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Results 301 - 350 of 3462
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Di Nardo W - - 2013
The purpose of this study was to evaluate the benefits of unilateral cochlear implant (CI) in patients over 60 on speech perception and quality of life, comparing the results obtained with a control group of younger CI recipients. Twenty CI users (mean age 72 years), postlingually deafened, were included in this ...
Sautner Judith - - 2013
Osteoarthritis (OA) is one of the most frequent indications in musculoskeletal imaging because OA is the most prevalent musculoskeletal disease in developed countries. As the population becomes older and older, the need for adequate imaging techniques also increases. The various forms of osteoarthritis are associated with a high degree of ...
Song Jiankang - - 2013
C6-carboxy-cellulose with a carboxylate content of 0.8 mmol g(-1) was obtained by oxidation of once-dried cellulose, using the 2,2,6,6-tetramethylpiperidinyl-1-oxyl (TEMPO)/NaClO/NaClO(2) system at pH 6.8 and 60 °C for 16 h. This method, with the addition of reagents in the order TEMPO, NaClO and NaClO(2), was 38 h faster than a ...
Surman Craig B H - - 2013
While symptoms of deficient emotional self-regulation (DESR) such as low frustration tolerance, temper outbursts, emotional impulsivity, and mood lability are commonly associated with attention deficit hyperactivity disorder (ADHD), little is known about their nature. The main aim of this post hoc study was to examine the correlates of DESR in ...
Raval Saurin - - 2013
The patent application WO2012082947 claims novel compounds as agonists of a plasma membrane-bound bile acid receptor TGR5. By activating TGR5, the agonists improve glycemic control and enhance energy expenditure. The basic generic claim of the patent covers pyrazole derivatives, different permutations on the core pyrazole ring are covered in the ...
Yamashita Yo-Ichi - - 2013
BACKGROUNDS: Pancreaticoduodenectomy (PD) is an aggressive surgery with considerable operative risks, but offers the only chance for cure in patients with periampullary tumors. A growing number of elderly patients are being offered PD because of the aging of populations in developed countries. We examined surgical outcomes of PD in patients ...
Lim Chetana - - 2013
BACKGROUND: Abdominal drainage is routinely performed after pancreaticoduodenectomy (PD), but this policy has recently been challenged. The aim of the present study was to assess whether abdominal drainage could be omitted after PD in patients at low risk of pancreatic fistula (PF). METHODS: From 2009 to 2011, 27 consecutive patients ...
Brodin T - - 2013
Environmental pollution by pharmaceuticals is increasingly recognized as a major threat to aquatic ecosystems worldwide. A variety of pharmaceuticals enter waterways by way of treated wastewater effluents and remain biochemically active in aquatic systems. Several ecotoxicological studies have been done, but generally, little is known about the ecological effects of ...
Cerquetella Matteo - - 2013
In the present work a retrospective study on vegetal foreign bodies (VFBs) localization inside the tracheobronchial tree of forty-one dogs is reported. Totally 47 grass awns were found, and only three dogs presented more than one FB. Most of VFBs were found inside right bronchial ramifications (76.6%, no. 36), while ...
Mexitalia Maria - - 2013
Abstract Aim: Uncoupling protein (UCP) genes, which may contribute to energy metabolism in mitochondria, may be involved in the pathogenesis of obesity. We analyzed the differences in energy expenditure between single nucleotide polymorphisms (SNPs) UCP3-55C/T, UCP3 Y210Y, and UCP2 A55V among Indonesian children. Methods: The study included 76 schoolchildren (36 ...
Simonsson Maria - - 2013
PURPOSE: Whether coffee modulates response to endocrine therapy in breast cancer patients is currently unknown. The CYP1A2 and CYP2C8 enzymes contribute to tamoxifen and caffeine metabolism. The purpose was to investigate the impact of coffee consumption on tumor characteristics and risk for early events in relation to breast cancer treatment ...
Chevalier Pierre - - 2013
Abstract Background and objectives The cost-effectiveness of pregabalin as an add-on to the standard treatment of Belgian patients with post-herpetic neuralgia (PHN) had been demonstrated in a previously published Markov model. The purpose of this study was to update that model with more recent cost data and clinical evidence, and ...
Wrzesien Maja - - 2013
Background: New technologies have slowly become a part of psychologists' therapeutic office. However, many therapists still have doubts about the possibility of creating a good therapeutic relationship with patients in the presence of technology. Aims: This study evaluates the development of the therapeutic alliance in individuals with small animal phobia ...
Schiwon Katarzyna - - 2013
The International Space Station (ISS) and the Antarctic Research Station Concordia are confined and isolated habitats in extreme and hostile environments. The human and habitat microflora can alter due to the special environmental conditions resulting in microbial contamination and health risk for the crew. In this study, 29 isolates from ...
Pfordresher Peter Q - - 2013
The vocal imitation of pitch by singing requires one to plan laryngeal movements on the basis of anticipated target pitch events. This process may rely on auditory imagery, which has been shown to activate motor planning areas. As such, we hypothesized that poor-pitch singing, although not typically associated with deficient ...
Kumar Ambuj - - 2013
Centrosomes are the key-regulating element of cell cycle progression. Aberrations in their functional mechanism lead to several cancer-related disorders. Aurora A protein is a centrosome-associated protein that regulates the centriole duplication and its abberations are associated with multiple cases of aneuploidy and cancer-related disorders. S155R mutation in Aurora A is ...
Cento Valeria - - 2013
A patient classified as HCV-1a positive by both LiPA Siemens 2.0 and Abbott RealTime HCV-Genotype II, was instead infected with HCV-1g, as determined by phylogenetic-analysis of NS3-sequences. HCV-1g NS3-sequences to date available naturally harbor the resistance-substitution T54S, plus P131S and L135F changes, located in the highly conserved NS3-positions within boceprevir-binding ...
Liu Bin - - 2013
A new hydrogen sensor was fabricated by coating a Pd-decorated In(2)O(3) film on Au electrodes. In response to 1 vol% H(2) at room temperature, an ultra high sensitivity of 4.6 × 10(7) was achieved. But after an annealing treatment in vacuum, its sensitivity degenerated by 4 orders of magnitude. In ...
Shetty Prakash - - 2013
Advances in agriculture and food systems, consequent increases in food availability, and a shift in dietary consumption patterns with economic development and urbanization of developing societies leads to adverse health outcomes. The structure of the habitual diet is altered and is characterized by increasing consumption of fats, saturated fats largely ...
Quesseveur G - - 2013
Evidence suggests that the serotonin 2A receptor (5-HT(2A)R) modulates the therapeutic activity of selective serotonin reuptake inhibitors (SSRIs). Indeed, among the genetic factors known to influence the individual response to antidepressants, the HTR2A gene has been associated with SSRIs response in depressed patients. However, in these pharmacogenetic studies, the consequences ...
Ivanova Anastasiya S - - 2013
Previous studies have shown that Agr genes, which encode thioredoxin domain-containing secreted proteins, play a critical role in limb regeneration in salamanders. To determine the evolutionary conservation of Agr function, it is important to examine whether Agrs play a similar role in species with a different type of regeneration. Here, ...
Butenas Saulius - - 2013
Abstract Tissue factor (TF), an initiator of blood coagulation in vivo, is expressed in a variety of cells. Sufficient natural TF has been isolated to clone and express recombinant proteins ranging from full-length TF to its extracellular domain. Due to the limited availability of natural TF, recombinant proteins have been ...
Huang Lei - - 2013
Abstract Previous studies have demonstrated that Deuterohaemin-AlaHisThrValGluLys (DhHP-6), a novel porphyrin-peptide, increases lifespan and enhances stress resistance of Caenorhabditis elegans. To explore the possible mechanisms, in this study we investigated the roles of SIR-2.1 and DAF-16 in DhHP-6's function using wild type and various mutant strains of C. elegans. DhHP-6's ...
Takagi Dania - - 2013
Abstract Primary adrenal insufficiency, or Addison's disease, is very rare in the pediatric population. The diagnosis of Addison's disease is usually suspected in the presence of hyponatremia and hyperkalemia, or when adrenal crisis develops. Pediatricians often are unaware of other presenting symptoms of the disease. As a consequence, diagnosis is ...
Lam Sze Kwan - - 2013
A monomeric 9.4-kDa peptide with antifungal activity was isolated from seeds of Phaseolus vulgaris cv Legumi secchi by using a protocol that involved affinity chromatography on Blue-Sepharose, ion exchange chromatography on Q-Sepharose, and gel filtration on Superdex 75. It was adsorbed on Blue-Sepharose and unadsorbed on Q-Sepharose. Its N-terminal sequence ...
Takazaki Karen A G - - 2013
Autonomic dysfunction has been already described in patients with SCA3/MJD, but several important questions remain unanswered. The objectives of this study are to determine the frequency and the intensity of autonomic manifestations in SCA3/MJD, as well as to identify possible correlations between autonomic manifestations and genetic and clinical parameters. We ...
Yu Honghua - - 2013
Proliferative vitreoretinopathy (PVR), the most common cause of failure of rhegmatogenous retinal detachment (RD) surgery, is an anomalous scarring process related to ocular inflammation. Lysyl oxidase (LOX) is a copper-dependent amine oxidase that may play important roles in ocular tissue integrity. The aim of this study was to investigate whether ...
Swami Viren - - 2013
Previous studies of men's breast size preferences have yielded equivocal findings, with studies variously indicating a preference for small, medium, or large breasts. Here, we examined the impact of men's oppressive beliefs in shaping their female breast size ideals. British White men from the community in London, England (N = 361) viewed ...
Supronowicz Peter - - 2013
Multipotent adult progenitor cells (MAPCs) from bone marrow have been shown to be capable of forming bone, cartilage and other connective tissues. In addition, MAPCs differentiate into lineages that are different from their germ layers of origin. Previous studies showed the ability of MAPCs to improve cardiac function and control ...
Peng J - - 2013
Valosin-containing protein (VCP), or p97, is a member of the ATP-binding protein family, and is involved in numerous cellular events, such as, protein degradation, membrane fusion, and chaperone activity. VCP has been demonstrated playing a critical role in non-small-cell lung cancer (NSCLC) pathogenesis and progression recently. We investigated the association ...
Edds-Walton Peggy L - - 2013
Previous work on auditory processing in Opsanus tau has focused on the descending octaval nucleus; however, the magnocellular octaval nucleus receives similar inputs from the otolithic endorgans. The purpose of this study was to assess whether cells in any of the three subdivisions of the magnocellular nucleus respond to auditory ...
Xiao-Hong Li - - 2013
The solubility parameters of TNAD, HMX, RDX, DINA, DNP propellants were predicted by molecular dynamics (MD) simulation in order to evaluate the miscibility of TNAD and the other four propellants. The results show that the order of miscibility is TNAD/DINA > TNAD/DNP > TNAD/RDX > TNAD/HMX from the analysis of ...
Hagino Tetsuo - - 2013
PURPOSE: Hyponatremia in hospitalized patients has been reported to be associated with in-hospital mortality. We studied patients treated at our hospital for hip fracture regarding the factors related to hyponatremia at admission. METHODS: Among 580 patients aged 60 years or above who were admitted to our hospital since January 1997 for ...
Milošković Aleksandra - - 2013
The concentrations of iron, lead, cadmium, copper, manganese, mercury and arsenic were measured in water, sediment, five macrophytes (Typha angustifolia, Iris pseudacorus, Polygonum amphybium, Myriophyllum spicatum and Lemna gibba) and five fish species (Sander lucioperca, Abramis brama, Carassius gibelio, Silurus glanis and Arystichtys nobilis) in the Gruža Reservoir, used for ...
Lilge Lothar - - 2013
Single cell transport in microfluidic devices is a topic of interest as their utility is becoming appreciated by cell and molecular biologist. Cell transport should minimize mechanical stress due to friction or pressure gradients. Optical forces have the advantage of applying their forces across the cell volume and not only ...
Kauffman L K - - 2013
Canine brucellosis is a reportable zoonotic disease that can lead to canine reproductive losses and human infection through contact with infected urine or other genitourinary secretions. Although many locations require testing and euthanasia of positive dogs, current diagnosis is limited by the time required for seroconversion, for example, presence of ...
da Silva Ferreira Thaís - - 2013
Recent studies have suggested that dietary Ca may have beneficial effects on adiposity, insulin resistance, dyslipidaemia and blood pressure (BP). One potential mechanism underlying these benefits involves modifications in intracellular Ca concentration ([Ca2+]i). The present study aimed to evaluate the associations of dietary Ca with adiposity, erythrocyte [Ca2+]i, metabolic profile, ...
Quiroz Lieschen H - - 2013
INTRODUCTION AND HYPOTHESIS: Our aim was to assess whether differences in the ages of nulliparous women affect: (1) interobserver reliability, and (2) visualization of the levator ani (LA) muscle subdivisions in nulliparous women using 3D endovaginal ultrasound (3D-EVUS). METHODS: This was a cross-sectional study. Community-dwelling nulliparous women ages 21-70 years ...
Mehlhorn Grit - - 2013
The benefits of cytology-based cervical cancer screening programs in reducing morbidity and mortality are well recognized. Especially, overtreatment of human papillomavirus (HPV) high-risk positive early dysplastic lesions may have a negative impact on reproductive outcomes for fertile women. To optimize the clinical management an objective standard is needed to distinguish ...
Schnell Ulrike - - 2013
The epithelial cell adhesion molecule (EpCAM; CD326) is highly expressed on epithelium-derived tumors and can play a role in cell proliferation. Recently, regulated intramembrane proteolysis (RIP) has been implicated as the trigger for EpCAM-mediated proliferative signaling. However, RIP does not explain all EpCAM-derived protein fragments. To shed light on how ...
Valent P - - 2013
Mast cell activation (MCA) occurs in a number of different clinical conditions, including IgE-dependent allergies, other inflammatory reactions, and mastocytosis. MCA-related symptoms may be mild, moderate, severe, or even life-threatening. The severity of MCA depends on a number of different factors, including genetic predisposition, the number and releasability of mast ...
Leta Samson - - 2013
The brown ear tick Rhipicephalus appendiculatus, vector of East Coast fever (ECF) and related cattle diseases caused by Theileria parva has never been reported from the Horn of Africa. Habitat suitability for this tick species was predicted using Maxent modelling technique based on R. appendiculatus records in Sub-Saharan Africa. Two ...
Lam King-Yeung - - 2013
We consider a two-species competition model in which the species have the same population dynamics but different dispersal strategies. Both species disperse by a combination of random diffusion and advection along environmental gradients, with the same random dispersal rates but different advection coefficients. Regarding these advection coefficients as movement strategies ...
Easton Scott D - - 2013
Men who were sexually abused during childhood represent a highly stigmatized, marginalized population at risk for a variety of long-term mental health problems. Using the family integration dimension of Durkheim's theory of suicide, factors associated with suicidal ideation among a purposive sample of 487 men with histories of child sexual ...
Heesch Sandra - - 2013
Acute leukemias of ambiguous lineage represent a heterogeneous group of rare, poorly characterized leukemias with adverse outcome. No larger studies have yet performed a combined approach of molecular and clinical characterization of acute undifferentiated leukemia (AUL) and biphenotypic acute leukemia (BAL) in adults. Here we describe 16 adults with AUL ...
Zhou Shuxia - - 2013
PURPOSE: Metal-catalyzed oxidation (MCO) of proteins is of primary concern in the development of biotherapeutics as it represents a prominent degradation pathway with potential undesired biological and biotherapeutic consequences. METHODS: We developed a fluorogenic derivatization methodology to study the MCO of IgG1 using a model oxidation system, CuCl(2)/L-ascorbic acid. RESULTS: ...
Zhu Lina - - 2013
Abstract Objective: In our study, the reference intervals of serum thyroid hormones were established in 247 hospitalized preterm infants from 28 to 36 weeks of gestation at 8-15 postnatal days. The thyroid hormones were serum triiodothyronine (T3), free triiodothyronine (FT3), thyroxine (T4), free thyroxine (FT4), and thyrotropin (TSH). Methods: Electrochemiluminescence ...
Müller Konrad - - 2013
Light is fundamental to life on earth. Therefore, nature has evolved a multitude of photoreceptors that sense light across all kingdoms. This natural resource provides synthetic biology with a vast pool of light-sensing components with distinct spectral properties that can be harnessed to engineer novel optogenetic tools. These devices enable ...
Chien Wai Tong - - 2013
OBJECTIVES This study tested the effectiveness of a mindfulness-based psychoeducation program for Chinese outpatients with schizophrenia over an 18-month follow-up. The program is a psychoeducational program that addresses patients' awareness and knowledge of schizophrenia and builds skills for illness management. METHODS A multisite controlled trial was conducted with 96 Chinese ...
Hyötyläinen Tuulia - - 2013
Lipids are a diverse class of metabolites that play several key roles in the maintenance of human health. Lipidomics, which focuses on the global study of molecular lipids in cells, tissues, and biofluids, has been advancing rapidly over the past decade. Recent developments in MS and computational methods enable the ...
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