Search Results
Results 201 - 250 of 4952
< 1 2 3 4 5 6 7 8 9 10 >
Xu Yan - - 2013
A technical bottleneck to the broadening of applications of glass nanofluidic chips is bonding, due to the strict conditions, especially the extremely high temperatures (∼1000 °C) and the high vacuum required in the current glass-to-glass fusion bonding method. Herein, we report a strong, nanostructure-friendly, and high pressure-resistant bonding method, performed ...
Yijing Lv - - 2013
Abstract Context: Qindan capsule (QC), a compound used in traditional Chinese medicine, has been used as an anti-hypertensive agent in clinical settings for years. Our previous studies have shown that QC can improve the morphological index of the artery, down-regulate the collagen volume fraction in the media and inhibit the ...
Jereczek-Fossa B A - - 2013
Electronic portal imaging (EPI) is commonly used to identify and correct for inter-fraction variability in tangential breast irradiation. Based on the institutional policy, EPI registration is performed by either radiation oncologist or therapist. Little data is available on the inter-observer agreement in EPI registration among different health practitioners. The aim ...
Del Rio Jose Carlos - - 2013
The chemical composition of the lipids in wheat straw was studied in detail by gas chromatography and mass spectrometry. Important discrepancies with the data reported in previous papers were found. The predominant lipids identified were series of long-chain free fatty acids (25 % of total extract), followed by series of ...
Dougan Brooke K - - 2013
The objective of this study is to determine which pre-existing athlete characteristics, if any, are associated with greater deficits in functioning following sports-related concussion, after controlling for factors previously shown to moderate this effect (e.g., time since injury). Ninety-one independent samples of concussion were included in a fixed+systematic effects meta-analysis ...
Hosokawa S - - 2013
Transverse acoustic (TA) excitation modes were observed in inelastic x-ray scattering (IXS) spectra of liquid Sn. The excitation energies and widths of the TA modes are in good agreement with results of an ab initio molecular dynamics simulation. By comparing current correlation spectra between the experimental and theoretical results quantitatively, ...
Fu Yunyun - - 2013
Marine Rhodobacterales are recognized as a widespread, abundant, and metabolically versatile bacterial group in the World's Oceans. They also show a nearly universal conservation of the genes for production of gene transfer agents (GTAs), virus-like particles that mediate genetic exchange between cells. It is not yet clear what factors determine ...
Flacco N - - 2013
BACKGROUND AND PURPOSE: To analyse the relative contribution of β(1) -, β(2) - and β(3) -adrenoceptors (ARs) to vasodilatation in conductance and resistance vessels, assessing the role of cAMP and/or NO/cGMP signalling pathways. EXPERIMENTAL APPROACH: Rat mesenteric resistance artery (MRA) and aorta were used to analyse the β-ARs expression by ...
Brandberg C - - 2013
BACKGROUND: By 2050, the percentage of the population older than 80 years will double, and some data suggest that elderly patients receive less advanced treatment. Information of outcome in elderly (≥ 65 year), representing roughly half the intensive care unit (ICU) admissions, in Sweden is scarce. METHODS: Retrospective cohort study. We ...
Roychoudhury A N - - 2013
Here, we report on the spatial and temporal variation in sulphate-reducing bacterial community structure and activity in three hypersaline coastal pans. Community structure was determined using denaturing gradient gel electrophoresis (DGGE). Cluster analysis of DGGE patterns indicated that similar microbial populations were generally found in individual pans but varied from ...
He Xiao-Yan - - 2013
Abstract Context: Qi-Wei-Xiao-Yan-Tang (XYT), composed of Radix et Rhizoma Rhei, Radix Astragali, Radix Wikstroemiae Indicae, Fructus Ligustri Lucidi, Poria and Radix Glycyrrhizae, has been widely used as an anti-inflammatory drug. Objective: The present study investigated the anti-inflammatory, antibacterial effects and serum pharmacochemistry of XYT. Methods: The dimethylbenzene-induced inflammation test, the ...
Wang Huan - - 2013
The orientation factor κ(2) ranging from 0 to 4, which depends on the relative orientation of the transition dipoles of the energy donor (D) and the energy acceptor (A) in space, is one of the pivotal factors deciding the efficiency and directionality of resonance energy transfer (RET) in a D-A ...
Senet Patricia - - 2013
Biatain and Biatain-Ag are two identical wound dressings except the fact that Biatain-Ag releases silver. In the present multinational double-blinded randomised controlled trial the effect of the two dressings were compared for treatment of venous leg ulcers. A total of 181 patients were treated for 6 weeks with either Biatain or ...
Villa L - - 2013
BACKGROUND AND PURPOSE: α(1) -adrenoceptor (-AR) antagonists may facilitate ureter stone passage in humans. We aimed to study effects by the α(1A) -AR selective antagonist silodosin (compared to tamsulosin and prazosin) on ureter pressures in a rat model of ureter obstruction, and on contractions of human and rat isolated ureters. ...
Zhang Hai-Liang - - 2013
The skeleton is the most common metastatic organ in patients with prostate cancer (PCa). Non-invasive biomarkers that can facilitate the detection and monitoring of bone metastases are highly desirable. We designed this study to assess the expression patterns of serum miR-141 in patients with bone-metastatic PCa. Serum samples were collected ...
Badrick Ellena - - 2013
BACKGROUND: This quality improvement project was set in Tower Hamlets, east London, with the aim of reducing health inequalities by ethnicity, age and gender in the management of three common chronic diseases. METHODS: Routinely collected clinical data were extracted from practice computer systems using Morbidity Information Query and Export Syntax ...
Syed M I - - 2013
Background: The key to avoiding damage to the horizontal facial nerve in middle-ear surgery is to formally identify the nerve in the early stages of the procedure. Methods: In the non-infected ear this can be achieved relatively easily by identifying the oval window niche. However, in the infected ear with ...
Lazenby Robert A - - 2013
Hopping intermittent contact-scanning electrochemical microscopy (HIC-SECM) is introduced as a powerful new technique for the quantitative visualization of redox activity and concentration at and above a surface of interest. HIC-SECM combines a hopping imaging mode, in which data are acquired at a tip as a function of distance (z) from ...
Sabova L - - 2013
NF1 proteins are a family of transcription factors that act either as repressors or as activators. Functional studies indicate that NF1 participate in signaling pathways that regulate cell viability, proliferation and differentiation. Participation in regulation of genes important for tumor progression and metastasizing suggests a potential value of NF1 as a prognostic factor ...
Ung Kjell-Arne - - 2013
Abstract Background. Self-expandable metallic stents (SEMS) placement is a standard treatment for inoperable malignant bile duct strictures. Covered SEMS have been introduced to avoid stent occlusion by tumor ingrowth. The aims were to compare covered and uncovered stents in terms of patency, efficacy and complication rate. Material and methods. Consecutive ...
Korehi Hananeh - - 2013
The marine shore sulfidic mine tailings dump at the Chañaral Bay in the Atacama Desert, northern Chile, is characterized by extreme acidity, high salinity and high heavy metals concentrations. Due to pyrite oxidation, metals (especially copper) are mobilized under acidic conditions and transported towards the tailings surface and precipitate as ...
Saeki Tohru - - 2013
ABSTRACT: BACKGROUND: SLC10A2-mediated reabsorption of bile acids at the distal end of the ileum is the first step in enterohepatic circulation. Because bile acids act not only as detergents but also as signaling molecules in lipid metabolism and energy production, SLC10A2 is important as the key transporter for understanding the ...
Gershkovich Pavel - - 2013
Abstract Purpose: To develop and to validate a simple but sensitive method for determination of vitamins D(3) and K(1) in rat plasma. Methods: The sample treatment included protein precipitation by cold acetonitrile, evaporation, reconstitution with methanol and filtration. The chromatography conditions included Xterra RP18 3.5 µm 4.6 × 100 mm column at ambient temperature ...
Salinas Yolanda - - 2013
Mesoporous silica nanoparticles capped with TTF moieties and containing a ruthenium dye in the pores were used for the turn-on optical detection of the nitroaromatic explosives Tetryl and TNT via a selective pore uncapping and release of the entrapped dye.
Kalpana Deepa Priya D - - 2013
Abstract Context: Sulforaphane (SFN) [1-isothiocyanato-4-(methylsulfinyl)butane] is a naturally occurring isothiocyanate found in cruciferous vegetables such as broccoli [Brassica oleracea L. var. italica Plenck. (Brassicaceae)]. Since it is among the most potent bioactive components with antioxidant and antitumor properties, it has received intense attention in the recent years for its chemopreventive ...
Tanguy Ronan - - 2013
Brain metastases management is still controversial even though many trials are trying to define the respective roles of neurosurgery, whole-brain radiotherapy, single-dose stereotactic radiotherapy and fractionated stereotactic radiotherapy. In this article, we review data from trials that examine the role of radiosurgery and fractionated stereotactic radiotherapy in the management of ...
Iino Ichirota - - 2013
Control of liver metastasis is an important issue in the treatment of colorectal cancer (CRC). Micro RNAs (miRNA) have been shown to be involved in the development of many cancers, but little is known about their role in the process of colorectal liver metastasis. We compared miRNA expression between primary ...
Chen Hui - - 2013
Reactions of [Mn(6)O(2)(piv)(10)(py)(2.5)(piv)(1.5)], Ln(NO(3))(3)·6H(2)O and N-mdeaH(2) in MeCN in the presence of Me(3)SiCl generated a family of octanuclear Mn/Ln complexes [Mn(6)(III)Mn(II)Ln(N-mdea)(3)(N-mdeaH)(piv)(8)O(2)(OH)(3)(NO(3))(H(2)O)]·xCH(3)CN·xH(2)O [Ln = Gd (), Dy (), Er (), pivH = pivalic acid, N-mdeaH(2) = N-methyl diethanolamine]. Each complex possesses a [Mn(6)(III)Mn(II)Ln(μ(3)-O)(2)(μ(3)-OH)(3)](16+) core containing two butterfly-like subunits of [Mn(3)Ln(μ(3)-OH)(2)] and ...
Mautz Brian S - - 2013
There are two reasons why researchers are interested in the phenotypic relationship between the expression of male secondary sexual characters (SSCs) and 'ejaculate quality' (defined as sperm/ejaculate traits that are widely assumed to increase female fertility and/or sperm competitiveness). First, if the relationship is positive then females could gain a ...
Wang Jirui - - 2013
Hexaploid wheat (Triticum aestivum, genomes AABBDD) originated by hybridization of tetraploid Triticum turgidum (genomes AABB) with Aegilops tauschii (genomes DD). Genetic relationships between A. tauschii and the wheat D genome are of central importance for the understanding of wheat origin and subsequent evolution. Genetic relationships among 477 A. tauschii and wheat accessions ...
Tanaka Yoko - - 2013
The number and density of stomata is controlled by endogenous and environmental factors.Despite recent advances in our understandingof stomatal development, mechanismswhich preventstomatal lineage entry remain unclear. Here, we propose that abscisic acid (ABA), a phytohormone known to induce stomatal closure, limits initiation of stomatal developmentand induces enlargement of pavement cells ...
Santiago Piedad - - 2013
The benefits of iodine supplements during pregnancy remain controversial in areas with a mild-to-moderate iodine deficiency. The aim of the present study was to determine the effect of improving iodine intakes, with iodised salt (IS) or iodine supplements, in pregnant Spanish women. A total of 131 pregnant women in their ...
Rosenow F - - 2013
After allo-SCT, analysis of CD34(+) lineage-specific donor cell chimerism (DCC) is a sensitive method for monitoring minimal residual disease in patients with AML or myelodysplastic syndrome (MDS) with CD34 expression. To substantiate evidence of whether immune interventions in patients with impending relapse, defined by incomplete lineage-specific DCC, may prevent hematological ...
Riehn K - - 2013
The trematode Alaria alata, an intestinal parasite of different carnivore species is widely distributed throughout Europe. The mesocercarial stages of Alaria spp. may infect almost all vertebrate species, including humans, and, in particular, omnivorous scavengers such as wild boars serve as paratenic hosts for the parasite. The introduction of the ...
Xiao Da - - 2013
AIMS: For four decades, 5-fluorouracil (5-FU) has been a major anticancer medicine. This drug is increasingly used with other anticancer agents such as irinotecan. Irinotecan and many others such as PPD (pentyl carbamate of p-aminobenzyl carbamate of doxazolidine) require activation by carboxylesterase-2 (CES2). 5-FU, on the other hand, reportedly induces ...
Kim Young Ran - - 2013
Vibrio vulnificus causes fatal septicemia in susceptible subjects after the ingestion of raw seafood. In the present study, we investigated the roles of the cAMP receptor protein (CRP) in V. vulnificus pathogenesis. A mutation in the V. vulnificus crp gene resulted in a significant down-regulation of various virulence phenotypes, except ...
Barwood Caroline H S - - 2013
Language impairments are reported in multiple sclerosis (MS). To date, the majority of studies have evaluated language differences between relapsing-remitting (RR) and chronic progressive (CP) clinical courses. Neurologists have distinguished two progressive courses of MS: primary progressive (PP) MS and secondary progressive (SP) MS. Recent evidence suggests that cognitive performance ...
Romano B - - 2013
BACKGROUND AND PURPOSE: The non-psychotropic cannabinoid cannabichromene is known to activate the transient receptor potential ankyrin-type1 (TRPA1) and to inhibit endocannabinoid inactivation, both of which are involved in inflammatory processes. We examined here the effects of this phytocannabinoid on peritoneal macrophages and its efficacy in an experimental model of colitis. ...
Hortolà Policarp - - 2013
Studies of human bloodstains on nonbiological materials have been previously carried out using a high-vacuum scanning electron microscope (HV-SEM) in secondary-electron mode without any sample treatment. To assess whether biological substrates can affect the morphology of human erythrocytes in bloodstains, three fragments of different biological material (bone, shell, and wood) ...
Randall Sue - - 2013
Aim To consider findings from a study that evaluated case management of individuals with long-term conditions (LTCs) by a community matron (CM) service. The paper highlights issues related to the implementation of a new role and the impact this had on the experience of care across hospital and community settings ...
Tseng L M - - 2013
Triple-negative breast cancer (TNBC) relapses more frequently than hormone receptor-positive subtypes and is often associated with poor outcomes. This retrospective study reviewed the pattern of distant metastasis with regard to survival in patients with TNBC. A total of 205 TNBC patients were analyzed. TNBC patients with lung metastases had the longest ...
Liu H - - 2013
Objectives: To explore the mechanism about how HMG-CoA reductase (HMGR) inhibitor inhibit proliferation and bone metastases of lung adenocarcinoma in vitro and in vivo. Methods: The HMGR inhibitor simvastatin, human lung cancer cell line A549 and Balb/c nude mouse were used in this study. The mice were randomly divided into ...
Jaul Efraim - - 2013
Atypical pressure ulcers (APU) are distinguished from common pressure ulcers (PU) with both unusual location and different aetiology. The occurrence and attempts to characterise APU remain unrecognised. The purpose of this cohort study was to analyse the occurrence of atypical location and the circumstances of the causation, and draw attention ...
Yang B - - 2013
The purpose of this study was to evaluate the association of expression level of α5β1-integrin and MMP-14 with clinicopathologic features and prognosis in colorectal cancer (CRC). The expressions of α5β1-integrin and MMP-14 in normal colorectal mucosa and CRC tissue were detected with immunohistochemistry. We estimated the five-year survival rate by ...
French Tracy - - 2013
OBJECTIVE: The Disease Activity Score in 28 joints (DAS28) is a key measure in clinical practice and clinical trials. There are at least five different versions of the 'Patient Global' Visual Analogue Scale (PG-VAS) being used in the DAS28. The developers suggested that the PG-VAS can be an assessment of ...
Rosen Raymond C - - 2013
Abstract Objective: Despite the prevalence of hypogonadism (HG) and widespread use of testosterone therapy, little is known about the safety/effectiveness of long-term testosterone use. The Registry of Hypogonadism in Men (RHYME) is a multi-national patient registry assessing prostate health and other outcomes associated with testosterone treatment in men. Design: Observational ...
Kim Sung-Dae - - 2013
The seriousness of metabolic syndrome is not due to the disease itself but its promotion of other diseases, such as erectile dysfunction and cardiovascular and cerebrovascular diseases. We investigated the effects of Korean red ginseng (KRG, Panax ginseng) extract on erectile function in a rat model of metabolic syndrome. We ...
Sborov Douglas W - - 2013
Acquired haemophilia A (AHA) is a potentially life-threatening bleeding disorder occurring in patients without a previous personal or family history of bleeding. Development of immune-mediated autoantibodies against coagulation factor VIII is associated with a wide range of clinical disorders including pregnancy, autoimmune disorders, malignancy, or with no apparent disease. There ...
Ku Janice J-Y - - 2013
To assess the accuracy of grading diabetic retinopathy (DR) using single-field digital fundus photography compared with clinical grading from a dilated slit-lamp fundus examination in Indigenous Australians living in Central Australia. Cross-sectional study comparing DR grades in participants with diabetes mellitus presenting for examination at remote community clinics from 1 July ...
Park Youn Hee - - 2013
ABSTRACT: BACKGROUND: Hypothermic protection against ischemic stroke has been reported by many studies. Hypothermia is supposed to mitigate the effects of deleterious genes and proteins and promote the activity of protective genes and proteins in the ischemic brain. Metallothionein (MT)-1/2 is thought to be a crucial factor for metal homeostasis, ...
< 1 2 3 4 5 6 7 8 9 10 >