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Jelic Vesna - - 2013
Previous findings demonstrated an altered pattern of amyloid-β protein precursor (AβPP) expression in platelets of Alzheimer's disease (AD) patients compared with either healthy control subjects or patients with non-Alzheimer-type dementia. In an attempt to explore the diagnostic potential of platelet AβPP metabolism, we have generated monoclonal antibodies directed to the ...
Sadowsky Steven J - - 2013
Evidence-based criteria for differential implant planning for the partially edentulous patient have been lacking despite the exponential use of implant reconstructions. Anecdotal reports are often the basis for training of dental students and the continuing education of dentists and specialists. Decision-making metrics for optimal dental treatment are best predicated on ...
Bazzicalupi Carla - - 2013
The second-generation poly(ethylene imine) dendrimer (L), based on ammonia as the initiating core molecule, forms stable metal complexes in aqueous solution. Speciation of the complex species formed and determination of the relevant stability constants were performed by means of potentiometric titration in 0.10 M NMe(4)Cl solution at 298.1 K. The ...
Tashiro Sanki - - 2013
Facultative heterochromatin is reversibly established and disrupted during differentiation, but its regulation remains mechanistically unclear. Here, we show that two meiotic gene loci in fission yeast, mei4 and ssm4, comprise facultative heterochromatin that is regulated in a developmental stage-dependent manner. This heterochromatin coordinates expression levels by associating with a chromodomain ...
Sheng Liming - - 2013
Previous studies found that the ABO blood type alters the individual susceptibility of some malignancies. However, whether such an association exists between ABO blood type and nasopharyngeal carcinoma (NPC) remains unknown. A case-control study was conducted, with 1538 patients who had NPC and 1260 cancer-free controls. The association between ABO ...
Chan Tak Kwong - - 2013
Adults without the capacity to make their own medical decisions have their rights protected under the Mental Capacity Act (2005) in the UK. The underlying principle of the court's decisions is the best interests test, and the evaluation of best interests is a welfare appraisal. Although the House of Lords ...
Moreira Nuno Canto - - 2013
Objective :  To evaluate the ability of brain-targeted magnetic resonance imaging (MRI) to assess the anatomy of the fetal upper lip and palate. Design :  Two independent readers made a blind retrospective review of 60 brain-targeted MRIs of fetuses from 20 to 38 gestational weeks (GW). Fifty-five MRIs were normal ...
Hood R Lyle - - 2013
BACKGROUND AND OBJECTIVES: The fiberoptic microneedle device (FMD) seeks to leverage advantages of both laser-induced thermal therapy (LITT) and convection-enhanced delivery (CED) to increase volumetric dispersal of locally infused chemotherapeutics through sub-lethal photothermal heat generation. This study focused on determination of photothermal damage thresholds with 1,064 nm light delivered through the ...
Demir Mehmet - - 2013
Non-dipper hypertension is associated with increased cardiovascular morbidity and mortality. Neutrophil/lymphocyte ratio (NLR) has been associated with poor outcomes in patients with cardiovascular diseases. However, little is known about the role of NLR in patients with non-dipper hypertension. In this study, NLR between dipper and non-dipper hypertensive patients was compared.This ...
- - 2013
The Underside of the Silver Tsunami - Older Adults and Mental Health Care Perspective, N Engl J Med 2013;368:493-496. In the penultimate paragraph (page 496), the first sentence should have read, "We believe that steps should be taken to mandate the inclusion of older adults in federally funded research unless ...
Della Marca Giacomo - - 2013
OBJECTIVE: To measure the presence of the alpha-sleep anomaly in facioscapulohumeral muscular dystrophy (FSHD) and to evaluate the association between the sleep electroencephalogram (EEG) pattern and the presence of musculoskeletal pain. DESIGN: Cross-sectional study. SETTING: Sleep laboratory. SUBJECTS: Fifty-five consecutive adult FSHD patients, 26 women and 29 men, age 49.6 ± 15.1 ...
Sahoo Prativa - - 2013
PURPOSE: To modify the generalized tracer kinetic model (GTKM) by introducing an additional tissue uptake leakage compartment in extracellular extravascular space (LTKM). In addition, an implicit determination of voxel-wise local arterial input function (AIF) C(p) (t) was performed to see whether these changes help in better discrimination between low- and ...
Jereb Marjan - - 2013
Iodine was demonstrated to be an efficient catalyst for disproportionation of aryl-substituted ethers under solvent-free reaction conditions. Variously substituted 1,1,1',1'-tetraaryldimethyl ethers were transformed into the corresponding diarylketone and diarylmethane derivatives. I(2)-catalyzed transformation of 4-methoxyphenyl substituted ethers yielded mono- and dialkylated Friedel-Crafts products as well. Treatment of trityl alkyl and trityl ...
King Albert W - - 2013
The complex [Ru(bpy)(2)(bpSO)](PF(6))(2), where bpy is 2,2'-bipydine and bpSO is 1,2-bis(phenylsulfinyl)ethane, exhibits three distinct isomers which are accessible upon metal-to-ligand charge-transfer (MLCT) irradiation. This complex and its parent, [Ru(bpy)(2)(bpte)](PF(6))(2), where bpte is 1,2-bis(phenylthio)ethane, have been synthesized and characterized by UV-visible spectroscopy, NMR, X-ray crystallography, and femtosecond transient absorption spectroscopy. A ...
Polychronakis Nick - - 2013
Purpose: This survey was conducted to study the prevalence of partial edentulism, the type of removable partial denture (RPD) support, the type of major connectors, and the frequency of their use in relation to the partial edentulism classes encountered, concerning patients in Athens, Greece. Materials and Methods: The material comprised ...
Cui B - - 2013
We demonstrate that the uniaxial magnetic anisotropy (UMA) of amorphous CoFeB films can be tuned by crystallinity and orbital moment ratio, combining the results of magnetization reversal and ferromagnetic resonance with high-resolution transmission electron microscopy, x-ray-absorption near-edge structure and x-ray magnetic circular dichroism. Isotropic polycrystalline buffers of tungsten (W), tantalum ...
Zaidel Jacob - - 2013
Known analytical solutions of groundwater flow equations are routinely used for verification of computer codes. However, these analytical solutions (e.g., the Dupuit solution for the steady-state unconfined unidirectional flow in a uniform aquifer with a flat bottom) represent smooth and continuous water table configurations, simulating which does not pose any ...
Waterman Amy D - - 2013
BACKGROUND: Although U.S. transplantation programs must submit living-donor follow-up data through 2 years after donation, the submissions have high rates of incomplete or missing data. It is important to understand barriers programs face in collecting follow-up information. METHODS: Two hundred thirty-one programs performing living kidney donor (LKD) and/or living liver ...
Fu Dechen - - 2013
How Fanconi anemia (FA) protein D2 (FANCD2) performs DNA damage repair remains largely elusive. We report here that translesion synthesis DNA polymerase (pol) eta is a novel mediator of FANCD2 function. We found that wild type (wt) FANCD2, not K561R (mt) FANCD2, can interact with pol eta. Upon DNA damage, ...
Auchincloss Amy H - - 2013
OBJECTIVE: Numerous localities have mandated that chain restaurants post nutrition information at the point of purchase. However, some studies suggest that consumers are not highly responsive to menu labelling. The present qualitative study explored influences on full-service restaurant customers' noticing and using menu labelling. DESIGN: Five focus groups were conducted ...
Russell Ailsa J - - 2013
BACKGROUND: High rates of anxiety disorders, particularly obsessive compulsive disorder (OCD) are reported in people with Autism spectrum disorders (ASD). Group cognitive behavioral treatment (CBT) has been found effective for anxiety in young people with ASD but not been OCD specific. One uncontrolled pilot study of individual CBT for OCD ...
Kubicki Rouven - - 2013
OBJECTIVES: As an inflammatory reaction after cardiac surgery involving cardiopulmonary bypass (CPB), capillary leak syndrome (CLS) is associated with increased morbidity, especially in newborns and infants. We investigated whether different cytokines measured via microdialysis can monitor local inflammation in adipose tissue subcutaneously and predict the development of CLS early, before ...
Dos Santos Rodrigo Pires - - 2013
We developed an antimicrobial stewardship programme, based on telemedicine, for a remote community hospital in southern Brazil. Expertise in infectious diseases was provided from a 250-bed tertiary hospital for cardiology patients located 575 km away. At the community hospital, antimicrobial prescriptions were completed via a secure web site. A written ...
Jack Darby - - 2013
OBJECTIVE: Recommendations for fruit and vegetable consumption are largely unmet. Lower socio-economic status (SES), neighbourhood poverty and poor access to retail outlets selling healthy foods are thought to predict lower consumption. The objective of the present study was to assess the interrelationships between these risk factors as predictors of fruit ...
Greci Laura S - - 2013
Introduction During a pandemic influenza, emergency departments will be overwhelmed with a large influx of patients seeking care. Although all hospitals should have a written plan for dealing with this surge of health care utilization, most hospitals struggle with ways to educate the staff and practice for potentially catastrophic events. ...
Hwang Dae-Sik - - 2013
The complete mitochondrial genome was sequenced from the river lamprey, Lampetra japonica. The genome sequence was 16,267 bp in size, and the gene order and contents were identical with the genera Lampetra reissneri. However, L. japonica has two control regions with different mitochondrial genomic organization compared to other previously reported fish ...
Olsen Oystein Erlend - - 2013
Magnetic resonance imaging (MRI) is rich in diagnostic information but requires optimization for use in children. The main problems are motion artifacts and poor signal-to-noise ratio (SNR). SNR is proportional to voxel volume, which must therefore not be too small, however, usually needs to be reduced compared to adult imaging ...
Evered Andrew - - 2013
BACKGROUND: Acquisition of visual interpretation skills in cytopathology may involve 2 strategies. Analytic strategies require trainees to base their interpretive decisions on carefully considered and often exhaustive cytomorphologic feature lists, a process that can be time-consuming and inefficient. In contrast, nonanalytic pattern recognition strategies are rarely encouraged during training, even ...
Regina Vasconcelos Ligia - - 2013
Purpose: The purpose of this study was to evaluate the effect of simulated disinfections (2% glutaraldehyde, 1% sodium hypochlorite, and microwave energy) on the surface hardness of Trilux, Biocler, Biotone, New Ace, and Magister commercial artificial teeth. Materials and Methods: Specimens (n = 10) were made with the teeth included ...
Yeung Pollen K F - - 2013
OBJECTIVE: The mechanisms of exercise-induced health benefits are complex and not fully understood. This study investigated the effects of exercise and hypertension on cardiovascular hemodynamic responses and red blood cell (RBC) concentrations of purine nucleotides using normotensive and hypertensive rat models in vivo. METHODS: Sprague Dawley rats (SDRs) and spontaneously ...
Matafome P - - 2013
The relation between cancer and metabolic disorders was proposed several decades ago but the complete puzzle of the mechanisms involved in cancer development and progression remain obscure. In the last years many groups have been studying systemic adipose markers in cancer patients. However, few consistent results were obtained. On the ...
Powell Idona - - 2013
AIM: To report a study that explored the experiences of night-shift nurses, focusing on employee interrelationships and work satisfaction. BACKGROUND: Night-shift nurses are a critical component in hospital care making it essential to understand the experiences that give meaning to their work and understand how these nurses and the organization ...
Wang Kun - - 2013
A new assay of micellar electrokinetic capillary chromatography with sweeping was developed to determine azoxystrobin, kresoxim-methyl and pyraclostrobin in fruits and vegetables. The key factors affecting resolution and peak height were studied and the optimum conditions were obtained for separation and enrichment. The running buffer consisted of 40 mM borate, ...
Martin James N JN - - 2013
OBJECTIVE: We explored the prevalence of Composite Major Maternal Morbidity (CMMM) for patients with severe preeclampsia (SPRE) and each class or category of HELLP syndrome. METHODS: In a retrospective cohort study from 2000-2010, we reviewed maternal charts of patients categorized with complete or partial HELLP syndrome. From 2005-2007 the maternal ...
Higashi Takahiro - - 2013
Ensuring the quality of care is a major objective of cancer control policy. The Cancer Control Act 2006 placed responsibility on the Japanese government to maintain the quality of cancer care nationwide. To function as centers providing high-quality care, designated cancer care hospitals (397 hospitals as of April 2012) were ...
Cardoso A S - - 2013
A survey of intestinal parasites in dogs was carried out in a rural region around Cantanhede, in northern Portugal, where 301 dog faecal samples were collected from small-ruminant farms. Saturated salt flotation and formol-ether sedimentation techniques were used. An enquiry was conducted in 234 farms and a risk factor evaluation ...
Kelly P C - - 2013
The objective of this study was to validate four key farmer performance indicators (KFPI), identified in a previous study, as indicators of on-farm cattle welfare incidents in Ireland, through comparison of the distribution of these KPFIs in the national herd (n=109,925) and in case herds (n=18), where welfare incidents were ...
Shanmugam Nesan - - 2013
AIMS: Following CRT, atrioventricular (AV) optimization is not routinely practised. To evaluate its clinical utility, we examined the effect of AV delay optimization on the prognostic biomarker NT-proBNP. METHODS AND RESULTS: We prospectively studied 72 patients (mean age 73 ± 12.5 years, 70.8% male, 55.6% ischaemic) undergoing iterative AV optimization. ...
Tasca G - - 2013
Defects in the posttranslational modification of α-dystroglycan (α-DG) have been implicated in clinically distinct dystroglycanopathies that present as congenital muscular dystrophies with multisystem involvement, limb-girdle muscular dystrophies (LGMDs), or a spectrum of intermediate phenotypes.(1,2) Recently, mutations in ISPD, encoding the isoprenoid synthase domain containing protein, have been described in Walker-Warburg ...
Nonaka Yasuhiro - - 2013
Galectin-9 is a lectin, which has various biological functions such as T cell differentiation and apoptosis. Multivalency of carbohydrate binding is required for galectin-9 to function. While galectin-1 (a proto-type galectin) forms an oligomer to obtain its multivalency, galectin-9 (a tandem-repeat-type one) has two carbohydrate recognition domains (CRD) in one ...
Grønlund Mette - - 2013
Arbuscular mycorrhizal fungi (AMF) have a key role in plant phosphate (Pi) uptake by their efficient capture of soil phosphorus (P) that is transferred to the plant via Pi transporters in the root cortical cells. The activity of this mycorrhizal Pi uptake pathway is often associated with down-regulation of Pi ...
Liu Zhiqiang - - 2013
Nanocrystalline BaFCl:Sm3+, as prepared by co-precipitation from aqueous solutions, is an efficient photoluminescent X-ray storage phosphor. In the present study, we report effects on its photoluminescence properties resulting from post-annealing treatment in air in the temperature range between 100 to 900 ºC. Interestingly, upon annealing at temperatures from 200 to ...
Akc─▒lar Raziye - - 2013
Apelin, a novel multifunctional peptide implicated in the regulation of the cardiovascular system, including blood pressure and cardiac function control, has been postulated to be involved in the pathophysiology of hypertension and hypertensive heart disease. The aim of this study was to investigate, for the first time, whether the effects ...
Young Stephen G - - 2013
A clinical trial of a protein farnesyltransferase inhibitor (lonafarnib) for the treatment of Hutchinson-Gilford progeria syndrome (HGPS) was recently completed. Here, we discuss the mutation that causes HGPS, the rationale for inhibiting protein farnesyltransferase, the potential limitations of this therapeutic approach, and new potential strategies for treating the disease.
Sharma Amy M - - 2013
Nevirapine (NVP) treatment is associated with serious skin rashes that appear to be immune-mediated. We previously developed a rat model of this skin rash that is immune-mediated and very similar to the rash in humans. Treatment of rats with the major NVP metabolite, 12-OH-NVP, also caused the rash. Most idiosyncratic ...
Murata Mitsutaka - - 2013
In this study, we investigated the feasibility of a system based on liposomal surface modification with a novel mucoadhesive polymer-lectin conjugate for the pulmonary delivery of therapeutic peptides and proteins. We covalently attached wheat germ agglutinin (WGA), a ligand that specifically interacts with alveolar epithelial cells, to carbopol (CP), a ...
Marrie Ruth Ann - - 2013
ABSTRACT: BACKGROUND: While mental comorbidity is considered common in multiple sclerosis (MS), its impact is poorly defined; methods are needed to support studies of mental comorbidity. We validated and applied administrative case definitions for any mental comorbidities in MS. METHODS: Using administrative health data we identified persons with MS and ...
Qiao Huiying - - 2013
In this paper, we determined complete mitochondrial DNA sequence of Schizopygopsis younghusbandi. The mitogenome is 16,674 bp in length, which includes 22 tRNA genes, 2 rRNA genes, 13 protein-coding genes, and 2 non-coding regions: control region (D-loop) and origin of light-strand replication (O(L)). The complete mitogenome sequence of S. younghusbandi is ...
Ko Jeong Min - - 2013
Background: Bronchiectasis in tuberculosis (TB) is usually considered chronic traction bronchiectasis associated with healed scars. However, bronchiectasis can occasionally be seen in active TB.Purpose: To evaluate prevalence, appearance, and changes of bronchiectasis associated with active TB on computed tomography (CT).Material and Methods: A total of 391 patients with active TB ...
Yang Wei - - 2013
Metabonomics is an important platform for investigating the metabolites of integrated living systems and their dynamic responses to changes caused by both endogenous and exogenous factors. A metabonomics strategy based on LC-MS/MS in both positive and negative ion modes was applied to investigate the short-term and long-term stability of metabolites ...
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