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Results 251 - 300 of 3474
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Tennant Peter W G - - 2013
Studies of the association between early life infections and cancer have produced inconsistent findings, possibly due to limited adjustment for confounding and retrospective designs. This study utilised data from the Newcastle Thousand Families Study, a prospective cohort of 1,142 individuals born in Newcastle-upon-Tyne in 1947, to assess the impact of ...
Sasikala V - - 2013
BACKGROUND: Cataract, the leading cause of blindness, is associated with oxidative damage and protein modification in the lens. The present study was carried out to assess the efficacy of rutin on rat-lens crystallins in selenite-induced in-vivo cataract models. METHODS: Eight-day-old Sprague-Dawley rat pups were grouped as control (G I), experimental ...
Onesti Silvia - - 2013
The CMG (Cdc45-MCM-GINS) complex is the eukaryotic replicative helicase, the enzyme that unwinds double-stranded DNA at replication forks. All three components of the CMG complex are essential for its function, but only in the case of MCM, the molecular motor that harnesses the energy of ATP hydrolysis to catalyse strand ...
Haile Luke - - 2013
Session perceived exertion (S-RPE) and session affective responses (S-AR) are post-exercise estimates of the global responses experienced during exercise. To compare S-RPE and S-AR to acute RPE (A-RPE) and acute AR (A-AR) during self-selected (SS) and imposed (IMP) exercise of the same workload. Thirty-two males (22.3 ± 2.2 years) performed two, 20-min cycle ...
Gesteiro Eva - - 2013
Early alterations in glucose homeostasis increase the risk of developing insulin resistance and obesity later in life. The concurrence of altered lipids and insulin sensitivity/resistance markers at birth has been scarcely investigated. The study aimed to ascertain level ranges of homocysteine (tHcyt), arylesterase (AE), lipids/lipoproteins, and insulin resistance/sensitivity markers in ...
Caterino Marianna - - 2013
The biochemical phenotype of cells affected by ribosomal stress (RS) has not yet been studied in detail. Here we report a comparative proteomic analysis of shRPS19 TF-1 vs scramble TF-1 cells performed using the DIGE technology integrated to bioinformatics tools. Importantly, to achieve the broadest possible understanding of the outcome, ...
Crombie Felicity - - 2013
BACKGROUND: Molar incisor hypomineralisation (MIH) is a problematic condition with several characteristics for which infiltrant resins could theoretically improve clinical outcomes. AIM: To investigate whether caries infiltrant resin can penetrate MIH-affected enamel. DESIGN: Molar incisor hypomineralisation lesions (n = 21) were infiltrated using either the standard protocol or with the addition of ...
Wang Kun - - 2013
Periodic DFT method has been firstly used to calculate the bulk structure, electronic structure, electrical transferring and thermodynamic properties of crystalline 5-azido-1H-tetrazole (HCN(7)) and its four different salts. The anion CN(7) (-) was included in all of the salts such as ammonium 5-azidotetrazolate ([NH(4)](+)[CN(7)](-)), hydrazinium 5-azidotetrazolate ([N(2)H(5)](+)[CN(7)](-)), guanidinium 5-azidotetrazolate ([CH(6)N(3)](+)[CN(7)](-) · H(2)O) ...
Ueda Hitoshi - - 2013
We report a rare case of chronic expanding hematoma of thorax extended to the neck. An 83-year-old man with a history of Lucite ball plombage and thoracoplasty of bilateral thorax was admitted with numbness of left upper extremity. In 6 months, left supraclavicular fossa was gradually bulged like tumor. The ...
Knospe Melanie - - 2013
The rat adenine receptor (rAdeR) was the first member of a family of G protein-coupled receptors (GPCRs) activated by adenine and designated as P0-purine receptors. The present study aimed at gaining insights into structural aspects of ligand binding and function of the rAdeR. We exchanged amino acid residues predicted to ...
Alberding Brian G - - 2013
Evidence, based on femtosecond transient absorption and time resolved infrared spectroscopy, is presented for photoinduced charge transfer from the Mo(2)δ orbital of the quadruply bonded molecule trans-Mo(2)(T(i)PB)(2)(BTh)(2), where T(i)PB = 2,4,6-triisopropyl benzoate and BTh = 2,2'-bithienylcarboxylate, to di-n-octyl perylene diimide and di-n-hexylheptyl perylene diimide in thin films and solutions of ...
Liefooghe Baptist - - 2013
An increasing number of studies have demonstrated that a response in one task can be activated automatically on the basis merely of instructed stimulus-response (S-R) mappings belonging to another task. Such instruction-based response activations are considered to be evidence for the formation of S-R associations on the basis of the ...
Nickerson Jeffrey V - - 2013
Thinking often entails interacting with cognitive tools. In many cases, notably design, the predominant tool is the page. The page allows externalizing, organizing, and reorganizing thought. Yet, the page has its own properties that by expressing thought affect it: path, proximity, place, and permanence. The effects of these properties were ...
Lettau Michael - - 2013
INTRODUCTION: Our aim was to evaluate the in vitro visualization of different carotid artery stents on angiographic CT (ACT). Of particular interest was the influence of stent orientation to the angiography system by measurement of artificial lumen narrowing (ALN) caused by the stent material within the stented vessel segment to ...
Yang Dongjiang - - 2013
This feature article reviews some titanate-based adsorbents for the removal of radioactive wastes (cations and anions) from water. At the beginning, we discuss the development of the conventional ion-exchangeable titanate powders for the entrapment of radioactive cations, such as crystalline silicotitanate (CST), monosodium titanate (MST), peroxotitanate (PT). Then, we specially ...
Sukal-Moulton Theresa T Department of Physical Therapy and Human Movement Sciences, Northwestern University, 645 N Michigan Avenue Suite 1100, Chicago, IL 60611, - - 2013
This study investigated the presence of inter-limb activity at the elbow joint in individuals with childhood-onset hemiparesis, including spontaneous mirror movements during unilateral tasks and the ability to suppress them during bilateral tasks. Eighteen individuals with hemiparesis were divided into three categories of injury timing: before birth (PRE-natal), around the ...
Meyers Marc André - - 2013
Spider silk is extraordinarily strong, mollusk shells and bone are tough, and porcupine quills and feathers resist buckling. How are these notable properties achieved? The building blocks of the materials listed above are primarily minerals and biopolymers, mostly in combination; the first weak in tension and the second weak in ...
Bates Marsha E ME Center of Alcohol Studies, Rutgers, The State University of New Jersey, 607 Allison Road, Piscataway, NJ 08854-8001, USA. - - 2013
Neurocognitive impairments are prevalent in persons seeking treatment for alcohol use disorders (AUDs). These impairments and their physical, social, psychological and occupational consequences vary in severity across persons, much like those resulting from traumatic brain injury; however, due to their slower course of onset, alcohol-related cognitive impairments are often overlooked ...
Wahle Elmar - - 2013
Abstract Asymmetric dimethylation of arginine side chains in proteins is a frequent post-translational modification, catalyzed by type I protein arginine methyltransferases (PRMTs). This article summarizes what is known about this modification in the nuclear poly(A) binding protein (PABPN1). PABPN1 contains thirteen dimethylated arginine residues in its C-terminal domain. Three enzymes, ...
Geybels Milan S - - 2013
PURPOSE: Tea and coffee contain bioactive compounds and both beverages have recently been associated with a reduced risk of prostate cancer (PCa). METHODS: We studied associations of tea and coffee consumption with PCa risk in a population-based case-control study from King County, Washington, USA. Prostate cancer cases were diagnosed in ...
Flechl Birgit - - 2013
Glioblastoma multiforme (GBM) still harbors a fatal prognosis. The involvement of the neurocognition and psyche poses unique challenges for care provision by relatives. We lack data about the caregivers' perspective on the end-of-life (EOL) phase of GBM patients to improve counseling and support. In this study we investigated the experiences ...
Oh Byong Sun - - 2013
ABSTRACT: BACKGROUND: Accumulating evidence indicates that components of the systemic inflammatory response, such as C-reactive protein (CRP) and neutrophil-to-lymphocyte ratio (NLR), have been associated with prognosis of various cancers. We aimed to elucidate whether CRP and NLR could serve as potential surrogate markers for response and survival in patients with ...
Miyazaki Takuro - - 2013
A rare case of a patient with primary adenocarcinoma of the middle lobe bronchus that was successfully treated with rigid bronchoscopy followed by middle sleeve lobectomy is reported. The patient was a 75-year-old man who presented with low-grade fever and cough. Chest computed tomography showed obstructive pneumonia of the lower ...
Silva Sílvia A - - 2013
OBJECTIVES: The main goal of this study is to explore what is meant by "quality of care" (QoC) by both health professionals and patients. This research also intends to compare the perspectives of nurses, doctors and patients in order to understand whether these different actors share similar views on what ...
Ward-Ciesielski Erin F - - 2013
This open trial sought to develop and evaluate the preliminary feasibility and effectiveness of a brief, one-time, dialectical behavior therapy skills-based intervention with specific focus on ensuring acceptability to nontreatment-seekers. Treatment-seeking and nontreatment-seeking suicidal individuals were recruited successfully from the community. Both groups found the intervention valuable. Suicide ideation was ...
Piegari Elena E Department of Experimental Medicine, Section of Pharmacology, Second University of Naples, Naples, Italy. - - 2013
The increasing population of cancer survivors faces considerable morbidity and mortality due to late effects of the antineoplastic therapy. Cardiotoxicity is a major limiting factor of therapy with doxorubicin (DOXO), the most effective anthracycline, and is characterized by a dilated cardiomyopathy that can develop even years after treatment. Studies in ...
Skelton A A - - 2013
Density functional theory (DFT) calculations using the B3LYP and ωB97XD functionals and Møller-Plesset (MP2) calculations have been used to determine the energy of insertion of seven molecules (CO(2), N(2), O(2), CO, CH(4), He and H(2)O) into two sizes of polyhedral oligomeric silsesquioxane (POSS) cages, T(10) and T(12). Geometry optimization results ...
Chen Kelei - - 2013
Tissue engineering of a biological osteochondral multilayered construct with a cartilage-interface subchondral bone layer is a key challenge. This study presented a rabbit bone marrow stromal cell (BMSC)/silk fibroin scaffold-based co-culture approach to generate tissue-engineered osteochondral grafts with an interface. BMSC-seeded scaffolds were first cultured separately in osteogenic and chondrogenic ...
Galati Alexia - - 2013
We summarize findings from a study examining whether the availability of the conversational partner's spatial viewpoint influences the speaker's spatial memories, description strategies, their joint efficiency and accuracy on the task, as well as the partner's resulting spatial memories. In 18 pairs, Directors described to a misaligned Matcher arrays that ...
Santhosh M Sebastin - - 2013
Viper envenomations are characterized by prominent local and systemic manifestations including hematological alterations. Snake venom metalloproteinases (SVMPs) and phospholipase A(2) (PLA(2)) plays crucial role in the pathophysiology of hemorrhage by targeting/altering the platelets function which may result in thrombocytopenia. Platelets undergo the classic events of mitochondria-mediated apoptotic pathway due to ...
Leyva I - - 2013
The emergence of dynamical abrupt transitions in the macroscopic state of a system is currently a subject of the utmost interest. The occurrence of a first-order phase transition to synchronization of an ensemble of networked phase oscillators was reported, so far, for very particular network architectures. Here, we show how ...
Lefèvre Guillaume - - 2013
The mechanism of the formation of phenol from PhI and CsOH catalysed by copper(i) ligated to the 1,3-diketonate ket'(-) generated from 2,2,6,6-tetramethyl-3,5-heptanedione (TMHD) has been investigated by DFT calculations associated with experimental techniques: cyclic voltammetry, (1)H NMR, and ESI-MS. Weak halogen bonding between the negatively charged O atom of [(ket')Cu(I)-OH](-) ...
Li Guo Liang - - 2013
We report the development of silica/polymer double-walled hybrid nanotubes, which consist of a hollow cavity, a porous silica inner-wall and a stimuli-responsive (pH, temperature, and redox) polymeric outer-wall, as a novel nano-container system. The length, diameter, wall thickness and aspect ratio of the hybrid nanotubes are precisely controlled in the ...
Lv Jinglei - - 2013
The synthetically and biologically important 4-methyl and 4-methoxy tetrahydro-γ-carboline compounds were readily synthesized in high yields from an aryl amine and a 5-amino-3-oxopentanoate derivative through a series of reactions of enamination, oxidative annulation, deprotection/lactamization and the final reduction reaction of the carbonyl group. The underpinning strategy involves the oxidative C(sp(2))-C(sp(2)) ...
Kallala Rami - - 2013
Cigarette smoke has negative effects on bone metabolism and fracture repair. However, no study has reviewed effects of nicotine on bone and fracture repair independent of other constituents of cigarette smoke. The authors review the existing evidence of the effect of nicotine on 'bone' and 'bone cells' and fracture repair, ...
Li Ning - - 2013
OBJECTIVE Mental disability in China has become a significant public health problem. However, few studies have examined utilization of mental health services in China among people with mental disabilities. This study explored patterns of service use and associated socioeconomic factors among Chinese adults with mental disabilities. METHODS Data from a ...
Salama El-Sayed - - 2013
Two freshwater microalgae including Chlamydomonas mexicana and Scenedesmus obliquus were grown on Bold Basal Medium (BBM) with different levels of salinity up to 100 mM NaCl. The dry biomass and lipid content of microalgae were improved as the concentration of NaCl increased from 0 to 25 mM. Highest dry weight (0.8 and ...
Sovány Tamás T Department of Pharmaceutical Technology, University of Szeged, Eötvös u. 6., 6720 Szeged, - - 2013
The importance of in silico modeling in the pharmaceutical industry is continuously increasing. The aim of the present study was the development of a neural network model for prediction of the postcompressional properties of scored tablets based on the application of existing data sets from our previous studies. Some important ...
Harris Michael D MD Department of Orthopaedics, University of Utah, 590 Wakara Way, RM A100, Salt Lake City, UT 84108, - - 2013
An objective measurement technique to quantify 3D femoral head shape was developed and applied to normal subjects and patients with cam-type femoroacetabular impingement (FAI). 3D reconstructions were made from high-resolution CT images of 15 cam and 15 control femurs. Femoral heads were fit to ideal geometries consisting of rotational conchoids ...
Reiprich M - - 2013
BACKGROUND: One of the most promising strategies to face the increasing asthma prevalence and to prevent disease development might be an early contact with microbial compounds. However, little is known about an interaction between an early-life contact to microbial compounds leading to asthma protection in the offspring and a co-exposure ...
Simon D - - 2013
Extracellular DNA traps are part of the innate immune response and are seen with many infectious, allergic, and autoimmune diseases. They can be generated by several different leukocytes, including neutrophils, eosinophils, and monocytes, as well as mast cells. Here, we review the composition of these extracellular DNA-containing structures as well ...
Schmid Silvan - - 2013
Nanomechanical resonators have an unprecedented mass sensitivity sufficient to detect single molecules, viruses or nanoparticles. The challenge with nanomechanical mass sensors is the direction of nano-sized samples onto the resonator. In this work we present an efficient inertial sampling technique and gravimetric detection of airborne nanoparticles with a nanomechanical resonant ...
Swindle Jamala D JD Farquhar College of Arts and Sciences, Nova Southeastern University, Fort Lauderdale, FL, 33314, - - 2013
The discovery of a novel non-AT1, non-AT2 binding site for angiotensins in the rodent brain and testis that is unmasked by the organomercurial compound para-chloromercuribenzoic acid (PCMB) has catalyzed efforts to purify and characterize this protein. We recently reported that this protein is neurolysin and now report upon the specificity ...
Brown Paul - - 2013
This paper describes the synthesis and detailed characterization of a new set of magnetic surfactants containing lanthanide metal counterions. SQUID magnetometry has been used to elucidate the magnetic phase behaviour, and small-angle neutron scattering (SANS) provides evidence of micellar aggregation in aqueous media. This study also reveals that for cationic ...
Paterson Colin R - - 2013
Abstract We report 20 infants aged between 1 month and 6 months found to have subdural bleeding and also multiple unexplained fractures in a pattern similar to that described earlier as temporary brittle bone disease. Child abuse seemed unlikely as a cause of the fractures as in no case was ...
Crujeiras Ana B - - 2013
Abstract Diabetes mellitus and breast cancer are two important health problems. Type 2 diabetes and obesity are closely linked with both being associated with breast cancer. Despite abundant epidemiological data, there is no definitive evidence regarding the mechanisms responsible for this association. The proposed mechanisms by which diabetes affects breast ...
Ishihara Takayuki - - 2013
Background: Arterial repair in the early phase following implantation of a zotarolimus-eluting stent (ZES) remains unknown. Methods and Results: Following implantation of 49 Endeavor ZES in 33 patients, follow-up angioscopy was performed in 13 patients (26 ZES) in the early phase (EP; 123±24 days) and in 20 patients (23 ZES) in the ...
Kara Ibrahim - - 2013
Purpose: Short term results of on-pump and off-pump techniques in patients undergoing reoperative coronary artery bypass grafting (redo CABG) were investigated in this study. Methods: A total of 14.430 patients have undergone isolated coronary artery bypass grafting in our clinic from 1998 to 2010. Of these patients, 105 patients who ...
Cetinkaya Erdogan - - 2013
Background: There are many causes of mediastinal and hilar lymphadenopathy, such as neoplasms, granulomatous diseases, infections and reactive hyperplasia. Nowadays, the popularity of endobronchial ultrasound-guided transbronchial needle aspiration (EBUSTBNA) is increasing in the diagnosis of mediastinal and hilar lymphadenopathy. We aimed to investigate the diagnostic value of EBUS-TBNA in patients ...
Zhang Daijuan - - 2013
3,4-Dihydroxyacetophenone(3,4-DHAP) is one herbal extract from bald Mao-dong-qing leaves. We reported that 3,4-DHAP had anti-inflammatory function by decreasing tumor necrosis factor-α(TNF-α) secretion in macrophages. The aim of the study was to examine the effects of 3,4-DHAP on plasma and liver lipids, plasma alanine aminotranferase (ALT) and TNF-α level, vascular cell ...
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