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Results 251 - 300 of 2982
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Akbari S Hassan A - - 2013
PURPOSE: Variation exists in the surgical methods employed for decompression of Chiari II malformation (CIIM), yet an evaluation of these techniques has not been performed. The purpose of this study was to assess the efficacy of bony decompression (cervical laminectomy alone versus suboccipital craniectomy with laminectomy) with or without dural ...
Thanassoulis George G Department of Medicine and the Research Institute, McGill University Health Centre, - - 2013
Limited information is available regarding genetic contributions to valvular calcification, which is an important precursor of clinical valve disease. We determined genomewide associations with the presence of aortic-valve calcification (among 6942 participants) and mitral annular calcification (among 3795 participants), as detected by computed tomographic (CT) scanning; the study population for ...
Faubladier Céline - - 2013
The present study aimed at (1) describing age-related changes in faecal bacterial functional groups involved in carbohydrate degradation and in their activities in foals (n 10) from birth (day (d) 0) to 6 months (d180) and (2) investigating the effect of maternal supplementation (five mares per treatment) from d - 45 to ...
Liem Dennis - - 2013
PURPOSE: Arthroscopic double-row (DR) suture anchor repair of rotator cuff tears has been shown to be superior to most single-row (SR) techniques with regard to footprint reconstruction, load to failure and tendon-to-bone contact pressures. The hypothesis of this study was that the greater contact pressures of DR techniques would compromise ...
Reis Mauro - - 2013
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) has been identified as a key enzyme involved in glycolysis processes for energy production in the Trypanosoma cruzi parasite. This enzyme catalyses the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) in the presence of inorganic phosphate (Pi) and nicotinamide adenosine dinucleotide (NAD+). The catalytic mechanism used by GAPDH ...
Wang Qianlong - - 2013
Synthesis under hydrofluorothermal conditions produces new iron, manganese and vanadium fluorosulfates; these include the isomorphous Na(3)M(III)F(2)(SO(4))(2), M = V, Mn, Fe, with a sheet-like structure formed of linked M(III)F(2)O(4) and SO(4) polyhedra separated by sodium ions which may be extracted electrochemically at potentials of >3.5 V.
Driscoll Andrea - - 2013
AIMS AND OBJECTIVES: To compare the efficacy of chronic heart failure management programmes (CHF-MPs) according to a scoring algorithm used to quantify the level of applied interventions-the Heart Failure Intervention Score (HF-IS). BACKGROUND: The overall efficacy of heart failure programmes has been proven in several meta-analyses. However, the debate continues ...
Hwang Joo-Yeon - - 2013
Gastric cancer (GC) is the most common malignancy. The incidence rates remain remarkably high in East Asians. Although genome-wide association studies in the Han Chinese and Japanese populations have so far yielded susceptibility loci for GC, these findings need to be validated in an independent ethnic group. To identify the ...
Feng Yongqiang - - 2013
A paramagnetic Sc(3)NC@C(80) anion radical was obtained by chemical reduction. ESR spectrometry and theoretical calculations disclosed that the core NC moiety takes possession of the unpaired electron and stabilizes the paramagnetic species. It is the first time a paramagnetic metal cyanide metallofullerene has been obtained.
Richter Holly E - - 2013
INTRODUCTION AND HYPOTHESIS: Our aim was to characterize pelvic floor symptoms in postmenopausal women who had undergone osteoporosis evaluation and examine their association with bone mineral density (BMD). METHODS: Pelvic floor symptom questionnaires were mailed to 4,026 women. Multivariate logistic regression models controlling for age, race, body mass index (BMI), ...
O'Colmain Una - - 2013
Purpose:  To investigate the clinical features of all patients with acute-onset diplopia presenting to the ophthalmology department. Methods:  The notes of every patient who presented with acute onset (<4-week duration) diplopia to the ophthalmology clinic over a 2-year period were reviewed. Data regarding clinical features, underlying aetiology, past medical history, ...
Arey Bruce W - - 2013
This study examines the nature of highly fragile reaction products that form in low water content supercritical carbon dioxide (scCO2) using a combination of focus ion beam/scanning electron microscopy, confocal Raman spectroscopy, helium ion microscopy (HeIM), and transmission electron microscopy (TEM). HeIM images show these precipitates are fragile rosettes. Using ...
Johansson Jessica - - 2013
Monoaminergic dysregulation is implicated in attention-deficit/hyperactivity disorder (ADHD), and methylphenidate and amphetamines are the most frequently prescribed pharmacological agents for treating ADHD. However, it has recently been proposed that the core symptoms of the disorder might be due to an imbalance between monoaminergic and cholinergic systems. In this study, we ...
Zhang Yong Y Division of Molecular Pharmaceutics, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, CB# 7362, 120 Mason Farm Rd, Chapel Hill, NC 27599-7362, - - 2013
Diethylenetriamine pentaacetic acid penta-ethyl ester, designated as C2E5, was successfully incorporated into a nonaqueous gel for transdermal delivery. The thermal and rheological properties of a formulation containing 40% C2E5, 20% ethyl cellulose, and 40% Miglyol 840® prepared using the solvent evaporation method demonstrated that the gel had acceptable content uniformity ...
Altintop Mehlika D - - 2013
In the present study, new pyrazoline derivatives were synthesized via the reaction of 1-(chloroacetyl)-3-(2-furyl)-5-aryl-2-pyrazolines with sodium salts of N,N-disubstituted dithiocarbamic acids. Each derivative was evaluated for its ability to inhibit acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) using a modification of Ellman's spectrophotometric method. The compounds were also investigated for their cytotoxic ...
Khambaty Tasneem - - 2013
BACKGROUND: Depression and anxiety have been linked to periodontal disease, an emerging risk factor for chronic diseases. However, this literature is mixed, and few studies have concurrently evaluated depression and anxiety. PURPOSE: We simultaneously examined the associations of depressive and anxiety disorders with periodontal disease prevalence and explored tobacco use ...
Motta L - - 2013
A 12-month-old female neutered crossbreed was referred for investigation of seizure-like episodes occurring only at intense exercise. Thorough medical, neurological and cardiac investigations were performed and excluded the most commonly known causes of seizure-like activity. The dog was fitted with an ambulatory electrocardiography device and underwent another exercise-induced seizure. The ...
Naranjo Diana P - - 2013
Attractive toxic sugar bait (active ingredient, 1 % boric acid) was evaluated against Aedes albopictus Skuse populations in the laboratory, semi-field trials, and field trials in residential communities in St. Augustine, Florida. Laboratory evaluations of boric acid sugar baits applied to the plant Pentas lanceolata (Rubiaceae) demonstrated 100 and 92 % mortality ...
Toh Sengwee S Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA 02215, USA. - - 2013
This study aims to estimate the prevalence of and temporal trends in prenatal antipsychotic medication use within a cohort of pregnant women in the U.S. We identified live born deliveries to women aged 15-45 years in 2001-2007 from 11 U.S. health plans participating in the Medication Exposure in Pregnancy Risk ...
Allweiler Sandra I - - 2013
OBJECTIVE: To investigate reproductive health issues for women working in veterinary anesthesia compared with those working in veterinary critical care. Reproductive health issues were classified as time to conceive, fertility treatment, miscarriage, and children with birth defects. STUDY DESIGN: Questionnaire-based survey. METHODS: A survey was designed to assess the reproductive ...
Beck-Nielsen S S - - 2013
Bone mineral apparent density (BMAD) in children with X-linked hypophosphatemia (XLH) was evaluated, as they are unlikely to have extra-skeletal ossifications contributing to the elevated bone mineral density of the spine in adult patients. Children with XLH also had significantly higher BMAD of the spine compared to femoral neck. INTRODUCTION: ...
Georgescu Ion - - 2013
BACKGROUND: Natural orifice translumenal endoscopic surgery (NOTES) could offer multiple advantages compared with the laparoscopic approach. One such potential advantage, not yet proven, is the inferior inflammatory response, which translates into less significant operative stress. This study aimed to compare the immuno-inflammatory response between transgastric NOTES and laparoscopy for simple ...
Guo Bin - - 2013
Peanut agglutinin (PNA) and Ulex europaeus agglutinin-1 (UEA-1) were used as probes to study the distribution of β-gal (1→3) ga1Nac and α-l-Fucose in rabbit uterus during early pregnancy. PNA binding was mainly localized on the surface of uterine glandular and luminal epithelium. There were no positive signals on day 1 ...
Yang Jeyul - - 2013
INTRODUCTION: Intracranial pial arteriovenous fistula (AVF) is a rare cerebrovascular lesion, and the literature is sparse. Most authors insist that simple disconnection of arteriovenous shunting is enough to treat intracral single-channel pial AVF in most cases, either by microsurgery or endovascular embolization without resection of entire vascular malformation. DISCUSSION: We ...
MacDougall A S - - 2013
Long-term and persistent human disturbances have simultaneously altered the stability and diversity of ecological systems, with disturbances directly reducing functional attributes such as invasion resistance, while eliminating the buffering effects of high species diversity. Theory predicts that this combination of environmental change and diversity loss increases the risk of abrupt ...
Mechaly Adva - - 2013
Amplified Luminescent Proximity Homogeneous Assay (AlphaLISA) technology is an energy-transfer-based assay, utilizing singlet oxygen as an energy donor to a fluorescent acceptor. The long singlet oxygen migration distance allows the energy transfer mechanism to go up to ∼200 nm, facilitating flexible and sensitive homogeneous immunoassays. While soluble protein detection using AlphaLISA ...
Arnetz Lisa - - 2013
Excess cortisol and GH induce insulin resistance, a central feature of type 2 diabetes (T2D). To study whether the insulin sensitizer pioglitazone affects basal cortisol levels and the GH-IGF-I axis in patients with T2D. Forty-eight patients with T2D (men/women = 28:20, age 61 ± 1 years, BMI 31 ± 0.6 kg/m(2)) were treated for 26 weeks with pioglitazone 30-45 mg ...
Pohlmann Adriana Raffin - - 2013
Poly(ϵ-caprolactone) (PCL), a biodegradable and biocompatible polymer, is useful to encapsulate a wide range of drugs making it an interesting material for the preparation of carriers with potential applications in therapeutics. The design and development of those carriers to modulate drug release, to improve the drug stability or apparent solubility ...
Zhang Zewu - - 2013
Mesoporous anatase-phase TiO(2) hollow shells were successfully fabricated by the solvothermal and calcination process. This method involves preparation of SiO(2)@TiO(2) core-shell colloidal templates, sequential deposition of carbon and then silica layers through solvothermal and sol-gel processes, crystallization of TiO(2) by calcination and finally removal of the inner and outer silica ...
Fuster V - - 2013
Background: Low weight and premature deliveries arouse clinical interest concerning the survival of newborns. The determinants of birth weight among Spanish natives and immigrants may differ. Research which considers maternal origin and associated factors such as age and parity is important. Aim: This study analyses and models the influence of ...
Xafis Vicki - - 2013
BACKGROUND: Laparoscopic skills development via simulation-based medical education programs has gained support in recent years. However, the impact of training site type on skills acquisition has not been examined. The objective of this research was to determine whether laparoscopic skills training outcomes differ as a result of training in a ...
Zhang Ruiling - - 2013
Genetic, epigenetic, and environmental factors influence the development of alcohol dependence (AD). Recent studies have shown that DNA methylation markers in peripheral blood may serve as risk markers for AD. Yet a genome-wide epigenomic approach investigating the role of DNA methylation in AD has yet to be performed. We conducted ...
Cichowski Sara B - - 2013
INTRODUCTION AND HYPOTHESIS: To determine whether fecal incontinence (FI) is associated with sexual activity and to compare sexual function in women with and without FI. METHODS: We conducted a retrospective chart review of all new patients seen in an academic urogynecology clinic. Women who reported fecal incontinence, as defined by ...
de Oliveira Fábio Morato - - 2013
We investigated the prevalence of TET2 deletion by using a new FISH probe in a cohort of 362 Brazilian patients with myeloid neoplasms and their association with cytogenetic information (G-banding analysis). Normal karyotype was observed in 45.8 % of MDS (n = 44), 43.8 % of AML (n = 39) and 46.3 % of MPN (n = 82). Abnormalities ...
Deyle D R DR Departments of Medicine, University of Washington, Seattle, WA 98195, - - 2013
Integrating vectors can lead to the dysregulation of nearby chromosomal genes, with important consequences for clinical trials and cellular engineering. This includes the retroviral and lentiviral vectors commonly used for deriving induced pluripotent stem cells (iPSCs). We previously used integrating foamy virus (FV) vectors expressing OCT4, SOX2, MYC and KLF4 ...
Athe Ramesh - - 2013
OBJECTIVE: To combine evidence from randomized controlled trials to assess the effect of Fe-fortified foods on mean Hb concentration in children (<10 years). DESIGN: We conducted a meta-analysis of randomized, controlled, Fe-fortified feeding trials that evaluated Hb concentration. The weighted mean difference was calculated for net changes in Hb by ...
Kim Eun Key - - 2013
BACKGROUND: TRAM breast reconstruction is commonly thought to be inadequate for underweight patients and LD flap with implant is usually recommended. However, it is often difficult to find an appropriate implant for thin Asian women with small breasts. The authors present the results of using TRAM flap alone for immediate ...
Ghorai Manas K - - 2013
An efficient and practical strategy for the synthesis of highly functionalized racemic and non-racemic 4,5-dihydropyrroles via domino ring opening cyclization (DROC) of activated aziridines with malononitrile in excellent yield and stereoselectivity is described. The reaction serves as a tool for the synthesis of a large variety of substituted 4, 5-dihydropyrroles ...
Fredheim S S Department of Paediatrics, Herlev Hospital, Arkaden, Turkisvej 14, DK 2730 Herlev, Denmark. - - 2013
We investigated the long-term impact of diabetic ketoacidosis (DKA) at onset on metabolic regulation and residual beta cell function in a Danish population with type 1 diabetes. The study is based on data from DanDiabKids, a Danish national diabetes register for children. The register provides clinical and biochemical data on ...
Huang Kai - - 2013
The scarcity of information on polybrominated diphenyl ethers' (PBDEs) flow in landfill restricts the life cycle analysis of PBDEs. In this study, eight PBDE congeners (BDEs 28, 47, 99, 100, 153, 154, 183, and 209) in topsoil, vegetation leaves, leachate, and municipal aged refuse collected from Shanghai Laogang Municipal Landfill ...
Ma Yaxi - - 2013
PURPOSE: The treatment of ovarian tumors is carried out with platinum medicine which can lead to incompatibilities or resistances. Thus, it is of great interest to check new medicine suitability for its application. AZD1152 is an Aurora kinase inhibitor predominantly works against Aurora kinase B involved in the chromosome segregation. ...
Gulleroglu Kaan K Department of Pediatric Nephrology, Baskent University, Ankara, - - 2013
Atypical hemolytic uremic syndrome (aHUS) is associated with defective regulation of the complement pathway. Neurological involvement is the most common extrarenal complication and represents a major cause of mortality and morbidity. Two girls aged 11 and 6 years, respectively, developed aHUS and were treated immediately with plasma exchange (PE) and fresh ...
Corradi Lara S - - 2013
The prostate comprises a glandular epithelium embedded within a fibromuscular stroma. The stroma is a complex arrangement of cells and extracellular matrix (ECM) components in addition to growth factors, regulatory molecules, remodelling enzymes, blood vessels, nerves and immune cells. The principal sources of ECM components are fibroblasts and smooth muscle ...
Ayers Katie - - 2013
BACKGROUND: Endoscopic therapy has emerged as an alternative to surgical esophagectomy for the management of Barrett's esophagus (BE)-associated neoplasia. Accurate pretreatment staging is essential to ensure an appropriate choice of therapy and optimal long-term outcomes. This study aimed to assess the frequency with which expert histopathologic review of biopsies combined ...
Helvind Neel Maria - - 2013
BACKGROUND: Robot-assisted laparoscopy has been reported to be a safe and feasible alternative to traditional laparoscopy. The aim of this study was to compare short-term results in patients with colonic cancer who underwent robot-assisted laparoscopic colonic resection (RC) or laparoscopic colonic resection (LC). METHODS: The study was a retrospective case ...
Chen Songwen - - 2013
PURPOSE: We sought to evaluate the disregarded spatial torsion of the ipsilateral superior and inferior pulmonary veins (PVs). METHODS: Forty-eight consecutive atrial fibrillation patients, with four discrete PVs, were enrolled. The ostium plane of each PV, labeled by three landmarks on the CT image, was identified by three experienced observers ...
O'Callaghan Grace - - 2013
Despite studies demonstrating that inhibition of cyclooxygenase-2 (COX-2)-derived prostaglandin E(2) (PGE(2) ) has significant chemotherapeutic benefits in vitro and in vivo, inhibition of COX enzymes is associated with serious gastrointestinal and cardiovascular side-effects, limiting the clinical utility of these drugs. PGE(2) signals through four different receptors, (EP1 -EP4), and targeting ...
Kobashi Yoshihiro - - 2013
Objective: We evaluated the clinical usefulness of glycopeptidolipid (GPL) core antigen for diagnosing Mycobacterium avium complex (MAC) pulmonary disease (MAC-PD), including patients with clinically suspected MAC-PD. Methods: GPL core antibody levels were measured in 57 patients with MAC-PD satisfying the American Thoracic Society (ATS) criteria for pulmonary disease due to ...
Mejía Natalia N Department of Medicine, University of Oviedo, C/Julián Clavería s/n, 33006 Oviedo, Spain. - - 2013
The main purpose was to build a database while facilitating access to genotyping in order to improve the clinical and molecular knowledge of primary tubulopathies. Three tertiary referral centers of Spain collect clinical data through the site http://www.renaltube.com , while offering the analysis of 22 genes corresponding to 23 primary ...
Rahnama I Mohammad S - - 2013
ABSTRACT: BACKGROUND: To investigate the effect of prostaglandin depletion by means of COX-inhibition on cholinergic enhanced spontaneous contractions. METHODS: The urethra and bladder of 9 male guinea pigs (weight 270--300 g) were removed and placed in an organ bath with Krebs' solution. A catheter was passed through the urethra through ...
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