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Bagaria Dinesh - - 2013
BACKGROUND: Laparoscopic cholecystectomy has become the gold standard for treatment of symptomatic gallstone disease. Nonresolution of dyspepsia postoperatively is of major concern nowadays. The present study was conducted to study the effect of laparoscopic cholecystectomy on gastric emptying in symptomatic gallstone disease using (99m)Tc sulfur colloid scintigraphy. This pilot study ...
Wang Youhua - - 2013
Ski-interacting protein (SKIP) is a highly conserved protein from yeast to Human. As an essential spliceosomal component and transcriptional co-regulator it plays an important role in preinitiation, splicing and polyadenylation. SKIP can also combine with Ski to overcome the G1 arrest and the growth-suppressive activities of pRb. Furthermore SKIP has ...
Zuo Ming-Liang - - 2013
BACKGROUND: Early identification of individuals who are at risk of developing atrial fibrillation (AF) and ischemic stroke may enable a closer surveillance and thus prompt initiation of oral anticoagulation for stroke prevention. OBJECTIVE: This study sought to investigate whether congestive heart failure, hypertension, age ≥ 75 years, diabetes, previous stroke (CHADS(2)) and CHA(2)DS(2)-vascular ...
Hong Mei M Department of Chemistry and Ames Laboratory, Iowa State University , Ames, Iowa 50011, United - - 2013
The determination of molecular structures using solid-state NMR spectroscopy requires distance measurement through nuclear-spin dipole-dipole couplings. However, most dipole-coupling techniques compete with the transverse (T2) relaxation of the nuclear spins, whose time constants are at most several tens of milliseconds, which limits the ability to measure weak dipolar couplings or ...
Sangwan Vinod K - - 2013
The full potential of graphene in integrated circuits can only be realized with a reliable ultra-thin high-ĸ top-gate dielectric. Here, we report the first statistical analysis of the breakdown characteristics of dielectrics on graphene, which allows the simultaneous optimization of gate capacitance and the key parameters that describe large-area uniformity ...
Ganguly Archan A Department of Biological Sciences, Neuroscience Program, Ohio University, 213 Life Science Building, Athens, OH, 45701, USA. - - 2013
The cAMP signaling pathway mediates synaptic plasticity and is essential for memory formation in both vertebrates and invertebrates. In the fruit fly Drosophila melanogaster, mutations in the cAMP pathway lead to impaired olfactory learning. These mutant genes are preferentially expressed in the mushroom body (MB), an anatomical structure essential for ...
Aydin Kadriye - - 2013
Acromegaly's effect on voice is still indefinite. We aimed to define acoustic characteristics of patients with acromegaly. Cross-sectional case-control study was designed. Thirty-seven patients with acromegaly and 30 age- and sex-matched healthy controls were included. Fundamental frequency (F(0)) and measurements related to frequency, amplitude, noise and tremor of the obtained ...
Mermigkis Charalampos - - 2013
PURPOSE: The multi-organ involvement of mitochondrial diseases means that patients are likely to be more vulnerable to sleep disturbances. We aimed to assess if early recognition and treatment of obstructive sleep apnea (OSA) in patients with Leigh disease may influence primary disease outcome. METHODS: We describe a case of adult-onset ...
Saito Arata - - 2013
Carcinogenicity of ethyl tertiary-butyl ether (ETBE) was examined with inhalation exposure using F344/DuCrlCrlj rats. Groups of 50 male and 50 female rats, 6 week old at commencement, were exposed to ETBE at 0, 500, 1,500 or 5,000 ppm (v/v) in whole-body inhalation chambers for 6 h/day, 5 days/week for 104 weeks. A significant increase ...
Alves Raquel Duarte Moreira - - 2013
PURPOSE: To evaluate the effects of two dietary patterns in which carbohydrates and proteins were eaten mostly at lunch or dinner on body weight and composition, energy metabolism, and biochemical markers in overweight/obese men. METHODS: Fifty-eight men (30.0 ± 7.4 years; 30.8 ± 2.4 kg/m(2)) followed a covert hypocaloric balanced diet (-10 % of daily energy requirements) ...
Lisi Sabrina - - 2013
The chemokine GRO-α and its receptor CXCR2 are associated with the chronic inflammation in Sjögren's syndrome (SS). To better understand the molecular mechanisms by which the GRO-α/CXCR2 system is involved in the SS inflammatory condition, our studies were designed to clarify the role of ADAM17 activation in the modulation of ...
Kwon Elena N - - 2013
This study aimed to determine whether quantification of subpulmonary stenosis (SPS) in tetralogy of Fallot (TOF) in the second-trimester fetus can predict postnatal clinical outcome measured by pulmonary valve size and/or timing or type of intervention. The study retrospectively identified fetuses with TOF from 1998 to 2010 diagnosed at 26 weeks ...
Sørensen Morten Draeby - - 2013
OBJECTIVE: Cells of foetal origin circulating in the maternal peripheral bloodstream present a unique source for non-invasive prenatal diagnostics. The aims of this study were to raise antibodies against identified circulating foetal cells from the maternal blood, test the properties of these antibodies and to determine the foetal cell type ...
Cohen Alexander T - - 2013
The clinically appropriate duration of thromboprophylaxis in hospitalized patients with acute medical illnesses is unknown. In this multicenter, randomized, double-blind trial, we evaluated the efficacy and safety of oral rivaroxaban administered for an extended period, as compared with subcutaneous enoxaparin administered for a standard period, followed by placebo. We randomly ...
Lee Myungmo - - 2013
An efficient enantioselective synthetic method for the synthesis of (2R)-5-phenyl-2-alkylproline tert-butyl esters was reported. The phase-transfer catalytic alkylation of tert-butyl-5-phenyl-3,4-dihydro-2H-pyrrole-2-carboxylate in the presence of chiral quaternary ammonium catalysts gave the corresponding alkylated products (up to 97% ee). The following diastereoselective reductions afforded chiral 5-phenyl-2-alkylprolines which can be applied to asymmetric ...
Martínez-Olmos Miguel Angel - - 2013
INTRODUCTION: Anorexia nervosa (AN) is characterised by a refusal to normal body weight accompanied by a marked restriction of food intake, frequently leading to severe malnutrition. In severe malnutrition and wasting syndromes, mucosal atrophy, altered gastrointestinal motility and pancreatic atrophy, which alter digestive function and can exacerbate malnutrition, have been ...
So Min Wook - - 2013
High-dose steroids, immunosuppressants such as cyclophosphamide and cyclosporine, and high-dose intravenous immunoglobulin have all been used to control hemophagocytic lymphohistiocytosis (HLH) or autoimmune hemolytic anemia (AIHA) associated with systemic lupus erythematosus (SLE); however, some patients are refractory to treatment. Rituximab has successfully resolved many of the refractory manifestations of SLE. ...
Maurizi Palma - - 2013
BACKGROUND: Children with acute lymphoblastic leukemia (ALL) undergo multiple lumbar punctures (LPs) during their course of treatment for diagnostic and therapeutic purposes. LP is a stressful and painful procedure, affecting the quality of life of these children. Procedural analgo-sedation might improve the child's comfort and prevent the child's movements, reducing ...
Hamilton Patricia A PA ClinStat Consulting LLC, 2492 Manchester Ave., Cardiff by the Sea, CA 92007, USA. - - 2013
This study compared readings from two professional-grade, commercially available infrared (IR) thermometers, the ThermoScan® PRO 4000 prewarmed tip ear thermometer and the Temporal Scanner(™) TAT-5000 temporal artery thermometer. The repeatability and precision of readings from IR thermometers for professional use were questioned in the past, but in recent years, these ...
Dubsky M - - 2013
AIMS: The aim of our study was to compare the effect of bone marrow mononuclear cells (BMMNC) and peripheral blood progenitor cells (PBPC) therapy in patients with diabetic foot disease (DFD) and critical limb ischemia (CLI) unresponsive to revascularization with conservative therapy. METHODS: Twenty eight patients with DFD (17 treated ...
Fridman Sophie - - 2013
The development of a novel three-dimensional image analysis technique of stacks generated by confocal laser scanning microscopy is described allowing visualization of mitochondria-rich cells (MRCs) in the seawater-adapted Nile tilapia in relation to their spatial location. This method permits the assessment and classification of both active and nonactive MRCs based ...
Herman Paulo - - 2013
BACKGROUND: Despite accumulated experience and advancing techniques for laparoscopic hepatectomy, surgeons still face challenging resections that require specific and innovative intraoperative maneuvers [1-3]. The right posterior sectionectomy presents special concerns about its location, the extensive transection area, and the difficult access to the pedicle [4, 5]. The intrahepatic Glissonian approach ...
Caraty A - - 2013
Recent studies demonstrated that kisspeptin (Kp) administration, given as a slow constant infusion of Kp10 (the shortest endogenous form of the kp molecules which carries biological activity), is able to stimulate gonadotrophin secretion and induce ovulation in anoestrus acyclic ewes. Detailed analysis of peripheral luteinising hormone (LH) concentrations, obtained at ...
Vasconcelos Helena - - 2013
PURPOSE: To evaluate morphological and functional chorioretinal changes 5 years after standard photodynamic therapy (PDT) for chronic central serous chorioretinopathy (CSC). METHODS: A retrospective, nonrandomized study, including patients with chronic CSC treated with standard PDT and followed for at least 60 months. All patients underwent a complete ophthalmological examination, and the location ...
Downs Gregory S - - 2013
Here we present a genome-wide overview of transcriptional circuits in the agriculturally significant crop species Zea mays. We examined transcript abundance data at 50 developmental stages, from embryogenesis to senescence, for 34,876 gene models and classified genes into 24 robust coexpression modules. Modules were strongly associated with tissue types and ...
Scapicchio Pier Luigi - - 2013
Abstract Choline alphoscerate (alpha-GPC) is a semisynthetic derivative of phosphatidylcholine with central parasympathomimetic action. This action is at the basis of its use in pathologies characterized by cognitive deficits of neurodegenerative or vascular nature. In a number of clinical studies alpha-GPC demonstrated benefit in patients with cognitive dysfunction. In light ...
Hammond Ashley S - - 2013
Hip joint diameter is highly correlated with body size in primates and so can potentially provide important information about the biology of fossil hominins. However, quantifying hip joint size has been difficult or impossible for many important but fragmentary specimens. New three-dimensional technologies can be used to digitally fit spheres ...
Deguchi Ayumi - - 2013
Black color in flowers is a highly attractive trait in the floricultural industry, but its underlying mechanisms are largely unknown. This study was performed to identify the bases of the high accumulation of anthocyanidins in black cultivars and to determine whether the high accumulation of total anthocyanidins alone leads to ...
Antoniou Stavros A SA Center for Minimally Invasive Surgery, Hospital Neuwerk, Mönchengladbach, Germany. - - 2013
Trocar-associated visceral injuries are rare but potentially fatal complications of laparoscopic access. More commonly, abdominal wall bleeding occurs, which usually requires hemostatic measures and prolongs operative time. Blunt-tipped trocars have been postulated to carry a lower risk of abdominal wall bleeding and intra-abdominal injuries. The aim of the present systematic ...
Chan Yap-Hang - - 2013
PURPOSE: Epidemiological studies showed that PR prolongation is associated with increased risk of adverse cardiovascular outcomes. We investigated the relations of PR interval with indices of vascular function and endothelial repair as the underlying mechanisms. METHODS: The study comprised 348 high-risk patients with prior coronary artery disease, ischemic stroke, and/or ...
Chun Joong-Hyun JH Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Building 10, Room B3 C346A, 10 Center Drive, Bethesda, MD 20892-1003, - - 2013
No-carrier-added [(18)F]fluoroarenes were synthesized through the radiofluorination of diaryl sulfoxides with [(18)F]fluoride ion. Diaryl sulfoxides bearing a para electron-withdrawing substituent readily gave the corresponding 4-[(18)F]fluoroarenes in high RCYs. This process broadens the scope for preparing novel (18)F-labeling synthons and PET radiotracers.
Kolovskaya Olga S - - 2013
Salmonella is one of the most dangerous and common foodborne pathogens. The overuse of antibiotics for disease prevention has led to the development of multidrug resistant Salmonella. Now more than ever, there is a need for new antimicrobial drugs to combat these resistant bacteria. Aptamers have grown in popularity since ...
Li Zhili - - 2013
Porcine epidemic diarrhea virus (PEDV) causes acute diarrhea and dehydration with high mortality rates in swine. It has become increasingly problematic in China. Since the nucleocapsid (N) protein is highly conserved, it is a candidate protein for early diagnosis and vaccine development. In this study, the N genes of 15 ...
Järventausta Petri J - - 2013
Purpose:  To evaluate the efficacy of keratectomy in treating irregular astigmatism caused by peripheral hypertrophic subepithelial corneal degeneration (PHSD) and to study the possible underlying immunological risk factors. Materials and methods:  Patients (14 eyes) with diagnosed PHSD were treated with superficial keratectomy with or without the assistance of phototherapeutic keratectomy ...
Hong Yun-Chul - - 2013
The aim of this study was to evaluate the role of polymorphisms of renin-angiotensin system (RAS) genes in modulating outdoor temperature-related blood pressure (BP) responses. Data for RAS gene polymorphisms, BP and outdoor temperature were collected from 4903 subjects from February 2003 to August 2004. Generalized additive and linear models ...
He Feng - - 2013
According to the Milankovitch theory, changes in summer insolation in the high-latitude Northern Hemisphere caused glacial cycles through their impact on ice-sheet mass balance. Statistical analyses of long climate records supported this theory, but they also posed a substantial challenge by showing that changes in Southern Hemisphere climate were in ...
Suebsing Rungkarn - - 2013
AIMS: Enterocytozoon hepatopenaei is an emerging microsporidian parasite that has been linked to recent losses caused by white feces syndrome (WFS) in cultivated giant or black tiger shrimp Penaeus (Penaeus) monodon and whiteleg shrimp Penaeus (Litopenaeus) vannamei in Asia. To more accurately assess its impact on shrimp production and to ...
Hoenig Elisa - - 2013
The implantation of osteochondral constructs - tissue-engineered (TE) cartilage on a bone substitute carrier - is a promising method to treat defects in articular cartilage. Currently, however, the TE-cartilage's mechanical properties are clearly inferior to those of native cartilage. Their improvement has been the subject of various studies, mainly focusing ...
Zheng Fangfang - - 2013
Nasopharyngeal carcinoma (NPC) is a common malignancy in southern China without defined etiology. Recent studies have shown that TGFBR3, a transforming growth factor type III receptor, exhibits anti-cancer activities. This study was to investigate the effects of TGFBR3 on NPC growth and the mechanisms for its actions. Effects of TGFBR3 ...
Hodges-Simeon Carolyn R - - 2013
Background: Age at menarche is often used to measure maturational tempo in girls. Unfortunately, no parallel marker exists for boys. It is suggested that voice change has a number of advantages as a marker of the timing and degree of male pubertal development. Aim: Traditional auxological methods are applied to ...
Jia Shaodong - - 2013
INTRODUCTION: Conventional liquid chromatographic methods coupled with ultraviolet or evaporative light scattering detection are not sensitive enough to determine both polar and less polar ginsenosides at low concentrations. OBJECTIVE: To establish a liquid chromatography-charged aerosol detection method for the simultaneous determination of polar and less polar ginsenosides in a variety ...
Resende Rosa - - 2013
Alzheimer's disease, the most prevalent age-related neurodegenerative disease, is characterized by the presence of extracellular senile plaques composed of amyloid-beta (Aβ) peptide and intracellular neurofibrillary tangles. More than 50 % of Alzheimer's disease (AD) patients also exhibit abundant accumulation of α-synuclein (α-Syn)-positive Lewy bodies. This Lewy body variant of AD (LBV-AD) ...
Kasas Sandor - - 2013
Recently, atomic force microscope (AFM) manufacturers have begun producing instruments specifically designed to image biological specimens. In most instances, they are integrated with an inverted optical microscope, which permits concurrent optical and AFM imaging. An important component of the set-up is the imaging chamber, whose design determines the nature of ...
Wang Kai - - 2013
Objective. This study was to evaluate the relationship of atherosclerotic renal artery stenosis (ARAS) with extracranial carotid arteries atherosclerosis (ECAS) and intracranial cerebral atherosclerosis (ICAS) in ischemic stroke (IS) patients. Methods. This study was a prospective cohort analysis of consecutive patients with IS who had not a history of renal ...
Bourgoin-Voillard Sandrine - - 2013
The kinetic method is a widely used approach for the determination of thermochemical data such as proton affinities (PA) and gas-phase acidities (ΔH° ( acid )). These data are easily obtained from decompositions of noncovalent heterodimers if care is taken in the choice of the method, references used, and experimental ...
Okamura Toshiya - - 2013
The modifying effects of 4-methylthio-3-butenyl isothiocyanate (MTBITC) and curcumin were investigated in N-nitrosobis(2-oxopropyl)amine (BOP)-initiated hamsters. Male 6-week-old Syrian hamsters were subcutaneously injected with 10 mg/kg body weight (b.w.) of BOP four times a week, and fed a diet supplemented with 80 mg/kg diet of MTBITC, equivalent to 4.6 mg/kg b.w./day ...
Paciorkowski Alex R AR Department of Neurology, Pediatrics, and Biomedical Genetics, Center for Neural Development & Disease, University of Rochester Medical Center, 601 Elmwood Ave, Rochester, NY 14642, USA. - - 2013
MEF2C haploinsufficiency syndrome is an emerging neurodevelopmental disorder associated with intellectual disability, autistic features, epilepsy, and abnormal movements. We report 16 new patients with MEF2C haploinsufficiency, including the oldest reported patient with MEF2C deletion at 5q14.3. We detail the neurobehavioral phenotype, epilepsy, and abnormal movements, and compare our subjects with ...
Yu Li-Qing - - 2013
Here we report a covalent bonding approach to fabricate a robust metal-organic framework ZIF-90 coating for solid-phase microextraction. The ZIF-90 bonded fiber exhibits high enhancement factors, wide linearity, excellent reproducibility, and good lifetime for the studied polar endocrine disruptors.
El-Arabi Tarek F - - 2013
ABSTRACT: BACKGROUND: Comparatively little information is available on members of the Myoviridae infecting low G+C content, Gram-positive host bacteria of the family Firmicutes. While numerous Bacillus phages have been isolated up till now only very few Bacillus cereus phages have been characterized in detail. RESULTS: Here we present data on ...
Ioannou Savvas - - 2013
ABSTRACT: BACKGROUND: Limited data suggest that fluorine-18 fluoro-2-deoxy-D-glucose (F-18 FDG) positron emission tomography combined with computed tomography (PET/CT) scan may be useful for diagnosing infections of the spine. Brucellar spondylodiskitis might be devastating and current imaging techniques lack sensitivity and specificity. The aim of this prospective study was to determine ...
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