvantaged countries. Nevertheless, many share a common link in microbial involvement. METHOD OF STUDY: A review of the peer-reviewed literature on microbiota, probiotics, and reproductive health. RESULTS: Indigenous and probiotic ...
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