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Codling Dale John - - 2013
Nuclear magnetic resonance diffusion studies can be used to identify different compounds in a mixture. However, since the diffusion coefficient is primarily dependent on the effective hydrodynamic radius, it is particularly difficult to resolve compounds with similar size and structure, such as isomers, on the basis of diffusion. Differential solution ...
Holland D J - - 2013
PURPOSE: Functional MRI (fMRI) techniques that can provide excellent blood oxygen level dependent contrast, rapid whole brain imaging, and minimal spatial distortion are in demand. This study explored whether fMRI sensitivity can be improved through the use of compressed sensing (CS) reconstruction of variable density spiral fMRI. METHODS: Three different ...
Yin Xinyou X Centre for Crop Systems Analysis, Department of Plant Sciences, Wageningen University, PO Box 430, 6700 AK Wageningen, The Netherlands. - - 2013
Process-based ecophysiological crop models are pivotal in assessing responses of crop productivity and designing strategies of adaptation to climate change. Most existing crop models generally over-estimate the effect of elevated atmospheric [CO2], despite decades of experimental research on crop growth response to [CO2]. A review of the literature indicates that ...
Pasquale Frank L - - 2013
Polymer films have been formed by electron-induced cross-linking of condensed ortho-carborane and benzene (B(10)C(2)H(X):BNZ) or pyridine (B(10)C(2)H(X):py) at 110 K, followed by warming up to room temperature. High resolution core-level photoemission and molecular orbital calculations demonstrate that the reaction of the icosahedra with the aromatic group is site-specific: bonding occurs between ...
Turner Damian L - - 2013
In healthy individuals, influenza virus (IAV) infection generally remains localized to the epithelial cells of the respiratory tract. Previously, IAV-specific effector CD8 T cells found systemically during the course of IAV infection were thought to have been primed in lung-draining lymph nodes with subsequent migration to other tissues. However, little ...
Zheng Zhen - - 2013
Spindle positioning is believed to be governed by the interaction between astral microtubules and the cell cortex, and involve cortically anchored motor protein dynein. How dynein is recruited to and regulated at the cell cortex to generate forces on astral microtubules is not clear. Here, we show that LGN, a ...
Lu Y H YH Key Laboratory of Public Health Safety of Ministry of Education - Department of Epidemiology, Fudan University School of Public Health, Shanghai, - - 2013
We studied seasonal patterns of swine hepatitis E virus (HEV) infection in China. From 2008 to 2011, 4200 swine bile specimens were collected for the detection of HEV RNA. A total of 92/2400 (3·83%) specimens in eastern China and 47/1800 (2·61%) specimens in southwestern China were positive for HEV. Seasonal ...
Mahlik S - - 2013
Photoluminescence spectra and luminescence kinetics of pure CaMoO(4) and CaMoO(4) doped with Ln(3+) (Ln = Pr or Tb) are presented. The spectra were obtained at high hydrostatic pressure up to 240 kbar applied in a diamond anvil cell. At ambient pressure undoped and doped samples exhibit a broad band emission extending between 380 ...
Oh Hwamee - - 2013
Both cognitive aging and β-amyloid (Aβ) deposition, a pathological hallmark of Alzheimer's disease, are associated with structural and cognitive changes in cognitively normal older people. To examine independent effects of age and Aβ deposition on cognition and brain structure in aging, 83 cognitively normal older adults underwent structural magnetic resonance ...
Cristofaro Rebecca G Riera Di - - 2013
Purpose: The aim of this study was to establish the wear and cutting efficiency of tungsten carbide burs from different manufacturers by performing cutting tests with machinable glass ceramic. Materials and Methods: Cutting tests were performed with 70 tungsten carbide burs from seven manufacturers: (A) Coltene/Whaledent, (B) CEI, (C) Meisinger, ...
Zhang Shuai - - 2013
Uncontrolled misfolding of proteins leading to the formation of amyloid deposits is associated with more than 40 types of diseases, such as neurodegenerative diseases and type-2 diabetes. These irreversible amyloid fibrils typically assemble in distinct stages. Transitions among the various intermediate stages are the subject of many studies but are ...
Hulten Kristina G - - 2013
Among 594 Streptococcus pneumoniae serotype 19A invasive pneumococcal disease (IPD) isolates collected from 1993 to 2011, we identified 85 sequence types by multilocus sequence typing. CC320 was associated with multidrug resistance and reduced susceptibility to penicillin and ceftriaxone and still predominated among declining serotype 19A IPD isolates following PCV13 introduction.
Zhou Huaiyang - - 2013
The global ridge system is dominated by oceanic rises reflecting large variations in axial depth associated with mantle hotspots. The little-studied Marion Rise is as large as the Icelandic Rise, considering both length and depth, but has an axial rift (rather than a high) nearly its entire length. Uniquely along ...
Mendez-Gallardo Valerie - - 2013
Early locomotion in the neonatal rat previously has been reported 3 days after birth during exposure to an odor of biological relevance (nest material). The current study explores if other ecologically relevant stimuli-amniotic fluid (AF) and milk-could evoke a similar locomotor response in the newborn rat and whether the endogenous ...
Shambat Gary - - 2013
Single-cell interrogation at the nanoscale can take on many forms-namely, pillars(1), tubes(2-5), and wires(6-8) as probes for gentle insertion into a cell's interior, allowing for studies on single-cell cargo delivery(4), electrochemistry(3) or electrophysiology(1), and optical signaling(9-10). However, optical probes such as nanowires(9) or tapered fibers(10) are passive in nature and ...
Veillette Annabelle - - 2013
The occurrence of apoptosis and cell survival in the receptive uterus is intimately involved in the embryo implantation process in order to facilitate embryo attachment to the maternal endometrium. The initial stimulus leading to successful implantation might be triggered by the conceptus itself. By the end of rat embryo implantation, ...
Chandarana Hersh - - 2013
PURPOSE: To assess dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) tracer pharmacokinetic parameters obtained with Generalized Kinetic Model (GKM) and extended Shutter Speed Model (SSM2) in renal tumors stratified by histologic subtypes. MATERIALS AND METHODS: In all, 24 patients with renal tumors were imaged at 1.5 T utilizing DCE-MRI with ...
Vogt Ferdinand F Department of Cardiac Surgery, Klinikum Nürnberg, Nuremberg, Germany. - - 2013
Aortic homografts are an alternative to mechanical or biological valve prostheses. Homografts are generally not transplanted ABO-compatible while this policy is still under debate. The purpose of this study was to investigate whether ABO compatibility impacts on long-term outcomes or not. Between 1992 and 2009, 363 adult patients with a ...
Ong Mei-Sing - - 2013
ABSTRACT: BACKGROUND: Ineffective communication of infection control requirements during transitions of care is a potential cause of non-compliance with infection control precautions by healthcare personnel. In this study, interventions to enhance communication during inpatient transfers between wards and radiology were implemented, in the attempt to improve adherence to precautions during ...
Vos Miriam B - - 2013
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in adults and children. A number of genetic and environmental factors are known to predispose individualsto NAFLD. Certain dietary sugars, particularly fructose, are suspected to contribute to the development of NAFLD and its progression. The increasing quantity of ...
Casasnovas Rodrigo - - 2013
This study reports the carbon acidities of Cα and C4' atoms in the Schiff bases of pyridoxal-5'-phosphate (PLP) and pyridoxamine-5'-phosphate (PMP) complexed with several biologically available metal ions (Mg2+, Ni2+, Zn2+, Cu2+, Al3+ and Fe3+). Density Functional Theory calculations were carried out to determine the free energies of proton exchange ...
Yoo Roh-Eul - - 2013
PURPOSE: To evaluate the usefulness of pseudo-continuous arterial spin labeling (pCASL) imaging in differentiating high-grade gliomas from lymphomas and in noninvasively predicting genetic biomarkers in high-grade gliomas. MATERIALS AND METHODS: Twelve glioblastoma multiforme (GBM), 3 anaplastic astrocytoma (AA), 5 recurred GBM, and 9 lymphoma patients underwent conventional MR and pCASL ...
Paßvogel Lars - - 2013
The nuclear egress complex (NEC) is required for efficient translocation of newly synthesized herpesvirus nucleocapsids from the nucleus to the cytosol. It consists of the type II membrane protein pUL34 which interacts with pUL31 at the inner nuclear membrane (INM). To map regions within pUL34 required for nuclear membrane targeting ...
Perkins Lynda E LE School of Biological Sciences, The University of Queensland, Brisbane, Queensland 4072, Australia. - - 2013
Plants are sessile, so have evolved sensitive ways to detect attacking herbivores and sophisticated strategies to effectively defend themselves. Insect herbivory induces synthesis of the phytohormone jasmonic acid which activates downstream metabolic pathways for various chemical defences such as toxins and digestion inhibitors. Insects are also sophisticated animals, and many ...
Ni Haifang - - 2013
This work introduces a facile strategy for the synthesis of carbon-coated LiFePO(4)-porous carbon (C-LiFePO(4)-PC) composites as a cathode material for lithium ion batteries. The LiFePO(4) particles obtained are about 200 nm in size and homogeneously dispersed in porous carbon matrix. These particles are further coated with the carbon layers pyrolyzed ...
Ford Kevin J KJ Department of Molecular and Cellular Biology, University of California, Berkeley, CA, - - 2013
Slow afterhyperpolarizations (sAHPs) play an important role in establishing the firing pattern of neurons that in turn influence network activity. sAHPs are mediated by calcium-activated potassium channels. However, the molecular identity of these channels and the mechanism linking calcium entry to their activation are still unknown. Here we present several ...
Armstrong L E - - 2013
BACKGROUND/OBJECTIVES:This investigation evaluated 12 hydration biomarkers, to determine which represent 24-h whole-body water balance (that is, measured as water retention or clearance (WR-C) by the kidneys).SUBJECTS/METHODS:Healthy males (n=59; body mass, 75.1±7.9 kg; height, 178±6 cm; age, 22±3 years; body mass index, 23.9±2.4 kg/m(2)) met with a registered dietitian each morning (days 1-11) to ...
Shahim Pashtun - - 2013
Tangier disease (TD) is a rare genetic disorder caused by mutations in the ATP-binding cassette transporter A1 (ABCA1) gene, which results in impaired cellular cholesterol efflux and high-density lipoprotein cholesterol deficiency. Animal and in vitro studies indicate that ABCA1 is involved in the production of amyloid-β (Aβ), a pivotal protein ...
Rathbun S - - 2013
Objective: This report summarizes the findings of the consensus panel based on the results of the comprehensive questionnaire of US American College of Phlebology annual congress attendees and results of the systematic meta-analysis of the literature and provides quality improvement guidelines for the use of endovenous foam sclerotherapy (EFS) for ...
Okamoto Keiji - - 2013
Mammalian telomeres repress DNA-damage activation at natural chromosome ends by recruiting specific inhibitors of the DNA-damage machinery that form a protective complex termed shelterin. Within this complex, TRF2 (also known as TERF2) has a crucial role in end protection through the suppression of ATM activation and the formation of end-to-end ...
Burns Michael B MB Biochemistry, Molecular Biology and Biophysics Department, University of Minnesota, Minneapolis, Minnesota 55455, - - 2013
Several mutations are required for cancer development, and genome sequencing has revealed that many cancers, including breast cancer, have somatic mutation spectra dominated by C-to-T transitions. Most of these mutations occur at hydrolytically disfavoured non-methylated cytosines throughout the genome, and are sometimes clustered. Here we show that the DNA cytosine ...
Shen Minghui - - 2013
The complete mitochondrial genome (mitogenome) sequence of squaretail coralgrouper Plectropomus areolatus was determined with long PCR approach. The genome was 16,770 bp in length and contained 13 protein-coding genes, 22 transfer RNAs (tRNAs), 2 ribosomal RNAs (rRNAs), and 2 non-coding regions, with the gene content and order being similar to most ...
Gallo Valentina V Department of Epidemiology and Biostatistics, School of Public Health, Imperial College, London, UK. - - 2013
The aim of this study was to investigate for the first time the association between body fat and risk of amyotrophic lateral sclerosis (ALS) with an appropriate prospective study design. The EPIC (European Prospective Investigation into Cancer and Nutrition) study included 518,108 individuals recruited from the general population across 10 ...
Svenningsson Anders - - 2013
A 32-year-old woman presented with multiple sclerosis (MS) in 2001, displaying typical MS features on MRI and in the CSF. The patient's clinical condition was relatively stable without major exacerbations on interferon beta-1a but MRI investigation in September 2007 noted a significant progression in lesions (figure, A) but without contrast ...
Walker Mary P - - 2013
Purpose: Difficult impression removal has been linked to high rigidity and hardness of elastomeric impression materials. In response to this concern, manufacturers have reformulated their materials to reduce rigidity and hardness to decrease removal difficulty; however, the relationship between impression removal and rigidity or hardness has not been evaluated. The ...
Moreau François - - 2013
BACKGROUND AND PURPOSE: The use of magnetic resonance imaging (MRI) after transient ischemic attack (TIA) or minor stroke may be affected by the relative timing of imaging. We measured the impact of scanning an individual patient late versus early after TIA and minor stroke. METHODS: Two hundred sixty-three TIA or ...
Zhang Min - - 2013
A molecular beacon (MB)-like DNA hairpin biosensor based on the reversible directing fluorescence of Hoechst dyes was developed for fluorescent detection of Hg(2+) and biothiols and furthermore for logic operation.
Beeman Scott C - - 2013
PURPOSE: The goal of this work was to detect disease-related microstructural changes to the liver using magnetic resonance imaging. Chronic liver disease can cause microstructural changes in the liver that reduce plasma access to the perisinusoidal space-the site of exchange between the blood plasma and the hepatic parenchyma. The reduced ...
Markoff Lewis - - 2013
On November 16, 2012, the Weekly Epidemiological Record of the World Health Organization (WHO) reported that an outbreak of yellow fever was under way in Sudan. By the end of November, the disease had been detected in 26 localities in Sudan's Darfur region, with 459 suspected cases and 116 related ...
Abuabara Allan - - 2013
Root canal perforation and root resorption are challenging clinical conditions to correctly diagnose and treat, especially when they occur in anterior teeth. This clinical report describes the computed tomography findings, endodontic treatment, prosthetic rehabilitation, and clinical outcome of an iatrogenic root perforation and internal resorption in a maxillary central incisor. ...
Giphart J Erik - - 2013
Understanding glenohumeral motion in normal and pathologic states requires the precise measurement of shoulder kinematics. The effect of the plane of arm elevation on glenohumeral translations and rotations remains largely unknown. The purpose of this study was to measure the three-dimensional glenohumeral translations and rotations during arm elevation in healthy ...
Harden Lois M - - 2013
ABSTRACT: BACKGROUND: Whereas the role played by interleukin (IL)-10 in modulating fever and sickness behavior has been linked to it targeting the production of pro-inflammatory cytokines in the circulation, liver and spleen, it is not known whether it could directly target the local production of pro-inflammatory cytokines within the sensory ...
Kurtzer Isaac I Dept. of Biomedical Sciences, New York Institute of Technology College of Osteopathic Medicine, Old Westbury, NY 11568, USA. - - 2013
Damage to the cerebellum can cause significant problems in the coordination of voluntary arm movements. One prominent idea is that incoordination stems from an inability to predictively account for the complex mechanical interactions between the arm's several joints. Motivated by growing evidence that corrective feedback control shares important capabilities and ...
Brembeck Petra - - 2013
Low maternal vitamin D status during pregnancy may have negative consequences for both mother and child. There are few studies of vitamin D status and its determinants in pregnant women living at northern latitudes. Thus, the present study investigates vitamin D status and its determinants during the third trimester of ...
Fahrmayr C - - 2013
BACKGROUND AND PURPOSE: Hepatic uptake (e.g. by OATP1B1), phase I and II metabolism (e.g. by CYP3A4, UGT1A1) and subsequent biliary excretion (e.g. by MRP2) are key determinants for the pharmacokinetics of numerous drugs. However, stably transfected cell models for the simultaneous investigation of transport and phase I and II metabolism ...
El-Achkar Tarek M TM Division of Nephrology, Indiana University and Roudebush Indianapolis Veterans Affairs Medical Center, Indianapolis, IN 46202, USA. - - 2013
Tamm-Horsfall protein (THP) is a glycoprotein normally targeted to the apical membrane domain of the kidney's thick ascending limbs (TAL). We previously showed that THP of TAL confers protection to proximal tubules against acute kidney injury (AKI) via a possible cross talk between the two functionally distinct tubular segments. However, ...
Barnucz Eniko - - 2013
Storage protocols of vascular grafts need further improvement against ischemia/reperfusion (IR)-injury. Hypoxia elicits a variety of complex cellular responses by altering the activity of many signalling pathways, such as the oxygen-dependent prolyl-hyroxylase-domain containing enzyme (PHD). Reduction of PHD-activity during hypoxia leads to stabilisation and accumulation of hypoxia inducible factor (HIF) ...
Gupta R R Department of Otolaryngology and Head and Neck Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, - - 2013
Frontal sinus involvement in aspergillosis associated with the nose and paranasal sinuses is a common occurrence, but the incidence of primary frontal sinus aspergillosis is rare, and there are few reports in the English literature. This study aimed to evaluate the role of the endonasal endoscopic surgical approach for isolated ...
Moodley Thunicia - - 2013
Post-hoc analysis of two phase III clinical studies found that the phosphodiesterase 4 (PDE4) inhibitor, roflumilast, reduced exacerbation frequency in patients with severe chronic obstructive pulmonary disease (COPD) who were taking inhaled corticosteroids (ICS) concomitantly, whereas patients not taking ICS derived no such benefit. In contrast, in two different trials ...
Huq S - - 2013
This article evaluates the outcome of 42 consecutive zone 1 flexor tendon injuries treated by using micro bone anchors during the period 2003-2008. Patients were rehabilitated using the modified Belfast Regime. The range of motion at the distal interphalangeal joint was assessed using Moiemen's classification. A total of 56% of ...
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