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Sivasubramaniyan Kavitha - - 2013
Several strategies have been developed to facilitate the prospective isolation of Bone Marrow derived Mesenchymal Stem/Stromal Cells (BM-MSCs) based on the selective expression or absence of surface markers. Recently, we described the monoclonal antibodies W3D5 and W5C5, which selectively react with BM-MSCs but not with hematopoietic cells. Both antibodies showed ...
Belghiti Majedeline M Centro de Investigación Príncipe Felipe, 46012 Valencia, - - 2013
Persistent pruritus is a common disabling dermatologic symptom associated with different etiologic factors. These include primary skin conditions, as well as neuropathic, psychogenic, or systemic disorders like chronic liver disease. Defective clearance of potential pruritogenic substances that activate itch-specific neurons innervating the skin is thought to contribute to cholestatic pruritus. ...
Zhao Yanlin - - 2013
Several reports proposed that the extraordinary dominance of the SAR11 bacterial clade in ocean ecosystems could be a consequence of unusual mechanisms of resistance to bacteriophage infection, including 'cryptic escape' through reduced cell size and/or K-strategist defence specialism. Alternatively, the evolution of high surface-to-volume ratios coupled with minimal genomes containing ...
Teixeira Carla - - 2013
BACKGROUND: Ethical decision making in intensive care is a demanding task. The need to proceed to ethical decision is considered to be a stress factor that may lead to burnout. The aim of this study is to explore the ethical problems that may increase burnout levels among physicians and nurses ...
Caseiro Armando - - 2013
In the present study we applied iTRAQ-based quantitative approach to explore the salivary proteome and peptidome profile in selected subjects with type 1 diabetes, with and without micro-vascular complications, aiming to identify disease-related markers. From a total of 434 distinct proteins, bactericidal/permeability-increasing protein-like 1 and pancreatic adenocarcinoma up-regulated factor were ...
Lee Phyllis C PC School of Natural Sciences, University of Stirling, Stirling, UK. - - 2013
Growth from conception to reproductive onset in African elephants (Loxodonta africana) provides insights into phenotypic plasticity, individual adaptive plastic responses and facultative maternal investment. Using growth for 867 and life histories for 2652 elephants over 40 years, we demonstrate that maternal inexperience plus drought in early life result in reduced ...
Metts Brian S - - 2013
Bioaccumulation of contaminants and subsequent maternal transfer to offspring are important factors that affect the reproductive success of wildlife. However, maternal transfer of contaminants has rarely been investigated in amphibians. We examined maternal transfer of trace elements in southern toads (Bufo[Anaxyrus] terrestris) residing in two locations: 1) an active coal ...
Laser Benjamin S BS Department of Radiation Oncology, University of Maryland, Baltimore, Maryland, - - 2013
Fluorine-18 ((18)F) fluorodeoxyglucose (FDG) positron emission tomography (PET) is limited in its evaluation of brain tumors due to the high basal activity of the cerebral cortex and white matter. Carbon-11 methionine ((11)C MET) has little uptake under normal conditions. We prospectively investigated the uptake of (18)F FDG and (11)C MET ...
Carlson Stephen L SL Bowles Center for Alcohol Studies, University of North Carolina School of Medicine, Chapel Hill, NC 27599, - - 2013
Ethanol exposure produces alterations in GABAergic signaling that are associated with dependence and withdrawal. Previously, we demonstrated that ethanol-induced protein kinase C (PKC) γ signaling selectively contributes to changes in GABAA α1 synaptic receptor activity and surface expression. Here, we demonstrate that protein kinase A (PKA) exerts opposing effects on ...
Kandel Krishna Prasad - - 2013
Undoped and Mn(2+)-doped CdSe nanowires (NWs) grown by a solution-liquid-solid (SLS) method using Bi nanocatalysts have been studied by X-ray powder diffraction measurements. Except for heavily doped nanowires no measurable changes in nanowire lattice parameters were observed. The lattice parameter of heavily doped nanowires shrinks by about 0.5% compared with ...
Kadegowda A K G - - 2013
Palmitelaidic (C16:1 trans-9) acid has been suggested to have beneficial effects on human health including reduced adiposity. Objectives of this research were to: quantify the amounts of palmitelaidic acid in beef samples and determine the effect of palmitelaidic acid supplementation on lipogenesis in bovine preadipocytes and adipocytes in vitro. For ...
Chinen Takumi - - 2013
Glaziovianin A, an isoflavone isolated from the leaves of Ateleia glazioviana, inhibits the cell cycle progression in M-phase with an abnormal spindle structure, but its inhibitory mechanism has not been revealed. Here, we report that glaziovianin A and its derivatives are microtubule dynamics inhibitors. Glaziovianin A extended the time lag ...
Rampias T - - 2013
BackgroundWe sought to determine biomarker expression differences in head and neck squamous cell cancers (HNSCCs) based on p16/human papillomavirus (HPV) classification. In addition, our aim was to explore how expression of biomarkers is modulated after E6/E7 repression in HPV16(+) oropharyngeal cancer cells.MethodsHPV16(+) and HPV(-) HNSCC cells were infected with retroviruses ...
Newby Katie V - - 2013
ABSTRACT: BACKGROUND: The prevalence of unwanted pregnancy and sexually transmitted infection amongst young adults represents an important public health problem in the UK. Individuals' attitude towards the use of condoms has been identified as an important determinant of behavioural intentions and action. The Theory of Planned Behaviour has been widely ...
Assenza Gabriele Egidy - - 2013
OBJECTIVE: The Fontan operation is a staged palliation for complex congenital heart disease and single ventricle physiology. Perioperative survivors of the Fontan operation experience long-term cardiac complications, including death. Liver and renal dysfunction are reported in these patients and have a direct effect on morbidity and mortality. This study aims ...
Howard Sasha R - - 2013
Aim: To investigate the influence of growth hormone (GH) on linear growth before and during puberty in children with GH deficiency. Methods: We analysed the relationship between pubertal growth and GH dose in a large dataset of children (n = 236) with GH deficiency using multiple linear regression and multilevel ...
Suni J - - 2013
To develop an automatic system for utilizing electronic dental records, a data mining system to extract the diagnostic and treatment codes from the records for an intermediate file and automatic drawing of Kaplan-Meier-type survival curves was first created. Then this intermediate file was analyzed with SAS software for the scientific ...
Dinh Michael M - - 2013
INTRODUCTION: The aim of this study was to derive and internally validate a prediction rule for short stay admissions (SSAs) in trauma patients admitted to a major trauma centre. METHODS: A retrospective study of all trauma activation patients requiring inpatient admission at a single inner city major trauma centre in ...
Domkin Dmitry - - 2013
ABSTRACT The authors present a study of the relationship between individual variation in working memory capacity (WMC) and visually guided hand control in the face of visual distraction. WMC was assessed with the automated operation span task. Hand control was measured by requesting participants to track a visual target with ...
Moore Penny L PL Centre for HIV and STIs, National Institute for Communicable Diseases of the National Health Laboratory Services, Johannesburg, South Africa. - - 2013
Broadly cross-neutralizing (BCN) antibodies are likely to be critical for an effective HIV vaccine. However, the ontogeny of such antibodies and their relationship with autologous viral evolution is unclear. Here, we characterized viral evolution in CAP256, a subtype C-infected individual who developed potent BCN antibodies targeting positions R166 and K169 ...
Hu Jian-Yong - - 2013
The synthesis, crystal structures and photophysical properties of two types of pyrene-cored blue-light emitting [4]helicenes ( and ) are reported. The chemical structures of all synthesized compounds were fully confirmed by (1)H and (13)C NMR spectra, mass spectroscopy as well as elemental analysis. Single-crystal X-ray analysis of these [4]helicenes revealed ...
Shravage Bhupendra V BV Department of Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605, - - 2013
Atg6 (beclin 1 in mammals) is a core component of the Vps34 complex that is required for autophagy. Beclin 1 (Becn1) functions as a tumor suppressor, and Becn1(+/-) tumors in mice possess elevated cell stress and p62 levels, altered NF-κB signaling and genome instability. The tumor suppressor function of Becn1 ...
Su Jing - - 2013
Cisplatin resistance is a difficult problem in clinical chemotherapy, and the mechanisms involved in cisplatin resistance require further study. In this study, we investigated the role of chloride channel-3 (ClC-3) in cisplatin resistance. Autophagy was demonstrated by accumulation of LC3-II, beclin 1 and Atg12-Atg5. The ultrastructure changes were observed under ...
Rasouly Hila Milo HM Renal Section, Department of Medicine, Boston University Medical Center, Boston, MA, - - 2013
Congenital anomalies of the lower urinary tract (CALUT) are a family of birth defects of the ureter, the bladder, and the urethra. CALUT includes ureteral anomaliesc such as congenital abnormalities of the ureteropelvic junction (UPJ) and ureterovesical junction (UVJ), and birth defects of the bladder and the urethra such as ...
Gensicke Henrik - - 2013
OBJECTIVES: Data on long-term outcome after IV thrombolysis (IVT) are sparse. Our goals were to 1) estimate annual survival, and 2) evaluate determinants for an unfavorable long-term outcome after IVT for stroke. METHODS: This observational study is based on the IVT registry of the University Hospital Basel. A structured telephone ...
Chen Caiyou - - 2013
The first triphosphorus ligand has been designed and synthesized for highly regioselective linear hydroformylations. A very high l/b ratio (up to 471, 99.8% linear selectivity) was obtained in the linear hydroformylation of representative terminal and internal olefins. For the range of substrates tested, the regioselectivities achieved utilizing the novel triphosphoramidite ...
Baumgarten Werner - - 2013
The plasmodium of the slime mould Physarum polycephalum forms a transportation network of veins, in which protoplasm is transported due to peristaltic pumping. This network forms a planar, weighted, undirected graph that, for the first time, can be extracted automatically from photographs or movies. Thus, data from real transportation networks ...
Hafkenscheid Anton - - 2013
The 56-items Impact Message Inventory-Circumplex (IMI-C) has been developed to describe the interpersonal styles of target persons in terms of the 2-dimensional interpersonal circle, divided in 8 subscales (octants). The IMI-C is based on the assumption that a target person's interpersonal styles can validly be measured by assessing the internal ...
Petr Jan - - 2013
Arterial spin labeling (ASL) permits the noninvasive measurement of quantitative values of cerebral blood flow (CBF) and is thus well adapted to study inter- and intrasubject perfusion variations whether at rest or during an fMRI task. In this study, a template approach to detect brain activation as a CBF difference ...
Tsakiri Christina - - 2013
To investigate the implementation of home blood pressure monitoring (HBPM) guidelines, a phone survey was performed in 366 primary care physicians (PCPs). Of the PCPs, 90% routinely used HBPM for white-coat hypertension, treatment titration, and diagnosis. Thirty percent trusted HBPM more than office measurements. Reported drawbacks were questionable reliability of ...
Canet Jaume - - 2013
PURPOSE OF REVIEW: Postoperative pulmonary complications (PPCs) are common and lead to longer hospital stays and higher mortality. A wide range of patient, anaesthetic and surgical factors have been associated with risk for PPCs. This review discusses our present understanding of PPC risk factors that can be used to plan ...
Mastroianni Sarah E - - 2013
Nanostructured soft materials from self-assembled block copolymers (BCP)s and polymer blends can enable the reliable, high-throughput, and cost-effective generation of nanoscale structural motifs for many emerging technologies. Our research group has studied the phase behavior of BCPs in bulk, thin film, and solution environments with a particular focus on using ...
Bai Jinhe - - 2013
BACKGROUND: Fresh orange juice is perceived to be more wholesome than processed juice. Fresh juice may have nutrients and phytonutrients that differ from pasteurized or processed juice. RESULTS: 'Hamlin' and 'Valencia' oranges were extracted using a commercial food service juicer, pasteurized or not, resulting in fresh-commercial juice (FCJ) or pasteurized ...
Pareés Isabel - - 2013
Functional neurological symptoms are one of the most common conditions observed in neurological practice, but understanding of their underlying neurobiology is poor. Historic psychological models, based on the concept of conversion of emotional trauma into physical symptoms, have not been implemented neurobiologically, and are not generally supported by epidemiological studies. ...
Mimoto Futa F Research Division, Chugai Pharmaceutical Co., Ltd., Tokyo, - - 2013
Fc engineering is a promising approach to enhance the antitumor efficacy of monoclonal antibodies (mAbs) through antibody-dependent cell-mediated cytotoxicity (ADCC). Glyco- and protein-Fc engineering have been employed to enhance FcγR binding and ADCC activity of mAbs; the drawbacks of previous approaches lie in their binding affinity to both FcγRIIIa allotypes, ...
Hong Liu - - 2013
Detection of colorectal cancer at an early stage may significantly decrease mortality from the disease. The current screening test of colonoscopy is of high efficacy, but its acceptance in the general public is rather low. Availability of a blood- or stool-based test of DNA methylation markers is expected to improve ...
Liu Baiming - - 2013
For many insect-vectored plant viruses, the relationship between feeding behavior and vector competence may prove integral to an understanding of the epidemiology of the resulting plant disease. While plant-infecting viruses are well known to change host plant physiology in a way that makes them more attractive to vectors, viral manipulation ...
Montesdeoca-Santana Amada - - 2013
An analysis of the nucleation mechanism of pyramids formed in (100) silicon in Na2CO3/NaHCO3 solution has been carried out. This texturization process of silicon by means of Na2CO3/NaHCO3 solutions is of special interest because it can be applied to the silicon solar cell industry to texture solar cell surfaces to ...
Henaff Daniel - - 2013
Herpes simplex virus type 1 particles are multilayered structures with a DNA genome surrounded by a capsid, tegument, and envelope. While the protein content of mature virions is known, the sequence of addition of the tegument and the intracellular compartments where this occurs are intensely debated. To probe this process ...
Ota-Sullivan K K The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA. - - 2013
The impact of implementing the BinaxNow malaria test was evaluated. From 288 tests, 34 malaria cases were detected. Laboratory turnaround time decreased from 9.8 to 1.7 h for report of any Plasmodium spp., 10.2 to 1.6 h for P. falciparum, and 8.6 to 1.1 h for any result.
Luo Zhidan - - 2013
As a primary source of lycopene in the human diet, fleshy fruits synthesize this compound both de novo and via chlorophyll metabolism during ripening. SlSGR1 encodes a STAY-GREEN protein that plays a critical role in the regulation of chlorophyll degradation in tomato leaves and fruits. We report that SlSGR1 can regulate ...
Salama Afrah F - - 2013
Atherosclerosis is a condition caused by lipid build-up and inflammation in the arteries, so hyperlipidemia is the major reason for atherosclerosis. Testis was found to be negatively affected by hyperlipidemia which leads to its impaired functions. Vitamin E and <sc>l</sc>-carnitine have well-known lipid-lowering and antioxidative activities. Triton WR 1339 is ...
Chipman A A Centre for Comparative and Evolutionary Psychology, University of Portsmouth, Portsmouth, UK. - - 2013
Human mating and reproductive behaviour can vary depending on various mechanisms, including the local sex ratio. Previous research shows that as sex ratios become female-biased, women from economically deprived areas are less likely to delay reproductive opportunities to wait for a high-investing mate but instead begin their reproductive careers sooner. ...
Zimmermann Lars - - 2013
Palisade endings are nerve specializations found in the extraocular muscles (EOMs) of mammals, including primates. They have long been postulated to be proprioceptors. It was recently demonstrated that palisade endings are cholinergic and that in monkeys they originate from the EOM motor nuclei. Nevertheless, there is considerable difference of opinion ...
Favero Morgana - - 2013
During behavioral quiescence, the neocortex generates spontaneous slow oscillations, which may consist of up-states and down-states. Up-states are short epochs of persistent activity that resemble the activated neocortex during arousal and cognition. Neural activity in neocortical pathways can trigger up-states, but the variables that control their occurrence are poorly understood. ...
Miyahara Takuya T Division of Vascular and Endovascular Surgery, University of California-San Francisco, San Francisco, CA 94143-0222, - - 2013
Recent evidence suggests that specialized lipid mediators derived from polyunsaturated fatty acids control resolution of inflammation, but little is known about resolution pathways in vascular injury. We sought to determine the actions of D-series resolvin (RvD) on vascular smooth muscle cell (VSMC) phenotype and vascular injury. Human VSMCs were treated ...
Verma Sanjay - - 2013
Tropical pyomyositis (TP) is characterized by suppuration within skeletal muscles, manifesting as single or multiple abscesses. It has been reported frequently from Africa and Latin America. However, there are only a few cases reported in children from India. Between January 2002 and December 2011, 40 children with TP were admitted ...
Fimereli Danai - - 2013
High-throughput sequencing is becoming a popular research tool but carries with it considerable costs in terms of computation time, data storage and bandwidth. Meanwhile, some research applications focusing on individual genes or pathways do not necessitate processing of a full sequencing dataset. Thus, it is desirable to partition a large ...
Huyen Mai N T - - 2013
Background. In Vietnam, the Mycobacterium tuberculosis Beijing genotype is associated with (multi)drug resistance and is emerging. A possible explanation for this genotype's success is an increased rate of relapse.Methods. In a prospective cohort study, isolates from patients with smear-positive tuberculosis (TB) were subjected to drug susceptibility testing and spoligo and Variable Number ...
Johnson Christopher E - - 2013
Most narcotics-related cases in the United States involve Cannabis sativa. Material is typically identified based on the cystolithic hairs on the leaves and with chemical tests to identify of the presence of cannabinoids. Suspect seeds are germinated into a viable plant so that morphological and chemical tests can be conducted. ...
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