Search Results
Results 501 - 550 of 3295
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Steigedal Tonje S - - 2013
The peptide hormone gastrin is an important factor for the maintenance and homeostasis of the gastric mucosa. We show that gastrin stimulates proliferation in a dose-dependent manner in the human gastric adenocarcinoma cell line AGS-G(R). Furthermore, we demonstrate that the MAPK scaffold protein MEK partner 1 (MP1) is important for ...
Triadó-Margarit Xavier - - 2013
We analyzed the genetic diversity (18S rRNA gene) of planktonic microbial eukaryotes in 34 different coastal and inland saline ponds. A wide range of environmental conditions was covered with up to thirty fold differences in salinity concentrations (12.5 to 384 g/L), and in situ temperatures (1.3 to 37.5 °C), and ...
Klein Norma J - - 2013
Mastocytosis is an orphan disease rarely encountered by practicing anesthesiologists. Children with mastocytosis often present for procedures or surgery requiring anesthesia. Because many of the medications commonly used in pediatric anesthesia have been reported to initiate mast cell activation, parents are often very anxious about their child's perioperative experience. Laboratory ...
Kareva Irina - - 2013
The conditions that can lead to the exploitative depletion of a shared resource, i.e., the tragedy of the commons, can be reformulated as a game of prisoner's dilemma: while preserving the common resource is in the best interest of the group, over-consumption is in the interest of each particular individual ...
Hyland Rachael M - - 2013
Retinopathy of prematurity (ROP) and infantile hemangiomas are vascular disorders that may share common mechanisms. This study examined a potential clinical association between these disorders in populations of preterm infants at two hospitals in the USA and Hungary. Clinically collected data from infants with gestational ages less than 32 weeks born ...
Siconolfi Daniel E - - 2013
The prevalence of HIV among adults 50 and older in the USA is increasing as a result of improvements in treatment and detection of HIV infection. Substance use by this population has implications for physical and mental health outcomes. We examined patterns of demographics, mental health, and recent substance use ...
McConkey Roy - - 2013
BACKGROUND: Specialist short break services aim to provide enhanced support to family carers as a means of preventing children whose behaviours severely challenge from being placed in full-time residential care. To date, there is limited evidence as to the functioning and effectiveness of such services. METHODS: In all, 17 children ...
Korir Nicholas Kibet - - 2013
Presence of selected tomato (Solanum lycopersicon) microRNAs (sly-miRNAs) was validated and their expression profiles established in roots, stems, leaves, flowers and fruits of tomato variety Jiangshu14 by quantitative RT-PCR (qRT-PCR). In addition conservation characteristics these sly-miRNAs were analyzed and target genes predicted bioinformatically. Results indicate that some of these miRNAs ...
Goyal Shipra - - 2013
PROBLEM: This study was undertaken to evaluate the efficacy and safety of recombinant SP-10 protein for male contraception. METHODS OF STUDY: Adult male mice were divided into five groups. Group I was placebo-treated control while Groups II-V were immunized with recombinant SP-10 protein on day 0 and 21 with different ...
Huillet Thierry E - - 2013
We study a class of coalescents derived from a sampling procedure out of [Formula: see text] i.i.d. Pareto[Formula: see text] random variables, normalized by their sum, including [Formula: see text] -size-biasing on total length effects ([Formula: see text]). Depending on the range of [Formula: see text] we derive the large ...
Koss David J - - 2013
Several genetically engineered models exist that mimic aspects of the pathological and cognitive hallmarks of Alzheimer's disease (AD). Here we report on a novel mouse model generated by targeted knock-in of transgenes containing mutated human amyloid precursor protein (APP) and microtubule-associated protein tau genes, inserted into the HPRT locus and ...
Malhotra Rahul - - 2013
OBJECTIVE: To estimate the expected weight gainthrough midlife for those in a given body mass index (BMI) category in young adulthood. DESIGN AND METHODS: Group-based trajectory modeling and National Longitudinal Study of Youth 1979 data from 1990-2008were used to quantify weight trajectories through midlife for 10,038 young adult men and ...
Matsushita Yumi - - 2013
OBJECTIVE: To examine the incidences of metabolic risk factors according to changes in visceral fat area (VFA) in a large Japanese population. DESIGN AND METHODS: The subjects were 973 men who received a computed tomography (CT) examination in health check-ups twice (2004-2005 and 2007-2008), and not having two or more ...
Ebrahimpour Behnam - - 2013
In this research, a novel homogeneous liquid phase microextraction method was successfully developed based on applying octanoic acid as low density extraction solvent. The method was applied for extraction and determination of chlorophenols as model compounds. Twelve milliliters of the sample solution was poured into a home-designed glass vial. Sixty ...
Haddas R - - 2013
Newcastle disease is a contagious and often fatal disease, capable of affecting all species of birds. A velogenic Newcastle disease virus (vNDV) outbreak occurred in an Israeli zoo, in which Little owls (Athene noctua) and African penguins (Spheniscus demersus) were found positive for presence of NDV. Some of them have ...
Dupont E - - 2013
Since ancient times, human beings have been trying to protect their skin against the adverse effects of the sun. From the first mineral sunscreens used by Egyptians, to the current more sophisticated ultraviolet (UVA/UVB) organic sunscreens, progress has been made in terms of sun protection and deeper knowledge of skin ...
Wu Fenqin - - 2013
Background: Much attention has been paid to the quality of life (QOL) in dialysis patients worldwide. However, differences in QOL between peritoneal dialysis (PD) and hemodialysis (HD) patients have not been clearly identified. The objectives of this study were to compare the differences of QOL between PD and HD patients, ...
Hamanaka Yoshitaka - - 2013
The butterfly Papilio xuthus has compound eyes with three types of ommatidia. Each type houses nine spectrally heterogeneous photoreceptors (R1-R9) that are divided into six spectral classes: ultraviolet, violet, blue, green, red, and broad-band. Analysis of color discrimination has shown that P. xuthus uses the ultraviolet, blue, green, and red ...
Krishtopenko S S - - 2013
We report a theoretical study of the energies of cyclotron resonance (CR) and electron spin resonance (ESR) for fractional quantum Hall states (FQHS) in n-type narrow-gap quantum well (QW) heterostructures. Using the generalized single-mode approximation (GSMA) based on the 8-band k ⋅p Hamiltonian, we calculate the many-body corrections to the ...
Ghassemian Artin - - 2013
We report the total chemical synthesis of human C3a by one-pot native chemical ligation of three unprotected peptide segments, followed by efficient in vitro folding that yielded the anaphylatoxin C3a in high yield and excellent purity. Synthetic C3a was fully active and its crystal structure at 2.1 Å resolution showed ...
Ruzevick J - - 2013
Head and neck squamous cell carcinoma (HNSCC) is notorious for local recurrence and metastatic spread to regional lymph nodes. Distant spread is uncommon, and brain involvement is rare. Over the past decade there has been a rising incidence of HPV-related HNSCC, but it is not known if this escalation has ...
Lampe Christina - - 2013
OBJECTIVE: To analyse diagnostic value of somato-sensory evoked potentials (SEP), magnetic resonance imaging (MRI), and clinical neurological examination in the decision for decompression surgery in mucopolysaccharidosis (MPS) VI patients with craniocervical cord compression (CCJ). METHODS: We retrospectively analysed neurological examination, SEP of the median nerve and MRI outcomes from 31 ...
Chooi Kar Mun - - 2013
Partial genomic sequences of two divergent grapevine leafroll-associated virus 3 (GLRaV-3) variants, NZ1-B and NZ2, from New Zealand were determined and analysed (11,827 nt and 7,612 nt, respectively). At the nucleotide level, both variants are more than 20 % different from the previously published GLRaV-3 sequences, from phylogenetic groups 1 to ...
Fischer Benedikt - - 2013
ABSTRACT: BACKGROUND: Non-medical prescription opioid use (NMPOU) and prescription opioid (PO) related harms have become major substance use and public health problems in North America, the region with the world's highest PO use levels. In Ontario, Canada's most populous province, NMPOU rates, PO-related treatment admissions and accidental mortality have risen ...
Wong Dominic W S - - 2013
A feruloyl esterase (FAE) gene was isolated from a rumen microbial metagenome, cloned into E. coli, and expressed in active form. The enzyme (RuFae2) was identified as a type C feruloyl esterase. The RuFae2 alone released ferulic acid from rice bran, wheat bran, wheat-insoluble arabinoxylan, corn fiber, switchgrass, and corn ...
Dave Abhishek - - 2013
To study the prevalence and systemic control and evaluate the adequacy of therapy of diabetes mellitus (DM) and hypertension (HT) in glaucoma patients visiting a tertiary care eye facility at a university hospital. Consecutive cases with primary open-angle glaucoma (POAG) or primary angle-closure glaucoma (PACG) attending the outpatient services were ...
Mutlu Gül Yesiltepe - - 2013
We present a 10-year-old girl with typical clinical features of H syndrome. Complete agenesis of the inferior vena cava was found on echocardiography and radiologic studies. Mutation analysis of the SLC29A3 gene revealed a novel nonsense mutation. This unique case extends the clinical and mutation spectrum associated with H syndrome ...
Kim Kyung Won - - 2013
Ipilimumab is a novel immunomodulator demonstrating promising efficacy in treatment of melanoma and other cancers. The clinical benefit from ipilimumab can be hampered by the immure-related adverse events (irAEs) caused by dysregulation of host immune system. Ipilimumab associated hepatitis is also an important irAE, however, there have been limited descriptions ...
Stok F Marijn - - 2013
OBJECTIVES: While healthy eating patterns are of high importance in adolescence, most adolescents portray quite unhealthy eating behaviour. One reason for this may be that social norms among peers tend to be unsupportive of healthy eating. The current study investigates whether communicating health-promoting descriptive and injunctive norms influences adolescents' intended ...
Svensson E - - 2013
OBJECTIVE: We conducted a prevalence study to examine the putative association among Caesarean section and BMI in 21 051 adult Danish men born in 1977-1983, who presented for mandatory conscription evaluation around age 18 years. DESIGN AND METHODS: We extracted data on body mass index (BMI) from conscription records, and ...
Wu Yongjun - - 2013
Acetaminophen, also called paracetamol, is found in Tylenol, Excedrin and other products as over-the-counter medicines. In this study, acetaminophen as a luminol signal enhancer was used in the chemiluminescence (CL) substrate solution of horseradish peroxidase (HRP) for the first time. The use of acetaminophen in the luminol-HRP-H(2) O(2) system affected ...
Sjursen Wenche - - 2013
Pheochromocytomas (PHEOs) are neuroendocrine tumours, originating from chromaffin cells in the adrenal medulla. They are either sporadic or hereditary. It is important to identify the hereditary cases, so that patients and relatives with germline mutations can be offered regular surveillance. The objective of this study was the detection of pathogenic ...
Manjari K Sri - - 2013
OBJECTIVE: The aim of the study was to investigate the plasma levels of matrix metalloproteinase-9 (MMP-9), transforming growth factor-β 1 (TGF-β1), and tumor necrosis factor-α (TNF-α) in chronic pancreatitis (CP). METHODS: Blood samples were obtained from 71 patients with CP and 100 control subjects, and plasma levels of MMP-9, TGF-β1, ...
Brandi Giovanni - - 2013
PURPOSES: We conducted a case-control analysis to explore the association between occupational exposure to asbestos and cholangiocarcinoma (CC). METHODS: The study was based on historical data from 155 consecutive patients with CC [69 intrahepatic CC (ICC) and 86 extrahepatic CC (ECC)] referred to Sant'Orsola-Malpighi University Hospital between 2006 and 2010. ...
Klems Joseph P - - 2013
In the nano-aerosol mass spectrometer, individual particles in the 10-30 nm size range are trapped and irradiated with a high pulse energy laser beam. The laser pulse generates a plasma that disintegrates the particle into atomic ions, from which the elemental composition is determined. Particle-to-particle variations among the mass spectra are ...
Dogan Semih - - 2013
Breast cancer survival rates have improved, new disease classifications have been adopted, and increased awareness about symptom management has arisen. Nevertheless, it is unknown to what extent these changes have had any impact on the way clinical trials are conducted. To address this question, the evolution of clinical trials in ...
Jutzi M - - 2013
Asteroid 4 Vesta seems to be a major intact protoplanet, with a surface composition similar to that of the HED (howardite-eucrite-diogenite) meteorites. The southern hemisphere is dominated by a giant impact scar, but previous impact models have failed to reproduce the observed topography. The recent discovery that Vesta's southern hemisphere is ...
Nottingham Andrew T - - 2013
Tropical forests have high rates of soil carbon cycling, but little information is available on how roots, arbuscular mycorrhizal fungi (AMF) and free-living microorganisms interact and influence organic matter mineralisation in these ecosystems. We used mesh in-growth cores and isotopic tracers in phospholipid fatty acid biomarkers (PLFA) to investigate the ...
Islam Salim T - - 2013
Integral membrane proteins with α-helical transmembrane segments (TMS) are known to play important and diverse roles in prokaryotic cell physiology. The net hydrophobicity of TMS directly corresponds to the observed difficulties in expressing and purifying these proteins, let alone producing sufficient yields for structural studies using two-/three-dimensional (2D/3D) crystallographic or ...
Banz-Jansen Constanze - - 2013
PURPOSE: The objective of the study is to investigate recent changes in patient characteristics and treatment procedures of young breast cancer patients over the last 10 years in Germany. METHODS: The study describes the data of 518 patients who were treated adjuvantly between 2008 and 2011 and participated in a resident ...
Sato Fábio Ricardo Loureiro - - 2013
INTRODUCTION: The purpose of the present study was to retrospectively analyze patients with dentofacial deformities attending a reference center in a Brazilian educational institution who sought orthosurgical treatment. MATERIAL AND METHODS: The medical records of 251 patients who sought treatment from 2003 to 2011 at Piracicaba Dental School, State University ...
McEniry Eunan J - - 2013
Tight-binding models derived from density functional theory potentially provide a systematic approach to the development of accurate and transferable models of multicomponent systems. We introduce a systematic methodology for environmental tight binding in which both the overlap and environmental contributions to the electronic structure are included. The parameters of the ...
Tabibian James H - - 2013
PURPOSE: Optimal management of acute gastrointestinal (GI) bleeding requires accurate localization of the bleeding source. The role of technetium-labeled erythrocyte scintigraphy (tagged red blood cell (TRBC) scan) in evaluating acute GI bleeding has been controversial, though recent literature suggests that it is a reliable tool and may be used as ...
Zhao Zhenxiang - - 2013
Abstract Objectives: Given the availability of several statins in the United States, it is important to understand patient characteristics associated with their initiation. We analyzed demographic and clinical factors associated with statin selection among new statin users. Methods: This retrospective cohort study examined factors associated with statin selection among patients ...
Hyo Yukiyoshi - - 2013
Macrolides are widely used at low dosage for long-term therapy of chronic sinusitis. Twenty clinical macrolide-resistant Staphylococcus aureus strains were morphologically compared with 10 clinical macrolide-sensitive strains. PCR amplification was performed to determine the presence of four known macrolide resistance genes. Transmission electron microscopy revealed significantly thicker cell walls in ...
Nowakowski Jan - - 2013
The presence of an oxygen reconstruction on the Cu(001) surface results in the self-metalation of 5,10,15,20-tetraphenylporphyrin (2HTPP) below room temperature (at ∼285 K), in contrast to 2HTPP on the bare Cu(001) substrate, where a temperature of ∼450 K is required. This study demonstrates the decisive impact of a surface reconstruction ...
Pirkkalainen J-M - - 2013
Hybrid quantum systems with inherently distinct degrees of freedom have a key role in many physical phenomena. Well-known examples include cavity quantum electrodynamics, trapped ions, and electrons and phonons in the solid state. In those systems, strong coupling makes the constituents lose their individual character and form dressed states, which ...
Sun Li-Min - - 2013
OBJECTIVE: This study examines the possible association between urinary tract infection (UTI) and urinary tract cancer (UTC). MATERIALS AND METHODS: Data from the National Health Insurance (NHI) system of Taiwan were used for the analysis. The UTI cohort included 70116 patients whom were diagnosed and recruited in the whole country ...
Višnjar Tanja - - 2013
Optimizing culture conditions is known to be crucial for the differentiation of urothelial cell cultures and the formation of the permeability barrier. However, so far, no data exist to confirm if air-liquid (AL) and liquid-liquid (LL) interfaces are physiologically relevant during urothelial differentiation and barrier formation. To reveal the influence ...
Ruth Mr - - 2013
Objective: To develop an algorithm to identify and quantify BAT from PET/CT scans without radiologist interpretation. Design and Methods: Cases (n=17) were randomly selected from PET/CT scans with documented "brown fat" by the reviewing radiologist. Controls (n=18) had no documented "brown fat" and were matched with cases for age [51 ...
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