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Results 401 - 450 of 2387
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Ikeda Atsushi - - 2013
The three different regioisomers of bis-N-methylfulleropyrrolidines have been separated by controlling the relative amounts of gamma-cyclodextrin and DMSO contained in solutions of these compounds. When a small amount of gamma-CDx was used in a mechanochemical high-speed vibration milling apparatus, the trans-1 and trans-2.gamma-CDx complexes were separated from the trans-3.gamma-CDx complex. ...
Pessoa de Santana Phillipe - - 2013
This communication describes a simple and cost-effective method for fabricating glass microchannels by wet chemical etching using masks made by xurography in vinyl adhesive films. Analytical performance of microfluidic devices fabricated using the new approach was evaluated by microchip electrophoresis coupled to capacitively coupled contactless conductivity detection (C(4)D) and laser-induced ...
Hori Sayaka - - 2013
Bacteria form unique ecosystems by coexisting with large organisms. Here we present the first evidence of active flora surrounding xenophyophorea revealed through clone analyses of environmental ribosomal RNA gene sequences. The flora included eight phyla in the xenophyophorean cells with agglutinated test. The major operational taxonomic units were unique from ...
Mellion Sarah A - - 2013
OBJECTIVES:: To evaluate high-dose barbiturates as a second-tier therapy for pediatric refractory intracranial hypertension complicating severe traumatic brain injury. DESIGN:: This is a retrospective cohort study of children with refractory intracranial hypertension treated with high-dose barbiturates. SETTING:: A single center level I pediatric trauma from 2001 to 2010. PATIENTS:: Thirty-six ...
Hotta Kentaro - - 2013
Vesnarinone is a synthetic quinolinone derivative used in the treatment of cardiac failure and cancer. It is also known to cause agranulocytosis as a side effect, which restricts its use, although the mechanism underlying agranulocytosis is not well understood. Here, we show that vesnarinone binds to valosin-containing protein (VCP), which ...
Saridag S - - 2013
SUMMARY Fracture resistance of inlays and onlays may be influenced by the quantity of the dental structure removed and the restorative materials used. The purpose of this in vitro study was to evaluate the effects of two different cavity preparation designs and all-ceramic restorative materials on the fracture resistance of ...
Pérez-Caballero Macarrón C - - 2013
Introduction The management of patients with Fontan physiology who undergo scoliosis surgery is difficult. The purpose of this article was to describe our experience in the management of patients with Fontan circulation undergoing spinal surgery for correction of scoliosis. Materials and methods This was a retrospective study including patients with ...
Selkirk Christina G - - 2013
Purpose: Physicians will play a large role in the delivery of genomic medicine, given the limited number of trained genetics professionals. The objective of this study was to assess physician preparedness for incorporating genomic testing (GT) and pharmacogenetic testing (PT) into practice by determining knowledge, experience, comfort level, and barriers, ...
Mittal Manoj K - - 2013
Objective. To determine if a positive result on pneumography, diagnosis of gastroesophageal reflux disease (GERD), or nontreatment of those diagnosed with GERD with antireflux medications predicts an increased recurrence risk of apparent life-threatening event (ALTE) over the first 4 weeks of follow-up. Methods. Secondary analysis of a prospective, observational study ...
Ryu Ji-Young - - 2013
The isoeugenol monooxygenase (iem) gene from Pseudomonas nitroreducens Jin1, responsible for the conversion of isoeugenol to vanillin, was cloned and overexpressed in Escherichia coli. The purified Iem had a predicted molecular mass of 54 kDa. The V(max), K(M), and k(cat) values for it, using isoeugenol as substrate, were 4.2 µmol ...
Muralidharan Rajanandini - - 2013
Study Design. Retrospective consecutive case seriesObjective. To determine predictors of outcome in patients undergoing surgical treatment of spinal dural arteriovenous fistula (SDAVF).Summary of Background Data. Most previous studies assessing postoperative outcome in patients with SDAVF have been limited due to small population size, lack of sufficient information on presurgical variables, ...
October Tessie W - - 2013
OBJECTIVE:: To compare characteristics of family conferences at the bedside vs. the conference room in the PICU. DESIGN:: Single-site, cohort survey study. SETTING:: Thirty-three bed academic PICU in an urban setting. PARTICIPANTS:: Ten (90.9%) PICU physicians providing care to 29 patients whose families participated in 58 family conferences. MEASUREMENTS AND ...
Yokoyama K - - 2013
BACKGROUND AND PURPOSE:It has not been clarified whether the postoperative resolution of vertebral deformities achieved by KP are superior to those achieved by VP. We compared the outcomes of KP and VP, taking into account the presence of vertebral mobility, to determine whether the balloon inflation in KP may contribute ...
Nguyen Kim N - - 2013
BACKGROUND AND OBJECTIVES: Kidney transplant recipients are at increased risk for malignancies. One recognized risk for malignancy is ionizing radiation. The purpose of this study was to determine, among kidney transplant recipients, the medical imaging procedures that contribute to radiation exposure and their cumulative radiation exposure, as a result of ...
Barreiro Esther - - 2013
Although it has been well characterized that COPD muscle dysfunction is the result of the complex interaction between systemic and local factors, the etiology of muscle dysfunction remains to be fully identified. Interestingly, while hyperinflation and an increased work of breathing appear to be the main contributing events to respiratory ...
Dragović Milan - - 2013
Social tolerance towards left-handed people is commonly accepted in the twenty-first century, though not universal. However, at the level of social cognition a subtle bias against this visible minority group might not have disappeared. To investigate this possibility we adopted the theoretical framework of the stereotype content model (SCM) whereby ...
Miura Masanobu - - 2013
Background: Elevated blood urea nitrogen (BUN) observed in patients hospitalized for acute heart failure syndrome (AHFS) may represent increased neurohumoral activation. The purpose of this study was to examine the prognostic impact of BUN changes during hospitalization on the long-term prognosis of AHFS patients. Methods and Results: The Tohoku Acute Heart Failure ...
Ståhlberg Anders - - 2013
Cells are the basic unit of life and they have remarkable abilities to respond individually as well as in concert to internal and external stimuli in a specific manner. Studying complex tissues and whole organs requires understanding of cell heterogeneity and responses to stimuli at the single-cell level. In this ...
Levy Becca R - - 2013
Ageism has been found to exist throughout a wide variety of societal institutions. Whether it also exists in social networking sites has not been previously considered. To explore this possibility, we conducted a content analysis of each publicly accessible Facebook group that concentrated on older individuals. The site "Descriptions" of ...
Glazer Lilah - - 2013
Gastroliths are transient extracellular calcium deposits formed by the crayfish Cherax quadricarinatus von Martens on both sides of the stomach wall during pre-molt. Gastroliths are made of a rigid chitinous organic matrix, constructed as sclerotized chitin-protein microfibrils within which calcium carbonate is deposited. Although gastroliths share many characteristics with the ...
Chen Zhuo - - 2013
A novel rare mutation, HOXB13 G84E, was reported to co-segregate with prostate cancer (PCa) in hereditary PCa families and associate with PCa risk in unrelated cases and controls. In this study, we aim to compare the G84E mutation frequency among subjects of different races/ethnicities from various geographic regions in the ...
Chutrakul Chanikul - - 2013
Severe chili anthracnose disease in Thailand is caused by Colletotrichum gloeosporioides and C. capsici. To discover anti-anthracnose substances we developed an efficient dual-fluorescent labelling bioassay based on a microdilution approach. Indicator strains used in the assay were constructed by integrating synthetic green fluorescent protein gene (sGFP) and Discosoma sp. red ...
Campo Gianluca - - 2013
ABSTRACT BACKGROUND: there are limited data describing the long-term outcome of patients with concomitant chronic obstructive pulmonary disease (COPD) who develop ST-segment elevation myocardial infarction (STEMI). METHODS: 11,118 consecutive STEMI patients enrolled in the web-based REAL registry (Registro Regionale Angioplastiche Emilia-Romagna) were followed-up and stratified according to COPD presence or ...
Michalczyk Kathryn - - 2013
OBJECTIVE:: Ketamine has a long history of use during pediatric procedural sedation. Concerns about raising intracranial pressure may limit use in certain situations. Whereas some data suggest that benzodiazepine coadministration may blunt this response, pediatric data during procedural sedation do not exist. We evaluated the effects of midazolam pretreatment on ...
Jorfi Mohamed - - 2013
We report quasiclassical trajectory dynamical calculations for the C(3P) + OH(X2)→CO(a3) + H(2S) using a recently developed ab initio potential energy surface for the first electronic state of HCO of 12A" symmetry. The dependence of integral cross sections on the collision energy is determined. Product energy and angular distributions have ...
Song Wensi - - 2013
Loss-of-function diseases are often caused by destabilizing mutations that lead to protein misfolding and degradation. Modulating the innate protein homeostasis (proteostasis) capacity may lead to rescue of native folding of the mutated variants, thereby ameliorating the disease phenotype. In lysosomal storage disorders (LSDs), a number of highly prevalent alleles have ...
Pockett Rhys D - - 2013
Abstract Objective: To quantify the differences in hospital length of stay (LOS) and cost between healthy and vulnerable children with cystic fibrosis (CF), insulin dependent diabetes mellitus (IDDM), cancer, and epilepsy who contract rotavirus (RVGE) or respiratory syncytial virus (RSV). Methods: Hospital Episode Statistics (HES) data were collected for England, ...
Yan Nan - - 2013
The present study examined the possible relationship between classification of professional singing voices and their vocal tract parameters including vocal tract length and volume, and vowel formant frequencies. Acoustic reflection technology (ART) was used to measure vocal tract length and volume of 107 professional singers: 32 tenors, 25 baritones, 27 ...
Pozzoli Alberto - - 2013
This study aimed to report on a non-small-cell lung cancer (NSCLC) originating from the right lung lower lobe and circulatory extension into the left atrium. Atrial involvement is an uncommon feature of advanced NSCLC, occurring in up to 10% of patients with bronchogenic carcinoma. In this case, the neoplastic mass ...
Zou Yanan - - 2013
Lactate dehydrogenase (LDH)-release assay was applied to estimate the toxic potential of harmful algal species at the cellular level. African green monkey kidney (Vero), yellowtail fin epithelia (MJF), and rainbow trout gill (RTgill-W1) cells were used as target cells. A live cell suspension of Karenia mikimotoi (SUO-1) induced the release ...
Coban Jale - - 2013
We investigated the effect of blueberries (BB) on lipids and oxidative stress parameters in hypercholesterolemic guinea pigs. The animals were fed for 75 d on a high-cholesterol (HC) diet supplemented with fresh BB. BB reduced oxidative stress and cholesterol accumulation in the aorta and liver of the guinea pigs. This ...
Nemec Ursula - - 2013
Purpose:To investigate human long bone development in vivo by analyzing distal femoral epimetaphyseal structures and bone morphometrics on magnetic resonance (MR) images of fetuses.Materials and Methods:An institutional review board approved this retrospective study, and informed consent was waived. Included were 272 MR imaging examinations (April 2004-July 2011) in 253 fetuses ...
Weidenaar Alida C - - 2013
Although most children with Acute Myeloid Leukemia (AML) achieve Complete Remission, the relapse rate is 30-40%. Since it is thought that Leukemia Initiating Cells (LICs) are responsible for AML relapses, targeting these cells might improve outcome. Treatment of pediatric AML blasts with the receptor tyrosine kinase (RTK) inhibitor PTK787/ZK 222584 ...
Zhou Houjiang - - 2013
Mass spectrometry (MS)-based proteomics has become the preferred tool for the analysis of protein phosphorylation. To be successful at such an endeavor, there is a requirement for an efficient enrichment of phosphopeptides. This is necessary because of the substoichiometric nature of phosphorylation at a given site and the complexity of ...
Regulacio Michelle D - - 2013
Highly emissive and air-stable AgInS(2)-ZnS quantum dots (ZAIS QDs) with quantum yields of up to 20% have been successfully synthesized directly in aqueous media in the presence of polyacrylic acid (PAA) and mercaptoacetic acid (MAA) as stabilizing and reactivity-controlling agents. The as-prepared water-dispersible ZAIS QDs are around 3 nm in ...
Nelson G - - 2013
BackgroundSouth Africa is the largest producer of platinum group metals in the world. Platinum is found in the Bushveld Complex in the north-east of the country. This volcanic intrusion contains many other minerals, including crystalline silica. Little is known about the health risks in the platinum mining industry.AimsTo explore the ...
Salim Imtiaz - - 2013
Abstract Background: Fasting during the month of Ramadan is a religious obligation that is practiced by millions of people around the world yet there is no clear scientific consensus on its effects on cardiovascular disease. This study was performed to inform physicians as well as patients of evidence based recommendations ...
Zhang Yuhao - - 2013
AIM: This work was done to study the relationship between stock volatility and stroke mortality in Shanghai, China. METHODS: Daily stroke death numbers and stock performance data from 1 January 2006 to 31 December 2008 in Shanghai were collected from the Shanghai Center for Disease Control and Prevention and Shanghai ...
Nassar Boulos - - 2013
ABSTRACT BACKGROUND: The Trendelenburg position is used to distend the central veins, improving both success and safety of vascular cannulation. The purpose of this study was to measure the cross-sectional area (CSA) of the internal jugular vein (IJV) in three different positions using surface ultrasound. METHODS: Fifty one subjects were ...
Shaheen Noha Mohamed Hosni - - 2013
T cell responses against HCV are regulated by the host's human leukocyte antigen (HLA) alleles, which thus are ideal candidate genes to investigate for associations with HCV susceptibility. We aimed to identify associations of HLA DRB1* alleles with HCV infection in a high risk of exposure population, chronic kidney disease ...
Tan Thean Yen - - 2013
Multidrug resistant organisms (MDROs) pose significant infection control challenges in settings with high prevalence and limited isolation facilities. This observational study in an 800-bed hospital determined the prevalence, bacterial density and genetic relatedness of MDROs isolated from ward surfaces, medical devices and hands of healthcare professionals. Targeted MDROs were methicillin-resistant ...
Leithall Rebecca M - - 2013
Structure-property correlations and mechanistic implications play an important role in the design of single-site catalysts for the activation of molecular oxygen. In this study we rationalize trends in catalytic synergy for elucidating the nature of the active site through structural and spectroscopic correlations. In particular, the redox behavior and coordination ...
Zheng Yadong - - 2013
miRNAs, a subclass of small regulatory RNAs, are present from ancient unicellular protozoans to parasitic helminths and parasitic arthropods. The miRNA-silencing mechanism appears, however, to be absent in a number of protozoan parasites. Protozoan miRNAs and components of their silencing machinery possess features different from other eukaryotes, providing some clues ...
Morino Yu - - 2013
Chemical transport models played key roles in understanding the atmospheric behaviors and deposition patterns of radioactive materials emitted from the Fukushima Daiichi nuclear power plant after the nuclear accident that accompanied the great Tohoku earthquake and tsunami on 11 March 2011. However, model results could not be sufficiently evaluated because ...
Henrich Tina - - 2013
ABSTRACT: BACKGROUND: Many parasites show an extraordinary degree of host specificity, even though a narrow range of host species reduces the likelihood of successful transmission. In this study, we evaluate the genetic basis of host specificity and transmission success of experimental F1 hybrids from two closely related tapeworm species (Schistocephalus ...
Kelleher Jerome - - 2013
SUMMARY: Coalescent simulation has become an indispensable tool in population genetics and many complex evolutionary scenarios have been incorporated into the basic algorithm. Despite many years of intense interest in spatial structure, however, there are no available methods to simulate the ancestry of a sample of genes that occupy a ...
Hung Tawny - - 2013
ABSTRACT:: Previous clinical and experimental studies suggested that invasion of the brain by metastatic melanoma may follow the external surfaces of vascular channels, that is, angiotropic extravascular migratory metastasis. Such angiotropic invasion seemss analogous to that of neoplastic glial invasion of the nervous system. We, therefore, have retrospectively investigated 20 ...
Jin Xin - - 2013
Rett syndrome is an autism spectrum disorder resulting from defects in the gene encoding the methyl-CpG-binding protein 2 (MeCP2). Deficiency of the Mecp2 gene causes abnormalities in several systems in the brain, especially the norepinephrinergic and GABA-ergic systems. The norepinephrinergic neurons in the locus coeruleus (LC) modulate a variety of ...
Hussein Fayyad-Kazan - - 2013
ABSTRACT: BACKGROUND: MicroRNAs (miRNAs) are small (19-22-nt) single-stranded noncoding RNA molecules whose deregulation of expression can contribute to human disease including the multistep processes of carcinogenesis in human. Circulating miRNAs are emerging biomarkers in many diseases and cancers such as type 2 diabetes, pulmonary disease, colorectal cancer, and gastric cancer ...
Kim Junsung - - 2013
A gene encoding a novel organic solvent-tolerant alkaline lipase, lipS (GenBank ID JQ071496), was cloned from cold-adapted Pseudomonas mandelii. Recombinant LipS was expressed in Escherichia coli as a 32-kDa soluble protein and was purified by standard procedures. It maintained more than 80% of its activity under alkaline conditions, pH 8-10.5, ...
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