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Aguilar-Cazares Dolores - - 2013
Lung cancer is the leading cause of cancer death worldwide and non-small cell lung carcinoma (NSCLC) is the most common type of lung carcinomas. In adenocarcinomas, the most frequent histologic type of NSCLC, dendritic cells (DCs) are localized in close contact with tumor cells, and tumor-infiltrating lymphocytes (TILs) are observed ...
Erbas B - - 2013
Few studies have focused on pollen exposure and asthma in children. None have examined associations between persistent exposure to pollen in infancy and aeroallergen sensitisation and asthma in childhood. To examine the association between higher ambient levels of pollen in the first 3-6 months of life and risk of eczema, sensitization ...
Berry Beverley B Library and Information Manager, Royal College of Psychiatrists, LondonBermuda Hospital Board, King Edward VII Memorial Hospital, Health Sciences Library, Paget, - - 2013
This is the 5th in a series of articles exploring international trends in health science librarianship in Latin America and the Caribbean in the first decade of the 21st century. The invited authors are from Argentina, Bermuda and Mexico. Future issues will track trends in Central Europe and the Middle ...
Macfarlane Fraser - - 2013
Change efforts in healthcare sometimes have an ambitious, whole-system remit and seek to achieve fundamental changes in norms and organisational culture rather than (or as well as) restructuring the service. Long-term evaluation of such initiatives is rarely undertaken. We report a secondary analysis of data from an evaluation of a profound institutional ...
Lev-Ran Shaul - - 2013
The association between substance use disorders (SUDs) and mental illness (MI) has been well established. Previous studies reporting this association in various clinical populations have not taken into account former substance use. This may be important as increased prevalence of substance use among individuals with MI may partially explain the ...
Guo Min - - 2013
Nontranslational functions of vertebrate aminoacyl tRNA synthetases (aaRSs), which catalyze the production of aminoacyl-tRNAs for protein synthesis, have recently been discovered. Although these new functions were thought to be 'moonlighting activities', many are as critical for cellular homeostasis as their activity in translation. New roles have been associated with their ...
El Enany Nellie - - 2013
Policy makers increasingly regard user involvement as an important dimension of service development. However, research suggests user involvement is often unrepresentative and tokenistic. Drawing on an in-depth case study in mental health carried out in 2008-2012, we examine the processes that give rise to unrepresentative service user involvement. We show ...
Tripp Mary K - - 2013
Parents' knowledge, attitudes, and beliefs may be influenced through intervention to increase children's sun protection. Little is known about measures of these psychosocial characteristics, including psychometric properties. This paper systematically reviews parents' psychosocial measures in children's skin cancer prevention studies. A search of standard databases conducted in 2008, updated in ...
Liu R - - 2013
Tilapia is among the most common fresh water fish species raised by fish farms and can cause allergic reactions upon ingestion. To investigate important allergens in Tilapia (Oreochromis mossambicus). Allergens were detected using immunoblotting. An important allergen was purified to homogeneity by reversed-phase High Pressure Liquid Chromatography and characterized by ...
Riezebos-Brilman Annelies - - 2013
Hepatitis E virus (HEV) genotype 3 has been identified in patients with autochthonous HEV infections in developed countries and is currently being recognized as an emerging zoonotic pathogen. HEV infection may lead to a chronic hepatitis in immune-compromised patients. We studied the incidence of HEV in adult lung transplant recipients ...
Goldstone Andrew B AB Department of Surgery, Division of Cardiovascular Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, - - 2013
Minimally invasive approaches to mitral valve surgery are increasingly used, but the surgical approach must not compromise the clinical outcome for improved cosmesis. We examined the outcomes of mitral repair performed through right minithoracotomy or median sternotomy. Between January 2002 and October 2011, 1011 isolated mitral valve repairs were performed ...
Jenmalm M C - - 2013
The increasing allergy prevalence in affluent countries may be caused by reduced microbial stimulation and a decreased dietary ω-3/ω-6 long-chain polyunsaturated fatty acid (LCPUFA) ratio, resulting in an abnormal postnatal immune maturation. The timing of allergy-preventive probiotic and ω-3 LCPUFA interventions is critical, as early-life events occurring during critical windows ...
Kaczmarek Ingo - - 2013
Despite improvements in immunosuppressive therapy, the most advantageous combination for cardiac transplant recipients has not been established. This randomized controlled trial was performed to evaluate the efficacy and safety of 3 immunosuppressive protocols. Between 2003 and 2005, 78 de novo cardiac transplant recipients were randomized 2:2:1 to receive steroids and ...
Gann Bob - - 2013
In 2013 the NHS Commissioning Board launches its new integrated customer service platform. The new service utilises the full range of channels (web, telephone, apps etc) to provide access to information to support transparency, participation and transactions. Digital health services have proven benefits in informed choice, shared decision making and ...
Ottuso Patrick - - 2013
Numerous aquatic vertebrate species are known to cause cutaneous injury. While many of the injuries occur in regions that harbor such organisms, with the ability of people to travel long distances in short periods of time, these injuries may be seen worldwide. Also, with the increasing tendency of people to ...
Song Minkyoung - - 2013
Participation in physical activity brings health benefits for adolescents. However, limited data are available on the percentage of U.S. adolescents who engage in levels of aerobic and muscle-strengthening activities recommended in the 2008 Physical Activity Guidelines for Americans (2008 Guidelines). To examine the prevalence at which U.S. adolescents aged 12-17 ...
Zadra Antonio A Center for Advanced Research in Sleep Medicine, Hôpital du Sacré-Cœur de Montréal, Montreal, QC, Canada; Department of Psychology, Université de Montréal, Montreal, QC, - - 2013
Somnambulism, or sleepwalking, can give rise to a wide range of adverse consequences and is one of the leading causes of sleep-related injury. Accurate diagnosis is crucial for proper management and imperative in an ever-increasing number of medicolegal cases implicating sleep-related violence. Unfortunately, several widely held views of sleepwalking are ...
Mota-Burgos Ana - - 2013
Birt-Hogg-Dubé syndrome (BHDS) is an autosomal dominant genodermatosis characterized by the presence of three skin tumors (fibrofolliculomas, trichodiscomas, and acrochordons), together with an increased risk for other tumors, especially renal tumors, caused by a mutation in folliculin, an oncogene suppressor protein. The association of this syndrome with melanoma is very ...
Hoehner Christine M CM Division of Public Health Sciences and Alvin J. Siteman Cancer Center, School of Medicine, Washington University in St. Louis, St. Louis, MO 63110, USA. - - 2013
Systematic reviews of public health interventions are useful for identifying effective strategies for informing policy and practice. The goals of this review were to (1) update a previous systematic review of physical activity interventions in Latin America which found that only school-based physical education had sufficient evidence to recommend widespread ...
Koid Suang S - - 2013
Despite its long history, the renin-angiotensin system remains an active area of research. New components and interactions between novel and established components continue to be discovered. These developments are providing fresh insight into the role of the renin-angiotensin system in cardiovascular health and disease and new therapeutic targets for the ...
Hamaji Masatsugu - - 2013
To clarify the perioperative and oncologic outcome of pulmonary resection for a metachronous second primary lung cancer (MSPLC) following resection of an initial non-small cell lung cancer (NSCLC). Retrospective chart review identified 161 patients (88 men and 73 women) with a median age of 70 years (range, 34-88 years) who ...
Molina Patricia E PE Department of Physiology and Alcohol and Drug Abuse Center of Excellence, Louisiana State University Health Science Center, New Orleans, LA, USA. - - 2013
Traumatic injury ranks as the number one cause of death for the younger than 44 years age group and fifth leading cause of death overall (www.nationaltraumainstitute.org/home/trauma_statistics.html). Although improved resuscitation of trauma patients has dramatically reduced immediate mortality from hemorrhagic shock, long-term morbidity and mortality continue to be unacceptably high during ...
Stockbridge Norman N Division of Cardiovascular and Renal Products, Center for Drug Evaluation and Research, US FDA, Silver Spring, MD, - - 2013
Drug-induced torsade de pointes (TdP) is a potentially fatal iatrogenic entity. Its reporting rate in association with non-cardiac drugs increased exponentially from the early 1990s and was associated with an increasing number of new non-cardiac drugs whose proarrhythmic liability was not appreciated pre-marketing. This epidemic provoked a comprehensive global response ...
Dominguez Kathleen M - - 2013
Thoracic needle decompression is lifesaving in tension pneumothorax. However, performance of subsequent tube thoracostomy is questioned. The needle may not enter the chest, or the diagnosis may be wrong. The aim of this study was to test the hypothesis that routine tube thoracostomy is not required. A prospective 2-year study ...
Zuckier Lionel S - - 2013
Two categories of single-photon radiopharmaceuticals for brain perfusion exist, nonlipophilic and lipophilic compounds. The former are useful in performing simple flow examinations which today have application primarily in the determination of brain death. The latter also exhibit a parenchymal uptake phase that allows for evaluation of the distribution of blood ...
Aronson Jeffrey K JK Department of Primary Care Health Sciences, New Radcliffe House, Radcliffe Observatory Quarter, Woodstock Road, Oxford, OX2 6GG, UK. - - 2013
The terms 'adverse drug effects' and 'adverse drug reactions' are commonly used interchangeably, but they have different implications. Adverse drug reactions arise when a compound (e.g. a drug or metabolite, a contaminant or adulterant) is distributed in the same place as a body tissue (e.g. a receptor, enzyme, or ion ...
Toole Geraldine A GA Institute of Food Research , Norwich Research Park, Norwich NR4 7UA, United - - 2013
Dough-derived cell wall fragments isolated by ultracentrifugation were largely derived from the starchy endosperm, with some fragments deriving from the aleurone and outer layers, as indicated by fluorescence microscopy. Dough mixing had little effect on the structure and composition of cell wall fragments compared to thin grain sections, as determined ...
de Bruin Weller M S - - 2013
SUMMARY: Atopic dermatitis (AD) is a chronic inflammatory skin disease with a large impact on quality of life of the patients and their families. In most cases, the diagnosis of AD can easily be made based on (family) history and clinical examination. If necessary, a practical set of diagnostic criteria ...
Nwogu Chukwumere E CE Department of Thoracic Surgery, Roswell Park Cancer Institute, Buffalo, NY 14263, USA. - - 2013
Lymph node staging provides critical information in patients with non-small cell lung cancer (NSCLC). Lymphangiogenesis may be an important contributor to the pathophysiology of lymphatic metastases. We hypothesized that the presence of lymph node micrometastases positively correlates with vascular endothelial growth factors (VEGFs) A, C, and D as well as ...
Patel Snehal R - - 2013
Combining mechanical unloading by a continuous-flow left ventricular assist device (CF-LVAD) and neurohormonal blockade with heart failure medications (HFMED) is an underexplored clinical strategy to promote recovery of cardiac function in patients with advanced heart failure (HF). We implemented a clinical protocol to achieve maximal neurohormonal blockade after placement of ...
Jacobs Jordan V - - 2013
The short-term safety of percutaneous dilatational tracheostomy has been widely demonstrated. However, less is known about their long-term complications. Through an illustrative case series, we present and define "corkscrew stenosis," a type of tracheal stenosis uniquely associated with percutaneous dilatational tracheostomy. Patients treated at our institution for tracheal stenosis after ...
Cherpitel Cheryl J CJ Alcohol Research Group, Emeryville, CA 94608, USA. - - 2013
While a substantial literature exists demonstrating a strong association of alcohol and intentional injury, less is known about the association of intentional injury with recreational drug use, either alone, or in combination with alcohol. The risk of intentional injury due to alcohol and other drug use prior to injury is ...
Torrazza Roberto Murgas RM Division of Neonatology, Department of Pediatrics, University of Florida College of Medicine, 1600 Southwest Archer Road, Box 100296, HD Building Room 112, Gainesville, FL 32610-0296, - - 2013
Current evidence highlights the importance of developing a healthy intestinal microbiota in the neonate. Many aspects that promote health or disease are related to the homeostasis of these intestinal microbiota. Their delicate equilibrium could be strongly influenced by the intervention that physicians perform as part of the medical care of ...
Anderson Brett R - - 2013
Surgical closure of ventricular septal defects remains the most common pediatric cardiac surgical procedure. No studies, however, have comprehensively analyzed risk factors and drivers of nonmortality outcomes in the current era. The purpose of this study was to assess both baseline characteristics and outcomes of children undergoing surgical repair of ...
Kang W Y WY Department of Radiology, Anam Hospital, College of Medicine, Korea University, Seoul, Republic of - - 2013
The purpose of our study was to assess the extrarenal length of renal arterial branches and tumour-feeding arteries on multidetector CT (MDCT) angiography, in addition to the perihilar branching patterns, with relevance to segmental artery clamping. MDCT angiograms of 64 patients with renal masses <4 cm were retrospectively reviewed by ...
Husain Zain - - 2013
Food allergies have become a significant medical and legal concern for children worldwide, as there is a rising incidence of potentially fatal hypersensitivity reactions. The most common foods implicated include cow milk, wheat, egg, soy, peanut, tree nuts such as walnuts, hazelnuts, almonds, cashews, pecans, and pistachios, fish and shellfish. ...
Hallowell Peter T - - 2013
With the advent of clinical fellowships in general surgery, there has been a continual debate over the effect on general surgical resident training. Will a fellowship interfere with a chief resident's experience or case volume? The aim of this study was to test the hypothesis that the presence of an ...
Gurrin Cathal - - 2013
The Microsoft SenseCam, a small camera that is worn on the chest via a lanyard, increasingly is being deployed in health research. However, the SenseCam and other wearable cameras are not yet in widespread use because of a variety of factors. It is proposed that the ubiquitous smartphones can provide ...
Woo Teri Moser - - 2013
Adolescents have access to a variety of legal or illicit substances that they use to alter their mood or "get high." The purpose of this review is to provide an overview of common substances adolescents use to get high, including the illicit substances synthetic marijuana or "Spice," salvia, MDMA, synthetic ...
Onyedika Chukwuemeka - - 2013
The evaluation for pulmonary embolism in the emergency setting has many challenges. Patients often present with symptoms that are nonspecific. Emergency Department physicians utilize their own subjective judgment or objective clinical algorithms, such as the Wells Score to assess the likelihood of the patient having PE. Other techniques, such as ...
Trang Nguyen H H D - - 2013
Sedentary behavior is associated with increased risk of chronic disease and sedentary behavior is increasing among adolescents. Data on changes in sedentary behavior in developing countries are limited. To describe 5-year longitudinal changes in nonschool sedentary hours among urban adolescents in Ho Chi Minh City, and to identify correlates with ...
El-Shazly A E - - 2013
Recent data indicated that natural killer (NK) cells and chemokines could play a pivotal role in nasal inflammation. CX3CR1, the only receptor for fractalkine/CX3CL1, is abundantly expressed by NK cells, and was recently shown to also be a receptor for eotaxin-3/CCL26. However, no reports explored the NK cells-CX3CL1-CCL26 axis via ...
Herbert Paul - - 2013
The use of intranets as knowledge management tools in the NHS has been applied with varying success. This study set out to evaluate the effectiveness of the NHS Lanarkshire intranet site FirstPort as a knowledge management tool and to capture opinions on what would be required of a new FirstPort ...
Veraldi Stefano - - 2013
Hookworm-related cutaneous larva migrans (CLM) is characterized clinically by erythematous and slightly raised tracks, located especially on the feet. These tracks may be single or multiple, linear or serpiginous, more or less ramified and intertwined. The length is variable (up to many cm); the width ranges from 1 mm to 4 mm. ...
Calsyn Donald A DA Alcohol and Drug Abuse Institute, University of Washington, Seattle, WA 98105, USA. - - 2013
For substance abuse treatment-seekers engaging in high risk sexual behavior, their inconsistent condom use may be related to their condom use attitudes and skills. This study compared treatment-seeking male and female substance abusers in their reported barriers to condom use and condom use skills. Men and women (N = 1,105) ...
Saha Sukamal - - 2013
The role of aberrant lymphatic drainage in changing operations for patients undergoing sentinel lymph node mapping in colon cancer has not been described on a large scale. Patients with colon cancer underwent sentinel lymph node mapping and standard oncologic resection. Aberrant lymphatic drainage was identified outside the standard resection margin, ...
Liu Shuanglong S Department of Radiology, Keck School of Medicine, Molecular Imaging Center, University of Southern California, Los Angeles, CA 90033, - - 2013
18F positron emission tomography (PET) has a number of attributes that make it clinically attractive, including nearly 100% positron efficiency, very high specific radioactivity, and a short half-life of ≈ 110 minutes. However, the short half-life of 18F and the poor nucleophilicity of fluoride introduce challenges for the incorporation of ...
Heyn Lena - - 2013
: Patients are experts of their own symptoms and worries, but tend not to express their concerns spontaneously in the consultation. Even when emotions are brought up, they are discussed briefly. : The objective of this study was to examine the impact of an interactive tailored patient assessment (Choice) on ...
Ahn Roy - - 2013
Human trafficking is an increasingly well-recognized human rights violation that is estimated to involve more than 2 million victims worldwide each year. The health consequences of this issue bring victims into contact with health systems and healthcare providers, thus providing the potential for identification and intervention. A robust healthcare response, ...
Mallya Ashok A The Bell Street Clinic Opioid Treatment Program (OTP), Mental Health Service, John Cochran Hospital, St. Louis VA Medical Center, St. Louis, MO, - - 2013
Clinics licensed to provide pharmacotherapy for opiate dependence disorder are required to perform random urine drug screen (RUDS) tests. The results provide the empirical basis of individual treatment and programmatic effectiveness, and public health policy. Patients consent to witnessed testing but most tests are unwitnessed. The purpose of the present ...
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