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Yu Raymond - - 2013
BACKGROUND: The Paprosky acetabular defect classification is widely used but has not been appropriately validated. Reliability of the Paprosky system has not been evaluated in combination with standardized techniques of measurement and scoring. QUESTIONS/PURPOSES: This study evaluated the reliability, teachability, and validity of the Paprosky acetabular defect classification. METHODS: Preoperative ...
Ami Diletta - - 2013
ABSTRACT: The understanding of protein aggregation is a central issue in different fields of protein science, from the heterologous protein production in biotechnology to amyloid aggregation in several neurodegenerative and systemic diseases. To this goal, it became more and more evident the crucial relevance of studying protein aggregation in the ...
Lemon Greg - - 2013
A mathematical model, in the form of an integro-partial differential equation, is presented to describe the dynamics of cells being deposited, attaching and growing in the form of a monolayer across an adherent surface. The model takes into account that the cells suspended in the media used for the seeding ...
Kaplow Julie B - - 2013
Suicidal ideation substantially increases the odds of future suicide attempts, and suicide is the second leading cause of death among adolescents. A history of adverse life events has been linked with future suicidal ideation and attempts, although studies examining potential mediating variables have been scarce. One probable mediating mechanism is ...
Childs Andrew M - - 2013
A quantum walk is a time-homogeneous quantum-mechanical process on a graph defined by analogy to classical random walk. The quantum walker is a particle that moves from a given vertex to adjacent vertices in quantum superposition. We consider a generalization to interacting systems with more than one walker, such as ...
Pelagio-Flores Ramón - - 2013
The control of cell division by growth regulators is critical to proper shoot and root development. Alkamides belong to a class of small lipid amides involved in plant morphogenetic processes, from which N-isobutyl decanamide is one of the most active compounds identified. This work describes the isolation and characterization of ...
Virmani Jitendra - - 2013
Characterization of hepatocellular carcinomas (HCCs) and metastatic carcinomas (METs) from B-mode ultrasound presents a daunting challenge for radiologists due to their highly overlapping appearances. The differential diagnosis between HCCs and METs is often carried out by observing the texture of regions inside the lesion and the texture of background liver ...
Tan Louisa - - 2013
Background: Well-being in persons with dementia (PWD) depends much on the quality and type of care received. The Dementia Management Strategies Scale (DMSS) is a useful instrument to appraise care styles of caregivers. The present study expanded on previous research by refining and establishing the scale's content validity and psychometric ...
Wada Keiko - - 2013
Abstract Osteopetrosis is a rare genetic disorder characterized by increased bone mineral density (BMD) due to osteoclast failure. T-cell immune regulator 1 (TCIRG1) plays crucial roles on osteoclast function, and its mutation causes autosomal recessive osteopetorosis. However, mutations in TCIRG1 have never been identified in autosomal dominant osteopetrosis (ADO). A ...
Cho Eunae - - 2013
Iron is an essential nutrient for nitrogen-fixing legume root nodules, and the chelation of ferrous iron plays an important role in the mobility and availability of iron to the legume. In the present study, we investigated the iron-binding properties of low-molecular weight succinoglycans isolated from the nitrogen-fixing bacterium, Sinorhizobium meliloti. ...
van de Waterbeemd Bas - - 2013
At present only vaccines containing outer membrane vesicles (OMV) have successfully stopped Neisseria meningitidis serogroup B epidemics. These vaccines however require detergent-extraction to remove endotoxin, which changes immunogenicity and causes production difficulties. To investigate this in more detail, the protein content of detergent-extracted OMV is compared with two detergent-free alternatives. ...
Yoshida Yusaku - - 2013
PURPOSE: To report the 2-year results of reduced-fluence photodynamic therapy (RF-PDT) combined with intravitreal ranibizumab (IVR) for typical age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV). METHODS: Twenty-four previously untreated eyes of 23 AMD patients with decimal best-corrected visual acuity (BCVA) of less than 0.7 received the combined therapy, ...
Xu Shuai - - 2013
An exquisitely structured CPP consisting of a self-supported POM-Zn(ii) coordination polymer as the shell and a Fe(3)O(4) cluster as the core was synthesized, which could be fabricated as a supercapacitive film electrode showing prominent electrochemical activities for enormous energy storage.
Karpman D - - 2013
The endothelium lining the vascular lumen is continuously exposed to complement from the circulation. When erroneously activated on host cells, complement may generate a deleterious effect on the vascular wall leading to endothelial injury, exposure of the subendothelial matrix and platelet activation.In this review the contribution of complement activation to ...
Bhalla Vandana - - 2013
The binding behavior of nanoaggregates of pentacenequinone derivative having thiophene groups has been investigated toward various cations (Fe(3+), Fe(2+), Pd(2+), Mg(2+), Cd(2+), Hg(2+), Ni(2+), Zn(2+), Cu(2+), Pb(2+), Co(2+), K(+), Na(+) and Li(+)) using UV-vis and fluorescence spectroscopy. Among the various cations tested, nanoaggregates of compound show a selective and sensitive ...
Thompson Russell Edward - - 2013
Corneal disease is the fourth-leading cause of blindness. According to the World Health Organization, roughly 1.6 million people globally are blind as a result of this disease. The only current treatment for corneal opacity is a corneal tissue transplant. Unfortunately the demand for tissue exceeds supply, making a tissue engineered ...
Egan Sarah J - - 2013
Background: To date no research has investigated the link between Post Traumatic Stress Disorder (PTSD) and perfectionism in a clinical sample. Aims: The aim of the current study was to examine whether there is a relationship between PTSD and perfectionism. This is important to address as many studies have demonstrated ...
Throckmorton Amy L - - 2013
A blood pump specifically designed to augment flow from the great veins through the lungs would ameliorate the poor physiology of the failing univentricular circulation and result in a paradigm shift in the treatment strategy for Fontan patients. This study is the first to examine mechanical cavopulmonary assistance with a ...
Tsimachidis Constantinos - - 2013
Abstract The aim of this study was to examine the effect of a 10-week combined resistance/sprint training programme in the post-activation potentiation of sprint performance before, between and after resistance training sets. Twenty-six junior basketball players were randomly divided into a control and a combined training group. The combined training ...
Gasa Merce - - 2013
Hypoxic brain damage might explain persistent sleepiness in some continuous positive airway pressure-compliant obstructive sleep apnoea called residual excessive sleepiness. Although continuous positive airway pressure may not be fully efficient in treating this symptom, wake-promoting drug prescription in residual excessive sleepiness is no longer allowed by the European Medicines Agency. ...
Guo Huiling - - 2013
The corneal epithelial barrier dysfunction is associated with a number of disorders of the cornea. This study aims to investigate the role of integrin alpha v beta 6 (avb6) in maintaining the corneal epithelial barrier function. In this study, the association of avb6 and endosome/lysosome in the human corneal epithelial ...
Cui Bo - - 2013
Surface modifications of Au(111) electrode with 4-bromobenzenediazonium tetrafluoroborate (BBD) in acetonitrile (ACN) and 0.1 M HClO4 have been characterized by scanning tunneling microscopy (STM). In ACN, STM results reveal the formation of disordered thin organic films. The involvement of radical as intermediate is evidenced by the negative effect of radical ...
Akunne Anayo - - 2013
This article summarizes the detailed cost-effectiveness analysis of delirium prevention interventions in people undergoing surgical repair of hip fracture. We compared a multi-component delirium prevention intervention with usual care using a model based on a decision tree analysis. The model was used to estimate the incremental net monetary benefit (INMB). ...
Hauerslev S - - 2013
BACKGROUND AND OBJECTIVES: The aim of this study was to investigate whether inflammation and regeneration are prominent in mildly affected muscles of patients with facioscapulohumeral muscular dystrophy type 1A (FSHD1A). Inflammation in muscle has been suggested by MRI studies in patients with FSHD1A. METHODS: We analysed immunohistological and histological stains ...
Kyung Kim Yoon - - 2013
Bronchial artery aneurysms are rarely encountered, but they can cause life-threatening hemorrhages when they rupture. The authors report a case of a giant bronchial artery aneurysm with ultrashort neck in a 73-year-old woman who presented with massive hemoptysis. The aneurysm was successfully treated by a combination of transcatheter arterial embolization ...
Wu Tao - - 2013
Zebrafish is an invaluable vertebrate model in life science research and has been widely used in biological pathway analysis, molecular screening and disease modelling, among others. As a result, microscopic imaging has become an essential step in zebrafish phenotype analysis, and image segmentation thus plays an important role in the ...
Sinha Arun Kumar - - 2013
Phase pure spherical Sn-SnO(2) nanoparticles (∼50 nm) in gram level have been synthesized from well-defined SnO microplates (∼2.0 μm) using focused solar irradiation. The first step of the reaction involves simple stirring of a strong NaOH solution with fine SnCl(2)·2H(2)O powder. Precipitated blue black microplates of SnO are finally transformed ...
Petersen Johannes - - 2013
Hepatocellular carcinoma is one of the most common cause of cancer related death. The present review gives an overview on the loco-regional therapy performed by transarterial chemoembolization (TACE).TACE combines two different therapeutic approaches. First, application of chemotherapeutic agents into tumor's feeding vessels and second, selectively de-arterialization by different particle embolization ...
Benini Stefano - - 2013
Urease, the enzyme that catalyses the hydrolysis of urea, is a virulence factor for a large number of ureolytic bacterial human pathogens. The increasing resistance of these pathogens to common antibiotics as well as the need to control urease activity to improve the yield of soil nitrogen fertilization in agricultural ...
Jumper-Reeves Leslie - - 2013
The ever-increasing numbers of ethnic minority populations in the USA seeking social services suggest that a "multicultural paradigm shift" is underway and gaining speed. This shift will increasingly demand that prevention programs and interventions be more culturally responsive. Interventions that are not aligned with prospective participants' world views and experiences ...
Nagai Yohei - - 2013
PURPOSE: Sivelestat, a selective inhibitor of neutrophil elastase, has been reported to reduce acute lung injury associated with systemic inflammatory response syndrome. This study retrospectively investigated the effect of sivelestat on respiratory function in patients who underwent esophagectomy. METHODS: Patients who underwent esophagectomy for thoracic esophageal cancer between 2005 and ...
Wilson Andrew J - - 2013
Highly functionalised ruthenium(ii) tris-bipyridine receptor which acts as a selective sensor for equine cytochrome c (cyt c) is shown to destabilise the native protein conformation by around 25 °C. Receptors and do not exert this effect confirming the behaviour is a specific effect of molecular recognition between and cyt c, ...
Ohta Minoru - - 2013
To determine hemodynamic effects of hydroxyethyl starch (HES) infusion during anesthesia in horses, incremental doses of 6% HES were administered to 6 healthy Thoroughbred horses. Anesthesia was induced with xylazine, guaifenesin and thiopental and maintained with sevoflurane at 2.8% of end-tidal concentration in all horses. The horses were positioned in ...
Yüce A - - 2013
In this study, it was aimed to investigate the likelihood of detrimental effects of carbon tetrachloride (CCl(4) ) on male reproductive system through oxidative stress mechanism and also protective effects of cinnamon bark oil (CBO). For this purpose, 28 healthy male Wistar rats were divided into four groups, seven rats ...
Jeronimus B F - - 2013
BACKGROUND: High neuroticism is prospectively associated with psychopathology and physical health. However, within-subject changes in neuroticism due to life experiences (LEs) or state effects of current psychopathology are largely unexplored. In this 2-year follow-up study, four hypotheses were tested: (1) positive LEs (PLEs) decrease and negative LEs (NLEs) increase neuroticism; ...
Terashi Takerou - - 2013
PURPOSE: The objective of this study was to confirm the renal protective effect of remifentanil-based anesthesia in perioperative adult patients with chronic kidney disease (CKD). METHODS: A total of 90 non-dialysis perioperative adult patients with CKD, with preoperative estimated glomerular filtration rate from creatinine (eGFRcreat) values of lower than 50 ml/min/1.73 m(2), ...
Cardona Juan Felipe - - 2013
Recent studies suggest that action-verb processing is particularly affected in early stage Parkinson's disease (PD), highlighting the potential role of subcortical areas in language processing and in the semantic integration of actions. However, this disorder-related language impairment is frequently unrecognized by clinicians and often remains untreated. Early detection of action-language ...
Laborie Lene B - - 2013
BACKGROUND: Femoroacetabular impingement (FAI) is an incompletely understood clinical concept that implies pathomechanical changes in the hip as a cause for hip-related pain in young adults. While a positive anterior impingement test is suggestive of FAI, its association with clinical and radiographic findings remain unconfirmed in healthy young adults. QUESTIONS/PURPOSES: ...
Cipriani Paola - - 2013
INTRODUCTION: Vascular involvement is a key feature of Systemic sclerosis (SSc). Although the pericytes/endothelial cells (ECs) cross-talk regulates vessels formation, no evidences about the pericytes contribution to ineffective angiogenesis in SSc are available. Recent findings showed similarities between pericytes and Bone Marrow Mesenchymal Stem Cells (BM-MSCs). Due to difficulties in ...
Fathallah Salem - - 2013
This study assessed sediment pollution along the Tunisian coast using the sediment contact assay with embryo and larval life-stages of the clam Ruditapes decussatus. Sediment was collected from four sites for testing: Mahres, Monastir lagoon, Zarat and Chebba. Embryo development was significantly (p < 0.05) inhibited in sediment at concentrations ≥5 g L(-1) from ...
Morita Hideki - - 2013
Hereditary hemorrhagic telangiectasia (HHT; Osler-Weber-Rendu syndrome) is an uncommon disease characterized by abnormal telangiectasias and arteriovenous malformations that cause recurrent bleeding. Here, we present the case of a patient with HHT, who had a history of pulmonary and hepatic arteriovenous malformations and endocarditis of a prosthetic aortic valve that was ...
Kim Beom-Su - - 2013
Collagen sponges (COL-S) are used as scaffolds to support osteoblasts and stimulate bone repair because of their flexibility, biocompatibility, and biodegradability. In this study, we added fibrin networks to COL-S scaffolds by using a fibrinogen (FNG) cross-linking reaction and evaluated the proliferation, differentiation, and adhesion of MG-63 cells on these ...
Dhanani Akhilesh S - - 2013
The aim of the present study was to evaluate the potential of Lactobacillus plantarum CS24.2 to antagonize Escherichia coli adhesion and modulate the expression of inflammatory molecules by HT-29 cells response to the E. coli adhesion. This was carried out under different adhesion conditions and compared with the response seen ...
Liu Zhenzhen - - 2013
PURPOSE: Larotaxel is a new taxane compound with poor solubility. The aim of this study is to develop a new formulation to locate the poorly soluble drug and compare the pharmacokinetics and tissue distribution of larotaxel-loaded microsphere (LTX-LM) with the solution form larotaxel-solution (LTX-solution). METHODS: A sensitive and efficient UPLC-MS/MS ...
Switzer William - - 2013
Thalassemia is an inherited genetic disorder requiring multiple transfusions to treat anemia caused by low hemoglobin levels. Thus, thalassemia patients are at risk for infection with blood-borne pathogens, including human T-cell lymphotropic viruses (HTLV) that are transmitted by transfusion of cellular blood products. Here, we examined the prevalence of HTLV ...
Har R - - 2013
AIMS/HYPOTHESIS: High intraglomerular pressure causes renal inflammation in experimental models of diabetes. Our objective was to determine whether renal hyperfiltration, a surrogate for intraglomerular hypertension, is associated with increased excretion of urinary cytokines/chemokines in patients with type 1 diabetes mellitus. METHODS: Blood pressure, renal haemodynamic function (inulin and para-aminohippurate clearances ...
García-Medina J - - 2013
PURPOSE: To evaluate the value of duplex ultrasound assistance during thromboaspiration of thrombosed arteriovenous fistulae for haemodialysis. MATERIALS AND METHODS: We prospectively studied 54 thrombosed native fistulae (23 with total thrombosis and 31 with partial thrombosis), in which we performed manual thromboaspiration guided by ultrasonography associated with fluoroscopy. RESULTS: The ...
Gesteiro Eva - - 2013
Early alterations in glucose homeostasis increase the risk of developing insulin resistance and obesity later in life. The concurrence of altered lipids and insulin sensitivity/resistance markers at birth has been scarcely investigated. The study aimed to ascertain level ranges of homocysteine (tHcyt), arylesterase (AE), lipids/lipoproteins, and insulin resistance/sensitivity markers in ...
Caterino Marianna - - 2013
The biochemical phenotype of cells affected by ribosomal stress (RS) has not yet been studied in detail. Here we report a comparative proteomic analysis of shRPS19 TF-1 vs scramble TF-1 cells performed using the DIGE technology integrated to bioinformatics tools. Importantly, to achieve the broadest possible understanding of the outcome, ...
Crombie Felicity - - 2013
BACKGROUND: Molar incisor hypomineralisation (MIH) is a problematic condition with several characteristics for which infiltrant resins could theoretically improve clinical outcomes. AIM: To investigate whether caries infiltrant resin can penetrate MIH-affected enamel. DESIGN: Molar incisor hypomineralisation lesions (n = 21) were infiltrated using either the standard protocol or with the addition of ...
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