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Yacoub Michael - - 2013
The purpose of this study was to determine whether surgical approach and patient demographics are important factors that influence lymph node retrieval. This was a retrospective review of patients receiving surgical treatment for colorectal cancer at a single institution. Two hundred three patients underwent resection for colorectal cancer. The total ...
Dowell Deborah - - 2013
The development of resistance to multiple antimicrobial agents has limited treatment options for gonorrhoea. The potential emergence of cephalosporin resistance in Neisseria gonorrhoeae and cephalosporin allergy in some patients make it necessary to evaluate the effectiveness of other available antimicrobial agents. Gentamicin is widely available in the USA and is ...
Kravchenko Julia - - 2013
Global climate change is projected to increase the frequency and duration of periods of extremely high temperatures. Both the general populace and public health authorities often underestimate the impact of high temperatures on human health. To highlight the vulnerable populations and illustrate approaches to minimization of health impacts of extreme ...
Kelly Paul - - 2013
Technologic advances mean automated, wearable cameras are now feasible for investigating health behaviors in a public health context. This paper attempts to identify and discuss the ethical implications of such research, in relation to existing guidelines for ethical research in traditional visual methodologies. Research using automated, wearable cameras can be ...
Sever Peter - - 2013
Hypotension and syncopal attacks have been reported in association with drugs which block the renin-angiotensin-aldosterone system (RAAS). It has been proposed that the underlying mechanism is due to sensitisation of the Bezold-Jarisch reflex leading to withdrawal of sympathetic tone, profound and prolonged bradycardia, and hypotension. Sensitisation of this reflex occurs ...
Allen Thomas W - - 2013
Acute cholecystitis (AC) and lower-gastrointestinal (GI) bleeding are 2 emergencies commonly encountered in nuclear medicine. Evidence of AC on hepatobiliary scintigraphy (HBS) allows for confident diagnosis and provides support for definitive surgical treatment. Proper patient preparation is essential for HBS including fasting and the use of pharmacologic adjuncts is sometimes ...
Brooks Audrey J AJ Arizona Center for Integrative Medicine, University of Arizona, Tucson, AZ 85724, USA. - - 2013
HIV infection disproportionately impacts minorities; yet research on racial/ethnic differences in the prevalence and correlates of HIV risk behaviors is limited. This study examined racial/ethnic differences in the rates of HIV risk behaviors and whether the relationship between HIV risk factors and HIV risk behaviors varies by race/ethnicity in clients ...
Adkison Sarah E SE Department of Health Behavior, Roswell Park Cancer Institute, Buffalo, NY 14263, - - 2013
Electronic nicotine delivery systems (ENDS) initially emerged in 2003 and have since become widely available globally, particularly over the Internet. Data on ENDS usage patterns are limited. The current paper examines patterns of ENDS awareness, use, and product-associated beliefs among current and former smokers in four countries. Data come from ...
Bratke K - - 2013
Plasmacytoid dendritic cells (pDCs) infiltrate sites of acute Th2-dominant inflammation, but their role in allergic asthma remains unclear. To characterize circulating pDCs from patients with allergic asthma outside their respective allergen season. Adhesion molecules, co-stimulatory molecules, immunoglobulin receptors and chemokine receptors were quantified on blood pDCs from 20 patients with ...
Tang Min Moon - - 2013
Background  Psoriasis is an immune-mediated, chronic, inflammatory skin disease which affects approximately 2% of the world's population. It has a major impact on the patient's quality of life (QoL), influencing career, social activities, family relationships, and all other aspects of life. Many studies have described the various ways in which ...
Taggarshe Deepa - - 2013
Colorectal cancer (CRC) is increasing in young patients. We aimed to assess the trends of CRC and its corresponding clinical presentation in the young. Cancer registry patients were divided into 3 groups according to age:<50, 50-75, and >75 years. Charts were reviewed for average-risk patients <50 years of age to assess ...
Rindal D Brad DB HealthPartners Institute for Education and Research, Minneapolis, MN 55425, USA. - - 2013
Decreases in smoking prevalence from recent decades have slowed, and national goals to reduce tobacco use remain unmet. Healthcare providers, including those in physician and dental teams, have access to evidence-based guidelines to help patients quit smoking. Translation of those guidelines into practice, however, remains low. Approaches that involve screening ...
Few Roger - - 2013
Any analysis of how changing environmental hazards impact on public health is fundamentally constrained unless it recognizes the centrality of the social and behavioral dimensions of risk. This paper reports on a research project conducted among low-income peri-urban households in the Mekong Delta of Vietnam. The research was based on ...
Eghtesady Pirooz - - 2013
Several efforts are under way to conduct quality-improvement initiatives in pediatric cardiology and cardiac surgery. Our goal was to develop an objective prioritization scheme for such initiatives based on encounter frequency and relative contribution of quality measures of morbidity (and associated variances), particularly in the setting of low mortality. We ...
Turner Martin R MR Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, - - 2013
Two decades after the discovery that 20% of familial amyotrophic lateral sclerosis (ALS) cases were linked to mutations in the superoxide dismutase-1 (SOD1) gene, a substantial proportion of the remainder of cases of familial ALS have now been traced to an expansion of the intronic hexanucleotide repeat sequence in C9orf72. ...
Love Charito - - 2013
Although infection may be suggested by signs and symptoms such as fever, pain, general malaise, and abnormal laboratory results, imaging tests often are used to confirm its presence. Morphologic imaging tests identify structural alterations of tissues or organs that result from a combination of microbial invasion and the inflammatory response ...
Lawson Katie M KM Department of Human Development and Family Studies, Pennsylvania State University, State College, PA, USA. - - 2013
Exposure to traumatic events is common among individuals with substance use disorders. Little is known, however, about the trauma histories among individuals with various types of addiction. The present study compared the trauma histories (general, sexual, physical and emotional) of non-treatment seeking outpatients dependent on prescription opioids (n = 41), ...
Hu Po-Ting - - 2013
OBJECTIVE: The aim of this study was to determine the effect of using a cane on movement time, joint moment, weight symmetry, and muscle activation patterns during sit-to-stand (STS) transfer in healthy subjects and subjects who have had a stroke. DESIGN: Nine subjects with hemiparesis (mean [SD] age, 61.11 [12.83] ...
Mangus Richard S - - 2013
Intestinal failure (IF) occurs when a person's functional intestinal mass is insufficient. Patients with IF are placed on parenteral nutrition (PN) while efforts are made to restore intestinal function through surgical or medical intervention. Patients who fail standard IF therapies may be candidates for intestinal transplantation (IT). Clinical outcomes for ...
Mayle Brenda A - - 2013
The grey squirrel, Sciurus carolinensis Gmelin, was introduced into sites in England, Wales, Scotland and Ireland from the United States and Canada between 1876 and 1929. Soon after its introduction there were reports of damage to trees by seasonal bark stripping activity. Surveys in state and private forests since 1954 ...
Kerr Jacqueline - - 2013
Studies have shown relationships between important health outcomes and sedentary behavior, independent of physical activity. There are known errors in tools employed to assess sedentary behavior. Studies of accelerometers have been limited to laboratory environments. To assess a broad range of sedentary behaviors in free-living adults using accelerometers and a ...
Núñez-Córdoba Jorge M - - 2013
Obesity has become a major health and economic problem with increasing prevalence. Unfortunately, no country can act as public health exemplar for reduction of obesity. The finding of associations between sedentary behaviors and obesity, independent of the level of physical activity, may offer new insights to prevent this burdensome problem. ...
Man Stephen - - 2013
The early 1990s saw the first clinical testing of several therapeutic cancer vaccines. There was great optimism that these vaccines could be used as an alternative therapy for patients who had failed to respond to conventional cancer therapies. This article provides a personal perspective on the cancer vaccine field after ...
Harb H - - 2013
Oral supplementation with probiotic bacteria can protect against the development of allergic and inflammatory diseases. The aim of this study was to investigate potential immunomodulatory and allergy-protective effects of processed Lactobacillus rhamnosus GG (LGG)-derived supernatants early in life in neonatal mice. In vitro, RAW264.7 mouse macrophages were stimulated with viable ...
Flint Lisa - - 2013
This feature looks at changing the format of a well-established information skills session for first-year biochemistry students at UCL, to improve its design, delivery and the overall learning experience for the students. After reviewing current literature, active learning methods were explored and an idea of a research-based quiz based on ...
Silva Ana R - - 2013
One of the core applications of Microsoft's SenseCam is memory rehabilitation. Research has shown that it is an effective memory aid that can cue episodic memories. However, the extent to which SenseCam might improve aspects of memory beyond merely re-presenting forgotten events and locations has not been assessed. In line ...
Centner Chad M CM Neurology Research Group, Department of Medicine, Groote Schuur Hospital, University of Cape Town, Cape Town, South - - 2013
Peripheral nerve disorders are associated with all stages of HIV infection. Distal sensory polyneuropathy is characterised by often-disabling pain that is difficult to treat. It is prevalent in both high-income and low-income settings. In low-income settings, use of potentially neurotoxic antiretrovirals, which are inexpensive and widely available, contributes substantially to ...
Issa Maria C A - - 2013
Epidermal permeability alterations induced by ablative fractional resurfacing and low-frequency ultrasound technology may offer drug delivery for the treatment of hypertrophic scars through transepidermal drug delivery (TED). This technology can improve treatment efficacy and minimize side effects. To evaluate clinical response and side effects of TED technology in hypertrophic scars ...
Ghatak Abhijit - - 2013
Acute chest pain suggestive of ischemic cardiac origin, with a normal or nondiagnostic electrocardiogram and negative initial cardiac markers for myocardial necrosis represent a significant diagnostic dilemma for clinicians. Multiple imaging modalities play a pivotal role in early diagnosis and safe discharge of these patients. In this review, we compare ...
Brown Barbara B BB Department of Family and Consumer Studies, University of Utah, Salt Lake City, UT 84112-0080, USA. - - 2013
Neighborhood designs often relate to physical activity and to BMI. Does neighborhood walkability/bikeability relate to BMI and obesity risk and does moderate-to-vigorous physical activity (MVPA) account for some of the relationship? Census 2000 provided walkability/bikeability measures-block group proportions of workers who walk or bike to work, housing age, and population ...
Hancox R J - - 2013
Studies indicate an increased risk of allergies among children born by caesarean section, possibly because immune development is altered by avoiding exposure to maternal vaginal flora. It is unknown if other obstetric interventions are associated with allergies. To assess associations between delivery with forceps assistance and development of atopy and ...
Grossniklaus Ueli U Institute of Plant Biology and Zürich-Basel Plant Science Center, University of Zürich, Zollikerstrasse 107, CH-8008 Zürich, Switzerland. - - 2013
Much attention has been given to the idea of transgenerational epigenetic inheritance, but fundamental questions remain regarding how much takes place and the impact that this might have on organisms. We asked five leading researchers in this area--working on a range of model organisms and in human disease--for their views ...
Curtin J A - - 2013
Epigenetic modifications may have a role in asthma susceptibility. To investigate whether epigenetic modification at birth of a CpG site necessary for the regulation of IL-2 transcription (IL-2 Site1) is associated with the development of asthma during childhood. Methylation of IL-2 Site1 was assessed in cord blood from 303 children ...
Balleyguier Corinne - - 2013
Breast imaging is currently at a cross-road: it is evolving in a very standardized world, surrounded by recommendations, guidelines, quality control etc. Bi-Rads categorization, with a new version expected for 2013, is one very good example of those guidelines worldwide used in breast imaging. To summarize, only a few other ...
So Melvin - - 2013
Ischemia and reperfusion injury is critical in allograft vasculopathy (AV) development. We have shown that neutrophil-mediated medial smooth muscle cell (SMC) loss precedes AV and that prolonged cold ischemia (CI) impairs medial SMC recovery and accelerates AV development. We hypothesize that neutrophils (NØs) are responsible for failed medial SMC recovery ...
Zimmerman Frederick J - - 2013
In multi-level theory, individual behavior flows from cognitive habits, either directly through social referencing, rules of thumb, or automatic behaviors; or indirectly through the shaping of rationality itself by framing or heuristics. Although behavior does not arise from individually rational optimization, it generally appears to be rational, because the cognitive ...
Atianand Maninjay K MK Division of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605, - - 2013
Recognition of microbial nucleic acids is one strategy by which mammalian hosts respond to infectious agents. Intracellular DNA that is introduced into cells during infection elicits potent inflammatory responses by triggering the induction of antiviral type I IFNs and the maturation and secretion of inflammatory cytokines, such as TNF-α, IL-1β, ...
Sfakianaki Efrosyni - - 2013
Renal scintigraphy is a powerful imaging method that provides both functional and anatomic information, which is particularly useful in the acute care setting. In our institution, for the past 2 decades, we have used a 25-minute renal diuretic protocol, technetium-99m ((99m)Tc) mercaptoacetyltriglycine with simultaneous intravenous injection of furosemide, for all ...
Shammas Amer - - 2013
Various radiopharmaceuticals are available for imaging pediatric patients in an acute care setting. This article focuses on the common applications used on a pediatric patient in acute care. To confirm the clinical diagnosis of brain death, brain scintigraphy is considered accurate and has been favorably compared with other methods of ...
Osaki Tammy H TH Department of Ophthalmology, Harvard Medical School, Ophthalmic Plastic & Reconstructive Surgery, Massachusetts Eye & Ear Infirmary, Boston, Massachusetts 02114, - - 2013
Infants with orbital hemangiomas and vascular malformations often develop expanded orbits or regional hyperostosis. Treatment in these cases depends, in part, on the stage of orbital development at the time of intervention; yet, orbital development with respect to age is not well-known. The authors sought to determine the rate of ...
Fleischer Nancy L - - 2013
Migrant farmworkers are at risk for heat-related illness (HRI) at work. The purpose of this study was to determine which risk factors could potentially reduce the prevalence of HRI symptoms among migrant farmworkers in Georgia. Trained interviewers conducted in-person interviews of adults who attended the South Georgia Farmworker Health Project ...
Hollander Seth A - - 2013
For patients with end-stage hepatic failure secondary to failing hemodynamics, combined heart-liver transplant (H-LT) remains the only option for long-term survival. We report a series of three pediatric patients who successfully underwent orthotopic H-LT for failed single-ventricle palliation. All three patients are currently living, now two, three, and five years ...
Lapar Damien J - - 2013
Efforts to reduce blood product use have the potential to avoid transfusion-related complications and reduce health care costs. The purpose of this investigation was to determine whether a multi-institutional effort to reduce blood product use affects postoperative events after cardiac surgical operations and to determine the influence of perioperative transfusion ...
Wu Tzu-Ching TC Department of Neurology, University of Texas Health Science Center, Houston, TX 77030, USA. - - 2013
Ischaemic stroke is one of the leading causes of death and disability worldwide, and intravenous alteplase is the only proven effective treatment in the acute setting. Hypothermia has been shown to improve neurological outcomes after global ischaemia-hypoxia in comatose patients who have had cardiac arrest, and is one of the ...
O'Loughlin Gillian - - 2013
Food diaries are commonly used to assess individual dietary intake in both the general and sporting populations. Despite the widespread use of such diaries, evidence suggests that individuals' self-reported energy intake frequently and substantially underestimate true energy intake. To examine the use of the Microsoft SenseCam wearable camera to help ...
Brar Preneet C - - 2013
Background. Insulin resistance increases type 2 diabetes risk in obese adolescents. Thus, quantitative tools measuring insulin sensitivity and secretion are important for risk assessment. Methods. Forty-four obese pubertal adolescents underwent oral glucose tolerance test (OGTT) and frequently sampled intravenous glucose tolerance test (FSIGT). We correlated OGTT-derived whole body sensitivity index ...
Aktürk Aysun ┼×ikar - - 2013
Anecdotal reports suggest that using retinoids with vitamin E leads to improvements of some side effects due to isotretinoin. However, vitamin E blood levels have not been reported previously in patients with acne treated with isotretinoin. We aimed to investigate the serum vitamin E levels before and after isotretinoin therapy ...
Li Ruibin R Division of NanoMedicine, Department of Medicine, University of California, Los Angeles, California 90095, United - - 2013
Functionalized carbon nanotubes (f-CNTs) are being produced in increased volume because of the ease of dispersion and maintenance of the pristine material physicochemical properties when used in composite materials as well as for other commercial applications. However, the potential adverse effects of f-CNTs have not been quantitatively or systematically explored. ...
Shewry Peter R PR Department of Plant Biology and Crop Science, Rothamsted Research , Harpenden, Hertfordshire AL5 2JQ, United - - 2013
The wheat grain comprises three groups of major components, starch, protein, and cell wall polysaccharides (dietary fiber), and a range of minor components that may confer benefits to human health. Detailed analyses of dietary fiber and other bioactive components were carried out under the EU FP6 HEALTHGRAIN program on 150 ...
Mesganaw Tehetena T Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, - - 2013
A mild and operationally simple method to synthesize diphenylhexatriene (DPH) is reported. The method relies on the Pd-catalyzed dimerization of cinnamyl acetate and provides efficient access to DPH in a single step.
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