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Results 401 - 450 of 3474
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Crowther Mark A - - 2013
Medical thromboprophylaxis reduces venous thromboembolism (VTE), while causing bleeding. Routine application of pharmacological VTE prophylaxis to low risk medical patients is likely to cause net harm; as a result only moderate or high risk patients should be exposed to VTE prophylaxis. To avoid unneeded exposure to VTE prophylaxis health care ...
Knight Kelly R - - 2013
Episodic (less than weekly) drug use and binge drinking increase HIV-related sexual risk behaviors among men who have sex with men (MSM), yet no evidence-based interventions exist for these men. We describe an adaptation process of the Personalized Cognitive Counseling (PCC) intervention for utilization with high-risk, HIV-negative episodic, substance-using MSM. ...
Moret Séverine - - 2013
In water, spin-lattice relaxation times (T(1)) and calibration curves for chemical shifts have been determined for the (13)C and the (1)H(C) atoms in HCOOH, HCOONa, CO(2), Na(2)CO(3) and NaHCO(3) by NMR spectroscopy. These data facilitate kinetic and mechanistic studies for H(2) storage/delivery in the carbon dioxide-formic acid systems under H(2) ...
Farrow N - - 2013
Genetic therapies for cystic fibrosis (CF) must be assessed for safety and efficacy, so testing in a non-human primate (NHP) model is invaluable. In this pilot study we determined if the conducting airways of marmosets (n = 2) could be transduced using an airway pre-treatment followed by an intratracheal bolus ...
Garcia Sandra N - - 2013
Cytotoxicity measurements are often performed to evaluate the biocompatibility of medical device materials. Here, we describe the use of a real-time cell analyzer (RTCA) system for the investigation of biocompatibility of medical devices by comparing RTCA results to two distinct methods described in the International Organization for Standardization (ISO) guidelines. ...
Bosetti Michela - - 2013
The importance of the complex interrelated regulatory pathways involving IGF factors and pancreatic hormones can be observed in several metabolic diseases, where the deregulation of these factors has a wide impact on bone health. These findings have stimulated us to compare the effect of IGF-I, IGF-II, insulin and preptin on ...
Alekseyev Aleksey B - - 2013
The multireference spin-orbit (SO) configuration interaction (CI) method in its Λ-S contracted SO-CI version is employed to calculate two-dimensional potential energy surfaces for the ground and low-lying excited states of CF(3)I relevant to its photodissociation in the lowest absorption band (A band). The computed equilibrium geometry for the X[combining tilde]A(1) ...
Matar Hosam E HE Nuclear Medicine, Royal Free Hospital, Pond Street, London, NW3 2QG, UK. - - 2013
The purpose of this study was to assess the value of SPECT/CT imaging in patients with chronic spinal pain. This was a retrospective consecutive study. Patients with chronic neck or back pain from outpatient spinal clinics with clinical features raising the possibility of a facetogenic pain generator and non-conclusive MRI/CT ...
Kudlicka Aleksandra - - 2013
Executive functioning is frequently impaired among people with Parkinson's disease (PD). Little is known about awareness of executive functioning, in the sense of being able to accurately appraise functioning or performance, in people with PD, or about whether awareness is particularly affected in those who have impaired executive functioning. This ...
Schaller Benoît - - 2013
The broad resonances underlying the entire (1) H NMR spectrum of the brain, ascribed to macromolecules, can influence metabolite quantification. At the intermediate field strength of 3 T, distinct approaches for the determination of the macromolecule signal, previously used at either 1.5 or 7 T and higher, may become equivalent. The aim ...
Oró-Solé Judith - - 2013
The correlated anion order in the oxynitride perovskite NdVO(2)N, where disordered zig-zag VN chains segregate into planes within a pseudo-cubic lattice, is similar to that in materials such as SrTaO(2)N containing d(0) transition metal cations. However, NdVO(2)N has 3d(1) V(4+) cations and the 3d-electrons are itinerant, showing that the anion ...
Ghasemipour Yadollah - - 2013
This study examined how mindfulness and integrative self-knowledge were related to health-related issues. Men in general population (n = 103) and coronary heart disease samples (n = 101) completed the Mindful Attention Awareness Scale, the Integrative Self-knowledge Scale, the Type 2 subscale of the Interpersonal Reactions Inventory, the Perceived Stress Scale, and the Anxiety ...
Igari Kimihiro - - 2013
Purpose: To determine the influence of the abdominal aortic aneurysm (AAA) anatomy on the clinical outcomes after endovascular AAA repair (EVAR). Methods: Between January 2008 and December 2010, 53 patients underwent EVAR. The parameters outside of the device instructions for use (IFU) were: short neck length (<15 mm), proximal neck ...
Pfandler Edina - - 2013
This study explored children's development in comprehending four types of pointing gestures with different familiarity. Our aim was to highlight human infants' pointing comprehension abilities under the same conditions used for various animal species. Sixteen children were tested longitudinally in a two-choice task from 1 year of age. At the age ...
Licina Derek - - 2013
BACKGROUND: United States foreign policy is tied extensively to health initiatives, many related to the use of military assets. Despite substantial resource investment by the US Department of Defense (DoD) in hospital ship humanitarian assistance and disaster response missions, the impact of this investment is unclear. METHODS: A systematic literature ...
Jiang Ling - - 2013
Expression of miR-34c is significantly reduced in human endometrial cancer cells and miR-34c regulates multiple genes associated with cancer cell proliferation, apoptosis and invasiveness. Thus, miR-34c can theoretically become a target that enhances chemotherapy. Upregulation of miR-34c to enhance the chemotherapeutic effect of cisplatin (DDP) has not been studied in ...
Kim Yungkun - - 2013
Craniomandibular traits of the water deer from the Korean peninsula were examined to assess size change in growth between age groups and sexes. Univariate and multivariate analyses were conducted based on 34 cranial and 11 mandibular measurements from both sexes. Statistical comparisons of skull measurements revealed a significantly different growth ...
Lin Na - - 2013
Abstract Background: Maple syrup urine disease (MSUD) is an inherited disorder caused by a deficiency of the mitochondrial branched-chain keto acid dehydrogenase complex. We investigated whether liquid chromatography-tandem mass spectrometry (LC-MS/MS) is a more reliable and accurate method than MS/MS in the diagnosis and management of patients with MSUD in ...
Isa Fatima - - 2013
BACKGROUND: The epidemiologic evidence on the role of dietary consumption on the risk of bladder cancer in the Chinese population is limited. We investigated the role of dietary consumption and diet diversity on the risk of developing bladder cancer within a Chinese population. METHODS: A case-control study of 487 cases ...
Okada Yuko - - 2013
Purpose: This study aimed to determine if preoperative time course changes in serum C-reactive protein (CRP) levels can predict clinical outcome of surgical intervention for active infective endocarditis. Methods: Surgically treated patients (n = 109) with active infective endocarditis were reviewed retrospectively. We divided the patients into 2 subgroups according ...
Teshima Hideki - - 2013
A 32-year-old female patient presented with shortness of breath. The patient had received aortic valve replacement with a 25-mm bioprosthetic valve at the age of 22, and had had two babies, postoperatively. Ten years later, echocardiography showed the calcifi ed bioprosthetic valve with a high peak pressure gradient (70 mmHg) ...
Hormann Jan - - 2013
The Cu(ii) complexes of cyclen and two of its heterosubstituted analogues were shown to be efficient oxidative DNA cleavers. The reactivity strongly depends on the heteroatom inserted into the macrocycle (O > S > N).
Schwab Inessa I Institute of Genetics, Department of Biology, University of Erlangen-Nürnberg, Erwin-Rommelstrasse 3, 91058 Erlangen, - - 2013
Intravenous immunoglobulin (IVIG) preparations comprise pooled IgG antibodies from the serum of thousands of donors and were initially used as an IgG replacement therapy in immunocompromised patients. Since the discovery, more than 30 years ago, that IVIG therapy can ameliorate immune thrombocytopenia, the use of IVIG preparations has been extended ...
Elsafi Salah H - - 2013
Giardia lamblia and Cryptosporidium parvum are recognized as the most common protozoan infections in Saudi Arabia. Microscopic examination of stool samples, either direct or concentrated, for the recovery of G. lamblia cysts and trophozoites and C. parvum oocysts is still the most commonly used for the diagnosis of both parasites. ...
Guérillon Claire - - 2013
Inhibitor of Growth 1 (ING1) was identified and characterized as a "candidate" tumor suppressor gene in 1996. Subsequently, four more genes, also characterized as "candidate" tumor suppressor genes, were identified by homology search: ING2, ING3, ING4, and ING5. The ING proteins are characterized by a high homology in their C-terminal ...
Balke Maurice - - 2013
Indications for acromioplasty are based on clinical symptoms and are generally supported by typical changes in acromial morphology on standard radiographs. We evaluated 5 commonly used radiographic parameters of acromial morphology and assessed the association between different radiographic characteristics on the one hand and subacromial impingement or rotator cuff tears ...
Fayer Ronald - - 2013
A proof of concept study was conducted to determine if transparent double-sided adhesive tape could be used to recover and detect [by polymerase chain reaction (PCR) and immunofluorescence microscopy (IFA)] Cryptosporidium parvum oocysts on fresh produce and on a food preparation surface. Oocysts were applied on the surface of ten ...
Morgan Stuart - - 2013
Abstract Decision tree induction is a novel approach to exploring attacker-defender interactions in many sports. In this study hockey was chosen as an example to illustrate the potential use of decision tree inductions for the purpose of identifying and communicating characteristics that drive the outcome. Elite female players performed one-versus-one ...
Manimmanakorn Apiwan - - 2013
The aim was to investigate the effects of low-load resistant training combined with vascular occlusion or normobaric hypoxic exposure, on neuromuscular function. In a randomised controlled trial, well-trained athletes took part in a 5-week training of knee flexor/extensor muscles in which low-load resistant exercise (20 % of one repetition maximum, 1-RM) ...
Spitters Tim W G M - - 2013
In cartilage tissue engineering bioreactors can create a controlled environment to study chondrocyte behavior under mechanical stimulation or produce chondrogenic grafts of clinically relevant size. Here we present a novel bioreactor, which combines mechanical stimulation with a two compartment system through which nutrients can be supplied solely by diffusion from ...
Schwiedrzik J J - - 2013
Nonlinear computational analysis of materials showing elasto-plasticity or damage relies on knowledge of their yield behavior and strengths under complex stress states. In this work, a generalized anisotropic quadric yield criterion is proposed that is homogeneous of degree one and takes a convex quadric shape with a smooth transition from ...
Rodriguez Mosquera Patricia M - - 2013
We studied the relationship between perceived social image and life satisfaction in four different cultural groups. One-hundred nine Indian (63 females, 46 males), 67 Pakistani/Bangladeshi (36 females, 31 males), 76 White British (43 females, 33 males), and 94 European Americans (43 females, 48 males) completed measures on the cultural importance of ...
Kang Suk - - 2013
Bifocal disruption of the knee extensor mechanism is a rare injury. Bifocal proximal and distal avulsion fracture of the patella tendon is extremely rare in adults. Here, the authors report the case of an 84-year-old male patient who developed simultaneous avulsion fracture of the patella tendon from the inferior pole ...
Saikia Nabanita - - 2013
The potential biomedical application of carbon nanotubes (CNTs) pertinent to drug delivery is highly manifested considering the remarkable electronic and structural properties exhibited by CNT. To simulate the interaction of nanomaterials with biomolecular systems, we have performed density functional calculations on the interaction of pyrazinamide (PZA) drug with functionalized single-wall ...
Asayama S - - 2013
OBJECTIVES: To explore the possibility of a generally applicable tool for the immediate diagnosis of Parkinson's disease (PD) in its early stage, we compared the sensitivity and specificity of an acute levodopa challenge test with that of (123) I-metaiodobenzylguanidine (MIBG) myocardial scintigraphy. MATERIALS AND METHODS: A consecutive series of 45 ...
Ambre Avinash H - - 2013
In this work, novel modified nanoclays were used to mineralize hydroxyapatite (HAP) mimicking biomineralization in bone. This in situ HAPclay was further incorporated into chitosan/polygalacturonic acid (Chi/PgA) scaffolds and films for bone tissue engineering. Differences in microstructure of the scaffolds were observed depending on the changes in processing of in ...
Saito Yu - - 2013
PURPOSE: The function of regulatory T cells (Foxp3(+)CD4(+)CD25(+) T cells: T(reg)) after surgery remains unspecified. We investigated the potential role of T(reg) as a new stress marker for various operations. METHODS: Thirty-three patients who underwent various operations at our department were divided into the following three groups based on the ...
Hu Jian-Li - - 2013
Induction of HO-1 protein can have both beneficial and detrimental effects for cells, including regulating proliferation and apoptosis of several tumors. We have investigated the regulation of HO-1, p38MAPK and mTOR in the context of proliferation, cell cycle events and apoptosis of esophageal squamous cell carcinoma cells. Real-time PCR and ...
Wilson-Robles H M - - 2013
Tumour-initiating cells (TICs) have been identified in many solid human tumours, including malignant melanoma. In this study, an enriched TIC population was identified in two canine malignant melanoma cell lines (CML1 and CML6M) using cell surface markers and functional assays, including the sphere forming assay, aldehyde dehydrogenase (ALDH) assay, reverse ...
Cheng J X JX Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA. - - 2013
Cytogenetically normal myelodysplastic syndrome (CN-MDS) can pose diagnostic challenges and its pathogenetic mechanism remains elusive. By focusing on cytogenetically normal refractory cytopenia with multilineage dysplasia (CN-RCMD), a subtype of MDS, our genome-wide profiling showed ∼4600 annotated gene promoters with increased Histone H3 lysine 27 trimethylation (H3K27me3) in CN-RCMD, when compared ...
Leunig Michael M Department of Orthopaedic Surgery, Schulthess Clinic, Zurich, Switzerland. - - 2013
The direct anterior approach for THA allows implantation through an internervous plane without muscle detachment from bone. However, the classic longitudinal skin incision does not follow the anatomic skin creases and can result in scar widening. We therefore modified our incision technique to a short oblique skin incision following the ...
Yamana Ippei - - 2013
Purpose: Reconstruction with free jejunal graft (FJG) has been widely accepted for patients undergone pharyngo-cervical esophageal resection. Those patients often suffer variety of complications regarding postoperative peros function. We investigated risk factors especially focused on the development of dysphagia after FJG reconstruction. Methods: A retrospective analysis was conducted using clinical ...
Sy Charlotte - - 2013
Newly identified spore-forming pigmented marine bacteria, Bacillus indicus HU36 and Bacillus firmus GB1, are sources of carotenoids (mainly 15 yellow and orange pigments and 13 pink pigments, respectively) with original structures. These bacterial carotenoids were evaluated for their ability to inhibit the iron-induced peroxidation of linoleic acid micelles, or sunflower ...
Oesterle Sabrina - - 2013
Communities That Care (CTC) is a universal, science-based community prevention system designed to reduce risk, enhance protection, and prevent adolescent health and behavior problems community wide. CTC has been found to have sustained effects on cigarette use and delinquent and violent behaviors in grade 10 in a panel of 4,407 ...
Kim Sangjin - - 2013
Allostery is well documented for proteins but less recognized for DNA-protein interactions. Here, we report that specific binding of a protein on DNA is substantially stabilized or destabilized by another protein bound nearby. The ternary complex's free energy oscillates as a function of the separation between the two proteins with ...
Edds-Walton Peggy L - - 2013
Previous work on auditory processing in Opsanus tau has focused on the descending octaval nucleus; however, the magnocellular octaval nucleus receives similar inputs from the otolithic endorgans. The purpose of this study was to assess whether cells in any of the three subdivisions of the magnocellular nucleus respond to auditory ...
Sanchez-Macedo N N Laboratory for Applied Radiation Oncology, Department of Radiation Oncology, University Hospital, Zurich, - - 2013
Despite the prominent pro-apoptotic role of p53, this protein has also been shown to promote cell survival in response to metabolic stress. However, the specific mechanism by which p53 protects cells from metabolic stress-induced death is unknown. Earlier we reported that carnitine palmitoyltransferase 1C (CPT1C), a brain-specific member of a ...
Kimani Peter K - - 2013
Seamless phase II/III clinical trials combine traditional phases II and III into a single trial that is conducted in two stages, with stage 1 used to answer phase II objectives such as treatment selection and stage 2 used for the confirmatory analysis, which is a phase III objective. Although seamless ...
Xiao-Hong Li - - 2013
The solubility parameters of TNAD, HMX, RDX, DINA, DNP propellants were predicted by molecular dynamics (MD) simulation in order to evaluate the miscibility of TNAD and the other four propellants. The results show that the order of miscibility is TNAD/DINA > TNAD/DNP > TNAD/RDX > TNAD/HMX from the analysis of ...
Hagino Tetsuo - - 2013
PURPOSE: Hyponatremia in hospitalized patients has been reported to be associated with in-hospital mortality. We studied patients treated at our hospital for hip fracture regarding the factors related to hyponatremia at admission. METHODS: Among 580 patients aged 60 years or above who were admitted to our hospital since January 1997 for ...
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