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Results 351 - 400 of 2969
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Ishida H - - 2013
BACKGROUND: According to the 7th edition of the TNM staging system, stage IV metastatic colorectal cancer (CRC) at the time of initial diagnosis is sub-classified into stage IVA or IVB disease. Peritoneal carcinomatosis (PC), considered to have a dismal prognosis, is exclusively sub-classified into stage IVB, even though other metastases ...
Sato Rumi - - 2013
About 85 % of patients with generalized myasthenia gravis (MG) have anti-nicotinic acetylcholine receptor (nAChR) antibodies in their sera (seropositive MG; SPMG). The other 15 % (seronegative MG; SNMG) are also considered to have antibody-mediated disease, but the nature of the antibodies in SNMG is not fully understood. We investigated the effect ...
Bagaria Dinesh - - 2013
BACKGROUND: Laparoscopic cholecystectomy has become the gold standard for treatment of symptomatic gallstone disease. Nonresolution of dyspepsia postoperatively is of major concern nowadays. The present study was conducted to study the effect of laparoscopic cholecystectomy on gastric emptying in symptomatic gallstone disease using (99m)Tc sulfur colloid scintigraphy. This pilot study ...
Wang Youhua - - 2013
Ski-interacting protein (SKIP) is a highly conserved protein from yeast to Human. As an essential spliceosomal component and transcriptional co-regulator it plays an important role in preinitiation, splicing and polyadenylation. SKIP can also combine with Ski to overcome the G1 arrest and the growth-suppressive activities of pRb. Furthermore SKIP has ...
Zuo Ming-Liang - - 2013
BACKGROUND: Early identification of individuals who are at risk of developing atrial fibrillation (AF) and ischemic stroke may enable a closer surveillance and thus prompt initiation of oral anticoagulation for stroke prevention. OBJECTIVE: This study sought to investigate whether congestive heart failure, hypertension, age ≥ 75 years, diabetes, previous stroke (CHADS(2)) and CHA(2)DS(2)-vascular ...
Hong Mei - - 2013
The determination of molecular structures using solid-state NMR spectroscopy requires distance measurement through nuclear-spin dipole-dipole couplings. However, most dipole-coupling techniques compete with the transverse (T(2)) relaxation of the nuclear spins, whose time constants are at most several tens of milliseconds, which limits the ability to measure weak dipolar couplings or ...
Faubladier Céline - - 2013
The present study aimed at (1) describing age-related changes in faecal bacterial functional groups involved in carbohydrate degradation and in their activities in foals (n 10) from birth (day (d) 0) to 6 months (d180) and (2) investigating the effect of maternal supplementation (five mares per treatment) from d - 45 to ...
Liem Dennis - - 2013
PURPOSE: Arthroscopic double-row (DR) suture anchor repair of rotator cuff tears has been shown to be superior to most single-row (SR) techniques with regard to footprint reconstruction, load to failure and tendon-to-bone contact pressures. The hypothesis of this study was that the greater contact pressures of DR techniques would compromise ...
Reis Mauro - - 2013
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) has been identified as a key enzyme involved in glycolysis processes for energy production in the Trypanosoma cruzi parasite. This enzyme catalyses the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) in the presence of inorganic phosphate (Pi) and nicotinamide adenosine dinucleotide (NAD+). The catalytic mechanism used by GAPDH ...
Wang Qianlong - - 2013
Synthesis under hydrofluorothermal conditions produces new iron, manganese and vanadium fluorosulfates; these include the isomorphous Na(3)M(III)F(2)(SO(4))(2), M = V, Mn, Fe, with a sheet-like structure formed of linked M(III)F(2)O(4) and SO(4) polyhedra separated by sodium ions which may be extracted electrochemically at potentials of >3.5 V.
Driscoll Andrea - - 2013
AIMS AND OBJECTIVES: To compare the efficacy of chronic heart failure management programmes (CHF-MPs) according to a scoring algorithm used to quantify the level of applied interventions-the Heart Failure Intervention Score (HF-IS). BACKGROUND: The overall efficacy of heart failure programmes has been proven in several meta-analyses. However, the debate continues ...
Hwang Joo-Yeon - - 2013
Gastric cancer (GC) is the most common malignancy. The incidence rates remain remarkably high in East Asians. Although genome-wide association studies in the Han Chinese and Japanese populations have so far yielded susceptibility loci for GC, these findings need to be validated in an independent ethnic group. To identify the ...
Feng Yongqiang - - 2013
A paramagnetic Sc(3)NC@C(80) anion radical was obtained by chemical reduction. ESR spectrometry and theoretical calculations disclosed that the core NC moiety takes possession of the unpaired electron and stabilizes the paramagnetic species. It is the first time a paramagnetic metal cyanide metallofullerene has been obtained.
Richter Holly E - - 2013
INTRODUCTION AND HYPOTHESIS: Our aim was to characterize pelvic floor symptoms in postmenopausal women who had undergone osteoporosis evaluation and examine their association with bone mineral density (BMD). METHODS: Pelvic floor symptom questionnaires were mailed to 4,026 women. Multivariate logistic regression models controlling for age, race, body mass index (BMI), ...
O'Colmain Una - - 2013
Purpose:  To investigate the clinical features of all patients with acute-onset diplopia presenting to the ophthalmology department. Methods:  The notes of every patient who presented with acute onset (<4-week duration) diplopia to the ophthalmology clinic over a 2-year period were reviewed. Data regarding clinical features, underlying aetiology, past medical history, ...
Klosterbuer Abby S - - 2013
Fibre has been shown to exert a number of benefits on gastrointestinal (GI) health, yet its intake is low. Addition of novel fibres to food products may increase fibre intake and improve gut health. The objective of the present study was to evaluate the influence of three novel fibres on ...
Idrees Atif S M - - 2013
Upon exposure to nitrogen-containing bisphosphonates (N-BPs) such as zoledronic acid (Zol), human tumor cells increase susceptibility to γδ T cell-mediated cytotoxicity. Based on this finding, much attention has been paid to tumor immunotherapy using γδ T cells and N-BPs. Although Zol can render a wide variety of human tumor cells ...
Ramos Languren L E - - 2013
Changes in synaptic efficacy and morphology are considered as the downstream mechanisms of consolidation of memories and other adaptive behaviors. In the last decade, neurotrophin-3 (NT-3) has emerged as one potent mediator of synaptic plasticity. In the adult brain, expression of NT-3 is largely confined to the hippocampal dentate gyrus ...
Shi Guiying - - 2013
A simple and rapid capillary electrophoresis (CE) with an acidic potassium permanganate chemiluminescence (CL) detection method was developed to determine three alkaloids (curine, sinomenine and magnoflorine) simultaneously. A laboratory-built CE-CL detection interface was used. The field-amplified sample stacking technique was applied to the online concentration of alkaloids. Experimental conditions for ...
Chen B - - 2013
This study was designed to compare the effects of alendronate (ALN), strontium ranelate (SR), and zoledronic acid (ZOL) on bone-implant osseointegration in ovariectomized rats. Histological examination and biomechanical tests show that ZOL, ALN, and SR enhance bone-implant osseointegration; ALN and SR have similar effects, while ZOL enhances bone-implant osseointegration more ...
Pemp Berthold - - 2013
Purpose:  The aim of the study was to compare the diameter of the central retinal artery (CRA) between patients with diabetes mellitus and healthy subjects in vivo. CRA diameters were calculated from retinal haemodynamic parameters measured with noninvasive measurement techniques. Methods:  Sixteen patients with type 1 diabetes with no or ...
Mosnaim Aron D - - 2013
Phenylethylamine and its monomethylated derivatives p-methylphenylethylamine, α-methylphenylethylamine, phenylethylamine itself, N-methylphenylethylamine, o-methylphenylethylamine, and β-methylphenylethylamine, readily cross the blood-brain barrier showing a brain-uptake index (%) ± SD (water considered 100 %), of 108 ± 11, 98 ± 14, 83 ± 6, 78 ± 11, 62 ± 7 and 56 ± 6, respectively (injection of tritiated water and 100 μg standard amine, which was measured by gas-liquid chromatography). Similar ...
Panwar Bharat - - 2013
ABSTRACT: BACKGROUND: The vitamins are important cofactors in various enzymatic-reactions. In past, many inhibitors have been designed against vitamin binding pockets in order to inhibit vitamin-protein interactions. Thus, it is important to identify vitamin interacting residues in a protein. It is possible to detect vitamin-binding pockets on a protein, if ...
Walton S - - 2013
The standard method for assessing blood cell characteristics using an ocular micrometer is time-consuming and limited. We used the Nikon NIS Elements imaging software and May- Grünwald-Giemsa staining to determine whether automated image analysis is suitable for rapid and accurate quantitative morphometry of erythrocytes. Blood was collected during four seasons ...
Abu El-Asrar Ahmed M - - 2013
Purpose:  To determine the expression of the endogenous anti-angiogenic and pro-fibrotic matricellular protein thrombospondin (TSP)-2 and its receptors CD36 and CD47 in proliferative diabetic retinopathy (PDR). In addition, we examined the expression of TSP-2 in the retinas of diabetic rats. Methods:  Epiretinal membranes from 14 patients with PDR and nine ...
Ueno Hiroshi - - 2013
Metal encapsulation into a cage and chemical modification on the outer surface of fullerenes endow them with some unique characteristic properties. Although the derivatization of endohedral fullerenes holds promise for producing novel new nano-carbon materials, there are few reports about such compounds. Herein, we report the synthesis of lithium encapsulated ...
Lan Shubin - - 2013
Biological soil crusts (BSCs) perform vital ecosystem services, but the difference in biological components or developmental level still affects the rate and type of these services. In order to differentiate crust successional stages in quantity and analyze the relationship between crust developmental level and successional stages, this work determined several ...
Amini Farahnaz - - 2013
The combination of two silent mutations, c.1311C>T in exon 11 and IVS11 T93C (glucose-6-phosphate dehydrogenase (G6PD) 1311T/93C), with unknown mechanism, have been reported in G6PD-deficient individuals in Asian populations including Malaysian aboriginal group, Negrito. Here, we report the screening of G6PD gene in 103 Negrito volunteers using denaturing high-performance liquid ...
Detopoulou Paraskevi - - 2013
Heart failure (HF) is a complex syndrome with cardiac, renal, neurohormonal and sympathetic nervous system's manifestations, the pathogenesis of which among others is connected to inflammation. PAF has local and systemic effects pertaining to HF progression since it causes a negative inotropic effect, it induces arrhythmias, it induces apoptosis and ...
Jeong Chang Wook - - 2013
BACKGROUND: Previously, the authors demonstrated the feasibility of a pure transvesical natural orifice translumenal endoscopic surgery (NOTES) for uterine horn resection (UHR) using a rigid ureteroscope in swine as an appendectomy model. However, visualization was poor, and there was room for improvement. The authors have assessed the feasibility and safety ...
Burmeister Christine Friederike - - 2013
Planetary ball mills are well known and used for particle size reduction on laboratory and pilot scales for decades while during the last few years the application of planetary ball mills has extended to mechanochemical approaches. Processes inside planetary ball mills are complex and strongly depend on the processed material ...
Kohro Takahide - - 2013
The Japanese Society of Hypertension (JSH) updated its hypertension management guidelines in 2009. One of the most significant changes with respect to the 2004 version was the stance towards the use of diuretics: in 2004, their use was cautioned against, but in 2009, it was actively promoted. The purpose of ...
Boerner Leigh J K - - 2013
Thermal Bergman cyclization of Pt(ii) dialkynylporphyrins reveals a marked reduction in the cyclization temperature relative to the free base and Zn(ii) derivatives. In contrast, photogenerated (3)ππ* population produces no detectable Bergman photocyclization, suggesting that the photoreactivities of the related free base and Zn(ii) derivatives occurs via the (1)ππ* state.
Deng Shengyuan - - 2013
A novel ferrocenyl-terminated dendrimer with an electron-relay framework was designed as an efficient tracing tag to quench the cathodic electrochemiluminescence emission of quantum dots, which led to a dual quenching effect via both electron and energy transfer for construction of a sensitive bioanalysis strategy.
Silveira Bruna Maria - - 2013
OBJECTIVE: The present study investigated how trans-fat is reported on the packaging of foods sold in a Brazilian supermarket. DESIGN: The present descriptive, cross-sectional study analysed the ingredient list, nutrition facts label and claims of no trans-fat on the packaging. SETTING: A large supermarket in Florianópolis, Brazil. SUBJECTS: All food ...
Low James A - - 2013
Background: We describe the experience of managing the dying moments of a nursing home patient via telemedicine. Case presentation: Ms. C was a 92-year-old frail woman with multiple medical problems, living in a nursing home. She spent her final days in the nursing home, choosing not to be transferred to ...
Muller Matthew D - - 2013
When exposed to a cold environment, a barehanded person experiences pain, cold sensation, and reduced manual dexterity. Both acute (e.g. exercise) and chronic (e.g. cold acclimatization or habituation) processes might lessen these negative effects. The purpose of this experiment was to determine the effect of cold habituation on physiology, perception, ...
Liebert Melissa A - - 2013
Background: Market integration (MI), the suite of social and cultural changes that occur with economic development, has been associated with negative health outcomes such as cardiovascular disease; however, key questions remain about how this transition manifests at the local level. Aim: The present paper investigates the effects of MI on ...
Kumar Ajit - - 2013
A pyrimidine-naphthalene anchored Schiff base (receptor ) showed Al(3+) selective conformational arrest by inhibition of its C[double bond, length as m-dash]N isomerization (cis-trans) leading to its fluorescent switching in aqueous medium. Nevertheless the H(2)PO(4)(-)/HSO(4)(-) bailed receptor from the Al(3+) arrest leading to its switching 'off'. This conformational arrest and bail ...
Scullin Michael K - - 2013
Hypertension affects many older adults and is associated with impaired neural and cognitive functioning. We investigated whether a history of hypertension was associated with impairments to prospective memory, which refers to the ability to remember to perform delayed intentions, such as remembering to take medication. Thirty-two cognitively normal older adult ...
Shi Wendian - - 2013
Leukocyte differential count is one of the most frequently ordered clinical tests in hospitals. This paper reports a point-of-care test for the leukocyte count by using a microflow cytometer and a fluorescent dye assay. The dye assay relied on fluorescent detection alone to count leukocytes in blood and to identify ...
Aoki Kazuhiro - - 2013
The progress in imaging technology with fluorescent proteins has uncovered a wide range of biological processes in developmental biology. In particular, genetically-encoded biosensors based on the principle of fluorescence resonance energy transfer (FRET) have been used to visualize spatial and temporal dynamics of intracellular signaling in living cells. However, development ...
Robeva Ralitsa - - 2013
Systemic lupus erythematosus (SLE) is an autoimmune disorder that affects mainly females. Therefore, interrelations between the reproductive and immune system have been assumed. Considering the complex influence of hormones and receptors, we aimed to investigate the influence of androgens and androgen receptor (AR) polymorphism in women with SLE. One hundred ...
Zavitsanou Katerina - - 2013
Brain inflammation in early life has been proposed to play important roles in the development of anxiety and psychosis-related behaviours in adulthood, behaviours that rely on the integrity of dopamine and /or serotonin systems. Moreover recent behavioural and anatomical evidence suggests involvement of CB1 receptors in the control of emotion ...
Haselboeck J - - 2013
Data on the in vivo function of platelets induced by the thrombopoietin receptor agonist eltrombopag are scarce. To assess a possible influence of eltrombopag we compared platelet function of eltrombopag-treated immune thrombocytopenia (ITP) patients (group 1; n=10) after treatment response to that from control ITP patients (group 2; n=12). We ...
Naitoh Sae - - 2013
The relationship between Y-chromosome single-nucleotide polymorphisms (SNPs) registered in the Japanese SNP (JSNP) database (http://snp.ims.u-tokyo.ac.jp) and Y-binary haplogroup lineages was investigated to identify new Y-chromosomal binary haplogroup markers and further refine Y-chromosomal haplogroup classification in the Japanese population. We used SNPs for which it was possible to construct primers to ...
Miller Seth - - 2013
BACKGROUND: Single-incision laparoscopic colectomy (SILC) is touted to be an improved approach for minimally invasive surgery although no data currently exists regarding the acquisition of skills for the safe performance of this technique. The authors report their early experience with proctoring of surgical residents in SILC by experienced colorectal surgeons. ...
Storr-Paulsen Allan - - 2013
Purpose:  To investigate corneal endothelial cell density and morphology in type II diabetic and non-diabetic patients and to relate potential differences to the glycaemic status. Methods:  A prospective clinical study including 107 patients with type II diabetes and 128 non-diabetic patients. Sample size was based on a power calculation (power = 0.90; ...
Dangel K C - - 2013
Knowledge of natural Anguillicola infections of Short-finned eels (Anguilla australis) in New Zealand is very limited. So far, no study contains data on all life cycle stages of Anguillicola novaezelandiae in naturally infected eels. In order to study the frequency of A. novaezelandiae in New Zealand Short-finned eels, we examined ...
MacDougall A S - - 2013
Long-term and persistent human disturbances have simultaneously altered the stability and diversity of ecological systems, with disturbances directly reducing functional attributes such as invasion resistance, while eliminating the buffering effects of high species diversity. Theory predicts that this combination of environmental change and diversity loss increases the risk of abrupt ...
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