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Results 201 - 250 of 2969
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Zhang Hongxia - - 2013
AIMS AND OBJECTIVES: To investigate the clinical characteristics of rejection after upper abdominal cluster transplantation. BACKGROUND: Abdominal organ cluster transplantation is used to treat multiple abdominal organ diseases. Delay in monitoring and treatment can lead to graft failure. DESIGN: A descriptive study. METHODS: Data collected from eight patients who underwent ...
Barhoum Suliman - - 2013
Pulsed-field-gradient nuclear magnetic resonance (PFG-NMR) is used to obtain the true hydrodynamic size of complexes of peptides with sodium dodecyl sulfate SDS micelles. The peptide used in this study is a 19-residue antimicrobial peptide, GAD-2. Two smaller dipeptides, alanine-glycine (Ala-Gly) and tyrosine-leucine (Tyr-Leu), are used for comparison. We use PFG-NMR ...
Kundu Debasree - - 2013
A novel 4-nitrotoluene-degrading bacterial strain was isolated from pesticides contaminated effluent-sediment and identified as Rhodococcus pyridinivorans NT2 based on morphological and biochemical properties and 16S rDNA sequencing. The strain NT2 degraded 4-NT (400 mg l(-1)) with rapid growth at the end of 120 h, reduced surface tension of the media from 71 to ...
Kim B-J - - 2013
Although the presence of metabolic syndrome (MetS) and increasing numbers of MetS components were associated with attenuated bone loss at various skeletal sites in postmenopausal women, this beneficial effect of MetS on bone mass can be mainly explained by higher mechanical loading in the affected subjects. INTRODUCTION: Previous cross-sectional epidemiological ...
Auner Holger W - - 2013
ABSTRACT Progression or relapse occurs in the vast majority of patients with multiple myeloma (MM) who undergo up-front autologous haematopoietic cell transplantation (AHCT1), which remains a cornerstone of treatment in the era of novel agents. Limited data are available regarding the value of salvage therapy with a second AHCT (AHCT2) ...
Hansen Hanne Demant - - 2013
Imaging the cerebral serotonin 2A (5-HT(2A) ) receptors with positron emission tomography (PET) has been carried out in humans with [(11) C]MDL 100907 and [(18) F]altanserin. Recently, the MDL 100907 analogue [(18) F]MH.MZ was developed combining the selectivity profile of MDL 100907 and the favourable radiophysical properties of fluorine-18. Here, ...
Kobayashi Ryota - - 2013
Many mechanisms of neural processing rely critically upon the synaptic connectivity between neurons. As our ability to simultaneously record from large populations of neurons expands, the ability to infer network connectivity from this data has become a major goal of computational neuroscience. To address this issue, we employed several different ...
Nahrwold Markus - - 2013
Tumor targeting anticancer drug conjugates that contain a tumor recognition motif (homing device) are of high current relevance. Cryptophycins, naturally occurring cytotoxic cyclo-depsipeptides have been modified by total synthesis to provide analogs suitable for conjugation to peptide-based homing devices. An array of functionalized β2-amino acids was synthesized and incorporated into ...
Liu Wen - - 2013
Aims and objectives.  To translate the Edinburgh Feeding Evaluation in Dementia scale (EdFED) into simplified Chinese and to comprehensively evaluate its reliability and validity. Background.  The EdFED, the only validated instrument at present for assessing feeding difficulty in older people with dementia, is available in the original English and traditional ...
Castro-Moreno Marisol - - 2013
Annona lutescens Saff. (Annonaceae) grows as a native tree in Chiapas, Mexico in Tropical Dry Forest habitat. Like most Annonaceae, it biosynthesizes benzylisoquinoline alkaloids, mostly liriodenine. To determine the influence of seasonal changes in the accumulation of liriodenine, the monthly variation of liriodenine content in roots, stems and leaves of ...
van der Aar Angelic M G - - 2013
The mechanisms preventing detrimental T-cell responses against commensal skin bacteria remain elusive. Using monocyte-derived and skin-derived dendritic cells (DCs), we demonstrate that epidermal Langerhans cells (LCs), the DCs in the most superficial layer of the skin, have a poor capacity to internalize bacteria because of low expression of FcγRIIa. Furthermore, ...
Bas-Lando Maayan - - 2013
OBJECTIVE: Varix of the fetal intra-abdominal umbilical vein (VFIUV) has been reported to be associated with an increased risk of adverse perinatal outcome and especially with intra-uterine fetal demise (IUFD). Induction of preterm birth, as early as 32-34 weeks gestation has been suggested to minimize this risk. We aimed to evaluate ...
Yu Zijun - - 2013
</sub>New imidazole based energetic molecules (1,4-dinitroimidazole, 2,4-dinitroimidazole, 1-methyl-2,4-dinitroimidazole, and 1-methyl-2,4,5-trinitroimidazole) are studied both experimentally and theoretically. The NO molecule is observed as a main decomposition product from the above nitroimidazole energetic molecules excited at three UV wavelengths (226, 236, and 248 nm). Resolved rotational spectra related to three vibronic bands ...
Johansson-Persson Anna - - 2013
PURPOSE: The aim of the study was to investigate how a diet high in dietary fiber, with several fiber sources included, modulates glucose and lipid metabolism and the inflammatory response in humans. METHODS: Subjects (n = 25) aged 58.6 (1.1) years (mean and SD) with a BMI of 26.6 (0.5) kg/m(2) and ...
Schacht Joseph P - - 2013
RATIONALE: Many studies have reported medication effects on alcohol cue-elicited brain activation or associations between such activation and subsequent drinking. However, few have combined the methodological rigor of a randomized clinical trial (RCT) with follow-up assessments to determine whether cue-elicited activation predicts relapse during treatment, the crux of alcoholism. OBJECTIVES: ...
Dhimolea Eugen - - 2013
Clinical observations suggest that pregnancy provides protection against cancer. The mechanisms involved, however, remain unclear. Fetal cells are known to enter the mother's circulation during pregnancy and establish microchimerism. We investigated if pregnancy-related embryonic/fetal stem cell integration plays a role in breast cancer. A high-sensitivity Y-chromosome assay was developed to ...
Ben Salah Afif - - 2013
There is a need for a simple and efficacious treatment for cutaneous leishmaniasis with an acceptable side-effect profile. We conducted a randomized, vehicle-controlled phase 3 trial of topical treatments containing 15% paromomycin, with and without 0.5% gentamicin, for cutaneous leishmaniasis caused by Leishmania major in Tunisia. We randomly assigned 375 ...
Wang Xiaoyu - - 2013
ABSTRACT: BACKGROUND: Binning 16S rRNA sequences into operational taxonomic units (OTUs) is an initial crucial step in analyzing large sequence datasets generated to determine microbial community compositions in various environments including that of the human gut. Various methods have been developed, but most suffer from either inaccuracies or from being ...
Zhou Jian - - 2013
Replacement of phenyl ring(s) in tetraphenylethene by naphthalene ring(s) generates a series of new luminogens with aggregation-induced emission (AIE) characteristics, demonstrating that bulky naphthalene rings can serve as a rotor to construct AIE luminogens.
Svintsova Liliya I - - 2013
The use of radiofrequency ablation (RFA) for the management of supraventricular tachycardia (SVT) in infants and small children remains controversial. The aim of this study was to evaluate the safety and efficacy of RFA in critically ill small children (<1 year of age) with drug-resistant tachycardia accompanied by arrhythmogenic cardiomyopathy and ...
Pushkar Dmitry Y - - 2013
Necrotising fasciitis is a severe form of soft tissue infection. Herein, we present an unreported complication of the transvaginal repair of a pelvic organ prolapse (POP) with trocar-guided polypropylene mesh and a concomitant hysterectomy. A 61-year-old Caucasian female who had been using an intrauterine device (IUD) for 30 years presented with ...
Jóhannesson Gauti - - 2013
Purpose:  To investigate the effects of repeated measurements of intraocular pressure (IOP) using Goldmann applanation tonometry (GAT) and applanation resonance tonometry (ART) to identify mechanisms contributing to the expected IOP reduction. Methods:  A prospective, single-centre study with six healthy volunteers. Consecutive repeated series (six measurements/serie/method) were made alternately on both ...
Hao Qingru - - 2013
New Delhi metallo-beta-lactamase-1(NDM-1)-carrying isolates, which are resistant to most clinical used antibiotics except for tigecycline and colistin, have been found worldwide. Cathelicidin-BF (BF-30) is found in the venom of the snake Bungarus fasciatus and exhibits broad antimicrobial activity. Cbf-K(16) and Cbf-A(7) A(13) were obtained by mutating Lys(16) , Ala(7) , ...
Kuo Chia-Chi - - 2013
AIMS AND OBJECTIVES: This study presents a discussion of the physiological and psychological efficacy of a self-regulation protocol in lowering acute exacerbation symptoms in patients with chronic obstructive pulmonary disease. BACKGROUND: Patients with chronic obstructive pulmonary disease are often troubled by acute exacerbation and must learn how to prevent this. ...
Yin Xingbin - - 2013
A highly sensitive, rapid assay method has been developed and validated for the analysis of hyperoside in beagle dog plasma with liquid chromatography coupled to tandem mass spectrometry with electrospray ionization in the positive-ion mode. The assay procedure involves extraction of hyperoside and ginsenoside Re (IS) from beagle dog plasma. ...
Mistlberger Günter - - 2013
Photoresponsive ion extraction/release systems (PRIONERS) represent a highly interesting tool for the localized and time controlled chemical perturbation of biological materials. We report here on our first results on phototriggered calcium and sodium exchanging materials. Such materials exist in two distinct states ('on' and 'off'), depending on the wavelength of ...
PiÄ…tosa Barbara - - 2013
Common variable immune deficiency (CVID) is a heterogeneous disease associated with ineffective production of antibodies. It is usually diagnosed in adulthood, but a variable proportion of children develop CVID. Early identification of patients with potentially worse prognosis may help to avoid serious complications. The goal of this study was to ...
Williams Emily D - - 2013
BACKGROUND: The evidence supporting a relationship between stress and diabetes has been inconsistent. PURPOSE: This study examined the effects of stress on abnormal glucose metabolism, using a population-based sample of 3,759, with normoglycemia at baseline, from the Australian Diabetes, Obesity and Lifestyle study. METHODS: Perceived stress and stressful life events ...
Pelavski A D - - 2013
OBJECTIVES: To characterise transfusion and determine its main predictors in nonagenarians undergoing non-elective, non-traumatic surgery. Simultaneously, we compared nonagenarians to a similar, but younger sample, as far as the transfusional policy is concerned. BACKGROUND: Perioperative anaemia and transfusion are currently topical, but little is known about them in this population. ...
Skliris Antonis - - 2013
Serglycin (SG) is mainly expressed by hematopoetic cells as an intracellular proteoglycan. Multiple myeloma cells constitutively secrete SG, which in some cell lines is also localized on cell surface. In this study, isolated SG from myeloma cells was found to interact with collagen type I (Col I), which is a ...
Caraty A - - 2013
Recent studies demonstrated that kisspeptin (Kp) administration, given as a slow constant infusion of Kp10 (the shortest endogenous form of the kp molecules which carries biological activity), is able to stimulate gonadotrophin secretion and induce ovulation in anoestrus acyclic ewes. Detailed analysis of peripheral luteinising hormone (LH) concentrations, obtained at ...
Vasconcelos Helena - - 2013
PURPOSE: To evaluate morphological and functional chorioretinal changes 5 years after standard photodynamic therapy (PDT) for chronic central serous chorioretinopathy (CSC). METHODS: A retrospective, nonrandomized study, including patients with chronic CSC treated with standard PDT and followed for at least 60 months. All patients underwent a complete ophthalmological examination, and the location ...
Downs Gregory S - - 2013
Here we present a genome-wide overview of transcriptional circuits in the agriculturally significant crop species Zea mays. We examined transcript abundance data at 50 developmental stages, from embryogenesis to senescence, for 34,876 gene models and classified genes into 24 robust coexpression modules. Modules were strongly associated with tissue types and ...
Scapicchio Pier Luigi - - 2013
Abstract Choline alphoscerate (alpha-GPC) is a semisynthetic derivative of phosphatidylcholine with central parasympathomimetic action. This action is at the basis of its use in pathologies characterized by cognitive deficits of neurodegenerative or vascular nature. In a number of clinical studies alpha-GPC demonstrated benefit in patients with cognitive dysfunction. In light ...
Hammond Ashley S - - 2013
Hip joint diameter is highly correlated with body size in primates and so can potentially provide important information about the biology of fossil hominins. However, quantifying hip joint size has been difficult or impossible for many important but fragmentary specimens. New three-dimensional technologies can be used to digitally fit spheres ...
Deguchi Ayumi - - 2013
Black color in flowers is a highly attractive trait in the floricultural industry, but its underlying mechanisms are largely unknown. This study was performed to identify the bases of the high accumulation of anthocyanidins in black cultivars and to determine whether the high accumulation of total anthocyanidins alone leads to ...
Chan Yap-Hang - - 2013
PURPOSE: Epidemiological studies showed that PR prolongation is associated with increased risk of adverse cardiovascular outcomes. We investigated the relations of PR interval with indices of vascular function and endothelial repair as the underlying mechanisms. METHODS: The study comprised 348 high-risk patients with prior coronary artery disease, ischemic stroke, and/or ...
Galitski Victor - - 2013
Spin-orbit coupling links a particle's velocity to its quantum-mechanical spin, and is essential in numerous condensed matter phenomena, including topological insulators and Majorana fermions. In solid-state materials, spin-orbit coupling originates from the movement of electrons in a crystal's intrinsic electric field, which is uniquely prescribed in any given material. In ...
Furuyama Kazuto - - 2013
The presence of epidermal growth factor receptor (EGFR) somatic mutations in non-small cell lung cancer patients is associated with response to treatment with EGFR-tyrosine kinase inhibitors (EGFR-TKIs), such as gefitinib and erlotinib. More than one hundred mutations in the kinase domain of EGFR have been identified. In particular there are ...
Pathak Khyati V - - 2013
AIMS: 1) To characterize fungal antagonistic bacilli isolated from aerial roots of banyan tree and identify the metabolites responsible for their antifungal activity. METHODS AND RESULTS: Seven gram positive endospore forming rod shaped endophytic bacterial strains exhibiting a broad spectrum antifungal activity were isolated from the surface sterilized aerial roots ...
Subotić S - - 2013
Pikeperch (Sander lucioperca), European catfish (Silurus glanis), common carp (Cyprinus carpio), and gobies (Neogobius gymnotrachelus, Neogobius melanostomus) were collected from the Danube River (Belgrade section), and samples of liver, muscle, or whole-body composites (in the case of gobies) were analyzed for As, Cu, Fe, Hg, Mn, and Zn with inductively ...
Tusman Gerardo - - 2013
The aim of this study was to determine typical values for non-invasive volumetric capnography (VCap) parameters for healthy volunteers and anesthetized individuals. VCap was obtained by a capnograph connected to the airway opening. We prospectively studied 33 healthy volunteers 32 ± 6 years of age weighing 70 ± 13 kg at a height of 171 ± 11 cm in ...
Seguin Brian - - 2013
The Canham-Helfrich free-energy density for a lipid bilayer has drawn considerable attention. Aside from the mean and Gaussian curvatures, this free-energy density involves a spontaneous mean-curvature that encompasses information regarding the preferred, natural shape of the lipid bilayer. We use a straightforward microphysical argument to derive the Canham-Helfrich free-energy density. ...
Kong Yuhan - - 2013
Whether ischemic postconditioning (IPC) can significantly alleviate ischemic injury hinges on the appropriate measure. In this study, the expression RGMa and IL-1β, IL-6 are investigated to estimate the therapeutic benefits of various postconditioning strategies after cerebral ischemia/reperfusion. The study consists of the sham-operated group and five treatment groups: ischemia/reperfusion (I/R), ...
Sonay Ali Yasin - - 2013
Assembly into higher-order structures is very important to fully benefit from the extraordinary properties of nanomaterials. SWCNTs are assembled into nanorings using DNA hybridization. The oligonucleotides are covalently attached to the SWCNTs and an oligonucleotide complementary to the oligonucleotides covalently bound to SWCNTs is used to bring assemble them by ...
Zeng Rui-Chao - - 2013
The present study was to evaluate the value of miRNA-30a in plasma as potential tumor marker in detecting breast cancer (BC). Using a novel approach to extract miRNA-30a from the plasma followed by real-time quantitative polymerase chain reaction (RQ-PCR) analysis, levels of miRNA-30a were quantified in plasma specimens of 100 ...
Raghavan Sheila - - 2013
Objective To examine the efficacy, acceptability and feasibility of early medical abortion, with the option of home administration of misoprostol, in Uzbekistan. Methods A total of 450 women were enrolled at national, municipal and private facilities in Tashkent, Uzbekistan. Women who presented for termination of pregnancy with gestations up to ...
Edison Erica E - - 2013
Creatine is essential for normal neural development; children with inborn errors of creatine synthesis or transport exhibit neurological symptoms such as mental retardation, speech delay and epilepsy. Creatine accretion may occur through dietary intake or de novo creatine synthesis. The objective of the present study was to determine how much ...
Galdiero Stefania - - 2013
Herpes simplex virus (HSV) is a significant human pathogen causing mucocutaneous lesions primarily in the oral or genital mucosa. Although acyclovir (ACV) and related nucleoside analogs provide successful treatment, HSV remains highly prevalent worldwide and is a major cofactor for the spread of human immunodeficiency virus. Encephalitis, meningitis, and blinding ...
Murphy Jane L - - 2013
AIMS AND OBJECTIVES: To examine current guidelines and the evidence base to illustrate the importance of nutrition, diet and lifestyle advice to support people who have survived cancer and help them integrate back into normal life, improve their quality of life and potentially improve their chance of long-term survival. BACKGROUND: ...
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