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Results 601 - 650 of 3309
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Li Q - - 2013
Objectives. Spontaneous intracerebral hemorrhage (ICH) is a challenge to both neurologists and neurosurgeons. We aim to summarize the surgical treatment of ICH based on retrospective analysis of our patients. Methods. Two hundred and fifty-three patients with spontaneous ICH from August 2008 to August 2011 were retrospectively analyzed. Clinical data, including ...
Chang Chen-Min - - 2013
In the post-human-genome-project era, the development of molecular diagnostic techniques has advanced the frontiers of biomedical research. Nucleic-acid-based technology (NAT) plays an especially important role in molecular diagnosis. However, most research and clinical protocols still rely on the manual analysis of individual samples by skilled technicians which is a time-consuming ...
Okita Yoshiki - - 2013
PURPOSE: To improve the selection of patients for percutaneous abscess drainage (PAD) to treat postoperative intra-abdominal abscess after gastrointestinal surgery, we investigated the factors predictive of outcome. METHODS: Of 143 consecutive patients with symptomatic postoperative intra-abdominal abscess after a gastrointestinal tract resection, 104 who underwent image-guided PAD as the initial ...
Bai Ru-Feng - - 2013
A block of an injury instrument will be left in wounds sometimes, and the suspect instrument can be discriminated by comparison with the block that was left through elemental analysis. In this study, three brands (Shibazi, Zhangxiaoquan, Qiaoxifu) of kitchen knives with forged, chop, and slice application series were analyzed ...
Kao Steven C - - 2013
PURPOSE: Malignant pleural mesothelioma (MPM) is considered a treatment-resistant disease. We determined the proportion of patients who received treatment in the last month of life and potential factors associated with use of chemotherapy at the end of life. METHODS: Consenting MPM patients compensated by the Dust Diseases Board (DDB) were ...
Kim Martha - - 2013
Purpose:  To investigate whether the amount of intraocular pressure (IOP) reduction with topical medications is associated with the progression of normal-tension glaucoma (NTG) and to identify risk factors for NTG progression. Methods:  The medical records of 121 eyes of 121 NTG patients, who were treated with topical medications for more ...
Pirkkalainen J-M - - 2013
Hybrid quantum systems with inherently distinct degrees of freedom have a key role in many physical phenomena. Well-known examples include cavity quantum electrodynamics, trapped ions, and electrons and phonons in the solid state. In those systems, strong coupling makes the constituents lose their individual character and form dressed states, which ...
Sun Li-Min - - 2013
OBJECTIVE: This study examines the possible association between urinary tract infection (UTI) and urinary tract cancer (UTC). MATERIALS AND METHODS: Data from the National Health Insurance (NHI) system of Taiwan were used for the analysis. The UTI cohort included 70116 patients whom were diagnosed and recruited in the whole country ...
Višnjar Tanja - - 2013
Optimizing culture conditions is known to be crucial for the differentiation of urothelial cell cultures and the formation of the permeability barrier. However, so far, no data exist to confirm if air-liquid (AL) and liquid-liquid (LL) interfaces are physiologically relevant during urothelial differentiation and barrier formation. To reveal the influence ...
Ruth Mr - - 2013
Objective: To develop an algorithm to identify and quantify BAT from PET/CT scans without radiologist interpretation. Design and Methods: Cases (n=17) were randomly selected from PET/CT scans with documented "brown fat" by the reviewing radiologist. Controls (n=18) had no documented "brown fat" and were matched with cases for age [51 ...
Wong Kwan-Yeung - - 2013
ABSTRACT: BACKGROUND: MIR129-2 has been shown to be a tumor suppressor microRNA hypermethylated in epithelial cancers.Patients and methods: Epigenetic inactivation of MIR129-2 was studied by methylation-specific PCR (MSP) in 13 cell lines (eight myeloma and five lymphoma), 15 normal controls and 344 primary samples including acute myeloid leukemia (AML), acute ...
Möckelmann N - - 2013
Metastasis and the associated loss of function of vital organs in the course of the disease is one of the main causes of death in head and neck cancer patients. An earlier and more reliable determination of metastasis and recurrence than currently obtained by common imaging methods could improve therapy ...
Schmidt Wiebke - - 2013
Human pharmaceuticals (e.g. the lipid regulator gemfibrozil and the non-steroidal anti-inflammatory drug diclofenac) are an emerging environmental threat in the aquatic environment. This study aimed to evaluate sublethal effects of these two commonly found pharmaceuticals on the protein profiles of marine mussels (Mytilus spp.). Mytilus spp. was exposed to environmentally ...
Sato Atsushi - - 2013
Synthetic C-reactive protein (CRP) rescues mice from lethal endotoxin shock or bacterial infection by suppressing tumor necrosis factor (TNF-α), but in turn, enhances Kupffer cell phagocytic activity. We herein assessed the influence of CRP in human peripheral blood mononuclear cells (PBMCs). When human PBMCs were stimulated in vitro with penicillin-treated ...
Morgan E E EE University of California, San Diego, San Diego, CA, USA. - - 2013
This is a cross-sectional, observational study to evaluate the hypothesis that HIV-seropositive (HIV+) apolipoprotein E4 (APOE4) carriers are at increased risk for HIV-associated neurocognitive disorders (HAND) compared to APOE4 noncarriers with HIV in the CNS HIV Antiretroviral Therapy Effects Research (CHARTER) Group sample. APOE genotype was determined in 466 CHARTER ...
Kallioniemi Hanna - - 2013
OBJECTIVE: We aimed to study vaginal fluid phosphorylated insulin-like growth factor binding protein-1 (phIGFBP-1) testing in early pregnancy to predict spontaneous preterm delivery (PTD). METHODS: Vaginal and cervical swab samples were collected from 5180 unselected women during the first-trimester (mean gestational age 13.1 weeks) ultrasound screening. PhIGFBP-1 was measured in vaginal ...
Milam A J - - 2013
Despite the national push encouraging children to walk to school, little work has been done to examine what hazards children encounter on the route to school. This study examined the association between the presence of alcohol outlets on children's route to school and perceived safety on the route to school ...
Salman Yazdi Reza - - 2013
Sperm motility is known as an effective parameter in male fertility, and it depends on energy consumption. Low-level laser irradiation could increase energy supply to the cell by producing adenosine triphosphate. The purpose of this study is to evaluate how the low-level laser irradiation affects the human sperm motility. Fresh ...
Chandrasekar T S - - 2013
Endoscopic obturation of gastric varices using tissue adhesive glues like cyanoacrylate is an accepted modality for the treatment of gastric varices. This study was undertaken to determine whether it was possible to predict immediate puncture site bleed on withdrawal of needle catheter during endoscopic glue injection without lipiodol. We prospectively ...
Aquilante Christina L CL Department of Pharmaceutical Sciences, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, 12850 East Montview Boulevard, Mail Stop C238, Aurora, CO 80045, USA. - - 2013
The objectives of this study were to determine if ABCB1 polymorphisms are associated with interindividual variability in sitagliptin pharmacokinetics and if atorvastatin alters the pharmacokinetic disposition of sitagliptin in healthy volunteers. In this open-label, randomized, two-phase crossover study, healthy volunteers were prospectively stratified according to ABCB1 1236/2677/3435 diplotype (n = ...
Urakami Hiromitsu - - 2013
Water-dispersible alkyne-bearing conjugated microporous poly-benzothiadiazoles were synthesized using thiol-yne chemistry to enhance water compatibility. The water compatible polymer networks were used as heterogeneous photocatalysts to generate singlet oxygen for the conversion of furoic acid to 5-hydroxy-2(5H)-furanone.
Manias Elizabeth - - 2013
BACKGROUND: Many patients with complex health-care needs are prescribed several medications on a daily basis. With admission to hospital, patients are often placed in a vulnerable position. Family members can therefore play an important role in supporting patients in decision making about managing medications and negotiating communication exchange with health ...
Li Xiaoyu - - 2013
A copper-catalysed oxidative C-H/N-H cross-coupling between formamides and amides through chelation-assisted N-H activation has been developed for the preparation of various multi-substituted ureas.
Ben-Shlomo Shani - - 2013
OBJECTIVES: Dipeptidyl peptidase 4 (DPP4) inhibitors, used in obese diabetic patients, reduce inflammation in several models. We investigated the role of chronic DPP4-deficiency (DPP4-) in diet-induced obesity with respect to insulin sensitivity and adipose tissue inflammation. DESIGN AND METHODS: Insulin resistance was induced by two months high fat diet (HFD). ...
Dudek A - - 2013
The aim of the study was to investigate the sensory innervation of the hip joint capsule in the rabbit. Individual animals were injected with retrograde fluorescent tracer Fast Blue (FB) into the lateral aspect of the left hip joint capsule (group LAT, n = 5) or into the medial aspect of the ...
Paulla Kirti K - - 2013
We study the electronic and magnetic structures of bilayer graphene nanoribbons (BGNRs) beyond the conventional AA and AB stackings, by using density functional theory within both local density and generalized gradient approximations (LDA and GGA). Our results show that, irrespective of the method chosen, stacking arrangements other than the conventional ...
Guyatt Gordon - - 2013
Dr. Cohen presents a passionate critique of the 9(th) edition of the American College of Chest Physician Guidelines on Antithrombotic Therapy (AT9), and in particular on its methodologist authors. We believe this attack is misguided and appreciate the opportunity to respond to Dr. Cohen. Dr. Cohen objects to the use ...
Osborne Kenneth L - - 2013
Amyloid protein aggregation characterizes many neurodegenerative disorders, including Alzheimer's, Parkinson's, and Creutzfeldt-Jakob disease. Evidence suggests that amyloid aggregates may share similar aggregation pathways, implying simulation of full-length amyloid proteins is not necessary for understanding amyloid formation. In this study we simulate GNNQQNY, the N-terminal prion-determining domain of the yeast protein ...
Monreal José A - - 2013
Salinity increases phosphoenolpyruvate carboxylase kinase (PEPCase-k) activity in sorghum leaves. This work has been focused on the mechanisms responsible for this phenomenon. The light-triggered expression of SbPPCK1 gene, accountable for the photosynthetic C(4)-PEPCase-k, is controlled by a complex signal transduction chain involving phospholipases C and D (PLC and PLD). These ...
Ryder Nuala - - 2013
This study focussed on young children's incorrect answers to pragmatically demanding questions. Children with specific language impairment (SLI), including a subgroup with pragmatic language difficulties (PLD) and typically developing children answered questions targeting implicatures, based on a storybook and short verbal scenarios. Ninety-seven children participated in this study: 30 children ...
Law-Ye Bruno - - 2013
BACKGROUND: Embolization of extra-axial tumors has shown its effectiveness in reducing perisurgical blood loss. However, the complication rate of this procedure is poorly reported. We aimed to evaluate the rate of procedure-related complications and their risk factors. METHODS: From 1998 to 2011, 193 consecutive patients (141 females, 52 males; mean ...
Luu Kenneth T KT Department of Clinical Pharmacology, Pfizer Global Research and Development, 10555 Science Center Drive, San Diego, CA 92121, USA. - - 2013
The industry-wide biopharmaceutical (i.e., biologic, biotherapeutic) pipeline has been growing at an astonishing rate over the last decade with the proportion of approved new biological entities to new chemical entities on the rise. As biopharmaceuticals appear to be growing in complexity in terms of their structure and mechanism of action, ...
Samuel-Hodge Carmen D - - 2013
OBJECTIVE: To translate a behavioral weight loss intervention for mid-life, low-income women in real world settings. DESIGN AND METHODS: In this pragmatic clinical trial, we randomly selected 6 North Carolina county health departments and trained their current staff to deliver a 16-session evidence-based behavioral weight loss intervention (special intervention, SI). ...
Watson Diane - - 2013
For those patients with CKD followed in a pre-dialysis environment, it is well appreciated that modality education leads to an informed decision regarding type of dialysis selected. However, for those individuals starting dialysis acutely and requiring chronic renal replacement therapy, modality education may be lacking. Because of the acuity of ...
Lee D S - - 2013
PURPOSE: To evaluate the treatment outcomes of low-dose whole brain radiation therapy (WBRT)-based differential radiation therapy (RT) for metastatic brain tumors. METHODS: A total of 242 targets (metastatic brain lesions) were analyzed in the present study. Median WBRT dose and number of fractions were 25 (range 25-35) Gy and 10 ...
Kuznetsova Olga M - - 2013
Proschan, Brittain, and Kammerman made a very interesting observation that for some examples of the unequal allocation minimization, the mean of the unconditional randomization distribution is shifted away from 0. Kuznetsova and Tymofyeyev linked this phenomenon to the variations in the allocation ratio from allocation to allocation in the examples ...
Zhaojun Wang - - 2013
In order to investigate the effect of manganese (Mn) deficiency on bone metabolism in chicks, ninety 1-day-old male Arbor Acre chicks were randomly divided into 3 groups and each group were given a diet having a different concentration of Mn (60 mg kg(-1), control group; 40 mg kg(-1), Mn-deficient group I; 8.7 mg kg(-1), Mn-deficient group ...
Spiezia Luca - - 2013
BACKGROUND: Activation of the clotting cascade is central in acute xenograft rejection (AHXR) that occurs when pig organs are transplanted into primates. The coagulopathy reported in this model is a very complex process that involves simultaneously coagulation factors, platelets and phospholipid-bearing cells (i.e., leukocytes, red blood cells, and endothelial cells). ...
Freak-Poli Rosanne - - 2013
OBJECTIVE: To evaluate whether participation in a four-month, pedometer-based, physical activity, workplace health program is associated with long-term sustained improvements in risk factors for type 2 diabetes and cardiovascular disease, eight-months after the completion of the program. DESIGN AND METHODS: A sample size of 720 was required. 762 Australian adults ...
Ducatez S - - 2013
Behavioural innovations have been largely documented in birds and are thought to provide advantages in changing environments. However, the mechanisms by which behavioural innovations spread remain poorly known. Two major mechanisms are supposed to play a fundamental role: innovation diffusion by social learning and independent appearance of the same innovation ...
Sanders Kathryn A KA VA Connecticut Healthcare System, West Haven, Connecticut, USA. - - 2013
Successful management of chronic kidney disease (CKD) typically involves consideration of several lifestyle changes and treatments that could improve patients' health outcomes. The complexity of behavioral changes and treatment decisions that must be made by patients, with the support of their treatment team, could diminish their motivation to address CKD ...
Chen Dianjun - - 2013
The non-self-quenched property of Frustrated Lewis Pairs (FLPs) contradicts the classical Lewis acid-base theory, but this peculiarity offers unprecedented possibilities for the activation of small molecules. Among all of their fascinating applications, FLP mediated hydrogen activation and the associated catalytic hydrogenations are currently considered as the most intriguing illustration of ...
Zhang Hongwen - - 2013
We report on a layer-controlled fabrication of two-dimensional (2D) WO(3) ordered nanoporous films via a step-by-step template-assisted strategy. For this purpose, a polystyrene sphere monolayer colloidal crystal (MCC), capable of intact transfer, is adopted as the fabrication template. WO(3) nanoporous films with a monolayer (L1), bilayer (L2) and trilayer (L3) ...
Joseph Elizabeth K EK Department of Medicine, Division of Neuroscience, University of California at San Francisco, San Francisco, California 94143-0440, - - 2013
Endothelin-1 (ET-1) is unique among a broad range of hyperalgesic agents in that it induces hyperalgesia in rats that is markedly enhanced by repeated mechanical stimulation at the site of administration. Antagonists to the ET-1 receptors, ET(A) and ET(B), attenuated both initial as well as stimulation-induced enhancement of hyperalgesia (SIEH) ...
Zhang Jingji - - 2013
The mammalian main olfactory pathway detects volatile chemicals using two families of G-protein-coupled receptors: a large repertoire of canonical odorant receptors and a much smaller set of trace amine-associated receptors (TAARs). The TAARs are evolutionarily conserved in vertebrates, including humans, suggesting an indispensible role in olfaction. However, little is known ...
Kalidasan Kamaladasan - - 2013
Gold nanoparticles (AuNPs) are well recognized tools for visual DNA detection. Most reports on their use have however been restricted to synthetic or PCR amplified DNA sequences. Herein, we describe a visual DNA detection method that can detect unamplified genomic DNA sequences specifically, using simple reagents and AuNPs, without the ...
Lai Wei W Department of Chemistry, The College of William & Mary, Williamsburg, Virginia 23187, United - - 2013
In the presence of Cd(ClO4)2 and a base, a new mixed N,S-donor alkylthiolate ligand supported both carbonate formation from atmospheric CO2 and the self-assembly of a novel bicapped puckered (CdS)6 molecular wheel. The remarkable stability of the complex was demonstrated by slow intermolecular ligand exchange on the (2)J(HH) and J((111/113)Cd(1)H) ...
von Lojewski Astrid - - 2013
Background: There is persuasive evidence for a relationship between eating disorders (EDs) and personality disorders (PDs). Research studies over the last three decades have used various tools to explore PDs in EDs with differing results. We investigated PDs derived from an interview - the International Personality Disorder Examination. Methods: 132 ...
Gross Elad - - 2013
Research to develop highly versatile, chiral, heterogeneous catalysts for asymmetric organic transformations, without quenching the catalytic reactivity, has met with limited success. While chiral supramolecular structures, connected by weak bonds, are highly active for homogeneous asymmetric catalysis, their application in heterogeneous catalysis is rare. In this work, the catalyst was ...
Mahabaleshwarkar Rohan - - 2013
Abstract Conflicting information currently exists about the role played by health-related quality of life (HRQOL) in influencing colorectal cancer screening. The current study aimed to determine the relationship between HRQOL and colorectal cancer screening, using nationally representative public data from the Behavioral Risk Factor Surveillance System (BRFSS). The 2010 BRFSS ...
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