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Barnette Lashonda - - 2013
There are many creative ways to teach arterial blood gas interpretation. This article illustrates the use of the stepwise approach, tables, figures, case studies, illustrations, computer-based learning modules, and the tic-tac-toe approach. The authors recommend making several approaches available so students and new critical care nurses can choose the ones ...
Lee Cara Beth - - 2013
: Acetabular dysplasia is a common cause of hip pain that can lead to premature osteoarthritis. This study explores whether demographic characteristics of patients diagnosed with acetabular dysplasia in adolescence and adulthood [adult-diagnosed dysplasia (AD)] differ from those who are diagnosed with developmental dysplasia of the hip (DDH) in infancy. ...
Rassin Michal - - 2013
As many as 5% of male hospital patients develop pressure ulcers. This brief study was done to obtain more research about this topic by evaluating the effectiveness of an intervention designed to prevent pressure ulcers in the urinary meatus as a result of urethral catheterization. Implications for critical care nurses ...
Erickson Jodi - - 2013
Bedside nurses in the critical care setting deal with death on a regular basis. Historically, end-of-life decision making has been addressed by physicians with the family and patient, yet nurses may be a better resource for families during the decision-making process. The purpose of this article was to provide a ...
Leff Stephen S - - 2013
Peer aggression and bullying is of considerable importance given the large number of youth involved with or witnesses to this behavior and the association with maladjustment and other negative outcomes. This article reviews current literature on aggression and bullying among school-age youth, including subtypes and differentiating between aggression and bullying. ...
James Jeremy R - - 2013
: Recent publications show a high rate of hypovitaminosis D among children in general as well as among children with fractures. 25-hydroxyvitamin D levels were analyzed from hospital records to determine the prevalence of hypovitaminosis D, with the goal of using that information in fracture management and nutritional counseling. : ...
Ruiz-Ruiz Susana - - 2013
Citrus tristeza virus (CTV) encodes a singular protein (p23, 209 amino acids) with multiple functions, including RNA silencing suppression (RSS). Confocal laser-scanning microscopy of green fluorescent protein (GFP)-p23 agroexpressed in Nicotiana benthamiana revealed its accumulation in the nucleolus, Cajal bodies, and plasmodesmata. To dissect the nucleolar localization signal (NoLS) typically ...
Wong Sunny H - - 2013
Inflammatory bowel diseases occur due to an aberrant immune response to luminal antigens in genetically predisposed individuals. Although specific genetic loci have been identified underlying the predisposition, they have not fully explained the disease etiology. Striking epidemiological observations implicate the critical role of environmental influences on disease penetrance. The emergence ...
Kabirian Nima - - 2013
: Conradi-Hunermann syndrome (CHS) is a rare metabolic syndrome with several orthopaedic problems. Early-onset scoliosis is of great importance because of often rapidly progressive nature and high risk of postoperative complications. : To report the 34-year follow-up and outcome of a patient with CHS treated with combined anterior and posterior ...
Mallet Cindy - - 2013
: Many commissural reconstruction techniques have been described for the treatment of syndactyly. This study is the first to compare long-term results of 2 commissural dorsal flap procedures (T-flap and omega-flap). : Fifty-nine web-spaces in 39 patients, operated on between 1991 and 2008, were retrospectively analyzed. Thirty-six T-flap and 23 ...
Gray Frances C - - 2013
PURPOSE/OBJECTIVES:: This is a report of the results of a pilot project conducted to identify the areas where role confusion/ambiguity exists in the practice of nurse case management. METHODOLOGY AND SAMPLE:: A convenience sample of 25 registered nurses practicing as case managers in a small east coast medical treatment facility's ...
Bono Kenneth T - - 2013
: Slipped capital femoral epiphysis (SCFE) is usually treated with percutaneous in situ screw fixation to prevent further progression of deformity. The purpose of this investigation is to compare computer navigation (CN) techniques with traditional fluoroscopic (fluoro) techniques for in situ fixation of SCFE. : This study was an IRB-approved ...
Schallom Marilyn - - 2013
Gastroesophageal reflux (GER) is a common occurrence in critically ill, mechanically ventilated patients. Reflux can lead to pulmonary aspiration of gastric contents and subsequent pneumonia. Several characteristics of patients, interventions provided in the intensive care unit setting, and factors associated with feeding increase a patient's risk for reflux. Critical care ...
Chung Moon Sang - - 2013
: Polydactyly is one of the most common congenital differences that affect the hand. It has various anatomic and morphologic features. Although the Wassel classification has been used widely for radial polydactyly, it is based on the anatomic level of duplication and has some limitations in describing the concrete morphology ...
Shukla Pinak Y - - 2013
: Unilateral hip reconstruction in patients with cerebral palsy can be complicated by contralateral subluxation and ipsilateral failure. We sought to identify predictors for failure after unilateral reconstruction in patients with GMFCS IV-V CP with unilateral hip involvement. : We performed an IRB-approved retrospective study on GMFCS IV-V CP patients ...
Bledsoe Marlyn K - - 2013
: Historically, physicians completed status assignment during the admission process. Incorrect status assignment of patients can result in reimbursement problems and denial of payment by Medicare, Medicaid, and private insurance companies. : The purpose of this study was to evaluate the impact of case manager's role with status assignment during ...
Lykissas Marios G - - 2013
: Melnick-Needles syndrome (MNS) is a rare X-linked dominant disorder affecting the skeletal system and connective tissue. To date, <70 cases with MNS have been documented. Although few reports in the literature have shown that these patients might develop kyphoscoliosis, there is no report regarding long-term follow-up of patients with ...
Seemüller Erich - - 2013
Previous examination revealed a correlation of phytopathogenic data of 'Candidatus Phytoplasma mali' strains and the DNA sequence variability of a type ATP00464 hflB gene fragment. To further investigate such a relationship, all distinct genes previously annotated as hflB in the genome of 'Ca. P. mali' strain AT were fully sequenced ...
Harbaugh Calista M - - 2013
Alvimopan was approved by the Food and Drug Administration in May 2008 and has been shown to accelerate gastrointestinal recovery after colectomy. Our independent study evaluated alvimopan as it is used in actual hospital practice in the state of Michigan. We hypothesized that alvimopan significantly decreases incidence of prolonged ileus ...
Melmed Gil Y - - 2013
Variation in adherence to management guidelines for inflammatory bowel disease (IBD) suggests variable quality of care. Quality indicators (QIs) can be developed to measure the structure, processes, and outcomes of health care delivery. The RAND/UCLA appropriateness method was used to develop a set of process and outcome QIs to define ...
Tetrault Jeanette M JM Section of General Internal Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA. - - 2013
Antiretroviral (ARV) resistance is of concern. Opioid agonist treatment (ie, methadone or buprenorphine) is effective and decreases HIV transmission risk behaviors and HIV seroconversion. Despite prevention efforts, injection drug use (IDU) and risky sexual behaviors remain prevalent in patients receiving opioid agonist treatment. The purpose of this study is to ...
Kraning-Rush Casey M CM Department of Biomedical Engineering, Cornell University, 526 Campus Rd., Ithaca, NY 14853, - - 2013
While the mechanisms employed by metastatic cancer cells to migrate remain poorly understood, it has been widely accepted that metastatic cancer cells can invade the tumor stroma by degrading the extracellular matrix (ECM) with matrix metalloproteinases (MMPs). Although MMP inhibitors showed early promise in preventing metastasis in animal models, they ...
Zendejas Benjamin B Department of Surgery, Mayo Clinic, Rochester, MN 55905, - - 2013
To determine age- and sex-specific incidence rates of inguinal hernia repairs (IHR) in a well-defined US population and examine trends over time. IHR represent a substantial burden to the US healthcare system. An up-to-date appraisal will identify future healthcare needs. A retrospective review of all IHR performed on adult residents ...
Pekow Joel J Section of Gastroenterology, Hepatology, and Nutrition, University of Chicago, Chicago, Illinois, USA. - - 2013
Individuals with ulcerative colitis (UC) are at increased risk for colorectal cancer. The standard method of surveillance for neoplasia in UC by colonoscopy is invasive and can miss flat lesions. We sought to identify a gene expression signature in nondysplastic mucosa without active inflammation that could serve as a marker ...
Zhou Huan-Xiang HX Department of Physics, Florida State University, Tallahassee, Florida 32306, - - 2013
The M2 protein, a proton channel, from Influenza A has been structurally characterized by X-ray diffraction and by solution and solid-state NMR spectroscopy in a variety of membrane mimetic environments. These structures show substantial backbone differences even though they all present a left-handed tetrameric helical bundle for the transmembrane domain. ...
Gardner Brooke M BM Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, California 94158, - - 2013
Secretory and transmembrane proteins enter the endoplasmic reticulum (ER) as unfolded proteins and exit as either folded proteins in transit to their target organelles or as misfolded proteins targeted for degradation. The unfolded protein response (UPR) maintains the protein-folding homeostasis within the ER, ensuring that the protein-folding capacity of the ...
Bewtra Meenakshi M Division of Gastroenterology and Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA. - - 2013
Evidence regarding all-cause and cause-specific mortality in inflammatory bowel disease (IBD) is conflicting, and debate exists over appropriate study design to examine these important outcomes. We conducted a comprehensive meta-analysis of all-cause and cause-specific mortality in both Crohn's disease (CD) and ulcerative colitis (UC), and additionally examined various effects of ...
Berry Joel D JD Center for Phage Technology, Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, - - 2013
The λ Rz and Rz1 proteins are the subunits of the spanin complex, required for the disruption of the outer membrane during host lysis. Rz, the inner membrane or i-spanin, has a largely alpha-helical periplasmic domain, whereas Rz1, the outer membrane or o-spanin, has a 25% proline content with no ...
Vincent Ludovic G LG Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, - - 2013
Mesenchymal stem cells (MSCs) respond to the elasticity of their environment, which varies between and within tissues. Stiffness gradients within tissues can result from pathological conditions, but also occur through normal variation, such as in muscle. MSC migration can be directed by shallow stiffness gradients before differentiating. Gradients with fine ...
Chen Jieming J Integrated Graduate Program in Physical and Engineering Biology, Yale University, New Haven, Connecticut 06520, - - 2013
Protein-protein interactions play key roles in many cellular processes and their affinities and specificities are finely tuned to the functions they perform. Here, we present a study on the relationship between binding affinity and the size and chemical nature of protein-protein interfaces. Our analysis focuses on heterodimers and includes curated ...
Slingsby Christine C Department of Biological Sciences, Crystallography, Institute of Structural and Molecular Biology, Birkbeck College, Malet Street, London WC1E 7HX, United Kingdom. - - 2013
The camera eye lens of vertebrates is a classic example of the re-engineering of existing protein components to fashion a new device. The bulk of the lens is formed from proteins belonging to two superfamilies, the α-crystallins and the βγ-crystallins. Tracing their ancestry may throw light on the origin of ...
Akkaladevi N N Department of Biochemistry, University of Kansas Medical Center, Kansas City, Kansas, - - 2013
We have devised a procedure to incorporate the anthrax protective antigen (PA) pore complexed with the N-terminal domain of anthrax lethal factor (LFN ) into lipid nanodiscs and analyzed the resulting complexes by negative-stain electron microscopy. Insertion into nanodiscs was performed without relying on primary and secondary detergent screens. The ...
Berglund E Carina EC Department of Molecular Biology and Chemistry, Analytical Chemistry, University of Gothenburg, Kemivägen 10, SE-412 96 Gothenburg, - - 2013
Micellar electrokinetic capillary chromatography with electrochemical detection has been used to quantify biogenic amines in freeze-dried brains of Drosophila melanogaster. Freeze-drying samples offers a way to preserve the biological sample while making dissection of these tiny samples easier and faster. Fly samples were extracted in cold acetone and dried in ...
Abe Masahiro M Department of Protein Structure, Function and Design, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, - - 2013
Sugars, which function as osmolytes within cells, retard the amyloid fibril formation of the amyloidosis peptides and proteins. To examine the mechanism of this retardation in detail, we analyzed the effect of sugars (trehalose, sucrose, and glucose) on the polypeptide chains in 3Hmut Wil, which is formed by the mutation ...
Guo Yudi Y Department of Chemistry, School of Science, Harbin Institute of Technology, Harbin 150001, - - 2013
We describe a controllable method to fabricate hexagonally close-packed Langmuir-Blodgett (LB) monolayers with stearic acid (SA) as co-surfactant and methanol as co-solvent. The optimal SA concentrations and volume ratios of chloroform to methanol are 0.8 mg/mL and 3:1 for particles of 140 nm, 0.50 mg/mL and 4:1 for particles of ...
Liu Ce Feng CF Department of Chemistry and Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, Massachusetts 02454, - - 2013
Autoinducer inactivator A (AiiA) is a metal-dependent N-acyl homoserine lactone hydrolase that displays broad substrate specificity but shows a preference for substrates with long N-acyl substitutions. Previously, crystal structures of AiiA in complex with the ring-opened product N-hexanoyl-l-homoserine revealed binding interactions near the metal center but did not identify a ...
Ekkebus Reggy R Division of Cell Biology, The Netherlands Cancer Institute, Amsterdam, The - - 2013
Active-site directed probes are powerful in studies of enzymatic function. We report an active-site directed probe based on a warhead so far considered unreactive. By replacing the C-terminal carboxylate of ubiquitin (Ub) with an alkyne functionality, a selective reaction with the active-site cysteine residue of de-ubiquitinating enzymes was observed. The ...
Wold Judith Lupo - - 2013
This article describes a formal nurse educator train-the-trainer program initiated to educate qualified health professionals to teach contemporary nursing continuing education in the country of Georgia, formerly part of the Soviet Union. A 3-month intensive train-the-trainer program model was used to educate potential nurse educators to provide a foundation for ...
Guan Zhen-Hua - - 2013
We investigated the structure and seasonality of the proximity network in a group of polygynous western black crested gibbons (Nomascus concolor) using social network analysis. The spatial proximity changed seasonally and was affected by temperature and rainfall. Preferred proximity association was not distributed randomly among individuals. Kinship was one explanation ...
Yürekli Vedat Ali - - 2013
It is well known that oxidative stress plays an important role in the etiology of epilepsy. We investigated effects of selenium (Se) and topiramate (TPM) combination supplementation on antioxidant and oxidant values in control and patients with epilepsy and refractory epilepsy. For the aim, we used control (n = 19), epilepsy + ...
Schott M - - 2013
Thyrotoxicosis is mainly caused by autonomous adenomas of the thyroid gland and by Graves' disease. A less frequent cause for thyrotoxicosis is Hashimoto's thyroiditis. Thyrotoxicosis in autonomous adenomas and Graves' disease is caused by an increased thyroid hormone production whereas hyperthyroidism in Hashimoto's thyroiditis results from destruction of the thyroid ...
Luo Ying - - 2013
This study aimed to discuss the energy budget of Elliot's pheasant Syrmaticus ellioti in different seasons, with life and health, good growth and normal digestion of Elliot's pheasant as the tested objects, The energy budget of Elliot's pheasant was measured by daily collection of the trial pheasants' excrement in the ...
- - 2013
During November 24-27, 2012, the Arizona Department of Health Services (ADHS) was notified that eight male inmates of prison A, a maximum security prison, had been hospitalized for treatment of an acute neurologic condition suspected to be botulism. Botulism is a serious paralytic illness caused by a nerve toxin produced ...
Foster Kim N - - 2013
BACKGROUND:Physical and mental health problems are interconnected, and registered nurses need to be competent in performing comprehensive physical and mental health assessment. This article reports on a pilot evaluation of education in comprehensive health assessment and clinical judgment for registered nurses enrolled in a master of nursing program. METHODS:Observation and ...
Wang Guanghuan - - 2013
We aimed to explore the association of blood Zn, Fe, and Cu concentrations and changes in the pediatric risk of mortality (PRISM) score in critically ill children, to predict prognosis. We included 31 children (22 boys and 9 girls, 1 month to 5 years old), who had been admitted to the intensive ...
Zhang Ming-Ming - - 2013
Although differences in food-hoarding tactics both reflect a behavioral response to cache pilferage among rodent species and may help explain their coexistence, differentiation in cache pilfering abilities among sympatric rodents with different hoarding strategies is seldom addressed. We carried out semi-natural enclosure experiments to investigate seed hoarding tactics among three ...
Malaguarnera Michele - - 2013
Hepatic encephalopathy is a common complication of hepatic cirrhosis. The clinical diagnosis is based on two concurrent types of symptoms: impaired mental status and impaired neuromotor function. Impaired mental status is characterized by deterioration in mental status with psychomotor dysfunction, impaired memory, and increased reaction time, sensory abnormalities, poor concentration, ...
Gonçalves Susana - - 2013
Alpha-synuclein (aSyn) is implicated in Parkinson's disease and several other neurodegenerative disorders. To date, the function and intracellular dynamics of aSyn are still unclear. Here, we tracked the dynamics of aSyn using photoactivatable green fluorescent protein as a reporter. We found that the availability of the aSyn N terminus modulates ...
Fan Yao-Dong - - 2013
Association between the reward caused by consuming drugs and the context in which they are consumed is essential in the formation of morphine-induced conditioned place preference (CPP). Glucocorticoid receptor (GRs) activation in different regions of the brain affects reward-based reinforcement and memory processing. A wide array of studies have demonstrated ...
- - 2013
Background: Cigarette smoking remains the leading cause of preventable morbidity and mortality in the United States. Despite overall declines in cigarette smoking, a high prevalence of smoking persists among certain subpopulations, including persons with mental illness. Methods: Combined data from the 2009-2011 National Survey on Drug Use and Health (NSDUH) ...
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