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de Oliveira Paulo R N - - 2013
The cytotoxic activity of crude extracts and their fractions from leaves and roots of G. pohliana was assessed against nine human cancer cell lines: melanoma (UACC-62), breast (MCF-7), breast expressing the multidrug resistance phenotype (NCI-ADR), lung (NCI-460), prostate (PCO-3), kidney (786-0), ovarian (OVCAR), colon (HT-29) and leukaemia (K-562). The hexane ...
Chu Fong Lam - - 2013
To facilitate the detection of acrylamide or styrene adduct of amino acids by mass spectrometry based techniques, phenylalanine was used as a representative amino acid and pyrolysis was employed in conjunction with isotope labeling technique as a micro-scale sample preparation tool to generate the reaction products. The residues remaining after ...
Kalayciyan Raffi - - 2013
PURPOSE: To develop a sodium-MRI ((23) Na-MRI) method for bilateral renal sodium concentration (RSC) measurements in rat kidneys at 9.4 Tesla (T). MATERIALS AND METHODS: To simultaneously achieve high B(1) -field homogeneity and high receive sensitivity a dual resonator system composed of a double-tuned linearly polarized (1) H/(23) Na volume ...
Shin Jaemin - - 2013
PURPOSE: To develop an improved and generalized technique for correcting T1-related signal fluctuations (T1 effect) in cardiac-gated functional magnetie resonance imaging (fMRI) data with flip angle estimation. THEORY AND METHODS: Spatial maps of flip angle and T1 are jointly estimated from cardiac-gated time series using a Kalman filter. These maps ...
Courivaud Cécile - - 2013
BACKGROUND: Fractalkine (CX3CL1) and its receptor (CX3CR1) are involved in antitumor immunity. Two common single nucleotide polymorphisms of the CX3CR1 gene, V249I and T280M, have been associated with reduced fractalkine signaling characterized by decreased adhesive function, signaling, and chemotaxis of leukocytes. We hypothesized that a renal transplant recipient (RTR) carrying ...
Fabricant Peter D - - 2013
Subtle variations in acetabular morphology have been implicated in several pathologic hip conditions. Although it is understood that the acetabulum forms at the junction of the ilium, ischium, and pubis at the triradiate cartilage, the ossification and development pattern of the posterior wall of the acetabulum is unknown. Standard radiographs ...
Wachira Benjamin W - - 2013
Kenya's major incidents profile is dominated by droughts, floods, fires, terrorism, poisoning, collapsed buildings, accidents in the transport sector and disease/epidemics. With no integrated emergency services and a lack of resources, many incidents in Kenya escalate to such an extent that they become major incidents. Lack of specific training of ...
Maffulli Nicola - - 2013
BACKGROUND:Lateral ankle sprains may result in pain and disability in the short term, decreased sport activity and early retirement from sports in the mid term, and secondary injuries and development of early osteoarthritis to the ankle in the long term. HYPOTHESIS:This combined approach to chronic lateral instability and intra-articular lesions ...
Trescher K - - 2013
Aim: The aim of this paper was to improve operative outcome during open-heart surgery in patients with failing hearts, the composition of cardioplegic solutions has to be further optimized. HTK-N46b, a novel cardioplegic solution, has been developed for efficient protection of the energy state of myocytes as well as endothelial ...
Ogiyama Yoshiaki - - 2013
INTRODUCTION: We have reported that the circadian rhythm of urinary potassium excretion (U(K)V) is determined by the rhythm of urinary sodium excretion (U(Na)V) in patients with chronic kidney disease (CKD). We also reported that treatment with an angiotensin receptor blocker (ARB) increased the U(Na)V during the daytime, and restored the ...
Pelaez Mireia - - 2013
AIMS: To investigate the effect of pelvic floor muscle training (PFMT) taught in a general exercise class during pregnancy on the prevention of urinary incontinence (UI) in nulliparous continent pregnant women. METHODS: This was a unicenter two armed randomized controlled trial. One hundred sixty-nine women were randomized by a central ...
McEwan Phil - - 2013
Background: Recent U.S guidelines recommend one-time birth-cohort (BC) testing for hepatitis C infection in those born from 1945 to 1965; this represents a major public health policy undertaking. The purpose of this study was to assess the role of treatment timing and prioritisation on predicted cost-effectiveness (CE). Methods: The MONARCH ...
Lip Gregory Y H - - 2013
BACKGROUND: -The impact of apixaban versus aspirin on ischaemic stroke and major bleeding in relation to the CHADS(2) and CHA(2)DS(2)-VASc stroke risk scores in atrial fibrillation(AF) has not been investigated. METHODS AND RESULTS: -In this secondary analysis of the AVERROES trial, our principal objective was to assess the effect of ...
Sharma Samir D - - 2013
PURPOSE: To develop a T2*-compensated parallel imaging and compressed sensing framework for water-fat separation, and to demonstrate accelerated quantitative imaging of proton density fat fraction. MATERIALS AND METHODS: The proposed method extends a previously developed framework for water-fat separation by additionally compensating for T2* decay. A two-stage estimation was formulated ...
Feng Jiuju - - 2013
In this work, we developed a low-cost, facile, sensitive, and selective colorimetric method for the quantitative determination of dopamine, based on 4-amino-3-hydrazino-5-mercapto-1,2,4-triazol (AHMT) functionalized gold nanoparticles (AHMP-AuNPs) as a model probe. Dopamine could induce the aggregation of the AHMT-AuNPs through hydrogen- bonding interactions, which caused the colloidal solution changed from ...
Beitsch Leslie M - - 2013
CONTEXT:: The Multi-State Learning Collaborative: Lead States in Public Health Quality Improvement (MLC) brought state and local health departments in 16 states together with public health system and national partners to prepare for national voluntary accreditation and to implement quality improvement (QI) practices. OBJECTIVE:: The MLC has collected the single ...
Saifudin Azis - - 2013
Four new germacranes [heyneanones A-D (1-4)], three new guaianes [4,10-epizedoarondiol (5), 15-hydroxyprocurcumenol (6), 12-hydroxycurcumenol (7)], and two new spirolactones [curcumanolides C (8) and D (9)] were isolated from the rhizomes of Curcuma heyneana together with 13 known sesquiterpenes and two known labdane-type diterpenes. Among the isolated compounds, heyneanone A (1), ...
Kim M - - 2013
BACKGROUND/OBJECTIVE:We aimed to examine the accuracy of segmental multi-frequency bioelectrical impedance analysis (SMF-BIA) for the assessment of whole-body and appendicular fat mass (FM) and lean soft tissue mass (LM) in frail older women, using dual-energy X-ray absorptiometry (DXA) as a reference method.SUBJECTS/METHODS:All 129 community-dwelling Japanese frail older women with a ...
Ordonez Felipe - - 2013
BACKGROUND: Small bowel transplantation has now become a recognized treatment of irreversible, permanent, and subtotal intestinal failure. OBJECTIVE: The aim of this study was to assess intestinal absorption at the time of weaning from parenteral nutrition in a series of children after intestinal transplantation. DESIGN: Twenty-four children (age range: 14-115 ...
Lin A - - 2013
BACKGROUND: Individuals at ultra-high risk (UHR) for psychosis show reduced neurocognitive performance across domains but it is unclear which reductions are associated with transition to frank psychosis. The aim of this study was to investigate differences in baseline neurocognitive performance between UHR participants with (UHR-P) and without transition to psychosis ...
Knopman David S - - 2013
Persons with mild cognitive impairment (MCI) have overt changes in thinking and memory, but they are still largely independent in daily affairs. They have a far higher rate of developing dementia (progressing to a more debilitating state of cognitive impairment) than cognitively normal persons, but at the individual patient level, ...
Korja M - - 2013
Apolipoprotein E plays an important role in neurodegenerative processes in adulthood, whereas its neurodevelopmental role is uncertain. We aimed to study the effect of apolipoprotein E on neurodevelopment in a cohort liable to neurodevelopmental changes. The cohort consisted of very preterm (< 32 gestational weeks) and/or very low birth weight ...
Leyton Cristian E - - 2013
OBJECTIVE: To track cognitive and language changes over time in patients with logopenic (lv-PPA) and semantic (sv-PPA) variants of primary progressive aphasia (PPA). METHODS: Thirteen consecutive patients with lv-PPA and 11 patients with sv-PPA underwent yearly evaluation for a mean of 3 years. Nineteen patients (11 lv-PPA, 8 sv-PPA) had ...
Soyer Philippe - - 2013
Background: Because of an expanded role for CT in the evaluation of patients with acute abdominal pain, it is not rare that acute cholecystitis is depicted by CT. However, the sensitivity and the specificity of a given CT variable for the diagnosis of acute cholecystitis is not known.Purpose: To quantitatively ...
Wada Keiko - - 2013
The effects of soy or isoflavone intake on breast cancer need to be examined further in epidemiologic studies. We assessed the associations of soy and isoflavone intake with breast cancer incidence in a population-based prospective cohort study in Japan. Participants were members from the Takayama study, aged 35 years or ...
Ghulman Motaz Ahmed - - 2013
Purpose: The aim of this study was to evaluate and compare the total color difference (ΔE) between natural teeth and fabricated crowns from three ceramic systems with different thicknesses. Materials and Methods: The color of ninety maxillary central incisors was measured from the middle third of the labial surface with ...
Bhattacharjee Sandipan - - 2013
BACKGROUND: Antidepressant use has been linked to new-onset diabetes. However, the existing literature on this relationship has yielded inconsistent findings. The primary objective of this study was to systematically synthesize the literature on the relationship between antidepressant use and new-onset diabetes using meta-analysis. METHODS: A systematic literature search was conducted ...
Agarwala Prachi - - 2013
Transforming Growth Factor β2 (TGFβ2) is a versatile cytokine with prominent role in cell migration, invasion, cellular development and immunomodulation. TGFβ2 promotes the malignancy of tumors by inducing epithelial-mesenchymal transition (EMT), angiogenesis and immunosuppression. As it is well documented that nucleic acid secondary structure can regulate gene expression, we assessed ...
Cason Garrick W - - 2013
Symptomatic adjacent-level disease after cervical fusion has led to the development and testing of several disc-replacement prostheses.Randomized controlled trials of cervical disc replacement (CDR) compared with anterior cervical discectomy and fusion (ACDF) have demonstrated at least equivalent clinical results for CDR with similar or lower complication rates.Biomechanical, kinematic, and radiographic ...
Dalili Mohammad - - 2013
Vascular stricture is a known complication of radiofrequency ablation. We used this potential of radiofrequency for voluntary restriction and closure of a pulmonary artery branch in a sheep.
Fernandez Monica A - - 2013
Purpose: A precise transfer of the position and orientation of the antirotational mechanism of an implant to the working cast is particularly important to achieve optimal fit of the final restoration. This study evaluated and compared the accuracy of metal and plastic impression copings for use in a full-arch mandibular ...
Piastowska-Ciesielska Agnieszka Wanda - - 2013
INTRODUCTION: Angiotensin II is an effector peptide showing multiple physiological effects, such as regulation of vascular tone, tissue growth and remodelling. Postlactational involution of mammary gland involves changes such as high matrix metalloproteinase activity and release of bioactive fragments of fibronectin and laminin, which may be directly regulated by angiotensin ...
Bjørk Ida Torunn - - 2013
AIM: To present a case of knowledge translation in nursing education and practice and discusses mechanisms relevant to bringing knowledge into action. BACKGROUND: The process of knowledge translation aspires to close the gap between theory and practice. Knowledge translation is a cyclic process involving both the creation and application of ...
Di Ieva Antonio - - 2013
The monitoring of intracranial pressure (ICP) is an important tool in medicine for its ability to portray the brain's compliance status. The bedside monitor displays the ICP waveform and intermittent mean values to guide physicians in the management of patients, particularly those having sustained a traumatic brain injury. Researchers in ...
Mondal Tapas K - - 2013
Abstract We report a case of a fetus with hypoplastic left heart syndrome in addition to an anomalous vessel extending from the descending thoracic aorta to the basal segments of the lower left lung without sequestration. The concurrence of these two congenital abnormalities is extremely rare and unreported in the ...
Ni Haifang - - 2013
This work introduces a facile strategy for the synthesis of carbon-coated LiFePO(4)-porous carbon (C-LiFePO(4)-PC) composites as a cathode material for lithium ion batteries. The LiFePO(4) particles obtained are about 200 nm in size and homogeneously dispersed in porous carbon matrix. These particles are further coated with the carbon layers pyrolyzed ...
Armstrong L E - - 2013
BACKGROUND/OBJECTIVES:This investigation evaluated 12 hydration biomarkers, to determine which represent 24-h whole-body water balance (that is, measured as water retention or clearance (WR-C) by the kidneys).SUBJECTS/METHODS:Healthy males (n=59; body mass, 75.1±7.9 kg; height, 178±6 cm; age, 22±3 years; body mass index, 23.9±2.4 kg/m(2)) met with a registered dietitian each morning (days 1-11) to ...
Shahim Pashtun - - 2013
Tangier disease (TD) is a rare genetic disorder caused by mutations in the ATP-binding cassette transporter A1 (ABCA1) gene, which results in impaired cellular cholesterol efflux and high-density lipoprotein cholesterol deficiency. Animal and in vitro studies indicate that ABCA1 is involved in the production of amyloid-β (Aβ), a pivotal protein ...
Rathbun S - - 2013
Objective: This report summarizes the findings of the consensus panel based on the results of the comprehensive questionnaire of US American College of Phlebology annual congress attendees and results of the systematic meta-analysis of the literature and provides quality improvement guidelines for the use of endovenous foam sclerotherapy (EFS) for ...
Shen Minghui - - 2013
The complete mitochondrial genome (mitogenome) sequence of squaretail coralgrouper Plectropomus areolatus was determined with long PCR approach. The genome was 16,770 bp in length and contained 13 protein-coding genes, 22 transfer RNAs (tRNAs), 2 ribosomal RNAs (rRNAs), and 2 non-coding regions, with the gene content and order being similar to most ...
Svenningsson Anders - - 2013
A 32-year-old woman presented with multiple sclerosis (MS) in 2001, displaying typical MS features on MRI and in the CSF. The patient's clinical condition was relatively stable without major exacerbations on interferon beta-1a but MRI investigation in September 2007 noted a significant progression in lesions (figure, A) but without contrast ...
Walker Mary P - - 2013
Purpose: Difficult impression removal has been linked to high rigidity and hardness of elastomeric impression materials. In response to this concern, manufacturers have reformulated their materials to reduce rigidity and hardness to decrease removal difficulty; however, the relationship between impression removal and rigidity or hardness has not been evaluated. The ...
Moreau François - - 2013
BACKGROUND AND PURPOSE: The use of magnetic resonance imaging (MRI) after transient ischemic attack (TIA) or minor stroke may be affected by the relative timing of imaging. We measured the impact of scanning an individual patient late versus early after TIA and minor stroke. METHODS: Two hundred sixty-three TIA or ...
Zhang Min - - 2013
A molecular beacon (MB)-like DNA hairpin biosensor based on the reversible directing fluorescence of Hoechst dyes was developed for fluorescent detection of Hg(2+) and biothiols and furthermore for logic operation.
Beeman Scott C - - 2013
PURPOSE: The goal of this work was to detect disease-related microstructural changes to the liver using magnetic resonance imaging. Chronic liver disease can cause microstructural changes in the liver that reduce plasma access to the perisinusoidal space-the site of exchange between the blood plasma and the hepatic parenchyma. The reduced ...
Markoff Lewis - - 2013
On November 16, 2012, the Weekly Epidemiological Record of the World Health Organization (WHO) reported that an outbreak of yellow fever was under way in Sudan. By the end of November, the disease had been detected in 26 localities in Sudan's Darfur region, with 459 suspected cases and 116 related ...
Abuabara Allan - - 2013
Root canal perforation and root resorption are challenging clinical conditions to correctly diagnose and treat, especially when they occur in anterior teeth. This clinical report describes the computed tomography findings, endodontic treatment, prosthetic rehabilitation, and clinical outcome of an iatrogenic root perforation and internal resorption in a maxillary central incisor. ...
Leonhardt Ralf M - - 2013
PMEL (also called Pmel17 or gp100) is a melanocyte/melanoma-specific glycoprotein that plays a critical role in melanosome development by forming a fibrillar amyloid matrix in the organelle for melanin deposition. Although ultimately not a component of mature fibrils, the PMEL N-terminal region (NTR) is essential for their formation. By mutational ...
Wever Kimberley E - - 2013
BackgroundRenal ischaemia-reperfusion injury (IRI) is a common clinical problem associated with significant mortality and morbidity. One strategy to reduce this damage is remote ischaemic preconditioning (RIPC), in which brief ischaemia of a limb protects the kidney against a prolonged ischaemic insult. The mechanism of renal RIPC has not yet been ...
Li Qian - - 2013
Human bocavirus (HBoV), closely related to canine minute virus (MVC) and bovine parvovirus (BPV), is a new member of the Bocavirus genus within the Parvoviridae family. The non-structural protein NP1 of HBoV is a nuclear localized protein and plays important role in DNA replication as well as in the evasion ...
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