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Sun Li-Min - - 2013
OBJECTIVE: This study examines the possible association between urinary tract infection (UTI) and urinary tract cancer (UTC). MATERIALS AND METHODS: Data from the National Health Insurance (NHI) system of Taiwan were used for the analysis. The UTI cohort included 70116 patients whom were diagnosed and recruited in the whole country ...
Višnjar Tanja - - 2013
Optimizing culture conditions is known to be crucial for the differentiation of urothelial cell cultures and the formation of the permeability barrier. However, so far, no data exist to confirm if air-liquid (AL) and liquid-liquid (LL) interfaces are physiologically relevant during urothelial differentiation and barrier formation. To reveal the influence ...
Ruth Mr - - 2013
Objective: To develop an algorithm to identify and quantify BAT from PET/CT scans without radiologist interpretation. Design and Methods: Cases (n=17) were randomly selected from PET/CT scans with documented "brown fat" by the reviewing radiologist. Controls (n=18) had no documented "brown fat" and were matched with cases for age [51 ...
Wong Kwan-Yeung - - 2013
ABSTRACT: BACKGROUND: MIR129-2 has been shown to be a tumor suppressor microRNA hypermethylated in epithelial cancers.Patients and methods: Epigenetic inactivation of MIR129-2 was studied by methylation-specific PCR (MSP) in 13 cell lines (eight myeloma and five lymphoma), 15 normal controls and 344 primary samples including acute myeloid leukemia (AML), acute ...
Möckelmann N - - 2013
Metastasis and the associated loss of function of vital organs in the course of the disease is one of the main causes of death in head and neck cancer patients. An earlier and more reliable determination of metastasis and recurrence than currently obtained by common imaging methods could improve therapy ...
Schmidt Wiebke - - 2013
Human pharmaceuticals (e.g. the lipid regulator gemfibrozil and the non-steroidal anti-inflammatory drug diclofenac) are an emerging environmental threat in the aquatic environment. This study aimed to evaluate sublethal effects of these two commonly found pharmaceuticals on the protein profiles of marine mussels (Mytilus spp.). Mytilus spp. was exposed to environmentally ...
Kallioniemi Hanna - - 2013
OBJECTIVE: We aimed to study vaginal fluid phosphorylated insulin-like growth factor binding protein-1 (phIGFBP-1) testing in early pregnancy to predict spontaneous preterm delivery (PTD). METHODS: Vaginal and cervical swab samples were collected from 5180 unselected women during the first-trimester (mean gestational age 13.1 weeks) ultrasound screening. PhIGFBP-1 was measured in vaginal ...
Milam A J - - 2013
Despite the national push encouraging children to walk to school, little work has been done to examine what hazards children encounter on the route to school. This study examined the association between the presence of alcohol outlets on children's route to school and perceived safety on the route to school ...
Salman Yazdi Reza - - 2013
Sperm motility is known as an effective parameter in male fertility, and it depends on energy consumption. Low-level laser irradiation could increase energy supply to the cell by producing adenosine triphosphate. The purpose of this study is to evaluate how the low-level laser irradiation affects the human sperm motility. Fresh ...
Chandrasekar T S - - 2013
Endoscopic obturation of gastric varices using tissue adhesive glues like cyanoacrylate is an accepted modality for the treatment of gastric varices. This study was undertaken to determine whether it was possible to predict immediate puncture site bleed on withdrawal of needle catheter during endoscopic glue injection without lipiodol. We prospectively ...
Kim Sang Jeong - - 2013
Cerebellar long-term depression (LTD) is induced by repetitive pairing of both synaptic inputs provided by climbing fibers (CFs) and parallel fibers (PFs), especially when CF stimulation followed by burst of PFs. Metabotropic glutamate receptor type 1 (mGluR1)-dependent signaling in Purkinje cells is critically involved in the induction of cerebellar LTD. ...
Stalder Jean-Francois - - 2013
Therapeutic patient education (TPE) has proven effective in increasing treatment adherence and improving quality of life (QoL) for patients with numerous chronic diseases, especially atopic dermatitis (AD). This study was undertaken to identify worldwide TPE experiences in AD treatment. Experts from 23 hospitals, located in 11 countries, responded to a ...
Izvekova Galina I - - 2013
The activities of major digestive hydrolases (proteases, amylase, lipase and esterases) along the intestine were studied in the burbot Lota lota (L.) using different methods of activity expression. The enzyme activities were determined both in the whole gut segments and in the isolated mucosa, and then expressed in terms of ...
Zamolo Valeria Anna - - 2013
Carbon nanotubes have generated great expectations in the scientific arena, mainly due to their spectacular properties, which include a high aspect ratio, high strain resistance, and high strength, along with high conductivities. Nowadays, carbon nanotubes are produced by a variety of methods, each of them with advantages and disadvantages. Once ...
Stoy Paul C - - 2013
Most models of photosynthetic activity assume that temperature is the dominant control over physiological processes. Recent studies have found, however, that photoperiod is a better descriptor than temperature of the seasonal variability of photosynthetic physiology at the leaf scale. Incorporating photoperiodic control into global models consequently improves their representation of ...
Chitra Loganathan - - 2013
The peripheral anionic site (PAS) of acetylcholinesterase (AChE) is involved in amyloid beta (Aβ) peptides aggregation of Alzheimer's disease (AD). AChE exhibits an aryl acylamidase (AAA) activity along with the well known esterase activity. Numerous studies have reported the beneficiary effect of metal chelators in AD treatment. Hence, a comparative ...
Mitjans Marina - - 2013
RATIONALE: The endocannabinoid system has been implicated in the pathogenesis of major depression (MD) as well as in the mediation of antidepressant drug effects. OBJECTIVES: To analyze CNR1 gene variants in MD and clinical response to citalopram (selective serotonin re-uptake inhibitors [SSRI]). METHODS: The role of CNR1 gene (rs806368, rs1049353, ...
López Mónica E - - 2013
BACKGROUND: There is a lack of information about posttreatment care among patients with ductal carcinoma in situ (DCIS). This study compares posttreatment care by ethnicity-language and physician specialty among Latina and White women with DCIS. METHODS: Latina and White women diagnosed with DCIS between 2002 and 2005 identified through the ...
McNeill V Faye - - 2013
Surface-active organic material is a key component of atmospheric aerosols. The presence of surfactants can influence aerosol heterogeneous chemistry, cloud formation, and ice nucleation. We review the current state of the science on the sources, properties, and impacts of surfactants in atmospheric aerosols.
Baloglu Orkun - - 2013
The treatment of pulmonary arterial hypertension (PAH) associated with chronic lung disease of infancy (CLDI) is becoming commonplace. However, an optimal approach to the monitoring of this treatment has not been clearly established, and data suggest that such therapy may not be without risk. This study assessed the feasibility and ...
Schreiber Ulrich - - 2013
A new type of multi-color PAM chlorophyll fluorometer (Schreiber et al. 2012) was applied for measurements of photodamage to photosystem II (PS II) in optically thin suspensions of Chlorella (200 μg Chl l(-1)) in the presence of 1 mM lincomycin. An action spectrum of the relative decrease of F (v)/F (m) in the ...
Li Xiaochun - - 2013
PURPOSE: The success of an epidemiological study for drug safety surveillance or comparative effectiveness depends largely on design and analysis strategies besides data quality. The Observational Medical Outcomes Partnership (OMOP) methods community implemented a collection of statistical methods with extensive parameters allowing a wide variety of designs and analyses. Our ...
Pérez Leirós Claudia - - 2013
Pregnancy challenges immune cells and immunomodulatory circuits of the mother and the developing fetus to dynamically adapt to each other in an homeostatic and tolerant environment for fetal growth. This entails the coordination of multiple cellular processes all devoted to accommodate and nourish the fetus while protecting the mother from ...
Janer Gemma - - 2013
Abstract Little information exists on the toxicological hazards associated to organo-modified clays. We evaluated the cytotoxicity of a series of pristine and organo-modified nanoclays in different cell lines. The calculated IC50 values for cell viability ranged from 1.4 to 47 μg/mL for the six organoclays used and were above 100 ...
Bonvoisin Jacques - - 2013
The electronic and geometrical features of a recently synthesized ruthenium β-diketonato complex with a protected ethynyl ligand ([Ru(dbm)(2)(acac-TIPSA)], dbm = dibenzoylmethanate ion, acac-TIPSA = 3-(triisopropylsilyl)acetylene-2,4-pentanedionate ion), a building block for molecular spintronic devices, were analyzed as a function of its oxidation degree using Density Functional Theory (DFT) and Time Dependent ...
Michaud Andréanne - - 2013
Objective: We tested the hypothesis that high lipolytic responsiveness is related to increased expression of ATM genes in human adipose tissues. Design and Methods: Omental (OM) and subcutaneous (SC) fat samples were obtained surgically in 46 women (age:47.2±4.7 years, BMI: 26.9±5.2 kg/m(2) ). Body composition and fat distribution were measured ...
Bazi Tony - - 2013
INTRODUCTION AND HYPOTHESIS: The aim of this manuscript is to review the subject of urethral dilation (UD) in female patients and to conduct a critical appraisal of the available evidence for its use. METHODS: We used an online search of electronic databases. RESULTS: UD has been cited as a treatment ...
Gowda Srinath T - - 2013
BACKGROUND: To evaluate postdiscovery outcome of coronary artery fistulae (CAF). CAF treatment sequelae and risk factors for coronary thrombosis have not been adequately evaluated. METHODS: Outcome on follow-up of 16 patients with CAF was reviewed. Risk factors for adverse coronary events were assessed based on type, size, and treatment of ...
Kavanagh D O - - 2013
BACKGROUND: This study evaluated the clinicopathological features and survival rates of patients with inflammatory bowel disease who developed colorectal cancer (CRC). METHODS: A retrospective review was performed on a prospectively maintained institutional database (1981-2011) to identify patients with inflammatory bowel disease who developed CRC. Clinicopathological parameters, management and outcomes were ...
Sun Mao - - 2013
BACKGROUND: Some inflammatory factors play an important role in recurrent oral ulceration (ROU). The genetics mechanism of expression level of inflammatory factors is not clear in ROU, but from genetics the expression level of inflammatory factors at least partly depend on the gene polymorphisms. Therfore, we decided to investigate inflammatory ...
Ma Xujun - - 2013
Histone deacetylases (HDACs) mediate histone deacetylation and act in concert with histone acetyltransferases to regulate dynamic and reversible histone acetylation which modifies chromatin structure and function, affects gene transcription, thus, controlling multiple cellular processes. HDACs are widely distributed in almost all eukaryotes, and there have been many researches focusing on ...
Yin Qiuzhen - - 2013
Glacial-interglacial cycles characterized by long cold periods interrupted by short periods of warmth are the dominant feature of Pleistocene climate, with the relative intensity and duration of past and future interglacials being of particular interest for civilization. The interglacials after 430,000 years ago were characterized by warmer climates and higher ...
Ker Yaw-Bee - - 2013
The in vivo chicken embryo model (CEM) demonstrated that gallic acid (GA) induced dysvascularization and hypoxia. Inflammatory edema, Zenker's necrosis, hemolysis, and liposis of cervical muscles were the common symptoms. Levels of the gene hif-1α, HIF-1α, TNF-α, IL-6, and NFκB in cervical muscles were all significantly upregulated, while the vascular ...
Lees P - - 2013
Pradofloxacin is a third-generation fluoroquinolone, licensed in the EU for use in a range of indications in the dog and cat and authorized more recently in the USA for one therapeutic indication (skin infections) in the cat. This review summarizes and appraises current knowledge on the physico-chemical, pharmacological [pharmacokinetics (PK) ...
Jung Ye Lim - - 2013
A label-free, colorimetric method has been developed for ultrasensitive detection of nucleic acids that is based on photoinduced silver ion (Ag(+)) reduction around DNA bases. The assay system is capable of directly detecting bacterial genomic DNA without the need for PCR amplification.
Daien Vincent - - 2013
Purpose:  To assess the relation between retinal vascular caliber and renal function. Patients and methods:  Eighty apparently healthy subjects screened for cardiovascular risk factors (mean age 47 years, 51% female, 36% hypertensive, without diabetes or renal dysfunction) were recruited. Retinal vascular calibers were measured from fundus photographs and expressed as central ...
Martinez-Romero Domingo - - 2013
In this paper the effects of UV treatments on aloin content of Aloe vera L. gel have been analyzed. UV-A treatment to aloe plants for 36 days led to an increase in aloin concentration in gel, rind tissue and latex, while a decrease in chlorophylls a and b occurred in ...
Prieto-Merino D - - 2013
A number of risk scores already exist to predict cardiovascular (CV) events. However, scores developed with data collected some time ago might not accurately predict the CV risk of contemporary hypertensive patients that benefit from more modern treatments and management. Using data from the randomised clinical trial Anglo-Scandinavian Cardiac Outcomes ...
Kala Petr - - 2013
Primary percutaneous coronary intervention is the best treatment of patients with ST elevation myocardial infarction (STEMI). When managing a STEMI patient, our approach must be rapid and aggresive in order to interrupt the pathological process of thrombus formation and stabilization. The therapy must be initiated prior to angiography (pretreatment), continued ...
Popa Nita S - - 2013
In the treatment of oropharyngeal dysphagia, the link between diagnosis and prescription of thickened liquids that are safe to swallow is not always straightforward. Frequently, the capacity to objectively assess and quantify the rheological properties of diagnostic test fluids and to select "rheologically equivalent" dietary products is missing. Perhaps sometimes ...
Frank Jeremy A - - 2013
Bacteriophages encode auxiliary metabolic genes that support more efficient phage replication. For example, cyanophages carry several genes to maintain host photosynthesis throughout infection, shuttling the energy and reducing power generated away from carbon fixation and into anabolic pathways. Photodamage to the D1/D2 proteins at the core of photosystem II necessitates ...
Sentchilo Vladimir - - 2013
Plasmids have long been recognized as an important driver of DNA exchange and genetic innovation in prokaryotes. The success of plasmids has been attributed to their independent replication from the host's chromosome and their frequent self-transfer. It is thought that plasmids accumulate, rearrange and distribute nonessential genes, which may provide ...
Moreno M - - 2013
RATIONALE: Previously we demonstrated reduced D(2/3) receptor availability in the ventral striatum of hyper-impulsive rats on the five-choice serial reaction time task (5-CSRTT). However, the anatomical locus of D(2/3) receptor dysfunction in high impulsive (HI) rats is unknown. OBJECTIVE: In the present study, we investigated whether D(2/3) receptor dysfunction in ...
Hasegawa Akihiko - - 2013
ABSTRACT: INTRODUCTION: Anterior cruciate ligament (ACL) degeneration is observed in most osteoarthritis (OA)-affected knee joints. However, the specific spatial and temporal relationship of these changes and their association with extracellular matrix (ECM) degeneration are not well understood. The objective of this study was to characterize the patterns and relationships of ...
Sato Atsushi - - 2013
Synthetic C-reactive protein (CRP) rescues mice from lethal endotoxin shock or bacterial infection by suppressing tumor necrosis factor (TNF-α), but in turn, enhances Kupffer cell phagocytic activity. We herein assessed the influence of CRP in human peripheral blood mononuclear cells (PBMCs). When human PBMCs were stimulated in vitro with penicillin-treated ...
Edwards Kathryn M - - 2013
The inpatient and outpatient burden of human metapneumovirus (HMPV) infection among young children has not been well established. We conducted prospective, population-based surveillance for acute respiratory illness or fever among inpatient and outpatient children less than 5 years of age in three U.S. counties from 2003 through 2009. Clinical and ...
Silverio Daniel L - - 2013
The discovery of catalysts that can be used to synthesize complex organic compounds by enantioselective transformations is central to advances in the life sciences; for this reason, many chemists aim to discover catalysts that allow for preparation of chiral molecules as predominantly one mirror-image isomer. The ideal catalyst should not ...
Apovian Cm - - 2013
OBJECTIVE: To examine the effects of naltrexone/bupropion (NB) combination therapy on weight and weight-related risk factors in overweight and obese participants. DESIGN AND METHODS: CONTRAVE Obesity Research-II (COR-II) was a double-blind, placebo-controlled study of 1496 obese (body mass index 30-45 kg/m(2) ) or overweight (27-45 kg/m(2) with dyslipidemia and/or hypertension)participants ...
Kotlarz Agnieszka - - 2013
Hsp40 proteins of bacterial and human origin are suspected to be involved in the pathogenesis of rheumatoid arthritis (RA). It has been shown that sera of RA patients contain increased levels of antibodies directed to bacterial and human Hsp40s. The aim of this work was to explore immunological similarities between ...
Canis Martin - - 2013
The main objective of this study is to assess the feasibility of transoral laser microsurgery (TLM) in the treatment of T4a laryngeal cancer and to report the oncological and functional outcomes. This is a retrospective case-series study, held in a single-institute, academic tertiary referral center. Seventy-nine patients with previously untreated ...
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