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Zaidel Jacob - - 2013
Known analytical solutions of groundwater flow equations are routinely used for verification of computer codes. However, these analytical solutions (e.g., the Dupuit solution for the steady-state unconfined unidirectional flow in a uniform aquifer with a flat bottom) represent smooth and continuous water table configurations, simulating which does not pose any ...
Waterman Amy D - - 2013
BACKGROUND: Although U.S. transplantation programs must submit living-donor follow-up data through 2 years after donation, the submissions have high rates of incomplete or missing data. It is important to understand barriers programs face in collecting follow-up information. METHODS: Two hundred thirty-one programs performing living kidney donor (LKD) and/or living liver ...
Fu Dechen - - 2013
How Fanconi anemia (FA) protein D2 (FANCD2) performs DNA damage repair remains largely elusive. We report here that translesion synthesis DNA polymerase (pol) eta is a novel mediator of FANCD2 function. We found that wild type (wt) FANCD2, not K561R (mt) FANCD2, can interact with pol eta. Upon DNA damage, ...
Auchincloss Amy H - - 2013
OBJECTIVE: Numerous localities have mandated that chain restaurants post nutrition information at the point of purchase. However, some studies suggest that consumers are not highly responsive to menu labelling. The present qualitative study explored influences on full-service restaurant customers' noticing and using menu labelling. DESIGN: Five focus groups were conducted ...
Russell Ailsa J - - 2013
BACKGROUND: High rates of anxiety disorders, particularly obsessive compulsive disorder (OCD) are reported in people with Autism spectrum disorders (ASD). Group cognitive behavioral treatment (CBT) has been found effective for anxiety in young people with ASD but not been OCD specific. One uncontrolled pilot study of individual CBT for OCD ...
Kubicki Rouven - - 2013
OBJECTIVES: As an inflammatory reaction after cardiac surgery involving cardiopulmonary bypass (CPB), capillary leak syndrome (CLS) is associated with increased morbidity, especially in newborns and infants. We investigated whether different cytokines measured via microdialysis can monitor local inflammation in adipose tissue subcutaneously and predict the development of CLS early, before ...
Dos Santos Rodrigo Pires - - 2013
We developed an antimicrobial stewardship programme, based on telemedicine, for a remote community hospital in southern Brazil. Expertise in infectious diseases was provided from a 250-bed tertiary hospital for cardiology patients located 575 km away. At the community hospital, antimicrobial prescriptions were completed via a secure web site. A written ...
Jack Darby - - 2013
OBJECTIVE: Recommendations for fruit and vegetable consumption are largely unmet. Lower socio-economic status (SES), neighbourhood poverty and poor access to retail outlets selling healthy foods are thought to predict lower consumption. The objective of the present study was to assess the interrelationships between these risk factors as predictors of fruit ...
Greci Laura S - - 2013
Introduction During a pandemic influenza, emergency departments will be overwhelmed with a large influx of patients seeking care. Although all hospitals should have a written plan for dealing with this surge of health care utilization, most hospitals struggle with ways to educate the staff and practice for potentially catastrophic events. ...
Hwang Dae-Sik - - 2013
The complete mitochondrial genome was sequenced from the river lamprey, Lampetra japonica. The genome sequence was 16,267 bp in size, and the gene order and contents were identical with the genera Lampetra reissneri. However, L. japonica has two control regions with different mitochondrial genomic organization compared to other previously reported fish ...
Olsen Oystein Erlend - - 2013
Magnetic resonance imaging (MRI) is rich in diagnostic information but requires optimization for use in children. The main problems are motion artifacts and poor signal-to-noise ratio (SNR). SNR is proportional to voxel volume, which must therefore not be too small, however, usually needs to be reduced compared to adult imaging ...
Evered Andrew - - 2013
BACKGROUND: Acquisition of visual interpretation skills in cytopathology may involve 2 strategies. Analytic strategies require trainees to base their interpretive decisions on carefully considered and often exhaustive cytomorphologic feature lists, a process that can be time-consuming and inefficient. In contrast, nonanalytic pattern recognition strategies are rarely encouraged during training, even ...
Regina Vasconcelos Ligia - - 2013
Purpose: The purpose of this study was to evaluate the effect of simulated disinfections (2% glutaraldehyde, 1% sodium hypochlorite, and microwave energy) on the surface hardness of Trilux, Biocler, Biotone, New Ace, and Magister commercial artificial teeth. Materials and Methods: Specimens (n = 10) were made with the teeth included ...
Yeung Pollen K F - - 2013
OBJECTIVE: The mechanisms of exercise-induced health benefits are complex and not fully understood. This study investigated the effects of exercise and hypertension on cardiovascular hemodynamic responses and red blood cell (RBC) concentrations of purine nucleotides using normotensive and hypertensive rat models in vivo. METHODS: Sprague Dawley rats (SDRs) and spontaneously ...
Matafome P - - 2013
The relation between cancer and metabolic disorders was proposed several decades ago but the complete puzzle of the mechanisms involved in cancer development and progression remain obscure. In the last years many groups have been studying systemic adipose markers in cancer patients. However, few consistent results were obtained. On the ...
Powell Idona - - 2013
AIM: To report a study that explored the experiences of night-shift nurses, focusing on employee interrelationships and work satisfaction. BACKGROUND: Night-shift nurses are a critical component in hospital care making it essential to understand the experiences that give meaning to their work and understand how these nurses and the organization ...
Wang Kun - - 2013
A new assay of micellar electrokinetic capillary chromatography with sweeping was developed to determine azoxystrobin, kresoxim-methyl and pyraclostrobin in fruits and vegetables. The key factors affecting resolution and peak height were studied and the optimum conditions were obtained for separation and enrichment. The running buffer consisted of 40 mM borate, ...
Martin James N JN - - 2013
OBJECTIVE: We explored the prevalence of Composite Major Maternal Morbidity (CMMM) for patients with severe preeclampsia (SPRE) and each class or category of HELLP syndrome. METHODS: In a retrospective cohort study from 2000-2010, we reviewed maternal charts of patients categorized with complete or partial HELLP syndrome. From 2005-2007 the maternal ...
Bliss Katherine T - - 2013
Focal adhesions are intricate protein complexes that facilitate cell attachment, migration and cellular communication. Lasp-2 (LIM-nebulette), a member of the nebulin family of actin-binding proteins, is a newly identified component of these complexes. To gain further insights into the functional role of lasp-2, we identified two additional binding partners of ...
Lustig Brian R - - 2013
In rats, navigating through an environment requires continuous information about objects near the head. Sensory information such as object location and surface texture are encoded by spike firing patterns of single neurons within rat barrel cortex. Although there are many studies using single unit electrophysiology, much less is known regarding ...
Higashi Takahiro - - 2013
Ensuring the quality of care is a major objective of cancer control policy. The Cancer Control Act 2006 placed responsibility on the Japanese government to maintain the quality of cancer care nationwide. To function as centers providing high-quality care, designated cancer care hospitals (397 hospitals as of April 2012) were ...
Cardoso A S - - 2013
A survey of intestinal parasites in dogs was carried out in a rural region around Cantanhede, in northern Portugal, where 301 dog faecal samples were collected from small-ruminant farms. Saturated salt flotation and formol-ether sedimentation techniques were used. An enquiry was conducted in 234 farms and a risk factor evaluation ...
Kelly P C - - 2013
The objective of this study was to validate four key farmer performance indicators (KFPI), identified in a previous study, as indicators of on-farm cattle welfare incidents in Ireland, through comparison of the distribution of these KPFIs in the national herd (n=109,925) and in case herds (n=18), where welfare incidents were ...
Shanmugam Nesan - - 2013
AIMS: Following CRT, atrioventricular (AV) optimization is not routinely practised. To evaluate its clinical utility, we examined the effect of AV delay optimization on the prognostic biomarker NT-proBNP. METHODS AND RESULTS: We prospectively studied 72 patients (mean age 73 ± 12.5 years, 70.8% male, 55.6% ischaemic) undergoing iterative AV optimization. ...
Tasca G - - 2013
Defects in the posttranslational modification of α-dystroglycan (α-DG) have been implicated in clinically distinct dystroglycanopathies that present as congenital muscular dystrophies with multisystem involvement, limb-girdle muscular dystrophies (LGMDs), or a spectrum of intermediate phenotypes.(1,2) Recently, mutations in ISPD, encoding the isoprenoid synthase domain containing protein, have been described in Walker-Warburg ...
Nonaka Yasuhiro - - 2013
Galectin-9 is a lectin, which has various biological functions such as T cell differentiation and apoptosis. Multivalency of carbohydrate binding is required for galectin-9 to function. While galectin-1 (a proto-type galectin) forms an oligomer to obtain its multivalency, galectin-9 (a tandem-repeat-type one) has two carbohydrate recognition domains (CRD) in one ...
Kecskemeti Steve - - 2013
PURPOSE: To develop and validate a novel free-breathing 3D radial late gadolinium-enhanced magnetic resonance imaging technique (3D LGE-MRI) with isotropic resolution and retrospective inversion time (TI) selection for myocardial viability imaging. MATERIALS AND METHODS: The 3D radial LGE-MRI method featuring an interleaved and bit-reversed radial k-space trajectory was evaluated in ...
Grønlund Mette - - 2013
Arbuscular mycorrhizal fungi (AMF) have a key role in plant phosphate (Pi) uptake by their efficient capture of soil phosphorus (P) that is transferred to the plant via Pi transporters in the root cortical cells. The activity of this mycorrhizal Pi uptake pathway is often associated with down-regulation of Pi ...
Liu Zhiqiang - - 2013
Nanocrystalline BaFCl:Sm3+, as prepared by co-precipitation from aqueous solutions, is an efficient photoluminescent X-ray storage phosphor. In the present study, we report effects on its photoluminescence properties resulting from post-annealing treatment in air in the temperature range between 100 to 900 ºC. Interestingly, upon annealing at temperatures from 200 to ...
Akc─▒lar Raziye - - 2013
Apelin, a novel multifunctional peptide implicated in the regulation of the cardiovascular system, including blood pressure and cardiac function control, has been postulated to be involved in the pathophysiology of hypertension and hypertensive heart disease. The aim of this study was to investigate, for the first time, whether the effects ...
Young Stephen G - - 2013
A clinical trial of a protein farnesyltransferase inhibitor (lonafarnib) for the treatment of Hutchinson-Gilford progeria syndrome (HGPS) was recently completed. Here, we discuss the mutation that causes HGPS, the rationale for inhibiting protein farnesyltransferase, the potential limitations of this therapeutic approach, and new potential strategies for treating the disease.
Sharma Amy M - - 2013
Nevirapine (NVP) treatment is associated with serious skin rashes that appear to be immune-mediated. We previously developed a rat model of this skin rash that is immune-mediated and very similar to the rash in humans. Treatment of rats with the major NVP metabolite, 12-OH-NVP, also caused the rash. Most idiosyncratic ...
Murata Mitsutaka - - 2013
In this study, we investigated the feasibility of a system based on liposomal surface modification with a novel mucoadhesive polymer-lectin conjugate for the pulmonary delivery of therapeutic peptides and proteins. We covalently attached wheat germ agglutinin (WGA), a ligand that specifically interacts with alveolar epithelial cells, to carbopol (CP), a ...
Marrie Ruth Ann - - 2013
ABSTRACT: BACKGROUND: While mental comorbidity is considered common in multiple sclerosis (MS), its impact is poorly defined; methods are needed to support studies of mental comorbidity. We validated and applied administrative case definitions for any mental comorbidities in MS. METHODS: Using administrative health data we identified persons with MS and ...
Qiao Huiying - - 2013
In this paper, we determined complete mitochondrial DNA sequence of Schizopygopsis younghusbandi. The mitogenome is 16,674 bp in length, which includes 22 tRNA genes, 2 rRNA genes, 13 protein-coding genes, and 2 non-coding regions: control region (D-loop) and origin of light-strand replication (O(L)). The complete mitogenome sequence of S. younghusbandi is ...
Ko Jeong Min - - 2013
Background: Bronchiectasis in tuberculosis (TB) is usually considered chronic traction bronchiectasis associated with healed scars. However, bronchiectasis can occasionally be seen in active TB.Purpose: To evaluate prevalence, appearance, and changes of bronchiectasis associated with active TB on computed tomography (CT).Material and Methods: A total of 391 patients with active TB ...
Wong Grace Lai-Hung - - 2013
Entecavir is a potent antiviral agent with high genetic barrier to resistance, hence is currently recommended as first-line antiviral therapy for chronic hepatitis B (CHB). The aim of this study was to investigate the efficacy of entecavir on clinical outcomes and deaths. It was a retrospective-prospective cohort study based on ...
Yang Wei - - 2013
Metabonomics is an important platform for investigating the metabolites of integrated living systems and their dynamic responses to changes caused by both endogenous and exogenous factors. A metabonomics strategy based on LC-MS/MS in both positive and negative ion modes was applied to investigate the short-term and long-term stability of metabolites ...
Patrick Jaminet - - 2013
BACKGROUND: Less is known about the role of Netrin-1 in the peripheral nervous system. In this study, we evaluated the role of Netrin-1 using the mouse median nerve model for assessment of peripheral nerve regeneration. METHODS: Using real-time PCR and Western Blot analysis, we examined expression changes of Netrin-1 mRNA ...
Breljak Davorka - - 2013
In the mouse kidney, organic anion transporter 3 (mOat3, Slc22a8) was previously localized to the basolateral membrane (BLM) of proximal tubule (PT), thick ascending limb of Henle, macula densa, distal tubule, and cortical collecting duct. However, the specificity of anti-Oat3 antibodies (Oat3-Ab) used in these studies was not properly verified. ...
Okumura Ken-Ichi - - 2013
Lateral root (LR) formation in vascular plants is regulated by auxin. The mechanisms of LR formation are not fully understood. Here, we have identified a novel recessive mutation in Arabidopsis thaliana, named fewer roots (fwr), that drastically reduces the number of LRs. Expression analyses of DR5::GUS, an auxin response reporter, ...
Bezard Erwan - - 2013
The serotonin (5-hydroxytryptamine [5HT]) system has recently emerged as an important player in the appearance of l-3,4-dihydroxyphenylalanine (levodopa [l-dopa])-induced dyskinesia in animal models of Parkinson's disease. In fact, dopamine released as a false transmitter from serotonin neurons appears to contribute to the pulsatile stimulation of dopamine receptors, leading to the ...
Ahern Fiona - - 2013
BACKGROUND: Adverse drug reactions (ADR) cause considerable morbidity and mortality. METHODS: This 4-week study was undertaken in Cork University Hospital, Ireland, for all admissions from the emergency department (ED). A panel independently reviewed patients with suspected ADRs. Causality assessment was performed using the Naranjo ADR probability scale and the Hallas ...
de Oliveira Paulo R N - - 2013
The cytotoxic activity of crude extracts and their fractions from leaves and roots of G. pohliana was assessed against nine human cancer cell lines: melanoma (UACC-62), breast (MCF-7), breast expressing the multidrug resistance phenotype (NCI-ADR), lung (NCI-460), prostate (PCO-3), kidney (786-0), ovarian (OVCAR), colon (HT-29) and leukaemia (K-562). The hexane ...
Chu Fong Lam - - 2013
To facilitate the detection of acrylamide or styrene adduct of amino acids by mass spectrometry based techniques, phenylalanine was used as a representative amino acid and pyrolysis was employed in conjunction with isotope labeling technique as a micro-scale sample preparation tool to generate the reaction products. The residues remaining after ...
Kalayciyan Raffi - - 2013
PURPOSE: To develop a sodium-MRI ((23) Na-MRI) method for bilateral renal sodium concentration (RSC) measurements in rat kidneys at 9.4 Tesla (T). MATERIALS AND METHODS: To simultaneously achieve high B(1) -field homogeneity and high receive sensitivity a dual resonator system composed of a double-tuned linearly polarized (1) H/(23) Na volume ...
Shin Jaemin - - 2013
PURPOSE: To develop an improved and generalized technique for correcting T1-related signal fluctuations (T1 effect) in cardiac-gated functional magnetie resonance imaging (fMRI) data with flip angle estimation. THEORY AND METHODS: Spatial maps of flip angle and T1 are jointly estimated from cardiac-gated time series using a Kalman filter. These maps ...
Courivaud Cécile - - 2013
BACKGROUND: Fractalkine (CX3CL1) and its receptor (CX3CR1) are involved in antitumor immunity. Two common single nucleotide polymorphisms of the CX3CR1 gene, V249I and T280M, have been associated with reduced fractalkine signaling characterized by decreased adhesive function, signaling, and chemotaxis of leukocytes. We hypothesized that a renal transplant recipient (RTR) carrying ...
Fabricant Peter D - - 2013
Subtle variations in acetabular morphology have been implicated in several pathologic hip conditions. Although it is understood that the acetabulum forms at the junction of the ilium, ischium, and pubis at the triradiate cartilage, the ossification and development pattern of the posterior wall of the acetabulum is unknown. Standard radiographs ...
Wachira Benjamin W - - 2013
Kenya's major incidents profile is dominated by droughts, floods, fires, terrorism, poisoning, collapsed buildings, accidents in the transport sector and disease/epidemics. With no integrated emergency services and a lack of resources, many incidents in Kenya escalate to such an extent that they become major incidents. Lack of specific training of ...
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