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Hong Eunsoo - - 2013
Microbial fermentation under anaerobic and microaerobic conditions has been used for the production of 1,3-propanediol (1,3-PD), a monomer used to produce polymers such as polytrimethylene terephthalate. In this study, we screened microorganisms using the high throughput screening method and isolated the Klebsiella pneumoniae AJ4 strain, which is able to produce ...
Howard Stephen A - - 2013
Within the adult population living with congenital heart defects, approximately 20 % have an atrial septal defect, which suggests that only 0.4-0.05 % of the entire adult population has an atrial septal defect (ASD). In patients with a left to right atrial shunt, treatments may include closure of the defect ...
van Elk Michiel - - 2013
Spatial perspective taking is a crucial social skill that underlies many of our everyday interactions. Previous studies have suggested that spatial perspective taking is an embodied process that involves the integration of both motor and proprioceptive information. Given the importance of vestibular signals for own-body perception, mental own-body imagery, and ...
Frank B - - 2013
OBJECTIVES: Paracetamol is frequently prescribed for pain and fever control in acute stroke patients, but its effect on stroke outcome is unclear. The aim was to investigate the safety and benefit of paracetamol administration in the acute phase of ischaemic stroke. METHODS: We analysed the impact of paracetamol exposure on ...
Sheikh Emran S - - 2013
Non healing wounds present a significant social and economic burden. Chronic non healing wounds are estimated to affect as many as 1-2% of individuals during their lifetime, and account for billions of dollars of expense annually on both a national and global basis. Our purpose is to describe the use ...
Surdutovich Eugene - - 2013
Radiation damage following the ionising radiation of tissue has different scenarios and mechanisms depending on the projectiles or radiation modality. We investigate the radiation damage effects due to shock waves produced by ions. We analyse the strength of the shock wave capable of directly producing DNA strand breaks and, depending ...
Veurink Marieke - - 2013
PURPOSE: To investigate the mechanism behind the aggregation breaking properties of dexamethasone phosphate and related corticosteroids on the IgG1 antibody bevacizumab (Avastin®). METHODS: An in silico 3D dimer model is developed to identify the bevacizumab-bevacizumab interface, and different corticosteroids are docked onto the model to distinguish preferred binding sites. In ...
Depetris Andrea Elizabeth - - 2013
OBJECTIVE Numerous articles have identified that medical technologies diffuse more rapidly among non-Latino whites compared with other racial-ethnic groups. However, whether health risk warnings also diffuse differentially across racial-ethnic minority groups is uncertain. This study assessed racial-ethnic variation in children's antidepressant use before and after the 2004 black-box warning concerning ...
Voigt Anja - - 2013
SCOPE: We aimed to evaluate the predictability of short-term (5 days) changes in epididymal white adipose tissue (eWAT) gene expression for long-term (12 weeks) changes induced by high-fat diet (HFD) feeding. METHODS AND RESULTS: Mice were fed semisynthetic diets containing 10 (low-fat diet) or 40 (HFD) energy% of fat. Global ...
Alhilli Mariam M - - 2013
Endometrial cancer (EC) is the most common malignancy of the female reproductive tract and the fourth most common cancer overall. Approximately 20 % of patients with EC harbor disease outside the uterus, and 10 % of patients initially diagnosed with cancer confined to the uterus are found to have lymph node metastases. ...
Spesso M F - - 2013
This study demonstrates the capacity of the one-step polymerase chain reaction (PCR) fingerprinting method using the microsatellite primers (GACA)(4) or (GTG)(5) (MSP-PCR) to identify six of the most frequent dermatophyte species causing cutaneous mycosis. PCR with (GACA)(4) was a suitable method to recognise Microsporum canis, Microsporum gypseum, Trichophyton rubrum and ...
Koutsounas Ioannis - - 2013
Pregnane X Receptor (PXR) is a member of the nuclear receptor superfamily, expressed in liver, intestine and other tissues. PXR exerts transcriptional regulation by binding to its DNA response elements as an heterodimer with Retinoid X Receptor (RXR). This nuclear receptor is implicated in the homeostasis of numerous endobiotics, such ...
Orive Miren - - 2013
PURPOSE: Limited data are available on the difficulties experienced over time by caregivers of patients with eating disorders (CPED). The aim of this study was to describe changes in anxiety and depression among such caregivers over 1 year and to identify factors predicting any change in both. METHODS: At recruitment, 145 ...
Deroy Ophelia - - 2013
A little over a decade ago, Martino and Marks (Current Directions in Psychological Science 10:61-65, 2001) put forward the influential claim that cases of intuitive matchings between stimuli in different sensory modalities should be considered as a weak form of synesthesia. Over the intervening years, many other researchers have agreed-at ...
Crespel Amélie - - 2013
Investigating the nature of physiological traits potentially related to fitness is important towards a better understanding of how species and/or populations may respond to selective pressures imposed by contrasting environments. In northern species in particular, the ability to mobilize energy reserves to compensate for the low external energy intake during ...
van Kampen V - - 2013
Skin prick testing (SPT) in combination with the clinical history of the patient is one important step in the diagnosis of IgE-mediated occupational allergies. However, skin test performance is related to the quality of allergen extracts. The present consensus document was prepared by an EAACI Task Force consisting of an ...
Djeghloul F - - 2013
Organic semiconductors constitute promising candidates toward large-scale electronic circuits that are entirely spintronics-driven. Toward this goal, tunneling magnetoresistance values above 300% at low temperature suggested the presence of highly spin-polarized device interfaces. However, such spinterfaces have not been observed directly, let alone at room temperature. Thanks to experiments and theory ...
Uesugi Haruka - - 2013
A series of heteroleptic platinum(ii) complexes ( and ) bearing a dicarbene ligand and a cyclometalated bidentate ligand have been prepared. Two of the complexes ( and ) were characterized by X-ray diffraction analyses, confirming the square-planar structures. Detailed spectroscopic properties of the complexes have been studied, and two complexes, ...
Siekmeyer Manuela - - 2013
Abstract The tricarboxylic acid (TCA) cycle represents the key enzymatic steps in cellular energy metabolism. Once the TCA cycle is impaired in case of inherited metabolic disorders, life-threatening episodes of metabolic decompensation and severe organ failure can arise. We present the case of a 6 ½-year-old girl with propionic acidaemia ...
Tian Rui - - 2013
Objective: The goals of this study were to establish a new model for predicting in-hospital mortality of percutaneous coronary intervention (PCI), and to compare the predictive accuracy of the new model with the European System for Cardiac Operative Risk Evaluation (EuroSCORE) model. Methods: We retrospectively analyzed 18206 Chinese patients undergoing ...
Yamane Shogo - - 2013
The introduction of bulky tert-butyl substituents into smectic liquid-crystalline 9,10-bis(phenylethynyl)anthracene derivatives influences excimer structures and luminescence properties.
Park Chan Hum - - 2013
Compelling evidence indicates that polyphenolic antioxidants show protective effects against diabetic complications. We investigated the effects of a polyphenolic compound, 7-O-galloyl- D-sedoheptulose (GS), from Corni Fructus on a type 2 diabetic db/db mouse model. After 6 weeks of GS treatment, the effects of GS on serum and pancreatic biochemical factors ...
Shingyoji Masato - - 2013
ABSTRACT: BACKGROUND: We have recently reported on the changes in plasma free amino acid (PFAA) profiles in lung cancer patients and the efficacy of a PFAA-based, multivariate discrimination index for the early detection of lung cancer. In this study, we aimed to verify the usefulness and robustness of PFAA profiling ...
Zieker Derek - - 2013
PURPOSE: Metastases are a frequent finding in gastric cancer and are associated with poor prognosis. A recently discovered link between metabolic changes, differentiation, and therapy resistance due to tumor stem cells could depict a novel approach in cancer research and therapy. Phosphoglycerate kinase 1 (PGK1) is a metabolic enzyme and ...
Vereckei András - - 2013
Abstract The authors report a case of rare chloroquine cardiotoxicity mimicking connective tissue disease heart involvement in a 56-year-old woman with mixed connective tissue disease (MCTD) manifested suddenly as third degree A-V block with QT(c) interval prolongation and short torsade de pointes runs ultimately degenerating into ventricular fibrillation. Immunological tests ...
Bergés-Tiznado Magdalena E - - 2013
In this study, we examined the bioavailability of arsenic through the mangrove oyster Crassostrea corteziensis sampled from seven coastal lagoons in SE Gulf of California during the rainy and dry seasons. As concentrations in soft tissue of oysters C. corteziensis fluctuated between 5.2 and 11.6 μg/g on dry weight; organisms from ...
Adikibi Boma T - - 2013
A 2-year-old female presented acutely with peritonitis and small bowel obstruction. An abdominal radiograph demonstrated a radiopaque foreign body. At laparotomy she was found to have bowel perforations with entero-enteric fistulae caused by four magnets. The magnets were removed, and debridement and closure of the perforations performed. We review our ...
Shankar Sreejith P - - 2013
Tubulysins are cytotoxic natural products with promising anti-cancer properties, originally isolated from myxobacterial cultures. Structurally, tubulysins are tetrapeptides, incorporating three unusual (Mep, Tuv and Tup) and one proteinogenic amino acid (Ile). Here we describe the synthesis and structure-activity relationship studies of novel tubulysin U and V analogues, with variations in ...
Kanagal-Shamanna Rashmi - - 2013
Aurora-A is a mitotic kinase implicated in oncogenesis and is known to be overexpressed in B-cell lymphomas and plasma cell myeloma. The expression of Aurora-A kinase (henceforth referred to as Aurora-A) in T-cell lymphomas is not well characterized. In this study, we assessed Aurora-A expression by immunohistochemical analysis in 100 ...
Delgado-Roche Livan - - 2013
Abstract Retained low-density lipoproteins (LDL) by arterial glycosaminoglycans (GAG) are more susceptible to reactive oxygen species-mediated oxidation, contributing to oxidative stress and atherosclerosis. Recently, we reported the properties of the chimeric mouse/human monoclonal antibody chP3R99-LALA to bind sulfated GAG, inhibit LDL-chondroitin sulfate binding and avoid LDL oxidation in vitro. Here, ...
Buijs Nikki - - 2013
Pharmaco-nutrients have beneficial effects on protective and immunological mechanisms in patients undergoing surgery, which are important for recovery after injury and in combating infectious agents. The aim of this review article was to outline the potential of the administration of nutritional substrates to surgical patients and the underlying mechanisms that ...
Birk D - - 2013
INTRODUCTION: The aim of this study was to demonstrate the safety and the efficacy of the self-gripping Parietex ProGrip™ mesh (Sofradim Production, Trévoux, France) used with the laparoscopic approach for inguinal hernia repair. The incidence of chronic pain, post-operative complications, patient satisfaction and hernia recurrence at follow-up after 12 months was ...
Zhang Aijun - - 2013
Using a ternary sex pheromone blend [86:6:6 v:v:v (Z,Z)-3,13-octadecadienyl acetate: (E,Z)-2,13-octadecadienyl acetate: (Z,E)-3,13-octadecadienyl acetate], we tested the effect of dispenser type and trap design for capture of dogwood borer (DWB), Synanthedon scitula Harris (Lepidoptera: Sesiidae) in apple orchards in West Virginia, Virginia, and North Carolina. Wing-style sticky traps baited with ...
Mairet Francis - - 2013
Under stress conditions, microalgae are known to accumulate large amounts of neutral lipids and carbohydrates, which can be used for biofuel production. However, on-line measurement of microalgal biochemical composition is a difficult task which makes the microalgal process rather difficult to manage. In this paper, we propose a so called ...
Tabolli Stefano - - 2013
BACKGROUND: Androgenic alopecia (AGA) is viewed as a relatively mild dermatologic condition; however, affected individuals feel that alopecia is a serious condition with major consequences in their life. OBJECTIVE: The objective of this study was to assess the health status, the risk of anxiety/depression, the coping strategies, and alexithymia in ...
Nagahama Masahiro - - 2013
Clostridium perfringens alpha-toxin (CP, 370 residues) is one of the main agents involved in the development of gas gangrene. In this study, the immunogenicity and protective efficacy of the C-terminal domain (CP251-370) of the toxin and phospholipase C (CB, 372 residues) of C. bifermentans, isolated from cases of clostridium necrosis, ...
Asada Tomohiko - - 2013
We observed a 59-year-old right-handed man with an infarction in his right-middle cerebral artery that included the parietal lobe, who abnormally manipulated mental images in the horizontal direction, resulting in calculation disturbances. Three years later, the patient suffered an infarction in the left parietal lobe and displayed abnormalities during the ...
Kato Takashi - - 2013
Bone marrow cell infusion (BMI) has recently been suggested as an effective therapy for refractory liver disease; however, the efficiency of BMI using canine bone marrow cells (cBMCs) has not been reported. We evaluated the accumulation potential of cBMCs in a mouse model of acute liver failure. Acute hepatitis was ...
Tyler Frances - - 2013
ABSTRACT: BACKGROUND: Post-mating interactions between the reproductive traits and gametes of mating individuals and among their genes within zygotes are invariably complex, providing multiple opportunities for reproduction to go awry. These interactions have the potential to act as barriers to gene flow between species, and may be important in the ...
Kaye Alan David - - 2013
Electrophysiological abnormalities of the QT interval of the standard electrocardiogram are not uncommon. Congenital long QT syndrome is due to mutations of several possible genes (genotype) that result in prolongation of the corrected QT interval (phenotype). Abnormalities of the QT interval can be acquired and are often drug-induced. Torsades de ...
Botteri Edoardo - - 2013
The impact of breast surgery on survival of metastatic breast cancer (MBC) patients is controversial. We addressed the question in a mono-institutional series of MBC patients with synchronous bone metastases. We identified 187 consecutive women diagnosed between 2000 and 2008 with locally operable (T1-T3) MBC, synchronous bone metastases, with no ...
Van Nguyen Huy - - 2013
Risks for HIV infection remain unknown in male street laborers. This research investigates patterns of self-reported risk behaviors among these men in urban Vietnam. In a cross-sectional survey using a social mapping technique, 450 men, mostly low-skilled and unregistered migrant laborers across 13 districts in Hanoi were approached for interviews. ...
Broadhouse Kathryn M - - 2013
Patent ductus arteriosus (PDA) remains common in preterm newborns, but uncertainty over optimal management is perpetuated by clinicians' inability to quantify its true haemodynamic impact. Our aim was to develop a technique to quantify ductal shunt volume and the effect of PDA on systemic blood flow volume in neonates. Phase ...
Cehreli Cavit - - 2013
Chronic basophilic leukemia (CBL) is an extremely rare disorder. A female patient presented with recurrent attacks of chills, fever and abdominal pain was found to have simultaneous cyclic oscillation in leukocyte counts and C-reactive protein values. She was initially diagnosed with familial Mediterranean fever and treated with colchicine. Diagnosis of ...
Skare Thelma L - - 2013
Recently, it has been found that some lupus patients may have anti-cyclic citrullinated peptide antibodies (anti-CCP), although the clinical significance of such finding is not well established. Systemic lupus erythematosus (SLE) patients may have joint complaints that are very similar to those observed in rheumatoid arthritis (RA). In early stages ...
Vermeulen Nicolas - - 2013
In the present experiments, participants had to verify properties of concepts but, depending on the trial condition, concept-property pairs were presented via headphones or on the screen. The results showed that participants took longer and were less accurate at verifying conceptual properties when the channel used to present the CONCEPT-property ...
Triantos Christos - - 2013
Chronic hepatitis C (CHC) and iron overload are the main causes of liver disease in β-thalassemia major (βTM). There is limited data regarding the course of CHC in this population. All patients (n = 144) from the thalassemia centre of the University Hospital of Patras were evaluated (January 1981 to June 2012). ...
Oneal M J - - 2013
Our laboratory has investigated replicating adenovirus-human sodium iodide symporter (Ad-hNIS) vectors in a combinatorial oncolytic approach known as radiovirotherapy. However, hNIS-mediated iodide sequestration requires an intact cell membrane, and the enhancement of infectivity may alter the radioiodide accumulation in vivo. To assess these effects, we constructed Ad-NIS vectors expressing NIS ...
Stawerska Renata - - 2013
Abstract Background: The E23K variant of the KCNJ11 gene is possibly responsible for changes in insulin secretion during the fetal life. We tried to assess the influence of the E23K variant on birth weight and metabolic profile in prepubertal children born small for gestational age (SGA). Subjects: One hundred and ...
Way Bruce B - - 2013
This study examined the prevalence, willingness to report, and treatment preferences for suicidal ideation among state prison inmates. The Beck Scale for Suicide Ideation (BSS) and a novel questionnaire were completed by 67 inmate-patients. The BSS score was in the high range for 15% of general population (GP) and 40% ...
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