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Marzaro Giovanni G Dipartimento di Scienze del Farmaco, Università degli Studi di Padova, Via Marzolo 5, 35131 Padova, - - 2013
Some new psoralen derivatives were synthesized and evaluated as inhibitors of NF-κB/DNA interaction, with the aim to investigate the structural determinants required to inhibit this interaction. Starting from molecular docking studies, several possible protein binding sites were proposed and several three-dimensional quantitative structure-activity relationship (3D-QSAR) models were built using the ...
Gahlmann Andreas A Department of Chemistry, Stanford University, Stanford, California 94305, United - - 2013
We demonstrate quantitative multicolor three-dimensional (3D) subdiffraction imaging of the structural arrangement of fluorescent protein fusions in living Caulobacter crescentus bacteria. Given single-molecule localization precisions of 20-40 nm, a flexible locally weighted image registration algorithm is critical to accurately combine the super-resolution data with <10 nm error. Surface-relief dielectric phase ...
Abuznait Alaa H AH Department of Basic Pharmaceutical Science, College of Pharmacy, University of Louisiana at Monroe, 1800 Bienville Drive, Monroe, Louisiana 7120, United - - 2013
Oleocanthal, a phenolic component of extra-virgin olive oil, has been recently linked to reduced risk of Alzheimer's disease (AD), a neurodegenerative disease that is characterized by accumulation of β-amyloid (Aβ) and tau proteins in the brain. However, the mechanism by which oleocanthal exerts its neuroprotective effect is still incompletely understood. ...
Panthier Christophe - - 2013
The authors describe a case of combined full-thickness retinal and pigment epithelium macular hole that spontaneously developed in the right eye of an 86-year-old woman with age-related macular degeneration (AMD). One year prior, the patient had been diagnosed with drusenoid pigment epithelium detachment (PED) in the right eye and geographic ...
Henry Christopher R - - 2013
The authors report the fluorescein angiography findings in a 3-month-old patient with phacomatosis cesioflammea, which revealed venous-venous anastomoses in addition to previously undescribed features of peripheral retinal vascular nonperfusion. The authors encourage physicians to consider phacomatosis pigmentovascularis in the differential diagnosis of patients presenting with facial port-wine stain and to ...
Harris Michael R MR Department of Chemistry, 4114 Natural Sciences 1, University of California, Irvine, California 92697, United - - 2013
Stereospecific coupling of benzylic carbamates and pivalates with aryl- and heteroarylboronic esters has been developed. The reaction proceeds with selective inversion or retention at the electrophilic carbon, depending on the nature of the ligand. Tricyclohexylphosphine ligand provides the product with retention, while an N-heterocyclic carbene ligand provides the product with ...
Costa Cristina - - 2013
The role of human cytomegalovirus (HCMV) in lung transplantation (LT) and drawbacks related to viral quantification in bronchoalveolar lavage (BAL) underline the potential usefulness of investigating other specimens. Thirty-three LT recipients were prospectively studied by HCMV quantitative real time PCR on matched transbronchial biopsy (TBB), BAL, and whole blood specimens. ...
Takigawa Masateru - - 2013
BACKGROUND: Although several predictors of an electrical storm (ES) are indicated in patients with idiopathic dilated cardiomyopathy (IDCM), whether the severity of the myocardial tissue damage (SMTD) evaluated by myocardial perfusion SPECT (MPS) has an association with an ES remains unclear. The purpose of this study was to elucidate the ...
Zhang Xiangning - - 2013
Up to now, seven viruses that infect humans have been identified as oncogenic and are closely associated with different human cancers. Most of them encode oncogenes whose products play important roles in the development of cancers in the context of environmental and genetic factors; others may act via indirect mechanisms. ...
Lan Daoliang - - 2013
The local intestinal mucosa, the largest mucosal immune system in animals, plays an important role in resistance against intestinal pathogen infection. However, the molecular antiviral mechanisms of the intestinal mucosa remain poorly understood. In this study, we screened and identified differentially expressed transcripts in (PSV) porcine intestinal epithelial cells (IPEC-J2) ...
Sikorski Alyssa - - 2013
During routine monitoring of yellow-crowned parakeets in the Poulter Valley of the South Island of New Zealand, a dead parakeet chick was discovered in a nest. Known parrot-infecting viruses, such as beak and feather disease virus (BFDV), avian polyomavirus (APV), and parrot hepatitis B virus (PHBV), were not detected in ...
Dinzeo Thomas J - - 2013
The authors describe the development and preliminary evaluation of the Lifestyle and Habits Questionnaire-brief version (LHQ-B). Three hundred seventy-seven undergraduate students (ages 18-25) participated. Responses were collected through either a web-based or face-to-face survey. Data reductive procedures were used with a preexisting lifestyle inventory to create an abbreviated measure. The ...
Allen Michael J - - 2013
While the relationship between weather and human health has been studied from various perspectives, this study examines an alternative method of analysis by examining weather conditions on specific high-mortality days during the winter season. These high-mortality days, by definition, represent days with dramatic increases in mortality and the days with ...
Homard Catherine M - - 2013
The purpose of this ex post facto correlational study was to compare exit examination scores and NCLEX-RN® pass rates of baccalaureate nursing students who differed in level of participation in a standardized test package. Three cohort groups emerged as a standardized test package was introduced: (a) students who did not ...
Gugleta K - - 2013
PURPOSE: To analyze neurovascular coupling in the retina of untreated primary open-angle glaucoma (POAG) and ocular hypertension (OHT) patients. PATIENTS AND METHODS: Maximal vessel dilation in response to flicker light was analyzed with Retinal Vessel Analyzer (RVA) in temporal superior/inferior arterioles and veins in 51 POAG patients, 46 OHT and ...
He Xiaozhen - - 2013
The success of gene transfer has been demonstrated in many of vertebrate species, whereas the efficiency of producing transgenic animals remains pretty low due to the random integration of foreign genes into a recipient genome. The Sleeping Beauty (SB) transposon is able to improve the efficiency of gene transfer in ...
Tay Louis - - 2013
In light of recent interest in societal subjective well-being, policies that seek to improve the economy and labor markets need to address the question of whether economic factors matter for worker well-being, specifically job satisfaction. In a worldwide representative poll of 136 nations, economic factors are associated with job satisfaction ...
Yeo Samuel Chao Ming - - 2013
SCOPE: Pterostilbene (trans-3,5-dimethoxy-4'-hydroxystilbene, PTS) possesses various health-promoting effects. This study aimed to investigate the impacts of aqueous solubility, fasting, dose escalation, and dosing route on its bioavailability in Sprague-Dawley rats. METHODS AND RESULTS: Upon intravenous administration (2.5 mg/kg), PTS had rapid clearance (Cl = 68.2 ± 9.8 mL/min/kg) and moderate ...
Mishra Arabinda - - 2013
The overall goal of this work is to demonstrate how resting state functional magnetic resonance imaging (fMRI) signals may be used to objectively parcellate functionally heterogeneous subregions of the human amygdala into structures characterized by similar patterns of functional connectivity. We hypothesize that similarity of functional connectivity of subregions with ...
Lin Huandong - - 2013
OBJECTIVE: To evaluate the new DXA VAT method on an Asian Chinese population by comparing to a reference method, computed tomography (CT). DESIGN AND METHODS: In total, 145 adult men and women volunteers, representing a wide range of ages (19 to 83 years) and BMI values (18.5 to 39.3 kg/m(2) ...
Na Kyoung-Sae - - 2013
OBJECTIVE: This study assessed whether the subjective experience of patients with schizophrenia improved after switching from an oral antipsychotic to flexibly-dosed paliperidone extended-release. METHODS: We conducted a 24-week, multicenter, non-comparative, open-label trial. A total of 387 patients with schizophrenia participated the study. The primary study outcome was the change in ...
Gross Avner - - 2013
The input of phosphorus (P) through atmospheric deposition can be a major source of P to fresh water bodies, and may strongly affect their biogeochemistry. In Lake Kinneret (LK), northern Israel, dust deposition provides a significant fraction of the bio-available P input. Here we demonstrate that the oxygen isotopic composition ...
Agarwal Ajay - - 2013
Pseudo-progression (PsP) refers to the paradoxical increase of contrast enhancement within 12 weeks of chemo-radiation therapy in gliomas attributable to treatment effects rather than early tumor progression (ETP). This study was performed to evaluate the utility of morphologic imaging features, diffusion tensor imaging (DTI) and radiation dosimetric analysis of magnetic resonance ...
Righetti Pier Giorgio - - 2013
This review, compiled for celebrating the decennial of the series of issues of Electrophoresis on bioanalysis, does not cover much heri (yesterday in Latin), since this was extensively described by my previous review Electrophoresis 2004, 25, 2111-2127, nor, for that matter cras (tomorrow, in Latin) since making predictions on future ...
Vyslouzilova Lenka - - 2013
In this study, we determined serum levels of metallothioneins (MTs) and zinc in children with solid tumours (neuroblastoma, Hodgkin lymphoma, medulloblastoma, osteosarcoma, Ewing sarcoma and nephroblastoma) by differential pulse voltammetry Brdicka reaction and enzyme-linked immunosorbent assay. Zn(II) level in patients sera was 40% compared to controls, contrariwise, MT level was ...
Tomić Vajdana - - 2013
Abstract Objective. To determine thresholds of maternal glycemia at which specific adverse pregnancy outcomes occur in high-risk population. Methods. A total of 1,002 pregnant women with risk factors for gestational diabetes mellitus (GDM) underwent an originally modified glucose tolerance test (OGTT) with 75g of glucose. Information on OGTT results and ...
Pender-Cudlip Marilla C - - 2013
Omega-6 (n-6) arachidonic acid (AA) and its pro-inflammatory metabolites, including prostaglandin E2 (PGE(2) ), are known to promote tumorigenesis. Delta-6 desaturase (D6D) is the rate-limiting enzyme for converting n-6 linoleic acid (LA) to AA. Our objective was to determine if AA synthesis, specifically D6D activity, and PGE(2) levels are increased ...
Donmez Gizem - - 2013
Sirtuins are NAD-dependent protein deacetylases known to have protective effects against age-related diseases such as cancer, diabetes, cardiovascular and neurodegenerative diseases. In mammals, there are seven sirtuins (SIRT1-7), which display diversity in subcellular localization and function. While SIRT1 has been extensively investigated due to its initial connection with lifespan extension ...
You Bo - - 2013
A MnO(2) -CNT-graphene oxide (MCGO) nanocomposite is fabricated using graphene oxide (GO) as a surfactant to directly disperse pristine carbon nanotubes (CNTs) for the subsequent deposition of MnO(2) nanorods. The resulting MCGO nanocomposite is used as a supercapacitor electrode that shows ideal capacitive behavior (i.e., rectangular-shaped cyclic voltammograms), large specific ...
Hanson Summer E - - 2013
Wound healing remains a major challenge in modern medicine. Bone marrow- (BM) and adipose tissue- (AT) derived mesenchymal stromal/stem cells (MSCs) are of great interest for tissue reconstruction due to their unique immunological properties and regenerative potential. The purpose of this study was to characterize BM and AT-MSCs and evaluate ...
Siervo Mario - - 2013
OBJECTIVE: The nutrition transition model provides an integrated approach to analyse global changes in food consumption and lifestyle patterns. Whether variability in food availability for consumption, lifestyle and sociodemographic factors is associated with the worldwide prevalence distribution of overweight, obesity and hypertension is unclear. DESIGN: Ecological analysis. SETTING: Country-specific prevalence ...
Hu Han - - 2013
Chemically converted graphene aerogels with ultralight density and high compressibility are prepared by diamine-mediated functionalization and assembly, followed by microwave irradiation. The resulting graphene aerogels with density as low as 3 mg cm(-3) show excellent resilience and can completely recover after more than 90% compression. The ultralight graphene aerogels possessing ...
Spina Rosella - - 2013
Design for diversity: A new catalytic system based on PEG-3400 and a metal salt (Pt or Au) was designed to efficiently perform a cycloisomerization reaction under microwave irradiation, which gave diverse heterocycles in good to excellent yields, after a precipitation/filtration procedure.
Li Yong-Jie - - 2013
A novel strategy is developed for the fabrication of graphene-CdS (G-CdS) nanocomposites by in situ growth of CdS nanoparticles onto simultaneously reduced graphite oxide, which is noncovalently functionalized by sodium 1-pyrene sulfonate through strong π-π stacking interactions. Subsequently, cobalt 2,9,16,23-tetraaminophthalocyanine (CoTAPc) is self-assembled on the G-CdS nanocomposites through electrostatic interactions ...
Mazur-Bialy Agnieszka Irena - - 2013
Riboflavin, or vitamin B2, as a precursor of the coenzymes FAD and FMN, has an indirect influence on many metabolic processes and determines the proper functioning of several systems, including the immune system. In the human population, plasma riboflavin concentration varies from 3·1 nm (in a moderate deficiency, e.g. in pregnant ...
Murphy Debra A - - 2013
Abstract In this study, late adolescents/early adults whose mothers were living with HIV (MLH) were interviewed in order to explore their perceptions of what it had been like for them to grow up under the shadow of their mothers' illness. Adolescents were asked to describe what the difficult aspects of ...
Hill J Grant - - 2013
Benchmark quality geometries and interaction energies for the prereactive halogen-bonded complexes of dihalogens and ammonia, including hypothetical astatine containing dihalogens, have been produced via explicitly correlated coupled cluster methods. The application of local electron correlation partitioning reveals dispersion, electrostatics and ionic substitutions all contribute significantly to the interaction energy, with ...
Li Yongqing - - 2013
Oct4 is the gatekeeper of stem cell pluripotency, but recent evidences also support Oct4 as a key regulator of germ layer formation and lineage commitment. How Oct4 contributes to lineage commitment is not well understood. We identified a Tcf/Lef-Oct4 composite site in the promoter of the cardiac mesoderm gene Mesp1, ...
Sowndhararajan K - - 2013
AIMS: The present study was aimed to evaluate the integration of Ochrobactrum anthropi BMO-111 and chemical fungicides (copper oxychloride and hexaconazole) against blister blight disease of tea. METHODS AND RESULTS: Application of the liquid culture of O. anthropi BMO-111 (36-h-old culture broth) was found to be effective in combined sprays with ...
Feng Xingmei - - 2013
ABSTRACT: BACKGROUND: Hydrogen sulfide (H2S), an endogenous gaseotransmitter/modulator, is becoming appreciated that it may be involved in a wide variety of processes including inflammation and nociception. However, the role and mechanism for H2S in nociceptive processing in trigeminal ganglion (TG) neuron remains unknown. The aim of this study is to ...
Villa Ana Lúcia - - 2013
ABSTRACT: BACKGROUND: Hair is composed mainly of keratin protein and a small amount of lipid. Protein hydrolysates, in particular those with low molecular weight distribution have been known to protect hair against chemical and environmental damage. Many types of protein hydrolysates from plants and animals have been used in hair ...
Ashraf Raja Shahid - - 2013
A series of low bandgap indacenodithiophene polymers is purified by recycling SEC in order to isolate narrow polydispersity fractions. This additional purification step is found to have a significant beneficial influence on the solar cell performance and the reasons for this performance increase are investigated.
Qu Shuanglin - - 2013
Polyols pathway probed: Density functional theory computations reveal that the methyltrioxorhenium-catalyzed deoxydehydration of polyols follows the pathway C, which is energetically more favorably than the previously proposed pathways A and B. In addition to serving as solvent/reductant, the alcohol also acts as a shuttle to greatly facilitate various hydrogen-transfer steps.
Pratsinis Anna - - 2013
Silver nanoparticles (nanosilver) are broadly used today in textiles, food packaging, household devices and bioapplications, prompting a better understanding of their toxicity and biological interactions. In particular, the cytotoxicity of nanosilver with respect to mammalian cells remains unclear, because such investigations can be biased by the nanosilver coatings and the ...
Gandjour Afschin - - 2013
Health interventions have two major downstream cost effects, savings from reducing morbidity and expenditures from living longer. Anecdotal evidence suggests that many economic evaluations, particularly those that are trial-based, do not include health care costs from living longer. The purpose of this study was therefore to determine the bias from ...
Mai Thanh Duc - - 2013
A detailed study on the effect of the buffer concentration and the magnitude of the superimposed hydrodynamic flow on separation performance in capillary zone electrophoresis with contactless conductivity detection was carried out with capillaries of 10, 25 and 50 μm internal diameter. It was confirmed that capillaries of narrow internal ...
Scorgie Fiona - - 2013
Sex workers in east and southern Africa are exposed to multiple occupational health and safety risks. Detailed understanding of barriers to accessing care would optimise design of improved services for this population. In this study, trained sex workers conducted 55 in-depth interviews and 12 focus group discussions with 106 female, ...
Shimamura Junichi - - 2013
ABSTRACT: A 78-year-old man, who had previously undergone coronary artery bypass graft surgery, was admitted to our department for treatment of a distal aortic arch aneurysm. A total aortic arch replacement with a patent left internal thoracic artery (LITA) graft was successfully performed without cardiac ischemic or neurological complications. Use ...
Zhou Han - - 2013
Fast flexible electronics operating at radio frequencies (>1 GHz) are more attractive than traditional flexible electronics because of their versatile capabilities, dramatic power savings when operating at reduced speed and broader spectrum of applications. Transferrable single-crystalline Si nanomembranes (SiNMs) are preferred to other materials for flexible electronics owing to their unique ...
Fischer Dennis - - 2013
1-Hydroxy-5-aminotetrazole (1), which is a long-desired starting material for the synthesis of hundreds of new energetic materials, was synthesized for the first time by the reaction of aqueous hydroxylamine with cyanogen azide. The use of this unique precursor was demonstrated by the preparation of several energetic compounds with equal or ...
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