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Sobotka Roman - - 2013
Chlorophyll (Chl) is an essential component of the photosynthetic apparatus. Embedded into Chl-binding proteins, Chl molecules play a central role in light harvesting and charge separation within the photosystems. It is critical for the photosynthetic cell to not only ensure the synthesis of a sufficient amount of new Chl-binding proteins ...
Hu Fangyun - - 2013
Nanoscaled two-dimensional (2D) chiral architectures are increasingly receiving scientific interest because of their potential applications in many domains. In this paper, we present a new method for constructing 2D chiral architectures on surface. Based on in situ Schiff-base reaction of achiral dialdehyde with two kinds of achiral amines at the ...
Spaulding Tammie J - - 2013
The receptive vocabulary performance of pre-school children with specific language impairment (SLI) and typically-developing (TD) controls was compared on the Peabody Picture Vocabulary Test third and fourth edition (PPVT-III and PPVT-IV) to determine consistency in performance and the effect of test revision on identification of impairment. Participants included 40 pre-school ...
Runciman Phyllis - - 2013
Aim This article presents an interpretation of health promotion within the work of a district nurse (DN). BACKGROUND: Literature supports the centrality of health promotion within nursing. It also presents debate about its meaning and suggests uncertainties for educators and practitioners about its relationship to nursing care. Two studies in ...
Barberá Rafael - - 2013
BACKGROUND: Frey's syndrome (FS), facial depression, and noticeable scar may have an impact on patient's quality of life after a parotidectomy. The superficial musculoaponeurotic system (SMAS) flap has been used to ameliorate those effects. METHODS: Forty-seven consecutive parotidectomies were analyzed; SMAS flap was performed in 26 of them. We investigated ...
Aho Kevin A - - 2013
This paper integrates personal narratives with the methods of phenomenology in order to draw some general conclusions about 'what it means' and 'what it feels like' to be depressed. The analysis has three parts. First, it explores the ways in which depression disrupts everyday experiences of spatial orientation and motility. ...
Agache Ioana O - - 2013
ABSTRACT: Hypersensitivity pneumonitis (HP) is an interstitial lung disease due to a combined type III and IV reaction with a granulomatous inflammation, caused by cytotoxic delayed hypersensitivity lymphocytes, in a Th1/Th17 milieu, chaperoned by a deficient suppressor function of T regulatory cells. Skewing toward a Th2 phenotype is reported for ...
Valentino L A - - 2013
In haemophilia patients with well-established high-titer inhibitors, even seemingly minor acute bleeding episodes or surgical procedures may become refractory to treatment and transform into limb- or life-threatening situations. In the absence of evidence-based treatment guidelines, this article presents 10 cases of difficult to control acute and surgical bleeding and offers ...
Herculano L S - - 2013
Eosin Y is known to be a powerful probe of biological molecules and an efficient photosensitizing agent for the production of singlet molecular oxygen. Under continuous laser excitation, degradation through photobleaching is observed in aqueous solutions of eosin Y; this process is driven by the production of singlet oxygen. Optical ...
Hruskova Z - - 2013
Objectives: Alveolar haemorrhage (AH) is a major cause of early death in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). There is a paucity of information regarding the outcomes of AAV patients presenting with severe AH. Method: A retrospective cohort study. Patients with severe AH were identified from a case review of ...
Fernandes Geórgea Hermogenes - - 2013
Necrotizing autoimmune myopathy (NAM) is a severe adverse effect of statins. We report a 66-year-old Caucasian female who had progressive proximal muscle weakness after treatment with statins. Results of a muscle biopsy showed necrotizing myopathy with minimal inflammatory cell infiltrate and increased major histocompatibility class I antigen expression in muscle ...
Kutushov M - - 2013
Rhodamine-6G is a fluorescent dye binding to mitochondria, thus reducing the intact mitochondria number and inhibiting mitochondrial metabolic activity. Resultantly, the respiratory chain functioning becomes blocked, the cell "suffocated" and eventually destroyed. Unlike normal cells, malignant cells demonstrate a priori reduced mitochondrial numbers and aberrant metabolism. Therefore, a turning point might exist, when ...
Petter Michaela - - 2013
Histone variants are important components of eukaryotic chromatin and can alter chromatin structure to confer specialized functions. H2B variant histones are rare in nature but have evolved independently in the phyla Apicomplexa and Trypanasomatida. Here, we investigate the apicomplexan-specific Plasmodium falciparum histone variant Pf H2B.Z and show that within nucleosomes ...
Anggorowati Nungki - - 2013
GB virus C (GBV-C) is a human virus of the Flaviviridae family that is structurally and epidemiologically closest to hepatitis C virus (HCV), and has been reported to confer beneficial outcomes in HIV-positive patients. However, the presence of GBV-C in HIV-positive individuals in Indonesia was unknown. Since the prevalence of ...
Smetana K - - 2013
Perinucleolar region was studied in lymphocytes of patients suffering from chronic B lymphocytic leukemia to provide more information on the perinucleolar-condensed chromatin - heterochromatin - during the maturation of these cells. The perinucleolar heterochromatin of lymphocytes in smear preparations was visualized using a simple, but sensitive cytochemical method for the demonstration of ...
Yin Huanshun - - 2013
A label-free electrochemical immunosensor for ultra-sensitive detection of indole-3-acetic acid (IAA), a very important phytohormone, has been developed in this work. The detection strategy was mainly based on 4-aminophenylboronic acid, magnetic nanoparticles functionalized with horseradish peroxidase-conjugated goat anti-rat immunoglobulin G (HRP-IgG-Fe(3)O(4)) and rat monoclonal antibody against IAA-modified gold nanoparticles (anti-IAA-AuNPs). ...
Golden Emily - - 2013
The crystal structure of wild-type form of glutaryl-7-ACA acylase from Pseudomonas N176 and a double mutant of the protein (His57βSer/His70βSer) that displays enhanced catalytic efficiency on cephalosporin C over glutaryl-7-aminocephalosporanic acid has been determined. The structures show a heterodimer made up of an α chain (229 residues) and a β ...
Halder Debasish - - 2013
Fetal alcohol spectrum disorder (FASD) is a set of developmental malformations caused by excess alcohol consumption during pregnancy. Using an in vitro system, we examined the role that chronic ethanol (EtOH) exposure plays in gene expression changes during the early stage of embryonic differentiation. We demonstrated that EtOH affected the ...
Nadjar Agnes - - 2013
Activation of the immune system elicits several behavioral changes collectively called sickness. Among the behavioral changes, systemic infections induce an increase in time spent in nonrapid-eye-movement (NREM) sleep and an increase of slow wave activity (or "sleep pressure"). Using an inducible, astrocyte-specific transgenic dominant negative SNARE (dnSNARE) mouse line we ...
Cho Kyu Suk - - 2013
Tissue plasminogen activator (tPA) is expressed in several regions of brain and plays regulatory roles such as neurite outgrowth, synaptic plasticity and long term potentiation. The activity of tPA is regulated by an endogenous inhibitor plasminogen activator inhibitor-1 (PAI-1), which is expressed mainly in astrocytes. Valproic acid (VPA), a histone ...
Zhao Jingjin - - 2013
A novel label-free fluorescent strategy for the detection of glutathione (GSH) and cysteine (Cys) is presented. The system consists of two single stranded DNA (ssDNA) with thymine-thymine (T-T) mismatches and used Hg(2+) as a mediator, and N-methyl mesoporphyrin IX (NMM) as the signal reporter. The assay is based on the ...
Liu Yuanyuan - - 2013
The role of collector surface charge heterogeneity on transport of Cryptosporidium parvum oocyst and carboxylate microsphere in 2-dimensional micromodels was studied. The cylindrical silica collectors within the micromodels were coated with 0, 10, 20, 50, and 100% Fe2O3 patches. The experimental values of average removal efficiencies (η) of the Fe2O3 ...
Sengupta S - - 2013
BACKGROUND AND PURPOSE: Estrogen receptor alpha (ERα) binds to different ligand which can function as complete / partial estrogen-agonist or antagonist. This depends on the chemical structure of the ligands which modulates the transcriptional activity of the estrogen-responsive genes by altering the conformation of the liganded-ERα complex. This study determined ...
Kolarik D - - 2013
The aim of this study is to determine the combination of characteristics in early breast cancer that could estimate the risk of occurrence of metastatic cells in axillary sentinel lymph node(s). If we were able to reliably predict the presence or absence of axillary sentinel involvement, we could spare a considerable ...
Obata Jyun-Ei - - 2013
OBJECTIVES: This study examined whether sirolimus-eluting stent (SES) implantation exerts an anti-proliferative action on a bare metal stent (BMS) placed distally in the same coronary artery. BACKGROUND: Diffusion of sirolimus into flowing coronary blood may cause accumulation of this drug in the coronary bed beyond the distal edge of an ...
Khattab Ahmed A - - 2013
OBJECTIVES: We sought to evaluate the strategy success and short term clinical outcomes of direct stenting via 5 French (F) diagnostic catheters using a novel bare metal stent with integrated delivery system (Svelte Medical Systems, New Providence, New Jersey, USA) and compare the results to a conventionally treated matched group. ...
Zhang Y - - 2013
Arsenic trioxide (ATO) has been demonstrated to induce apoptosis in retinoblastoma cells, however, mechanisms responsible for this phenomenon are not fully understood. In the present study, we determined whether ATO induced apoptosis by abnormal expression of microRNA. In an apoptosis model of retinoblastoma cells subjected to 4 μM ATO for ...
Börsch Michael - - 2013
Optical microscopy of single F(1) -ATPase and F(o) F(1) -ATP synthases started 15 years ago. Direct demonstration of ATP-driven subunit rotation by videomicroscopy became the new exciting tool to analyze the conformational changes of this enzyme during catalysis. Stimulated by these experiments, technical improvements for higher time resolution, better angular ...
Gotoh Ryo O - - 2013
Simple sequence repeats (SSRs) have become one of the most popular molecular markers for population genetic studies. The application of SSR markers has often been limited to source species because SSR loci are too labile to be maintained in even closely related species. However, a few extremely conserved SSR loci ...
Wang Dongniu - - 2013
Hierarchical carbon encapsulated tin (Sn@C) embedded graphene nanosheet (GN) composites (Sn@C-GNs) have been successfully fabricated via a simple and scalable one-step chemical vapor deposition (CVD) procedure. The GN supported Sn@C core-shell structures consist of a crystalline tin core, which is thoroughly covered by a carbon shell and more interestingly, extra ...
Lövdahl S - - 2013
Sweden has been a pioneer in the treatment of haemophilia, with the first concentrate available in the 1950s. Treatment has improved over the years to its current state-of-the art. The aim of the current study was to evaluate the long-term outcome of haemophilia in terms of incidence, morbidity and mortality. ...
Skaaby Tea - - 2013
Vitamin D is associated with cardiovascular disease and renal function but the mechanisms are as yet unexplained. Microalbuminuria is associated with a higher risk of kidney function loss, cardiovascular disease, and mortality. Parathyroid hormone is a predictor of cardiovascular mortality and negatively correlated with glomerular filtration rate. We investigated the ...
Yee S - - 2013
The purpose of this study was to survey the current state of oncology sperm banking services provided by fertility clinics across Canada. A total of 78 Canadian fertility facilities were invited to complete a questionnaire related to the availability, accessibility, affordability and utilisation of sperm banking services for cancer patients. ...
Demiral S - - 2013
The purpose of this study is to evaluate the use of linear accelerator (LINAC)-based stereotactic body radiotherapy (SBRT) boost with multileaf collimator technique after pelvic radiotherapy (RT) in patients with endometrial cancer. Consecutive patients with endometrial cancer treated using LINAC-based SBRT boost after pelvic RT were enrolled in the study. ...
Liu Ziru - - 2013
The objective of this study was to quantify transport of Eu colloids in the vadose zone at the semi-arid Hanford site. Eu-hydroxy-carbonate colloids, Eu(OH)(CO3) were applied to the surface of field lysimeters and migration of the colloids through the sediments was monitored using wick samplers. The lysimeters were exposed to ...
Lavergne Rose-Anne - - 2013
Candida spp. are an important cause of nosocomial bloodstream infections. Currently, complete identification of yeasts with conventional methods takes several days. We report here the first evaluation of an extraction method associated with the Vitek MS matrix-assisted laser desorption ionization time of flight mass spectrometry for direct identification of Candida ...
Hwang Seung-Lark - - 2013
BACKGROUND AND PURPOSE: ER stress has been implicated in the pathogeneses of insulin resistance and type 2 diabetes, and extracellular signal-regulated kinase (ERK) antagonist is an insulin sensitizer that can restore muscle insulin responsiveness in both tunicamycin-treated muscle cells and type 2 diabetic mice. The present study was undertaken to ...
Suzuki Kazushi - - 2013
Abstract We report a 14-year-old boy with a large intrahepatic portosystemic venous shunt. The shunt seemed to be difficult to coil embolize because it was so large and short. However, it was successfully treated by coil embolization with a new dual microcatheter-dual detachable coil technique.
Metgud R - - 2013
Xylene customarily has been used as a clearing agent for routine tissue processing. Because xylene is a relatively hazardous solvent, laboratories are under pressure to seek less toxic alternatives for routine use. We prepared 30 paired soft tissue specimens for routine histopathological evaluation using conventional xylene and xylene-free methods to ...
Nagai Yasutaka - - 2013
Using an operando time-resolved XAFS technique at the Cu and Ce K-edges, we have discovered that the synchronization of Cu and Ce valence change in Cu/CeO(2) under periodic (rich-lean cycling) operation can improve the catalytic activity for NO reduction at low temperature.
Duque-Afonso J - - 2013
Allogeneic hematopoietic cell transplantation (allo-HCT) of older or patients with comorbidities has become possible due to new regimens for reduced-intensity conditioning. The use of fludarabine, carmustine and melphalan as the preparative regimen (FBM) reduces toxicity while providing substantial anti-leukemic activity. Chronic GVHD (cGVHD) of the lung or bronchiolitis obliterans syndrome ...
Marazziti Donatella - - 2013
Data on the specific effects of sex on pharmacokinetics, as well as tolerability, safety, and efficacy of psychotropic medications are still meager, mainly because only recently sex-related issues have attracted a certain degree of interest within the pharmacological domain. Therefore, with the present study, we aimed to provide a comprehensive ...
Z-X Wu - - 2013
Abstract Single nucleotide polymorphism (SNP) of programmed cell death 1 (PD-1) has been reported to associate with several autoimmune diseases including rheumatoid arthritis (RA), Graves' disease and multiple sclerosis (MS). In order to study the correlation between PD-1 gene polymorphism and aplastic anemia (AA) in Chinese Han population, two SNPs, ...
Wilkerson Elizabeth Dalee - - 2013
Two portable infrared sensors were evaluated for the rapid determination of quality parameters in processing tomatoes. A total of 370 hot-break juices were prepared from ~40 processing tomato varieties grown in 5 California counties. The levels of sugars, acids, soluble solids, titratable acidity, and pH in these juices were determined ...
Gibson Teresa B - - 2013
We examined whether outcomes of care (amputation and hospitalisation) among patients with diabetes and foot ulcer differ between those who received pre-ulcer care from podiatrists and those who did not. Adult patients with diabetes and a diagnosis of a diabetic foot ulcer were found in the MarketScan Databases, 2005-2008. Multivariate ...
Lin Y-H - - 2013
Hypothyroidism has been associated with significantly elevated risk for hepatocellular carcinoma (HCC), although the precise underlying mechanisms remain unknown at present. Thyroid hormone (T(3)) and its receptor (TR) are involved in metabolism and growth. Endoglin is a T(3)/TR candidate target gene identified from our previous studies. Here, we demonstrated that ...
Kako S - - 2013
The efficacy of unrelated transplantation for patients with ALL who lack an HLA-matched sibling remains unclear. We performed a decision analysis to determine the efficacy of myeloablative transplantation from a genetically HLA-A, -B, -DRB1 allele-matched unrelated donor for patients with Ph chromosome-negative ALL aged 21-54 years. The transition probabilities were ...
Ryugo Masahiro - - 2013
A 58-year-old male with no history of heart disease was admitted to hospital for congestive heart failure due to severe left ventricular dysfunction, and clinically diagnosed with dilated cardiomyopathy. He developed recurrent heart failure requiring several admissions to hospital and was finally referred to our institution with severe congestive heart ...
Huang Yuahn-Sieh - - 2013
Mesenchymal stromal/stem cells (MSCs) are widely distributed in different tissues such as bone marrow, adipose tissues, peripheral blood, umbilical cord and amnionic fluid. Recently, MSC-like cells were also found to exist in rat olfactory bulb and are capable of inducing differentiation into mesenchymal lineages - osteocytes, chondrocytes and adipocytes. However, ...
Low Daniel K - - 2013
AIMS: We describe our aim to create a zero-error system in our pediatric ambulatory surgery center by employing effective teamwork and aviation-style challenge and response 'flow checklists' at key stages of the patient surgical journey. These are used in addition to the existing World Health Organization Surgical Safety Checklists (Ann ...
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