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Woo Teri Moser - - 2013
Adolescents have access to a variety of legal or illicit substances that they use to alter their mood or "get high." The purpose of this review is to provide an overview of common substances adolescents use to get high, including the illicit substances synthetic marijuana or "Spice," salvia, MDMA, synthetic ...
Onyedika Chukwuemeka - - 2013
The evaluation for pulmonary embolism in the emergency setting has many challenges. Patients often present with symptoms that are nonspecific. Emergency Department physicians utilize their own subjective judgment or objective clinical algorithms, such as the Wells Score to assess the likelihood of the patient having PE. Other techniques, such as ...
Kerr Jacqueline - - 2013
Studies have shown relationships between important health outcomes and sedentary behavior, independent of physical activity. There are known errors in tools employed to assess sedentary behavior. Studies of accelerometers have been limited to laboratory environments. To assess a broad range of sedentary behaviors in free-living adults using accelerometers and a ...
Pacheco Paul Evan - - 2013
Esophagectomy with reconstruction using a gastric conduit is associated with a relatively high rate of anastomotic leakage. We used indocyanine green tissue angiography to evaluate the gastric conduit intraoperatively before gastroesophageal anastomosis to identify ischemia. We performed an institutional review board-approved retrospective review of all esophagectomies performed from 2010 to ...
Cosyns Bernard - - 2013
Drug-induced valvular heart disease (DIVHD) was first described in the 1960s. Initially, associations with ergot derivatives used for migraine prevention, or with anorectic drugs, were described. Drugs used for the treatment of Parkinson's disease and endocrine diseases, like hyperprolactinemia, may also induce VHD. More recently, the use of 3,4-methylendioxymetamphetamine (MDMA, ...
Hu Po-Ting - - 2013
OBJECTIVE: The aim of this study was to determine the effect of using a cane on movement time, joint moment, weight symmetry, and muscle activation patterns during sit-to-stand (STS) transfer in healthy subjects and subjects who have had a stroke. DESIGN: Nine subjects with hemiparesis (mean [SD] age, 61.11 [12.83] ...
O'Loughlin Gillian - - 2013
Food diaries are commonly used to assess individual dietary intake in both the general and sporting populations. Despite the widespread use of such diaries, evidence suggests that individuals' self-reported energy intake frequently and substantially underestimate true energy intake. To examine the use of the Microsoft SenseCam wearable camera to help ...
Brar Preneet C - - 2013
Background. Insulin resistance increases type 2 diabetes risk in obese adolescents. Thus, quantitative tools measuring insulin sensitivity and secretion are important for risk assessment. Methods. Forty-four obese pubertal adolescents underwent oral glucose tolerance test (OGTT) and frequently sampled intravenous glucose tolerance test (FSIGT). We correlated OGTT-derived whole body sensitivity index ...
Aktürk Aysun ┼×ikar - - 2013
Anecdotal reports suggest that using retinoids with vitamin E leads to improvements of some side effects due to isotretinoin. However, vitamin E blood levels have not been reported previously in patients with acne treated with isotretinoin. We aimed to investigate the serum vitamin E levels before and after isotretinoin therapy ...
Patel Snehal R - - 2013
Combining mechanical unloading by a continuous-flow left ventricular assist device (CF-LVAD) and neurohormonal blockade with heart failure medications (HFMED) is an underexplored clinical strategy to promote recovery of cardiac function in patients with advanced heart failure (HF). We implemented a clinical protocol to achieve maximal neurohormonal blockade after placement of ...
Kravchenko Julia - - 2013
Global climate change is projected to increase the frequency and duration of periods of extremely high temperatures. Both the general populace and public health authorities often underestimate the impact of high temperatures on human health. To highlight the vulnerable populations and illustrate approaches to minimization of health impacts of extreme ...
Hallowell Peter T - - 2013
With the advent of clinical fellowships in general surgery, there has been a continual debate over the effect on general surgical resident training. Will a fellowship interfere with a chief resident's experience or case volume? The aim of this study was to test the hypothesis that the presence of an ...
Few Roger - - 2013
Any analysis of how changing environmental hazards impact on public health is fundamentally constrained unless it recognizes the centrality of the social and behavioral dimensions of risk. This paper reports on a research project conducted among low-income peri-urban households in the Mekong Delta of Vietnam. The research was based on ...
Dominguez Kathleen M - - 2013
Thoracic needle decompression is lifesaving in tension pneumothorax. However, performance of subsequent tube thoracostomy is questioned. The needle may not enter the chest, or the diagnosis may be wrong. The aim of this study was to test the hypothesis that routine tube thoracostomy is not required. A prospective 2-year study ...
Fleischer Nancy L - - 2013
Migrant farmworkers are at risk for heat-related illness (HRI) at work. The purpose of this study was to determine which risk factors could potentially reduce the prevalence of HRI symptoms among migrant farmworkers in Georgia. Trained interviewers conducted in-person interviews of adults who attended the South Georgia Farmworker Health Project ...
Hollander Seth A - - 2013
For patients with end-stage hepatic failure secondary to failing hemodynamics, combined heart-liver transplant (H-LT) remains the only option for long-term survival. We report a series of three pediatric patients who successfully underwent orthotopic H-LT for failed single-ventricle palliation. All three patients are currently living, now two, three, and five years ...
Lapar Damien J - - 2013
Efforts to reduce blood product use have the potential to avoid transfusion-related complications and reduce health care costs. The purpose of this investigation was to determine whether a multi-institutional effort to reduce blood product use affects postoperative events after cardiac surgical operations and to determine the influence of perioperative transfusion ...
Wu Tzu-Ching - - 2013
Ischaemic stroke is one of the leading causes of death and disability worldwide, and intravenous alteplase is the only proven effective treatment in the acute setting. Hypothermia has been shown to improve neurological outcomes after global ischaemia-hypoxia in comatose patients who have had cardiac arrest, and is one of the ...
Anderson Brett R - - 2013
Surgical closure of ventricular septal defects remains the most common pediatric cardiac surgical procedure. No studies, however, have comprehensively analyzed risk factors and drivers of nonmortality outcomes in the current era. The purpose of this study was to assess both baseline characteristics and outcomes of children undergoing surgical repair of ...
Kelly Paul - - 2013
Technologic advances mean automated, wearable cameras are now feasible for investigating health behaviors in a public health context. This paper attempts to identify and discuss the ethical implications of such research, in relation to existing guidelines for ethical research in traditional visual methodologies. Research using automated, wearable cameras can be ...
Sever Peter - - 2013
Hypotension and syncopal attacks have been reported in association with drugs which block the renin-angiotensin-aldosterone system (RAAS). It has been proposed that the underlying mechanism is due to sensitisation of the Bezold-Jarisch reflex leading to withdrawal of sympathetic tone, profound and prolonged bradycardia, and hypotension. Sensitisation of this reflex occurs ...
Allen Thomas W - - 2013
Acute cholecystitis (AC) and lower-gastrointestinal (GI) bleeding are 2 emergencies commonly encountered in nuclear medicine. Evidence of AC on hepatobiliary scintigraphy (HBS) allows for confident diagnosis and provides support for definitive surgical treatment. Proper patient preparation is essential for HBS including fasting and the use of pharmacologic adjuncts is sometimes ...
Saha Sukamal - - 2013
The role of aberrant lymphatic drainage in changing operations for patients undergoing sentinel lymph node mapping in colon cancer has not been described on a large scale. Patients with colon cancer underwent sentinel lymph node mapping and standard oncologic resection. Aberrant lymphatic drainage was identified outside the standard resection margin, ...
Tripp Mary K - - 2013
Parents' knowledge, attitudes, and beliefs may be influenced through intervention to increase children's sun protection. Little is known about measures of these psychosocial characteristics, including psychometric properties. This paper systematically reviews parents' psychosocial measures in children's skin cancer prevention studies. A search of standard databases conducted in 2008, updated in ...
Liu R - - 2013
Tilapia is among the most common fresh water fish species raised by fish farms and can cause allergic reactions upon ingestion. To investigate important allergens in Tilapia (Oreochromis mossambicus). Allergens were detected using immunoblotting. An important allergen was purified to homogeneity by reversed-phase High Pressure Liquid Chromatography and characterized by ...
de Bruin Weller M S - - 2013
SUMMARY: Atopic dermatitis (AD) is a chronic inflammatory skin disease with a large impact on quality of life of the patients and their families. In most cases, the diagnosis of AD can easily be made based on (family) history and clinical examination. If necessary, a practical set of diagnostic criteria ...
Husain Zain - - 2013
Food allergies have become a significant medical and legal concern for children worldwide, as there is a rising incidence of potentially fatal hypersensitivity reactions. The most common foods implicated include cow milk, wheat, egg, soy, peanut, tree nuts such as walnuts, hazelnuts, almonds, cashews, pecans, and pistachios, fish and shellfish. ...
Harris Jenine K - - 2013
Using evidence-based strategies within U.S. local health departments (LHDs) to provide community services can increase the likelihood of success and efficient use of resources. Dissemination of such strategies, a necessary precursor to implementation, occurs through networks of relationships and can be facilitated by weak network ties, whereas implementation is associated ...
Ramsay Alan D - - 2013
Over the last 30 years there has been a massive change in both the clinical and pathologic aspects of malignant lymphomas. Pathologists are now able to evaluate cellular phenotypes and lineages of tumor cells using a wide variety of biomarkers and molecular techniques. The ability to identify tumor cell phenotypes ...
Ramírez E - - 2013
Previous research has shown that gastric acid suppression by antacid drugs can promote allergic reactions to acid-labile food proteins. No data are available about whether antacid drugs can promote drug hypersensitivity reactions. The most potent and longer lasting inhibition of gastric secretion is provided by proton pump inhibitors (PPIs). We ...
Ateah Christine A - - 2013
The purpose of this pilot project was to determine first-time expectant parents' perceptions of a parent education intervention, their education needs, and preferred sources and modes of such education. The intervention was carried out during the last class of a public health prenatal education series. A total of 31 first-time ...
Goyal R K - - 2013
Recent studies with genetic deletion of P2Y1 receptor (P2Y1-/-) have clinched its role in enteric purinergic inhibitory neurotransmission and suggested that β-NAD may be the purinergic inhibitory neurotransmitter in the colon. In this issue of the Journal, Gil and colleagues extend their earlier observations to the cecum and gastric antrum, ...
Koid Suang S - - 2013
Despite its long history, the renin-angiotensin system remains an active area of research. New components and interactions between novel and established components continue to be discovered. These developments are providing fresh insight into the role of the renin-angiotensin system in cardiovascular health and disease and new therapeutic targets for the ...
Núñez-Córdoba Jorge M - - 2013
Obesity has become a major health and economic problem with increasing prevalence. Unfortunately, no country can act as public health exemplar for reduction of obesity. The finding of associations between sedentary behaviors and obesity, independent of the level of physical activity, may offer new insights to prevent this burdensome problem. ...
Man Stephen - - 2013
The early 1990s saw the first clinical testing of several therapeutic cancer vaccines. There was great optimism that these vaccines could be used as an alternative therapy for patients who had failed to respond to conventional cancer therapies. This article provides a personal perspective on the cancer vaccine field after ...
Harb H - - 2013
Oral supplementation with probiotic bacteria can protect against the development of allergic and inflammatory diseases. The aim of this study was to investigate potential immunomodulatory and allergy-protective effects of processed Lactobacillus rhamnosus GG (LGG)-derived supernatants early in life in neonatal mice. In vitro, RAW264.7 mouse macrophages were stimulated with viable ...
Flint Lisa - - 2013
This feature looks at changing the format of a well-established information skills session for first-year biochemistry students at UCL, to improve its design, delivery and the overall learning experience for the students. After reviewing current literature, active learning methods were explored and an idea of a research-based quiz based on ...
Hamaji Masatsugu - - 2013
To clarify the perioperative and oncologic outcome of pulmonary resection for a metachronous second primary lung cancer (MSPLC) following resection of an initial non-small cell lung cancer (NSCLC). Retrospective chart review identified 161 patients (88 men and 73 women) with a median age of 70 years (range, 34-88 years) who ...
Taggarshe Deepa - - 2013
Colorectal cancer (CRC) is increasing in young patients. We aimed to assess the trends of CRC and its corresponding clinical presentation in the young. Cancer registry patients were divided into 3 groups according to age:<50, 50-75, and >75 years. Charts were reviewed for average-risk patients <50 years of age to assess ...
Eghtesady Pirooz - - 2013
Several efforts are under way to conduct quality-improvement initiatives in pediatric cardiology and cardiac surgery. Our goal was to develop an objective prioritization scheme for such initiatives based on encounter frequency and relative contribution of quality measures of morbidity (and associated variances), particularly in the setting of low mortality. We ...
Love Charito - - 2013
Although infection may be suggested by signs and symptoms such as fever, pain, general malaise, and abnormal laboratory results, imaging tests often are used to confirm its presence. Morphologic imaging tests identify structural alterations of tissues or organs that result from a combination of microbial invasion and the inflammatory response ...
Shammas Amer - - 2013
Various radiopharmaceuticals are available for imaging pediatric patients in an acute care setting. This article focuses on the common applications used on a pediatric patient in acute care. To confirm the clinical diagnosis of brain death, brain scintigraphy is considered accurate and has been favorably compared with other methods of ...
Mack Karin A - - 2013
From 1992 to 1999, an average of more than 18,000 unintentional home injury deaths occurred in the U.S. annually. The objective of this study was to provide current prevalence estimates of fatal unintentional injury in the home. Data from the 2000-2008 National Vital Statistics System were used in 2011 to ...
Aguilar-Cazares Dolores - - 2013
Lung cancer is the leading cause of cancer death worldwide and non-small cell lung carcinoma (NSCLC) is the most common type of lung carcinomas. In adenocarcinomas, the most frequent histologic type of NSCLC, dendritic cells (DCs) are localized in close contact with tumor cells, and tumor-infiltrating lymphocytes (TILs) are observed ...
Erbas B - - 2013
Few studies have focused on pollen exposure and asthma in children. None have examined associations between persistent exposure to pollen in infancy and aeroallergen sensitisation and asthma in childhood. To examine the association between higher ambient levels of pollen in the first 3-6 months of life and risk of eczema, sensitization ...
Macfarlane Fraser - - 2013
Change efforts in healthcare sometimes have an ambitious, whole-system remit and seek to achieve fundamental changes in norms and organisational culture rather than (or as well as) restructuring the service. Long-term evaluation of such initiatives is rarely undertaken. We report a secondary analysis of data from an evaluation of a profound institutional ...
Bratke K - - 2013
Plasmacytoid dendritic cells (pDCs) infiltrate sites of acute Th2-dominant inflammation, but their role in allergic asthma remains unclear. To characterize circulating pDCs from patients with allergic asthma outside their respective allergen season. Adhesion molecules, co-stimulatory molecules, immunoglobulin receptors and chemokine receptors were quantified on blood pDCs from 20 patients with ...
Tang Min Moon - - 2013
Background  Psoriasis is an immune-mediated, chronic, inflammatory skin disease which affects approximately 2% of the world's population. It has a major impact on the patient's quality of life (QoL), influencing career, social activities, family relationships, and all other aspects of life. Many studies have described the various ways in which ...
Curtin J A - - 2013
Epigenetic modifications may have a role in asthma susceptibility. To investigate whether epigenetic modification at birth of a CpG site necessary for the regulation of IL-2 transcription (IL-2 Site1) is associated with the development of asthma during childhood. Methylation of IL-2 Site1 was assessed in cord blood from 303 children ...
Balleyguier Corinne - - 2013
Breast imaging is currently at a cross-road: it is evolving in a very standardized world, surrounded by recommendations, guidelines, quality control etc. Bi-Rads categorization, with a new version expected for 2013, is one very good example of those guidelines worldwide used in breast imaging. To summarize, only a few other ...
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