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Lu Jia J Department of Mechanical and Industrial Engineering, The University of Iowa, Iowa City, IA 52242, USA. - - 2013
Predicting pressure induced wall stress in intracranial aneurysms continues to be of interest for aneurysm safety assessment. In quasi-static analysis, there are two distinct approaches that one may take, the forward approach and the inverse approach. The inverse approach starts from a deformed configuration and thus is naturally suited to ...
Ananthakrishnan Ashwin N AN Gastrointestinal Unit, Massachusetts General Hospital Crohn's and Colitis Center, 165 Cambridge Street, 9th Floor, Boston, MA 02114, USA. - - 2013
Abdominal abscesses are a common complication in Crohn's disease (CD). Percutaneous drainage of such abscesses has become increasingly popular and may deliver outcomes comparable to surgical treatment; however, such comparative data are limited from single-center studies. There have been no nationally representative studies comparing different treatment modalities for abdominal abscesses. ...
Scheiermann Christoph C Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, New York 10461, USA. - - 2013
Circadian rhythms, which have long been known to play crucial roles in physiology, are emerging as important regulators of specific immune functions. Circadian oscillations of immune mediators coincide with the activity of the immune system, possibly allowing the host to anticipate and handle microbial threats more efficiently. These oscillations may ...
Nam Hae-Mi HM Department of Infectious Diseases, College of Veterinary Medicine, Konkuk University, 1 Hwayang-dong, Gwangjin-gu, Seoul 143-701, - - 2013
Porcine reproductive and respiratory syndrome virus (PRRSV) induces reproductive failure in sows and respiratory problems in pigs of all ages. Live attenuated and inactivated vaccines are used on swine farms to control PRRSV. However, their protective efficacy against field strains of PRRSV remains questionable. New vaccines have been developed to ...
Sim Ji Ye JY Department of Radiology, Daejin Medical Center Bundang Jesaeng General Hospital, 255-2, Seohyun-dong, Bundang-gu, Sungnam-si, Gyeonggi-do 463-774, Republic of - - 2013
To prospectively estimate the additional diagnostic value of ultrasound (US) re-evaluation for patients with equivocal computed tomography (CT) findings of acute appendicitis. Between April 2011 and October 2011, 869 consecutive patients with suspected appendicitis who were referred for CT were included. The likelihood of appendicitis was prospectively categorized into five ...
Ivo Roland R Department of Orthopaedic and Trauma Surgery, University of Cologne, 50924, Cologne, Germany, - - 2013
Chronic low back pain (CLBP) is one of the most important pain disorders with increasing social and economic implications. Given that CLBP is a multidimensional process associated with comorbidities such as anxiety and depression, treatment of chronic low back pain is still a challenge. Advancement of in vivo brain imaging ...
Bhola Neil E NE Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee, - - 2013
After an initial response to chemotherapy, many patients with triple-negative breast cancer (TNBC) have recurrence of drug-resistant metastatic disease. Studies with TNBC cells suggest that chemotherapy-resistant populations of cancer stem-like cells (CSCs) with self-renewing and tumor-initiating capacities are responsible for these relapses. TGF-β has been shown to increase stem-like properties ...
Hilakivi-Clarke Leena L Department of Oncology, Georgetown University, Washington, DC 20057, USA. - - 2013
Women are using estrogens for many purposes, such as to prevent pregnancy or miscarriage, or to treat menopausal symptoms. Estrogens also have been used to treat breast cancer which seems puzzling, since there is convincing evidence to support a link between high lifetime estrogen exposure and increased breast cancer risk. ...
Pelosin Elisa - - 2013
BACKGROUND: . Action observation influences motor performance in healthy subjects and persons with motor impairments. OBJECTIVE: . To understand the effects of action observation on the spontaneous rate of finger movements in patients with Parkinson disease (PD). METHODS: . Participants, 20 with PD and 14 healthy controls, were randomly divided ...
Guzmán-Fulgencio María - - 2013
ABSTRACT: We performed a cross-sectional study in 469 HIV-infected patients, whose mitochondrial haplogroups were genotyped to study their association with the clinical pattern of AIDS-progression. The chance of not having a AIDS-progression was 1.45 (95% of confidence interval (95%CI)=1.02-2.05); p=0.035) times greater in patients with cluster HV and 1.51 (95%CI=1.06-2.18); ...
Hutchins Andrew Paul - - 2013
Reversible protein ubiquitination regulates virtually all known cellular activities. Here we present a quantitatively evaluated and broadly applicable method to predict eukaryotic ubiquitinating (UBE) and deubiquitinating (DUB) enzymes, and its application to 50 distinct genomes belonging to four of the five major phylogenetic supergroups of eukaryotes: unikonts (including metazoans, fungi, ...
Zaki Muhammad - - 2013
Acute H. pylori infection produces hypochlorhydria. The decrease in acid facilitates survival of the bacterium and its colonization of the stomach. The present study was designed to identify the pathways in oxyntic mucosa by which acute H. pylori infection inhibits acid secretion. In rat fundic sheets in Ussing chamber, perfusion ...
Saxena Vipin - - 2013
The objective of this study was to evaluate the biocompatibility of zirconium phosphate (ZrP) nanoplatelets (NPs), and their use in drug delivery. ZrP and doxorubicin-intercalated ZrP (DOX:ZrP) NPs were characterized by using X-Ray Powder Diffraction (XRPD), Thermogravimetric Analysis (TGA), Transmission Electron Micrography (TEM), Scanning Electron Microscopy (SEM) and Atomic Force ...
Yurttaş Leyla - - 2013
Abstract A new class of novel thiazole-(benz)azole derivatives was synthesized to investigate their anticancer activity. The structure of the compounds was confirmed by IR, (1)H-NMR, and MS spectral data and elemental analyses. Anticancer effect of the compounds was evaluated against A549 and C6 tumor cell lines. MTT, analysis of DNA ...
Ikeda Atsushi - - 2013
The three different regioisomers of bis-N-methylfulleropyrrolidines have been separated by controlling the relative amounts of gamma-cyclodextrin and DMSO contained in solutions of these compounds. When a small amount of gamma-CDx was used in a mechanochemical high-speed vibration milling apparatus, the trans-1 and trans-2.gamma-CDx complexes were separated from the trans-3.gamma-CDx complex. ...
Pessoa de Santana Phillipe - - 2013
This communication describes a simple and cost-effective method for fabricating glass microchannels by wet chemical etching using masks made by xurography in vinyl adhesive films. Analytical performance of microfluidic devices fabricated using the new approach was evaluated by microchip electrophoresis coupled to capacitively coupled contactless conductivity detection (C(4)D) and laser-induced ...
Hori Sayaka - - 2013
Bacteria form unique ecosystems by coexisting with large organisms. Here we present the first evidence of active flora surrounding xenophyophorea revealed through clone analyses of environmental ribosomal RNA gene sequences. The flora included eight phyla in the xenophyophorean cells with agglutinated test. The major operational taxonomic units were unique from ...
Mellion Sarah A - - 2013
OBJECTIVES:: To evaluate high-dose barbiturates as a second-tier therapy for pediatric refractory intracranial hypertension complicating severe traumatic brain injury. DESIGN:: This is a retrospective cohort study of children with refractory intracranial hypertension treated with high-dose barbiturates. SETTING:: A single center level I pediatric trauma from 2001 to 2010. PATIENTS:: Thirty-six ...
Hotta Kentaro - - 2013
Vesnarinone is a synthetic quinolinone derivative used in the treatment of cardiac failure and cancer. It is also known to cause agranulocytosis as a side effect, which restricts its use, although the mechanism underlying agranulocytosis is not well understood. Here, we show that vesnarinone binds to valosin-containing protein (VCP), which ...
Saridag S - - 2013
SUMMARY Fracture resistance of inlays and onlays may be influenced by the quantity of the dental structure removed and the restorative materials used. The purpose of this in vitro study was to evaluate the effects of two different cavity preparation designs and all-ceramic restorative materials on the fracture resistance of ...
Pérez-Caballero Macarrón C - - 2013
Introduction The management of patients with Fontan physiology who undergo scoliosis surgery is difficult. The purpose of this article was to describe our experience in the management of patients with Fontan circulation undergoing spinal surgery for correction of scoliosis. Materials and methods This was a retrospective study including patients with ...
Selkirk Christina G - - 2013
Purpose: Physicians will play a large role in the delivery of genomic medicine, given the limited number of trained genetics professionals. The objective of this study was to assess physician preparedness for incorporating genomic testing (GT) and pharmacogenetic testing (PT) into practice by determining knowledge, experience, comfort level, and barriers, ...
Mittal Manoj K - - 2013
Objective. To determine if a positive result on pneumography, diagnosis of gastroesophageal reflux disease (GERD), or nontreatment of those diagnosed with GERD with antireflux medications predicts an increased recurrence risk of apparent life-threatening event (ALTE) over the first 4 weeks of follow-up. Methods. Secondary analysis of a prospective, observational study ...
Ryu Ji-Young - - 2013
The isoeugenol monooxygenase (iem) gene from Pseudomonas nitroreducens Jin1, responsible for the conversion of isoeugenol to vanillin, was cloned and overexpressed in Escherichia coli. The purified Iem had a predicted molecular mass of 54 kDa. The V(max), K(M), and k(cat) values for it, using isoeugenol as substrate, were 4.2 µmol ...
October Tessie W - - 2013
OBJECTIVE:: To compare characteristics of family conferences at the bedside vs. the conference room in the PICU. DESIGN:: Single-site, cohort survey study. SETTING:: Thirty-three bed academic PICU in an urban setting. PARTICIPANTS:: Ten (90.9%) PICU physicians providing care to 29 patients whose families participated in 58 family conferences. MEASUREMENTS AND ...
Yokoyama K - - 2013
BACKGROUND AND PURPOSE:It has not been clarified whether the postoperative resolution of vertebral deformities achieved by KP are superior to those achieved by VP. We compared the outcomes of KP and VP, taking into account the presence of vertebral mobility, to determine whether the balloon inflation in KP may contribute ...
Barreiro Esther - - 2013
Although it has been well characterized that COPD muscle dysfunction is the result of the complex interaction between systemic and local factors, the etiology of muscle dysfunction remains to be fully identified. Interestingly, while hyperinflation and an increased work of breathing appear to be the main contributing events to respiratory ...
Dragović Milan - - 2013
Social tolerance towards left-handed people is commonly accepted in the twenty-first century, though not universal. However, at the level of social cognition a subtle bias against this visible minority group might not have disappeared. To investigate this possibility we adopted the theoretical framework of the stereotype content model (SCM) whereby ...
Miura Masanobu - - 2013
Background: Elevated blood urea nitrogen (BUN) observed in patients hospitalized for acute heart failure syndrome (AHFS) may represent increased neurohumoral activation. The purpose of this study was to examine the prognostic impact of BUN changes during hospitalization on the long-term prognosis of AHFS patients. Methods and Results: The Tohoku Acute Heart Failure ...
Ståhlberg Anders - - 2013
Cells are the basic unit of life and they have remarkable abilities to respond individually as well as in concert to internal and external stimuli in a specific manner. Studying complex tissues and whole organs requires understanding of cell heterogeneity and responses to stimuli at the single-cell level. In this ...
Levy Becca R - - 2013
Ageism has been found to exist throughout a wide variety of societal institutions. Whether it also exists in social networking sites has not been previously considered. To explore this possibility, we conducted a content analysis of each publicly accessible Facebook group that concentrated on older individuals. The site "Descriptions" of ...
Glazer Lilah - - 2013
Gastroliths are transient extracellular calcium deposits formed by the crayfish Cherax quadricarinatus von Martens on both sides of the stomach wall during pre-molt. Gastroliths are made of a rigid chitinous organic matrix, constructed as sclerotized chitin-protein microfibrils within which calcium carbonate is deposited. Although gastroliths share many characteristics with the ...
Chutrakul Chanikul - - 2013
Severe chili anthracnose disease in Thailand is caused by Colletotrichum gloeosporioides and C. capsici. To discover anti-anthracnose substances we developed an efficient dual-fluorescent labelling bioassay based on a microdilution approach. Indicator strains used in the assay were constructed by integrating synthetic green fluorescent protein gene (sGFP) and Discosoma sp. red ...
Campo Gianluca - - 2013
ABSTRACT BACKGROUND: there are limited data describing the long-term outcome of patients with concomitant chronic obstructive pulmonary disease (COPD) who develop ST-segment elevation myocardial infarction (STEMI). METHODS: 11,118 consecutive STEMI patients enrolled in the web-based REAL registry (Registro Regionale Angioplastiche Emilia-Romagna) were followed-up and stratified according to COPD presence or ...
Michalczyk Kathryn - - 2013
OBJECTIVE:: Ketamine has a long history of use during pediatric procedural sedation. Concerns about raising intracranial pressure may limit use in certain situations. Whereas some data suggest that benzodiazepine coadministration may blunt this response, pediatric data during procedural sedation do not exist. We evaluated the effects of midazolam pretreatment on ...
Jorfi Mohamed - - 2013
We report quasiclassical trajectory dynamical calculations for the C(3P) + OH(X2)→CO(a3) + H(2S) using a recently developed ab initio potential energy surface for the first electronic state of HCO of 12A" symmetry. The dependence of integral cross sections on the collision energy is determined. Product energy and angular distributions have ...
Song Wensi - - 2013
Loss-of-function diseases are often caused by destabilizing mutations that lead to protein misfolding and degradation. Modulating the innate protein homeostasis (proteostasis) capacity may lead to rescue of native folding of the mutated variants, thereby ameliorating the disease phenotype. In lysosomal storage disorders (LSDs), a number of highly prevalent alleles have ...
Pockett Rhys D - - 2013
Abstract Objective: To quantify the differences in hospital length of stay (LOS) and cost between healthy and vulnerable children with cystic fibrosis (CF), insulin dependent diabetes mellitus (IDDM), cancer, and epilepsy who contract rotavirus (RVGE) or respiratory syncytial virus (RSV). Methods: Hospital Episode Statistics (HES) data were collected for England, ...
Yan Nan - - 2013
The present study examined the possible relationship between classification of professional singing voices and their vocal tract parameters including vocal tract length and volume, and vowel formant frequencies. Acoustic reflection technology (ART) was used to measure vocal tract length and volume of 107 professional singers: 32 tenors, 25 baritones, 27 ...
Pozzoli Alberto - - 2013
This study aimed to report on a non-small-cell lung cancer (NSCLC) originating from the right lung lower lobe and circulatory extension into the left atrium. Atrial involvement is an uncommon feature of advanced NSCLC, occurring in up to 10% of patients with bronchogenic carcinoma. In this case, the neoplastic mass ...
Zou Yanan - - 2013
Lactate dehydrogenase (LDH)-release assay was applied to estimate the toxic potential of harmful algal species at the cellular level. African green monkey kidney (Vero), yellowtail fin epithelia (MJF), and rainbow trout gill (RTgill-W1) cells were used as target cells. A live cell suspension of Karenia mikimotoi (SUO-1) induced the release ...
Coban Jale - - 2013
We investigated the effect of blueberries (BB) on lipids and oxidative stress parameters in hypercholesterolemic guinea pigs. The animals were fed for 75 d on a high-cholesterol (HC) diet supplemented with fresh BB. BB reduced oxidative stress and cholesterol accumulation in the aorta and liver of the guinea pigs. This ...
Weidenaar Alida C - - 2013
Although most children with Acute Myeloid Leukemia (AML) achieve Complete Remission, the relapse rate is 30-40%. Since it is thought that Leukemia Initiating Cells (LICs) are responsible for AML relapses, targeting these cells might improve outcome. Treatment of pediatric AML blasts with the receptor tyrosine kinase (RTK) inhibitor PTK787/ZK 222584 ...
Zhou Houjiang - - 2013
Mass spectrometry (MS)-based proteomics has become the preferred tool for the analysis of protein phosphorylation. To be successful at such an endeavor, there is a requirement for an efficient enrichment of phosphopeptides. This is necessary because of the substoichiometric nature of phosphorylation at a given site and the complexity of ...
Regulacio Michelle D - - 2013
Highly emissive and air-stable AgInS(2)-ZnS quantum dots (ZAIS QDs) with quantum yields of up to 20% have been successfully synthesized directly in aqueous media in the presence of polyacrylic acid (PAA) and mercaptoacetic acid (MAA) as stabilizing and reactivity-controlling agents. The as-prepared water-dispersible ZAIS QDs are around 3 nm in ...
Nelson G - - 2013
BackgroundSouth Africa is the largest producer of platinum group metals in the world. Platinum is found in the Bushveld Complex in the north-east of the country. This volcanic intrusion contains many other minerals, including crystalline silica. Little is known about the health risks in the platinum mining industry.AimsTo explore the ...
Salim Imtiaz - - 2013
Abstract Background: Fasting during the month of Ramadan is a religious obligation that is practiced by millions of people around the world yet there is no clear scientific consensus on its effects on cardiovascular disease. This study was performed to inform physicians as well as patients of evidence based recommendations ...
Zhang Yuhao - - 2013
AIM: This work was done to study the relationship between stock volatility and stroke mortality in Shanghai, China. METHODS: Daily stroke death numbers and stock performance data from 1 January 2006 to 31 December 2008 in Shanghai were collected from the Shanghai Center for Disease Control and Prevention and Shanghai ...
Nassar Boulos - - 2013
ABSTRACT BACKGROUND: The Trendelenburg position is used to distend the central veins, improving both success and safety of vascular cannulation. The purpose of this study was to measure the cross-sectional area (CSA) of the internal jugular vein (IJV) in three different positions using surface ultrasound. METHODS: Fifty one subjects were ...
Shaheen Noha Mohamed Hosni - - 2013
T cell responses against HCV are regulated by the host's human leukocyte antigen (HLA) alleles, which thus are ideal candidate genes to investigate for associations with HCV susceptibility. We aimed to identify associations of HLA DRB1* alleles with HCV infection in a high risk of exposure population, chronic kidney disease ...
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