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Hoffmann Thomas W - - 2013
ABSTRACT: Correction to Hoffmann et al., Virology Journal 2012 9:109.
Voigt Anja - - 2013
SCOPE: We aimed to evaluate the predictability of short-term (5 days) changes in epididymal white adipose tissue (eWAT) gene expression for long-term (12 weeks) changes induced by high-fat diet (HFD) feeding. METHODS AND RESULTS: Mice were fed semisynthetic diets containing 10 (low-fat diet) or 40 (HFD) energy% of fat. Global ...
Alhilli Mariam M - - 2013
Endometrial cancer (EC) is the most common malignancy of the female reproductive tract and the fourth most common cancer overall. Approximately 20 % of patients with EC harbor disease outside the uterus, and 10 % of patients initially diagnosed with cancer confined to the uterus are found to have lymph node metastases. ...
Spesso M F - - 2013
This study demonstrates the capacity of the one-step polymerase chain reaction (PCR) fingerprinting method using the microsatellite primers (GACA)(4) or (GTG)(5) (MSP-PCR) to identify six of the most frequent dermatophyte species causing cutaneous mycosis. PCR with (GACA)(4) was a suitable method to recognise Microsporum canis, Microsporum gypseum, Trichophyton rubrum and ...
Koutsounas Ioannis - - 2013
Pregnane X Receptor (PXR) is a member of the nuclear receptor superfamily, expressed in liver, intestine and other tissues. PXR exerts transcriptional regulation by binding to its DNA response elements as an heterodimer with Retinoid X Receptor (RXR). This nuclear receptor is implicated in the homeostasis of numerous endobiotics, such ...
Orive Miren - - 2013
PURPOSE: Limited data are available on the difficulties experienced over time by caregivers of patients with eating disorders (CPED). The aim of this study was to describe changes in anxiety and depression among such caregivers over 1 year and to identify factors predicting any change in both. METHODS: At recruitment, 145 ...
Deroy Ophelia - - 2013
A little over a decade ago, Martino and Marks (Current Directions in Psychological Science 10:61-65, 2001) put forward the influential claim that cases of intuitive matchings between stimuli in different sensory modalities should be considered as a weak form of synesthesia. Over the intervening years, many other researchers have agreed-at ...
Crestani Steben - - 2013
The inclusion of legumes in pasture reduces the need for mineral nitrogen applications and the pollution of groundwater; however, the agronomic and animal husbandry advantages with tropical legumes are still little known. The objective of this study was to quantify the effect of the use of forage peanut (Arachis pintoi ...
Crespel Amélie - - 2013
Investigating the nature of physiological traits potentially related to fitness is important towards a better understanding of how species and/or populations may respond to selective pressures imposed by contrasting environments. In northern species in particular, the ability to mobilize energy reserves to compensate for the low external energy intake during ...
van Kampen V - - 2013
Skin prick testing (SPT) in combination with the clinical history of the patient is one important step in the diagnosis of IgE-mediated occupational allergies. However, skin test performance is related to the quality of allergen extracts. The present consensus document was prepared by an EAACI Task Force consisting of an ...
Butenas Saulius - - 2013
Abstract Tissue factor (TF), an initiator of blood coagulation in vivo, is expressed in a variety of cells. Sufficient natural TF has been isolated to clone and express recombinant proteins ranging from full-length TF to its extracellular domain. Due to the limited availability of natural TF, recombinant proteins have been ...
Huang Lei - - 2013
Abstract Previous studies have demonstrated that Deuterohaemin-AlaHisThrValGluLys (DhHP-6), a novel porphyrin-peptide, increases lifespan and enhances stress resistance of Caenorhabditis elegans. To explore the possible mechanisms, in this study we investigated the roles of SIR-2.1 and DAF-16 in DhHP-6's function using wild type and various mutant strains of C. elegans. DhHP-6's ...
Takagi Dania - - 2013
Abstract Primary adrenal insufficiency, or Addison's disease, is very rare in the pediatric population. The diagnosis of Addison's disease is usually suspected in the presence of hyponatremia and hyperkalemia, or when adrenal crisis develops. Pediatricians often are unaware of other presenting symptoms of the disease. As a consequence, diagnosis is ...
Lam Sze Kwan - - 2013
A monomeric 9.4-kDa peptide with antifungal activity was isolated from seeds of Phaseolus vulgaris cv Legumi secchi by using a protocol that involved affinity chromatography on Blue-Sepharose, ion exchange chromatography on Q-Sepharose, and gel filtration on Superdex 75. It was adsorbed on Blue-Sepharose and unadsorbed on Q-Sepharose. Its N-terminal sequence ...
Takazaki Karen A G - - 2013
Autonomic dysfunction has been already described in patients with SCA3/MJD, but several important questions remain unanswered. The objectives of this study are to determine the frequency and the intensity of autonomic manifestations in SCA3/MJD, as well as to identify possible correlations between autonomic manifestations and genetic and clinical parameters. We ...
Yu Honghua - - 2013
Proliferative vitreoretinopathy (PVR), the most common cause of failure of rhegmatogenous retinal detachment (RD) surgery, is an anomalous scarring process related to ocular inflammation. Lysyl oxidase (LOX) is a copper-dependent amine oxidase that may play important roles in ocular tissue integrity. The aim of this study was to investigate whether ...
Swami Viren - - 2013
Previous studies of men's breast size preferences have yielded equivocal findings, with studies variously indicating a preference for small, medium, or large breasts. Here, we examined the impact of men's oppressive beliefs in shaping their female breast size ideals. British White men from the community in London, England (N = 361) viewed ...
Supronowicz Peter - - 2013
Multipotent adult progenitor cells (MAPCs) from bone marrow have been shown to be capable of forming bone, cartilage and other connective tissues. In addition, MAPCs differentiate into lineages that are different from their germ layers of origin. Previous studies showed the ability of MAPCs to improve cardiac function and control ...
Peng J - - 2013
Valosin-containing protein (VCP), or p97, is a member of the ATP-binding protein family, and is involved in numerous cellular events, such as, protein degradation, membrane fusion, and chaperone activity. VCP has been demonstrated playing a critical role in non-small-cell lung cancer (NSCLC) pathogenesis and progression recently. We investigated the association ...
Luo P P Environment Department, The University of York, Heslington, York, UK. - - 2013
Imaging and characterization of engineered nanoparticles (ENPs) in water, soils, sediment and food matrices is very important for research into the risks of ENPs to consumers and the environment. However, these analyses pose a significant challenge as most existing techniques require some form of sample manipulation prior to imaging and ...
Antenor-Dorsey Jo Ann V - - 2013
PURPOSE: N-([(11)C]Methyl)benperidol ([(11)C]NMB) can be used for PET measurements of D(2)-like dopamine receptor binding in vivo. We report the absorbed radiation dosimetry of i.v.-administered [(11)C]NMB, a critical step prior to applying this radioligand to imaging studies in humans. MATERIALS AND METHODS: Whole-body PET imaging with a CTI/Siemens ECAT 953B scanner ...
Berganzo Koldo - - 2013
Orthostatic hypotension and supine hypertension frequently coexist in Parkinson's disease (PD) patients, leading to visceral damage and increased mortality rates. The aim of this paper is to analyze the frequency and association of both conditions in a sample of outpatients with PD. A total of 111 patients, diagnosed with PD, ...
Sano Atsushi - - 2013
A 21-year-old man with a history of bronchial asthma during childhood presented with left recurrent pneumothorax. Chest x-ray showed collapse of the left lung. Computed tomography showed hyperlucency and some bullae in the left upper lobe. Thoracoscopic bullectomy and pleurodesis were performed. Pneumothorax recurred twice, for which thoracoscopic bullectomy and ...
White Helene R - - 2013
Personalized feedback interventions (PFIs) to reduce drinking in college students often provide feedback about negative alcohol-related consequences experienced by students to motivate them to drink less. Yet, there is evidence which suggests that not everyone perceives consequences as negative and raises questions regarding the utility of consequence-specific feedback for some ...
Djeghloul F - - 2013
Organic semiconductors constitute promising candidates toward large-scale electronic circuits that are entirely spintronics-driven. Toward this goal, tunneling magnetoresistance values above 300% at low temperature suggested the presence of highly spin-polarized device interfaces. However, such spinterfaces have not been observed directly, let alone at room temperature. Thanks to experiments and theory ...
Uesugi Haruka - - 2013
A series of heteroleptic platinum(ii) complexes ( and ) bearing a dicarbene ligand and a cyclometalated bidentate ligand have been prepared. Two of the complexes ( and ) were characterized by X-ray diffraction analyses, confirming the square-planar structures. Detailed spectroscopic properties of the complexes have been studied, and two complexes, ...
Siekmeyer Manuela - - 2013
Abstract The tricarboxylic acid (TCA) cycle represents the key enzymatic steps in cellular energy metabolism. Once the TCA cycle is impaired in case of inherited metabolic disorders, life-threatening episodes of metabolic decompensation and severe organ failure can arise. We present the case of a 6 ½-year-old girl with propionic acidaemia ...
Tian Rui - - 2013
Objective: The goals of this study were to establish a new model for predicting in-hospital mortality of percutaneous coronary intervention (PCI), and to compare the predictive accuracy of the new model with the European System for Cardiac Operative Risk Evaluation (EuroSCORE) model. Methods: We retrospectively analyzed 18206 Chinese patients undergoing ...
Yamane Shogo - - 2013
The introduction of bulky tert-butyl substituents into smectic liquid-crystalline 9,10-bis(phenylethynyl)anthracene derivatives influences excimer structures and luminescence properties.
Park Chan Hum - - 2013
Compelling evidence indicates that polyphenolic antioxidants show protective effects against diabetic complications. We investigated the effects of a polyphenolic compound, 7-O-galloyl- D-sedoheptulose (GS), from Corni Fructus on a type 2 diabetic db/db mouse model. After 6 weeks of GS treatment, the effects of GS on serum and pancreatic biochemical factors ...
Shingyoji Masato - - 2013
ABSTRACT: BACKGROUND: We have recently reported on the changes in plasma free amino acid (PFAA) profiles in lung cancer patients and the efficacy of a PFAA-based, multivariate discrimination index for the early detection of lung cancer. In this study, we aimed to verify the usefulness and robustness of PFAA profiling ...
Zieker Derek - - 2013
PURPOSE: Metastases are a frequent finding in gastric cancer and are associated with poor prognosis. A recently discovered link between metabolic changes, differentiation, and therapy resistance due to tumor stem cells could depict a novel approach in cancer research and therapy. Phosphoglycerate kinase 1 (PGK1) is a metabolic enzyme and ...
Vereckei András - - 2013
Abstract The authors report a case of rare chloroquine cardiotoxicity mimicking connective tissue disease heart involvement in a 56-year-old woman with mixed connective tissue disease (MCTD) manifested suddenly as third degree A-V block with QT(c) interval prolongation and short torsade de pointes runs ultimately degenerating into ventricular fibrillation. Immunological tests ...
Bergés-Tiznado Magdalena E - - 2013
In this study, we examined the bioavailability of arsenic through the mangrove oyster Crassostrea corteziensis sampled from seven coastal lagoons in SE Gulf of California during the rainy and dry seasons. As concentrations in soft tissue of oysters C. corteziensis fluctuated between 5.2 and 11.6 μg/g on dry weight; organisms from ...
Zhou Shuxia - - 2013
PURPOSE: Metal-catalyzed oxidation (MCO) of proteins is of primary concern in the development of biotherapeutics as it represents a prominent degradation pathway with potential undesired biological and biotherapeutic consequences. METHODS: We developed a fluorogenic derivatization methodology to study the MCO of IgG1 using a model oxidation system, CuCl(2)/L-ascorbic acid. RESULTS: ...
Zhu Lina - - 2013
Abstract Objective: In our study, the reference intervals of serum thyroid hormones were established in 247 hospitalized preterm infants from 28 to 36 weeks of gestation at 8-15 postnatal days. The thyroid hormones were serum triiodothyronine (T3), free triiodothyronine (FT3), thyroxine (T4), free thyroxine (FT4), and thyrotropin (TSH). Methods: Electrochemiluminescence ...
Müller Konrad - - 2013
Light is fundamental to life on earth. Therefore, nature has evolved a multitude of photoreceptors that sense light across all kingdoms. This natural resource provides synthetic biology with a vast pool of light-sensing components with distinct spectral properties that can be harnessed to engineer novel optogenetic tools. These devices enable ...
Chien Wai Tong - - 2013
OBJECTIVES This study tested the effectiveness of a mindfulness-based psychoeducation program for Chinese outpatients with schizophrenia over an 18-month follow-up. The program is a psychoeducational program that addresses patients' awareness and knowledge of schizophrenia and builds skills for illness management. METHODS A multisite controlled trial was conducted with 96 Chinese ...
Hyötyläinen Tuulia - - 2013
Lipids are a diverse class of metabolites that play several key roles in the maintenance of human health. Lipidomics, which focuses on the global study of molecular lipids in cells, tissues, and biofluids, has been advancing rapidly over the past decade. Recent developments in MS and computational methods enable the ...
Wang Jiang-Ping - - 2013
Morphological and functional studies have confirmed that interstitial cells of Cajal (ICCs) are involved in many enteric motor neurotransmission pathways. Recent investigations have demonstrated that human and guinea pig prostate glands possess a distinct cell type with morphological and immunological similarities to ICCs. These prostate ICCs have a close relationship ...
Fukuda Atsushi - - 2013
In Japan, the entrance air kerma rate (EAKR) to a patient cannot exceed 50 mGy/min in conventional fluoroscopy. However, it is unclear where the EAKR should be measured. We obtained the tube potential and tube current as a function of polymethylmethacrylate (PMMA) thickness, and the EAKR at the interventional reference point ...
Virtanen Kaisa J - - 2013
Long-term outcome after surgery for grade-V acromioclavicular joint dislocation has not been reported. We performed a retrospective analysis of functional and radiographic outcome 15-22 years after surgery. We examined 50 patients who were treated at our hospital between April 1985 and December 1993. Various methods of stabilization were used: K-wires ...
Rabiei Afsaneh - - 2013
Polyetheretherketone (PEEK) is a high-performance polymer with advantages over metallic biomaterials for application in spinal implants. In this study, hydroxyapatite (HA) coatings were deposited onto PEEK substrates using radio-frequency magnetron sputtering for the purpose of improving bioactivity. An intermediate coating layer of yttria-stabilized zirconia (YSZ) was first deposited onto the ...
Lee Sang-Woon - - 2013
The present study was undertaken to examine the effects of cisplatin plus 4-hexylresorcinol (4-HR) combination therapy on oral mucosal melanoma (OMM) using cultured primary OMM cells in a tumour xenograft model. Cultured primary OMM cells were used for the MTT assay and DNA microarray. OMM cells were implanted into the ...
Li Guo Liang - - 2013
Functional polymer micro- and nanoparticles with novel morphology are of great importance because of their wide range of applications in complex biological systems and nanotechnology. Due to the outstanding advantage of the absence of any surfactant, precipitation polymerization as a heterogeneous polymerization technique has been developed to prepare various uniform ...
Edelaar Pim - - 2013
Shoval et al. (Reports, 1 June 2012, p. 1157) showed how configurations of phenotypes may identify tasks that trade off with each other, using randomizations assuming independence of data points. I argue that this assumption may not be correct for most and possibly all examples and led to pseudoreplication and ...
Smith Gregory N - - 2013
Concentration dependent aggregation of two surfactants, anionic sodium dioctylsulfosuccinate (Aerosol OT or AOT) and nonionic pentaethylene glycol monododecyl ether (C12E5), has been studied in cyclohexane-D12 using small-angle neutron scattering (SANS). A clear monomer to aggregate transition has been observed for both surfactants, spherical inverse micelles for AOT and hank-like micelles ...
Im Gun-Il - - 2013
Changes occurring in the chondrocyte gene that control articular cartilage are important for the onset and progression of osteoarthritis (OA). However, actual development of the disease may be also controlled by changes in epigenome. Topics include the association of the three components of epigenetic modification, i.e., DNA methylation, histone modification, ...
Nguyen Kong Thong - - 2013
Protein methyltransferases (PMTs) are a novel gene family of therapeutic relevance involved in chromatin-mediated signaling and other biological mechanisms. Most PMTs are organized around the structurally conserved SET domain that catalyzes the methylation of a substrate lysine. A few potent chemical inhibitors compete with the protein substrate, and all are ...
Sezai Akira - - 2013
Purpose: Recently, coronary atrial bypass grafting (CABG) for dialysis patients increase, but the mortality is still high. Additionally, many patients show major adverse cardiovascular and cerebrovascular event (MACCE) after discharge and long-term results are not satisfactory. Methods: Ninety patients underwent CABG for dialysis patients. Logistic regression analysis was conducted using ...
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