Search Results
Results 451 - 500 of 3295
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Bijlsma A Y - - 2013
Skeletal muscle is important in insulin-stimulated glucose uptake. Sarcopenia is, therefore, a possible risk factor for insulin resistance. Currently, different diagnostic criteria for sarcopenia include low muscle mass, muscle strength, and walking speed. We assessed these muscle characteristics in relation to insulin resistance in nondiabetics. This cross-sectional study included 301 ...
Percec Virgil - - 2013
The dendronized perylene 3,4:9,10-tetracarboxylic acid bisimide (PBI), (3,4,5)12G1-1-PBI was reported by our laboratory to self-assemble into complex helical columns containing dimers of dendronized PBI with one molecule in each stratum, different intra- and interdimer rotation angles but identical intra- and interdimer distance of 3.5Å, exhibiting a four-strata 21 helical repeat. ...
Mori Hirohito - - 2013
BACKGROUND: No reliable pure natural orifice transluminal endoscopic surgery (NOTES) mechanical counter traction (MCT) device for the flexible endoscope to obtain a sufficient surgical endoscopic field has yet been developed. Our experience with 10 cases of hybrid NOTES prompted the realization of the importance of an MCT device for the ...
Piacenza Massimiliano - - 2013
This paper aims to assess the impact on citizens' well-being of fiscal discipline imposed by the central government on subnational governments. Because healthcare policies involve strategic interactions between different layers of governments in many different countries, we focus on a particular dimension of well-being, namely citizens' health. We model fiscal ...
Altuna Ane - - 2013
While novel influential concepts in neuroscience bring the focus to local activities generated within a few tens of cubic micrometers in the brain, we are still devoid of appropriate tools to record and manipulate pharmacologically neuronal activity at this fine scale. Here we designed, fabricated and encapsulated microprobes for simultaneous ...
Giebler Julia - - 2013
Alkane degrading bacteria were isolated from uncontaminated soil microcosms, which had been incubated with maize litter as natural alkane source. The isolates served to understand spatio-temporal community changes at the soil-litter interface, which had been detected using alkB as a functional marker gene for bacterial alkane degraders. To obtain a ...
Kamiya Kouhei - - 2013
PURPOSE: This study aimed to evaluate whether the image quality of virtual monochromatic spectral imaging with fast kVp switching dual-energy CT (DECT) can be comparable to that of 120-kVp single-energy CT (SECT) without increasing the radiation dose. MATERIALS AND METHODS: We retrospectively identified 15 postoperative patients who had undergone both ...
Walter Maggie C - - 2013
ABSTRACT: BACKGROUND: Dysferlinopathies are autosomal recessive disorders caused by mutations in the dysferlin (DYSF) gene encoding the dysferlin protein. DYSF mutations lead to a wide range of muscular phenotypes, with the most prominent being Miyoshi myopathy (MM) and limb girdle muscular dystrophy type 2B (LGMD2B). METHODS: We assessed the one-year-natural ...
Ivanišević Ivana - - 2013
BACKGROUND: Acute kidney injury (AKI) is a common postoperative complication following cardiopulmonary bypass (CPB) surgery. New biomarkers to identify patients with early AKI (before increases in serum creatinine) are needed to facilitate appropriate treatment. This study aimed to test the role of urinary liver fatty-acid-binding protein (L-FABP) as an early ...
Li Liping - - 2013
Abstract Objective-To determine the role of invariant natural killer T (iNKT) cells in infection-associated pregnancy loss. Methods-B6 and iNKT cell-deficient Jα18(-/-) mice were injected i.p. with LPS or vehicle, and pregnancy outcomes were examined. Decidual iNKT cell expression of CD69 and intracellular cytokine production were analyzed. Mouse decidual iNKT cells ...
Vasconcelos E Sa Debora - - 2013
PURPOSE: High expressed emotion (high-EE), as compared with low-EE, relatives of patients with long-term psychosis may behave in a more controlling manner towards patients. Furthermore, higher levels of behavioural control have been associated with higher relapse rates. We investigated in a recent-onset sample, the extent to which high-EE relatives engage ...
Yu Lin - - 2013
A novel and efficient Cu-promoted decarboxylative direct C3-acylation of N-substituted indoles with α-oxocarboxylic acids for the synthesis of 3-acylindoles was developed.
Fukui Michiaki - - 2013
Recent studies suggested that home arterial stiffness index (HASI) may be a new measure of arterial stiffness. The aim of this study was to investigate whether HASI is more strongly associated with arterial stiffness than is pulse pressure (PP) and thus a more suitable tool than PP for evaluating arterial ...
Minami S B - - 2013
Objectives: To describe two cases of profound hearing loss secondary to enterohaemorrhagic Escherichia coli infection, and to report the efficacy of subsequent cochlear implantation. Results: The first case was a four-year-old girl admitted to hospital with Escherichia coli O157 infection and haemolytic uraemic syndrome. Mild hearing loss was confirmed five ...
Wang S - - 2013
PURPOSE: MicroRNA-31 (miR-31) has different expression patterns in various human cancers. Especially in urothelial carcinoma of the bladder, it has been demonstrated to be decreased expression in the invasive tumors and homozygously deleted. However, its clinical significance in human bladder cancer has not yet been elucidated. Thus, the purpose of ...
Li J - - 2013
Background: To investigate the feasibility of postauricular hypodermic injection for treating inner ear disorders, we compared perilymph pharmacokinetics for postauricular versus intravenous injection, using magnetic resonance imaging, in an animal model. Methods: Twelve albino guinea pigs were divided randomly into two groups and administered gadopentetate dimeglumine via either a postauricular ...
Pokhrel Pallav - - 2013
Adolescence is marked by several key development-related changes, including neurocognitive changes. Cognitive abilities associated with self-regulation are not fully developed until late adolescence or early adulthood whereas tendencies to take risks and seek thrilling and novel experience seem to increase significantly throughout this phase, resulting in a discrepancy between increased ...
Cemal Cingi - - 2013
OBJECTIVE: To analyze and compare the patient satisfaction and quality of life in patients with and without deviated nose deformity who underwent rhinoplasty. DESIGN: Prospective, before-after trial. SETTING: Tertiary referral center. PARTICIPANTS: A total of 191 patients who underwent primary rhinoplasty between 2006-2009 were included. The study population was separated ...
Su Y-Z - - 2013
SUMMARY The aim of this study was to characterize updated HIV subtypes in Yunnan to determine their origins and distribution within the population. RT-PCR of both the gag and env genes were sequenced from Yunnan province inhabitants newly diagnosed with HIV-1. Sequence data from 290 samples were used for statistical ...
Haegeman Bart - - 2013
Quantifying diversity is of central importance for the study of structure, function and evolution of microbial communities. The estimation of microbial diversity has received renewed attention with the advent of large-scale metagenomic studies. Here, we consider what the diversity observed in a sample tells us about the diversity of the ...
Aström Christofer - - 2013
Dengue fever is the most important viral vector-borne disease with ~50 million cases per year globally. Previous estimates of the potential effect of global climate change on the distribution of vector-borne disease have not incorporated the effect of socioeconomic factors, which may have biased the results. We describe an empirical ...
Eid Noura M S - - 2013
Date Palm (Pheonix dactylifera) fruit contain an array of polyphenols, although how these levels alter with cultivar type and fruit ripening is unclear. Utilising HPLC and LC-ESI-MS/MS, we define and quantify an array of hydroxybenzoic acids, hydroxycinnamic acids and flavonoids in three common cultivars of Dates (Ajwa, Barni and Khalas) ...
Mosnier Isabelle - - 2013
The objective of this study was to measure performance benefits obtained by upgrading recipients of the Cochlear™ Nucleus(®) CI24 cochlear implant to the new CP810™ sound processor. Speech recognition in quiet and in spatially separated noise was measured in established users of the Cochlear ESPrit 3G™ (n = 22) and Freedom™ (n = 13) ...
Santamarina-Albertos Alba - - 2013
Circumscribed acral hypokeratosis (CAH) is a rare dermatosis that typically appears as well-dermarcated erythema with a scaly border on the palms or soles of middle-age patients. A pediatric case of CAH has been recently reported in a 10-year-old boy affecting the medial foot since birth. In this report we describe ...
Ikehata Hironobu - - 2013
UVR causes erythema, which has been used as a standardized index to evaluate the risk of UVR for human skin. However, the genotoxic significance of erythema has not been elucidated clearly. Here, we characterized the wavelength dependence of the genotoxic and erythematic effects of UVR for the skin by analyzing ...
Kumbhar Bajarang V - - 2013
Conformational preferences of modified nucleoside, N(4)-acetylcytidine, ac(4)C have been investigated using quantum chemical semi-empirical RM1 method. Automated geometry optimization using PM3 method along with ab initio methods HF SCF (6-31G**), and density functional theory (DFT; B3LYP/6-31G**) have also been made to compare the salient features. The most stable conformation of ...
Gold Avram R - - 2013
OBJECTIVES: A test of the hypothesis that upper airway resistance syndrome (UARS) patients have an increased prevalence of inspiratory airflow limitation (IFL) during sleep compared to healthy controls. METHODS: We compared inspiratory airflow dynamics during sleep between 12 UARS patients (nine females and three males) and 12 healthy controls matched ...
Schley Marcus - - 2013
The nerve fibres underlying histamine-induced itch have not been fully elucidated. We blocked the lateral femoral cutaneous nerve and mapped the skin area unresponsive to mechanical stimulation, but still sensitive to electrically induced pain. Nerve block induced significantly larger anaesthetic areas to mechanical (100 mN pin-prick, 402 ± 61 cm²; brush, 393 ± 63 ...
Agari Yoshihiro - - 2013
SbtR is one of the four TetR family transcriptional regulators present in the extremely thermophilic bacterium, Thermus thermophilus HB8. We identified 10 genes controlled by four promoters with negative regulation by SbtR in vitro. The SbtR-regulated gene products include probable transporters, probable enzymes for sugar or amino acid metabolism, and ...
Kaya Nazife - - 2013
Reactive Green 19 was covalently immobilized onto magnetic nanostructures for purification of alcohol dehydrogenase from Saccharomyces cerevisiae. The Reactive Green 19 immobilized magnetic nanostructures were characterized by Fourier transform infrared spectroscopy, electron spin resonance, atomic force microscope, and energy dispersive X-ray analysis. Particle size of nanostructures was found to be ...
Ahn Kwang H - - 2013
The cannabinoid receptor 1 (CB1), a member of the class A G-protein-coupled receptor (GPCR) family, possesses an observable level of constitutive activity. Its activation mechanism, however, has yet to be elucidated. Previously we discovered dramatic changes in CB1 activity due to single mutations; T3.46A, which made the receptor inactive, and ...
Cui Yong - - 2013
OBJECTIVE: Telomeres are specialized chromatin structures essential for maintenance of chromosomal integrity and stability. Obesity has been proposed to be associated with telomere shortening; however, epidemiologic evidence has been conflicting. We conducted astudy to evaluate the associations of telomere length with various anthropometric indices of general and abdominal obesity, as ...
Strohmeier B - - 2013
BACKGROUND: According to current guidelines, skin testing for hymenoptera venom allergy should be performed in a stepwise manner, maintaining 15- to 20-min intervals between the injections of venom. Given the long-winded procedure of sequential skin testing, we retrospectively explored the safety of simultaneous intradermal testing. METHODS: Four hundred and seventy-eight ...
Jindal Supriya - - 2013
Non-enzymatic glycosylation (glycation) of casein is a process used not just to ameliorate the quality of dairy products but also to increase the shelf life of canned foods, including baby milk supplements. Incubation of κ-casein with reducing sugars for 15 days at physiological temperature showed the formation of a molten globule ...
Noetzli Muriel - - 2013
With the aging population and its rapidly increasing prevalence, dementia has become an important public health concern in developed and developing countries. To date, the pharmacological treatment is symptomatic and based on the observed neurotransmitter disturbances. The four most commonly used drugs are donepezil, galantamine, rivastigmine and memantine. Donepezil, galantamine ...
Jiang Teng - - 2013
Recent works have demonstrated a rare functional variant (R47H) in triggering receptor expressed on myeloid cells (TREM) 2 gene, encoding TREM2 protein, increase susceptibility to late-onset Alzheimer's disease (AD), with an odds ratio similar to that of the apolipoprotein E ε4 allele. The reduced function of TREM2 was speculated to ...
Jafari Mehraneh D - - 2013
BACKGROUND: Laparoscopic surgery has become increasing popular, and its use has been proven safe. However, major vascular injuries during laparoscopic procedures can have devastating effects, and there is a paucity of information regarding their intraoperative management. Here we report our experience with laparoscopic vascular injury repair and analyze the available ...
Donnelly Joseph E - - 2013
OBJECTIVE: Face-to-face weight management is costly and presents barriers for individuals seeking treatment; thus, alternate delivery systems are needed. The objective of this study was to compare weight management delivered by face-to-face (FTF) clinic or group conference calls (phone). DESIGN AND METHODS: Randomized equivalency trial in 295 overweight/obese men/women (BMI ...
Garoz-Ruiz Jesus - - 2013
A new long-optical-pathway spectroelectrochemical cell for absorptometric measurements in the UV-Vis region was developed. This cell consists of two optical fibers brought face to face and fixed on the working electrode support. As a proof of concept, the spectroelectrochemical cell was applied to the determination of catechol using a press-transferred ...
Fan Songhua - - 2013
The clinical significance of SLC7A7 expression remains unclear. In this study, we aimed to explore whether SLC7A7 expression in tumor tissues could be used to assess subsequent prognosis in patients with glioblastoma (GBM). A total of 119 patients with pathologically confirmed GBM and 16 normal controls were recruited for this ...
Fattore Elena - - 2013
We reviewed the scientific literature on the evidence of the relationship between palm oil and adverse effects on human health. Few studies have investigated the effects of palm oil per se, and the main reason why it has been associated with negative health effects is the relatively high content of ...
Shantsila Alena - - 2013
Several studies have suggested that hypertension has a stronger detrimental impact on cardiovascular outcome in lean than in obese persons, but neutral or opposite results have also been reported. We investigated the impact of baseline body mass index (BMI) at presentation with the most severe form of hypertension, that is, ...
Fanti Kostas A - - 2013
Conduct problems (CP) and callous-unemotional (CU) traits can have a long-lasting negative impact into adulthood. Importantly, among youth with CP, those high on CU traits engage in a more severe, aggressive, and persistent pattern of antisocial behavior. The current study investigates the co-occurrence between CP and CU traits among a ...
Pham Anh - - 2013
The effects of hydrogen interstitials and oxygen vacancies on the overall ferromagnetic behaviour of Co doped ZnO (ZnO:Co) have been closely examined using different density functional calculations. The results demonstrate the importance of correcting the bandgap problem of the ZnO host as well as the lack of correlation in Co's ...
Bernardeschi Daniele - - 2013
The objective of this study is to evaluate the anatomical and functional results of rehabilitation of canal wall down (CWD) mastoidectomy using granules of biphasic ceramic. This is a study design retrospective in a tertiary referral centre Fifty-seven patients (59 ears) operated on between 2006 and 2010 of mastoid obliteration ...
Todica Andrei - - 2013
PURPOSE: The purpose of this study is to evaluate left ventricular functional parameters in healthy mice and in different murine models of cardiomyopathy with the novel blood pool (BP) positron emission tomography (PET) tracer [(68)Ga]-albumin. PROCEDURES: ECG-gated microPET examinations were obtained in healthy mice, and mice with dilative (DCM) and ...
Zhang Yi - - 2013
PURPOSE: To evaluate retinal and choroidal blood flow (BF) using high-resolution magnetic resonance imaging (MRI) as well as visual function measured by the electroretinogram (ERG) in patients with retinitis pigmentosa (RP). METHODS: MRI studies were performed in 6 RP patients (29-67 years) and 5 healthy volunteers (29-64 years) on a 3-Tesla scanner ...
Craik Johnathan D - - 2013
Until recently, both the British Society for Haematology and American College of Chest Physicians recommended platelet monitoring in all surgical patients receiving prophylactic low molecular weight heparin (LMWH) for the early diagnosis of heparin-induced thrombocytopenia (HIT). These guidelines were reversed in 2012 based upon an analysis considering resource expenditure, assay ...
Bhutta Mahmood F - - 2013
Collection of saliva for DNA extraction has created new opportunities to recruit participants from the community for genetic association studies. However, sample return rates are variable. No prior study has specifically addressed how study design impacts sample return. Using data from three large-scale genetic association studies we compared recruitment strategy ...
Seng S - - 2013
Background: Hairy polyps are rare congenital growths of the head and neck, mainly found in the nasopharynx and oropharynx. They are made up of two germ cell layers: the ectoderm and mesoderm. Methods: This paper reports a four-month-old who presented with breathing and feeding difficulties. Clinical examination was unremarkable, but ...
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