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Plyler Patrick N - - 2013
Background: Multichannel wide dynamic range compression (WDRC) and ChannelFree processing have similar goals yet differ significantly in terms of signal processing. Multichannel WDRC devices divide the input signal into separate frequency bands; a separate level is determined within each frequency band; and compression in each band is based on the ...
Chekerov Radoslav - - 2013
INTRODUCTION: The Sixth Framework Program European Union project OVCAD, "Ovarian Cancer-Diagnosis of a Silent Killer," aimed to investigate new predictors for early detection of minimal residual disease in epithelial ovarian cancer (EOC). Here we present the main pathologic, surgical, and chemotherapy characteristics of the OVCAD patient cohort. METHODS: Between February ...
Neil Janice A - - 2013
Obesity has become a major health concern in the United States. The number of patients seeking bariatric surgery has grown exponentially in recent years because of the proven success of weight-loss surgery, greater public acceptance, and the increasing number of insurers who will pay for these surgeries. Patients may seek ...
Chen Lifeng - - 2013
The objective of this study was to explore the clinical significance of survivin expression in epithelial ovarian cancer (EOC) and the effect of survivin small hairpin RNA (shRNA) on survivin expression, apoptosis, and chemosensitivity in the human ovarian cancer cell line OVCAR3. A retrospective review of 90 consecutive EOC patients ...
de Vooght Karen M K - - 2013
Blood contains a mixture of extracellular vesicles from different cell types, primarily platelets, endothelial cells, leucocytes and erythrocytes. Erythrocytes are the most abundant cell type in blood and could, especially in certain pathologies, represent an important source of vesicles. Since erythrocytes contain the haemoglobin components iron and haem, which are potentially ...
Milescu Mirela - - 2013
Voltage-activated ion channels open and close in response to changes in membrane voltage, a property that is fundamental to the roles of these channels in electrical signaling. Protein toxins from venomous organisms commonly target the S1-S4 voltage-sensing domains in these channels and modify their gating properties. Studies on the interaction ...
Asfar Omar - - 2013
In this paper, guided ultrasonic wave propagation is analyzed in an elastic plate with sinusoidal surface corrugations. The corrugated area acts as a finite-length grating which corresponds to a 1-D phononic crystal (PC). The multiple-scale perturbation technique is used to derive coupled-mode equations describing the amplitudes of interacting modes. These ...
Musser Erica D ED Oregon Health and Science University, Portland, OR 97239, USA. - - 2013
How best to capture heterogeneity in attention-deficit/hyperactivity disorder (ADHD) using biomarkers has been elusive. This study evaluated whether emotion reactivity and regulation provide a means to achieve this. Participants were classified into three groups: children with ADHD plus low prosocial behavior (hypothesized to be high in callous/unemotional traits; n = ...
Mistraletti Giovanni - - 2013
The performances of 2 noninvasive CPAP systems (high flow and low flow air-entrainment masks) were compared to the Boussignac valve in 3 different scenarios. Scenario 1: pneumatic lung simulator with a tachypnea pattern (tidal volume 800 mL at 40 breaths/min). Scenario 2: Ten healthy subjects studied during tidal breaths and ...
Ide Patricia - - 2013
The number of people who are obese or morbidly obese is increasing in the United States. Currently, the most effective means of losing a substantial amount of weight and maintaining the weight loss is bariatric surgery, and health care providers, especially those in surgical services, must be able to safely ...
Camussi Giovanni - - 2013
The paracrine theory has recently changed the view of the biological action of stem cells and of the subsequent potential application of stem cells in regenerative medicine. Indeed, most of the beneficial effects of stem-cell-based therapy have been attributed to soluble factors released from stem cells. In this context, MVs ...
Vanoye Carlos G - - 2013
Tetrodotoxin (TTX)-resistant voltage-gated Na (Na(V)) channels have been implicated in nociception. In particular, Na(V)1.9 contributes to expression of persistent Na current in small diameter, nociceptive sensory neurons in dorsal root ganglia and is required for inflammatory pain sensation. Using ND7/23 cells stably expressing human Na(V)1.9, we elucidated the biophysical mechanisms ...
Nikolovski Jean-Pierre - - 2013
This paper presents an active stylus (X, Y) flat digitizing tablet (AST). The tablet features an acquisition rate of 1000 pts/s with 0.1 mm resolution. The cordless stylus incorporates a 1-mA low-power pulse generator. Precision is limited by diffraction to about ±0.3 mm on a 57 x 57 mm region ...
Fisher Daniel F - - 2013
Presence of a tracheostomy tube often decreases the patient's ability to communicate and to tolerate oral intake. The initial tracheostomy tube change is often recommended between day 7 and 14 post insertion. Local guidelines permit tracheostomy tube change 5 days after insertion. We hypothesized that changing tracheostomy tubes before day ...
Lima Marina Guimarães MG Departamento de Farmácia Social, Faculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil. - - 2013
Congenital syphilis continues to be a public health problem in Brazil. The scope of this study is to describe the trends in the incidence of congenital syphilis in Belo Horizonte between 2001 and 2008 and determine risk factors associated with disease diagnosis. Data on cases of congenital syphilis and on ...
Chivet Mathilde - - 2013
Exosomes are small extracellular vesicles which stem from endosomes fusing with the plasma membrane; they contain lipids, proteins and RNAs that are able to modify receiving cells. Functioning of the brain relies on synapses, and certain patterns of synaptic activity can change the strength of responses at sparse groups of ...
Evguenieva-Hackenberg Elena - - 2013
RNA stability control and degradation are employed by cells to control gene expression and to adjust the level of protein synthesis in response to physiological needs. In all domains of life, mRNA decay can commence in the 5'-3' as well as in the 3'-5'-direction. Consequently, mechanisms are in place conferring ...
Duryea Alexander P - - 2013
Stone comminution in shock wave lithotripsy (SWL) has been documented to result from mechanical stresses conferred directly to the stone, as well as the activity of cavitational microbubbles. Studies have demonstrated that the presence of this cavitation activity is crucial for stone subdivision; however, its exact role in the comminution ...
Alajmi Hasan H HB Williams Craniofacial and Cleft Surgery Unit, Montreal Children's Hospital, Montreal, Quebec, - - 2013
For cleft teams that use nasoalveolar molding for presurgical treatment of cleft lips, the determination of desired cleft-nasal height correction is a subjective assessment. The latter, however, is complicated by a noncleft nasal height that itself is depressed by the shifted nasal pyramid native to the deformity. The authors introduce ...
Serra Fernando F Plastic Surgery Service, Pedro Ernesto University Hospital, Rio de Janeiro, Brazil. - - 2013
New surgical techniques for gluteal augmentation have improved final results. It is estimated that more than 35,000 patients have undergone augmentation gluteoplasty using implants. The authors sought to determine and quantify the presence of muscle atrophy, and to evaluate implant positioning using the intramuscular technique. Twenty-three female patients were selected ...
Perfetti Charles A - - 2013
Do differences in writing systems translate into differences in the brain's reading network? Or is this network universal, relatively impervious to variation in writing systems? A new study adds intriguing evidence to these questions by showing that reading handwritten words activates a pre-motor area across writing systems.
Richmond Amanda L - - 2013
Summoned from overseas, a husband and father finds a drastically altered future.
Muniz Ludmila Correa - - 2013
This is a cross-sectional school-based study that evaluated the prevalence and associated factors of the daily intake of fruit and vegetables by adolescents at public schools in Caruaru, Pernambuco. Poisson regression with a hierarchical model, including sociodemographic variables in the first hierarchical level, behavioral variables in the second and diet-related ...
Thomas Gareth M GM Shriners Hospital Pediatric Research Center (Center for Neurorehabilitation and Neural Repair), Temple University Medical School, 3500 N. Broad Street, Philadelphia, PA 19130, USA. - - 2013
In recent years, it has become clear that both AMPA (α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid)- and NMDA (N-methyl-D-aspartate)-type glutamate receptors, and many of their interacting partners, are palmitoylated proteins. Interfering with palmitoylation dramatically affects receptor trafficking and distribution and, in turn, can profoundly alter synaptic transmission. Increased knowledge of synaptic palmitoylation not only ...
Prasse Daniela - - 2013
sRNAs (small non-coding RNAs) representing important players in many cellular and regulatory processes have been identified in all three domains of life. In Eukarya and Bacteria, functions have been assigned for many sRNAs, whereas the sRNA populations in Archaea are considerably less well characterized. Recent analyses on a genome-wide scale ...
Song Baoqiang B Institute of Plastic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, Fujian, People's Republic of China. - - 2013
Facial scars caused by burns and trauma severely affect patients' function and appearance. The expanded deltopectoral flap to local shift is the traditional method of repair, but for patients with the compulsive position after pedicle transfer, the therapeutic outcome is not satisfactory. The authors explored the surgical procedures for repairing ...
Darling A - - 2013
INTRODUCTION. Oculogyric crises are considered to be a form of focal dystonia and can be observed as reactions to pharma-ceuticals. The signs and symptoms may be confused with epileptic crises. AIMS. To describe the clinical features and progress of patients with pharmaceutical-related oculogyric crises and to carry out a review ...
Nelson Amanda E AE Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, 3300 Doc J. Thurston Building, CB #7280, Chapel Hill, NC 27599, USA. - - 2013
To determine differences in the phenotypes (patterns) of multiple-joint symptomatic osteoarthritis (OA) involvement by race and sex. A cross-sectional analysis of symptomatic OA phenotypes was performed in a community-based cohort, comprising subjects for whom data were collected from 4 sites of symptomatic OA involvement (the hands, knees, hips, and lumbosacral ...
Witwer Kenneth W KW Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. - - 2013
Public sharing of scientific data has assumed greater importance in the omics era. Transparency is necessary for confirmation and validation, and multiple examiners aid in extracting maximal value from large data sets. Accordingly, database submission and provision of the Minimum Information About a Microarray Experiment (MIAME)(3) are required by most ...
Cottet Martin - - 2013
Fluorescent ligands for GPCRs (G-protein-coupled receptors) have been synthesized for a long time but their use was usually restricted to receptor localization in the cell by fluorescent imaging microscopy. During the last two decades, the emergence of new fluorescence-based strategies and the concomitant development of fluorescent measurement apparatus have dramatically ...
Kaminski Lina - - 2013
Although performed by members of all three domains of life, the archaeal version of N-glycosylation remains the least understood. Studies on Haloferax volcanii have, however, begun to correct this situation. A combination of bioinformatics, molecular biology, biochemical and mass spectrometry approaches have served to delineate the Agl pathway responsible for ...
Kahokehr Arman - - 2013
To assess the effects of non-steroidal anti-inflammatory drugs (NSAIDs) in men with benign prostatic hyperplasia (BPH) using systematic review and meta-analysis of clinical trials. Men treated with NSAIDs in comparison with placebo or other BPH medications. All aspects of the Preferred Reporting for Systematic Reviews and Meta-Analyses (PRISMA) statement were ...
Svensson Katrin J - - 2013
Over the last few decades, extensive studies by several groups have introduced the concept of cell-derived secreted extracellular membrane vesicles as carriers of complex molecular information. Owing to their pleiotropic biological effects and involvement in a wide variety of biological processes, extracellular membrane vesicles have been implicated in physiological as ...
Stetter Karl O - - 2013
Hyperthermophiles, growing optimally at 80°C and above were first discovered in 1981. They represent the upper temperature border of life and are found within water-containing terrestrial and submarine environments of active volcanism and geothermally heated subterranean rocks. The energy-yielding reactions represent mainly anaerobic and aerobic types of respiration rather than ...
Camargo Ana Paula Paes de Mello de - - 2013
The goal of this study is to review articles in the scientific literature investigating the role of mothers, fathers and relatives in the treatment of obesity of their children. A search for original articles was conducted in the BIREME (BVS), PUBMED (MEDLINE) and Scielo platforms from 2004 to 2010, using ...
Blackwood John K JK Department of Biochemistry, University of Cambridge, Cambridge CB2 1GA, - - 2013
During DNA repair by HR (homologous recombination), the ends of a DNA DSB (double-strand break) must be resected to generate single-stranded tails, which are required for strand invasion and exchange with homologous chromosomes. This 5'-3' end-resection of the DNA duplex is an essential process, conserved across all three domains of ...
Vig John - - 2013
The SI unit of mass, the kilogram, is defined by a single artifact, the International Prototype Kilogram. This artifact, the primary mass standard, suffers from long-term instabilities that are neither well understood nor easily monitored. A secondary mass standard consisting of a 1-kg quartz resonator in ultrahigh vacuum is proposed. ...
Griffin Andrew - - 2013
Dramatic changes in outpatient surgery have occurred in recent years, but the basic care needs of surgical patients remain constant. Most outpatients face the same spiritual and coping issues that inpatients do, but outpatient surgery requires that patients cope with the surgery at an accelerated pace. This phenomenological study describes ...
Uzan Catherine - - 2013
Vaginal radical trachelectomy (VRT) is the most widely evaluated form of conservative management of young patients with early-stage (IB1) cervical cancer. Patients with nodal involvement or a tumor size greater than 2 cm are not eligible for such treatment. The aim of this study is to report the impact of ...
Inal Jameel M - - 2013
Coxsackievirus B1, a member of the Picornaviridae family is a non-enveloped single-stranded RNA virus associated with human diseases including myocarditis and pancreatitis. Infection of the intestinal mucosa, lined by polarized epithelial cells, requires interaction of coxsackievirus with apically located DAF (decay-accelerating factor) before transport to the basolaterally located CAR (coxsackie ...
Jin Byung-Ju BJ Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, - - 2013
Secretory diarrheas such as cholera are a major cause of morbidity and mortality in developing countries. We previously introduced the concept of antisecretory therapy for diarrhea using chloride channel inhibitors targeting the cystic fibrosis transmembrane conductance regulator channel pore on the extracellular surface of enterocytes. However, a concern with this ...
Yang Song-Ling - - 2013
CuO is doped into (Na(0.5)K(0.5))NbO(3) (NKN) ceramics to improve the piezoelectric properties and thus obtain a piezoelectric transformer (PT) with high output power. In X-ray diffraction patterns, the diffraction angles of the CuO-doped NKN ceramics shift to lower values because of an expansion of the lattice volume, thus inducing oxygen ...
Mueller Sven C SC Development and Affective Neuroscience, National Institute of Mental Health (NIMH), University of Ghent, Belgium. - - 2013
Minimal research links anxiety disorders in adolescents to regional gray matter volume (GMV) abnormalities and their modulation by genetic factors. Prior research suggests that a brain-derived neurotrophic factor (BNDF) Val(66)Met polymorphism may modulate such brain morphometry profiles. Using voxel-based morphometry and magnetic resonance imaging, associations of BDNF and clinical anxiety ...
Lins Ana Paula Machado - - 2013
The scope of this study was to analyze the factors associated with the prevalence of being overweight and obesity in a population of low-income adult women living in a metropolitan region and its association with socioeconomic, demographic, reproductive and lifestyle variables, highlighting the importance of healthy eating. A population-based, cross-sectional ...
Peeters Eveline - - 2013
For cellular fitness and survival, gene expression levels need to be regulated in response to a wealth of cellular and environmental signals. TFs (transcription factors) execute a large part of this regulation by interacting with the basal transcription machinery at promoter regions. Archaea are characterized by a simplified eukaryote-like basal ...
Teixeira Pryscila Dryelle Sousa - - 2013
The scope of this study was to evaluate the effectiveness of two methods of educational nutritional intervention together with women who practice regular physical activities by fostering the adoption of healthy eating habits. The study population consisted of 52 women aged between 19 and 59 who frequented the Academia da ...
Storck Elisabeth M - - 2013
The study of post-translational modifications such as protein lipidation is a non-trivial challenge of the post-genomic era. In recent years the field of chemical proteomics has greatly advanced our ability to identify and quantify protein lipidation. In the present review, we give a brief overview of the tools available to ...
Cooke Robert M - - 2013
Since the publication of the first X-ray structure of a GPCR (G-protein couple receptor) in 2000, the rate at which subsequent ones have appeared has steadily increased. This has required the development of new methodology to overcome the challenges presented by instability of isolated GPCRs, combined with a systematic optimization ...
Driessen Rosalie P C - - 2013
Crenarchaeal genomes are organized into a compact nucleoid by a set of small chromatin proteins. Although there is little knowledge of chromatin structure in Archaea, similarities between crenarchaeal and bacterial chromatin proteins suggest that organization and regulation could be achieved by similar mechanisms. In the present review, we describe the ...
Seth Akhil K AK Division of Plastic and Reconstructive Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Ill 60611, - - 2013
Bacterial biofilms, which are critical mediators of chronic wounds, remain difficult to treat with traditional methods. Bacteriophage therapy against biofilm has not been rigorously studied in vivo. The authors evaluate the efficacy of a species-specific bacteriophage against Staphylococcus aureus biofilm-infected wounds using a validated, quantitative, rabbit ear model. Six-millimeter dermal ...
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