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McLoone J K - - 2013
BACKGROUND: Providing ongoing clinical care that adequately addresses patients' medical, psychosocial and information needs is challenging, particularly for patient groups at increased risk of developing life-threatening disease such as malignant melanoma. This study examined a model of clinical care developed by the High Risk Clinic (HRC) of the Sydney Melanoma ...
Pacini Simone - - 2013
Mesechymal Stromal Cells (MSCs) are a heterogeneous cell population capable of differentiating towards several cell lines in vitro and, possibly, in vivo. Within cultured MSCs we identified and purified a precursor cell population (Mesodermal Progenitor Cells, MPCs) retaining robust proliferation potential and ability to differentiate into endothelial or mesenchymal cells. ...
Zhang Xinke - - 2013
Ag@zinc-tetraphenylporphyrin (Ag@ZnTPP) core-shell nanostructures have been fabricated by in situ chemical deposition. Unusual thickness-dependent fluorescence allowed their colour to be tuned from blue to red by simply increasing the shell thickness from ∼2 nm to ∼9 nm. The competition between metal enhancement and the self-absorption effect of ZnTPP has been ...
Xu Guobin - - 2013
Here we present the novel functionalization of detonation nanodiamond (dND) with amino-phenyl boronic acid (APBA) assisted by poly-l-lysine (PL) and PEG-diglycolic acid (PEG) (dND-p-APBA). With the assistance of biocompatible poly-l-lysine and PEG, dND-p-APBA particles show good dispersibility in aqueous solution and plentiful boronic acid functional groups on the surface, which ...
Leinonen Tuomas - - 2013
Comparative studies of the divergence of quantitative traits and neutral molecular markers, known as Q(ST)-F(ST) comparisons, provide a means for researchers to distinguish between natural selection and genetic drift as causes of population differentiation in complex polygenic traits. The use of Q(ST)-F(ST) comparisons has increased rapidly in the last few ...
Jakubowski Henry V - - 2013
To help faculty prepare and revise courses in all the disciplines represented in the MCAT(2015) , the American Association of Medical Colleges, through its MedEdPORTAL's iCollaborative, has established the Pre-health Collection, a repository of reviewed web resources that are openly and freely available to faculty, and indirectly through them to ...
Xue Pengchong - - 2013
Being different from common sensing molecules existing as monomer in solution, the gelators as sensing molecules self-assembled together in gels. Therefore, the interaction strength between gelators is believed as an important factor for gels to recognize selectively anions. In this paper, we choose two gelators, presenting similar binding sites for ...
Wasay Mohammad - - 2013
Neurology is one of the most underrecognized and underappreciated specialties in Pakistan.(1) The beginnings of clinical and academic neurology in Pakistan can be traced to the 1960s when 3 neurology departments were established in 2 major cities of Pakistan: 2 in Karachi and 1 in Lahore.(2,3) One of the 2 ...
Passos Marco A - - 2013
ABSTRACT: BACKGROUND: Although banana (Musa sp.) is an important edible crop, contributing towards poverty alleviation and food security, limited transcriptome datasets are available for use in accelerated molecular-based breeding in this genus. 454 GS-FLX Titanium technology was employed to determine the sequence of gene transcripts in genotypes of Musa acuminata ...
Sørensen M K MK Department of Anaesthesia, Centre of Head and Orthopaedics, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark. - - 2013
Tracheal intubation may cause vocal fold damage. The trial was designed to assess laryngeal morbidity comparing the Endoflex(®) tube with a conventional endotracheal tube with stylet. We hypothesised that laryngeal morbidity within the first 24 h after extubation would be lower with the Endoflex tube than with the conventional endotracheal ...
Filippone Edward J - - 2013
Idiopathic membranous nephropathy (iMN) is a single-organ autoimmune disease characterized by subepithelial deposition of immune complexes containing IgG4 resulting in proteinuria, nephrotic syndrome, and, in some, end-stage renal disease. The pathogenesis involves a chronic IgG4 response against specific podocyte antigens which have now been at least partially defined in the ...
Thielbeer Frank - - 2013
Abstract Nano materials are commonly functionalized to boost their physicochemical properties. However, there is little known about the impact of these modifications on cellular systems. Herein, we synthesized 8 types of polymeric nanoparticles bearing different functional groups, and investigated their effects on interactions with cellular membranes. As models for particle- ...
Straumann A - - 2013
BACKGROUND: Eosinophilic esophagitis (EoE) is a chronic, Th2-type inflammatory disease. Chemoattractant receptor-homologous molecule on Th2 cells (CRTH2) is a prostaglandin D(2) (PGD(2) ) receptor, expressed by Th2 cells and other inflammatory cells, including eosinophils and basophils, that mediates chemotaxis and activation. OC000459 is a selective CRTH2 antagonist and would be ...
Inadera Hidekuni H Department of Public Health, Faculty of Medicine, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan. - - 2013
Obesity is a leading risk factor for impaired glucose tolerance and type 2 diabetes (T2D). Although the cause of the obesity epidemic is multi-factorial and not entirely clear, the recent acceleration in incidence is too rapid to be accounted for only by genetics, the wide availability of calorie-rich foods, and ...
Richter Wito W Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San Francisco, San Francisco, California 94143, - - 2013
It is generally assumed that antagonists of Gs-coupled receptors do not activate cAMP signalling, because they do not stimulate cAMP production via Gs-protein/adenylyl cyclase activation. Here, we report a new signalling pathway whereby antagonists of β1-adrenergic receptors (β1ARs) increase cAMP levels locally without stimulating cAMP production directly. Binding of antagonists ...
Suezawa Takanori T Department of Cardiovascular Surgery, Kagawa Prefectural Central Hospital, 5-4-16 Ban-cho, Takamatsu, Kagawa 760-8557, Japan. - - 2013
It has not been established whether off-pump coronary artery bypass grafting (OPCABG) is less invasive than conventional CABG. In our experience, OPCABG has several advantages such as shorter operative duration, decreased requirement of blood transfusion and myocardial protection compared with conventional CABG. However, frequency of postoperative paroxysmal atrial fibrillation (PAF) ...
Kim Oh Cheol - - 2013
The thermotolerant methylotrophic yeast Hansenula polymorpha is able to grow at elevated temperature up to 48 °C as one of a few yeast strains which are naturally capable of alcoholic fermentation of xylose, a pentose sugar abundant in lignocellulosic biomass. However, the current level of ethanol production from xylose by H. ...
Chapalain Annelise - - 2013
The Burkholderia cepacia complex (Bcc) comprises strains with a virulence potential toward immunocompromised patients as well as plant growth-promoting rhizobacteria (PGPR). Owing to the link between quorum sensing (QS) and virulence, most studies among Bcc species have been directed toward QS of pathogenic bacteria. We have investigated the QS of ...
Tsukushi Satoshi - - 2013
BACKGROUND: Whether to preserve or sacrifice critical structures (bone, major vessels and major nerves) adjacent to soft tissue sarcomas is still controversial. Referring to characteristic imaging and intraoperative findings, we perform planned preservation surgery for these critical structures. The aim of this study was to investigate the clinical outcome of ...
Altemani Albina - - 2013
AIMS: Signet-ring cell (SRC) change has not been reported in adenoid cystic carcinoma (ACC). The aim of this study was to describe the clinicopathological and immunohistochemical findings in four cases of ACC with SRCs (ACC-SRC), in which the relative proportion of the SRC component ranged from 25% to 50%. METHODS ...
Federici Anita - - 2013
OBJECTIVE: This study presents case-series data on a novel outpatient program that blends dialectical behavior therapy (DBT) with standard eating disorder (ED) interventions (i.e., food exposure, weight monitoring, cognitive modification, ED psychoeducation) for patients with complex and multidiagnostic ED presentations. METHOD: Quantitative and qualitative data was collected on a sample ...
Boosani Chandra S CS Creighton University School of Medicine, Department of Biomedical Sciences, Omaha, NE 68178, - - 2013
PTEN (phosphatase and tensin homolog deleted on chromosome 10) plays a pivotal role in controlling intracellular signaling for cell survival and proliferation by inhibiting the PI3K/Akt pathway, and its dysfunction is associated with several neoplastic diseases. PTEN is frequently found mutated in many pathological conditions highlighting its importance in normal ...
Ahn Hyo-Jin - - 2013
Dual-scale diamond-shaped gold nanostructures (d-DGNs) with larger scale diamond-shaped gold nanoposts (DGNs) coupled to smaller scale gold nanoparticles have been fabricated via interference lithography as a highly reliable and efficient substrate for surface enhanced Raman scattering (SERS). The inter- and intra-particle plasmonic fields of d-DGNs are varied by changing the ...
Sheth C H - - 2013
BACKGROUND: Patients undergoing radiotherapy or chemoradiotherapy treatment for head and neck cancer have an increased risk of malnutrition, and may require enteral feeding via nasogastric or gastrostomy tube. The aim of this audit was to examine current enteral feeding practice, mortality, morbidity and 6-month outcome data of head and neck ...
Roeker L E - - 2013
The purpose of this study was to determine if there is an increased risk of acute leukemia and myelodysplastic syndromes (MDS) in persons with monoclonal gammopathy of undetermined significance (MGUS). We utilized a large population-based cohort of individuals systematically screened for the presence or absence of MGUS. MGUS status was ...
Batuk Maria - - 2013
The nuclear and magnetic structure of a novel oxychloride Pb(4)BiFe(4)O(11)Cl has been studied over the temperature range 1.5-700 K using a combination of transmission electron microscopy and synchrotron and neutron powder diffraction [space group P4/mbm, a = 5.5311(1) Å, c = 19.586(1) Å, T = 300 K]. Pb(4)BiFe(4)O(11)Cl is built ...
Reese Aspen T - - 2013
Pika species generally fall into two ecotypes, meadow-dwelling (burrowing) or talus-dwelling, a classification that distinguishes a suite of different ecological, behavioral, and life history traits. Despite these differences, little morphological variation has previously been documented to distinguish among ecotypes. The aim of this study was to test whether postcranial features ...
Moore R R Department of Infectious Diseases, Mater Misericordiae University Hospital, Dublin, - - 2013
Klebsiella pneumoniae has emerged as a predominant cause of community-acquired mono-microbial pyogenic liver abscess. This was first described in Taiwan and has been widely reported in Asia. This infectious entity has been described in Europe, with single case reports predominating. We present three cases in one year from our institution ...
Vester Boler Brittany M - - 2013
This study sought to determine fermentation potential of human milk oligosaccharides by mixed cultures of fecal microbiota from breast-fed (BF; n=4) and formula-fed (FF; n=4) infants. Infant fecal inocula were incubated with galactooligosaccharide (GOS), gum arabic (GA), HP inulin (HP), 2'-fucosyllactose (2'FL), 6'-sialyllactose (6'SL), and lacto-N-neotetraose (LNnt). GOS, 2'FL, and ...
Ceylan-Isik Asli F AF Center for Cardiovascular Research and Alternative Medicine, University of Wyoming College of Health Sciences, Laramie, WY 82071, - - 2013
Cardiac aging is manifested as cardiac remodeling and contractile dysfunction although precise mechanisms remain elusive. This study was designed to examine the role of endothelin-1 (ET-1) in aging-associated myocardial morphological and contractile defects. Echocardiographic and cardiomyocyte contractile properties were evaluated in young (5-6 months) and old (26-28 months) C57BL/6 wild-type and cardiomyocyte-specific ...
Sobhanardakani S - - 2013
In this study, the removal of Cr(III) and Cu(II) from contaminated wastewaters by rice husk, as an organic solid waste, was investigated. Experiments were performed to investigate the influence of wastewater initial concentration, pH of solution, and contact time on the efficiency of Cr(III) and Cu(II) removal. The results indicated ...
Roth Timothy C TC - - 2013
Enhancements to memory are associated with enhanced neural structures that support those capabilities. A great deal of work has examined this relationship in the context of natural variation in spatial memory capability and hippocampal structure (hereafter Hp). Most studies have focused on volumetric and neuron measures, but have seldom examined ...
Esfahani Shadi Abdar - - 2013
The Weigert-Meyer rule predicts the draining pattern of duplex ureters in bipolar renal duplications. This paper introduces two cases of nonpolar renal duplication. A 3-month-old and a 15-year-old female with history of urinary tract infection were evaluated with intravenous pyelograms (IVP) and eleven different parameters were analyzed. The infant's IVP ...
Pokladnikova Jitka - - 2013
Objective. The aim of the study was to investigate the effectiveness and feasibility of conducting a complementary 8-week comprehensive lifestyle modification program (CLMP) compared to standard care in patients with bronchial asthma over a 6-month period. Methods. This was a randomized controlled pilot trial with two groups: intervention (N = 15) group ...
Labib Mahmoud - - 2013
A novel attempt was made to develop a disposable multifunctional sensor for analysis of vaccinia virus (VACV), a promising oncolytic agent that can replicate in and kill tumor cells. Briefly, we developed aptamers specific to VACV that were negatively selected against human serum as well as human and mouse blood ...
Hamamé Carlos M - - 2013
The visual word form area in the ventral occipitotemporal cortex develops with acquisition of reading skills. It is debated whether this region is specialized for reading(1) or is rather a general-purpose area associating visual form (words, objects) with meaning. An outline of this debate can be found in appendix e-1 ...
Galindo José - - 2013
ABSTRACT: Pancreatic cancer remains as one of the most aggressive human neoplasms, with overall poor survival rates. Radical surgery of the primary lesion is the best option for treatment. Borderline resectable pancreatic tumors (BRPT), defined as partial involvement of peripancreatic vasculature, may benefit from neoadjuvant therapy. We report on the ...
Zheng Dianyuan - - 2013
Oxytetracycline (OTC), a broad-spectrum antibiotic, has been extensively used as a food additive for livestock. Its extensive use has greatly increased the risk of chronic drug abuse and has also increased the risk of the resulting diseases. Therefore, in light of this emerging situation, the detection of OTC in both ...
Alghamdi Mohammed M Division of Cardiology, Department of Pediatrics, British Columbia Children's Hospital, The University of British Columbia, Vancouver, BC, - - 2013
Chronic kidney disease (CKD) is known to cause increased arterial stiffness, which is an important independent risk factor for adverse cardiovascular events. The purpose of this study was to assess the vascular properties of the aorta (AO) in a group of children with CKD using a noninvasive echocardiography (echo)-Doppler method. ...
Kade I J - - 2013
Redox imbalances and altered signaling processes in the brain are characteristic features of diabetic complications. Hence, the present study therefore sought to evaluate the effect of gallic acid (GA) on disturbed redox systems and activity of neurotransmission signaling dependent enzymes such as sodium pump, purinergic enzymes and acetylcholinesterase in diabetic ...
Spevak Lyudmila L Hospital for Special Surgery, 535 E. 70th Street, New York, NY 10021, - - 2013
Acid phosphate substitution into mineralized tissues is an important determinant of their mechanical properties and their response to treatment. This study identifies and validates Fourier transform infrared spectroscopic imaging (FTIRI) spectral parameters that provide information on the acid phosphate (HPO4) substitution into hydroxyapatite in developing mineralized tissues. Curve fitting and ...
Okuyama Yusuke - - 2013
BACKGROUND: To investigate the associations between serum concentrations of carotenoids and the presence of colorectal polyps and cancers in Japanese using a cross-sectional study. METHODS: 893 subjects who underwent colorectal endoscopy between 2001 and 2002 provided serum samples and information on lifestyle factors. Serum concentrations of six carotenoids were compared ...
Kim Shin-Hyun - - 2013
Polymersomes, vesicles composed of bilayer membranes of amphiphilic block-copolymers, are promising delivery vehicles for long-term storage and controlled release of bioactives; enhanced stability of the membrane makes polymersomes potentially useful in a wide range of biological delivery applications by comparison with liposomes. However, unilamellar structure is intrinsically fragile when subjected ...
Svetel Marina V - - 2013
Brain-derived neurotrophic factor (BDNF) modulates neuroplasticity. A functional polymorphism [Val66Met (G196A)] in BDNF has been reported to modify cortical plasticity in humans. Physiologic investigations have revealed that dystonia might be a consequence of the pathologic plasticity of the sensorimotor cortex. We aimed to investigate the role of the Val66Met polymorphism ...
Kuhan G - - 2013
PURPOSE: To carry out a systematic review of randomized trials comparing surgery vs. endovascular therapy for occluded fistulas and grafts. METHODS: All randomized trials which compared surgery and endovascular therapy for occluded fistulas and grafts were retrieved from 1990 onwards. The following search terms were used: "haemodialysis," "thrombosis," "arteriovenous fistula," ...
Qu Xinhua - - 2013
High bone mineral density (BMD) has been associated with increased breast cancer in prospective studies of postmenopausal women, but the real relationship is still controversial. Therefore, we undertook a meta-analysis to evaluate the association between BMD and the risk of breast cancer in postmenopausal women. We performed systematic searches on ...
Nicdao Ethel G - - 2013
This study investigates the prevalence and predictors of using complementary and alternative medicine (CAM) among middle-aged and older patients prior to cardiac surgery. Additionally, it addresses the correlates of using 10 commonly used CAM therapies. The influence of religion on itemized CAM usage is also explored. Comprehensive data were collected ...
Bosy-Westphal A A Institute of Human Nutrition and Food Science, Christian-Albrechts University, Kiel, - - 2013
Although weight cycling is frequent in obese patients, the adverse consequences on body composition and an increased propensity to weight gain remain controversial. We investigated the effect of intentional weight loss and spontaneous regain on fat distribution, the composition of lean mass and resting energy expenditure (REE). Weight regainers (≥ ...
Mori Kohji - - 2013
Genetic analysis revealed the hexanucleotide repeat expansion GGGGCC within the regulatory region of the gene C9orf72 as the most common cause of familial amyotrophic lateral sclerosis and the second most common cause of frontotemporal lobar degeneration. Since repeat expansions might cause RNA toxicity via sequestration of RNA-binding proteins, we searched ...
Bakkali M - - 2013
DNA acquisition promotes the spread of resistance to antibiotics and virulence among bacteria. It is also linked to several natural phenomena including recombination, genome dynamics, adaptation and speciation. Horizontal DNA transfer between bacteria occurs via conjugation, transduction or competence for natural transformation by DNA uptake. Among these, competence is the ...
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